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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Part I : synthesis of azetidin-2-ones from pyrazolidin-3-ones ; Part II : synthesis of a subunit of the immunosuppressant FK-506

Toske, Steven Gerald 10 June 1993 (has links)
Graduation date: 1994
12

Hon borde kunna prata och läsa som andra mammor : En kvalitativ text- och innehållsanalys av etnicitet i bilderböcker

Willstedt, Anna January 2014 (has links)
Syftet med denna studie är att granska hur den bild som förmedlas av individer med en annan etnisk bakgrund än svensk är konstruerad i bilderböcker. Detta sker genom en kvalitativ text- och innehållsanalys av fem bilderböcker utgivna mellan år 1995 - 2012. Böckerna som analyseras är Noah och bästa grejen, En hög med snö, Den andra mamman, Alfons och soldatpappan samt Afrika bakom staketet. För att uppnå syftet har tre frågeställningar formulerats: hur sker personskildringen av individer med en annan etnicitet än svensk? Hur används miljön i skildringen av individer med en annan etnicitet än svensk? Hur samverkar text och bild i skildringen av personer med en annan etnicitet än svensk? Resultatet som framkommit visar att författare väljer att närma sig etnicitet på olika sätt. En del framhäver explicit individers etniska ursprung, och andra väljer att inte kommentera en persons etniska bakgrund. I alla böcker, förutom i en, skildras individerna med ett annat etniskt ursprung med mörk hy och mörkt hår. I alla böcker skildras västerländska klädesplagg. Endast en sekvens i en bok skildrar icke västerländska kläder. Färgerna på klädesplaggen har uppmärksammats som en skillnad mellan individer med en svensk etnicitet och individer med en annan etnicitet än svensk. Personbeskrivningen sker i fyra av fem böcker endast genom bild. I två av böckerna har det uppmärksammats hur miljön bidrar till personbeskrivningen av individer med en annan etnisk bakgrund än svensk. Vid granskning av miljön har flera olika föremål framträtt som talar om för läsaren att en person har en annan etnisk bakgrund än svensk.
13

Economically beneficial drug interactions with cyclosporin and tacroliumus : clinical studies in recipients of kidney and liver transplants /

Jones, Terence Edward. January 2000 (has links) (PDF)
Thesis (Ph.D.) -- University of Adelaide, Dept. of Clinical and Experimental Pharmacology, 2001. / Bibliography: leaves 234-257.
14

The role of cyclosporin A, leptin, and FK-506 in Leishmania major infections in mice

Potter, Shannon M. January 2009 (has links)
Thesis (M.A.)--Ball State University, 2009. / Title from PDF t.p. (viewed on Mar. 25, 2010). Research paper (M.A.), 3 hrs. Includes bibliographical references (p. [49]-53).
15

Estudo do efeito antiinflamatório do tacrolimus no modelo de pleurisia, em camundongos

Pereira, Robson Roman January 2006 (has links)
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas. / Made available in DSpace on 2012-10-22T22:46:04Z (GMT). No. of bitstreams: 1 235242.pdf: 663338 bytes, checksum: eeaf08a18f8ac5465bab02755126cfc5 (MD5) / Introdução: O tacrolimus é um agente imunossupressor isolado do Streptomyces tsukubaensis e é utilizado principalmente na prevenção de rejeição de órgãos. Além disso, muitos trabalhos têm demonstrado o uso do tacrolimus em doenças de caráter inflamatório crônico como à asma brônquica e artrite reumatóide.
16

Estudo do tacrolimus sobre a resposta inflamatória induzida pela carragenina no modelo da bolsa de ar, em camundongos

Vigil, Silvana Virginia Gagliotti January 2008 (has links)
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia. / Made available in DSpace on 2012-10-23T23:45:16Z (GMT). No. of bitstreams: 1 251003.pdf: 562113 bytes, checksum: 2e6d39d6a93c258d38f3f5ad1667ebfc (MD5) / Introdução: Tacrolimus é um imunossupressor da classe dos macrolídeos utilizado na clínica para evitar a regeição em transplantes de órgãos e no tratamento da dermatite atópica. Objetivo: O objetivo do presente estudo foi elucidar a atividade antiinflamatória do tacrolimus na inflamação induzida pela carragenina, no modelo da bolsa de ar, em camundongos. Metodologia: Camundongos albinos Swiss receberam injeção de 1,5 ml de ar no dorso, durante três dias alternados, para formação da bolsa de ar. No sexto dia, os animais receberam carragenina (Cg, 1%, s.c.) e 24 h após foram sacrificados e a bolsa foi aberta e lavada com 1 ml de salina estéril. Os parâmetros inflamatórios observados foram: acúmulo de leucócitos, exsudação, atividade da mieloperoxidase (MPO) e da adenosina-deaminase (ADA), concentração de nitrato/nitrito (NOx) e níveis de fator de necrose tumoral alfa (TNF- ), interleucina-1 beta (IL-1 ) e quimiocina para neutrófilo (KC) foram avaliados 24 h depois. Para avaliar a exsudação, 1 h antes da Cg foi administrado 0,2 ml de azul de Evans (25 mg/kg, i.v.). Para determinação da curva dose e tempo resposta, inicialmente diferentes grupos de animais receberam diferentes doses de tacrolimus (1 a 10 mg/kg, v.o.) 0,5 h antes da injeção de carragenina e a migração celular e a exsudação foram avaliadas 24 h após. Em outros experimentos, diferentes grupos receberam uma única dose de tacrolimus (2 mg/kg, v.o.) em diferentes períodos de tempo (0,5 - 4 h) e os parâmetros inflamatórios foram avaliados 24 h após. De acordo com este protocolo, tacrolimus (2 mg/kg, v.o.) administrado 0,5 h antes da Cg, foi utilizado para analisar o seu efeito sobre a atividade de MPO e ADA e níveis de NOx, TNF- , IL-1 e KC. A indometacina (5 mg/kg, i.p.) e a dexametasona (0,5 mg/kg, i.p.) foram utilizadas como fármacos de referência. Os resultados foram expressos como média ± erro padrão da média. As diferenças estatísticas foram determinadas pela análise de variância (ANOVA), seguido de teste de Dunnett ou teste t de Student. Valores de P < 0,05 foram considerados significantes. Resultados: O tacrolimus (Tac: 2 mg/kg, v.o.) inibiu o acúmulo de leucócitos e de neutrófilos e reduziu a exsudação, os níveis de TNF- , IL-1, KC e óxido nítrico, além da atividade da MPO e da ADA (P < 0,05). Conclusão: Estes resultados demonstram que o tacrolimus apresenta importante atividade antiinflamatória, similar a da indometacina e da dexametasona. A inibição de citocinas pró-inflamatórias (TNF- , IL-1, KC), enzimas (MPO e ADA) e liberação de mediadores inflamatórios (NOx) parecem fazer parte da atividade antiinflamatória do tacrolimus.
17

ANALYSIS OF CYCLOSTATIONARY AND SPECTRAL CORRELATION OF FEHER-KEYING (FK) SIGNALS

Chang, Soo-Young, Gonzalez, Maria C., McCorduck, James A., Feher, Kamilo 10 1900 (has links)
International Telemetering Conference Proceedings / October 21, 2002 / Town & Country Hotel and Conference Center, San Diego, California / Feher Keying (FK) signals are clock shaped baseband waveforms with the potential to attain very high spectral efficiencies. Two FK signals which have different level rectangular waveforms (named as FK-1) or sinusoidal waveforms (named as FK-2) for two binary symbols are considered in this paper. These signals have periodic components in the time domain. Therefore they have cyclostationary properties. This means that spectral correlation exists in the frequency domain. For each type of waveforms, spectral correlation has been investigated. FK signals can be expressed mathematically into two parts in the frequency domain – discrete part and continuous part. The discrete part has one or more discrete impulse(s) in their spectra and the continuous part has periodically the same shape of harmonics in their spectra. The correlations of their spectra have been obtained mathematically and by simulation. It is shown that FK signals have high correlation related to the symbol rate. Finally, some suggestions how these properties can be used to improve their performance by devising better demodulators are discussed. These properties can be used for interference rejection at the receiver, which results in low bit error rate performance.
18

Test and Evaluation of Ultra High Spectral Efficient Feher Keying (FK)

Lin, Jin-Song, Feher, Kamilo 10 1900 (has links)
International Telemetering Conference Proceedings / October 22-25, 2001 / Riviera Hotel and Convention Center, Las Vegas, Nevada / Performances of a subclass of a new spectral efficient modulation scheme, designated as Feher Keying [1], or FK, is evaluated. The Power Spectral Density (PSD) and Bit Error Rate (BER) characteristics of FK are presented. FK has ultra high spectral efficiency and satisfies the frequency mask for WLAN defined in FCC part 15, and it has a simple structure for high bit rate implementation.
19

Philoponus on topos

Papachristou, Ioannis 06 December 2017 (has links)
Die Dissertation versucht einerseits die Form, die Methode und die Struktur von Philoponos Kommentar zur Physik neu zu interpretieren und andererseits seine Theorie des Ortes (Topos) eingehend zu untersuchen. Das Buch besteht aus fünf Kapiteln und es enthält ein Vorwort, einen Epilog und ein Literaturverzeichnis. Philoponus schlägt eine doppelte Ortsbestimmung vor. Er unterscheidet zwischen dem Ort, der leer ist, der dreidimensionalen Erweiterung, die sich ontologisch von Körpern unterscheidet, und dem Begriff des Ortes, der von Körpern erfüllt wird. Philoponos strebt danach die Beziehung zwischen dem Ort und dem Körper neu zu definieren und unterstreicht den ontologischen Unterschied, den eine körperlose Erweiterung von einer körperlichen Erweiterung haben sollte. Die Arbeit konzentriert sich auch auf Philoponos Kritik an der Definition von Ort laut Aristoteles und an der Peripatetischen Tradition (Eudemos, Themistios) bezüglich des Ortes des Himmels. Abschließend kommt das Buch zu dem Schluss, dass Philoponos Strategie sowohl in den Exkursen des Kommentars als auch in gewissen Teilen seiner Exegese in drei Stufen dargestellt werden kann: Er weist erstens die Gültigkeit der Kritik von Aristoteles und Themistios gegen das Konzept der lokalen Erweiterung zurück; zweitens greift er die aristotelische Definition des Ortes an, indem er seine Schwächen und Unstimmigkeiten mit der Natur der Dinge zeigt; und drittens stellt er seine eigene Theorie des Ortes dar. Das Ergebnis ist ein wertvolles Argumentarium über den Ort und ein wichtiger Beitrag für die Physik der Spätantike. / The dissertation attempts to interpret afresh, on the one hand, the form, methodology and structure of Philoponus’ commentary on the Physics and, on the other hand, to study in depth his theory of place (topos). The book extends over five chapters and includes a preface, an epilogue and a bibliography. Philoponus attempts a double determination of place. He distinguishes between the place which is void, three-dimensional extension that is ontological different from bodies, and the concept of place that is filled by bodies. Philoponus wishes to redefine the relationship between place and body and he underlines the ontological difference that a bodiless extension should have from a bodily extension. The thesis also focuses on Philoponus’ critique of Aristotle’s definition of place and the Peripatetic tradition (Eudemus, Themistius) regarding the place of the heavens. The book concludes that, Philoponus’ strategy in the digressions of the commentary, but also in certain parts of his exegeses, can be seen in three stages: first, he repudiates the cogency of Aristotle’s and Themistius’ critique to the concept of local extension; second, he attacks the Aristotelian definition of place by showing its weaknesses and inconsistencies with the nature of things; and third, he establishes his own theory of place. The result is a valuable set of arguments regarding place and a major contribution to the physics of late antiquity.
20

Economically beneficial drug interactions with cyclosporin and tacroliumus : clinical studies in recipients of kidney and liver transplants

Jones, Terence Edward. January 2000 (has links) (PDF)
Bibliography: leaves 234-257. Three separate clinical studies in organ transplant recipients are presented. The aims are to examine fundamental questions regarding the clinically and economically important pharmokinetic interaction between diltiazem and cyclosporin, an interaction widely utilised in organ transplantation. The data contained should assist the development of soundly based policies that will ensure a benefit exists before a sparing agent is coprescribed, and that the lowest effective dose of sparing agent is used.

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