Syftet med studien var att undersöka hur förekomsten av sammanbrott kan minskas. Detta utifrån familjehemsföräldrars upplevelser av stöd och behov av stöd från Humana, samt familjehemsföräldrarnas upplevelser av relationen mellan familjehem och det placerade barnet. Kvalitativa semistrukturerade intervjuer genomfördes digitalt med fyra konsulentstödda familjehem. Respondenterna upplevde att stödet var tillfredsställande, men att de saknade fler grupphandledningar. Studien visade att familjehemsföräldrarna upplevde att Humanas stöd vid konflikter mellan familjehemmet och det placerade barnet minskade risken för sammanbrott, alternativt fördröjde ett sammanbrott i de fall det var oundvikligt. Vi hade fått en mer heltäckande bild om vi tog hänsyn till det placerade barnets eget perspektiv men av etiska skäl exkluderades barnens perspektiv från studien. En lämplig matchning mellan familjehem och barn innan placeringen visade sig kunna motverka sammanbrott då det ledde till en bättre relation mellan placerat barn och familjehemsföräldrar. / The aim of this study was to examine how the occurrence of placement breakdowns can be reduced. This through foster parents’ experiences of support and need of support from Humana, together with the foster parents’ experiences of the relationship between themselves and the foster child. Qualitative semi-structured interviews took place digitally with four consultancy-supported foster parents. The respondents found the support satisfying, but wanted more group tutoring. The study showed that the foster parents experienced that support from Humana in conflicts between them and the foster child reduced the risk of a breakdown, or delayed the breakdown in those cases it could not be avoided. Taking the foster childrens’ opinions into account would have given a bigger picture, but their point of view was excluded due to ethical reasons. A suitable match between the foster parents and the child led to a better relationship and therefore resulted in preventing breakdowns.

Being able to predict the outcome of a game is useful in many aspects. Such as,to aid designers in the process of understanding how the game is played by theplayers, as well as how to be able to balance the elements within the game aretwo of those aspects. If one could predict the outcome of games with certaintythe design process could possibly be evolved into more of an experiment basedapproach where one can observe cause and effect to some degree. It has previouslybeen shown that it is possible to predict outcomes of games to varying degrees ofsuccess. However, there is a lack of research which compares and evaluates severaldifferent models on the same domain with common aims. To narrow this identifiedgap an experiment is conducted to compare and analyze seven different classifierswithin the same domain. The classifiers are then ranked on accuracy against eachother with help of appropriate statistical methods. The classifiers compete onthe task of predicting which team will win or lose in a match of the game BloodBowl 2. For nuance three different datasets are made for the models to be trainedon. While the results vary between the models of the various datasets the general consensus has an identifiable pattern of rejections. The results also indicatea strong accuracy for Support Vector Machine and Logistic Regression across allthe datasets.

Helmut Lachenmann’s theory of perception highlights musical moments that step out of a coherent stream of self-contained musical logic and challenges established categories of musical experience. The penultimate scene (No. 23: Shō) of Lachenmann’s »opera« The Little Match Girl (1991-96/2001) and the airy chords in the final section of his large ensemble work Concertini (2004/2005) arguably represent such moments of fundamental musical alterity in the composer’s recent output that are characterised by a specific auratic emphasis. Closer examination, however, suggests that these sections are also multiply mediated by self-references with the larger musical structure of these extensive works. This article provides a loosely connected series of discussions on how a balance between alterity and self-referentiality is achieved in these two examples. The discussions acknowledge the distinction between »extra-opus« and »intra-opus« references derived from cognitive science and music theory and focus on pitch organisation, sectional time structure, narrativity and interculturality. The Japanese mouth organ shō that figures prominently in the opera scene and, according to the composer, provides the »scale« for the concluding sounds in Concertini, without doubt symbolizes a moment of fundamental alterity due to its unique timbre, its unalienated sound and a basic articulation derived from the Japanese court music repertoire tōgaku. A detailed analysis of fingerings and pitch organisation, however, reveals a »double-coding« of Lachenmann’s material: on the »extra-opus« realm it refers to or »deconstructs« both Japanese and European musical conventions, on the »intra-opus« realm it connects to the framing scenes of the opera and forms part of a large-scale »cadence sound« that reconsiders the complete spectrum between pitched and unpitched sounds within the three closing scenes. The »utopian« shō-chords played by wind instruments in the final section of Concertini, in contrast, create a more fragmentary type of »cadence sound« due to their short durations, but nevertheless exert a »magnetic« attraction that temporarily assembles the heterogeneous »sound families« of the piece into transient sonic entities. A detailed overview of the sectional time structures reveals that in both cases the music follows a rather rigid sequence of proportions derived from Fibonacci series and the golden section, and includes several quasi symmetrical time layers. In both examples this time structure supports pivotal formal processes: in the shō-scene from the Little Match Girl it suggests a shift from the predominance of shō-sounds to their increasingly independent orchestral »resonances«, in Concertini the symmetrical position of the »shō-chords« within the final section emphasizes their cadential function and »magnetic« effect. The concluding discussions on narrativity and interculturality suggest that – partly in contrast to the preceding arguments of this essay – the analysed sections tend to subvert the conventional closure concept of a »cadence« and rather create open endings. The self-referential elements in the Little Match Girl’s construction of the shō and its inclusion in a re-invented type of »celestial mechanics« discloses non-essentialist, polyvalent strata of musical meaning that match Lachenmann’s concept of nonconventional musical narrativity and non-exploitative musical interculturality (a concept that he has critically discussed at length in a recent article). This is especially cogent when his shō-music is compared to other recent works for the Japanese mouth organ that recontextualize its sounds by »demythologization« in a much more obvious, arguably didactic manner. Finally, Lachenmann’s key idea of »liberated perception« is associated with this discussion on interculturality and traced back to moments in Keiji Nishitani’s philosophy – leaving this article open to further research.

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Animals learn from past experience to guide future behavior and improve survival. This ability relies in part on specific episodic memories of past events encoded by neuronal activity and stored by updated connectivity between neurons. The unique architecture and activity of the hippocampus and related cortical regions are crucial for supporting these episodic memories. Hippocampal models propose the need for a pattern separation function to disambiguate similar memories and a pattern completion function to recall the full breadth of an experience from a partial cue. Past work suggests that neuronal activity in the dentate gyrus (DG) of hippocampus contributes to memory-guided navigation and plays a role in pattern separation. We tested the role of specific DG neuronal ensembles (i.e. engrams) in supporting the pattern separation function and altering downstream neural activity and, ultimately, behavior. To that end, we used an activity-dependent labeling paradigm to identify and manipulate engram ensembles during navigational and contextual fear conditioning (CFC) tasks. The results of our first experiment revealed that the DG partially disambiguates specific maze trajectories while still exhibiting greater overlap than chance levels. These findings suggest that the DG contributes to memory-guided navigation by both pattern separation and completion. Our second experiment manipulated nonspecific memory-related DG populations to assess the functional role of these cells in task generalization across contexts and ongoing spatial working memory. Optogenetic activation of these ensembles disrupted performance accuracy and exhibited a time-dependent impairment effect suggesting a role of the DG in task generalization between contexts. The final experiments investigated the physiological ramifications of artificial memory ensemble reactivation during ongoing navigation behavior. We recorded local field potential (LFP) and single unit responses in mouse DG and CA1 during artificial reactivation of a DG-mediated CFC memory engram. Stimulation of the DG entrained LFP and individual cell spiking in a subpopulation of CA1 pyramidal cells. Their spatial information was disrupted by stimulation despite stable navigational representation before and after the manipulation. Further, the presence of stimulation could be reliably decoded by the firing rate of the network, suggesting that engram reactivation forced the CA1 to adopt a repeatable state, perhaps to support behavioral expression of memories. In summary, my dissertation work presents empirical and theoretical evidence for the role of the dentate gyrus as a single node of an extended separation/completion circuit distributed anatomically and temporally as a neural mechanism supporting episodic memory.

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The aim of this study was to explore how match-related statistics contribute to winning association football matches. This is relevant for stakeholders in the football industry to facilitate the understanding of what factors contribute to winning matches and can thus be of use when formulating match tactics. A model was constructed through the use of binary logistic regression, where winning/not winning was used as the response variable and standardized match-related statistics were used as predictor variables. Using the acquired coefficients, it was concluded that, among other variables, the home advantage and the ability of a team to finish on target has a strong correlation with winninggames. Further, the study explores the impact of a team’s ability to win football games on the financial landscape of the modern football world. The results show that some of the examined statistics are well correlated to winning a match, but that the tactical useability of these insights is low. / Syftet med denna studie var att utforska hur matchrelaterad statistik bidrar till att vinna fotbollsmatcher. Detta är relevant för aktörer inom fotbollsbranchen för att underlätta försåelsen av vilka matchrelaterade faktorer som bidrar till vinst och kan således användas för att forma matchtaktik. En modell konstruerades genom binär logistisk regression, där att vinna/att inte vinna användes som responsvariabel och standardiserad matchrelaterad statistik användes som prediktorvariabel. Genom att använda koefficienterna tillhörande modellen,kan man fastslå att bland annat hemmalagsfördel samt ett lags förmåga att träffa mål korrelerar starkt med att vinna matcher. Dessutom utforskar studien påverkan av ett lags förmåga att vinna fotbollsmatcher på det finansiella landskapet tillhörande den moderna fotbollen. Resultaten visar att vissa av de studerade variablerna korrelerar starkt med att vinna fotbollsmatcher, men attmöjligheterna att använda dessa insikter till att forma taktik är begränsade.

<p>AMR as a cause of graft rejection has been long recognized and the presence of pre formed antibodies against donor HLA is a risk factor for increased graft rejection. FlowXM is the current clinical gold standard for detecting harmful DSA in the recipients and a positive FlowXM is considered a strong contraindication to transplantation. However, newer techniques such as SAB provide with a highly sensitive and specific method for DSA detection that is unattainable by FlowXM. But due to the intrinsic limitations associated with SAB assays, the clinical relevance of DSA detected on SAB has been highly disputable. Therefore, the overall aim of this study was to investigate the utility of SAB in predicting harmful DSA levels, by establishing a fluorescence range on SAB that correlated to positive FlowXM. This was done by retrospectively testing the highest serum dilutions on FlowPRA SAB that produced positive B or T cell FlowXM from 15 variably sensitized patients. Thus, a very narrow MFI range on SAB was established, for B and T cells separately, that correlated to positive FlowXM. On B cells this correlate ranged from 2780-7772 MFI (Mean MFI =5641), whereas T cell range was 1089-6731 (Mean MFI= 3226). In order to test these ranges for prediction of positive FlowXM, B and T cell FlowXM tests were carried out using various serum/cell combinations. DSA MFI of >3000 on SAB resulted in a significantly higher T cell positive FlowXM (p</p> / Master of Science (MSc)

Background: The rapid growth of social media has transformed the influencer marketinglandscape, making Gen Z overwhelmed with digital content and more discerning aboutauthenticity and brand alignment in influencer partnerships. As brands are increasinglyusing fashion influencers as a primary marketing tool due to their substantial impact onconsumer decisions, understanding influencer-brand fit is crucial, highlighting the need forfurther exploration of the consequences of a poor fit. Purpose: The purpose of this exploratory study is to gain a deeper understanding of howfemale Gen Z evaluates factors influencing their perception of influencer-brand fit withinthe fashion industry on Instagram, specifically exploring the consequences of a poor fit. Method: Using a qualitative research design within an interpretivist paradigm andinductive approach, empirical data was gathered through semi-structured focus groups andindividual interviews with female Gen Z participants, selected by judgment sampling. Thedata was then analysed using thematic analysis to derive meaningful insights. Conclusion: This study reveals the multifaceted dynamics of influencer-brand fit and itsimpact on female Gen Z's perceived credibility of both fashion influencers and brands.Findings reveal that the factors influencer characteristics, parasocial interactions,collaborative structure, external influence, and influencer-brand image play a pivotal rolein influencing female Gen Z's perception of an influencer-brand fit. Furthermore, the studyhighlights the outcomes of an influencer-brand fit, underscoring that a strong fit increasescredibility and loyalty while a poor fit decreases consumer trust, engagement andcredibility. This study highlights the evolving nature of consumer responses and theimportance of understanding the nuanced preferences of this demographic, underscoringthe need for brands to strategically select influencers whose image and values align closelywith their own.

Syfte: Syftet med uppsatsen är att undersöka vad det finns för finansiellt syfte med att köpa namnrättigheterna för en arena där det i främsta fall bedrivs idrottsrelaterade evenemang. Delsyftet är att undersöka hur företagets aktiekurs påverkas vid tillkännagivandet av att de blir arenasponsor samt att se huruvida arenasponsorns aktiekurs påverkas efter att ett idrottsevenemang ägt rum. Metod: Undersökningen är en flerfallsstudie av fem företag där en metodtriangulering med en kombination av kvalitativ och kvantitativ metod används för att på så sätt ge en rättvis bild av fenomenet. Uppsatsen utgår från ett positivistiskt vetenskapligt förhållningssätt och ett deduktivt angreppssätt. Den kvalitativa delen av uppsatsen består av primärdata i form av intervjuer med personer från ansvariga positioner på företagen. Den kvantitativa delen består av en eventstudie-metodologi där den insamlade datan användes för att mäta om en avvikande avkastning (AR) uppstod i samband med tillkännagivelsen av namnrättighetsaffären samt en genomsnittlig avvikande avkastning (AAR) vid idrottsevenemangen. Utöver detta undersöktes även om specifika matchutfall påverkade företagens aktiekurs. Eventperioden för idrottsevenemangen sattes till dagen efter evenemanget medan eventperioden för tillkännagivelsen sattes till 75 dagar, 25 dagar innan och 50 dagar efter nyheten. Uppsatsens estimeringsperiod omfattade i båda fall 70 dagar. Resultat: Vid tillkännagivandet av arenarättighetsaffären uppvisar resultatet mellan en positiv AR på 2,48 procent till en negativ AR på 1,44 procent för de sex rättighetsaffärerna. Vid matchutfallen uppvisar resultatet allt från en positiv AAR på 0,26 procent till en negativ AR på -0,06 procent. Slutsats: Arenasponsringens stora finansiella vinning ges genom ett starkt varumärkeskapande vilket på sikt leder till ökade finansiella fördelar för företaget med namnrättigheterna av arenan. Finansiellt påverkades inte företagets aktiekurs av varken matchutfall eller tillkännagivandet av arenasponsringsnyheten. / Purpose: The aim of the thesis is to see what the financial purpose is for buying the naming rights of an arena where the main activity is sporting events. The subsidiary aim is to investigate if the company's share price is affected by the announcement that they became arena sponsors and to see whether the stadium sponsor's share price is affected after a sporting event has taken place. Methodology: The survey is one multi-case study of five companies, which are based on both a quantitative and a qualitative approach. The paper was based on a positivistic scientific approach and deductive approaches. The qualitative part of the thesis consists of primary data in the form of interviews with individuals holding responsible positions in the companies. The quantitative part consisted of an eventstudy, where the collected data is used to measure if an abnormal return (AR) has arisen in connection with the announcement of the name rights deal and an average abnormal return (AAR) in connections with the sporting events. Event period for sporting events is added to the day after the event while the event period for the announcement is added to 75 days, 25 days before and 50 days after the news. The surveys estimationperiod was comprised to 70 days. Results: At the announcement of the arena namingrights deal presented results from a positive AR of 2.48 percent to a negative AR of 1.44 percent. During the match, the outcome showed the results of a positive AAR of 0.26 percent to a negative AR of -0.06 percent. Conclusions: The big financial benefit of buying the naming rights of an arena is the strong brandbuilding which ultimately leads to increased financial benefits for the sponsoring company. The company's share price is not affected  by either match outcomes or the announcement of the sponsorship deal.