A Síndrome Dolorosa Femoropatelar (SDFP), possui etiologia multifatorial e acomete cerca de 7 a 15% da população, em sua maioria mulheres, jovens, adultas e ativas. Ela causa dor anterior ou retropatelar e é exacerbada durante gestos motores funcionais, tais como subir e descer escadas ou permanecer longos períodos de tempo sentado, agachado ou ajoelhado. Como a avaliação diagnóstica desta síndrome ainda é indireta, diversos mecanismos e metodologias buscam realizar uma classificação que diferencie os portadores de SDFP com relação aos assintomáticos. Deste modo, o objetivo desse trabalho é estudar as relações entre os sinais eletromiográficos (EMG) do músculo quadríceps em indivíduos com SDFP durante exercícios isométricos distintos (dissipativo e conservativo) em diferentes ângulos da articulação tíbiofemoral, e compará-los com os indivíduos sem SDFP. Foram analisadas a intensidade do sinal EMG (RMS), a frequência mediana (Fmed) e a frequência em 95% (F95) do espectro de potência dos músculos vasto medial oblíquo (VMO), vasto lateral (VL) e reto femoral (RF) para as contrações isométricas dissipativa e conservativa. Participaram deste estudo 24 voluntários do sexo feminino (17 assintomáticos e 7 com SDFP) que realizaram 18 contrações nos ângulos de 90º, 60º e 20º de extensão de joelho, utilizando 30% da carga voluntária máxima. Eletrodos EMG foram posicionados nos referidos músculos para a coleta dos dados, os quais foram posteriormente tratados e processados, possibilitando a análises do sinal EMG nos domínio do tempo e da frequência. Os resultados indicam que o RMS do sinal EMG apresenta-se distinto entre as contrações isométricas para o grupo sintomático e evidenciam que não existe uma relação de intensidade de contração EMG de um músculo comparativamente ao outro quando se altera o gesto motor. A Fmed de VMO e VL podem ser utilizadas como ferramenta na detecção de SDFP, visto que atuam de maneira distinta entre os grupos. A F95 do músculo VMO comporta-se de um modo diferente entre os grupos, sendo que durante a contração isométrica dissipativa em 20º e 60º, seus valores em SDFP foram maiores do que no grupo Controle. Desta maneira, foi possível relatar que é possível diferenciar a SDFP, ou até mesmo detectá-la, utilizando parâmetros EMG de padrões diferentes de contrações isométricas. / The Patellofemoral Pain Syndrome (PFPS) has a multifactorial etiology and affects approximately 7-15% of the population, mostly active young women. PFPS causes retropatellar pain, that is exacerbated during motor functional gestures, such as climbing stairs, sitting, squatting or kneeling for long periods of time. Since the diagnostic evaluation of this syndrome is still indirect, different mechanisms and methodologies seek to achieve a classification able to distinguish patients with PFPS from asymptomatic ones. Thus, the purpose of this study is to find the relationship between the electromyographic (EMG) signals of quadriceps in individuals with and without PFPS during isometric exercises (dissipative and conservative) at different angles of the tibiofemoral joint, to analyze the signal pattern of the control subjects and to compare with the SDFP group. We compared the root means square (RMS) of the EMG signal, median frequency (Fmed) and frequency in 95% of the power spectrum (F95) on the vastus medialis oblique (VMO), vastus lateralis (VL) and rectus femoris (RF) for dissipative and conservative contractions. 24 female volunteers participated in this study (17 asymptomatic patients and 7 with PFPS), who performed 18 contractions at angles of 90º, 60º and 20º of knee extension, using 30% of the maximal voluntary contraction. EMG electrodes were placed on those muscles for data collection, which were further processed using AqDAnalysis software for selection of traits, and MatLab® for processing and analysis of the signal in time and frequency domain. The results indicate that the RMS of EMG signal presents differences among the isometric contractions for the symptomatic group and show that there is a relationship of contraction of a muscle compared to the other when it changes the motor gesture. The Fmed of VMO and VL can be used as a tool in the detection of PFPS, because it acts differently in each group. The F95 of the VMO muscle behaves differently between groups, and during the dissipative isometric contraction at 20º and 60º, their values were higher in PFPS than in the control group. Thus, it was possible to report that it is possible to differentiate the PFPS, or even detect it using EMG parameters of different patterns of isometric contractions

Introdução- Pacientes portadores de Síndrome Dolorosa Complexa Regional- I (SDCRI) lombar apresentam componente autonômico simpático associado à dor lombar facetaria, são submetidos de forma rotineira à sequência de 4 bloqueios autonômicos associado ao bloqueio do ramo mediano facetário, implicando em 4 procedimentos ambulatoriais por paciente, por semestre. Este estudo visou avaliar a eficácia da realização de ablação por radiofrequência após a realização do bloqueio teste. Métodos- Após aprovação do Comitê de Ética em Pesquisa e consentimento, 25 pacientes portadores de SDCR-I em membros inferiores e dor articular facetária lombar associada foram de forma prospectiva, submetidos a: 1) 4 sessões com intervalos semanais de bloqueio do ramo mediano facetário lombar de L2 a L5 bilateral, associado ao bloqueio do gânglio simpático autonômico L3. Quando a dor atingisse graduação VAS= 4 cm, foi considerado necessário repetição dos procedimentos realizados, e este tempo correspondeu ao tempo de analgesia, sendo calculado o custo anual e efeitos adversos por paciente. Os mesmos pacientes foram submetidos posteriormente a: 1) Bloqueios testes simpático e facetário, seguido de: 2) ablação por radiofrequência (RF) do ramo mediano facetário lombar de L2 a L5 bilateral, com 45 V, 80 segundos, 80 oC, + ablação por RF do gânglio simpático lombar de L3-L4 do lado acometido, 45V, 80 oC, 80 segundos em cada nível acometido, sob sedação consciente, com midazolam e alfentanil por via venosa. Cada paciente atuou como seu próprio controle. Resultados- 21 pacientes participaram da avaliação final. Cada paciente foi submetido a uma sequência semestral de bloqueios, sendo o tempo de analgesia após término do quarto procedimento 5±1 meses, e o custo anual de R$ 15.000,00. Quando os mesmos pacientes foram submetidos à RF, o tempo de analgesia foi em média 15±2 meses (p<0,001), havendo economia no primeiro ano de realização de RF de 23% no custo final e de 32% a 36% nos anos subsequentes, calculado por extrapolação. Durante o período de analgesia, a capacidade para realização de atividades rotineiras e a qualidade de sono melhoraram. Não foram observados efeitos adversos. Discussão- A realização de RF resultou menor número de internações anuais, menor custo anual e maior comodidade para o paciente, com mesma eficácia durante período de analgesia. / Introduction- Patients with Complex Regional Pain Syndrome type-I (CRPS-I) in lower members, often also present lumbar articular facetary pain, and are submitted as part of routine to a sequence of 4 weekly sympathetic blocks combined to facetary block, which sequence is usually repeated after six months for pain control. The study was designed to evaluate the efficacy of a test block followed by radiofrequency efficacy. Methods- After ethical approval and consent, 25 patients with CRPS-I in lower members were submitted to a 4-weekly sympathetic block at L3, combined to bilateral lumbar facetary block fromL2-L5. The sequence was repeated when pain VAS reached 4 cm, and this period was defined as time of analgesia. Thereafter, the same patients were submitted to a test block followed by radiofrequency (RF ablation of sympathetic ganglion L3 and L4 and bilateral ablation of facetary lumbar median branch from L2-L5), 45 V, 80 sec, 80 oC, under conscious sedation. Patients acted as their own control related to analgesia, routine activities, sleep and costs. Results: 21 patients completed the study. The analgesia time after the 4-block sequence was 5±1 months and the annual cost R$ 15.000,00 (USA$5000). The analgesia time after RF was 15±2 months (p<0.001) and the costs were reduced by 23% in the first year and 32%-36% in the following years extrapolation. Routine capacity and sleep at night were equally improved during analgesia for both treatments. There were no adverse effects. Discussion- Test block followed by RF resulted in 15 months of analgesia compared to 5 months for the routine technique of 4-blocks, in improved capacity and sleep comfort at night. Besides that, RF was costly effective, and reduced costs by 23% during the first year evaluation, followed by 32% to 36% cost reduction in following years, by extrapolation.

Subir e descer escadas são atividades funcionais habituais e muito relatadas como queixa principal por pacientes com alterações ortopédicas como a síndrome dolorosa femoropatelar - por ser um movimento que acarreta descarga de peso unilateral e assim causa um aumento da dor - e por pacientes com afecções neurológicas - devido à dificuldade na execução deste gesto. Além disso, a subida e descida de escadas é habitualmente utilizada como técnica terapêutica na reabilitação destes pacientes; porém poucos estudos foram realizados com o intuito de caracterizar este gesto e, estes estudos, concluem que a alta variabilidade dos dados não permite confirmar os resultados. Estudos com pacientes com dor femoropatelar usualmente avaliam estes sujeitos com eletromiografia de superfície e sugerem que exista um déficit de equilíbrio na musculatura estabilizadora da patela e que esta é a causa da dor nestes pacientes; porém, também há uma grande variabilidade nos resultados encontrados, não sendo possível confirmar esta hipótese. Neste contexto, este estudo teve o objetivo de verificar quais parâmetros do sinal eletromiográfico apresentaram boa reprodutibilidade e menor variabilidade e são, portanto, mais adequados para caracterizar o gesto proposto, podendo ser utilizado para comparar grupos de indivíduos com e sem dor femoropatelar. Para isto, foi utilizada a eletromiografia para avaliar a atividade dos músculos vasto lateral e vasto medial do quadríceps durante a subida de escada em 39 indivíduos clinicamente saudáveis e 23 indivíduos com dor femoropatelar. Os resultados mostraram que os parâmetros que apresentaram boa reprodutibilidade entre os dois dias de avaliação foram: início de ativação, duração da contração muscular, tempo mediano da contração, intensidade do sinal, co-ativação muscular e frequência mediana. Dentre estes parâmetros, aqueles que permitiram diferenciar os grupos de estudo foram o tempo mediano da ativação, que ocorreu mais tardiamente nos indivíduos com dor e a co-ativação muscular, que demonstrou menor porcentagem de ativação conjunta nos indivíduos com dor. Estes dados indicam uma alteração no controle neuromotor durante a subida de escada, sugerindo que a abordagem clínica deva passar por treinos de equilíbrio, coordenação e propriocepção, para melhorar a estabilidade articular durante a realização de atividades dinâmicas. / Go up and down stairs are functional activities very habitual and reported as complaint for patients with orthopedic alterations as patellofemoral pain syndrome because it is a movement that carries unilateral weight bearing and thus cause an increase in pain and for patients with neurological disorders due to the difficulty in carrying out this gesture. Moreover, the ascent and descent of stairs is usually used as a therapeutic technique in the rehabilitation of these patients, but few studies have been conducted in order to characterize this gesture and, these studies conclude that the high variability of the data does not confirm the results. Studies on patients with patellofemoral pain usually assess these subjects with surface electromyography and suggest that there is a balance deficit in the patella stabilizer muscles and that this is the cause of pain in these patients, but there is also a great variability in the results, that does not allow to confirm this hypothesis. In this context, this study aimed to determine which parameters of electromyographic signals showed good reproducibility and low variability and are, therefore, more appropriate to characterize the proposed gesture and can be used to compare groups of individuals with and without patellofemoral pain. For this, we used electromyography to evaluate the activity of the vastus lateralis and vastus medialis of the quadriceps during stair climbing in 39 clinically healthy individuals and 23 individuals with patellofemoral pain. The results showed that the parameters with good reproducibility between the two days of evaluation were: onset, duration of muscle contraction, median time of contraction, intensity of activation, muscular co-activation and median frequency. Among these parameters, those that could differentiate the groups were the median time of activation, which occurred later in subjects with pain and muscle co-activation, which showed a lower percentage of combined activation in individuals with joint pain. These data indicate a change in neuromotor control during stair climbing, suggesting that the clinical approach should undergo training of balance, coordination and proprioception, in order to improve joint stability while performing dynamic activities.

The current research examined the proposition that individuals who were securely attached had a fundamentally different reaction and experience of chronic pain to the experience of individuals with an insecure attachment style. A biopsychosocial model of chronic pain was created that included the variables of attachment style, pain, depression, anxiety, somatisation, quality of life, function, disability, neuroticism, age and gender. Three cross-sectional quantitative studies and one qualitative study were conducted. Participants were (a) patients from a multidisciplinary pain centre in a major public hospital, and (b) members of the general population with chronic pain who were recruited from both urban and rural settings, across various community support groups. The total sample was 470. Instruments for the quantitative studies included the Revised Adult Attachment Scale (Collins & Read, 1990), the McGill Pain Questionnaire (Melzack, 1975), the Pain Patient Profile (Tollinson & Langley, 1992), the Quality of Life Inventory (Frisch, 1994), the International Association for the Study of Pain Assessment Protocol (International Association for the Study of Pain, 1986), the Migraine Disability Scale (Stewart, Lipton, Kolodner, Liebermann, & Sawyer, 1999), and the short form of the Eysenck Neuroticism Scale (Eysenck, Eysenck, & Barret, 1985). The clinical and non-clinical participants with a diagnosis of chronic pain syndrome were partitioned as securely or insecurely attached. In the clinical sample, the proportion of securely attached individuals was less than one quarter of the group, while in the non-clinical sample the proportion of individuals in the securely attached group was 50%. For Study 1, (200 individuals from the clinical sample), the groups were partitioned using the classification criteria of Collins and Read (1990). Securely attached participants = 27%, insecurely attached 73%. An analysis of effect of attachment style on overall pain showed that the Securely Attached group reported less overall pain than the Insecurely Attached group. For Study 2, (using the total clinical sample), the sample comprised 27.3% securely attached and 72.7% insecurely attached participants. The Securely Attached group reported less overall Pain, less Negative Affect and Somatisation than the Insecurely Attached group, and higher levels of Quality of Life. Somatisation provided a significant unique contribution of variance to predicting overall Pain, providing some support for the biopsychosocial model, and Negative Affect (Depression and Anxiety combined) made a significant unique contribution to Quality of Life, explaining 26% of the variance. Gender was unrelated to any variable. For Study 3, the sample consisted of rural and urban participants, and the rural group was significantly older than the urban group. No other differences were found. The groups were combined to form the non-clinical group. The group was evenly divided (50%) between securely and insecurely attached groups. Gender was unrelated to any variable. For the non-clinical group, using the variables investigated in Study 2, there was no difference on overall pain scores, but negative affect and somatisation were higher and quality of life lower in the insecure group than in the secure group. No differences were found on Pain Intensity but Pain Pattern differed between the groups. Three new variables were added to the model - Neuroticism, Function and Disability. Disability and Function were significantly different between the attachment style groups. Age was significantly related to lower pain scores, less loss of function, less disability and higher quality of life. Pain scores were most related to somatisation, with age and quality of life contributing significant variance. Neuroticism added further to this explanation. Negative Affect made the most contribution to the variance explained in quality of life, and neuroticism and function made no significant contribution. Neuroticism and Attachment Style contributed significant amounts of variance to Function. To compare the Secure and Insecure Attachment groups in the Clinical and Non-clinical samples, a matched groups study, N = 190, was conducted. Clinical and non-clinical participants were matched for Age, Gender and Attachment Style. No differences were reported on overall pain between the attachment groups, but differences existed on negative affect, somatisation and quality of life. For sample type, the clinical group reported higher overall pain scores, less negative affect and less somatisation, but no differences were found on quality of life, compared to the non-clinical group. Study 4 was a qualitative study that used structured interviews of 24 clinical and non-clinical participants matched for age, gender, attachment style and etiology. The securely attached group reported having extensive, positive social support, high community involvement and appropriate reliance on medical and allied health care and medications. The insecurely attached group reported more problems with physical pain and psychological distress, less social support, less function and more perceived disability. The insecurely attached group reported more use of medical, allied and alternative health resources. Older securely attached individuals reported the lowest overall pain scores and the highest quality of life. These results support the hypotheses that a secure attachment style contributes to more positive outcomes for individuals with chronic pain syndrome and were consistent with a model of chronic pain that includes biological, psychological and social variables.

Diss. (sammanfattning) Umeå : Univ., 2006. / Härtill 6 uppsatser.

Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder characterized by both central and peripheral symptoms that can be debilitating in children. CRPS treatment typically consists of intensive physical, occupational, and psychological therapy with evidence supporting the efficacy of this approach. Among these outcomes, some patients report significant improvements in pain while others report no change. Identifying baseline predictors of treatment resistance would refine our treatment approach and provide additional targets for intervention. The current study examined baseline brain structure via cortical thickness and gray matter volume (GMV) in 29 pediatric CRPS patients enrolled in an intensive pain rehabilitation program. All participants underwent MRI using a high-resolution T1-weighted sequence. Patients were categorized as pain treatment “responders” (n=19) or “non-responders” (n=10) based on change in reported pain levels from admission to follow up. Compared to treatment responders, non-responders demonstrated significantly less GMV in the bilateral nucleus accumbens p<0.05 and right: putamen p<0.01, pallidum p<0.05, and amygdala p<0.05. Furthermore, treatment non-responders exhibited significant cortical thickening in the left anterior insular cortex and medial frontal gyrus, and cortical thinning in the bilateral precentral gyrus and superior frontal gyrus; right: middle frontal gyrus, fusiform gyrus, inferior temporal gyrus, middle temporal gyrus, and anterior prefrontal cortex; and left: parahippocampal gyrus. Though we did see significant thinning of the primary motor cortex in treatment non-responders compared to responders, the majority of our findings were localized to regions associated with reward, motivation, learning, and emotion. We, therefore, postulate that treatment non-responders, when compared to responders, likely have an intrinsically reduced reward responsiveness, diminished motivation, and impaired learning, overall contributing to their negative treatment outcomes and chronification of pain. In conclusion, these baseline differences overall suggest these regional morphometric alterations may potentially serve as predictors of treatment response in pediatric CRPS. Furthermore, these areas may also indicate possible targets for future treatment.

The Gluteus Medius and the Tensor Fascia Lata are two of the main muscles involved in the action of hip abduction. This action is important for both dynamic movements in athletic pursuits and in every day ambulation. Weakness in these muscles has been connected to multiple injuries in the lower limb, but the question of the casual relationship between gait change, hip abductor weakness, and lower limb injury is still up for debate. As presented by the current research, younger populations tend to have overuse injuries with females having a greater susceptibility for injuries connected to hip abductor weakness, and older populations tend to have injures related to atrophy and degeneration of either the hip abductor muscles or the joint surrounding the hip. Research in this field has increasingly focused on sub-sets of the populations, such as just females or just males, trying to pinpoint the role that hip abductor weakness plays in these injuries. By trying to minimize or even eliminate the confounding variables that have previously made it difficult to determine the role hip abductor weakness plays in these gait changes and injuries, these studies have been able to make more clear conclusions at the expense of making a broader generalization. Similarities and differences between how the sub-groups present with hip abductor weakness are discussed, as well as discrepancies observed within the research done on similar cohorts. Future directions for research in this field are discussed, as well as implications for clinical implementation of targeted rehabilitation programs to ensure the best possible outcomes.

Cenário clínico: A síndrome dolorosa miofascial (SDM), causa comum de dor musculoesquelética, pode ser incapacitante e desafiadora terapeuticamente, devido à ineficácia dos tratamentos convencionais para dor. Intervenções terapêuticas alternativas precisam ser pesquisadas para alcançar vias do processo de doença não contempladas com a terapêutica clássica. Dentre estas, o uso da melatonina, com efeitos cronobiótico, ansiolítico e analgésico, tem se apresentado como uma opção terapêutica atrativa no tratamento da SDM, que cursa com alterações de sono, dor, sintomas depressivos e de ansiedade. Objetivos: Avaliar a eficácia da melatonina exógena na redução da dor, no limiar de dor à pressão (LDP) e na qualidade de sono de pacientes com SDM facial. Métodos e Resultados: Um estudo randomizado, controlado foi realizado em 45 mulheres com dor miofascial, com idades entre 18 e 40 anos, segundo critérios Research Diagnostic Criteria for Temporomandibular Disorder (RDC/TMD). A eficácia da melatonina oral foi avaliada na redução da dor e melhora tanto do limiar de dor a pressão (LDP) como da qualidade do sono. Os participantes foram randomizados para receber 5 mg / dia de melatonina, 5 mg / dia ciclobenzaprina, ou placebo durante um período de quatro semanas. O efeito absoluto das intervenções, apresentado como ES (tamanho do efeito) sobre a dor: placebo versus melatonina foi de 2,08 (1,17-2,97) e de ciclobenzaprina vs placebo foi de -1,25 (0,45-2,06)]. O número de pacientes necessários para tratar (NNT) para evitar a dor moderada a intensa foi 3 (95% CI, 2-4) e 18 (95% IC, 9 a a) nos grupos de melatonina e de ciclobenzaprina, respectivamente, em relação ao placebo. O ES no LDP melatonina vs placebo e ciclobenzaprina vs placebo foi de 2,72 (1,69-3,75) e 1,01 (0,23-1,79), respectivamente. O ES na escala visual analógica de Qualidade de Sono (VASQS) utilizada para avaliar a forma como as pacientes se sentiram ao acordar, durante o período de tratamento, foi nos grupos melatonina versus placebo de 2,47 (1,49-3,45) e 1,01 (0,23-1,79), respectivamente. Conclusão: Melatonina foi mais eficaz do que placebo para melhorar a dor miofascial crônica facial e ambos os tratamentos foram mais eficazes do que placebo para melhorar o LDP e a qualidade de sono. / Background: The Myofascial Pain Syndrome (SDM), a common cause of musculoskeletal pain, can course with disability and can be a therapeutical challenge, due to the ineffectiveness of conventional treatments for pain. Alternative therapeutic interventions must be researched to achieve the process of the disease process that in not dealt with the classical therapy. Among these, the use of melatonin, which takes effect chronobiotic, anxiolytic and analgesic, has been presented as an attractive therapeutic option in the treatment of SDM, which leads to sleep disturbances, pain, anxiety and depressive symptoms. Objectives: Evaluate the efficacy of exogenous melatonin in reducing pain, pain pressure threshold (PPT) and the sleep quality of patients with chronic myofascial face pain. Methods and Results: A randomized, controlled trial was conducted with 45 females, aged 18 to 40 years who presented myofascial pain according to the Research Diagnostic Criteria for Temporomandibular Disorder (RDC/TMD) guidelines. The efficacy of oral melatonin was evaluated in reducing pain and improving both the pain pressure threshold (PPT) and sleep quality. Participants were randomized to receive 5 mg/day melatonin, 5 mg/day cyclobenzaprine, or a placebo during a four-week period. The absolute effect of interventions, presented as ES (effect size) on pain for melatonin vs. placebo was 2.08 (1.17 to 2.97) and for cyclobenzaprine vs. placebo -1.25 (0.45 to 2.06)], respectively. The Number of Patients Needed to be Treated (NNT) to prevent moderate to intense pain was 3 (95% CI, 2 to 4) and 18 (95% CI, 9 to ) in the melatonin and cyclobenzaprine groups, respectively compared to the placebo. The ES on the PPT for melatonin vs. placebo and cyclobenzaprine vs. placebo was 2.72 (1.69 to 3.75) and 1.01 (0.23 to 1.79), respectively. The ES on the Visual Analog Sleep Quality Scale (VASQS) scores used to assess how they felt when they woke up during the treatment period for the melatonin vs. placebo were 2.47 (1.49 to 3.45) and 1.01 (0.23 to 1.79), respectively. Conclusion: Melatonin was more effective than placebo for improving chronic myofascial face pain and both treatments were more effective than placebo for improving sleep quality and the PPT.

Cenário clínico: A síndrome dolorosa miofascial (SDM) pode ser incapacitante e desafiadora terapeuticamente, devido à ineficácia dos tratamentos convencionais para a dor. Objetivos: O objetivo deste estudo foi avaliar a eficácia da estimulação intramuscular (EIM) na redução da dor e melhora da saúde física e mental de pacientes com SDM. Conduzimos um ensaio clínico randomizado controlado em 60 mulheres, com idades entre 20 e 40 anos, que foram randomizadas para receber EIM, infiltração com lidocaína e falsa eletroneuroestimulação transcutânea (TENS-placebo), duas vezes por semana, durante 4 semanas. Resultados: A redução do percentual de alívio de dor observada na escala análogo-visual de dor (EAVD) durante a primeira semana após o final do tratamento no grupo TENS-placebo foi de 14,01 [intervalo de confiança (IC) 95%; 2,89 a 25,12], o que foi significativamente menor em comparação com o observado nos grupos de infiltração com lidocaína e de EIM, de 43,86% [IC 95%; 26,64 a 61,08] e de 49,74% (IC 95%, 28,95 a 70,54), respectivamente. O tamanho do efeito (TE) sobre a dor, na comparação de TENS-placebo com a EIM e infiltração com lidocaína foi de 1,48 [IC 95%; 0,76 a 2,19] e de 1,20 [0,43 a 1,40], respectivamente. O tamanho do efeito (TE) sobre a dor, na comparação de TENS-placebo com a EIM e infiltração com lidocaína foi de 1,48 [IC 95%; 0,76 a 2,19] e de 1,20 [0,43 a 1,40], respectivamente. A EIM melhorou significativamente os escores da saúde física e mental e o limiar de dor à pressão (LDP). Valores baixos do LDP, antes do tratamento, preveem uma redução do risco de 43% para apresentar um TE pequeno/moderado na dor no grupo da EIM e atitudes positivas, em todas intervenções, aumentaram a probabilidade para uma redução significante na intensidade da dor relatada.. Conclusões: A EIM foi mais efetiva do que o TENS-placebo e pelo menos equivalente à infiltração com lidocaína no tratamento da SDM e na melhora dos sintomas depressivos e da saúde física e mental. / Background: Myofascial pain syndrome (MPS) can be disabling and therapeutically challenging, because of the inefficacy of traditional pain treatment. Objectives: The objective of this study was to evaluate the efficacy of intramuscular stimulation (IMS) in reducing pain and improving physical and mental health in patientes with MPS. Methods: We conducted a controlled trial in 60 females, aged 20 to 40 years, where the participants were randomized to receive IMS, lidocaine infiltration or TENS-placebo twice a week for 4 weeks. Results: The reduction in the percent pain on a VAS (Visual Analogue-Scale) after the end of the first week of treatment in the TENSplacebo group was 14.01 [95% confidence interval (CI); 2.89 to 25.12], which was significantly lower than for the lidocaine infiltration and IMS groups, which reported 43.86% [95% CI; 26.64 to 61.08] and 49.74 % (95% CI, 28.95 to 70.54), respectively. The ES (effect size) on pain comparing TENS-placebo vs. IMS and TENS-placebo vs. lidocaine-infiltration were 1.48 [95% CI; 0.76 to 2.19] and 1.20 [0.43 to 1.40], respectively. IMS significantly improved the mental and physical health scores and the PPT. Lower PPT values pretreatment predicted a reduction of the risk by 43% of the small/moderate ES in terms of pain in the IMS group and positive attitudes, in all interventions, improved the probability a significant reduction in current pain intensity. Conclusions: IMS was more effective than TENS-placebo and at least equivalent to lidocaine infiltration in treating MPS and improving physical and mental health.

Made available in DSpace on 2014-06-11T19:25:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-05-09Bitstream added on 2014-06-13T18:53:13Z : No. of bitstreams: 1 chambo_rc_me_botfm.pdf: 605131 bytes, checksum: 81f0a6d5dda1782f51f5b580a20f8761 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / A Síndrome da Dor Pélvica Crônica (SDPC) é uma nova categoria na classificação atual das prostatites. A causa da SDPC é desconhecida, a teoria mais aceita é o refluxo intraprostático. Não há estudo que comprove qual o melhor tratamento. A finasterida, uma das drogas utilizadas para o tratamento, é um antiandrogênio que bloqueia a enzima 5-alfa redutase, diminuindo o tamanho da próstata. A finasterida agiria na SDPC reduzindo o tecido glandular prostático, diminuindo a tensão intraprostática e conseqüentemente o refluxo intraprostático. Avaliar a efetividade e a segurança da finasterida no tratamento da SDPC. Uma revisão sistemática de ensaios clínicos aleatorizados foi realizada, sem restrições de língua, datas ou outras considerações. As fontes de informação utilizadas foram Medline, Registro de Ensaios Controlados da Cochrane, Embase, Lilacs e SciELO. Contato com autores de artigos, laboratórios que comercializam finasterida e revistas médicas em geral e específicas. Foram incluídos pacientes com diagnóstico da SDPC tipo IIIA e/ou IIIB, participantes de estudos em que foi comparado o uso da finasterida com placebo ou outro tipo de tratamento. Os desfechos clínicos avaliados foram os questionários dos sintomas prostáticos, exames para avaliar a melhora bioquímica ou variável fisiológica e eventos adversos. A coleta de dados e análise foram realizadas por dois revisores que inspecionaram as referências encontradas independentemente pela estratégia de busca e aplicaram os critérios de inclusão nos estudos selecionados usando os critérios de qualidade metodológica descritos no Cochrane handbook. A escala de Jadad e Schutz também foram usadas. Os dados dos estudos elegíveis foram sumarizados em metanálise. A análise estatística foi realizada utilizando o... / Chronic Pelvic Pain Syndrome (CPPS) is a new category in the current classification of prostatitis. The cause of CPPS is unknown; the most accepted theory is intraprostatic ductal reflux. The best treatment is not known. Finasteride, a specific type II 5a-reductase inhibitor, decreases the size of the prostate. A potential mechanism of action for finasteride is the reduction of the intraprostatic tension due to the glandular shrinkage, decreasing the intraprostatic ductal reflux. To assess the effectiveness and harms of finasteride in the treatment of CPPS. A systematic review of randomized controlled trials was performed, with no restrictions on language, dates or other considerations. The information sources used were Medline, the Cochrane Central Register of Controlled Trials, Embase, Lilacs and SciELO; contact authors of articles, laboratories that work with finasteride and general and specific medical magazines. It included participants with a diagnosis of CPPS type IIIA and/or IIIB taking part of studies comparing the use of finasteride to placebo or another type of treatment. The clinical outcomes evaluated were the questionnaires of prostatic symptoms, improvement in biochemical or physiologic variables and adverse events. The collecting data and analysis were performed by two reviewers that checked the found references independently by the search strategy, and applied the inclusion criteria in the selected studies using the criteria of methodological quality described on Cochrane Handbook. The Jadad and the Schutz scales were also used. After finding all eligible studies, the data were summarized in meta-analysis. The statistical analysis was undertaken using the MetaView statistical program within Review Manager software of the Cochrane Collaboration. Three studies with 181 patients were included. The length ...(Complete abstract click electronic access below)