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The work process of research librarians implementation of the abstraction-decomposition space /Simons, Kevin J. January 2005 (has links)
Thesis (Ph.D.)--Miami University, Dept. of Psychology, 2005. / Title from second page of PDF document. Document formatted into pages; contains [2], vi, 72, [22] p. : ill. Includes bibliographical references (p. 35-37).
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Análise temporal dos efeitos preventivos do exercício resistido sobre a atrofia muscular induzida por dexametasona / Temporal analysis of preventive effects of resistance exercise on muscular atrophy induced by dexamethasoneKrug, André Luis de Oliveira 27 March 2018 (has links)
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Previous issue date: 2018-03-27 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Synthetic glucocorticoids have potent anti-inflammatory and immunosuppressive action, though its chronic usage can trigger muscle atrophy. On the other hand the resistance training (RT) acts in opposition to atrophic situations, although its effects on muscle atrophy induced by treatment with dexamethasone (DEX) are poorly known.The purpose of this study was to determine how long RT is required to promote preventive effects in flexor halluces longus (FHL) muscle atrophy induced by dexamethasone (DEX). After maximal voluntary carrying capacity (MVCC), 100 rats were separated in sedentary (SED) or resistance trained for 10 (RT10), 40 (RT40), 70 (RT70) and 100 (RT100) days. Groups were divided as control (CTRL) or treated with DEX. RT was performed with 80% of maximal voluntary carrying capacity (MVCC). During the last 10 days, the animals either received DEX (0.5 mg/kg/day, i.p.) or vehicle (saline, same volume as DEX treatment, i.p.). The FHL muscle was removed, cleaned, weighed and stored for determining the cross-sectional area, proteassomal activity 26s, and total p70S6K, p-p70S6KThr389, MuRF1, REDD1 and GAPDH protein level. The results arepresented as mean ± SEM. The repeated measures two-way analysis of variance (ANOVA) were used for food intake and, for further analysis,it was used two-way ANOVA, both with Tukey post hoc test and significance levelset as α<0.05. DEX reduced FHL mass (-26%), but RT70 and RT100 DEX groups presented atrophy attenuation. DEX reduced proteasome activity in SED (-33%) and RT70 (-44%) DEX. RT70 CTRL had increased proteasome activity when compared with RT10 and RT40 CTRL (+48% and +51%, respectively) groups and RT100 CTRL had reduced activity (-56%). DEX reduced phospho-p70S6KThr389/total p70S6k ratio in SED DEX (-24%), but it was reverted in RT10 (+48%) and RT70 DEX(+70%). RT70 CTRL presented higher values of this ratio than SED, RT40 and RT100 CTRL groups. DEX increased REDD1 (+47%) protein level only in SED DEX. MuRF-1 protein level increased in SED(+50%), RT10 (+45%) and RT40 (+46%)DEX groups, but it was blocked in RT70 and RT100 DEX groups. In summary, we suggest that DEX-induced FHL muscle atrophy requires at least 70 days of RT to be attenuated and this response involves a complete blockade of MuRF-1 and REDD1 protein level increase and the blockade phospho-p70S6KThr389/total p70S6k ratio reduction. Also, 100 days of RT did not promote any additional effects. It is interesting to note that only 10 days of RT evoked improvements in the synthesis pathway, which suggest that some molecular adjustments are required in early stages of skeletal muscle mass maintenance. / Os glicocorticoides sintéticos possuem potente ação anti-inflamatória e imunossupressora, entretanto seu uso crônico pode desencadear atrofia muscular. Por outro lado o treinamento resistido (TR) contrapõe-se a situações atróficas, embora seus efeitos sobre a atrofia muscular induzida pelo tratamento com dexametasona (DEX) são pouco conhecidos.O presente trabalho teve como objetivo verificar qual é o momento em que o efeito preventivo do TR (80% do carregamento máximo) é mais efetivo sobre a redução peso corporal e atrofia muscular induzidas pelo tratamento com DEX. Separamos 100 ratos Wistar machos em 10 grupos: sedentário controle (SED CTRL); sedentário tratado com DEX (SED DEX); treinado controle 10, 40, 70 e 100 dias (TR10 CTRL, TR40 CTRL, TR70 CTRL e TR100 CTRL) e treinado tratado com DEX 10, 40, 70 e 100 dias (TR10 DEX, TR40 DEX, TR70 DEX e TR100 DEX). Utilizamos o TR em escada (80% TCM). Nos 10 últimos dias os animais receberam DEX (0,5 mg/kg por dia, i.p.) ou o mesmo volume de salina. O músculo flexor longo do hálux (FHL) foi removido, limpo, pesado e armazenado para determinação da área de secção transversa, atividade do proteassoma 26s, e produção proteica dep70S6K total, p-p70S6KThr389, MuRF1, REDD1 e GAPDH. Os resultados são apresentados como média±EPM. Foi utilizada aanálise de variância de dois caminhos (ANOVA) para medidas repetidas para ingestão alimentar e para as variáveis restantes foi utilizada a ANOVA de dois caminhos. Na presença de interação, foi utilizado o posthoc de Tukey,com significância de α<0,05. A DEX reduziu 26% a massa muscular do FHL, mas o grupo TR70 e TR100 DEX apresentaram essa atrofia atenuada. O tratamento com DEX reduziu a atividade do proteassoma nos grupos SED (-33%) e TR70 DEX (-44%). O grupo TR70 CTRL teve sua atividade do proteassoma aumentada em relação aos grupos TR10 e TR40 CTRL (+48% e +51%, respectivamente), além do mais, o grupo TR100 CTRL teve sua atividade reduzida (-56%). A DEX reduziu a razão p-p70S6KThr389/p70S6k total no grupo SED DEX (-24%), mas essa resposta foi revertida no grupo TR10 (+48%) e TR70 (+70%) DEX. O grupo TR70 CTRL apresentou valores superiores dessa razão em relação aos grupos SED, TR40 e TR100 CTRL. A DEX aumentou a produção proteica de REDD1 (+47%) somente no grupo SED DEX. A produção proteica de MuRF1 foi aumentada nos grupos SED (+50%), TR10 (+45%) e TR40 (+46%) DEX, mas essa resposta foi completamente bloqueada nos grupos TR70 TR100 DEX. Com base nos resultados do presente estudo, pode-se sugerir que a atrofia muscular induzida por DEX no músculo FHL necessita de pelo menos 70 dias de TR para ser atenuada e essa resposta parece envolver o completo bloqueio dos aumentos de MuRF1 e REDD1, somados ao bloqueio da redução da razão p-p70S6KThr389/p70S6k. Além disso, 100 dias de TR não provocaram nenhum efeito preventivo adicional. É interessante notar que o TR, mesmo realizado por curto período (10 dias), promove melhorias na via de síntese de proteínas, oque sugere que alguns ajustes moleculares são necessários em estágios iniciais da manutenção da massa muscular. / CAPES: 1452526
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Le style emblématique des potières Iroquoiennes du Saint-Laurent : comparaison interrégionale de deux attributs identitairesLe Moine, Jean-Baptiste 04 1900 (has links)
No description available.
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Metody měření ve vesmíru / Methods of measuring in the UniverseKUČERA, Jan January 2017 (has links)
The work deals with distance measuring in space. The first part is about evolution of space arrangement and dimension imaginations from ancient times until the 20th century. Also Aristarchos´ heliocentric model of the solar system is described in detail, including his quantitative estimates of the Moon and Sun distances and dimensions. Hipparchos´ and Ptolemaios´ geometric models are described in detail too. Great attention is given to a genesis of heliocentric theory of Nicolaus Copernicus. The second part deals with contemporary methods of distance measuring. The work proceeds systematically from distances in the solar system to distances between stars as far as to distances between galaxies and quasars. It was necessary to write also about physical principles because distance measuring is based on them. The part of the work is a large pictorial supplement with text comments.
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Development of a double-sided ladder for tracking in high-energy physics / Développement d'une échelle double face pour la trajectométrie en physique des hautes énergiesBoitrelle, Benjamin 13 February 2017 (has links)
Le projet PLUME développe des échelles ultra-légères inspirées par le cahier des charges du détecteur de vertex pour le futur e+e- International Linear Collider (ILC). Nos travaux montrent que, pour une énergie de 350 GeV et une luminosité de 250 fb-1, l’ILC donnera accès à des états finals comme Hνν. Les modules PLUME exploitent le concept d’échelles double-face recouvertes de capteurs CMOS afin d’atteindre un budget de matière de 0,35 % en longueurs de radiation. Les tests effectués ont montré que les performances électriques des 12 capteurs intégrés sur ces échelles ne sont pas dégradées. La surface des échelles présente des déformations, mais nous avons mis au point un algorithme spécifique qui permet de corriger leurs effets lors du traitement des données. Finalement, une mesure de la longueur de radiation d’un prototype moins avancé a été réalisée avec un faisceau test au DESY. La valeur obtenue de 0,47±0,02 % en longueurs de radiation correspond au budget attendu. / The PLUME project develops ultra-light pixelated layers with specifications driven by the design of a vertex detector at the future e+e- International Linear Collider (ILC). The ILC will give access to final states like Hνν, as this work demonstrates for centre-of-mass energy 350GeV and a luminosity of 250 fb-1. PLUME devices exploit the concept of double-sided ladder spaved with thinned CMOS pixel sensors in order to reach a material budget of 0.35 % of radiation length. The present study validated that simultaneous operation of the 12 CMOS sensors integrated on such light ladders do not impact their electrical behaviour. Surface deformations were observed but a specific algorithm during the off- line analysis was proposed and successfully tested to preserve the native sensor spatial resolution. Finally, a measurement of the material budget of a less advanced ladder prototype has been performedat DESY test beam and yield 0.47±0.02 % of radiation length, matching the expected value.
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Algoritmos de aproximação de raízes quadradasCAMPOS, Danilo Albuquerque de 22 August 2014 (has links)
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Previous issue date: 2014-08-22 / In this work we are interested in showing three algorithms rational approximation of square roots by methods unknown or underutilized by teachers of elementary and secondary education. We begin by defining numerical sequence and convergence of sequences, will discuss the need to expand the concept of rational number and demonstrate the irrationality of the diagonal of a square. Prove an important theorem known in the literature as Dirichlet’s theorem and finally elencaremos three methods of approximating the square roots of natural non-perfect square numbers, very simple to be worked on in the classroom that are rational algorithm aproximção of Hiero of Alexandria, Theon’s Ladder and the Pell-Fermat equation, sende latter discursão fundamental to who will perform on the relationship of the three methods presented. / Neste trabalho estamos interessados em mostrar três algoritmos de aproximação racional de raízes quadradas por métodos pouco utilizados ou desconhecidos pelos professores do ensino fundamental e médio. Iniciaremos definindo sequência numérica e convergência de sequências, discutiremos sobre a necessidade de ampliação do conceito de número racional e demonstraremos a irracionalidade da diagonal de um quadrado. Provaremos um importante Teorema conhecido na literatura como o Teorema de Dirichlet, e por fim elencaremos três métodos de aproximação de raízes quadradas de números naturais não quadrados perfeitos, muito simples de serem trabalhados em sala de aula que são: O algoritmo de aproximação racional de Hierão de Alexandria, A escada de Theon e a Equação de Pell-Fermat, sendo este último fundamental para discussão que iremos realizar sobre a relação dos três métodos apresentados.
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Técnica experimental para quantificar a eficiência de distribuidores de líquidos industriais do tipo tubos perfurados paralelos. / Liquid aspersion effuciency quantification experiment: application in ladder type distributors.Marlene Silva de Moraes 07 July 2008 (has links)
O presente texto descreve um método experimental simples para comparar a eficiência de distribuidores de líquido empregados nas indústrias de tratamento de minérios em lavadores, classificadores e moinhos e nas indústrias de processos químicos. A técnica consiste basicamente em analisar a dispersão pelo desvio padrão da massa do líquido coletado em tubos verticais dispostos em arranjo quadrático colocados abaixo do distribuidor. Como exemplo de aplicação, empregouse para a coleta da massa de líquido uma unidade piloto, montada no Laboratório de Engenharia Química da Universidade Santa Cecília em Santos, com um banco de 21 tubos verticais de 52 mm de diâmetro interno e 800 mm de comprimento. Uma manta acrílica que não dispersa o líquido com 50 mm de espessura foi fixada entre o distribuidor e o banco de tubos para evitar respingos. Foram realizados ensaios com nove distribuidores do tipo espinha de peixe de 4 tubos paralelos cada, para uma coluna piloto com 400 mm de diâmetro. A literatura é discordante no que concerne aos parâmetros de projeto e eficiência destes distribuidores. Variaram-se o número (n) de orifícios (95, 127 e 159 furos/m2, 12, 16 e 20 furos por distribuidor) o diâmetro (d) dos orifícios (2, 3 e 4 mm) e as vazões de entrada indicadas por rotâmetro nos distribuidores (q) de 1,2; 1,4 e 1,6 m3/h. A melhor eficiência de espalhamento pelo menor desvio padrão (0,302) foi obtida com n de 159 furos/m2, d de 2 mm e q de 1,4 m3/h indicando as limitações dos parâmetros de projeto da literatura. A pressão (p), na entrada do distribuidor para esta condição, foi de apenas 0,51 kgf/cm2. A relação adimensional entre a área da seção do tubo de alimentação e a somatória da área dos furos foi de 5,81, a vazão volumétrica total por unidade de área da seção da coluna para esta melhor condição foi de 11,32 m3/(h.m2) e a velocidade média (v) em cada orifício foi de 6,31 m/s. Portanto, o método proposto permite comparar e quantificar a eficiência de distribuidores além de demonstrar a não validade de alguns parâmetros de projeto recomendados pela literatura. / The current text describes a simple experimental method in order to compare the efficiency of the liquid distributors applied at the ore treatment industries in washers, classifiers and mills as well as at the chemical processing industries. The technique basically consist of analyzing the dispersion through the standard deviation of the liquid mass which was collected in vertical pipes placed in a square way under the distributor. As an example of us usage, it has been applied a pilot scale for collecting the liquid mass, installed at the Santa Cecília Universitys Chemical Engineering Laboratory in Santos, with a setting of 21 vertical tubes measuring 52 mm in internal diameter and 800 mm in length. A 50 mm thick acrylic blanket was fixed between the distributor and the pipe setting in order to avoid splashes. Some experiments have been made with a ladder-tipe distributors containing 4 parallel tubes each, for a pilot column of 400 mm in diameter. The literature shows disagreement regarding the characteristics of the project and the efficiency of the distributors. The number of holes has varied (n) 95, 127 and 159 holes/m2; 12, 16 and 20 holes for distributor, the diameter of the holes (d) 2, 3 and 4 mm and the flow of entrance in the distributors (q) of 1,2; 1,4 and 1,6 m3/h. The best efficiency of splashing of the lowest deviation pattern (0,302) was achieved with n of 159 holes/m2, d of 2 mm and q of 1,4 m3/h showing the limitation of characteristics of the project literature. The pressure (p), for this condition in the distributor entrance, was only 0,51 kgf/cm2. The measuring relation between the area of the section of the feeding pipe and the addition of the area of the roles was 5,81, the total volume of the out flow for unit of the area of the column section for this better condition was 11,32 m3/(h m2) and the average speed (v), in each hole was 6,31 m/s. Finally, the indicated method permits the comparison and quantification of the efficiency of the distributors, besides showing that some of the project concepts are not valid and the literature does not recommend them.
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Efetividade da escada para peixes da UHE Engenheiro Sergio Motta - CESP para espécies de peixes migradoras neotropicais / Efetividade da escada para peixes da UHE Engenheiro Sergio Motta - CESP para espécies de peixes migradoras neotropicais / Effectiveness of the fish ladder Engenheiro Sergio Motta Hydroelectric Power Plant - CESP for neotropical migratory fish species / Effectiveness of the fish ladder Engenheiro Sergio Motta Hydroelectric Power Plant - CESP for neotropical migratory fish speciesWagner, Ricardo Luiz 21 December 2010 (has links)
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Previous issue date: 2010-12-21 / Transposition systems for fishes at the dam hydroelectric power plants are designed to mitigate impacts, however, it is necessary for these systems to be evaluated and monitored. This study, conducted at the fish ladder of the Engenheiro Sergio Motta Hydroelectric Power Plant - CESP, during the period from November 2009 to April 2010, aimed to analyze the effectiveness of this system, considering two aspects needed for analysis: the rate of attractiveness, and subsequently, the efficiency of the fish ladder. The rate of attractiveness considered the percentage of individuals who found the entry, while the efficiency was calculated from the percentage ascending along the fish ladder through the Ascend Function.
The Risk Function was used to identify sites that might hinder the ascent of the species studied. The RFID (Radio Frequency Identification) system was utilized in the study, with the installation of eight antennae along the fish ladder and transponders (PIT tags) of 32mm were implanted in four long-distance migratory fish species. We considered two sites for the release after the tagging: in the first, designated as the ramp, situated approximately 1,100m downstream the entrance to the fish ladder, 757 individuals were tagged, of which 151 were Brycon orbignyanus, 204 Piaractus mesopotamicus, 196 Prochilodus lineatus and 206 Rhinelepis aspera. At the second site, the pool 11 of the ladder, 317 individuals were tagged distributed in 100 P. mesopotamicus, 109 P. lineatus and 108 R. aspera. The results of the attractiveness for individuals released in the ramp were 15.89% for B. orbignyanus, 55.39% for P. mesopotamicus, 7.4% for P. lineatus and 24.73% for R. aspera. The results of the estimates of efficiency whith the use of the Ascend Function were differentiated for part of the species studied. For B. orbignyanus released in the ramp efficiency was 79%. P. mesopotamicus obtained 94% when released in the ramp, and 78% for the fishes released in the pool 11. The results for P. lineatus was 100% for the fishes released in the ramp and 69% for the pool 11. For the R. aspera percentages of 43 and 31% were observed in the ramp and in pool 11, respectively. Significant differences were verified between species regarding the time of arrival at the fish ladder: R. aspera (lowest time) differed from all the species and B. orbignyanus differed from P. mesopotamicus. The times spent traveling along the fish ladder were different for P. mesopotamicus and P. lineatus, with greater time accumulated by R. aspera. In the risk estimates, the highest values occurred in the initial portion, i.e., up the third antenna, suggesting that some hydrological variable may exist in this segment imposing greater restrictions upon the species studied. The assessments and monitoring of the effectiveness of the fish ladder in the Engenheiro Sergio Motta Hydroelectric Power Plant, for the species studied, as well as other target species, should be continued over the long term, in order to verify if this passage permits the fishes, within the reproductive period (piracema) to find and overcome the passage in good time to undertake their reproduction in the tributaries situated upstream of the dam. / Sistemas de transposição para peixes em barragens de hidrelétricas são projetados a fim de mitigar alguns impactos, no entanto, faz-se necessário a avaliação e monitoramento desses sistemas. Este estudo realizado na escada para peixes da UHE Engenheiro Sergio Motta CESP, no período de novembro/2009 a abril/2010, objetivou analisar a efetividade deste sistema, considerando dois aspectos necessários para análise: a taxa da atratividade e posteriormente, a eficiência da escada para peixes. Para o cálculo da atratividade foi considerada a porcentagem de indivíduos que encontraram a entrada e para a eficiência foi calculado o percentual de ascensão ao longo da escada para peixes, através da Função de Ascensão. A Função de Risco foi utilizada para identificar os locais que possam dificultar a ascensão das espécies estudadas. Foi utilizado o sistema de rádio freqüência (RFID Radio Frequency Identification) no estudo, com instalação de oito antenas ao longo da escada para peixes e transponders (PIT-tags) de 32mm foram implantados em quatro espécies de peixes migradores de longa distância. Foram considerados dois locais de soltura após a marcação: no primeiro, denominado rampa, aproximadamente 1.100m a jusante da entrada da escada, 757 indivíduos foram marcados, sendo 151 Brycon orbignyanus, 204 Piaractus mesopotamicus, 196 Prochilodus lineatus e 206 Rhinelepis aspera. E, no segundo local, o tanque 11 da escada, foram marcados 317 indivíduos distribuídos em 100 P. mesopotamicus, 109 P. lineatus e 108 R. aspera. Os resultados da atratividade para indivíduos liberados na rampa foram de 15,89% para B. orbignyanus, 55,39% para P. mesopotamicus, 7,4% para P. lineatus e de 24,73% para R. aspera. Os resultados das estimativas da eficiência, com uso da Função de Ascensão, foram diferenciados para parte das espécies estudadas. Para B. orbignyanus liberadas na rampa, a eficiência foi de 79%. P. mesopotamicus obteve 94%, quando liberados na rampa e 78% para os peixes liberados no tanque 11. Para P. lineatus resultou em 100% para os liberados na rampa e 69% para o tanque 11. Já para R. aspera percentagens de 43 e 31% foram observadas na rampa e tanque 11, respectivamente. Diferenças significativas foram constatadas quanto ao tempo de chegada à escada, entre as espécies: R. aspera (menor tempo) diferenciou de todas as espécies e B. orbignyanus foi distinta de P. mesopotamicus. Os tempos de deslocamento ao longo da escada foram diferentes para P. mesopotamicus e P. linetaus, com maior tempo acumulado para R. aspera. Para estimativas do risco, os valores mais elevados ocorreram na porção inicial, ou seja, até a terceira antena, sugerindo que nesse segmento possa haver alguma variável hidrológica que imponha maior restrição às espécies estudadas. As avaliações e monitoramento da efetividade da escada para peixes da UHE Engenheiro Sergio Motta para as espécies estudadas, bem como, as demais espécies alvo, devem ser continuadas, em longo prazo, com objetivo de verificar se esta passagem possibilita os peixes, no período reprodutivo (piracema), encontrarem e vencerem a passagem em tempo hábil, para realizarem a reprodução nos tributários existentes a montante da barragem.
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Contrer l'attaque Simple Power Analysis efficacement dans les applications de la cryptographie asymétrique, algorithmes et implantations / Thwart simple power analysis efficiently in asymmetric cryptographic applications, algorithms and implementationsRobert, Jean-Marc 08 December 2015 (has links)
Avec le développement des communications et de l'Internet, l'échange des informations cryptées a explosé. Cette évolution a été possible par le développement des protocoles de la cryptographie asymétrique qui font appel à des opérations arithmétiques telles que l'exponentiation modulaire sur des grands entiers ou la multiplication scalaire de point de courbe elliptique. Ces calculs sont réalisés par des plates-formes diverses, depuis la carte à puce jusqu'aux serveurs les plus puissants. Ces plates-formes font l'objet d'attaques qui exploitent les informations recueillies par un canal auxiliaire, tels que le courant instantané consommé ou le rayonnement électromagnétique émis par la plate-forme en fonctionnement.Dans la thèse, nous améliorons les performances des opérations résistantes à l'attaque Simple Power Analysis. Sur l'exponentiation modulaire, nous proposons d'améliorer les performances par l'utilisation de multiplications modulaires multiples avec une opérande commune optimisées. Nous avons proposé trois améliorations sur la multiplication scalaire de point de courbe elliptique : sur corps binaire, nous employons des améliorations sur les opérations combinées AB,AC et AB+CD sur les approches Double-and-add, Halve-and-add et Double/halve-and-add et l'échelle binaire de Montgomery ; sur corps binaire, nous proposons de paralléliser l'échelle binaire de Montgomery ; nous réalisons l'implantation d'une approche parallèle de l'approche Right-to-left Double-and-add sur corps premier et binaire, Halve-and-add et Double/halve-and-add sur corps binaire. / The development of online communications and the Internet have made encrypted data exchange fast growing. This has been possible with the development of asymmetric cryptographic protocols, which make use of arithmetic computations such as modular exponentiation of large integer or elliptic curve scalar multiplication. These computations are performed by various platforms, including smart-cards as well as large and powerful servers. The platforms are subject to attacks taking advantage of information leaked through side channels, such as instantaneous power consumption or electromagnetic radiations.In this thesis, we improve the performance of cryptographic computations resistant to Simple Power Analysis. On modular exponentiation, we propose to use multiple multiplications sharing a common operand to achieve this goal. On elliptic curve scalar multiplication, we suggest three different improvements : over binary fields, we make use of improved combined operation AB,AC and AB+CD applied to Double-and-add, Halve-and-add and Double/halve-and-add approaches, and to the Montgomery ladder ; over binary field, we propose a parallel Montgomery ladder ; we make an implementation of a parallel approach based on the Right-to-left Double-and-add algorithm over binary and prime fields, and extend this implementation to the Halve-and-add and Double/halve-and-add over binary fields.
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Le tapis roulant à échelle comme nouvel outil d'étude de la locomotion, chez les rats intacts et suite à une lésion corticale.Perraud, Blanche 01 1900 (has links)
No description available.
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