Th. doct.--Universität Bern, 1998. / Bibliogr. p. [479]-495. Index.

A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine. / compression of the right atrium and ventricle yet their LV function is within normal range. In the setting of normal LV function, symptomatic PE could potentially be the result of right heart compression causing right heart strain. Emphasis should therefore be placed on analyzing the presence and degree of right heart strain in patients with symptomatic pectus excavatum. When assessing for a correlation between the HI, CI, DI, or CCI together and independently with cardiopulmonary impairment, no significant relationships were identified. While it would be highly advantageous for a PE severity index to correlate with objective physiologic impairment, our data suggest that the currently defined indices fail to do so. Data confirming such a correlation would provide a means to measure both the severity of deformity and changes in functional disability in patients with PE. We aim to analyze the correlation between the HI and three new indices with cardiopulmonary impairment using the cardiopulmonary exercise test (CPET). In this study we evaluated the correlation of the Haller, correction, depression, and cardiac compression indices with functional cardiopulmonary impairment using preoperative cardiopulmonary exercise test (CPET) data. We hypothesize that the correction and cardiac compression indices will be strongly correlated with physiologic impairment in patients with PE, thus providing a novel means to measure functional disability as a function of disease severity. Study Design This is a retrospective study of 71 children between the ages of birth and 18 years of age who underwent evaluation for corrective surgery for pectus excavatum between 2010 and 2016 at Phoenix Children’s Hospital. Our final sample underwent preoperative computed tomography (CT) or MRI scan results as well as cardiopulmonary exercise testing. For each patient, the HI, CI, DI, and CCI were independently assessed using the PACS System by a single rater. Preoperative functional capacity was determined by measurement of peak oxygen consumption (VO2max reported as percent predicted) and stroke volume (a surrogate for cardiac output) which was assessed via the O2 pulse (VO2max/heart rate) reported as percent predicted. The possible values range from zero to 100% of the predicted value. Assessments Halller Index Correction Index Depression Index Cardiac Compression Index Correction, Depression, Cardiac Compression and Haller Indices Fail to Correlate with Cardiopulmonary Impairment in Pectus Excavatum Abstract Results Background: Pectus excavatum (PE) affects 1 in every 300 to 1,000 live births with a male to female ratio of 5:1, making it the most common congenital chest wall deformity in children. The standard for determining disease severity has become the Haller Index, which has been shown to poorly correlate with physiologic impairment. Recently, more novel indices have been introduced in an effort to more effectively represent disease burden. We aim to analyze the correlation between these indices and cardiopulmonary impairment in patients with PE using chest CT/ MRI as well as preoperative cardiopulmonary exercise testing data. Conclusions: We found that when assessing for a correlation between the HI, CI, DI, or CCI together and independently with cardiopulmonary impairment, both the linear and multiple regression models failed to identify a statistically significant relationship. While it would be highly advantageous for a PE severity index to correlate with objective physiologic impairment, our data suggest that the currently defined indices fail to do so.

Le médecin bernois Albrecht von Haller (1708-1777) est une figure centrale de l'espace des Lumières germaniques et helvètes. Auteur d'une oeuvre pluridisciplinaire, il polarise un vaste réseau de correspondants dans toute l'Europe. Nous nous proposons donc d'analyser son rôle de médiateur privilégié dans le transfert d'idées savantes entre les espaces français et germaniques. En procédant à des échanges de livres et en rédigeant de très nombreuses recensions, Haller lit de façon critique la production de la scène intellectuelle française. Il en diffuse et en commente les résultats dans le monde germanophone et dans l'ensemble de son réseau épistolaire. Les membres du réseau français de Haller sont aussi les médiateurs de sa pensée auprès des cercles éclairés français : ils sélectionnent dans ses oeuvres des éléments intellectuels qui correspondent à leurs attentes et les importent dans le but d'enrichir leurs propres écrits. / The Bernese doctor Albrecht von Haller (1708-1777) is a central figure in the Germanic and Helvetian period of Enlightenment. Author of a multidisciplinary work, he attracts a vast amount of correspondents all over Europe. Consequently, we suggest to analyse his role as a privileged mediator in the transfer of scholar ideas between the French and Germanic spheres. Through exchanging books and doing a lot of recensions, Haller has a critical reading of the French intellectual scene's productions. He edits and comments his results in the Germanic world and in the whole of his epistolary network. The members of the French Haller network are also mediators of his views within the French enlightened circle: They select intellectual elements in his work which correspond to their own expectations and incorporate them in to their own writings in order to enrich them.

Haller was, by any standard, a very prolific writer, not only of letters. He published 24 books in 50 volumes, many of which he reworked for second editions; he wrote 450 essays, 9000 book reviews, and edited another 52 volumes. Of his letters exchanged with 1139 male and 50 female correspondents, close to 17,000 have survived.

Haller was, by any standard, a very prolific writer, not only of letters. He published 24 books in 50 volumes, many of which he reworked for second editions; he wrote 450 essays, 9000 book reviews, and edited another 52 volumes. Of his letters exchanged with 1139 male and 50 female correspondents, close to 17,000 have survived.

Photocopy of typescript. / Digitized by Kansas Correctional Industries

La maintenance des voies navigables par dragage génère de grands volumes de sédiments, souvent contaminés en métaux. Pour certains d'entre eux, un traitement par phytoextraction pourrait être envisagé. Le premier volet de ce travail vise à étudier le devenir du Cd présent dans un sédiment de curage contaminé par des métaux lors de la culture d'A. halleri, plante hyperaccumulatrice de Zn et Cd. Pour cela, un suivi des teneurs en Cd a été réalisé dans le sédiment, les parties aériennes de la plante et les lixiviats lors de la culture en pot. La présence de plantes diminue la quantité de Cd lixivié, mais ne modifie ni la fraction échangeable ni le pool phytodisponible en Cd. La spéciation a été étudiée par spectroscopie EXAFS et µXANES, la localisation par µXRF et MEB-EDX, et la biodisponibilité par DGT et extraction au Ca(NO3)2. Avant culture, le Cd est présent sous forme d'un sulfure mixte de Zn, Cd et Fe. Après 5 mois de culture, cette espèce est totalement oxydée en présence de plantes et presque totalement dans les pots sans plante. Les espèces de Cd néoformées sont des complexes Cd-acides organiques et du Cd-phosphate. Le second volet de ce travail porte sur les mécanismes d'accumulation du Cd dans les parties aériennes d'A. halleri. Après culture en hydroponie, l'analyse des parties aériennes par autoradiographie en utilisant 109Cd montre que le métal est transféré aussi bien dans les feuilles jeunes que les matures, ces dernières montrant un enrichissement des tissus périphériques. L'analyse des feuilles par spectroscopie EXAFS a montré que le Cd était lié principalement à des ligands organiques de type COOH/OH, et de façon minoritaire à des ligands de type thiols.

Alljährlich im September bietet Chemnitz ein besonderes Highlight für Buchfreunde: Die Künstlerbuchmesse im Wasserschloss Klaffenbach. "Wozu das?" wird man sich fragen – "Wenn ich ein Buch möchte, gehe ich in einen Laden und kaufe es." Doch auf einer solchen Messe wird keine Massenware geboten, die Drucke, Leporellos und Bücher sind Kunstwerke.

Zugl.: Kairo, Univ., Diss., 1999

Alljährlich im September bietet Chemnitz ein besonderes Highlight für Buchfreunde: Die Künstlerbuchmesse im Wasserschloss Klaffenbach. "Wozu das?" wird man sich fragen – "Wenn ich ein Buch möchte, gehe ich in einen Laden und kaufe es." Doch auf einer solchen Messe wird keine Massenware geboten, die Drucke, Leporellos und Bücher sind Kunstwerke.