• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 24
  • 15
  • 4
  • 3
  • 2
  • 1
  • 1
  • Tagged with
  • 83
  • 13
  • 12
  • 11
  • 11
  • 10
  • 10
  • 8
  • 8
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

Ökologische, ökonomische und soziale Nachhaltigkeit an der TU Chemnitz: Posterband mit Beiträgen aus Lehre, Forschung, Administration und von universitären Interessengruppen

Albert, Martin, Hartwig, Melanie, Hüsig, Stefan, Lanfermann, Anna 30 November 2015 (has links)
Alle Akteure der TU Chemnitz wurden 2015 dazu aufgerufen sich an einem Diskurs für Nachhaltigkeit zu beteiligen. Dazu sollten sie folgende Leitfragen beantworten: „Welche Maßnahmen und Projekte setzen Sie, als Akteur (Fakultät, Forschungsverbund, administrative Einheit, universitäre Interessensgruppe), im Rahmen der „ökologischen, ökonomischen und sozialen Nachhaltigkeit“ um? Welche Definition bzw. Konzept oder Leitbild von Nachhaltigkeit legen Sie diesen Maßnahmen und Projekten zugrunde?“ Die eingereichten Beiträge sind in diesem Posterband gesammelt.:Vorwort.........................................................................................1 Forschungsbereich Biopolymere und Naturfaserverbunde (BNF).................3 Professur Energie und Hochspannungstechnik........................................7 Professur für Innovationsforschung und Technologiemanagement.............11 Bundesexzellenzcluster MERGE..........................................................15 Professur Nachrichtentechnik der TU Chemnitz.....................................18 NATUC – Referat für Ökologie und Nachhaltigkeit...................................21 Professur Personal und Führung.........................................................24 Professur Privatrecht und Recht des geistigen Eigentums........................28 SAXEED Gründernetzwerk..................................................................32 Studentenwerk Chemnitz-Zwickau......................................................36 Universitätsbibliothek.......................................................................40 / In 2015 all agents at TU Chemnitz were called to participate in a discours on sustainability. They were asked to answer the following questions: „Which steps and projects regarding „ecological, economic and social sustainability“ do you implement as an actor at the university (faculty, research association, admistrative unit or university interest group)? Which definition, concept or model do you take as a basis for these activities?“ The contributions to this call are collected in this publication.:Vorwort.........................................................................................1 Forschungsbereich Biopolymere und Naturfaserverbunde (BNF).................3 Professur Energie und Hochspannungstechnik........................................7 Professur für Innovationsforschung und Technologiemanagement.............11 Bundesexzellenzcluster MERGE..........................................................15 Professur Nachrichtentechnik der TU Chemnitz.....................................18 NATUC – Referat für Ökologie und Nachhaltigkeit...................................21 Professur Personal und Führung.........................................................24 Professur Privatrecht und Recht des geistigen Eigentums........................28 SAXEED Gründernetzwerk..................................................................32 Studentenwerk Chemnitz-Zwickau......................................................36 Universitätsbibliothek.......................................................................40
52

Phase Validation Of Neurotoxic Animal Models Of Parkinson

Telkes, Ilknur 01 December 2012 (has links) (PDF)
Parkinson&rsquo / s disease (PD) is characterized by the progressive loss of dopaminergic nigral neurons and striatal dopamine resulting in serious motor deficits but also some non-motor anomalies. Animal models of human neurodegenerative diseases are essential for better understanding their pathogenesis and developing efficient therapeutic tools. There are many different PD models, however, none of them is fully reproducing all the symptoms of the disease. In addition, different investigators use different behavioral measures which makes even more difficult to compare and evaluate the results. The aim of the present study was to compare motor and cognitive deficits in two most common models of PD: the Rotenone and 6-OHDA model, using a large battery of neurological tests and a probabilistic learning task. To the best of our knowledge, this is the first study to examine the effects of bilaterally induced Rotenone and 6-OHDA through behavioral test batteries assessing the cardinal motor symptoms and the cognitive abnormality of Parkinson&rsquo / s Disease in the same rat population. Also, the present study is unique on the basis of providing both longitudinal observations of behaviour in the same treatment group and the cross-sectional comparisons of the behavioural responses between different groups. In the current study, the neurotoxins were applied at relatively low doses of 3-4 &mu / g, bilaterally to the substantia nigra pars compacta (SNpc). Experiments were conducted on 50 young-adult male Sprague&ndash / Dawley rats randomly assigned to five experimental groups: Rotenone, 6-OHDA, vehicle (DMSO/Saline), and the intact control. The neurological tests included locomotor activity,catalepsy, rearing, stepping, and rotarod/accelerod tests. They were applied prior to, and on days 4-7-10-20-40-150 while the learning task was applied 49 days after drug infusion.During the first 2 postoperational months, both neurotoxins produced progressive deterioration in motor performance but showing no effect on cognitive functions. Five months after the surgery, regression of bradykinesia but persistence of sensorimotor deficits was noted. The tests&rsquo / results suggest different susceptibility of different motor functions to the degeneration of nigro-striatal (N-S) pathway. So, different tests were demonstrated to have different power in detecting similar motor deficits.
53

Effects Of Chronic Ethanol Consumption On Memory And Molecular Changes In The Hippocampus Of Young Adult Wistar Rats

Elibol, Birsen 01 September 2007 (has links) (PDF)
The aim of the present study was to examine retention of spatial reference memory after 6 (Experiment I) and 15days (Experiment II) of binge-like drinking and during alcohol withdrawal in young adult Wistar rats. Prior to alcohol treatment, rats received Morris Water Maze (MWM) training. Afterwards, rats were intragastrically administered ethanol at the dose increasing from 4.5g-to-12g/kg. Intubation control groups (n=7 and n=10, respectively) received infusions of a sucrose solution without ethanol. Subsequently, all subjects were given a single probe trial in the MWM to test memory retention. In both experiments, there were three alcohol groups: A0 group (n=7) tested 4h after the last alcohol administration for acute effects of ethanol / A24 group (n=7) tested 24h after alcohol cessation, when acute ethanol effects disappear but withdrawal symptoms does not develop yet / A72 group (n=7) tested 72h after the last ethanol infusion for withdrawal effects. Finally, potential molecular changes in hippocampus were examined using Fourier Transform Infra-Red (FT-IR) spectroscopy. The blood alcohol concentration was 605.67&plusmn / 36mg/dl. In Experiment I, due to the low overall level of performance in the memory retention task the behavioral effects of ethanol could not be evaluated and no significant between&ndash / group differences were observed in Experiment II. In Experiment I, no significant changes in the molecular make-up of the hippocampus were noted. Conversely, in Experiment II, significant changes in protein, lipid, and nucleic acid profiles related to ethanol intake and withdrawal were found. They are linked to both development of tolerance to ethanol and adverse withdrawal effects.
54

Linear And Nonlinear Analysis Of Human Postural Sway

Celik, Huseyin 01 September 2008 (has links) (PDF)
Human upright posture exhibits an everlasting oscillatory behavior of complex nature, called as human postural sway. Variations in the position of the Center-of-Pressure (CoP) were used to describe the human postural sway. In this study / CoP data, which has experimentally been collected from 28 different subjects (14 males and 14 females with their ages ranging from 6 to 84), who were divided into 4 groups according to their ages has been analyzed. The data collection from each of the subjects was performed in 5 successive trials, each of which has lasted for 180-seconds long. Linear analysis methods such as the variance/standard deviation, Fast Fouri&eacute / r Transformation, and Power Spectral Density estimates were applied to the detrended CoP signal of human postural sway. Also the Run test and Ensemble averages methods were used to search for stationarity and ergodicity of the CoP signal respectively. Furthermore, in order to reveal the nonlinear characteristics of the human postural sway, its dynamics were reconstructed in m-dimensional state space from the CoPx signals. Then, the correlation dimension (D2) estimates from the embedded dynamics were calculated. Additionally, the statistical and dynamical measures computed were checked against any significant changes, which may occur during aging. The results of the study suggested that human postural sway is a stationary process when 180-second long biped quiet stance data is considered. In addition, it exhibits variable dynamical structure complex in nature (112 deterministic chaos versus 28 stochastic time series of human postural sway) for five successive trials of 28 different subjects. Moreover, we found that groups were significantly different in the correlation dimension (D2) measure (p&amp / #8804 / 0.0003). Finally, the behavior of the experimental CoPx signals was checked against two types of linear processes by using surrogate data method. The shuffled CoPx signals (Surrogate I) suggested that temporal order of CoPx is important / however, phase-randomization (Surrogate II) did not change the behavioral characteristics of the CoPx signal.
55

Housing Along The Western Development Corridor In Ankara: Case Studies In Etimesgut &amp / Sincan

Dogan, Derya 01 September 2008 (has links) (PDF)
Urbanisation and suburban housing development are the foci subjects of this thesis. The process of urbanisation may differ from one country to another in terms of socio-economic and political structures, environmental characteristics and also local features. In this context, housing areas at the urban fringe of Ankara were found to have been developed highly compatible with urban land use theories / but different from the process experienced in developed countries. In this thesis, a different dimension of suburbanisation has been discussed with regards to middle and lower-middle income groups&rsquo / suburban movement. The reasons why lower-middle and lower income residents prefer to live at the urban fringe have been found out. Suburban developments have various opportunities for the households such as larger housing unit due to cheap and available land, better urban services, quiet and clean environment and privacy. However, households living in urban fringe who are relatively from middle and lower-middle income are subject to high transportation cost. It is expected that they make a trade off between lower housing units and greater commuting distances and also many opportunities of living in such a suburb. With regard to these, the process of suburbanisation of middle and lower-middle income groups in Ankara within the boundaries of Sincan and Etimesgut Quarters in terms of their social characters and the features of using their urban space and house is discussed according to plan decisions, house builder and households&rsquo / characteristics, urban development pattern of Turkey and Ankara and then Etimesgut and Sincan, considering the theoretical basis and historical process.
56

Pharmakokinetik von Doxorubicin: Populationsvariabilität und Einfluss von genetischen Polymorphismen in Membran-Trasportproteinen / Pharmacokinetics Of Doxorubicin: Interindividual Variability And Impact Of Genetic Polymorphisms In Transmembrane Carrier-Systems

Wasser, Katrin 09 June 2008 (has links)
No description available.
57

Success nonetheless : making public utilities work in small-scale democracies despite social capital difficulties

Douglas, Scott C. January 2011 (has links)
A large part of the study of politics is dedicated to identifying the circumstances under which democracy will flourish. Putnam made a major contribution to this field through his concept of social capital as developed in Making Democracy Work. Putnam found that communities with a high number of civic associations –i.e. social capital- had a better chance of developing an effective style of democratic government. This definition of social capital sparked much subsequent research and policy activity. It is argued here, however, that this work ignored the immediate needs of societies which do not have the required stock of social capital. There is still little guidance available on how effective government can be achieved even if the right societal circumstances are absent. This thesis hopes to find inspiration from government agencies that were successful despite their challenging social capital conditions. It specifically looks at sixteen public utilities on the Caribbean islands of Aruba, Curacao and St. Kitts between 2005 and 2009. The thesis then systematically investigates the relationship between the performance of the agencies and the behaviour of their senior officials. It emerges that in the absence of social capital, governance is in these cases mainly hampered by a deluge of irrelevant data. Successful utilities overcame this flood by constantly upgrading the quality of information, implementing a strict yet inclusive style of governance, and allowing strong leaders the space to translate words into actions. These outcomes suggest that social capital forms an important tool for ordering information, and that, in its absence, there are still alternative strategies available to secure success nonetheless.
58

Senate Bill 351's Effect on School Finance Equity in Texas

Henry, John Mark 12 1900 (has links)
The purpose of this study was to determine the impact of Senate Bill 351 on public school finance equity in Texas and to provide information to those concerned with the financing of schools in this state. Data provided by the Texas Education Agency were used to determine differences in expenditures per student and local tax rates before and after the implementation of Senate Bill 351.
59

La dynamique de la complexité en matière de relations extérieures des Etats membres de l'Union européenne / The complexity dynamics of the European Union's member states' external relations

Ličková, Magdalena 16 April 2013 (has links)
Lorsqu’il devient membre de l’Union, l’État accepte de se soumettre à un ensemble de règles venant limiter son autonomie extérieure. Si cet ensemble peut être analysé en termes d’effets juridiques-types agissant d’une manière unilatérale sur cet État membre, notre travail a tenté d’examiner ce que nous croyons être une chaîne dynamique d’actions, de réactions et de rétroactions qui est, à ce titre, complexe. En effet, au cours de nos travaux, nous nous sommes rendus compte que loin d’être unilatérale, la manière dont le droit de l’Union marque les compétences externes des États membres prend en réalité la forme d’interactions permanentes entre l’État membre intégré et l’Union, entre l’Union et l’État membre global, ou encore entre l’État membre intégré et l’État global. Si l’État intégré s’efface pour laisser l’Union agir à sa place ou s’il agit conjointement avec elle, cet effacement ne concerne pas son aspect global, son alter ego, qui revient ou simplement reste sur la scène afin de compléter et concurrencer l’action de l’Union, ou encore pour rechercher l’appui de cette dernière dans sa relation avec les tiers. L’État membre qui apparaissait initialement passif, s’érige alors en contributeur actif de ce dynamisme tissé dans les rapports juridiques entre l’ensemble européen et les tiers, par la rétroaction de ses compétences souveraines ou par l’exercice concurrent de ces dernières. Ceci montre qu’une étude des relations extérieures de l’Union ne peut pas être complète sans une étude simultanée des effets que le droit de l’Union produits sur les États membres intégrés et que ce dernier subit à son tour par les États membres globaux. Elle ne peut pas être non plus être complète sans un examen des effets que le droit international produit sur les États membres globaux et que ce dernier subit, à son tour, du fait des États membres intégrés. / In its capacity of a member of the European Union, the State agrees to submit to a set of rules framing its autonomy in the field of external relations. While this set of rules can be assessed in terms of categories of legal effects acting unilaterally upon the EU Member State, the present study attempts to go further by examining what we believe to be a dynamic chain of complexity, composed of actions, reactions, and retroactions of the actors involved. During our research, we indeed found that the manner in which the Union affects the EU Member States’ external relations is far from being a one-way process, but rather constitutes permanent and circular dynamics of interaction between what we shall call an integrated Member State and the Union, between the Union and what we shall call a global Member State, and between the respective Member State’s global and integrated faces. The integrated Member State may step aside to let the Union act in its stead, or act in conjunction with the Union, but ʽtaking the back seatʼ in this manner does not engage its global face, its alter ego, which will return to take center stage (if it did not simply stay there to begin with) to complete (or to compete with) the actions of the Union, or even to solicit the Unionʼs support with respect to the relations it established vis-à-vis third parties. As we proceed, we find that the Member State, who initially appeared to be a mere passive object of our research, is in fact an active agent, contributing, whether through retroaction or through the competing exercise of its sovereign competencies, to the face of the Unionʼs external relations. Accordingly, no research into the external relations of the EU can be complete without taking into account the impact of EU law on the integrated Member States, and the impact felt in turn by the EU as the result of the Member Statesʼ global actions. In the same way, such research should consider the impact of international law on the global Member States and the impact felt in turn by international law as a result of the actions of the integrated face of these same Member States.
60

Assessment Of Sub-center Development: Batikent, Ankara

Celep, Serhat 01 November 2009 (has links) (PDF)
Sub-center formation is closely come out when urban environment started to grow and by decentralization and sub-urbanization process to lower the congestions and increase the efficiency in urban life. Besides, by means of rising problems of the growth in an urban area, there emerged the need to share the central activities within the metropolitan region. The growth followed by creation of new towns in the peripheries. Within that organization of the city, sub-centers started to appear to share the burden of the city centers. In this study, the sub-center evolution will be examined with respect to its relationship to urban growth and development. Hence the sub-center formation will be defined and studied in terms of city center, neighborhood center and shopping center developments of the settlements. The criteria on land-use, planning process, design of the built environment, district and neighborhood centers and policies of revisions in the suburb within world examples will help the study to develop principles for sub-center formation. This will provide us to build up some criteria for the central area especially in New Development areas. After the 1970s, the city of Ankara expanded rapidly and there emerged new development areas of the metropolitan region in the West Corridor. With respect to these, Ankara is analyzed with a new urban development area in that corridor called Batikent. With the help of discussions and analysis on sub-center formation on smaller plots belonging to private and a world example of sub-center development produced by the government, design and planning principles of Sub-center growth and development will be proposed in case of Batikent.

Page generated in 0.0552 seconds