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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
191

Разработка девелоперского проекта многофункциональной торговой недвижимости в городе Екатеринбург : магистерская диссертация / Development of a development project of multifunctional commercial real estate in Yekaterinburg

Копылова, О. В., Kopylova, O. V. January 2019 (has links)
Магистерская диссертация состоит из введения, трех глав, заключения, списка литературы и приложения. Рассмотрены основные понятия и классификация торговых комплексов, тенденции развития общественных пространств, включая доисторические периоды времени, и приведён отечественный и зарубежный опыты в организации общественных пространств. Изучена макроэкономическая ситуация в Российской Федерации и регионе Свердловской области, разработана концепция многофункционального торгово-развлекательного комплекса, исследовано количество населения и мигрантов по возрастным и гендерным категориям. Рассчитана стоимость строительства данного многофункционального торгово-развлекательного комплекса на каждом этапе строительства, определена необходимая документация и проанализирована будущая экономическая эффективность данного комплекса. В заключении сформулированы основные выводы и результаты диссертационного исследования. / The master's thesis consists of an introduction, three chapters, a conclusion, a list of references and an Appendix. The main concepts and classification of shopping complexes, trends in the development of public spaces, including prehistoric periods of time, are considered, and domestic and foreign experiences in the organization of public spaces are given. The macroeconomic situation in the Russian Federation and the Sverdlovsk region was studied, the concept of a multifunctional shopping and entertainment complex was developed, the number of population and migrants by age and gender categories was studied. The cost of construction of this multifunctional shopping and entertainment complex at each stage of construction is calculated, the necessary documentation is determined and the future economic efficiency of this complex is analyzed. In conclusion, the main conclusions and results of the dissertation research are formulated.
192

Финансово-экономическое обоснование девелоперского проекта по строительству многофункционального комплекса в микрорайоне Солнечный : магистерская диссертация / Financial and economic justification of the development project for the construction of a multifunctional complex in the Solnechny microdistrict

Гельвих, Т. Р., Gelvich, T. R. January 2022 (has links)
Выпускная квалификационная работа (магистерская диссертация) состоит из введения, трех глав, заключения, библиографического списка, включающего 62 наименования. Работа включает 19 таблиц и 52 рисунков. Общий объем Выпускной квалификационной работы (магистерской диссертации) – 95 страницы. Проработан российский и зарубежный научно-практический опыт строительства и проектирования многофункциональных комплексов. Проведен анализ района расположения объекта строительства МФК в микрорайоне (далее – мкр) Солнечный в г. Екатеринбург. Разработано финансово-экономическое обоснование девелоперского проекта по строительству многофункционального комплекса по адресу Свердловская область, г. Екатеринбург, мкр Солнечный, ул. Чемпионов. / The final qualifying work (master's thesis) consists of an introduction, three chapters, a conclusion, a bibliographic list including 62 titles. The work includes 19 tables and 52 figures. The total volume of the Final qualifying work (master's thesis) is 95 pages. The Russian and foreign scientific and practical experience of construction and design of multifunctional complexes has been worked out. The analysis of the location of the IFC construction facility in the microdistrict (hereinafter – the MD) is carried out Sunny in Yekaterinburg. The financial and economic justification of the development project for the construction of a multifunctional complex at the address Sverdlovsk region, Yekaterinburg, Solnechny MKR, Champions Street has been developed.
193

Konzeption und Entwurf eines strukturellen Energiespeichers für Anwendungen in der Luft- und Raumfahrt

Kahlmeyer, Gabriel 18 October 2023 (has links)
Die Energieversorgung unbemannter Flugobjekte (UAV) erfolgt gegenwärtig über Batterie-Module. Diese sind als zusätzliche Bauteile in die Struktur eingebracht. Daher erhöht sich das Gesamtgewicht der Struktur deutlich. Im Sinne der Energiespeicherung existieren verschiedene multifunktionale Konzeptansätze. Hierunter zählen strukturelle, elektrische Energiespeicherungssysteme (SEES). Bei diesen Konzepten erfolgt die Energiespeicherung in den Bauteilen bei gleichzeitiger Erfüllung struktureller Eigenschaften. Somit gelten diese als masselose Energiespeicherungssysteme. Im Rahmen dieser Thesis erfolgt eine Betrachtung verschiedener SEES. Schließlich werden strukturelle Superkondensatoren (SSC) zur Integration in ein UAV ausgewählt. Als Integrationsobjekt dient die Drohne DJI Matrice 600 Pro. Ein SSC mit besten Eigenschaften wird anhand einer systematischen Methode aus der aktuellen Literatur ermittelt. Dieser Favorit wird konzeptionell in die Drohne integriert. Diesbezüglich erfolgen verschiedene, physikalische Berechnungen zu elektrischen Eigenschaften und anliegenden Kräften, sodass Rückschlüsse zur Leistungsfähigkeit getroffen werden können. Im weiteren Verlauf wird eine Mehrkörpersimulation mit der Finite-Elemente-Methode (FEM) am Untersuchungsobjekt durchgeführt. Mit der Kenntnis über die anliegenden Beanspruchungen erfolgt weiterführend eine detailgetreue, strukturmechanische Analyse des SSC unter Verwendung der FEM an repräsentativen Volumenelementen. Fortan wird das multiphysikalische Kopplungsphänomen im strukturellen Elektrolyten simuliert. Hierfür werden mathematische Abhängigkeiten von mechanischen Einwirkungen auf geometrisch, veränderliche Größen ermittelt. Diese werden in eine elektrochemische Simulation überführt, sodass das multiphysikalische Kopplungsphänomen berechnet wird. Als Ergebnis zeigt sich, dass die Kompression des Elektrolyten negative Auswirkungen auf die elektrochemischen Eigenschaften hat...:Symbol- und Abkürzungsverzeichnis Abbildungsverzeichnis Tabellenverzeichnis 1 Einleitung 2 Grundlagen 2.1 Strukturelle elektrische Energiespeicherungssysteme 2.2 Superkondensatoren – Aufbau und Funktionsweise 2.3 Berechnungsgrößen am strukturellen Superkondensator 3 Stand der Forschung 3.1 Literaturrecherche – Strukturelle Superkondensatoren 3.2 Festlegung von Parametern und Auswahl des SSC 4 Anwendungsfall: DJI Matrice 600 Pro 4.1 Produktanalyse DJI Matrice 600 Pro 4.2 Integration des strukturellen Superkondensators in die Struktur 4.3 Berechnung elektrischer Eigenschaften 4.4 Analyse und Berechnung der wirkenden Kräfte 4.5 FEM-Mehrkörpersimulation am UAV-Anwendungsfall 5 Strukturmechanische Simulation am SSC 5.1 SSC-Bereichsanalyse und Simulationsaufgabe 5.2 Repräsentative Volumenelemente und Einheitszelle 5.3 Simulation Bereich 1: Poröse Faser in der Matrix 5.4 Simulation Bereich 2: Fasern in der Matrix 5.5 Simulation Bereich 3: Poröser Elektrolyt 6 Multiphysikalische SSC-Simulation 6.1 Multiphysikalischer Kopplungseffekt 6.2 Analyse der geometrischen Größen Porosität und Tortuosität 6.3 Multiphysikalische Simulation mit COMSOL Multiphysics Zusammenfassung und Ausblick Literatur / Unmanned aerial vehicles (UAV) are currently powered by batteries, which are integrated as additional components within their structure. However, the substantial weight of these batteries leads to increased energy consumption and reduced flight time. In addition to battery-based energy systems, there are alternative concepts that serve multifunctional roles. Structural electrical energy storage systems (SEES) for example carry loads and offer electrical energy storage functions at the same time. In this work, structural Supercapacitors (SSC) are selected as SEES candidates. A systematic approach is employed to integrate an SSC into the DJI Matrice 600 Pro done as an UAV use case. The efficiency of the integrated system is assessed through various physical calculations. Subsequently, a multi-body simulation using the finite element method is conducted on the chosen UAV model. Furthermore, representative volume elements are defined within the structural supercapacitor, and simulations are performed to comprehend the underlying processes. During the exploration of multiphysical coupling effects between mechanical stresses and electrochemical behaviors, certain geometric parameters are identified as influential factors. Regression analysis is employed to formulate mathematical equations representing these dependencies for simulation purposes. A multiphysical simulation is executed, considering compression as a representative load case. The results are evaluated using cyclic voltammetry. The study concludes that mechanical compression loads have an adverse effect on the electrochemical properties of the structural supercapacitor:Symbol- und Abkürzungsverzeichnis Abbildungsverzeichnis Tabellenverzeichnis 1 Einleitung 2 Grundlagen 2.1 Strukturelle elektrische Energiespeicherungssysteme 2.2 Superkondensatoren – Aufbau und Funktionsweise 2.3 Berechnungsgrößen am strukturellen Superkondensator 3 Stand der Forschung 3.1 Literaturrecherche – Strukturelle Superkondensatoren 3.2 Festlegung von Parametern und Auswahl des SSC 4 Anwendungsfall: DJI Matrice 600 Pro 4.1 Produktanalyse DJI Matrice 600 Pro 4.2 Integration des strukturellen Superkondensators in die Struktur 4.3 Berechnung elektrischer Eigenschaften 4.4 Analyse und Berechnung der wirkenden Kräfte 4.5 FEM-Mehrkörpersimulation am UAV-Anwendungsfall 5 Strukturmechanische Simulation am SSC 5.1 SSC-Bereichsanalyse und Simulationsaufgabe 5.2 Repräsentative Volumenelemente und Einheitszelle 5.3 Simulation Bereich 1: Poröse Faser in der Matrix 5.4 Simulation Bereich 2: Fasern in der Matrix 5.5 Simulation Bereich 3: Poröser Elektrolyt 6 Multiphysikalische SSC-Simulation 6.1 Multiphysikalischer Kopplungseffekt 6.2 Analyse der geometrischen Größen Porosität und Tortuosität 6.3 Multiphysikalische Simulation mit COMSOL Multiphysics Zusammenfassung und Ausblick Literatur
194

Microwave Lens Designs: Optimization, Fast Simulation Algorithms, and 360-Degree Scanning Techniques

Dong, Junwei 30 October 2009 (has links)
Microwave lenses support low-phase error, wideband, wide-angle scanning, and true-time delay (TTD) beam forming. They provide ideal performance for applications such as satellites, remote-piloted vehicles, collision-avoidance radars and ultra-wideband communications systems. The emerging printed lenses in recent years have facilitated the advancement of designing high performance but low-profile, light-weight, and small-size beam-forming networks (BFNs). The microwave lens adopts a few beam ports to illuminate the prescribed receiving ports that feed energy into radiating antennas. Multi-beam patterns can be achieved by exciting multiple beam ports at a time. The design process starts with path-length equations from a limited number of beam-port foci assumptions. This constraint does not take into account the amplitude information; however, it allows an initial lens geometry to be solved. The resulted scanning angle of microwave lens is limited by the beam port contour, as such ± 90 degrees. In this dissertation, three contributions are made from the aspects of minimized phase errors, accurate and efficient simulation algorithms, and 360-degree scanning range extension. First, a minimum-phase-error, non-focal lens design method is proposed. It does not require a specific number of foci along the beam contour; however, minimum phase errors for all beam ports are able to be achieved. The proposed method takes into account flexible prescribed geometrical design parameters, and adopts numerical optimization algorithms to perform phase error minimization. Numerical results compared with the published tri-focal and quadru-focal lenses demonstrate the merits of the proposed method. Second, an accurate and fast simulation method for the microwave lens has been developed to predict the phase, amplitude, array factor, and power efficiency performance. The proposed method is compared to both full-wave simulation and measurement. Comparable results have been achieved. Third, a novel method for a 360-degree scanning microwave lens is proposed. This concept uses the beam ports and the receive ports in an interleaving sequence such that adjacent ports alternate beam and receive functions. The result is a lens that produces scanned beams on opposite sides of the structure resulting in a 360-degree scanning range. The structure can use multiple opposing facets or continuous circular-port and radiating-element contours. To prove the concept, a four-facet microstrip lens has been designed, simulated, fabricated, and tested. The comparison between full-wave simulation and measurement has demonstrated good agreement. / Ph. D.
195

Från toppen till botten och tillbaka : Om utformningen av ett användarvänligt multifunktionellt behandlingsrum

Bodin, Linnea January 2016 (has links)
Detta examensarbete är en studie i hur ett multifunktionellt behandlingsrum kan utformas. I behandlingsrummet ska det finnas möjligheter att utföra ett flertal olika aktiviteter, och det ska vara smidigt att skifta mellan dessa. Målsättningen har varit att skapa goda förutsättningar för att utföra rehabiliteringsaktiviteter, genom att underlätta terapeuternas arbete men också kundernas möjlighet att tillgodogöra sig behandlingen.   Arbetet har utgått från ett FMT- behandlingscenters lokaler i Eskilstuna. De har bland annat efterfrågat en gestaltning som hjälper till att reducera ljud, och optimera ljusförhållanden.   Studien har baserats på teorier om färg, ljus, akustik, ergonomi, designprinciper och gestaltlagar. I arbetet har följande metoder utförts: intervju, platsanalys, observation och introspektion. Behandlingsrummet har blivit mer avskalat i och med den avskärmning som blivit nyckeln i denna flexibla lösning. / This is a study on how to design multi-functional treatment rooms. In this case the particular treatment room must support the possibility to perform a variety of activities, and it should be easy to switch between those. The goal is to provide favorable conditions to carry out rehabilitation, by facilitating the therapists' work, but also the customers’ ability to benefit from the treatment. This work has developed out of a FMT treatment centers premises in Eskilstuna. The request was a design that could help to reduce noise and optimize lighting conditions, this has also been the main focus for the choice of spatial elements that are included in the design. The study is based on the theories on color, light, acoustics, ergonomics, design principles and gestalt psychology. Methods in use were: interview, site analysis, observation and introspection. The treatment room has become more uncluttered thanks to the foreclosure that became a key in the new a key in this flexible design.
196

Multifunctional Carbon Foams by Emulsion Templating : Synthesis, Microstructure, and 3D Li-ion Microbatteries

Asfaw, Habtom Desta January 2017 (has links)
Carbon foams are among the existing electrode designs proposed for use in 3D Li-ion microbatteries. For such electrodes to find applications in practical microbatteries, however, their void sizes, specific surface areas and pore volumes need be optimized. This thesis concerns the synthesis of highly porous carbon foams and their multifunctional applications in 3D microbatteries. The carbon foams are derived from polymers that are obtained by polymerizing high internal phase water-in-oil emulsions (HIPEs). In general, the carbonization of the sulfonated polymers yielded hierarchically porous structures with void sizes ranging from 2 to 35 µm and a BET specific surface area as high as 630 m2 g-1. Thermogravimetric and spectroscopic evidence indicated that the sulfonic acid groups, introduced during sulfonation, transformed above 250 oC to thioether (-C-S-) crosslinks which were responsible for the thermal stability and charring tendency of the polymer precursors. Depending on the preparation of the HIPEs, the specific surface areas and void-size distributions were observed to vary considerably. In addition, the pyrolysis temperature could also affect the microstructures, the degree of graphitization, and the surface chemistry of the carbon foams. Various potential applications were explored for the bespoke carbon foams. First, their use as freestanding active materials in 3D microbatteries was studied. The carbon foams obtained at 700 to 1500 oC suffered from significant irreversible capacity loss during the initial discharge. In an effort to alleviate this drawback, the pyrolysis temperature was raised to 2200 oC. The resulting carbon foams were observed to deliver high, stable areal capacities over several cycles. Secondly, the possibility of using these structures as 3D current collectors for various active materials was investigated in-depth. As a proof-of-concept demonstration, positive active materials like polyaniline and LiFePO4 were deposited on the 3D architectures by means of electrodeposition and sol-gel approach, respectively. In both cases, the composite electrodes exhibited reasonably high cyclability and rate performance at different current densities. The syntheses of niobium and molybdenum oxides and their potential application as electrodes in microbatteries were also studied. In such applications, the carbon foams served dual purposes as 3D scaffolds and as reducing reactants in the carbothermal reduction process. Finally, a facile method of coating carbon substrates with oxide nanosheets was developed. The approach involved the exfoliation of crystalline VO2 to prepare dispersions of hydrated V2O5, which were subsequently cast onto CNT paper to form oxide films of different thicknesses.
197

Permeabilidade espacial e zelo urbanístico no projeto arquitetônico: da modernidade à pós modernidade nos edifícios multifuncionais do eixo estrutural sul de Curitiba, 1966-2008 / Spacial permeability and urban care in architectural design: from modernity to post-modernity in multifunctionals buildings located on the southern structural axis of Curitiba

Dziura, Giselle Luzia 01 July 2009 (has links)
O estudo consiste na análise das mudanças da relação espacial do edifício multifuncional, caracterizado pelo Plano Massa, com o ambiente urbano marcado pelo Eixo Estrutural Sul em Curitiba, entre 1966 e 2008.O Plano Massa consisteemuma configuração arquitetônica e urbanística que atende a orientações legais específicas de ocupação nos Eixos Estruturais. Estes são resultantes de uma das propostas do Plano Preliminar de Urbanismo, de 1965, e caracterizam-se como setores em faixa submetidos a diretrizes de ocupação e uso do solo, fundamentadas no crescimento e adensamento, e condutores da expansão da cidade em vias tangenciais ao centro desta. A relação espacial edifício/entorno imediato incide na transição entre espaço público, presente nas galerias cobertas, e semipúblico, no interior dos edifícios, cujo processo de transformação urbana se sustenta no processo de migração deformada. A migração constitui a transição, em diferentes graus de dimensão física, social e funcional, dos espaços públicos para o interior dos edifícios. Atribui-se a deformação à mudança do caráter de uso e apropriação e, conseqüentemente, do significado: de espaço público para semipúblico. Assim, a hipótese principal é que, com a tensão entre as forças das regras do planejamento urbano, as exigências do mercado imobiliário e as mudanças sociais, econômicas e culturais, houve uma tendência de redução na utilização dos espaços públicos por pedestres, aliada à migração deformada desses espaços para o interior dos edifícios multifuncionais no trecho e período descritos. O objetivo do trabalho consiste em avançar na reflexão histórica e teórica sobre esses edifícios e sua inter-relação com o espaço urbano, a fim de fornecer subsídios para o ensino da arquitetura e urbanismo e desenvolver projetos nessa área em contextos similares. A partir da análise conjuntural de cenários, identificam-se três momentos em que ocorreram tais transformações urbanas. O primeiro (1966-1971) se refere aos Eixos Estruturais como concepção, com o anseio de planejar conforme o pensamento modernista, cujo Plano Diretor atendia à legislação específica. O segundo (1971-1983) compreende o Plano Massa perante o planejamento, com redefinição do pensamento moderno quanto à implantação e ocupação dos edifícios. O terceiro (1983-2008) inclui a adaptação dessas regras aos interesses políticos e imobiliários e às transformações ocorridas na produção do espaço urbano, cujo resultado tendeu à migração mencionada. Para atingir o objetivo proposto e comprovar a hipótese levantada, os procedimentos metodológicos consistem no levantamento de obras construídas, seguido pela identificação das tipologias conforme seu ano de implantação, e pela análise da migração deformada dos espaços quanto à permanência e aparecimento ou desaparecimento das tipologias identificadas, usando como parâmetro a permeabilidade espacial. Os períodos históricos buscam explicar as mudanças entre a teoria moderna e a prática pós-moderna. Assim, a análise pretende esclarecer alguns princípios da Pós-Modernidade que podem ser observados no trecho estudado determinados pelo advento do consumismo, aperfeiçoamento do lar para socialização, encapsulamento das trocas comerciais nos corredores protegidos das galerias e necessidade de segurança física, entre outros responsáveis pelo amadurecimento de uma cultura urbana, e forjados por vários atores sociais. / The study is the analysis of spatial changes of the multifunctional building, characterized by the Plano Massa with the urban environment marked by the Southern Strutural Axis in Curitiba, between 1966 and 2008. The Plano Massa consists in an architectural and urbanistic configuration built according the guidelines of specific legal occupation in the structural axis, which were first defined on the \"Preliminary Master Plan\" in 1965. Their definition characterized the city´s growth as linear, following specific land use, transportation and road system guidelines. The linear corridors conduct the city expansion, tangential to the city center. The building/neighborhood spatial relation affects the transition between public spaces as the covered galleries, and semi-public, as inside the buildings in which the process of urban transformation is found on the deformed migration process. Migration is the transition, with a variety of physical, social and functional degrees, from public spaces into the interior of the buildings. Deformation corresponds to the changes of use, caused by the ownership and consequently the change of the building´s meaning from a public space to a semi-public space. Therefore, the main hypothesis is, with the tension among the forces of urban planning rules, the requirements of the property market and social changes, economic and cultural, there was a trend in reducing the use of public spaces for pedestrians, added to the deformed migration to inside the multifunctional buildings, in the Southern Strutural Axis in Curitiba during the period of analisys. The objective is to advance the historical and theoretical reflection on these buildings and their inter-relationship with the urban space in order to provide support for teaching architecture and urban design and developing projects in this area in similar contexts. From the analysis of economic scenarios, there are identified three moments that these urban transformations have occurred. The first one (1966-1971) refers to the Structural Axis as a design concept, inspired on the modernist mind set when the Master Plan met the specific legislation. The second period (1971-1983) includes the Plano Massa to the planning, with redefinition of the modern thought by the establishment of the buildings occupation. The third period (1983-2008) includes the adaptation of these rules to the political and property market and the changes in the production of urban space as the result of the migration mentioned. To achieve the proposed objective and to prove the hypothesis, the methodological procedures are: the organization of the data from the buildings constructed, followed by the identification of the buildings´ typology by the year of their development, and the analysis of deformed migration spaces by the appearance or disappearance of the types identified, using the spacial permeability as a parameter. The historical periods seek to explain the changes between modern theory and postmodern practice. Thus, the analysis seeks to clarify certain principles of post-modernity that can be observed in the studied cases, determined by the advent of consumerism, the home improvement for socialization, the commerce encapsulation inside the corridors and protected galleries, as a physical security, and some other responsible features as the urban culture enrichment, developed by various social actors.
198

Thérapies par rayonnements appliquées au cas du glioblastome : intérêt du suivi par spectroscopie et imagerie de diffusion par résonance magnétique : vers une thérapie bimodale / Radiation therapies for glioblastoma : Interest of post-treatment monitoring with magnetic resonance diffusion imaging and spectroscopy : Towards a bimodal therapy

Toussaint, Magali 15 November 2016 (has links)
Les limitations rencontrées aujourd'hui dans le traitement du glioblastome (GBM) concernent notamment la qualité de l'exérèse dont dépend le pronostic et le manque de contrôle local de la croissance tumorale, sachant que les récidives apparaissent dans plus de 80% des cas dans le volume cible de radiothérapie. Dans ce contexte, la thérapie photodynamique interstitielle (iPDT) se présente comme un outil complémentaire prometteur qui permettrait d'améliorer le contrôle local de la tumeur. La première partie de ce travail de thèse a porté sur le suivi longitudinal par Imagerie par Résonance Magnétique (IRM) de la réponse tumorale post-iPDT sur un modèle de rat nude xenogreffé en orthotopique par un modèle de GBM humain. Le suivi par IRM et Spectroscopie par Résonance Magnétique (SRM) a fourni des indicateurs précoces de l'efficacité du traitement, permettant de discriminer dès un jour post-iPDT les animaux répondeurs des non-répondeurs. Cependant, une des limitations de la PDT, demeure la faible profondeur de pénétration de la lumière visible utilisée pour activer le photosensibilisateur et induire les réactions de photo-oxydations. La seconde partie de ce travail a porté sur l'évaluation d'un nouveau concept appelé "PDTX" permettant de coupler l'effet photodynamique à celui de la radiothérapie pour une radiothérapie photodynamique, en jouant notamment sur la complémentarité des espèces réactives de l'oxygène générées et des effets RX-induits. Pour cela, nous avons validé l'intérêt d'une nanoparticule hybride de type AGuIX® composée de terbium et de porphyrine, le terbium étant le scintillateur capable d'être excité par les rayons X et d'émettre des photons à une longueur d'onde appropriée pour activer le photosensibilisateur. Le transfert d'énergie par FRET (Förster Resonance Energy Transfer) entre le terbium et la porphyrine a été mis en exergue. Les résultats in vitro démontrent le potentiel thérapeutique de ce nouveau nano-objet à basse énergie / The limitations encountered today in the treatment of glioblastoma (GBM) involve the quality of the resection on which depends prognosis and the lack of local control of the tumor, knowing that relapses occur in 80% of cases in the radiotherapy target tumor volume. In this context, interstitial photodynamic therapy (iPDT) is a promising additional tool that would allow to improve local control of the tumor. The first part of this thesis focused on the longitudinal follow-up by Magnetic Resonance Imaging (MRI) of the post-iPDT tumor response in a nude rat model of orthotopic xenograft of human GBM cell line. MRI and Magnetic Resonance Spectroscopy (MRS) monitoring provided early indicators of the effectiveness of treatment, for discriminate from one day post-IPDT non-responders from responders animals. However, one of the limitations of PDT remains the low penetration of visible light used to activate the photosensitizer and induce reactions of photo-oxidation. This is why the second part of this research focused on the evaluation of a new concept called "PDTX" for coupling the photodynamic effect with radiotherapy effect for a photodynamic radiotherapy, playing especially on the complementarity of reactive species of oxygen generated and RX-induced effects. For this, we validated the interest of an AGuIX®-type hybrid nanoparticle composed of terbium and porphyrin, terbium being the scintillator capable of being excited by X-rays and emits photons at an appropriate wavelength in order to activate the photosensitizer. The energy transfer FRET (Förster Resonance Energy Transfer) between terbium and porphyrin was highlighted. In vitro results demonstrate the therapeutic potential of this new nano-object at low-energy
199

Salas de recursos multifuncionais: a interação entre família e escola no Município de Matelândia - Paraná / Multifunctional classrooms: the interaction between family and school in Matelândia – Paraná

Silva, Josiane Marcela Andrade 29 August 2018 (has links)
Submitted by Marilene Donadel (marilene.donadel@unioeste.br) on 2019-01-22T18:20:46Z No. of bitstreams: 1 Josiane_Silva_2018.pdf: 3009818 bytes, checksum: f9c61321e1806d03d05ddd71a0972177 (MD5) / Made available in DSpace on 2019-01-22T18:20:46Z (GMT). No. of bitstreams: 1 Josiane_Silva_2018.pdf: 3009818 bytes, checksum: f9c61321e1806d03d05ddd71a0972177 (MD5) Previous issue date: 2018-08-29 / This research aims to understand and analyze if there is a participation and also the way it occurs the family interaction in education policy, specifity of multifunctional classes which help the special education students in the perspective of inclusive education at the public education network in Matelândia – Paraná. In order to reaching the study objective, there were specific goals: Identify the family engagement and comprehension about the learning disability of the child; Understand the performance of the inclusive education policy worldwide and in Matelândia-PR; Check the teachers’ understanding about the family interaction to the student learning process; Apprehend the conception of inclusive education in the current legislation which implant the multifunctional classes; Comprehend and discuss the family into the inclusive education policy. In this regard, the question which directed the investigation was this one: In the face of the child educational needs of the target audience in the national policy of special education and the inclusive education perspective, how does the interaction between school and family happen? That way, it was necessary specific methodological procedures, defining it as qualitative, descriptive and exploratory research.During the documental research, they prioritized the federal, state and city legislation which treat about inclusive education.The bibliography subsidized a debate about the social policies and among them, the educational policy in the inclusive perspective and the family in the context of the social policies. The field researchcontemplated nine individuals, and among them, commom teachers, special education students’ families and multifunctional class teachers. The current investigation looks back the history of assisting people with disabilities in Brazil, special education progress to the inclusive perspective and also social policies in the specifity of education and family participation. On the basis of this study, it can be stated that there are weaknesses in the interaction among family, school and professionals who assist people with disabilities, development disordersand high levelskills. The main result of the researchwas the occurrence of communication between school and family, but not as desired, it needs to be improved. It will also be necessary to build strategies with the family and school in order to ease reliable and friendly environment for the children, the members of the family and the education professionals. / Essa pesquisa objetiva compreender e analisar se ocorre a participação e o modo como acontece a interação da família na Política de educação, na especificidade das Salas de Recursos Multifuncionais que atendem aos alunos da Educação Especial na Perspectiva da Educação Inclusiva na rede de ensino pública do Município de Matelândia-Paraná. Para dar conta de atingir o proposto na pesquisa, elencou-se como objetivos específicos: Identificar o envolvimento da família e entendimento da família sobre a dificuldade de aprendizagem da criança; compreender a execução da Política de Educação Inclusiva em nível, mundial, nacional e municipal em Matelândia – PR; verificar o entendimento dos professores de salas de recursos multifuncionais e de sala comum sobre a interação da família para a aprendizagem dos alunos; apreender a concepção de educação inclusiva na legislação vigente que implanta as salas de recursos multifuncionais; compreender e discutir a família na política educacional inclusiva. Com este propósito, a questão que direcionou a investigação foi a seguinte: Diante das necessidades educacionais da criança do público alvo da Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva como ocorre a interação entre escola e família? Nesse sentido, recorreu-se a determinados procedimentos metodológicos definindo-se a pesquisa qualitativa, descritiva e exploratória. Na investigação documental, foram priorizadas as legislações Federais, Estaduais e Municipais, que tratam da Educação Inclusiva. A bibliografia subsidiou o debate sobre as políticas sociais, dentre elas a política de educação na perspectiva inclusiva e família no contexto das políticas sociais. Quanto à pesquisa de campo realizada, contemplou nove sujeitos entre eles, professores de sala comum, famílias de alunos público alvo da educação especial na perspectiva inclusiva e professores de Salas de Recursos Multifuncionais. A presente investigação percorreu a história de atendimento às pessoas com deficiência no Brasil, sobre os avanços da educação especial para a educação especial na perspectiva inclusiva, como também sobre a política social na especificidade da Educação e a participação da família. Com base no estudo desenvolvido, pode-se afirmar que a interação entre a família, a escola e os profissionais que atendem estudantes com deficiência, transtornos globais do desenvolvimento e altas habilidades/superdotação possui fragilidades. A investigação apresentou como resultado principal que ocorre a comunicação entre as instituições família e escola, mas não a desejada sendo uma questão a se avançar. Por fim, para que os objetivos em torno dos alunos sejam alcançados será necessário construir estratégias conjuntas entre família e escola de forma que favoreçam e possibilitem ambientes acolhedores e confiáveis, tanto para as crianças como para os membros das famílias e os profissionais de educação.
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Professores de salas de recursos multifuncionais: vivências de prazer e sofrimento no contexto de trabalho

Macedo, Edilson Barros de 27 November 2017 (has links)
No Brasil, a construção de políticas públicas voltadas para pessoas com necessidades educacionais especiais teve inicio ainda no final do século XIX, período em se que criou, com base em experiências europeias, as primeiras instituições com objetivo de atender àqueles que na época apresentavam alguma deficiência auditiva, visual e física. Foi somente nos anos 50 e 60 que verdadeiramente se inicia a construção de serviços mais contemplativos e coerentes com as necessidades da população brasileira. Assim sendo, surge o chamado atendimento educacional especializado que dentre seus diversos serviços existe a sala de recurso multifuncional, espaço localizado na escola onde se oferta o atendimento educacional especializado aos discentes com necessidades educacionais especiais. Neste contexto, a presente pesquisa, de natureza qualitativa, exploratória e descritiva, teve por objetivos identificar as principais vivências de prazer e sofrimento dos professores que trabalham em salas de recursos multifuncionais da cidade de Colinas Tocantins. Para tanto, aplicou-se a sete docentes que trabalham nestas salas, uma entrevista semiestruturada que teve seus resultados analisados a partir de técnica de análise de conteúdo de Bardin (1977/2011) via análise de conteúdo por etapas descritas por Moraes (1999), com fundamentação teórica da psicodinâmica do trabalho. Concluiu-se que o professor da sala de recurso multifuncional, a depender da mobilização subjetiva impetrada contra o sofrimento que é inerente ao trabalho, poderá vivenciar prazer ou o chamado sofrimento patogênico. Dessa forma, o docente será submetido a vivências de sofrimento quando estiver inserido em espaços de trabalho negligentes para com suas questões subjetivas, inflexível em suas prescrições de trabalho e processo organizacional, evitando assim, a transformação do chamado trabalho prescrito em trabalho real. Por outro lado, o trabalhador docente vivenciará o prazer quando, em decorrência das suas estratégias de enfrentamento, conseguir transformar a realidade contextual da organização do trabalho, executando a partir de então, um labor com significados para si e para o meio social e que tenha certa aceitação, reconhecimento e valorização por meio da instituição e sociedade em geral. Sugere-se a construção de estratégias e politicas públicas com objetivo de promover estreitamento das relações entre o professor da sala de recurso multifuncional e a comunidade institucional, social e familiar com o objetivo de que todos tenham uma compreensão adequada das atividades educacionais executadas e da importância das mesmas para as pessoas marginalizadas socialmente e dentro da própria família, em suas necessidades e potencialidades. / In Brazil, the construction of public policies aimed at people with special educational needs began at the end of the nineteenth century, a period in which, based on European experiences, the first institutions were created with the purpose of attending to those who at the time had some deficiency auditory, visual and physical. It was only in the 50s and 60s that truly began the construction of more contemplative services and consistent with the needs of the Brazilian population. Thus, there is the so-called specialized educational service that among its several services exists the multifunctional resource room, a space located in the school where the specialized educational service is offered to students with special educational needs. In this context, the present research, of a qualitative, exploratory and descriptive nature, aimed to identify the main experiences of pleasure and suffering of teachers working in multipurpose resource rooms in the city of Colinas Tocantins. In order to do so, it was applied to seven teachers working in these rooms, a semi-structured interview that had its results analyzed using Bardin's content analysis technique (1977/2011) via content analysis in stages described by Moraes (1999), with theoretical foundation of work psychodynamics. It was concluded that the teacher of the multifunctional resource room, depending on the subjective mobilization against the suffering that is inherent in work, could experience pleasure or the so-called pathogenic suffering. In this way, the teacher will be subjected to experiences of suffering when he is inserted in negligent work spaces for his subjective questions, inflexible in his prescriptions of work and organizational process, thus avoiding the transformation of the so-called prescribed work into actual work. On the other hand, the teaching worker will experience pleasure when, as a result of his coping strategies, he is able to transform the contextual reality of the work organization, from then on, carrying out work with meanings for himself and for the social environment and having acceptance, recognition and appreciation through the institution and society in general. It is suggested the construction of strategies and public policies with the objective of promoting closer relations between the teacher of the multifunctional resource room and the institutional, social and family community so that all have an adequate understanding of the educational activities carried out and the importance socially marginalized people and within the family itself, in their needs and potentialities.

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