Made available in DSpace on 2014-12-17T15:38:43Z (GMT). No. of bitstreams: 1 AlexRA.pdf: 567074 bytes, checksum: 3a5ebacebe919f714caca1b9d3cbff94 (MD5) Previous issue date: 2004-12-20 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / Psychiatric reform occurring in Brazil has progressed significantly during the last two decades, both in the transformation of the help structure and in the treatment of madness. At the same time a paralell movement is observed marked by the maintenance of the hospital centered or psychiatric ward ideology present not only in the psychiatric institutions but also in the substitute services in the cities and , above all, in the ways of contemporary subjectivation. We affirm that the idea of deinstitutionalization is intertwined with capitalistic agent both from the epistomological, assistance, and legal aspect as from the cultural one. This work aims mainly to discuss madness and subjectivity from the ethic esthetic-political perspective, specially the wishes of the psychiatric hospital, which we inhabit and who inhibits our interactions and our desired and creative productivity. We do also want to access the invisible threads that capture and modify madness, which make our cities a means for the production of pathologies, and those that, on the contrary, insinuate a process of resistance, facilitating life and health / O processo de Reforma Psiqui?trica em curso no pa?s vem avan?ando significativamente ao longo das duas ?ltimas d?cadas no que diz respeito ? transforma??o da estrutura asilar e das pr?ticas de cuidado para com a loucura. Por?m, observa-se que, paralelamente a esse movimento, h? um outro marcado pela manuten??o da l?gica hospitaloc?ntrica ou manicomial, presente n?o s? no interior das institui??es psiqui?tricas, mas nos servi?os substitutivos, nas cidades e, sobretudo, nos modos de subjetiva??o contempor?neos. Dir?amos que o ide?rio da desinstitucionaliza??o ? atravessado por um agenciamento do tipo "capital?stico" tanto do ponto de vista epistemol?gico, assistencial e jur?dico, quanto cultural. Esse trabalho visa, dentre outras coisas, discutir loucura e subjetividade numa perspectiva ?tico-est?tica-pol?tica, especialmente sobre os "desejos de manic?mio" que nos habitam e que obstruem nossa pot?ncia de agir, nossa produ??o desejante e criadora. De outro modo, queremos acessar as malhas invis?veis que capturam e mortificam a loucura, que fazem das cidades um dispositivo de produ??o de patologias e, aquelas redes que, contrariamente, insinuam processos de resist?ncia, possibilitam a inven??o da vida e da sa?de

Made available in DSpace on 2014-12-17T15:38:46Z (GMT). No. of bitstreams: 1 AnaKS.pdf: 949155 bytes, checksum: 510b8189ff7d40e57f75385d069921bc (MD5) Previous issue date: 2009-06-26 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / The research objective is explore practices to mutual help between CAPS users from the east and west regions of the city of Natal, RN, in Brazil. In the mental health field, we observe the care from substitutive services is based on technical knowledge where the person of the mental health professional is predominant. The Brazilian psychiatry reform invests in equipments and mental health care protocols, but it is necessary to invest more vigorously in new strategies and actors capable of obtaining resources to achieve this goal, such as the users. If one cornerstone of the psychiatric reform consists of changing the type of relationship established with the person with mental disorders, why this relationship, nowadays, is still dominated by technique and unevenness, where on one side we have a person who knows something and who needs take care of someone, and on other side we have another who knows nothing and thus needs to be cared for? Starting from this problematization of the traditional methods of health/mental health care, an attempt was made to investigate in what ways the mutual help practices between people with mental disorders can realize potential avenues not yet explored within the scope of psychiatric reform. The objective of this research was to map possible mutual help practices among the users, and the technical understanding of such practices. For that, we took part in the daily activities of the CAPS, mapping the experiences of mutual help among users. In addition, we accompanied the users in external activities (such as return home, trips, etc), and we had roundtables with the professionals. The research was guided by theoretical methodological references of the institutional analysis. The results pointed to a lack of behaviors of mutual help or support among users, something that can probably be explained by the service work dynamics, as well as the relationship between technicians and users, which has a tendency to create hurdles for meetings among users, as well as being non-conducive to theirempowerment / Essa pesquisa objetivou investigar pr?ticas de ajuda m?tua entre usu?rios dos CAPS leste e oeste da cidade de Natal-RN. No campo da sa?de mental, observamos que o cuidado proporcionado pelos servi?os substitutivos tende a ser pautado pelo saber t?cnico onde a figura do profissional predomina. A reforma psiqui?trica brasileira tem investido em equipamentos e pol?ticas de aten??o em sa?de mental, mas ? preciso investir mais fortemente em novas estrat?gias e atores capazes de agenciar for?as instituintes a esse movimento, tais como os usu?rios. Se um dos eixos da reforma psiqui?trica consiste em uma mudan?a no tipo de rela??o que se estabelece com o portador de transtorno mental, porque essa rela??o, nos dias de hoje, ainda se configura de maneira t?cnica e desigual, onde de um lado h? um sujeito que sabe e deve cuidar e de outro um que nada sabe, devendo, portanto, ser cuidado? Partindo dessa problematiza??o acerca dos modos tradicionais de cuidado em sa?de/sa?de mental, buscou-se investigar de que maneira as pr?ticas de ajuda m?tua entre portadores de transtorno mental podem agenciar potencialidades ainda n?o exploradas no ?mbito da reforma psiqui?trica. O objetivo da pesquisa foi mapear poss?veis pr?ticas de ajuda entre os usu?rios, bem como a concep??o dos t?cnicos sobre tais pr?ticas. Para isso, participamos cotidianamente das atividades desenvolvidas nos CAPS, mapeando as experi?ncias de ajuda entre os usu?rios. Al?m disso, acompanhamos os usu?rios nos ambientes extra-servi?os (volta para casa, passeios, etc.), e realizamos rodas de conversa com os profissionais. A pesquisa foi orientada pelo referencial te?rico-metodol?gico da an?lise institucional. Os resultados apontaram para uma falta de atitudes de ajuda ou suporte m?tuo entre usu?rios, provavelmente explicado pela din?mica de funcionamento do servi?o e pela rela??o entre t?cnicos e usu?rios, que tende a dificultar encontros entre usu?rios, al?m de n?o favorecerem o empoderamento dos mesmos.

Made available in DSpace on 2014-12-17T15:38:51Z (GMT). No. of bitstreams: 1 DanielleFG_DISSERT.pdf: 5162066 bytes, checksum: d43c54235f8f5b351fac7f8338c0b332 (MD5) Previous issue date: 2011-04-01 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / Central Nervous System are the most common pediatric solid tumors. 60% of these tumors arise in posterior fossa, mainly in cerebellum. The first therapeutic approach is surgical resection. Malignant tumors require additional strategies - chemotherapy and radiotherapy. The increasing survival evidences that childhood brain tumors result in academic and social difficulties that compromise the quality of life of the patients. This study investigated the intellectual functioning of children between 7 to 15 years diagnosed with posterior fossa tumors and treated at CEHOPE - Recife / PE. 21 children were eligible - including 13 children with pilocytic astrocytoma (G1) who underwent only surgery resection, and eight children with medulloblastoma (G2) - submitted to surgical resection, chemotherapy and craniospinal radiotherapy. Participants were evaluated by the Wechsler Intelligence Scale for Children - WISC-III. Children of G1 scored better than children of G2. Inferential tools (Mann-Whitney ? Test) identified significant diferences (p ≤ 0.05) between the Performance IQ (PIQ) and Processing Speed Index (PSI) as a function of treatment modality; Full Scale IQ (FSIQ), PIQ and PSI as a function of parental educational level; PIQ, FSIQ, IVP and Freedom from Distractibility (FDI) as a function of time between diagnosis and evaluation. These results showed the late and progressive impact of radiotherapy on white matter and information processing speed. Furthermore, children whose parents have higher educational level showed better intellectual performance, indicating the influence of xxii socio-cultural variables on cognitive development. The impact of cancer and its treatment on cognitive development and learning should not be underestimated. These results support the need to increase the understanding of such effects in order to propose therapeutic strategies which ensure that, in addition to the cure, the full development of children with this pathology / Os tumores de Sistema Nervoso Central s?o as neoplasias s?lidas mais frequentes na inf?ncia. 60% desses tumores ocorrem na fossa posterior, cujo principal componente ? o cerebelo. A primeira interven??o ? a ressec??o cir?rgica; tumores malignos requerem estrat?gias terap?uticas complementares quimioterapia e radioterapia. O aumento da sobrevida evidenciou que crian?as com tumores cerebrais apresentam dificuldades acad?mico-sociais que comprometem sua qualidade de vida. O objetivo deste estudo foi investigar a capacidade intelectiva de crian?as de 6 a 16 anos com tumores de fossa posterior. Participaram 21 crian?as atendidas pelo CEHOPE Recife/PE sendo 13 crian?as com astrocitoma piloc?tico (G1) - submetidas ? cirurgia de ressec??o e; oito crian?as com meduloblastoma (G2) submetidas a cirurgia de ressec??o, quimioterapia e radioterapia de cr?nio e neuro-eixo. Os participantes foram avaliados pelas Escalas Wechsler de Intelig?ncia para Crian?as WISC-III. Crian?as de G1 obtiveram desempenho superior ao de crian?as de G2. An?lises estat?sticas inferenciais (Teste ? de Mann-Whitney) identificaram contrastes estatisticamente significativos (p≤0,05), entre o QI de Execu??o (QIE) e ?ndice Fatorial Velocidade de Processamento (IVP) em fun??o da modalidade de tratamento; QI Total, QIE e IVP em fun??o do n?vel de escolaridade dos pais; QIE, QIT, IVP e ?ndice Fatorial Resist?ncia ? Distra??o (IRD) em fun??o do tempo entre o diagn?stico e a avalia??o. Sugere-se o impacto tardio e progressivo da radioterapia sobre a subst?ncia branca e sobre a velocidade de processamento; crian?as cujos pais possuem maior n?vel de instru??o formal apresentam melhor capacidade intelectiva, sugerindo a influ?ncia de vari?veis s?cio-culturais sobre o desenvolvimento cognitivo. O impacto do c?ncer e seu tratamento sobre o desenvolvimento e a aprendizagem n?o deve ser subestimado. Tais resultados refor?am a necessidade de aprofundar a compreens?o sobre tais efeitos, visando propor estrat?gias terap?uticas que garantam, al?m da reabilita??o cl?nica, o pleno desenvolvimento das crian?as com esta patologia.

Made available in DSpace on 2014-12-17T15:38:52Z (GMT). No. of bitstreams: 1 EdianaROG_DISSERT.pdf: 2182777 bytes, checksum: a6c802e96d340606dfb3cbb335b79787 (MD5) Previous issue date: 2011-04-01 / The present work investigated the cognitive operation of children diagnosed with acute lymphoblastic leukaemia (ALL), accompanied at pediatric oncologic institutions at the city of Natal/RN. Had participated in this study twenty children, of both sexes, between six and twelve years old, with the ALL diagnostic, who were in treatment (n=10) and out of treatment for at least one year (n=10) and were submitted exclusively to chemotherapy as CNS prophylaxis. The utilized protocol of neuropsychological evaluation covered the following cognitive abilities: intellective capability, attentional and memory systems, and executive functions. Data was analyzed through descriptive and inferential measures, with the support of the Mann-Whitney U Test and T-test, considering the influence of the variables sex, age at diagnostic and the past time since the beginning of the treatment over children s performance. The intellective capability evaluation showed low score to the out-of-treatment groups, female and children under five years old to the diagnostic. In concern of attentional systems, groups showed the expected performance. In a relevant way, in the evaluation of executive functions, were found reduced scores within all groups, especially inside the in-treatment group. Memory evaluation pointed to reduced performance in items concerning to learning evolution and spontaneous evocation after interference to the several groups. It can be concluded, reffer to the occurrence of transitory and permanent impact associated to the intrusion of chemotherapic components during the maturational course of the CNS. It s expected that the present investigation and the development of similar studies enable major comprehension about the mode, extension and repercussion of these damages subsidizing the development of strategies which may minimize them and provide better xxiii life quality to this clinical subgroup / O presente trabalho investigou o funcionamento cognitivo de crian?as diagnosticadas com Leucemia Linf?ide Aguda (LLA) acompanhadas por institui??es oncol?gicas pedi?tricas no munic?pio de Natal/RN. Participaram deste estudo 20 crian?as diagnosticadas com LLA, de ambos os sexos, com idades entre seis e doze anos, que estavam em tratamento (n=10) e fora de tratamento h? pelo menos 1 ano (n=10), submetidas exclusivamente ? quimioterapia como profilaxia do SNC. O protocolo de avalia??o neuropsicol?gica utilizado contemplou as seguintes habilidades cognitivas: capacidade intelectiva, sistemas atencionais e de mem?ria e fun??es executivas. Os dados foram analisados atrav?s de medidas descritivas e inferenciais com o aux?lio do Teste U de Mann-Whitney e do Teste t, considerando-se a influ?ncia das vari?veis sexo, idade ao diagn?stico e tempo decorrido desde o in?cio do tratamento sobre o desempenho das crian?as. A avalia??o da capacidade intelectiva revelou baixas pontua??es para os grupos fora de tratamento, sexo feminino e crian?as menores de cinco anos ao diagn?stico. Quanto aos sistemas atencionais os grupos apresentaram desempenho dentro do esperado. De forma relevante, na avalia??o das fun??es executivas foram encontradas pontua??es reduzidas em todos os grupos, com destaque para o grupo em tratamento. A avalia??o da mem?ria indicou desempenho rebaixado em itens concernentes ? evolu??o da aprendizagem e evoca??o espont?nea ap?s interfer?ncia para os diversos grupos. Conclui-se que estas informa??es aludem ? ocorr?ncia de impactos transit?rios e permanentes associados ? intrus?o de componentes quimioter?picos no curso maturacional do SNC. Espera-se que a presente investiga??o e o desenvolvimento de estudos semelhantes possibilitem maior compreens?o acerca da modalidade, extens?o e repercuss?o de tais preju?zos, subsidiando o desenvolvimento de xxi estrat?gias que possam minimiz?-los e proporcionar maior qualidade de vida para este subgrupo cl?nico

Made available in DSpace on 2014-12-17T15:39:01Z (GMT). No. of bitstreams: 1 AriadneC.pdf: 385711 bytes, checksum: dcc828db10778b9bff5343cd3bed9087 (MD5) Previous issue date: 2006-09-22 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / The purpose of this study is to discuss the therapeutic workshops function, while questioning if they constitute a mechanism for change of the traditional asylum logic. The Psychiatric Reform was materialized with the financing and regulation of alternative services that substitute the psychiatric hospital. This change was promoted by the anti asylum debate and the deinstitutionalization besides psychosocial rehabilitation paradigms. Mental health care, therefore, acquired a new form and the Centers for Psychosocial Care (CAPS) are considered the main services of the health network presently under construction. They are services that offer a variety of therapeutics and amongst them is the workshop, considered essential for the advancement of the Reform ideas. The study was conducted in a CAPS II in Natal, RN. Systematic visits were made using the Institutional Analysis perspective, futhermore were made interviews with professionals who was related to workshops. In the end, data were then discussed according to Schizoanalysis. Results denot that workshops represents, in the same time, progress and regress of Psychiatric Reform. It was observed that workshops were oftentimes reduced to strategies for the occupation of time, and as a means for the transmission of social values considered correct. The relationship between professionals and the user of the service was hierarchical and both players was seeing the workshop as a task to be met. Although users expressed intreresting about wokshops, was reported that the work was boring. Besides, except for some cases, the therapeutic workshops wasn t helping clients to create other possibilites in theirs life and stops the job inside the mental care service / Este trabalho objetivou investigar as oficinas terap?uticas num servi?o substitutivo ao hospital psiqui?trico, observando se seu funcionamento condiz ou n?o com preceitos da Reforma Psiqui?trica. Esta, tendo sido fomentada pela luta antimanicomial e embasada pela desinstitucionaliza??o e pela reabilita??o psicossocial, materializou-se com o financiamento e regulamenta??o de servi?os substitutivos ao manic?mio. Desde ent?o, novas formas de cuidado se configuram e os Centros de Aten??o Psicossocial (CAPS) s?o um dos principais servi?os da nova rede de sa?de. Os CAPS s?o servi?os abertos que oferecem uma variada gama de terap?uticas, dentre elas, destacam-se as oficinas terap?uticas: estrat?gias fundamentais por serem consideradas o baluarte dos novos servi?os. A coleta de dados ocorreu num CAPS II, em Natal-RN, onde foram realizadas visitas sistem?ticas orientadas pela An?lise Institucional, al?m de entrevistas com os funcion?rios que se encontravam ligados ao exerc?cio das oficinas. Os dados foram discutidos ? luz da Esquizoan?lise, revelando que o funcionamento das oficinas traduzem avan?os e retrocessos da Reforma. Notou-se que as oficinas eram espa?os onde alguns preconceitos eram desconstru?dos, auxiliando os usu?rios no estabelecimento de novas rela??es consigo, com outros e com o mundo. Entretanto, tamb?m foi observado que muitas vezes as oficinas se reduziam a meras estrat?gias de ocupa??o do tempo e serviam de ve?culo de transmiss?o de valores socialmente legitimados como certos. Percebeu-se que a rela??o entre profissionais e usu?rios era hierarquizada e que, por vezes, ambos viam a oficina como uma tarefa a ser cumprida. Da mesma forma, foi notado que os usu?rios, concomitantemente, mantinham um discurso de interesse pelas oficinas e expressavam que elas eram repetitivas e enfadonhas. J? a equipe t?cnica mantinha o discurso da luta antimanicomial, mas n?o conseguia sustent?-lo nas suas pr?ticas cotidianas. Al?m disso, afora exce??es, as oficinas eram espa?os que n?o possibilitam a cria??o e conservam o servi?o fechado em si mesmo

Made available in DSpace on 2014-12-17T15:42:06Z (GMT). No. of bitstreams: 1 JoaoBAF_DISSERT.pdf: 2926590 bytes, checksum: 284a772c6dacfa2a7184d7f4569c6cab (MD5) Previous issue date: 2011-03-11 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / Although there are many studies on urban dust contamination by heavy metals in developed countries, little attention has been paid to this type of study in developing countries, including Brazil. Therefore, a series of investigations were performed to provide signatures of heavy metals in urban dust and assess the potential sources in the city of Natal - RN-Brazil. The fraction of these sediments was studied to pass through a sieve of 63 micrometers. For the study analyzed two groups of samples, one collected in September 2009 at the end of the rainy season (9 samples) and one collected in January 2010 in the dry season (21 samples). So in all, thirty sediment samples were collected from the street. Then, in Fluorescence Spectrometry X-rays were determined major elements SiO2, Na2O, K2O, Al2O3, MgO, P2O5, Fe2O3, MnO, TiO2 and CaO, and trace Rb, Cr, Ni, Cu, Zn, Sr and Pb by an ICPOES was determined Zn, V, Na, K, Ni, Mn, Mg, P, Fe, Cr, Cu, Pb, Ba, Ca and Al from leaching HCl 0.5 mol L-1 . The results of the concentrations of elements show that the greater presence of these occurs in the dry season, except for Si which is higher in the rainy season. Analyses by geoaccumulation Index (IGEO) Enrichment Factor (EF), Contamination Factor (CF), analysis correlation and Hierarchical Cluster, confirm that Zn, Cu and Pb is anthropogenic character. Zinc may be derived from various sources related to motor vehicles or the road signs and street grids. The elements Na, K, Mg and Ca may be related to droplets suspended in air containing cations and anions present in seawater (salty), common in Christmas throughout the year, brought by winds SE-NW. The elements Na, Mg, Ca and K are the most abundant in seawater and were analyzed in this study. This indicates that the source of these additional elements detected by analyzing the contamination factor may be the very sea. Moreover, Ni, Fe, Cr and Ba can be either as a source of anthropogenic geog?nica. The source of Ca is different, because it comes in lime and paint (painting guides of buildings and streets) in construction materials, but may also be present in sediments in the fragments of shells or carbonate bioclasts common in the coastal area / Embora existam muitos estudos sobre a contamina??o de poeiras urbanas por metais pesados nos pa?ses desenvolvidos, pouca aten??o tem sido dada a este tipo de estudo nos pa?ses em desenvolvimento, incluindo o Brasil. Portanto, uma s?rie de investiga??es foram realizadas para fornecer assinaturas de metais pesados em poeiras urbanas e avaliar as fontes potenciais na cidade do Natal RN-Brasil. A fra??o estudada destes sedimentos foi a passante na peneira de 63 μm. Para o estudo foram analisados dois grupos de amostras, sendo um coletado no m?s de setembro de 2009 no final da esta??o chuvosa (9 amostras) e outro coletado no m?s de janeiro de 2010 no final da esta??o seca (21 amostras). Portanto ao todo, trinta amostras de sedimentos de rua foram coletadas. Em seguida, por Espectrometria de Fluoresc?ncia de raios X foram determinados os elementos maiores SiO2, Na2O, K2O, Al2O3, MgO, P2O5, Fe2O3, MnO, TiO2 e CaO e tra?os Rb, Cr, Ni, Cu, Zn, Sr e Pb. Pela t?cnica de ICP-OES foram determinados Zn, V, Na, K, Ni, Mn, Mg, P, Fe, Cr, Cu, Pb, Ca, Ba e Al a partir de lixivia??o a HCl 0,5 mol L-1. Os resultados das concentra??es dos elementos mostram que a maior presen?a desses ocorre na esta??o seca, com exce??o para o Si que ? maior na esta??o chuvosa. As an?lises por ?ndice de Geoacumula??o (IGeo), Fator de Enriquecimento (FE), Fator de Contamina??o (FC), an?lises de correla??o e agrupamentos, confirmam que Zn, Cu e Pb tem car?ter antropog?nico. O Zn pode ser proveniente de fontes diversas relacionados aos ve?culos automotores ou ?s placas de sinaliza??o e grades das ruas. Os elementos Na, K, Mg e Ca podem estar relacionados ?s got?culas de ar que cont?m em suspens?o os c?tions e ?nions presentes na ?gua do mar (maresia), comum em Natal durante todo o ano, trazida pelos ventos SE-NW. Os elementos Na, Mg, Ca e K s?o os mais abundantes na ?gua do mar e foram analisados no presente trabalho. Isto indica que a fonte adicional destes elementos detectada atrav?s da an?lise do fator de contamina??o pode ser a pr?pria maresia. Por outro lado, Ni, Fe, Cr e Ba podem ser tanto de origem antropog?nica como de origem geog?nica. A fonte do Ca ? diversa, pois este entra na cal e tintas (pintura de edifica??es e guias de ruas), nos materiais de constru??o civil, mas pode estar tamb?m presente nos sedimentos nos fragmentos de conchas ou bioclastos carbon?ticos comuns na ?rea litor?nea

Submitted by PPG Ci?ncia da Computa??o (ppgcc@pucrs.br) on 2018-09-03T14:00:58Z No. of bitstreams: 1 RAFAEL CAUDURO OLIVEIRA MACEDO_DIS.pdf: 6178948 bytes, checksum: 6ed3599e31f122e78b11b322a8c0ac06 (MD5) / Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2018-09-04T12:17:04Z (GMT) No. of bitstreams: 1 RAFAEL CAUDURO OLIVEIRA MACEDO_DIS.pdf: 6178948 bytes, checksum: 6ed3599e31f122e78b11b322a8c0ac06 (MD5) / Made available in DSpace on 2018-09-04T12:47:15Z (GMT). No. of bitstreams: 1 RAFAEL CAUDURO OLIVEIRA MACEDO_DIS.pdf: 6178948 bytes, checksum: 6ed3599e31f122e78b11b322a8c0ac06 (MD5) Previous issue date: 2017-08-30 / Prote?nas executam um papel vital em todos os seres vivos, mediando uma s?rie de processos necess?rios para a vida. Apesar de existirem maneiras de determinar a composi??o dessas mol?culas, ainda falta-nos conhecimentos suficiente para determinar de uma maneira r?pida e barata a sua estrutura 3D, que desempenha um papel importante na suas fun??es. Um dos principais m?todos computacionais aplicados ao estudo das prote?nas e o seu processo de enovelamento, o qual determina a sua estrutura, ? Din?mica Molecular. Um aprimoramento deste m?todo, conhecido como Replica Exchange Molecular Dynamics (ou REMD), ? capaz de produzir resultados muito melhores, com o rev?s de significativamente aumentar o seu custo computacional e gerar um volume muito maior de dados. Esta disserta??o apresenta um novo m?todo de otimiza??o deste m?todo, intitulado Filtragem de Dados Anal?ticos, que tem como objetivo otimizar a an?lise p?s-simula??o filtrando as estruturas preditas insatisfat?rias atrav?s do uso de m?tricas de qualidade absolutas. A metodologia proposta tem o potencial de operar em conjunto com outras abordagens de otimiza??o e tamb?m cobrir uma ?rea ainda n?o abordada por elas. Adiante, a ferramenta SnapFi ? apresentada, a qual foi designada especialmente para o prop?sito de filtrar estruturas preditas insatisfat?rias e ainda operar em conjunto com as diferentes abordagens de otimiza??o do m?todo REMD. Um estudo foi ent?o conduzido sobre um conjunto teste de simula??es REMD de predi??o de estruturas de prote?nas afim de elucidar uma s?ries de hip?teses formuladas sobre o impacto das diferentes temperaturas na qualidade final do conjunto de estruturas preditas do processo REMD, a efici?ncia das diferentes m?tricas de qualidade absolutas e uma poss?vel configura??o de filtragem que utiliza essas m?tricas. Foi observado que as temperaturas mais altas do m?todo REMD para predi??o de estruturas de prote?nas podem ser descartadas de forma segura da an?lise posterior ao seu t?rmino e tamb?m que as m?tricas de qualidade absolutas possuem uma alta vari?ncia (em termos de qualidade) entre diferentes simula??es de predi??es de estruturas de prote?nas. Al?m disso, foi observado que diferentes configura??es de filtragem que utilize tais m?tricas carrega consigo esta vari?ncia. / Proteins perform a vital role in all living beings, mediating a series of processes necessary to life. Although we have ways to determine the composition of such molecules, we lack sufficient knowledge regarding the determination of their 3D structure in a cheap and fast manner, which plays an important role in their functions. One of the main computational methods applied to the study of proteins and their folding process, which determine its structure, is Molecular Dynamics. An enhancement of this method, known as Replica-Exchange Molecular Dynamics (or REMD) is capable of producing much better results, at the expense of a significant increase in computational costs and volume of raw data generated. This dissertation presents a novel optimization for this method, titled Analytical Data Filtering, which aims to optimize post-simulation analysis by filtering unsatisfactory predicted structures via the use of different absolute quality metrics. The proposed methodology has the potential of working together with other optimization approaches as well as covering an area still untouched at large by them to the best of the author knowledge. Further on, the SnapFi tool is presented, a tool designed specially for the purpose of filtering unsatisfactory structure predictions and also being able to work with the different optimization approaches of the Replica-Exchange Molecular Dynamics method. A study was then conducted on a test dataset of REMD protein structure prediction simulations aiming to elucidate a series of formulated hypothesis regarding the impact of the different temperatures of the REMD process in the final quality of the predicted structures, the efficiency of the different absolute quality metrics and a possible filtering configuration that take advantage of such metrics. It was observed that high temperatures may be safely discarded from post-simulation analysis of REMD protein structure prediction simulations, that absolute quality metrics posses a high variance of efficiency (regarding quality terms) between different protein structure prediction simulations and that different filtering configurations composed of such quality metrics carry on this inconvenient variance.

Made available in DSpace on 2014-12-17T15:53:14Z (GMT). No. of bitstreams: 1 AdilsonLT.pdf: 357423 bytes, checksum: 891f79b8b20c98062f6b6425fdf20178 (MD5) Previous issue date: 2006-06-09 / This work presents results derived from a study related to impact on non-controllable costs in the determination of energy taxes. This is done analyzing tax review practiced by concessionaries responsible for the distribution of electrical energy located in the Northeastern Region of Brazil, between 2003 and 2004. This Region was chosen as a study area due to the researcher s expectation in congregating companies that deliver services to markets that have similar social-economical profiles. A brief explanation related to the restructuring of the electrical sector in Brazil is presented, pointing out that there was privatization of the great majority of these companies. The study also points out the definition of regulating rules in service delivery process. The components of taxes that are practiced by these companies aimed at final consumers, as well as the market as a whole and the revision process that is executed by Ag?ncia Nacional de Energia El?trica ANEEL for the definition of these taxes are demonstrated in the research. A brief historical of the concessionaires that were focus of the research is presented, totaling five companies. Some data used by ANEEL in the tax review process was analyzed as well as data on components of approved taxes. It is concluded that as a media 47, 49% of the components of taxes in the researched companies correspond to the non-controllable costs. These is done considering previous classification by ANEEL in the tax review process. Although, if it is considered that these companies since 2006, by the means of participation in energy auctions are able to negotiate energy prices for their own needs, it is concluded that these concession contracts guarantee the delivery of the service to the costumer in the total tribute. The percentage of non-controllable costs is 16, 27% average of the tax. This means, amongst other information, that the government has a great deal of responsibility in the formation of price practiced by these companies and its target markets / Este trabalho apresenta o resultado de um estudo do impacto dos custos n?o-gerenci?veis na determina??o das tarifas de energia el?trica decorrentes do processo de revis?o tarif?ria, ocorrido nos exerc?cios de 2003 e 2004, nas concession?rias de distribui??o de energia el?trica localizadas na Regi?o Nordeste do Brasil. A escolha da Regi?o Nordeste como ?rea de estudo, deve-se ? expectativa do pesquisador em congregar no estudo empresas que prestem servi?os a mercados com perfis s?cio-econ?mico similares. ? apresentada uma breve explana??o sobre a reestrutura??o do setor el?trico no Brasil, tendo como conseq??ncia a privatiza??o da maioria das distribuidoras de energia e a defini??o das regras de regula??o na presta??o do servi?o. S?o demonstrados os componentes das tarifas de energia el?trica praticadas pelas concession?rias aos consumidores finais de seus mercados e o processo de revis?o tarif?ria executado pela Ag?ncia Nacional de Energia El?trica ANEEL para defini??o dessas tarifas. ? feito um breve hist?rico das concession?rias pesquisadas, num total de cinco companhias. Por fim, s?o discutidos os dados utilizados pela ANEEL no processo de revis?o tarif?ria e analisados os componentes das tarifas aprovadas. Conclui-se que, em m?dia, 47,49% dos componentes das tarifas das empresas pesquisadas correspondem a custos n?o-gerenci?veis, ? luz da classifica??o utilizada pela ANEEL no processo de revis?o tarif?ria. Entretanto, se considerado que as distribuidoras, a partir do exerc?cio de 2006, t?m a capacidade de negociar o pre?o de compra da energia para a totalidade de sua necessidade, participando de leil?es de energia, e que os contratos de concess?o garantem o repasse ao consumidor da totalidade dos tributos, o percentual dos custos n?o-gerenci?veis passa a ser, em m?dia, de 16,27% da tarifa, o que significa, dentre outras informa??es, que o poder p?blico tem uma consider?vel parcela de responsabilidade na forma??o dos pre?os de energia praticados pelas concession?rias em seus mercados de atua??o

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-12-04T22:25:53Z No. of bitstreams: 1 MarcosAntonioAlvesDaSilva_DISSERT.pdf: 2392478 bytes, checksum: fa9756e6692ee8e2b641c717a24729c2 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-12-11T21:16:38Z (GMT) No. of bitstreams: 1 MarcosAntonioAlvesDaSilva_DISSERT.pdf: 2392478 bytes, checksum: fa9756e6692ee8e2b641c717a24729c2 (MD5) / Made available in DSpace on 2017-12-11T21:16:38Z (GMT). No. of bitstreams: 1 MarcosAntonioAlvesDaSilva_DISSERT.pdf: 2392478 bytes, checksum: fa9756e6692ee8e2b641c717a24729c2 (MD5) Previous issue date: 2017-08-11 / ? percept?vel que, h? algum tempo, a sociedade vem passando por um processo de organiza??o da informa??o em suas pr?ticas e procedimentos, proporcionando grandes avan?os para a comunica??o e o armazenamento de dados, despertando nas institui??es p?blicas e privadas a necessidade de adapta??o e aperfei?oamento cont?nuo no tratamento de seus processos. Nesse contexto, apresenta-se uma proposta para a estrutura??o de um plano de manuten??o de equipamentos el?tricos, voltada para a manuten??o preventiva, baseada no gerenciamento da informa??o de todos os equipamentos de um sistema de distribui??o de energia el?trica. Dessa forma, partindo da an?lise das t?cnicas mais modernas de gerenciamento da manuten??o el?trica, define-se uma que melhor se enquadre na realidade do sistema el?trico de pot?ncia da Universidade Federal do Rio Grande do Norte ? UFRN, construindo-se um estudo de caso atrav?s do desenvolvimento de um sistema de gerenciamento da manuten??o baseado no cadastro de todos os seus componentes, cujo conte?do re?na os aspectos de gera??o de relat?rio de inspe??o, manuten??o preventiva e corretiva e cadastro dos dados t?cnicos dos equipamentos el?tricos, constituindo um banco de dados estruturado em ACCESS acess?vel via c?digo QR nos locais de instala??o. / It is noticeable that, for some time, society has been undergoing a process of information organization in its practices and procedures, providing significant advances for communication and data storage, raising in the public and private institutions the awareness of the need for continuous adaptation and improvement as it concerns the treatment of their processes. Within this context, we introduce a proposal to draw up an electric maintenance plan on whose stakeholders enjoy a systematic approach focused on preventive maintenance, based on the management of information of all elements of the electrical energy system. Accordingly, starting from the analysis of the most modern techniques of electric maintenance management, we can define one that better fits the reality of the electric power system of the Federal University of Rio Grande do Norte ? UFRN, thereby drawing up a case study through the development of a management system based on the registration of all its elements, whose content gathers the aspects related to the generation of inspection reports, corrective and preventive maintenance, and registration of technical data on the electric equipment, building a database structured in ACCESS accessible by means of QR code in the places where the equipment will be installed.

Made available in DSpace on 2014-12-17T14:07:04Z (GMT). No. of bitstreams: 1 ElialdoCS_TESE.pdf: 4625434 bytes, checksum: bec8d03e9004e11648c49c45f84ffe0f (MD5) Previous issue date: 2010-03-26 / Universidade Federal do Rio Grande do Norte / The dielectric porcelain is usually obtained by mixing various raw materials proportions and is used in the production of electronic equipment for various applications, from capacitors of high and low Power to insulators for low, medium, high and extra high voltage, which are used in distribution lines and transmission of electricity.This work was directed to the s tudy of technological properties of technic porcelain, made from raw materials extracted from pegmatites found in the regions of Serid? and the Alto Oeste of Rio Grande do Norte, which are made of kaolin, quartz and feldspar, abundant and high quality in these regions. The technic ceramics were obtained by mixing in appropriate levels, kaolin, feldspar, quartz and clay, the last item from a pottery in the city of Sao Gon?alo do Amarante, Rio Grande do Norte. During the development the following characterizations correlated to raw materials were made: laser particle sizing, x-ray diffraction, DTA and TG. The compositions studied were formed by uniaxial pressing at a pressure of 50 MPa and sintered at temperatures ranging from 1150 to 1350?C and levels (times) of sintering between 30, 60, 90 and 120 minutes. The characterization of the samples were taken from the analysis of weight loss, linear shrinkage, porosity, stoneware curve, bulk density, flexural strength of three points, SEM and X-ray diffraction, TMA, Dielectric and cross Resistivity. The studied materials can be employed in producing the objects used in electrical engineering such as: insulators for low, medium and high-voltage electrical systems, command devices, bushing insulation for transformers, power capacitors, spark plugs, receptacles for fluorescent and incandescent light bulbs and others / A porcelana diel?trica ? normalmente obtida atrav?s da mistura de diferentes mat?rias-primas, em propor??es adequadas, sendo utilizada na produ??o de equipamentos eletroeletr?nicos de diversas aplica??es, desde capacitores de alta e baixa pot?ncia, a isoladores para baixa, m?dia, alta e extra alta tens?o, que s?o utilizados em linhas de distribui??o e transmiss?o de energia el?trica. Neste trabalho, s?o estudadas as propriedades tecnol?gicas de uma porcelana diel?trica, formulada a partir de mat?rias-primas obtidas de pegmatitos encontrados nas regi?es do Serid? e do Alto Oeste do Rio Grande do Norte, sendo estas constitu?das de caulim, quartzo e feldspato, abundantes e de alta qualidade nestas regi?es, e de uma argila proveniente de uma cer?mica situada no munic?pio de S?o Gon?alo do Amarante, tamb?m no Estado do Rio Grande do Norte. As mat?rias-primas foram caracterizadas atrav?s de: granulometria a laser, difra??o de raios X, an?lise t?rmica diferencial e an?lise termogravim?trica. As amostras foram conformadas por prensagem uniaxial a uma press?o de 50 MPa, e sinterizadas ?s temperaturas de 1150, 1200, 1250, 1300 e 1350 ?C, com patamares de sinteriza??o de 30, 60, 90 e 120 minutos. Os ensaios tecnol?gicos realizados foram: an?lise da perda de massa, retra??o linear, porosidade, curva de gressifica??o, microscopia eletr?nica de varredura, difra??o de raios X, dilatometria, rigidez diel?trica, resistividade transversal e permissividade diel?trica. Os melhores valores de propriedades foram obtidos na temperatura de 1250 ?C, para as composi??es estudadas, n?o sofrendo varia??es significativas em seu comportamento com o tempo de sinteriza??o. Os materiais estudados podem ser empregados na obten??o de objetos usados em eletrot?cnica como por exemplo: isoladores de baixa, m?dia e alta-tens?o para redes el?tricas, dispositivos de comando, bucha de isolamento de transformador, capacitores de pot?ncia, vela de igni??o, recept?culos de l?mpadas incandescentes e fluorescentes e outros