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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Le père et le genre : la paternité en question par l’aide médicale à la procréation pour des hommes transgenres / Father and gender : questionning fatherhood in medical assistance for procreation to transgender men

Mendes, Nicolas 23 November 2018 (has links)
Ce travail de recherche propose une première approche pour penser la paternité d’hommes transgenres ayant eu recours à un don de spermatozoïdes par l’aide médicale à la procréation (AMP). Vingt années après l’engagement du premier Centre de conservation des œufs et du sperme (CECOS) d’accompagner ces demandes de couples, et la publication de la seule étude sur la qualité du développement de ces enfants, une réflexion sur la paternité de ces hommes nés femmes et aujourd’hui pères se révèle nécessaire. Pour cheminer autour de ces réflexions, une revisite des considérations psychanalytiques freudiennes et lacaniennes de l’identité, mais également du genre grâce aux apports des Gender Studies et de la paternité articulée aux structures anthropologiques de la parenté, nous a permis de discuter des possibles reconsidérations théoriques actuelles. La pratique du don de gamètes est aussi abordée en lien avec les questionnements cliniques autour de la transmission, et des réflexions bioéthiques qui émergent. Depuis un paradigme analytique, admettant une alliance avec les méthodes phénoménologiques, un outil initialement quantitatif, le Five Minute Speach Sample (FMSS) fut adapté dans sa méthode d’analyse pour répondre à la question : Comment un sujet homme né femme, définit-il sa paternité à la suite d’un contexte d’accès à la parentalité par le recours à une insémination artificielle avec tiers donneur anonyme de spermatozoïdes (IAD) ? Le recueil des discours en libre association de seize pères transgenres et son analyse de contenu thématique ont permis de constituer une représentation de l’expérience de paternité de ces hommes transgenres.L’émergence de points de tension au sein de ses discours nous a amenés à repérer trois ensembles de signes d’intranquilité qui peuvent, pour certains être rencontrés spécifiquement sur ce cheminement de la paternité. Le repérage de ces points d’intranquilité est discuté dans l’intérêt de l’accueil des demandes et de l’accompagnement de la transidentité. / This study allows a first reflection on the fatherhood of transgender men who have used sperm donation with medically assisted procreation. Twenty years ago, the first French sperm bank offered to accompany the request of heterosexual couples which transgender men. To this day only one study about these couples has been published but focused on the development of their children. A reflection on the fatherhood of these men born as women and who are now fathers appears to be necessary. To study this new situation, we have reviewed the psychoanalytic concepts of identity brought to us by Freud and Lacan, and the concept of gender brought to us by the Gender Studies. Also, fatherhood is discussed with the anthropological approach on structure of kinship. The gamete’s donation is addressed in relation to the clinical concept of transmission and the bioethical questioning that it rises. From a psychoanalytical paradigm, we admit a relationship with the phenomenological approach. A quantitative tool (the Five Minute Speech Sample) was adapted in its analysis method to answer: how does a person born as a women and now living as a man will define his fatherhood when benefitting of anonymous sperm insemination in medically assisted procreation? We analyzed the free speech of sixteen transgender men to build a representation of fatherhood in these specific experiences. Points of tension have allowed to identify three sets of disquiets’ signs. Some of them can be encountered in the process toward this specific kind of fatherhood. Being aware of these disquiets’ signs could help us accompany more appropriately people in the quest of their transgender lives.
12

Políticas públicas em saúde mental no Brasil na perspectiva do biodireito: a experiência dos estados de Minas Gerais e São Paulo sob a égide da lei 10.216/2001 e suas implicações

Musse, Luciana Barbosa 18 September 2006 (has links)
Made available in DSpace on 2016-04-26T20:24:34Z (GMT). No. of bitstreams: 1 TESE LUCIANA BARBOSA MUSSE.pdf: 1420442 bytes, checksum: 53ed326b77b421b43cc84bbec5bc013d (MD5) Previous issue date: 2006-09-18 / This research was conducted with the purpose of elucidating the public policies concerning mental health care in Brazil adopted since the promulgation of the law n. 10.216/2001 and which contemplate the mental disturbance carrier attendance and his rights. In order to analyze them, as well as its implications, Biolaw was adopted as reference, considered as a dogmatic theoretical construction, aiming the standard interpretation for juridical decision taking, in order to identify the rationality criterion that surrounds them if efficiency or public ethics. Considering that, since the 1988 Federal Constitution, the whole actions and services supply concerning mental health care are conducted by state, municipal or federal institutions or by the private initiative, with complementary character, the SUS , that is organized based on the regionalism, decentralization and hierarchy principles, the experience of two federal state members was elected, specifically the states of Minas Gerais and Sao Paulo, in order to illustrate the implementation process of strategies adopted by Brazilian public policies concerning mental health care, under the aegis of the law n. 10.216/2001. The data were collected through observation and with the application of questionnaires, answered by (mental) health professionals and by users (or their legal responsible) of hospital and health care services or by mental health care of the states of Minas Gerais and Sao Paulo. Besides those two documentation techniques, this research is based on the historical method, together with the statistic and comparative methods which permits the conclusion that prevailing rationality among public policies concerning mental health care adopted by the Brazilian state is the ethics, that, meanwhile, to be effective, depends on the efficiency and creates implications for the user and mental disturbance carrier that extrapolates the standard limits of the law n. 10.216/2001 and trespasses others meanderings of its existence, especially its juridical and ethical autonomy which creates reflexes, in turn, in the fruition of its recently conquered citizenship / Esta pesquisa tem como objeto as políticas públicas em saúde mental no Brasil, adotadas a partir da promulgação da lei n. 10.216/2001 e que contemplam a assistência ao portador de transtorno mental e seus direitos. Para analisá-las, bem como as suas implicações, adota-se como referencial o Biodireito, entendido como uma construção teórico-dogmática com vistas à interpretação normativa para a tomada de decisão judicial, a fim de identificar o critério de racionalidade que as permeia - se a eficiência ou a ética pública. Tendo-se em vista que, desde a CF/88 o conjunto das ações e da oferta de serviços em saúde mental, dá-se por meio de órgãos e instituições federais, estaduais e municipais, bem como da iniciativa privada, em caráter complementar, o SUS, que se organiza de acordo com os princípios da regionalização, descentralização e hierarquização, elegeu-se a experiência de dois estadosmembros da federação, notadamente, Minas Gerais e São Paulo, para ilustrar o processo de implantação das estratégias adotadas pelas políticas públicas brasileiras em saúde mental, sob a égide da lei n. 10.216/2001. Os dados foram coletados por meio de observação e aplicação de questionários, respondidos por profissionais da saúde (mental) e por usuários (ou seu responsável legal) de serviços hospitalares e comunitários de saúde ou saúde mental de Minas Gerais e São Paulo. Além dessas duas técnicas de documentação, a pesquisa é pautada pelo método histórico, aliado ao estatístico e ao comparativo, que permitem concluir que a racionalidade predominante nas políticas públicas em saúde mental, adotadas pelo Estado Brasileiro é a ética, que, entretanto, para ter efetividade, depende da eficiência e gera implicações para o usuário portador de transtorno mental que extrapolam os limites normativos da lei n. 10.216/2001 e invadem outros meandros da sua existência, em especial a sua autonomia ético-jurídica, que reflete, por sua vez, no gozo da sua cidadania recém conquistada
13

Avaliação do ensino de ética médica nas escolas médicas de Salvador-Bahia-Brasil: elementos contributivos para a humanização da medicina

Neves, Nedy Maria Branco Cerqueira January 2005 (has links)
Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-05-06T13:31:16Z No. of bitstreams: 1 Neves, Nedy.pdf: 1850519 bytes, checksum: 807985f7e76df63c189543a8a9283e68 (MD5) / Approved for entry into archive by Maria Auxiliadora Lopes(silopes@ufba.br) on 2013-05-16T17:51:00Z (GMT) No. of bitstreams: 1 Neves, Nedy.pdf: 1850519 bytes, checksum: 807985f7e76df63c189543a8a9283e68 (MD5) / Made available in DSpace on 2013-05-16T17:51:00Z (GMT). No. of bitstreams: 1 Neves, Nedy.pdf: 1850519 bytes, checksum: 807985f7e76df63c189543a8a9283e68 (MD5) Previous issue date: 2005 / Este trabalho pretende fazer uma avaliação no ensino de Ética Médica nas escolas médicas de Salvador-Bahia, propondo elementos contributivos para a humanização da Medicina, através da análise das alterações introduzidas no currículo e na abordagem metodológica. A justificativa do tema é conseqüente à demanda da sociedade contemporânea que clama pela ³KXPDQL]DomR¥ dos médicos e da medicina. A evolução técnico-científica gerou uma gama de exames e procedimentos, dando um novo direcionamento à medicina científica ocidental contemporânea, afastando o médico da arte de curar. Este modelo não deve evoluir para o distanciamento da relação médico-paciente e sim para ser um auxílio diagnóstico e terapêutico. A pesquisa bibliográfica foi realizada através da utilização de livros-texto e de artigos publicados em revistas indexadas, que gerou o referencial teórico. Este material foi dividido em cinco capítulos. No primeiro capítulo foi abordada a conceituação de termos utilizados na área, como: ética, moral, deontologia, diceologia e ética médica. O segundo, foi dedicado à Bioética, com a contextualização, o histórico, os princípios e tendências. O terceiro abordou os códigos de ética e os códigos de ética médica. O quarto foi dedicado ao ensino, o ensino brasileiro a época da criação das escolas médicas e o ensino médico, com as principais reformas curriculares. O quinto capítulo, foi dedicado ao ensino de Ética Médica, através de questionamento de como, por que, quando, quem deve ensinar e como avaliar. Foi ainda realizada uma pesquisa documental e um levantamento através de análise quantitativa, utilizando questionários para os discentes e uma avaliação qualitativa, através de entrevistas para os docentes. O trabalho foi concluído com a percepção que muito ainda precisa ser transformado para que o ensino seja eficaz na transmissão de valores. / Salvador
14

ZEUS VERSUS PROMETEU: O embate discursivo nos artigos opinativos favoráveis e contrários à pesquisa com células-tronco embrionárias

Oliveira, José Aparecido de 24 March 2008 (has links)
Made available in DSpace on 2016-08-03T12:30:42Z (GMT). No. of bitstreams: 1 Dissertacao.pdf: 995537 bytes, checksum: 8b045ac17f646e609f8778ffdc19704d (MD5) Previous issue date: 2008-03-24 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / From the perspective of French Discourse Analysis, this work examines specialized discourses (scientific, religious, judicial, journalistic, political) found in mass media featured articles about the scope of the Biosafety Law, mainly about ADI # 3510 judged by the Republic ex-solicitor general Claudio Fontelles. Its data are opinion featured articles issued in the papers Folha de S. Paulo and O Estado de S. Paulo, in the first semester of 2005, as well as the quoted source-documents from the Catholic Magisterium (Evangelium Vitae; Document about the Production and Scientific and Therapeutic Utilization of Human Embryonic Stem Cells; and the Donum Vitae Instruction). It s intended to verify the language modus operandi in these discourses, especially the ideological features found in their construction as persuasive elements. The research results allow the conclusion that there are dogmatic elements in these discourses, aligned with the ideology of the groups to which the writers belong, as well as mythical-philosophical-religious elements, according to the notion of Founder Discourse (Discurso Fundador) by Eni Orlandi.(AU) / A partir da perspectiva da Análise de Discurso de linha francesa, este trabalho analisa os discursos especializados (científico, religioso, jurídico, jornalístico, político) presentes em artigos na mídia massiva sobre a cobertura da Lei de Biossegurança, sobretudo a partir do ajuizamento da ADI Nº 3510, pelo ex-procurador geral da República, Claudio Fontelles. Os dados são artigos opinativos publicados nos jornais Folha de S. Paulo e O Estado de S. Paulo, no primeiro semestre de 2005, bem como os documentos-fonte do Magistério Católico citados (Evangelium Vitae; Declaração sobre a Produção e o Uso Científico e Terapêutico das Células Estaminais Embrionárias Humanas; e a Instrução Donum Vitae,). Pretende-se verificar o modus operandi da linguagem nestes discursos, sobretudo os aspectos ideológicos de sua construção como elementos persuasivos. Os resultados da pesquisa permitem concluir a presença de elementos dogmáticos nestes discursos, alinhados com o posicionamento ideológico dos grupos aos quais pertencem os articulistas, bem como a presença de elementos mítico-filosófico-religiosos, conforme a noção de Discurso Fundador, de Eni Orlandi.(AU)
15

Stratégie du numérique (intelligence stratégique) de l'Église Catholique de France pour confronter sa position sur les questions de société : le rôle de la blogosphère catholique dans le débat sur la révision de la loi de bioéthique / Strategy of the digital technology (strategic intelligence) of the French Catholic Church to defend its position on society issues : the role of the catholic blogosphere of the debate on revision of the bioethics law.

Koffi, Joël 30 March 2015 (has links)
La prépondérance des outils numériques dans l’espace communicationnel revèle l’enjeu de leurs utilisations éfficientes pour les acteurs de la société dans leurs stratégies d’expression et d’influence. Ce travail propose une exploration au coeur de l’univers d’un de ces outils (le blog) pour une compréhension de son fonctionnement en vue de dégager les potentialités stratégiques de son utilisation par un acteur particulier de la société: l’Église catholique de France. La première partie de cette recherche a consisté à expliciter les différents concepts qui ont été mobilisés : l’intelligence stratégique, le blog, et la notion de participation à des débats de société. Cette étape de définition s’est avérée nécessaire car, elle nous a permis, par notre définition de l’intelligence stratégique, de choisir l’angle suivant lequel, nous avons conduit la présentation du concept du blogs. La seconde partie de notre travail présente progressivement l’émergence de l’intelligence stratégique dans le cadre de la révision de la loi de bioéthique de l’Église catholique. Dans cette présentation, nous avons explicité les particularités (la diversité, la fugacité et la complexité) d’un terrain d’étude comme la blogosphère catholique. Ces particularités nous ont amené à l’adoption d’une méthode de sélection de blogs faisant référence à Google, et à une technique d’archivage dynamique des blogs. Par la suite nous avons essayé d’appréhender cette blogosphère catholique, par une explicitation de l’organisation et du fonctionnement institutionnel de l’Église catholique. / The Ascendancy of digital tools in the domain of communication reveals the importance of their efficient use for social actors in their strategies of expression and influence. This study proposes an exploration into the heart of the universe of one of these tools (the blog) to understand it’s function in order to identify potential strategic use by a specific actor in society: the Catholic Church in France. The first part of this research consisted in clarifying the various concepts used: strategic intelligence, the blog, and the notion of participating in social debates. This definition phase proved to be necessary, because it allowed us, by using our definition of strategic intelligence, to choose the approach from which the concept of blogs would be presented. The second part of our study gradually shows the emergence of strategic intelligence regarding the revision of bioethical laws in the Catholic Church. In this study, we explain the specificities (diversity, fugacity and complexity) for a field of study such as the Catholic blogosphere. These features have led us to adopt a method of selecting blogs referenced by Google, and to a technique of dynamic archiving of blogs. Subsequently we have tried to approach this Catholic blogosphere, by clarifying the organization and institutional functioning of the Catholic Church.
16

Les pratiques culturelles des excisions et des infibulations à Bamako au Mali : la contribution de la dignité humaine au respect de l’intégrité physique des femmes

Dembélé, Moïse 08 1900 (has links)
Une des questions les plus débattues dans le domaine de l’éthique en ce XXIème siècle entre l’Afrique et le monde occidental concerne le respect de l’intégrité physique des femmes. Parmi les actions humaines qui touchent le plus l’intégrité corporelle, les excisions et les infibulations sont les plus dénoncées en Afrique. Longtemps considérées comme des rites d’initiation pubertaire des filles, ces pratiques sont maintenant considérées comme néfastes à la santé, et communément désignées par la communauté internationale de « mutilations sexuelles féminines ». Au cours des dernières décennies, ces pratiques ont été progressivement interdites légalement tant dans la plupart des pays d’Afrique que dans les pays occidentaux. Le Comité Inter-Africain (CIAF) contre les mutilations sexuelles demande la « tolérance zéro » par rapport à ces pratiques. La communauté internationale les combat avec des armes juridiques, en se référant aux conséquences médicales et aux droits de l’homme. Notre thèse est née d’une interrogation sur les raisons pour lesquelles ces rites se poursuivent encore en Afrique et plus spécialement au Mali, alors que dans les pays occidentaux, on élève fortement la voix pour les dénoncer comme sévices infligés aux femmes. Sur le plan international, on hésite à imposer des valeurs universelles à un phénomène perçu dans une large mesure comme une tradition conforme aux normes sociales des communautés qui les maintiennent. Afin de mieux cerner le sujet, notre questionnement a été le suivant : « Comment les pratiques culturelles des excisions et des infibulations, dans la ville de Bamako au Mali, interpellent-elles l’éthique : en quoi l’analyse de ces rites constitue-t-elle un domaine légitime d’application des principes de la bioéthique ? » Notre réflexion part du postulat que la dignité humaine est une norme à l’aune de laquelle se mesurent les défis éthiques liés à ces rites. Un proverbe Bambara dit ceci : « Une seule main ne lave pas proprement un éléphant ». La logique de cette sagesse met en évidence qu’une seule approche disciplinaire ne saurait faire ressortir les enjeux éthiques de ces pratiques. Notre analyse bioéthique se veut une démarche interdisciplinaire, qui permet d’articuler les approches philosophiques, anthropologiques, sociologiques et biomédicales de ces pratiques. Le premier chapitre, à travers la revue des écrits, présente la problématique de ces rites. Le deuxième chapitre présente le cadre théorique basé sur la notion de dignité humaine et délimite « ses contours, ses sources, ses formes et ses conséquences » afin de la rendre plus efficace et opérationnelle comme moyen de protection de l’être humain. Le troisième chapitre présente la méthodologie de la recherche basée sur la méthode qualitative et l’induction analytique et décrit le contexte de l’étude. Le quatrième chapitre présente les résultats de la recherche qui font ressortir que ces pratiques se résument essentiellement au contrôle du désir sexuel féminin. Ces pratiques sont par ailleurs déritualisées, touchent de plus en plus des enfants, comportent des risques et des conséquences sur la santé avec des coûts humains et financiers pour la société. Le cinquième chapitre analyse ces pratiques avec les principes éthiques qui démontrent qu’elles constituent un problème de santé publique malgré leur caractère culturel. Enfin, le sixième chapitre présente la portée et la limite de la thèse. Celle-ci montre qu’il est possible de mener un débat sur les excisions et les infibulations à travers une éthique de discussion. Elle offre un moyen pour y parvenir avec une vision de la notion de dignité humaine comme une « valeur éthique universelle » susceptible d’être utilisée dans toutes les actions impliquant l’être humain et dans tous les contextes socio-culturels. Notre démarche élargit ainsi le champ d’application des principes bioéthiques à des pratiques non-médicales. Par cette thèse, nous souhaitons contribuer à enrichir la réflexion éthique sur les excisions et les infibulations et inspirer les politiques de santé publique dans le respect des diversités culturelles. Nous espérons pouvoir inspirer aussi d’autres recherches en vue de rapprocher la bioéthique des pratiques culturelles traditionnelles afin de trouver des compromis raisonnables qui pourraient renforcer le rôle de protection de la dignité humaine. / One of the most debated issues in the area of ethics in the twenty first century between Africa and the Western world concerns the respect for the women’s physical integrity. Among human actions that most affect the bodily integrity of women, female circumcision and infibulation are the most denounced in Africa. Long regarded as rites of puberty and initiation of girls, these practices are now considered as exceedingly harmful to health, and commonly called "female genital mutilation" (FGM) by the international community. In recent decades, these practices have gradually been legally prohibited in most African countries as well as in Western countries. The Inter-African Committee on Traditional Practices Affecting the Health of Women and Children (IAC) demands 'zero tolerance'. The international community fights them with legal weapons, basing on the medical consequences and the infringement of human rights. Our thesis was born from a question on the reasons why these rites are still going on in Africa and more especially in Mali, while in Western countries; voices are strongly raised to denounce them as abusive to women. On the international front, we hesitate to impose universal values to a phenomenon, perceived to a large extent as a tradition in conformity with the social norms of the communities that maintain them. In order to better circumscribe the subject, our question is as follows: “How do the cultural practices of female circumcision and infibulation in the city of Bamako, Mali, challenge ethical norms : in what way does the analysis of these rites constitute a legitimate sphere of application of the principles of bioethics?” Our reflection starts from the assumption that human dignity is a standard against which measuring the ethical challenges associated with these rites. A Bambara proverb says: “One hand does not properly wash an elephant.” The logic of this wisdom highlights the fact that using only one approach from a certain discipline cannot bring out the ethical issues of these practices. Our bioethical analysis is meant to be an interdisciplinary approach that allows one to articulate the philosophical, anthropological, sociological and biomedical approaches to these practices. The first chapter, through the literature review, presents the problem associated with these rites. The second chapter presents the theoretical framework based on the concept of human dignity, and delineates its contours: its sources, its forms and its consequences in order to make it more effective and operational as means of protection of the human being. The chapter three presents the methodology of the research based on the qualitative method and analytical induction, and describes the context of the study. The chapter four presents the results of the research which highlights the fact that these practices essentially refer to the control of female sexual desire. These practices are also “deritualized” and affect more and more children, which involves risks and consequences on health with enormous human and financial costs to society. The fifth chapter analyses these practices with the ethical principles which demonstrate that these ritual practices constitute a public health problem despite their cultural character finally. The sixth chapter presents the scope and the limit of the thesis. It shows that it is possible to have a debate on female circumcision and infibulation through an ethic of discussion. It provides a way to achieve this with a vision of the concept of human dignity as a “universal ethical value” which can be used in all actions involving the human being and in all socio-cultural contexts. Our approach broadens the field of application of the bioethical principles to non-medical practices. By this thesis, we wish to contribute to the enrichment of the ethical reflection on female circumcision and infibulation and to inspire public health policies keeping in mind the respect for cultural diversity. We also hope to inspire further research in view of bringing together the bioethics of traditional cultural practices in order to find reasonable compromises which could strengthen the role of protection of human dignity.
17

生技醫藥公司之投資評估研究-生物倫理與社會責任之價值

陳宜超, Chen,Yi-Chau Unknown Date (has links)
繼人體基因圖譜於2000年解碼後,基因解讀及研究初期均在競爭解讀基因序列(Gene sequences),然而了解基因序列是一件事,如何從序列中來了解基因功能所賦予之生理生化意義,比如每段基因所產生之蛋白質產物、及蛋白質與細胞之間的相互關係等資訊,進而應用於藥物標的之尋找,才是未來生物醫學發展之主要方向。同理,藉由基因功能學(Functional Genomics)領域來研究新發現之基因的功能、基因表現、與蛋白質產物,進而辨識有用的藥物標的(Drug target)及尋找新的疾病治療方法,才是基因解讀後最主要之生技醫療市場。全球生物科技之應用中以醫療用的生技產品所帶來的產值最為可觀,佔總體生技產業約七成以上之產值,其中又以重組蛋白藥品、單株抗體、疫苗及檢驗試劑之研發為主要重心,其中行政院更在“加強生物技術產業推動方案”裡,特別將蛋白藥物、抗癌藥物開發及檢驗試劑等領域列為重點推動項目,國內外許多生物科技公司研發專長及主軸亦座落於全球最熱門的生技製藥發展脈絡上。目前由於許多癌症、代謝失常疾病、遺傳性疾病及自體免疫疾病等,臨床之治療藥物仍舊是付之闕如或是供不應求,其中特別是各種癌症以及自體免疫疾病,如類風濕性關節炎、多發性硬化症、牛皮癬及過敏等,都是生技醫藥開發非常重要之疾病研究領域。現今臨床上所常用的藥物,普遍有特異性不佳、副作用大的缺點,因此國內外許多生物科技公司正戮力於針對上述疾病類別找尋合適之生技藥物或是小分子藥物,已達到標的治療(Target therapy)為目的;然而在生技醫藥公司草創初期,大都以技術掛帥,且由於藥品開發時間冗長,因此鮮少有生技醫藥公司能於設立初期10年內有產品上市,因此導致初期營運風險居高不下,令投資者裹足不前,所以如何評估具有成長潛力之生技醫藥公司頗為困難,因此本論文擬從生技藥品著手,除了傳統從技術面、產品面、市場面、競爭者、人力資源、策略經營等構面著手分析成長中之生技醫藥公司外,由於生技醫藥產業之特殊屬性,所以更特別注重產業成長時針對生物倫理面的考量,以做為生技醫藥公司具成長潛力之指標之一。希望透過多元的評估分析,能夠歸納出生技醫藥公司的成功要素,並藉此分析能夠有系統的篩選出具成長性、具社會責任之生技醫藥公司,才能擘畫生技醫藥公司維持長期競爭力、獲得永續發展的遠景,並藉此做為投資者長期投資評估之參考依據。 / The completion of the human genome project is regarded as a turning point in biotechnology and medicine. This project is expected to produce sequence of DNA representing the functional blueprint and evolutionary history of the human species. As we entered the postgenomic era, what we faced is the explosion of new information, which is leading to dramatic changes in the way we are able to study and manipulation of life. At the first few years, many groups were competing in sequence decoding. However, the findings of the functions of genes and the interactions of different gene products are the main issues helping us exploit the new biotechnology markets. Through the research of functional genomics to explore the function, expression, and protein products of novel genes is helpful in identifying new drug targets and developing therapeutic strategies in treating various diseases. This is what we emphasized in biotech market after entering the postgenomic era. The most valuable branch of biotechnology industry is the medical products in global biotechnology market. The medical products take up to 70% of total sales in biotechnology markets. Among the medical biotechnology field, recombinant protein drugs, monoclonal antibodies, vaccines, and detection kits have been focused in pharmaceutical R&D investment. Executive yuan of the Republic of China decided to emphasized in protein drugs, anti-cancer drug development and detection kits in their “ The promotion plan of improving biotechnology industry”. Currently, the drugs against cancers, metabolic diseases, inherited diseases, and autoimmune diseases are still unavailable. Especially the drugs for various cancers, and autoimmune diseases including rheumatoid arthritis, multiple sclerosis, psoriasis, and allergy are under intensive investment in global biotechnology industry. This is because the drugs used today have the deficiencies including low specificity and adverse side effects. Thus, target therapy using monoclonal antibodies and small molecular drugs are the goals for worldwide biotech companies. However, the development in research has been considered as the most important thing in the starting stage of newly founded biotech companies and the long time needed for putting a new drug to market make very few biotech companies have salable products. Thus, the newly biotechnology company has been considered has high risk in the beginning stage. This makes investors to hesitate in putting their money in this field. To evaluate the potential of a new biotechnology companies is difficult since the complex of this industry. This study will try evaluating a newly founded biotechnology company not only through technology, product, market, competitors, human resources, strategies, but also from the consideration in bioethics. Hopefully, through the evaluation of multiple markers, we can conclude the essential factors for a successful company and screen out the company with high growing potential via this study. Finally, this study might serve as a reference for investors in evaluating a promising company for long-term investment.

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