Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-08-09T23:58:08Z No. of bitstreams: 1 AdrianaSoeiroDeFariasSilvaJunqueiraAyres_TESE.pdf: 4492005 bytes, checksum: 363e585cddc1b3b004eb5170356b575b (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-08-15T23:16:31Z (GMT) No. of bitstreams: 1 AdrianaSoeiroDeFariasSilvaJunqueiraAyres_TESE.pdf: 4492005 bytes, checksum: 363e585cddc1b3b004eb5170356b575b (MD5) / Made available in DSpace on 2016-08-15T23:16:31Z (GMT). No. of bitstreams: 1 AdrianaSoeiroDeFariasSilvaJunqueiraAyres_TESE.pdf: 4492005 bytes, checksum: 363e585cddc1b3b004eb5170356b575b (MD5) Previous issue date: 2015-12-11 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / As plantas medicinais constituem uma rica fonte de compostos biologicamente ativos com seu potencial terap?utico para o tratamento de diversos transtornos psiqui?tricos, como os transtornos de ansiedade e depress?o. O transtorno de ansiedade generalizada tem aumentado de forma significativa, sendo o segundo transtorno mais prevalente em locais de assist?ncia ? sa?de p?blica. A depress?o ? considerada um transtorno psiqui?trico cr?nico e comum que afeta 350 milh?es de indiv?duos de todas as idades ao redor do mundo. Neste contexto as condutas de interven??o farmacol?gica que v?m sendo empregadas, embora eficazes, deixam a desejar, quando observados seus efeitos adversos. A Passiflora ? uma variedade comumente conhecida comercialmente, mas tamb?m ? usada na medicina tradicional brasileira. A Passiflora edulis exibe consider?vel variabilidade morfol?gica. Esta planta produz dois tipos de fruto: o roxo (P. edulis var. edulis) e o amarelo (P. edulis var. flavicarpa). O presente estudo investigou os efeitos centrais do extrato aquoso das folhas de duas variedades da esp?cie Passiflora edulis em testes comportamentais utilizados para avaliar comportamentos relacionados ? ansiedade e depress?o, bem como investigou o potencial efeito do tipo antidepressivo das subfra??es da Passiflora edulis var. edulis e os mecanismos neurofarmacol?gicos respons?veis por essa a??o. Para a realiza??o desse estudo foram utilizados camundongos Swiss machos (2 meses de idade, pesando 30-35 g). Os animais receberam o extrato aquoso das folhas das duas esp?cies de Passiflora: Passiflora edulis Sims var. edulis (PEE - 100, 300, 1000 mg/Kg) e subfra??es AcOet, BuOH e residual (25, 50, 75, 100 mg/Kg), e a P. edulis var. flavicarpa (PEF - 30, 100, 300, 1000 mg/Kg) ou solu??o salina, por gavagem, 60 minutos antes dos testes do labirinto em cruz elevado (LCE), teste de campo aberto (TCA), teste de nata??o for?ada (TNF) e teste de seda??o induzido por tiopental. Para investigar o mecanismo de a??o da atividade do tipo antidepressiva das subfra??es foram utilizadas as seguintes drogas: PCPA (inibidor da s?ntese de 5-HT), AMPT (inibidor da s?ntese de catecolaminas), DSP-4 (neurotoxina noradren?rgica) e Sulpiride (antagonista seletivo de receptor dopamin?rgico D2). Foram utilizados como controle positivo padr?o, a fluoxetina e a nortriptilina. Os resultados do perfil fitoqu?mico demonstram caracter?sticas bem distintas para o extrato aquoso das variedades de P. edulis ?flavicarpa? e ?edulis?. Os extratos aquosos de ambas as variedades de P. edulis compartilham atividade do tipo ansiol?tica (PEE 300 mg/Kg; PEF 300 e 1000 mg/Kg) e antidepressiva (PEE 300 mg/Kg; PEF 1000 mg/Kg), enquanto o efeito hipolocomotor/sedativo s? foi visto para a PEE (1000 mg/Kg). Ambas subfra??es AcOet e BuOH do extrato aquoso da PEE apresentaram atividade do tipo antidepressiva na dose de 50 mg/Kg no TNF. Os dados sugerem que o efeito do tipo antidepressivo das subfra??es da P. edulis envolve a neurotransmiss?o serotonin?rgica e catecolamin?rgica, principalmente dopamin?rgica, haja visto que o pr?-tratamento com DSP-4 n?o afetou a a??o antidepressiva das subfra??es, enquanto que mostrou ser dependente da ativa??o de receptores dopamin?rgicos D2. / The medicinal plants constitute a rich source of biologically active compounds used for the treatment of many psychiatric disorders, such as anxiety disorders and depression. Generalized anxiety disorder has increased significantly, being the second most prevalent disorder in care facilities to public health. Depression is considered a chronic and common psychiatric disorder that affects 350 million people of all ages around the world. In this context, the pharmacological intervention conduits have been employed, effective, although leave to be desired when observed adverse effects. The genus Passiflora is commonly commercially known by its fruit, but is also widely used in traditional Brazilian medicine. Passiflora edulis displays considerable morphological variability. This plant produces two types of fruit: Purple (Passiflora edulis Sims fo. edulis) and yellow (Passiflora edulis fo. flavicarpa Degener). This study investigated the central effects of aqueous extract of the leaves of the two varieties of the species Passiflora edulis in tests used to assess behavior related to anxiety and depression, as well as investigating the potential effect of the antidepressant-like fractions of edulis fo. edulis and neuropharmacological mechanisms responsible for this action. To conduct this study used male Swiss mice (2 months old, weighing 30-35 g). The animals received the aqueous extract of the leaves of the two species of Passiflora: edulis fo. edulis (100, 300, 1000 mg / kg) and fractions ethyl acetate, butanol and aqueous waste (25, 50, 75, 100 mg / kg) and edulis fo. flavicarpa (30, 100, 300, 1000 mg / kg) or saline by gavage 60 minutes prior to the maze tests at high cross the open field test, test forced swim test and sedation induced by thiopental. To investigate the mechanism of action of the activity of antidepressant type of fractions the following drugs were used: PCPA (inhibitor of 5-HT synthesis) AMPT (inhibitor of catecholamine synthesis), DSP-4 (noradrenergic neurotoxin) and Sulpiride (antagonist selective dopamine D2 receptor). They were used as a standard positive control, fluoxetine and nortriptyline. The results of the phytochemical profile show very different characteristics to the aqueous extract of the varieties of Passiflora edulis "flavicarpa" and "edulis". The aqueous extracts of both varieties of Passiflora edulis share anxiolytic activity type (edulis fo. edulis 300 mg/kg; edulis fo. flavicarpa 300 and 1000 mg/kg) and antidepressant (edulis fo. edulis 300 mg/kg; edulis fo flavicarpa 1000 mg/kg), while the effect hipolocomotor/sedative was only seen for edulis fo. edulis (1000 mg/kg). Both fractions ethyl acetate, butanol aqueous extract edulis fo. edulis showed activity type antidepressant at a dose of 50 mg/kg in the forced swim test. The data suggest that the effect of antidepressant-like fractions edulis fo. edulis involves catecholaminergic and serotonergic neurotransmission, particularly dopaminergic, there is seen that pre-treatment DSP-4 is not affected antidepressant action of fractions as was dependent activation of dopamine D2 receptors.

Made available in DSpace on 2014-12-17T15:15:02Z (GMT). No. of bitstreams: 1 HumbertoSG_DISSERT.pdf: 1623099 bytes, checksum: 9db2624a800c722b68b561bc7a9bc747 (MD5) Previous issue date: 2013-04-01 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / Nesta disserta??o, uma revis?o sobre tr?s modelos cosmol?gicos n?o-padr?o do tipo Friedmann-Robertson-Walker s?o apresentados. O modelo !CDM, o g?s de Chaplygin generalizado e o modelo de brana de Dvali-Gabadadze-Porrati (DGP). Apresentamos tamb?m, tr?s testes estat?sticos utilizados em Cosmologia, cada um envolvendo uma vela padr?o diferente. Estes testes t?m como objetivo, vincular os diferentes par?metros de cada modelo e assim compar?-los com os dados observacionais mais atuais. Efetuamos o teste do m?dulo de dist?ncia de Supernovas do tipo Ia, atrav?s de 580 Supernovas do Union Compilation 2.1 (2011) [1]. A Fra??o de massa de aglomerados de gal?xias, onde utilizamos um conjunto de 52 aglomerados observados pelo CHANDRA (2009) [2] e a raz?o CMB/BAO, onde foram utilizados um conjunto de 6 picos de BAO do WiggleZ Dark Energy Survey (2011) [3]. Esses testes foram aplicados para cada um dos modelos apresentados. Verificamos que individualmente, os testes cosmol?gicos n?o s?o bons o suficiente para vincular modelos, criando espa?os param?tricos degenerados, necessitando de uma an?lise em conjunta dos testes para vincular os par?metros. OBS: N?o foi poss?vel efetuar a descri??o integral do resumo, devido o fato do sistema utilizado n?o aceitar os s?mbolos existentes. Desse modo, solicitamos que a visualiza??o desse elemento seja efetuada no arquivo da disserta??o.

This is a case study of tourism policies made around the Satpura Tiger Reserve in Madhya Pradesh, India. The purpose of this study is to analyse the state tourism policies in Madhya Pradesh. The study is divided in two parts, the first part analyses the state tourism policies using Foucault’s governmentality theory. The governmentality theory is used to expose the ideas in the policies with consideration to neoliberalism and the local communities. The first part also examine the ideas of inclusion of the local communities in tourism. The second part are interviews with officials and semi-officials that are implementing the policies. The local communities are the focus in this study since tourism is marketed as a solution to economic growth and employment. Therefore, one of the aspects is if the local communities are a resource in the development of tourism, and if there is any obstacles for the local communities to participate in the tourism industry. The material used is state tourism policies from 2005 and 2016. Interviews were conducted in Pachmarhi, Madhai, Soghagpur, Pipariya and Bhopal. The conclusion is that the state tourism policy from 2016 is clearly neo-liberal that the market and the government is clearly in concurrence. When it comes to the local communities the main problem for participation is that most of the local communities lack of skills, however the type of tourism were the local communities could be beneficiaries is not the tourism that the state government is developing.

No description available.

This study examines the relationship between ethics of Artificial Intelligence and the design and implementation process of Artificial Intelligence in Business Intelligence. In doing so, I compare the current ethical knowledge in AI with AI users and researchers experiences. This is based on three fields; Key activities for successful implementation, outcome effects of laws and regulations, and ethical analysis of data. The results of the study confirms existing theories about why AI projects might fail, but expands and develops the complexity of Artificial Intelligence in an ethical aspect. / Den här studien undersöker förhållandet mellan etik inom Artificiell Intelligens och designen och implementationen av Artificiell Intelligens inom Business Intelligence. För att göra detta jämför jag den existerande kunskapen om etik inom AI med användare och forskare inom AI. Studien är baserad på tre områden, huvudaktiviteter för lyckad implementation, effekterna av lagar och regleringar, och etisk analys av data. Resultaten bekräftar existerande teorier, men expanderar och utvecklar komplexiteten av AI i en etisk aspekt.

This essay reflects a particular method and way of working that I employ when undertaking artistic research. My artworks are rooted and develop from the situation I find myself in as an artist, the very context I exhibit the work within. I do this by trying to understand this position, both on the micro and macro scale. As an artist currently studying at—and subsequently exhibiting in relation to— Konstfack, I base my research with the physical manifestation of the school. An imposing building that was part of a huge headquarters and factory site for the telecommunication company, Ericsson, in south Stockholm. The title of my essay is from the translation of a unique German cipher machine, the Geheimschreiber, made known to me through enquiry into this site. Throughout the Second World War the German army used this machine to send highly encrypted military messages across Swedish telephone cables. Following one of the greatest accomplishments in the history of cryptography, a Swedish mathematician broke this German code and subsequently assisted in designing a deciphering machine on behalf of the Swedish Intelligence branch. This device, known as the App, was secretly developed and manufactured by Ericsson, possibly where I now study. In exploring the theme of secrets, this essay originates from an underpinning desire and subject of my work to reveal what is concealed or overlooked. Through researching and writing this essay I attempt to have a better understanding on the notion of secrets, in both the private and public realms. Introducing the artistic process and situation I am working from, I explore the central role that secrets play within society. In order to understand secrecy today I introduce the intertwined and associated contemporary debates of privacy, (both private and public) and transparency through such subjects as Google’s new privacy policy, mobile phone hacking, WikiLeaks and offshore banking.

Il tribalismo costituisce una caratteristica intrinseca delle società mediorientali, concorrendo insieme a cultura araba e religione islamica a comporne l’identità. In Iraq, da sempre, il tribalismo ha costituito sia una struttura organizzativa ed una modalità di relazione sociale, che una dinamica di potere. Durante il Mandato britannico e la monarchia, la manipolazione politica di cultura e strutture tribali ha rafforzato la legittimazione del governo; nella fase repubblicana, con l’emergere delle forze armate quale principale attore politico e l’impatto con la modernità, il tribalismo si è trasformato pur rimanendo radicato nella società. Nella fase iniziale del regime ba’thista, la cultura tribale è stata combattuta essendo considerata un retaggio arcaico. Senonchè, con le difficoltà legate alla guerra con l’Iran, l’invasione del Kuwait e il successivo embargo, il regime di Saddam Hussein sfruttò proprio il tribalismo sia come dinamica di presa e controllo del potere che come collante propagandistico e sociale. Nel vuoto politico seguito al crollo del regime, le tribù riemersero come “campo di battaglia” tra insurgency e forze della Coalizione. Con il Surge americano e la nascita della Sahwa quale reazione allo stragismo jihadista, le tribù hanno impresso una svolta che ha salvato il paese dalla guerra settaria. Anche al Maliki ha saputo abilmente avvantaggiarsi del fenomeno tribale. Oggi le tribù continuano a rappresentare sia una constituency imprescindibile per ogni partito politico, che una diversificata e trasversale forza politica attiva. / Tribalism is an intrinsic character of Middle Eastern’s societies, as it contributes, together with Arab culture and Islamic religion, to shape their identity. In Iraq, since ever, tribalism constituted an organizational structure and a pattern of social relations, as well as dynamic of power’s exercise. Under the British Mandate and the Monarchy, politic manipulation of tribal’s culture and structures strengthened government’s legitimation; during the Republican period, as the Army emerged as main political driver and the influence of Modernity, tribalism transformed itself even if its presence into the society was still very strong. In the initial phase of Ba’thist’s regime, tribal culture was opposed, since it was considered as an obsolete heritage. But, facing the difficulties stemming from the war with Iran, the invasion of Kuwait and the embargo, the regime of Saddam Hussein exploited tribalism as a dynamic of power’s control, as well as propaganda and social bond. In the political void ensuing to the collapse of the regime, the tribes surfaced as “battlefield” between insurgency and Coalition’s Forces. American Surge and the tribes’ intervention in the Sahwa, as a reaction to jihadist’s bloodbath, avoided a sectarian civil war. Also al Maliki was able to exploit the tribal system. Nowadays, tribes are still an invaluable constituency for every political party, as well as diversified and a cross-parties political force.

本研究的目的在探討台灣貨幣市場短天期利率衍生性金融商品（30天期商業本票利率期貨、90天遠期利率協定〈以下簡稱FRA〉）對其即期利率（30天期商業本票利率、90天期商業本票利率）之『價格發現』功能。可由兩方面來檢定利率遠期協定或利率期貨市場之『價格發現』功能：（1）市場效率性：FRA、利率期貨價格可否作為未來到期日時即期利率之不偏預期；（2）FRA、利率期貨與即期利率價格間之領先-落後關係。 選取各交易日的日資料作為觀察值。在研究方法上採用ADF單根檢定、效率性檢定、向量自我相關模型（VAR）、Granger因果關係檢定、誤差正交檢定、共整合檢定、誤差修正模型。 結論結果發現，90天遠期利率協定（FRA）對90天期商業本票利率進行『價格發現』的分析，以「市場效率性檢定」的結果顯示此市場無效率，亦即無『價格發現』，可能是因為買FRA的機構投資人目的不是持有到到期，僅為判斷短期利率走勢方向，可能買個幾天欲賺取差價利潤，所以非為未來現貨價格的不偏預期；以「領先-落後關係分析」，顯示其無『價格發現』，此一結果的可能解釋是由於台灣FRA市場非集中市場公開交易，交易量尚不及現貨市場。因此市場資訊的不透明可能使遠期契約價格不如現貨價格般具代表性。 30天期商業本票利率期貨對30天期商業本票利率進行『價格發現』的分析，以「市場效率性檢定」結果顯示在到期日前適當的期間（24~36天）此市場具有效率性，即存在『價格發現』；而「領先-落後關係分析」結果則無明顯的領先落後，不具有期貨領先現貨的『價格發現』，此部分我們可能提出的解釋為：在30天期商業本票利率期貨剛推出不久，一般市場上的交易者大多是從事避險交易，鮮少進行投機行為，所以不具有短天的領先落後關係，其顯示價格發現是在考慮市場存在風險溢酬下，到期前24~36天的利率期貨價格是未來現貨價格的預期。