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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 151 to 160 of 162 (0.015 seconds)Spelling suggestions: "subject:"gehirn"" "subject:"endhirn""
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Establishment of retinoic acid gradients in the early development of Xenopus laevis / Etablierung von Retinsäure Gradienten in der Frühentwicklung von Xenopus laevisStrate, Ina 27 April 2009 (has links)
No description available.
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| 152 |
Molecular Studies on Head Development of the Amphipod Crustacean Parhyale hawaiensis / Molekulare Untersuchungen zur Kopfentwicklung des amphipoden Krustazeen Parhyale hawaiensisSchmid, Bernhard 05 July 2011 (has links)
No description available.
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| 153 |
Functional analysis of embryonic brain development in Tribolium castaneum / Funktionale Analyse zur embryonalen Gehirnentwicklung in Tribolium castaneumKoniszewski, Nikolaus 22 August 2011 (has links)
No description available.
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| 154 |
Comparison of expression pattern and localization of iron transport proteins in rat liver, brain and spleen during acute phase response:invivo and invitro studies / Vergleich der Expressionsmuster und Lokalisierung von Eisentransportproteine Ratte in Leber, Gehirn und Milz während der Akutphase-Antwort: In-vivo-und In-vitro-StudienNaz, Naila 12 January 2012 (has links)
No description available.
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| 155 |
Intrakranielle Volumenänderungen im Magnetresonanztomogramm (MRT) und neuropsychologische Veränderungen bei Patienten mit MCI (Mild Cognitive Impairment) / Cerebral volume alterations in MRI (Magnetic Resonance Imaging) and neuropsychological alterations in patients with MCI (Mild Cognitive Impairment)Dörnte, Jan 07 November 2007 (has links)
No description available.
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| 156 |
Modelling cortical laminae with 7T magnetic resonance imagingWähnert, Miriam 28 January 2015 (has links) (PDF)
To fully understand how the brain works, it is necessary to relate the
brain’s function to its anatomy. Cortical anatomy is subject-specific. It is character-
ized by the thickness and number of intracortical layers, which differ from one cortical
area to the next. Each cortical area fulfills a certain function. With magnetic res-
onance imaging (MRI) it is possible to study structure and function in-vivo within
the same subject. The resolution of ultra-high field MRI at 7T allows to resolve
intracortical anatomy. This opens the possibility to relate cortical function of a sub-
ject to its corresponding individual structural area, which is one of the main goals of
neuroimaging.
To parcellate the cortex based on its intracortical structure in-vivo, firstly, im-
ages have to be quantitative and homogeneous so that they can be processed fully-
automatically. Moreover, the resolution has to be high enough to resolve intracortical
layers. Therefore, the in-vivo MR images acquired for this work are quantitative T1
maps at 0.5 mm isotropic resolution.
Secondly, computational tools are needed to analyze the cortex observer-independ-
ently. The most recent tools designed for this task are presented in this thesis. They
comprise the segmentation of the cortex, and the construction of a novel equi-volume
coordinate system of cortical depth. The equi-volume model is not restricted to in-
vivo data, but is used on ultra-high resolution post-mortem data from MRI as well.
It could also be used on 3D volumes reconstructed from 2D histological stains.
An equi-volume coordinate system yields firstly intracortical surfaces that follow
anatomical layers all along the cortex, even within areas that are severely folded
where previous models fail. MR intensities can be mapped onto these equi-volume
surfaces to identify the location and size of some structural areas. Surfaces com-
puted with previous coordinate systems are shown to cross into different anatomical
layers, and therefore also show artefactual patterns. Secondly, with the coordinate
system one can compute cortical traverses perpendicularly to the intracortical sur-
faces. Sampling intensities along equi-volume traverses results in cortical profiles that
reflect an anatomical layer pattern, which is specific to every structural area. It is
shown that profiles constructed with previous coordinate systems of cortical depth
disguise the anatomical layer pattern or even show a wrong pattern. In contrast to
equi-volume profiles these profiles from previous models are not suited to analyze the
cortex observer-independently, and hence can not be used for automatic delineations
of cortical areas.
Equi-volume profiles from four different structural areas are presented. These pro-
files show area-specific shapes that are to a certain degree preserved across subjects.
Finally, the profiles are used to classify primary areas observer-independently.
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| 157 |
Anatomische Zuordnung tiefer Hirnstrukturen auf hochauflösenden MRT-Aufnahmen fixierter Gehirnproben / Anatomical assignment of deep brain structures on high-resolution MRI images of fixed brain specimensStärker, Katrin 14 August 2017 (has links)
No description available.
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| 158 |
Interindividual Differences in Mid-Adolescents in Error Monitoring and Post-Error AdjustmentRodehacke, Sarah, Mennigen, Eva, Müller, Kathrin U., Ripke, Stephan, Jacob, Mark J., Hübner, Thomas, Schmidt, Dirk H. K., Goschke, Thomas, Smolka, Michael N. 14 July 2014 (has links)
A number of studies have concluded that cognitive control is not fully established until late adolescence. The precise differences in brain function between adults and adolescents with respect to cognitive control, however, remain unclear. To address this issue, we conducted a study in which 185 adolescents (mean age (SD) 14.6 (0.3) years) and 28 adults (mean age (SD) 25.2 (6.3) years) performed a single task that included both a stimulus-response (S-R) interference component and a task-switching component. Behavioural responses (i.e. reaction time, RT; error rate, ER) and brain activity during correct, error and post-error trials, detected by functional magnetic resonance imaging (fMRI), were measured. Behaviourally, RT and ER were significantly higher in incongruent than in congruent trials and in switch than in repeat trials. The two groups did not differ in RT during correct trials, but adolescents had a significantly higher ER than adults. In line with similar RTs, brain responses during correct trials did not differ between groups, indicating that adolescents and adults engage the same cognitive control network to successfully overcome S-R interference or task switches. Interestingly, adolescents with stronger brain activation in the bilateral insulae during error trials and in fronto-parietal regions of the cognitive control network during post-error trials did have lower ERs. This indicates that those mid-adolescents who commit fewer errors are better at monitoring their performance, and after detecting errors are more capable of flexibly allocating further cognitive control resources. Although we did not detect a convincing neural correlate of the observed behavioural differences between adolescents and adults, the revealed interindividual differences in adolescents might at least in part be due to brain development.
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| 159 |
GehirnforschungPalm, Kerstin 27 April 2017 (has links)
Gehirnforschung ist ein naturwissenschaftlicher Forschungsbereich, der sich aus den Disziplinen Anatomie, Embryologie, Physiologie, Pharmakologie und Psychologie entwickelt hat. Gendertheoretisch informierte historische Studien zur Gehirnforschung fokussieren ideologiekritische und diskursanalytische Betrachtungen androzentrischer bzw. sexistischer Körpervorstellungen von der Antike bis zum 21. Jh., welche u. a. die bürgerliche Geschlechterordnung argumentativ gestützt und naturalisiert hatten.
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| 160 |
The role of pou2/spiel-ohne-grenzen (spg) in brain and endoderm development of the zebrafish, Danio rerioReim, Gerlinde 12 August 2003 (has links)
The central theme of development, how cells are organized into functional structures and assembled into whole organisms, is addressed by developmental biology. One important feature of embryonic development is pattern formation, which is the generation of a particular arrangement of cells in three-dimensional space at a given point of time. Central to this work is the model system of the zebrafish, Danio rerio. The aim of the first part of this study was to try to understand how a distinct part of the embryonic brain called midbrain-hindbrain boundary (MHB), a region that acts as an organizer for the adjacent brain regions, is established in vertebrates. spiel-ohne-grenzen (spg) is one mutant which interferes with MHB development. Here, I addressed the role of pou2 in brain development by molecular, phenotypical and functional analysis. By genetic complementation and mapping I could elucidate the molecular nature of this mutant and found that the pou2 gene encoding the POU domain transcription factor is affected in spg mutant embryos. By chromosomal syntenic conservation, phylogenetic sequence comparison, and expression and functional data I imply that pou2 is the orthologue of the mammalian Oct4 (Pou5F1) gene. I find by detailed expression and transplantation analysis that pou2 is cell autonomously required within the neuroectoderm to activate genes of the MHB and hindbrain primordium, like pax2.1, wnt1, gbx2 or krox20. By gain-of-function experiments I demonstrate that pou2 synergizes with Fgf8 signaling in order to activate particularly the hindbrain primordium. Since pou2 is already provided to the embryo by the mother, I generated embryos which lack maternal and zygotic pou2 function (MZspg) to reveal a possible earlier than neuroectodermal role of pou2. In the second part of this work I demonstrate that pou2 is a key factor controlling endoderm differentiation. By expression and gain-of-function analysis I suggest a cell autonomous function for Pou2 in the first step of endodermal differentiation. By gain-of-function experiments involving the gene encoding the HMG transcription factor Casanova (Cas) I show that both Cas and Pou2 are necessary to activate expression of the endodermal differentiation marker sox17 in a mutually dependent way, and that the ability of Cas to ectopically induce sox17 strictly requires Pou2. I conclude that both maternal and zygotic pou2 function is necessary for commitment of endodermal progenitor cells to differentiate into endodermal precursor cells.
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