Master´s thesis analyses the current state of the production scheduling in a manufacturing company in the automotive industry. It describes the setup system management of the module Advanced Production Planning by Helios Orange program, which company uses. This thesis introduces a new process of order and describes procedures for control of this module. Two essential steps of this new process were tested – creation of production orders and scheduling of production batches. In the end of the master´s thesis there are estimated financial savings after the implementation of the new process production scheduling.

Manufacturing industries used to develop their operation strategies focusing on the cost of manufacturing, high volume production, and stabilizing the customer demand. But due to advancements in technology and evolving customer needs, the market demand became highly volatile, dynamic and customers expected customization, low volume products, and faster deliveries. This evolution in customer needs has pushed the companies to improve their operating systems to be more flexible, agile, and adaptable to the market’s dynamic character. In order to effectively evolves themselves and achieve more flexibility, manufacturing companies had to implement effective manufacturing, planning, and control systems.  The first breakthrough in planning systems came in the year 1975 where a systemic approach called material requirements planning was introduced by Orlicky. MRP has become the global for production planning and inventory management in manufacturing industries. Later, over the years, research on the planning systems has brought modifications in MRP and it was evolved into closed-loop MRP. Further into the late 1980’s availability of technology led to an introduction of a newly evolved system called the Manufacturing resource planning which resulted in a holistic approach in material planning involving, financial and accounting functions which improved the planning efficiency. Further advancement in technology resulted in advanced planning systems like Enterprise resource planning and Advanced planning and scheduling.  On the contrary, though there has been a lot of advancement in technology and effective production planning methods, there are still discrepancies in obtained results when compared to theory. This is because the existing systems were based either solely on push production or pull production strategy. There is a lack of a hybrid system that includes the positives of both production strategies and negates the MRP conflict. However, in the year 2011, a new concept called demand-driven material requirements planning was introduced by Ptak & Smith, which was a fusion of the core MRP, theory of constraints, and Lean principles. Since the introduction DDMRP has seen an increase in implementation across industries which claimed a significant improvement in performance, on-time delivery, reduction in inventory, and reduced stock-outs. DDMRP has received very little attention in academia due to a lack of awareness among researchers and industries. A literature review approach was used to collect and analyze the data on DDMRP and its advantages. The objective of this thesis was to shed light on the process of DDMRP, its pros, and cons in implementing the new material planning system.

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. / Planning of resources is a powerful tool in the field of supply chain management and control and in general. Global large-scale companies and enterprises have this implemented in their planning processes. Today, experts in the subject have found issues regarding the implementation of such tools in small- and medium-sized enterprises (SMEs). Therefore, this paper aims to develop an application for the methodology of continual improvement of processes, referred to as the Deming cycle or Plan–Do–Check–Act (PDCA), which adapts to continuous improvements of processes and products in SMEs. The methodology was modeled in a SME dedicated to manufacture and distribution of wine and products (wine and Pisco). The model was simulated through a simulation software, obtaining results of improvement regarding problems like break of stock, taking into account the satisfaction of the client, productivity in the delivery, and shipment time.

Rätt artiklar, på rätt plats och i rätt tid är viktiga aspekter för ett producerande företag. Det finns olika lagerstyrningsmetoder ett företag kan använda sig av för att säkerställa dessa vilket denna uppsats behandlar. Uppsatsens syfte är att beskriva Thomas Cook Airlines lagerstyrning och utifrån det har föl-jande två frågeställningar tagits fram: (1) vilka lagerstyrningsmetoder som används idag och (2) hur lagerstyrningen kan effektiviseras med hjälp av ett MRP-system. Vi har fördjupat oss i olika lagerstyrningsmetoder, så som beställningspunkten, ekonomisk orderkvantitet och ABC-klassificering, som förklarar olika sätt att styra ett lager. Vi har även presenterat en teori om MRP-system, vilket innebär att företag kan minimera lagernivån och minska risken för över-skott av lager. Adderas koncepten LEAN och JIT kan fler fördelar erhållas. Uppsatsens empi-riska material bygger på intervjuer, observationer och textdokument. I slutsatsen kom vi fram till att Thomas Cook Airlines delvis arbetar med lagerstyrning. De vill säkerställa en hög servicenivå, men det medför ett högt lagervärde på lagret, vilket inte är önskvärt. Företaget har en upprättad ABC-klassificering, men denna används inte i tillräcklig utsträckning. Vi presenterar två MRP-system, RELEX och AFP, som ger en rad fördelar så som orderförslag samt att användaren inte behöver klistra in rapporter i Excel, som är det nu-varande arbetssättet. Thomas Cook Airlines lagerstyrning kan bli mer effektiv med ett MRP-system. Utifrån koncepten om LEAN och JIT anser vi även att en leverantörs- och artikelre-ducering kan vara lämplig. / Right product, in the right place and at the right time are important aspects of a producing company. There are different inventory control methods a company can use to ensure these aspects which this paper will discuss. The purpose of this essay is to describe Thomas Cook Airlines inventory control, and from this, the following two problem definitions have been developed: (1) which inventory control methods are used today and (2) how inventory control can be streamlined using an MRP sys-tem. We have deepened ourselves in different inventory control methods, such as the ordering point, economic order quantity, and ABC classification, explaining different ways how to control inventory. We have also presented a theory about MRP systems which indicates that companies with MRP systems can minimize their inventory level and reduce the risk of inven-tory overflow. If the concept’s LEAN and JIT are to be added to the companies’ strategies more advantages will obtain. In this paper, our empirical material is based on interviews, ob-servations and text documents. In our conclusion, we found that Thomas Cook Airlines partly works with inventory control. The company wants to maintain a high level of service, but it implies a high inventory value which is not desirable. The company has an established ABC classification, but it is not used to a sufficient extent. We present two MRP systems, RELEX and AFP, who gives a number of benefits such as suggested orders. Also, they no longer need to generate different reports from different systems to Excel. Thomas Cook Airlines inventory control can be more effec-tive with an MRP system. Based on the concepts of LEAN and JIT, we also consider that a supplier and article reduction may be appropriate.

F1FO ATP synthase is a membrane bound enzyme capable of synthesizing and hydrolyzing ATP. Lately, α-helical cationic peptides such as melittin and melittin related peptide (MRP) were shown to inhibit E. coli ATP synthase. The proposed but unconfirmed site of inhibition is βDELSEED-motif formed by the residues 380-386, located at the interface of α/β subunit of ATP synthase. This project was a mutagenic analysis of βDELSEED-motif residues to understand the binding mechanism and mode of action of peptide inhibitors. The study addressed 2 main questions: Are the antibacterial/anticancer effects of these peptides related to their inhibitory action on ATP synthase through interaction with the βDELSEED-motif? If so, which amino acid residues play critical role in peptide binding? The findings demonstrated that the βDELSEED-motif is the binding site of the above peptides on ATP synthase and Glutamate residues are more important in peptide binding than the Aspartate residues.

This thesis develops and presents a new remanufacturing MRP time-phased scheduling algorithm utilizing a critical path concept, as in the project management field, for incorporation into remanufacturing production planning MRP calculations. The algorithm automates the remanufacturing lead time allowance calculation for child subassemblies and component parts in the form of Stack Time, and as such creates a linkage between the parent remanufacturing routing operation to which a remanufactured subassembly or component part is allocated for further processing, and the parent routing operation from which it is disassembled. This new MRP scheduling algorithm is optimal for calculating the total planned production time of remanufacturing production routings, and is appropriate for even large, complex, multilevel BOM structures.

More than one billion vehicle tires reach the end of their useful service life annually. Less than a quarter of rubber waste is reused or recycled in some way. Interest has grown in working to discover means by which to incorporate rubber tire waste into construction materials. This study sought to delve into the use of micronized rubber powder (MRP) as an acoustic agent within particleboard and concrete. In addition, work was conducted to characterize the effect that MRP has on the strength and flexural properties of concrete. Furthermore, research sought to provide insight into how pine biomass, a forest products industry waste, would interact with MRP in concrete as it relates to strength and acoustic properties. As expected, particleboard that contained MRP resulted in lower strength but higher flexibility. Acoustic testing revealed that there was minimal sound absorption improvement at some frequencies and less absorption at low and high frequencies. Sound transmission loss was slightly improved by the addition of MRP to the particleboard. Adding pine biomass and MRP to concrete yielded much lower compressive strength as compared to plain concrete. Visual inspection of the sound absorption coefficient curves over the full range of test frequencies identified limited, if any, advantage for the addition of MRP or biomass. Some ranges of frequencies offered minimal improvement. There appeared to be no appreciable sound absorption advantage to adding MRP, pine biomass, or the combination of the two into concrete mix proportions. Modulus of rigidity was decreased as compared to plain concrete when MRP, pine biomass, or a combination of both were incorporated into the concrete mixture as volume replacement for aggregate. Visual observation revealed that flexural failure for the MRP or pine beams were less sudden and less catastrophic than the plain concrete samples. Modulus of elasticity was decreased as compared to plain concrete when MRP, pine biomass, or a combination of both were incorporated into the concrete mixture as volume replacement for aggregate. The more flexible and ductile concrete produced with MRP and biomass provides a combination of properties that serve to lessen the propagation of cracks throughout the specimen.

Within the last 30 years, Manufacturing Resource Planning (MRP-type) computer systems have quickly evolved from basic materials requirement planning software to today's enterprise resource planning (ERP) integrated software packages that reside on client/server computer architecture. However, given the magnitude of influence these computer systems encompass, very little research has been conducted to monitor and improve how companies are actually using these MRP, advanced MRP and ERP computer systems. In practical terms, where is the typical manufacturing organization today in terms of MRP systems development? To what extent is software being applied for use in enterprise integration? A survey study of manufacturing companies in Virginia and Tennessee was conducted to evaluate the current use and performance of computer systems to support manufacturing applications. This study explores the reasons why organizations chose to use these systems, the problems and benefits derived from the MRP/ERP systems, and the characteristics of the types of companies that have benefited from the use of MRP-type systems. The survey participants evaluated the performance of their manufacturing or enterprise planning systems on the basis of data accuracy, customer satisfaction, user satisfaction, systems effectiveness, convenience, information relevance, and software reliability. Furthermore, success factors associated with organizational performance were tested and evaluated. The correlation between perceived performance was tested against the influence of upper management support, the level of emphasis on training, sources of technical expertise, and organizational experience with MRP-type systems. / Master of Science

The thesis deals with production planning. It contains theoretical description of methods used for production planning and optimizing. Thesis describes bottleneck problems in production. It offers overview of ways to identify and analyze bottleneck influence to manufacturing process efficiency. Thesis proposes ways to eliminate bottlenecks using various algorithm types. It applies theoretical knowledges from optimization and graph theory to program creation that is focused on order delay and readjustment time minimizing. The program implements genetic algorithm.

Tendency of this diploma thesis is to find cost of economies through the device of lean production. On the basis of more than fourmonth monitoring and classification was specificated the problem, which is solved by implementation devices of lean production. Thanks these devices would be cut the bussines costs and salary and helps to do One piece flow too.