Made available in DSpace on 2016-06-02T19:32:00Z (GMT). No. of bitstreams: 1 4125.pdf: 2555973 bytes, checksum: 6e384fbcd72f2a660b5bc6c0cf0c8739 (MD5) Previous issue date: 2012-02-10 / Financiadora de Estudos e Projetos / The studies related to the interactions among populations in the aquatic communities are essential for providing relevant information for the understanding of energy and matter pathways in the ecosystems and subsidize to the formulation of trophic web models.The occurrence of flexible diets is a marked feature of many species in the ichthyofauna of Tropical Rivers, where the same species can alternate the exploitation among food items according to the changes in the relative availability of food resources induced by temporal spatial and or ontogenetic changes. In this context, this study aimed to analyze the trophic interactions existing between the species Geophagus brasiliensis (Quoy & Gaimard, 1824) (Osteichthyes, Cichlidae), and benthic macroinvertebrate community in three reservoirs (Monjolinho Reservoir, Fazzari Reservoir, Broa Reservoir) in order to know its feeding mode, whether there is food selectivity or preference and which would be the most suitable trophic category for the species. Benthic macroinvertebrate communities in sediments sampled simultaneously to G. brasiliensis population were analysed and experiments were carried out in order to know the feeding mode of the species. Biometric measurements for ecomorphological analyses and analysis of stomach contents of the fishes were performed and based on qualitative and quantitative analyses of the macroinvertebrates consumed and their availability in the environment the values for the selectivity index of Paloheimo were calculated for the reservoirs sampled. The results showed that benthic macroinvertebrates are often used as food resource by the populations of G. brasiliensis with great participation in its diet, allowing us to characterize this species as a benthivore. Also, it was observed that G. brasiliensis has food preference for Chironomidae larvae. / Os estudos sobre as interações tróficas entre populações nas comunidades aquáticas são fundamentais por fornecerem informações relevantes para o entendimento dos caminhos do fluxo de energia e de matéria nos ecossistemas e subsidiar a formulação de modelos sobre teias tróficas. A ocorrência de dietas flexíveis é uma característica marcante de muitas espécies da ictiofauna fluvial tropical, onde uma mesma espécie pode alternar a exploração de itens alimentares em função das variações na disponibilidade relativa do recurso alimentar motivadas por alterações temporais, espaciais e ou ontogênicas. Neste contexto, este trabalho teve por objetivo analisar as interações tróficas existentes entre a espécie Geophagus brasiliensis (Quoy & Gaimard, 1824) (Osteichthyes, Cichlidae) e a comunidade de macroinvertebrados bentônicos em três represas (Represa do Monjolinho, Represa do Fazzari e Represa do Broa), a fim de avaliar seu modo de alimentação, verificar se existe seletividade ou preferência alimentar e em que categoria trófica esta espécie melhor se enquadra. Foi analisada a composição dos macroinvertebrados bentônicos em sedimentos coletados simultaneamente as amostragens das populações de G. brasiliensis, e foram realizados experimentos em laboratório para verificar o modo como a espécie se alimenta. Medidas biométricas para caracterização ecomorfológica e análises do conteúdo estomacal dos peixes foram feitas e com base nas análises qualitativas e quantitativas dos macroinvertebrados consumidos e sua disponibilidade no ambiente foram calculados os valores do índice de seletividade de Paloheimo para os reservatórios amostrados. Os resultados mostraram que os macroinvertebrados bentônicos são frequentemente utilizados como recurso alimentar pelas populações de G. brasiliensis, tendo grande participação em sua dieta, o que poderia caracterizá-la como uma espécie bentívora. Observou-se também que G. brasiliensis tem preferência alimentar por larvas de Chironomidae.

Made available in DSpace on 2014-12-17T15:46:29Z (GMT). No. of bitstreams: 1 DeriscleiaRR.pdf: 395162 bytes, checksum: f30ae84fd662fbd205a7c312e9e1bb36 (MD5) Previous issue date: 2006-08-22 / This research comprises a study about the social assessment performed by the Social Worker in the review process of the Benefit of Continued Installment. The Benefit of Continued Installment was implemented in 1996 and guarantees a minimum salary to the deficiency person and to an elder with sixty five years or more and that proves not to have ways to support neither himself/herself nor his/her own family. It is a demand to include in the BPC that the maximum income of a family does not exceed ? of minimum salary and that every two years this benefit to be revised to evaluate its continuity based in its original conditions. This study was carried out in the municipality of Natal/RN, with thirteen social workers, being the collection of data performed through interviews and social assessments of the users that count with the benefit. The results show that the users selected by the criterion of the income, present a profile of poverty and deprivations demonstrated through several situations survived in its daily life, indicative of vulnerability. It was demonstrated that the Social workers has relative autonomy in the evaluations along with the users and that it denotes the necessity of inclusion. However, by following the imposed criteria, it corroborates with the logic of exclusion. So, it is identified in the Municipality of Natal/RN, following the orientation given the politics of social work at national level, the implementation of revision of the BPC, for the social workers, from rigorous processes of selection and exclusions / Esta pesquisa compreende um estudo sobre a avalia??o social realizada pelo Assistente Social no processo de revis?o do Benef?cio de Presta??o Continuada. O Benef?cio de Presta??o Continuada come?ou a ser implementado em 1996 e garante um sal?rio m?nimo ? pessoa portadora de defici?ncia e ao idoso com sessenta e cinco anos ou mais e que comprove n?o possuir meios de prover a pr?pria manuten??o e nem de t?-la provida por sua fam?lia. ? exig?ncia para inclus?o no BPC que a renda m?xima da fam?lia n?o ultrapasse ? de sal?rio m?nimo per capita e a cada dois anos o benef?cio ? revisto para avalia??o da continuidade das condi??es que lhe deram origem. A pesquisa foi realizada no munic?pio de Natal/RN, com treze assistentes sociais, sendo a coleta de dados efetuada atrav?s de entrevistas e das avalia??es sociais dos usu?rios indicados ao corte do benef?cio. Os resultados revelam que os usu?rios selecionados pelo crit?rio da renda apresentam um perfil de pobreza e priva??es, demonstradas atrav?s de diversas situa??es vivenciadas em seu cotidiano, indicativas de vulnerabilidade. Demonstrou que o assistente Social possui relativa autonomia nas avalia??es junto aos usu?rios e que denota a busca pela inclus?o, mas, ao seguir os crit?rios de seletividade impostos, corrobora com a l?gica de exclus?o. Assim, identifica-se no munic?pio de Natal/RN, seguindo a orienta??o dada ? pol?tica de assist?ncia social no ?mbito nacional, a implementa??o da revis?o do BPC, pelos assistentes sociais, a partir de processos de sele??o rigorosos e excludentes

Orientador: Javier Sanz Contreras / Resumo: Neste trabalho, apresenta-se uma nova proposta de metodologia para alocar, determinar e es-pecificar os tipos de dispositivos de controle e proteção em redes de distribuição com geração distribuída (GD). Esta metodologia é baseada em técnicas de otimização multiobjetivo para efetuar a alocação otimizada, coordenada e seletiva destes dispositivos. O modelo é composto por duas funções objetivo que consideram aspectos econômicos e da confiabilidade da rede, e um conjunto de restrições composto por restrições físicas, operacionais e um subconjunto de restrições baseadas em regras práticas das empresas do setor de distribuição e previstas em normas técnicas nacionais e internacionais que estabelecem a especificação, coordenação e seletividade dos dispositivos de controle e proteção instalados na rede. No modelo considera-se a possibilidade de transferência de carga entre alimentadores vizinhos e a operação ilhada da GD. Dessa forma, obtém-se um modelo genérico de programação não linear inteira mista (PNLIM) cujo diferencial com relação a outros modelos matemáticos da literatura é propor que no mesmo processo de otimização seja realizada a alocação otimizada dos dispositivos de controle e proteção na rede juntamente com a coordenação do sistema de proteção. A eficiên-cia do modelo matemático é comprovada comparando-se os resultados obtidos entre dois tes-tes com o auxílio do algoritmo genético (AG) mono-objetivo que considera a ponderação dos objetivos, enquanto que para a solução ... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: This paper, presents a new methodology for placing, selecting and specifying the control and the protective devices system of distribution networks with distributed generation (DG). This methodology is based on multiobjective optimization techniques to perform the optimized, coordinated and selective allocation of the control and protective devices. The proposed mathematical model consists of two objective functions that consider economic factors and network continuity indexes. Physical and operational constraints are taken into account, with an emphasis on the set of constraints based on practical rules of distribution utilities defined in international technical standards, which require the specification, coordination, and selectivity of protective devices installed in the network. The possibility of load transfer from neighboring feeders and the islanded DG operation are also considered in the model. In this way, we obtain a generic model of mixed-integer nonlinear programming (MINLP) whose differential in relation to other mathematical models of the literature is to propose, in the same optimization process, the optimized allocation of the control and protective devices in the network along with the coordination of the protection system. The efficiency of the mathematical model is proven by comparing the results obtained in two tests with the aid of the genetic algorithm (GA) while for the solution of the multiobjective MINLP model the NSGA-II multiobjective genetic algor... (Complete abstract click electronic access below) / Doutor

Les caractéristiques structurelles et fonctionnelles du zooplancton du bassin versant de l'Escaut ont été étudiées en relation avec les conditions environnementales présentées dans les cours d'eau. L'Escaut est un fleuve long de plus de 350km répartis entre la France, la Belgique et les Pays-Bas. Son bassin versant draine un territoire soumis à de nombreuses pressions d'origine anthropique industrielle, agricole et domestique. Par conséquent, d'après l'évaluation de la Directive Cadre sur l'Eau, l'état écologique des cours d'eau est jugé plutôt insatisfaisant. Les précédentes études sur le zooplancton de l'Escaut ayant porté principalement sur les tronçons estuariens du fleuve, les communautés zooplanctoniques des cours d'eau de l'amont du bassin versant, dans la zone transfrontalière entre la France et la Belgique étaient jusqu'alors non documentées à notre connaissance. De la source à l'embouchure de l'Escaut, 4 grandes zones fonctionnelles ont pu être identifiées présentant différentes conditions d'habitat pour le zooplancton, définies principalement par le gradient de salinité et l'influence de la marée. A l'échelle de la partie non estuarienne du bassin versant, la variabilité spatiale et temporelle du zooplancton a été explorée, en relation avec les conditions environnementales. La distribution du zooplancton a montré une forte hétérogénéité, induisant une faible prédictibilité dans au regard de l'état écologique (DCE), des conditions environnementales et des profils de contamination des sites (en considérant une gamme de polluants organiques persistants et métaux traces caractéristiques de la zone d'étude). En revanche, un rôle trophique important a pu être mis en évidence, avec une sélectivité trophique de la fraction zooplanctonique 50 -250 µm envers les groupes algaux, en particulier les Chlorophytes, et un broutage suggéré sur les cyanobactéries. / Structural and functional characteristics of the Scheldt basin zooplankton have been studied in relation with environmental conditions presented in watercourses. The Scheldt runs for 350 km from Northern France to the Netherlands, crossing Belgium. Its basin drains an area subject to multiple pollutions originating from industrial, agricultural and domestic activities. As a consequence, ecological states of watercourses are unsatisfactory according to the Water Framework Directive (WFD) evaluation. So far, studies on Scheldt zooplankton have focused on estuarine reaches, and the upstream basin's communities were scarcely documented. From source to mouth of the Scheldt, 4 functional zones have been identified presenting different habitat conditions for zooplankton, defined mainly by salinity gradient and tidal influence. At the scale of the non-tidal watershed, spatial and temporal variability of zooplankton communities have been explored, in relation with environmental conditions. Zooplankton distribution showed a strong heterogeneity, inducing little predictability concerning ecological status (WFD), environmental conditions, and contamination patterns of sites (considering a set of persistent organic pollutants and trace metals characteristics of the study area). However, an important trophic role has been highlighted. The zooplankton community between 50-250 µm showed a selective feeding on some algal groups, particularly on chlorophytes, and and the results suggest a grazing activity on cyanobacteria.

L’identification des muscles responsables des dystonies focales est un prérequis à l’instauration des traitements par toxine botulique et exercices correcteurs. A partir de deux dystonies apparemment dissemblables: la crampe de l’écrivain et la dystonie cervicale, nous avons montré que la réponse aux traitements est tributaire de la distribution des muscles impliqués. L’enregistrement des mouvements du segment tête-cou dans la dystonie cervicale , au moyen de capteurs inertiels 3-D, a montré qu’au mouvement volontaire de la tête, dans un plan, s’associent des mouvements non physiologiques dans les deux autres plans. Pour déterminer les actions musculaires en cause, nous avons réalisé une modélisation numérique du segment tête-cou permettant d’associer le muscle responsable aux déformations. Par ailleurs, sachant l’importance des phénomènes sensitifs dans le contrôle du mouvement, nous avons, au cours de tâches d’ajustement de la force musculaire, montré que ce contrôle de la force est perturbé dans chacune des deux dystonies focales étudiées.Nos résultats devraient avoir une implication dans les traitements symptomatiques de ces dystonies. / The identification of the muscles responsible for focal dystonia is a prerequisite to the introduction of botulinum toxin treatment and tailored exercises. From two apparently dissimilar dystonia: writer's cramp and cervical dystonia, we showed that the response to the treatments depends on the distribution of the muscles involved. Recording the movement of the head-neck segment in cervical dystonia, using 3-D inertial sensors, showed that voluntary head movement in a plane is associated with non-physiological movement in the two other planes. To determine the muscular actions involved, we performed a digital modeling of the head-neck segment which allows us to link the responsible muscle with abnormal postures.Therefore, knowing the importance of sensory phenomena in the control of movement, we have, during tasks of muscular force adjustment, demonstrated that force control is altered in both studied dystonia.Our results should have implications in the symptomatic treatment of these dystonias.

Les réseaux multi-terminaux à courant continu sont une solution efficace pour intégrer l’énergie électrique produite en grande quantité par de grands parcs éoliens offshore. Bien que le recours à la technologie HVDC soit maitrisé pour des applications point-à-point, des verrous technologiques sont encore à lever pour permettre une exploitation sûre d’un réseau à courant continu. La protection est le principal domaine technique pour lequel des progrès sont encore attendu. Des stratégies de protection fiables et assurant le meilleur ratio technico-économique sont à l’étude. Ces travaux de thèse ont pour objectif la mise en œuvre d’une philosophie de protection à sélectivité totale, identique à celle utilisée dans les réseaux de transport traditionnels. Cette étude considère l’utilisation de liaison par câbles uniquement, de convertisseurs VSC-MMC composées de sous-modules en demi-pont et de disjoncteurs hybrides à courant continu. Une association de deux algorithmes de détection de défaut a été proposée. Une étude du temps disponible pour l’élimination du défaut a été menée. Enfin, des simulations numériques avec le logiciel EMTP ont permis d’évaluer la fiabilité de la stratégie de protection. / In a near future, multi-terminal High Voltage Direct Current grids (MT-HVDC grids) appear to be a suitable solution for the integration of power electricity produced by remote offshore windfarms into the AC transmission system. Though the recourse to HVDC point-to-point links is well-known, challenges still remain for a safe operation of HVDC grids. Protection is the main technical field still under study and reliable protection strategies ensuring the best technological and economic ratio are investigated. This thesis focused on a full selective protection philosophy similar to the one applied to AC transmission systems. The consideration of cable links, Half-Bridge VSC-MMC converters and hybrid DC circuit breakers defines the frame of the study. An association of two algorithms for the identification of faults is suggested. The time available for the fault clearing process has been investigated. Simulations performed with EMTP software have been used to evaluate the reliability of the suggested strategy.

Malgré les avancées thérapeutiques récentes, un nombre significatif de patients décèdent de leur cancer suite au développement de métastases. Les molécules conventionnelles de chimiothérapie ont un rôle pivot à ce stade, mais leur efficacité qui est dépendante de la dose, est limitée par leur toxicité aux tissus non tumoraux, par manque de spécificité. L’enjeu est de développer des approches spécifiques qui augmentent la toxicité de ces molécules pour les tumeurs sans affecter les autres tissus. L’acide docosahexaènoïque (DHA) est capable d’augmenter la sensibilité des tumeurs à la chimiothérapie de façon spécifique sans sensibiliser les tissus non tumoraux. Ce travail de thèse présente 1) une synthèse des études existantes supportant cette hypothèse, 2) l’évaluation de la faisabilité d’une supplémentation orale en DHA au cours de la chimiothérapie chez des patientes présentant un cancer du sein métastasé, 3) l’exploration des mécanismes impliqués dans la sensibilisation spécifique des tumeurs, 4) l’effet du DHA sur la perte de poids en cours de traitement, et 5) le profil d’incorporation du DHA au niveau des tumeurs et la relation avec son taux plasmatique. / Despite great therapeutic improvements, a significant proportion of patients still die from cancer, mainly because of the development of metastases. At this stage, treatments rely heavily on conventional chemotherapy, but their efficacy, which is dose-dependent, is limited by its toxicity to non-tumor tissues, as a result of their poor selectivity. The challenge is to develop approaches aimed at increasing chemotherapy cytotoxicity to tumor tissue while not affecting non-tumor tissues. Docosahexaenoic acid (DHA), a lipid of marine origin, has the potential to selectively sensitize tumor tissue to anticancer drugs without sensitizing nontumor tissues. This manuscript reports 1) a review of existing studies supporting this hypothesis, 2) an assessement of the feasiblility of supplementing breast cancer patients with DHA during an anthracycline-based chemotherapy for metastases, 3) an exploration of the mechanisms involved in the selective sensitization of tumors by DHA, 4) the effect of DHA on weight loss related to chemotherapy, and 5) the profile of DHA incorporation into tumor tissue and the relation with its level in plasma.

Les peptides sont des molécules pouvant posséder une activité biologique intéressante (antibiotique, anti-oxydante, antivirale, anti-hypertensive…). Ce sont cependant des molécules difficiles à utiliser car elles possèdent un faible temps de demi-vie in vivo et sont peu bio-disponibles. Le greffage d’un acide gras permet de les protéger et d’accroître leur potentiel d’action. Cette réaction appelée acylation peut être catalysée par des enzymes. A l’heure actuelle, peu de recherches sont faites sur l’acylation de peptides par voie enzymatique et sur la recherche de nouveaux biocatalyseurs adaptés pour cette réaction. Les objectifs de cette thèse ont été, dans un premier temps, de comprendre les mécanismes de la sélectivité d’acylation de peptides de la lipase B de Candida antarctica par une approche de modélisation moléculaire combinant docking et dynamique moléculaire, couplée à une approche expérimentale. Cette étude a permis d’identifier des interactions enzyme-substrats impliquées dans la sélectivité enzymatique et a permis de construire un modèle expliquant la régio- et chimio-sélectivité de l’acylation peptidique catalysée par cette enzyme. Dans un deuxième temps, une étude préliminaire a été menée afin d’identifier de nouvelles enzymes de type acylases présentes dans des surnageants de culture de différentes espèces de Streptomyces. Ces enzymes sont capables de catalyser des réactions d’acylation de peptides en milieux aqueux. Une méthode de semi-purification a été établie et une étude comparative a été menée sur la sélectivité d’acylation de la lipase B de C. antarctica et celle de nouvelles enzymes de type aminoacylases présentes dans un extrait protéique de surnageant de culture de Streptomyces ambofaciens. Ces nouvelles enzymes présentent une spécificité différente de celle de la lipase B de C. antarctica, permettant notamment, une acylation des acides aminés sur leur fonction amine en position α. Une caractérisation partielle des activités amino-acylase du surnageant de culture de S. ambofaciens a été réalisée. Dans une troisième et dernière partie, une comparaison des séquences génétiques a été réalisée entre treptomyces mobaraensis et S. ambofaciens afin d’identifier les gènes codant pour les acylases découvertes chez S. ambofaciens. Des mutants de S. ambofaciens délétés pour ces gènes ont été construits et la fonctionnalité des enzymes codées par ces gènes a été vérifiée ; enfin, une expression hétérologue de l’ε-lysine acylase a été initiée / Peptides exhibit various beneficial effects such as antioxidant, anti-hypertensive, neuroprotective, antiviral or antimicrobial activities. However, their use can be limited by their short half-life and their low biological availability. One solution to overcome these drawbacks is the acylation of peptides with fatty acids. This reaction called acylation can be catalyzed using enzymes. To date, very few studies focus on enzymatic acylation of peptides and on finding new enzymes catalyzing this reaction. The objectives of this work were, in a first time, to understand the selectivity mechanisms of the lipase B of Candida antarctica for peptides acylation combining experimental and molecular modeling approaches. This study highlighted enzyme/substrate interactions involved in the enzymatic selectivity and a modelexplaining the chemo- and regio-selectivity of this enzyme for peptide acylation reactions was built. In a second time, a preliminary study was carried out in order to identify new aminoacylase enzymes produced in the culture supernatant of various species of Streptomyces. These enzymes are able to catalyze acylation of peptides in aqueous media. A partial purification method was set and a comparative study was performed on the selectivity of C. antarctica lipase Band that of the new aminoacylases discovered in the culture supernatant of Streptomyces ambofaciens ATCC 23877. These enzymes presented a selectivity different from C. antarctica lipase B allowing the acylation of the N-terminal amino group of amino acids or peptides. A partial description of the aminoacylase activity of the supernatant crude extract of S. ambofaciens was performed. In a third and final part, a comparison of sequences of aminoacylases from Streptomyces mobaraensis with the genome of S.s ambofaciens ATCC 23877 was performed in order to identify genetic sequences encoding the new discovered aminoacylases from S. ambofaciens ATCC 23877. Each identified gene was deleted to correlate it with the aminoacylase activity observed in the crude extract of S. ambofaciens. Lastly, a heterologous expression of the ε-lysine acylase was initiated

L'implant cochléaire est une prothèse neurale implantée visant à restituer une sensation auditive chez des personnes souffrant de surdité neurosensorielle sévère à profonde. Si les performances en reconnaissance de la parole sont relativement bonnes dans le silence, elles chutent dramatiquement dans des environnements sonores complexes. L'une des principales limites de l'appareil vient du fait que chaque électrode stimule une large portion de la cochlée. Ainsi lorsque plusieurs électrodes sont activées les champs électriques produits interfèrent ce qui détériore la transmissions des informations sonores. Plusieurs modes de stimulation ont été proposés pour remédier à ce problème mais les améliorations en termes de reconnaissance de la parole restent limités. Dans ce projet, nous cherchons tout d'abord à expliquer via une simulateur acoustique, les résultats décevants obtenus avec le mode de stimulation bipolaire. Dans un deuxième temps nous tentons de mieux comprendre le comportement électrique de l'oreille interne implantée afin d'optimiser la stimulation multipolaire phased array (van den Honert et Kelsall 2007). Pour obtenir une stimulation efficace il faut par ailleurs s'assurer de l'état de la population neuronale à stimuler. Dans ce projet nous essayons donc de mieux comprendre l'interface électrode-neurones et d'identifier un possible corrélat psychophysique de l'état des neurones. Enfin nous discutons la possibilité de créer une stimulation optimale focalisée directement au niveau des neurones. / The cochlear implant is a neural prosthesis designed to restore an auditory sensation to people suffering from severe to profound sensorineural deafness. While satisfying speech recognition can be achieved in silence, their performance dramatically drop in more complex environments. One main limitations of the present device is due to the fact that each electrode stimulates a wide portion of the cochlea. As a result, when several electrodes are activated, the electrical field produced by different electrodes overlap which distorts the transmission of sound information. Several alternative stimulation modes have been proposed to overcome this issue but the benefit in terms of speech recognition remained limited. In this project, we first used an acoustic simulator of the cochlear implant to explain the desappointing results obtained with the bipolar stimuilation mode. We then try to better understand the electrical behavior of the implanted cochlea in order to optimize the multipolar phased array stimulation strategy ( van den Honert and Kelsall 2007). To achieve an efficient stimulation of the neural population it is necessary to determine the distribution of neural survival. In this project we aim to better understand the electrode-neuron interface and identify a possible psychophysical correlate of neural survival. Finally, we discuss the main results and the possibility to design an optimal stimulation strategy to achieve a spatially-focussed electrical field at the level of the nerve fibers.

Esta dissertação analisou a divisão social do espaço residencial intra-urbano a partir da sua relação com a desigualdade de renda. Utilizou-se como caso de estudo a cidade de Porto Alegre no período 1991-2000. A segmentação do espaço residencial urbano envolve a distribuição desigual dos poderes e direitos sobre a localização das moradias nas cidades, o que gera consequências significativas e duradouras nas características do tecido urbano, na formação de preços dos imóveis e no encontro entre grupos socialmente distintos. Duas hipóteses foram consideradas no presente estudo: a primeira hipótese associa a concentração de renda no espaço urbano à polarização socioespacial das áreas residenciais, nesta leitura os espaços residenciais estariam sofrendo um processo de homogeneização de renda combinado à redução dos espaços de classe média, esta hipótese aponta para a emergência de uma cidade dualizada entre ricos e pobres; a segunda hipótese associa a concentração de renda no espaço urbano ao aumento da seletividade e à fragmentação espacial das áreas residências dos estratos mais ricos, simultaneamente estaria ocorrendo o aumento da heterogeneidade dos espaços residenciais de classe média e dos pobres. Utilizou-se a variável renda do responsável por domicílio extraída do banco de dados dos Censos Demográficos de 1991 e 2000. O nível de desagregação da variável utilizada foi o setor censitário. As medidas de desigualdade de renda e de seletividade residencial utilizadas foram: índice de Gini, curva de Lorenz, renda relativa, curva de segregação, índice de dissimilaridade, índice de correlação espacial e análise de cartogramas. Os resultados encontrados apontam para a convergência das duas hipóteses. Por um lado, o espaço residencial dos mais ricos se tornou muito mais homogêneo, mas por outro lado, essas áreas estão relativamente mais concentradas no tecido urbano, demonstrando que a valorização territorial na década de 90 ocorreu principalmente nas adjacências de áreas que já eram ocupadas pelos mais ricos no início do período. Verificou-se também um relativo aumento da heterogeneidade do espaço da classe média e dos pobres, combinado à redução no percentual de domicílios nos espaços de classe média. Os resultados apontam para o aumento de domicílios nos espaços dos estratos superiores e inferiores de renda, o que sinaliza para uma polarização socioespacial. Conclui-se que a cidade de Porto Alegre se tornou mais desigual espacial e economicamente no período analisado. / This study examined the social division of intra-urban residential space from its relationship with income inequality. It was used as a case study the city of Porto Alegre in the period 1991-2000. The segmentation of urban residential space involves the unequal distribution of powers and rights on the location of housing units, which generates significant consequences on the spatial configuration, the pricing of real estate and in the encounter between different social groups. Two hypotheses were considered in this study: in the first hypothesis income inequality is associated with polarization of the residential areas, residential spaces in this reading would be undergoing a process of homogenization of income combined with the reduction of spaces for the middle class, this hypothesis points to the emergence of a dualized city between rich and poor; the second hypothesis associates the concentration of income in urban areas to increase the selectivity and the spatial fragmentation of the residential areas of the richest people, while there would be an increased heterogeneity of spaces middle class and poor people. We used the variable income per head of household extracted from the database of the population censuses of 1991 and 2000. The level of disaggregation of the variable used was the census sector. The measures of income inequality and residential selectivity were used: the Gini index, Lorenz curve, relative income, curve segregation, dissimilarity index, index of spatial correlation and analysis of maps. The results point to the convergence of two hypotheses. On the one hand, the richest of residential space has become much more homogeneous, but on the other hand, these areas are relatively more concentrated in the city, demonstrating that the recovery in the 90 territorial mainly occurred in the vicinity of areas that were already occupied by the rich at the beginning of the period. There was also a relative increase of the heterogeneity of the middle class and poor people, combined with the reduction in the percentage of households in the spaces of the middle class and increase in space from the upper and lower income, which points to a socio-spatial polarization. It is concluded that the city of Porto Alegre has become increasingly unequal spatial and economically in this period.