Hypertrophic scarring is a common occurrence for severe burn victims leading to major functional, physiological, and aesthetic effects to the patients. Limiting the hypertrophic scarring of the patients alleviates the functional, physiological, and aesthetic effects. Silicone gels, over the past decade, have been widely used to remediate and limit hypertrophic scarring but the mechanism of action is yet to be determined. One explanation has been that hydration of the outermost area of the burn is induced by the silicone gel . However, non-silicone polymers which increase hydration could not mimic the effect. An alternative interpretation is that there may be silicone species that migrate from the silicone gel into the viable tissue to mediate reactions in the extra-cellular matrix that result in a decreased deposition of excessive amounts of collagen - a central feature of the hypertrophic scar. A novel and informative technique to study these species is MALDI-TOF/MS (Matrix Assisted Laser Desorption Ionisation-Time of Flight Mass Spectrometry) in conjunction with gel permeation chromatography. MALDI-TOF/MS, which has allowed the detection of intact molecular species that were not possible with more established mass spectrometric techniques. The mobile species that may migrate from polydimethylsiloxane medical gel sheeting into skin have been identified by MALDI-MS. The bulk gel contains predominantly cyclic oligomers with a mass distribution peaking at n = 19 (number of repeating siloxane units), but in an aqueous environment the species at the surface of the silicone medical gel are predominantly methyl/methylol-terminated linear siloxanes. By using a gelatine matrix as a model substrate, the distribution of silicon after application of the silicone gel for 16 weeks was determined by Energy-dispersive X-Ray mapping of the sectioned gelatine. The association of the linear and cyclic oligomers with proteins relevant in hypertrophic scarring are considered. The mobility of silicone species across stratum corneum was confirmed by Attenuated Total Reflectance Fourier Transform Infrared spectroscopy (ATR-FT/IR). This method confirms our hypothesis that not only are the low molecular weight silicone species mobile, but also that they do traverse the natural barrier, the stratum corneum, to levels that are detectable by ATR after a continuous application over approximately 11 days. Invitro studies of the effects of LMWS on primary line fibroblast cells indicate a response that down regulates the proliferation of fibroblast cells and protein production. Preliminary results indicate that a family of pendant functional LMWS are effective in down regulating hypertrophic-derived fibroblast primary cells. Studies on hypertrophic scar tissue treated with silicone medical gel indicate that LMWS permeate across the stratum corneum into viable scar tissue. In some areas, the LMWS tend to pool as detected by SEM/EDX elemental silicon analysis. These areas of LMWS pooling tend to be composed of highly disorganised collagen nodules.

Qu'est-ce qui refait surface dans l'image ? Comment est-ce que cela refait surface ? Ces interrogations prennent leur origine dans des réalisations plastiques principalement centrées autour de problématiques graphiques, organisées en deux ensembles : l'image-trace correspondant à des dessins résultant d'empreintes et de dépôts, et l'image-palimpseste s'ordonnant par strates au sein de surfaces bidimensionnelles ou d'installations. L'objectif des recherches menées dans cette thèse est de saisir comment l'image peut constituer une métaphore du processus mnésique, et s'inscrire entre mémoire et oubli. L'image-trace semble pouvoir évoquer le fonctionnement de la mémoire par sa qualité d'empreinte qui se pose comme une trace mnésique précaire, et qui peut être le réceptacle de particules de matière-mémoire déposée. L'image-palimpseste donne à voir par transparence un feuilletage faisant écho aux différentes étapes de la poïétique d'une œuvre hétérochronique. Tantôt le passé est renvoyé à la profondeur opaque et aux plis de l'image, tantôt il est en surface dans une mosaïque temporelle éclatée, formant une mémoire composite à partir de fragments qui refont surface. Le retour à la surface se manifeste également dans des œuvres actualisant la résurgence répétée d'une figure survivante. Elle est une forme errante dans une achronie, tel un écho de mémoire teinté d'oubli. Finalement, dans des dispositifs entropiques, l'oubli lui-même devient, à un second niveau, espace de projection pour une nouvelle mémoire, provisoire, construite à partir de la perte : la mémoire de l'oubli. / What resurfaces in the image? How does if resurface? These questions originate in artworks mainly centered on graphic characteristics and organized into two groups: the trace-image, which corresponds to drawings resulting from prints and sediments, and the palimpsest-image, which is stratified on two-dimensional surfaces or in installations. The objective of this thesis is to understand how the image can be a metaphor for the mnestic process, and how it is set between memory and oblivion. The trace-image seems to evoke the functioning of memory by its print status, presenting itself as a precarious memory trace, which may be the receptacle of sedimented memory-material particles. The palimpsest-image exposes a foliation that echoes the different stages of the creation process of a heterochronic work. The past is sometimes buried in the impenetrable depths and in the folds of the image, sometimes displayed on the surface in an exploded temporal mosaic, forming a composite memory from fragments, which resurface. The return to the surface is also apparent in works actualizing the repeated resurgence of a surviving figure. It is a wandering, achronic form, like an echo of memory tinged with oblivion. Finally, in entropie works, oblivion itself, on a secondary level, becomes a projection space for a new temporary memory, constructed from Joss: the memory of oblivion.

Abstract Protecting human skin against harmful UV radiation from the sun is an acute problem nowadays. Due to decreased thickness of the ozone layer, more UV light reaches the ground surface. This is one of the reasons of increased frequency of skin diseases. Titanium dioxide (TiO2) nanoparticles are embedded with sunscreens into the skin to attenuate UV radiation through absorption and scattering. The effectiveness of the interaction between particles and UV light depends on nanoparticle sizes. The aim of the study is to predict how the optical properties of the superficial layer of the human skin (stratum corneum) can be modified by means of nanoparticles, assuming that these particles are spheres and do not aggregate (this is achieved by application of some modern treatment techniques). In-depth distribution of TiO2 particles embedded into the skin after multiple applications of sunscreens was determined experimentally using the tape-stripping technique. A computer code implementing the Monte Carlo method was developed to simulate photon migration within the 20-μm thick horny layer partially filled with nano-sized TiO2 spheres, 35–200 nm in diameter. Dependencies of UV radiation of two wavelengths (310 and 400 nm) absorbed by and totally reflected from, as well as transmitted through the horny layer on the size of TiO2 particles were obtained and analyzed. Silicon nanoparticles of the same diameters were considered for comparison. The most attenuating particles were found for both cases. The harmful side-effect of UV light absorption by TiO2 particles is the generation of free radicals. Study of this phenomenon, using an electron paramagnetic resonance technique, was also carried out in this thesis. Comparison of the strength of the effect was done for two particle sizes administered onto either glass slides or porcine ear skin.

A pesquisa tem por objetivo, analisar as influências da urbanização concentrada (compacta), e de como essa característica altera as condições ambientais e o equilíbrio das formas de relevo local , modificando o estrato geográfico da paisagem. Para essa análise, t i vemos como supor te o mapeamento da evolução do uso da terra urbana em Taboão da Serra em dois momentos distintos, no período compreendido entre 1962 e 2007. O uso da terra tem contornos distintos no contexto intra-urbano, fato este que é traduzido pela evolução e pelo tipo de uso e ocupação dado à paisagem urbana em Taboão da Serra. Os processos geoecológicos encontram- se modificados na sua gênese e na sua estrutura, o que resulta em formas mais antropizadas do que em décadas passadas. A cidade de Taboão da Serra, é a sexta cidade mais compacta do Brasil , fato este que tem reflexos negativos sobre os processos naturais onde, a morfogênese é dominante por conta do intenso uso da terra seja ele para fins imobiliários como também pelo processo de intensificação da cobertura da superfície por materiais que interrompem a percolação das águas pluviais associado à retirada da cobertura vegetal . A escolha da cidade como área de estudo deu-se pelos motivos explicitados acima mas também, pelo fato de que através da comparação de dois momentos da ocupação urbana (1962 e 2007) que são caracterizadas pela intensificação do uso da terra (utilizando fotografias aéreas ) , é possível mapear e representar como o tipo de uso e ocupação pode comprometer em maior ou menor grau as condições geoecológicas de um geossistema. As unidades de paisagem urbana serão compartimentadas tendo como final idade a comparação para diagnosticar a relação atual entre relevo/ solo e uso da terra nesta c idade, que serão representadas na carta de Uso da Terra. / The research aims to examine the influences of urbanization concentrated (compact) , and how this feature changes the environmental conditions and the balance of local landforms by modi fying the geographic stratum of the landscape. For this analysis, we had to support the mapping of the evolution of urban land use in Taboão da Serra at two different times in the period between 1962 and 2007 . The use of land has different contours in the intra-urban context , a fact that is translated by the change in type of use and occupation since the urban landscape in Taboão da Serra. Geoecological processes are modified in their genesis and struc ture, resulting in forms more disturbed than in decades past . The city of Taboao da Serra, is the sixth most compact city of Brazil , a fact that has negative effects on natural processes where the dominant morphogenesis is due to the intense use of land be it for housing but also by the process of intensification of surface coverage by materials that disrupt the percolation of rainwater associated with the removal of the canopy. The choice of the city as the study area took place for the reasons explained above but also by the fact that by comparing two moments of urban occupation (1962 and 2007) which are characterized by the intensification of land use (using aerial photographs) it is possible to map and represent the type of use and occupation can affect a greater or lesser degree the conditions of a geoecological geosystem. The units of the urban lands cape will be compartmentalized view to the comparison to diagnose the current relationship between topography/soil and land use in this city, which will be represented in the land use map.

La peau est une interface essentielle entre le corps humain et son environnement externe. Au-delà du rôle de couche protectrice contre les agressions externes (mécaniques, thermiques, chimiques…), elle dispose de multiples fonctions de régulation comme l’absorption, la thermorégulation ou la synthèse d’hormones. L’étude de cette interface cutanée est importante, non seulement pour les spécialistes cliniques, mais également pour les chercheurs travaillant dans la compréhension des mécanismes des processus de transfert transcutanés. Longtemps considéré comme une simple couche de cellules mortes, le stratum corneum (SC, couche de la peau la plus externe) était considéré alors comme un acteur secondaire dans ces processus. Des études récentes montrent au contraire que cette couche cutanée, d’une épaisseur pouvant aller de 10 à 40 µm, joue un rôle primordial et déterminant. Ces études révèlent une architecture complexe, qui peut être représentée schématiquement par un empilement de cellules protéiniques (les cornéocytes) situées dans une matrice extracellulaire riche en lipides. Cette couche compacte est loin d’être complètement imperméable aux substances chimiques directement appliquées sur la peau. Nous proposons ici une approche physico-chimique visant à mettre en évidence les mécanismes d’interactions acide-base agissant à l’extrême surface du SC (i.e. une dizaine d’Angströms). En utilisant : i) les réactions de transfert de protons comme “sonde” et ii) une démarche multi-échelles basée sur des titrations de surface par angles de contact et par forces chimiques, nous déterminons quantitativement le rôle de chacune des composantes du SC (i.e. cornéocytes et lipides) dans ce type d’interactions. / Stratum corneum (SC) is a heterogeneous tissue composed of lipid-depleted corneocytes embedded in a lipid-enriched extracellular matrix. It comes from the epidermal differentiation of the skin. The wetting properties of this upper layer are of major interest in the understanding of interfacial phenomena, such as adhesion of microorganisms or proliferation of resident flora. Until now, the wettability behaviour has been characterized through different parameters such as surface energy, critical surface tension, or hydrophilia, via macroscopic contact angle measurements. But this method does not allow to discriminate the effect of the corneocytes with the one of the extracellular matrix on the final surface properties, because of the size of the liquid drop. This work, performed in vitro on human skin explants provided by Pierre Fabre Dermo-Cosmetics, consists in understanding the wetting properties of the SC from macroscopic and nanoscopic points of view. Initially, it is compulsory to thoroughly describe at different scales the physical chemistry of our material, i.e. in vitro SC. Then, knowing that macroscopic contact angles are sensitive to the pH of the liquid probe, the first aim of this work is to determine the “macroscopic pKa values” of the SC, both in vitro and in vivo. Consequently, dynamic contact angles are measured between test-liquid drops (aqueous solutions ranging from pH 1 to pH 13) and the SC in order to obtain the contact angle titration curve of the SC. The same procedure is applied in vivo on SC suffering from skin dryness (xerosis), the results being compared to those obtained previously on safe skin. The second purpose of this study is to reach the pKa values of the different functional groups located on the complex-cornified envelope. This consists in measuring adhesion forces between an AFM (Atomic Force Microscopy) tip (functionalized with specific groups, such as amine, carboxylic acid, hydroxyl, methyl or amide groups) and single-isolated corneocytes through buffered liquid media (ranging from pH 1 to pH 13). As previously, such titration curves are realised on corneocytes coming from safe skin, but also from dry skin. The variations observed in the contact angle titration and chemical force titration curves will be discussed in terms of acid-base, electrostatic interactions and hydrogen bondings. The comprehension of the pH-dependent properties of the SC shall provide a better understanding of the role of individual corneocytes in the final surface properties of the SC.

This thesis focuses on the mining of cryptocurrency with emphasis on analysis of communication between miner and server. It describes basic principles of cryptocurrencies, mining and employed communication protocols. The next part of thesis is about design and implement modification of existing system (catalogue). This modification will add temporality to the catalog, what increase reliability of stored metadata. Description, functionality and purpose of existing system is included in the next text.

Orientador: Veridiana de Lara Weiser Bramante / Resumo: O Cerrado é considerado um dos 25 hotspots mundiais, uma das áreas prioritárias para a conservação da biodiversidade mundial, por apresentar uma alta biodiversidade, um alto grau de endemismo e suas espécies estarem ameaçadas de extinção. Sendo assim, é fundamental o desenvolvimento de estudos na vegetação de cerrado para subsidiar trabalhos de conservação, manejo e restauração ecológica. O presente estudo visou conhecer as espécies que constituem o estrato de regeneração natural de uma área de cerradão na Gleba II do Refúgio de Vida Florestal Aimorés, em Bauru, centro-oeste do estado de São Paulo, sudeste do Brasil. Por meio do método de parcelas, realizamos o inventário da regeneração natural em duas classes de altura. A classe I (H ≤ 50 cm), chamamos de banco de plântulas e amostramos em subparcelas de 2 m x 2 m e a classe II (50 cm < H ≤ 1 m) chamamos de jovens regenerantes, amostramos em subparcelas de 5 m x 5 m. Alocamos as duas subparcelas no canto inferior esquerdo de 25 parcelas permanentes de 10 m x 10 m. Para cada classe de altura da regeneração natural analisamos os parâmetros de riqueza e abundância, calculamos o índice de diversidade de Shannon (H’) e equabilidade (J), os índices de regeneração natural por classe (RNC) e total (RNT).Utilizamos o índice de Sorensen para avaliar a similaridade florística entre as classes de altura da regeneração natural e entre a regeneração natural como um todo e o estrato arbóreo amostrado em dois períodos, 2005 e 2019. Amostram... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The Cerrado is considered one of the 25 hotspots, one of the priority areas for the conservation of global biodiversity, as it presents a high biodiversity, a high degree of endemism and its species are threatened with extinction. Therefore, it is essential to develop studies in the cerrado vegetation to support conservation, management and ecological restoration work. The present study aimed to know the species that constitute the natural regeneration stratum of woodland cerrado area in the Wildlife Refuge Aimorés, in Bauru, middle west of the state of São Paulo, southeastern Brazil. Using the plot method, we carried out the inventory of natural regeneration in two height classes. Class I (H ≤ 50 cm), we call the seedling bank and sample in subplots of 2 m x 2 m and class II (50 cm <H ≤ 1 m), young regenerators, we sample in sub plots of 5 m x 5 m. We allocated the two subplots in the lower left corner of 25 permanent plots of 10 m x 10 m. For each height class of natural regeneration, we analyzed the parameters of species richness and abundance, calculating the Shannon diversity index (H') and equability (J), the natural regeneration indices by class (RNC) and total (RNT). We used the Sorensen index to assess the floristic similarity between the height classes of natural regeneration and between natural regeneration and the tree strata sampled in two periods, 2005 and 2019. We sampled 617 individuals from the seedling bank, belonging to 44 species and 680 young regenerating... (Complete abstract click electronic access below) / Mestre

Erhöhte Hautoberflächen-pH-Werte werden bei atopischer Dermatitis beobachtet.Störungen der pH-Regulation, insbesondere eine unzureichende Azidifizierug des Stratum corneum, werden mit der Störung der epidermalen Barrierefunktion bei atopischer Dermatitis als pathogenetischer Faktor diskutiert.Zielsetzung der vorliegenden Arbeit war die Klärung der Frage, ob Störungen der pH-Regulation schon unmittelbar im Verlauf der postpartalen Phase bei Neugeborenen nachweisbar sind. Ferner sollte geklärt werden, ob der Hautoberflächen-pH-Wert als Prädiktor der atopischen Dermatitis herangezogen werden kann.Es wurden 108 Säuglinge der Entbindungsstation des Städtischen Klinikums Gütersloh im postpartalen Verlauf (4 bis 7 Tage,sowie 6, 12 und 24 Wochen nach der Geburt) mittels Hautoberflächen-pH-Messung und Corneometrie (24 Woche postpartum) untersucht. Es wird gezeigt, dass der Hautoberflächen-pH-Wert atopisch disponierter Säuglinge und von Säuglingen ohne atopische Disposition keinen signifikanten Unterschied im postpartalen Verlauf aufweist.Dagegen zeigten atopisch disponierte Säuglinge einen deutlich niedrigeren Wert der Stratum-corneum-Hydratation (Corneometrie). Die Ergebnise lassen den Schluß zu, dass der Barrierefunktionsstörung der atopischen Dermatitis keine primäre pH-Regulationsstörung zugrunde liegt. Die Messung der Hautoberflächen-pH eignet sich nicht zur Früherkennung der atopischen Dermatitis.

Объект исследования: дискурс элитарных средств информации (от англ. elite media ― термин, зафиксированный в англоязычной специальной литературе (Jamieson 1992). В работе исследуются три «отдельных случая» (case studies), три разных по объему содержательных пространства таких языковых знаков как статья газетного издания, рубрика журнала и отдельный выпуск издания. А именно: одна из статей, опубликованных в воскресном приложении «Domenica» к газетному итальянскому изданию «Il Sole 24 Ore»); одна из рубрик англоязычного журнала «Harvard Business Review»); один из выпусков англоязычного журнала «The Lion»). "Harvard Business Review" — самое авторитетное англоязычное журнальное издание по менеджменту [www.harvardbusinessreview.com]. "Il Sole 24 Ore" — влиятельное политико-финансово-правовое газетное издание Италии [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. Выбор журнала "The Lion" дополняет выборку исследования и является международным клубным журнальным изданием закрытого типа, распространяемое по подписке исключительно среди членов клуба (Lions Club International – самая крупная элитарная благотворительная организация в мире). Методологическая основа исследования: каузально-генетическая теория, репрезентирующая белорусскую школу дискурс-анализа (см. работы Ухвановой-Шмыговой, Поповой, Маркович, Савич, Курчак). Каузально-генетическая теория ориентирована на изучение функционального многопланового содержания сложных языковых знаков; включает в ядро содержания... [полный текст, см. далее] / Tyrimo objektas: elitinės žiniasklaidos diskursas (elite media – terminas, vartojamas anglų literatūroje (Jamieson 1992)). Darbe nagrinėjami trys „atskiri atvejai“ (case studies), trys skirtingo dydžio turiningos kalbos ženklų erdvės – laikraštinio leidinio straipsnis, žurnalo rubrika ir atskiras leidinio leidimas. Tai yra: vienas iš straipsnių, išspausdintų italų leidinio „Il Sole 24 Ore“ sekmadieniniame priede „Domenica“; viena iš angliško žurnalo „Harvard Business Review“ rubrikų; vienas iš angliško žurnalo „The Lion“ leidimų. „Harvard Business Review” – pats autoritetingiausias angliškas žurnalas apie vadybą [www.harvardbusinessreview.com]. „Il Sole 24 Ore“ – įtakingas politinis, finansinis ir teisinis Italijos laikraštis [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. Pasirenkant žurnalą „The Lion” buvo papildyta tyrimo medžiaga – tai klubinis uždaro tipo žurnalinis leidinys, platinamas pagal prenumeratą tik klubo nariams (Lions Club International – didžiausia pasaulio elitinė labdaros organizacija). Tyrimo metodologinis pagrindas: kauzalinė-genetinė teorija, reprezentuojanti baltarusių diskurso analizės mokyklą (žr. Uchvanovos-Šmygovos, Popovos, Markovič, Savič, Kurčiak darbus). Kauzalinė-genetinė teorija skirta tyrinėti sudėtingų kalbos ženklų daugiaplanį funkcinį turinį; pagal ją turinio branduoliui priklauso referentinė (informacija apie bendravimo dalyką) ir kortežinė (informacija apie komunikacijos dalyvius – bendravimo kortežą), ženklinė-referentinė ir... [toliau žr. visą tekstą] / Discourse of elite media is my research field. Elite media define outlets or programmes having a (inter)national impact, although their audience may be relatively small and geographically limited; these media are opinion leaders; they are an elite group that affects the decisions made in other media (Jamieson, Kathleen Hall 1992). There are three case studies covered in the research paper. The case studies are based on different in size and volume printed elite media texts, and they are: one of the articles published in the Sunday Supplement Domenica to Italian newspaper Il Sole 24 Ore; one of the sections published in the Harvard Business Review magazine; one of the issues of The Lion magazine. The Harvard Business Review is pre-eminent in the financial and top-management community [www.harvardbusinessreview.com]. The Il Sole 24 Ore is considered to be a professional setter of standards in Italy; it is trusted, respected, and used by other journalists [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. The Lion magazine is an international club magazine and is distributed on subscription basis exclusively among members of the Lions Club International which is the largest elite charity organization in the world. Causal-genetic theory representing Belarusian school of discourse-analysis is a core methodology used in my research (Oukhvanova, Popova, Markovich, Savich, Kurchak). Causal-genetic theory (hereinafter CGTh) is a contribution to the study of functional and... [to full text]

Discourse of elite media is my research field. Elite media define outlets or programmes having a (inter)national impact, although their audience may be relatively small and geographically limited; these media are opinion leaders; they are an elite group that affects the decisions made in other media (Jamieson, Kathleen Hall 1992). There are three case studies covered in the research paper. The case studies are based on different in size and volume printed elite media texts, and they are: one of the articles published in the Sunday Supplement Domenica to Italian newspaper Il Sole 24 Ore; one of the sections published in the Harvard Business Review magazine; one of the issues of The Lion magazine. The Harvard Business Review is pre-eminent in the financial and top-management community [www.harvardbusinessreview.com]. The Il Sole 24 Ore is considered to be a professional setter of standards in Italy; it is trusted, respected, and used by other journalists [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. The Lion magazine is an international club magazine and is distributed on subscription basis exclusively among members of the Lions Club International which is the largest elite charity organization in the world. Causal-genetic theory representing Belarusian school of discourse-analysis is a core methodology used in my research (Oukhvanova, Popova, Markovich, Savich, Kurchak). Causal-genetic theory (hereinafter CGTh) is a contribution to the study of functional and... [to full text] / Tyrimo objektas: elitinės žiniasklaidos diskursas (elite media – terminas, vartojamas anglų literatūroje (Jamieson 1992)). Darbe nagrinėjami trys „atskiri atvejai“ (case studies), trys skirtingo dydžio turiningos kalbos ženklų erdvės – laikraštinio leidinio straipsnis, žurnalo rubrika ir atskiras leidinio leidimas. Tai yra: vienas iš straipsnių, išspausdintų italų leidinio „Il Sole 24 Ore“ sekmadieniniame priede „Domenica“; viena iš angliško žurnalo „Harvard Business Review“ rubrikų; vienas iš angliško žurnalo „The Lion“ leidimų. „Harvard Business Review” – pats autoritetingiausias angliškas žurnalas apie vadybą [www.harvardbusinessreview.com]. „Il Sole 24 Ore“ – įtakingas politinis, finansinis ir teisinis Italijos laikraštis [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. Pasirenkant žurnalą „The Lion” buvo papildyta tyrimo medžiaga – tai klubinis uždaro tipo žurnalinis leidinys, platinamas pagal prenumeratą tik klubo nariams (Lions Club International – didžiausia pasaulio elitinė labdaros organizacija). Tyrimo metodologinis pagrindas: kauzalinė-genetinė teorija, reprezentuojanti baltarusių diskurso analizės mokyklą (žr. Uchvanovos-Šmygovos, Popovos, Markovič, Savič, Kurčiak darbus). Kauzalinė-genetinė teorija skirta tyrinėti sudėtingų kalbos ženklų daugiaplanį funkcinį turinį; pagal ją turinio branduoliui priklauso referentinė (informacija apie bendravimo dalyką) ir kortežinė (informacija apie komunikacijos dalyvius – bendravimo kortežą), ženklinė-referentinė ir... [toliau žr. visą tekstą] / Объект исследования: дискурс элитарных средств информации (от англ. elite media ― термин, зафиксированный в англоязычной специальной литературе (Jamieson 1992). В работе исследуются три «отдельных случая» (case studies), три разных по объему содержательных пространства таких языковых знаков как статья газетного издания, рубрика журнала и отдельный выпуск издания. А именно: одна из статей, опубликованных в воскресном приложении «Domenica» к газетному итальянскому изданию «Il Sole 24 Ore»); одна из рубрик англоязычного журнала «Harvard Business Review»); один из выпусков англоязычного журнала «The Lion»). "Harvard Business Review" — самое авторитетное англоязычное журнальное издание по менеджменту [www.harvardbusinessreview.com]. "Il Sole 24 Ore" — влиятельное политико-финансово-правовое газетное издание Италии [www.giornalilocali.it/quotidiani/il-sole-24-ore.htm]. Выбор журнала "The Lion" дополняет выборку исследования и является международным клубным журнальным изданием закрытого типа, распространяемое по подписке исключительно среди членов клуба (Lions Club International – самая крупная элитарная благотворительная организация в мире). Методологическая основа исследования: каузально-генетическая теория, репрезентирующая белорусскую школу дискурс-анализа (см. работы Ухвановой-Шмыговой, Поповой, Маркович, Савич, Курчак). Каузально-генетическая теория ориентирована на изучение функционального многопланового содержания сложных языковых знаков; включает в ядро содержания... [полный текст, см. далее]