I Sverige genomförs kontinuerliga befolkningsundersökningar i syfte att ge information om indikatorer på ohälsa samt risk- och skyddsfaktorer. Resultaten av dessa presenteras i olika nationella redogörelser samt landstingsrapporter. Det finns idag ingen aktuell sammanställning av ohälsans utveckling med värden för enbart Uppsala län, denna uppsats avsåg därför att bidra med detta. Resultaten visade på en minskning i den självskattade dåliga hälsan över tid, då materialet delades upp på kön och ålder. En relativ ökning av skillnaderna i ohälsa mellan förvärvsarbetande, arbetslösa och förtidspensionerade kunde också observeras. Den relativa ökningen syntes tydligast mellan förvärvsarbetande och förtidspensionerade. Riskfaktorer som visade sig särskilt effektfulla till att skatta sin hälsa som dålig eller mycket dålig var mycket dålig trivsel med sina arbetsuppgifter, svåra besvär med trötthet och svåra besvär med ängslan oro eller ångest. Vidare upplevde sig arbetslösa i högre utsträckning vara utsatta för riskfaktorn nedlåtande behandling, vilket är i linje med tidigare presenterade resultat. Resultaten i uppsatsen kan vara till hjälp vid planering för folkhälsoarbete mot skillnader i hälsa och för en god och jämlik hälsa i Uppsala län. Ifall insatserna på området behöver prioriteras kan denna uppsats vara till hjälp då den lyfter fram de förtidspensionerades utsatta situation. Eftersom den självskattade dåliga hälsan bland övriga sysselsättningsgrupper inte har förbättras under de senaste åren, kan det vara en fingervisning om att pågående insatser bör ses över. Då denna studie bekräftade tidigare resultat avseende arbetslösas upplevelse av nedlåtande behandling och dess effekt på hälsan, tyder det på att folkhälsoarbetet i länet kan lägga visst fokus på detta problem. / In Sweden continuous population surveys operates to provide information on indicators of poor health and risk and protective factors. There is currently no current compilation of ill health development of values for only Uppsala County; this paper therefore intended to contribute to this. When the material was divided by gender and age, the results showed a decrease in self-rated bad health. Also the results showed a relative increase of differences in health between occupational groups. The relative increase was shown most distinct between the employed and the early retired. Risk factors that proved particularly effective at estimating their health as poor or very poor were very poor satisfaction with your work, severe problems with fatigue, and severe problems with anxiet, worry or anxiety. Furthermore unemployed perceived themselves being exposed to the risk factor condescending treatment, which is in line with previously announced results. Therefore this paper can be helpful in planning for public health efforts to combat health disparities and for a good and equitable health in the county. If the efforts in this area need to be prioritized, then this essay can be helpful when it highlights the early-retired vulnerable situation. Since the self-rated poor healths among other employment groups haven’t improved in recent years, it may be a hint that the ongoing efforts should be reviewed. As this study confirmed previous findings regarding the unemployed experience of condescending treatment and its effect on health, it indicates that public health efforts may put some focus on this problem.

Background: It is debated whether temporary employment compared to permanent employment entails an elevated risk of illness or not, as the empirical studies have not shown a unified picture. Since a significant part of the Swedish workforce is currently working under temporary employment contracts, it is important for public health research to pay close attention to what the implications in terms of illness might be. Therefore the aim of this thesis was to explore the relationship between temporary employment and illness. Methods: This thesis was based on data from the Northern Swedish Cohort, consisting of all pupils in grade 9 in Luleå in 1981 (n=1083). The cohort was followed with extensive questionnaires. The latest follow-up was performed in year 2007, when 94% participated. To analyse the quantitative questionnaire data, logistic regression and trajectory analysis were used. A qualitative method, Grounded Theory, was also applied in this thesis to analyse interviews performed in 2011, with a strategic selection of 12 participants from the cohort. Results: Quantitative data showed that temporary employees had overall higher odds ratios for illness in terms of psychological distress and non-optimal self-rated health compared to permanent employees. This general difference in odds ratios was evident irrespective of how temporary employment was measured as well as after control for earlier health status and confounders. The qualitative analysis gained insight into temporary employment as social processes of: underling the driving force for employment; working hard for a job. The structural conditions emerged in terms of, being used and exploited on the labour market and these conditions were related to the individual strategies of adaptation and coping. In the intersection of agency, structural conditions and adaption, emotional and bodily reactions emerged, such as being worn out, worried and wrathful. Conclusion: Illness is unevenly distributed between temporary and permanent employees, with temporary employees being the unfavourable group. Striving for good and evenly distributed health conditions in the population, policy makers should aim at reducing the number of employees working in temporary contracts. In addition, there is a need to improve surveillance of the health situation among temporary employees and to reduce unfavourable conditions, such as job and financial insecurity and unemployment, among temporary employees.

Background: Many of today’s young adults suffer from impaired psychological well-being and report suffering from psycho-somatic symptoms related to stress. Lifestyle factors, such as smoking, risky alcohol consumption, lack of physical activity and poor diet are known predictors of ill health and may have long lasting impacts on young people’s lives. Aim: The aim of this thesis was to 1: measure adult high school students’ social capital and 2: examine the association between their social capital and psychological well-being as well as the association between social capital and the lifestyle factors; smoking, alcohol consumption, physical activity, diet and academic achievement. Methods: Questionnaires were used to measure high school students’ social capital self- rated psychological health, lifestyle factors and academic achievement. Participants were high school students 18 years and older (n=124) enrolled in Nacka Enskilda Gymnasium and Mörby Gymnasium, two high schools in counties with similar demographic backgrounds, measured in annual salaries, on the outskirts of Stockholm, Sweden. Results: Total social capital was significantly associated with no less than 6 factors of health; self-rated mental health, self-rated stress, psycho-somatic symptoms, intensive physical exercise, consumption of fruit and membership to a club. In addition, consumption of vegetables and expected grade point average (Grade point average (GPA): final GPA’s in Sweden range from 0-20) were significantly associated with individual factors of social capital. Conclusion: The results of this study support the findings of many earlier studies; that social capital appears to be significantly associated with young peoples’ health and well-being. The findings lend weight to earlier studies and contribute to the multitude of voices that lobby for investing in the further development of policies and interventions that aim to increase young peoples’ social capital.

Syfte: Syftet med denna studie var att kartlägga långtidssjukskrivnas hälsa före och efter avslutad intervention samt studera vilka faktorer som hindrat alternativt främjat återgång i arbete hos individer med tidsbegränsad sjukersättning. Metod: Studien baseras på data från EU-projektet ”SAMKLANG” som är en longitudinell interventionsstudie. Data har samlats in på 59 långtidssjukskrivna deltagare via enkäter både före projektstart och ett år efter och dels har data samlats in kvalitativt genom semistrukturerade intervjuer med 13 deltagare efter det att projektet avslutats. Intervjudeltagarna var indelade i två grupper (de som hade återgått i arbete/studier och de som fortfarande var sjukskrivna). Interventionen bygger på både behandling och samverkan mellan organisationer som är involverade i rehabilitering av personer som har ett år kvar av sin tid i sjukersättning. Resultatet från enkäterna analyserades fram via ANOVA upprepad mätning och data från intervjuerna analyserades via innehållsanalys. Resultat: Huvudresultaten från den kvantitativa delstudien visade att det inte fanns någon skillnad mellan de som efter ett år återgått i arbete/studier, arbetsträning alternativt de som fortfarande var sjukskrivna gällande kön, ålder eller utbildningsnivå. Den självskattade depressions- och ångestnivån minskade och självskattad hälsa och inre kontroll ökade signifikant över tid för den grupp som kommit ut i arbete efter projektet jämfört med de två andra grupperna. Den kvalitativa analysen av intervjuerna identifierade följande tema som stödjande faktorer för arbetsåtergång: att besitta egen drivkraft, ha en insikt om arbetets mervärde och att hitta en balans mellan krav- kontroll-stöd. Det tema som beskriver hur myndigheter kan hjälpa och stödja långtidssjukskrivna tillbaks i arbete är: trygghet med mer vårdkompetens och att synliggöra individuella behov. Slutsats: Att återgå i arbete för en tidigare långtidssjukskriven person kopplas till bättre självrapporterad hälsa med mindre depression och ångestbesvär, en starkare känsla av inre kontroll och en högre tilltro till egen förmåga jämfört med om personer fortfarande är sjukskrivna. Framgångsfaktorer för arbetsåtergång är balans mellan krav, kontroll och stöd för individen och en egen motivation att återgå i arbete. För att underlätta arbetsåtergång hos långtidssjukskrivna bör myndigheter och inblandade parter samverka med vård, erbjuda trygghet och synliggöra varje enskild individs behov av rehabilitering. / Aim: The aim of this study was to investigate long term sickness absentees’ health status before and after an intervention. Furthermore, to gain deeper understanding of factors related to promoting and preventing return to work for people with limited sick leave compensation. Method: The study is based on data from the EU-funded project ”SAMKLANG” which is a longitudinal intervention study. Data has been collected from 59 long term absentees though questionnaires conducted before and one year after the start of the project. Data has also been collected through semi structured interviews from 13 participants after the end of the project. They were divided into two groups (those who had returned to work/studies or had an internship and those who still were sickness absent). The intervention is based on treatment as well as cooperation between organizations involved in a rehabilitation process for people with one year of sick leave compensation remaining. The results from the surveys were analyzed with ANOVA for repeated measures and data from the interviews were analyzed using content analysis. Result: The main result from the quantitative part of this study showed no significant difference in return to work between those who had returned to work or studies, been on internships and those who still were sickness absent based on sex, age and education. The amount of self-rated depression and anxiety levels were reduced and the self-rated health and internal control were significant induced over time for the group who returned to work after the project compared to the other two groups. From the qualitative analyze of the interviews following theme was identified as supporting factors for returning to work: having own motivation, realized the positive in having a job and to have balance between demand-control-support. The theme that describes how the authority can help and support people with long term sickness absence back to work is: security with more competence in healthcare and make individual needs visible. Conclusion: Return to work for a former long term sickness absence is associated with better self-rated health with less depression and anxiety, a stronger feeling of internal control and a higher self-efficacy compared to if persons still were sickness absent. Factors for success in return to work is balance between demand-control-support for the individual and an own motivation to return to work. The authority can facilitate return to work among people with long term sickness absence by interact more with health-care services, offer security and make every individuals need for rehabilitation visible.

The mental-health consequences of childlessness have been well documented and the perception is that women are more likely than men to experience lower mental well-being, including emotional distress, as a result of childlessness; despite the fact that very few studies have focused on the implications for men. Thus, employing OLS multiple regression we seek to examine: (1) the association between childlessness and emotional distress and whether the risk was greater among men or women. (2) Whether there is significant variation in emotional distress among childless individuals after controlling for socio-demographic factors. The data was derived from the Estonian Health Interview Survey, collected in 2006 and 2007. The survey was a multi-stage random sample of the Estonian Population aged 15-85. Under study was men and women aged 40 and above (N=4294).The outcome variable- emotional distress is based on the emotional state questionnaire (EST-Q), a self-rated health measure. The simple regression and multivariate OLS regressions indicated higher predicted levels of emotional distress symptoms for childless men when compared to childless women. In comparison, the interactions revealed more distress among childless women. Overall, the results garnered indicate that educational attainment and personal income ameliorates the negative mental health consequences of childlessness. However, the degree and manner in which childlessness matter differ by gender, ethnicity and relationship status, but was inconclusive for age. An unexpected finding from the interaction models was the high level of distress among women that were parents. In general, the outcomes point to other reasons for the higher levels of distress among women. The mental-health consequences of childlessness have been well documented and the perception is that women are more likely than men to experience lower mental well-being, including emotional distress, as a result of childlessness; despite the fact that very few studies have focused on the implications for men. Thus, employing OLS multiple regression we seek to examine: (1) the association between childlessness and emotional distress and whether the risk was greater among men or women. (2) Whether there is significant variation in emotional distress among childless individuals after controlling for socio-demographic factors. The data was derived from the Estonian Health Interview Survey, collected in 2006 and 2007. The survey was a multi-stage random sample of the Estonian Population aged 15-85. Under study was men and women aged 40 and above (N=4294).The outcome variable- emotional distress is based on the emotional state questionnaire (EST-Q), a self-rated health measure. The simple regression and multivariate OLS regressions indicated higher predicted levels of emotional distress symptoms for childless men when compared to childless women. In comparison, the interactions revealed more distress among childless women. Overall, the results garnered indicate that educational attainment and personal income ameliorates the negative mental health consequences of childlessness. However, the degree and manner in which childlessness matter differ by gender, ethnicity and relationship status, but was inconclusive for age. An unexpected finding from the interaction models was the high level of distress among women that were parents. In general, the outcomes point to other reasons for the higher levels of distress among women.

Studies in countries across the globe and in Canada show that people from minority communities generally tend to be in poorer health, experience a greater burden of disease and disability than the general population. A 2008 World Health Organization (WHO) report on the Social Determinant of Health stressed that the high burden of disease and disability around the world is due to a great extent, to poor and unequal living conditions which are the consequence of deeper structural conditions such as poor social policies and programmes, inequitable economic structures, and deficient politics. In Canada, there is a growing body of evidence suggesting a negative impact of health disparities on Official Language Minority Communities (OLMCs), especially on Francophones outside of Quebec. In order to better describe and understand the situation of Official Language Minorities (OLMs), especially of Minority Francophone older adults living outside of Quebec, two national surveys were used: The 2006 Canadian post-census Survey on the Vitality of Official Language Minorities (SVOLM) and the 2007 Canadian Community Health Survey (CCHS). Descriptive, and multivariable analyses were conducted, followed by minority Francophone community members’ feedback on the findings. A qualitative analysis of provincial/territorial French-language (English in Quebec) services policies or legislations was subsequently conducted with an in-depth focus on the Government of Saskatchewan French-language Services Policy and an assessment of the potential impact of these policies on the health of OLM older adults. This study showed that minority Francophone older adults consistently rated their health more poorly than their counterparts in the general population but the study failed to demonstrate an association between OLM status and self-rated health, due to low representativity of the OLM population in the sample. However, the sense of belonging to, and vitality of minority community were constructs associated with better self-rated health for minority Francophone older adults while high concentration of minority group was associated with poorer self-rated health. Feedback from Francophone community members emphasized the detrimental role of assimilation, systemic and structural inequities, and unfavourable policies as contributing significantly to the low vitality of their communities and eventually to health disparities. Adopting new sampling approaches for OLMs, addressing minority Francophones’ contextual realities, enhancing access to health services in French, improving the linguistic environment, and developing more supporting policies, would help improve the condition of minority Francophone older adults in Canada.

Translational research suggests that agonist replacement may be a viable treatment approach for managing methamphetamine dependence. This study sought to determine the effects of d-amphetamine maintenance on methamphetamine self-administration in stimulant using participants. A cognitive battery was used to determine the performance effects of methamphetamine alone and during d-amphetamine maintenance. During each maintenance condition, participants first sampled a dose of intranasal methamphetamine then had the opportunity to respond on a progressive ratio task to earn portions of the sampled dose. Subject-rated drug-effect and physiological measures were completed prior to and after sampling methamphetamine. Methamphetamine was self-administered as function of dose regardless of the maintenance condition. Methamphetamine produced prototypical subject-rated effects, some of which were attenuated by d-amphetamine maintenance. Methamphetamine was well tolerated during d-amphetamine maintenance and no adverse events occurred. The self-administration results are concordant with those of clinical trials that show d-amphetamine did not reduce methamphetamine use. Generally, there was no difference in cognitive performance after methamphetamine administration during both placebo and d-amphetamine maintenance. Overall d-amphetamine does not appear to be a viable treatment for preventing methamphetamine relapse, but translational literature suggests that other agonist medications or the combination of pharmacotherapy and behavioral therapies may be effective.

Background; The overwhelming increase in studies about social capital and health occurring since 1995 indicates a renewed interest in the social determinants of health and a call for a more explicit use of theory in public health and epidemiology. The links between social capital and health are still not clear and the meanings of different forms of individual and collective social capital and their implications for health promotion needs further exploration. The overall aims of this thesis are to explore the relationship between social capital and health and to contribute to the theoretical framework of the role of social capital for health and health promotion. Methods; Data from a social capital survey were used to investigate the associations between individual social capital and self-rated health for men and women and different educational groups. Survey data were also analyzed to determine the association between collective social capital and self-rated health for men and women. A qualitative case study in a small community with observed high levels of civic engagement formed the basis for exploring the role of social capital for community action. Data from the same study were utilized for a grounded theory situational analysis of the social mechanisms leading to social capital mobilization. Main findings; Access to individual social capital increases the odds for good self-rated health equally for men and women and different educational groups. However, the likelihood of having access to social capital differs between groups. The results indicate a positive association between collective social capital and self-rated health for women but not for men. Results from the qualitative case study illustrate how social capital in local communities can facilitate collective actions for public good but may also increase social inequality. Mobilizing social capital in local communities requires identification of community issues that call for action, a fighting spirit from trusted local leaders, “know-how” from creative entrepreneurs, and broad legitimacy and support in the community. Conclusions; This thesis supports the idea that individual social capital is health-enhancing and that strengthening individual social capital can be considered one important health promotion strategy. Collective social capital may have a positive effect on self-rated health for women but not for men and therefore mobilizing collective social capital might be more health-enhancing for women. Collective social capital may have indirect positive effects on health for all by facilitating the ability of communities to solve collective health problems. However, mobilizing social capital in local communities requires an awareness of the risk for increased social inequality.

Background Most aging research comes from the developed world. Aging research in India is focused on disease states and risk factors. Evidence on elderly health, physical performance and disability to understand the psycho-social or socio-behavioral risk is limited in India. Self-rated health (SRH) is used often in survey settings to quickly assess health status and is known to predict morbidity and mortality. The first wave of the Study on global AGEing and adult health (SAGE) survey provides an opportunity to explore the complex construct of SRH in the context of the aging process in its various key life domains of health, disability, cognition, activities of daily life, work, family, security and well-being in low and middle income settings. Objectives This research aims to (a) understand pathways through which the social environment, functional disability, health behaviour and chronic disease experience influence SRH, (b) examine the role of SRH in predicting mortality, (c) validate SRH to improve its interpersonal comparability, and (d) assess how well estimates of SRH derived directly from a ‘small area’ survey compare with ‘small area’ estimates derived indirectly from a ‘large area’ survey. Methods The Vadu Health and Demographic Surveillance System (HDSS) monitor health and demographic trends in a rural population of more than 100 000 in 22 villages in India since 2002. The full and short version of the SAGE survey was implemented in Vadu in 2007-09 among 321 and 5432 individuals aged 50 years and above, respectively. A structural equation model tested pathways through which social and biological factors influenced SRH. A Cox proportional hazard model examined the role of SRH as a predictor for mortality. Anchoring vignettes were used to evaluate SRH for reporting heterogeneity. The Hierarchical Ordered Probit model adjusted SRH for reporting heterogeneity. The SRH prevalence estimates for Vadu derived indirectly (indirect synthetic estimate, empirical Bayes estimate, Hierarchical Bayes estimate) from the national SAGE survey were compared with estimates derived directly from the Vadu SAGE survey, using different design and model-based techniques. Results Older individuals reported poor SRH compared to those younger. Women rated their quality of life and SRH poorer than men. The effect of age on SRH was mediated through functional disability. Higher socioeconomic status and higher quality of life was in turn associated with better SRH but this relationship lacked statistical significance. Smoking or consumption of tobacco was associated with at least one chronic illness which in turn was associated with poor SRH and quality of life. However the association between chronic illness and SRH and quality of life was not statistically significant. Mortality risk was higher among individuals who reported bad/very bad SRH, disability and lack of spousal support independent of age and sex. There was strong evidence of reporting heterogeneity in SRH that was influenced by age, sex, education and socioeconomic status. The prevalence of ‘good / very good’ SRH was estimated to be 50%. This direct survey estimate compared well with the prevalence estimate of about 45% derived indirectly from model-based small area estimation methods. The indirect synthetic estimate for Vadu (23.2%) was a poor approximation to the direct survey or modelbased estimate. Conclusion This research establishes the value and utility of SRH as a simple measure of health and predictor of mortality in an aging context. It provides evidence to formulate programs and policies towards an enabling social environment and an ability to function in key life domains of health and well-being. It highlights the need to identify and adjust self-rated responses for interpersonal incomparability prior to making comparisons across individuals or groups of individuals. It highlights the potential of using information from large national surveys by district level managers for planning and evaluation of policies and programs at the district or sub-district level. Finally, this research provides the basis for integrating SRH and related questions into routine HDSS.

Tyrimo tikslas – ištirti moterų, sergančių krūties vėžiu, savo įvertintos sveikatos ir savijautos ypatybes aktyvaus gydymo laikotarpiu. Tyrime dalyvavo 105 krūties vėžiu sergančios moterys, besigydančios Vilniaus universiteto Onkologijos instituto III-iajame onkochirurgijos skyriaus krūties ligų chirurgijos ir onkologijos poskyryje. Tyrimo dalyvės buvo atrenkamos pagal šiuos kriterijus: moteriška lytis, nustatyta I-IV krūties vėžio stadija (karcinoma), laukiama arba jau padaryta krūties vėžio operacija gydantis stacionare, sutikusios dalyvauti tyrime. Siekiant įvertinti sergančių krūties vėžiu moterų sveikatą, pablogėjusią nuotaiką ir nusiskundimus sveikata buvo naudojamas subjektyviai vertinamos sveikatos klausimynas, pablogėjusios nuotaikos vertinimo metodika ir klinikinis struktūruotas interviu apie nusiskundimus sveikata, savijauta (Goštautas, 1998). Taip pat buvo naudojama Beko depresijos skalė – II. Norint įvertinti dėl krūties vėžio operacijos kylančius sunkumus buvo naudojama įvykio poveikio skalė – revizuota lietuviška versija (Kazlauskas, Gailienė, Domanskaitė-Gota, Trofimova, 2006). Trauminiams įvykiams vertinti Vrana-Lauterbach trauminių įvykių klausimynas civiliams (Vrana, Lauterbach, 1994). Taip pat buvo taikytas pusiau struktūruotas interviu įvertinti dėl krūties vėžio kylančius pokyčius, prašoma užpildyti klinikinius ir sociodemografinius duomenis. Atlikus tyrimą, buvo įvertinamas asmens elgesys naudojant emocinės įtampos skalę. Tyrimo rezultatai parodė... [toliau žr. visą tekstą] / The aim of the research is to analyze peculiarities of the self – rated health and general condition during the period of active treatment among women with breast cancer. In this research were participating 105 women with breast cancer, at this time treated in Vilnius University Institute of Oncology of breast disease surgery and oncology section of III-rd oncosurgery department. Participants of the research were selected by these criterions: female, I-IV stage of cancer diagnosed (carcinoma), expected or already done for breast cancer surgery during stationary treatment, agreed to participate in the research. In order to assess health, mood and health complaints among women with breast cancer were used self – rated health questionnaire, mood assessment methodology and clinical structured interview about complaints of health and general condition (Goštautas, 1998). Also been used Beck Depression Scale - II. To evaluate for breast cancer surgery the difficulties were used the Impact of Event Scale – the revised Lithuanian version (Kazlauskas, Gailienė, Domanskaitė-Gota, Trofimova, 2006). To assess traumatic events were used Vrana-Lauterbach traumatic events questionnaire for civilians (Vrana, Lauterbach, 1994). In addition, the semi-structured interview was used to assess the changes that result from breast cancer, and asked to complete the clinical and socio-demographic data. In order to assess behavior of women immediately after the research was used observational scale of... [to full text]