Às condições crônicas podem causar alterações físicas, psíquicas e sociais progressivas requerendo em alguns casos mudanças permanentes no estilo de vida dos indivíduos. A paracoccidioidomicose é uma micose sistêmica, que exige tratamento prolongado, cuja maior prevalência encontra-se na América Latina com diversas áreas endêmicas no Brasil. Este estudo teve como objetivo caracterizar os clientes portadores de paracoccidioidomicose cutânea mucosa e identificar os motivos da não adesão ao seguimento clínico terapêutico. Foram consultados 74 prontuários de clientes adultos com diagnóstico de paracoccidioidomicose cutâneo mucosa atendidos e ou internados em um hospital escola terciário do interior paulista, no período de janeiro de 2000 a junho de 2006. O projeto foi encaminhado ao Comitê de Ética em Pesquisa do referido hospital. A maioria dos sujeitos é do sexo masculino (86,5%), com idade médica de 44,5 anos, 67,6% dos casos foram internados de uma a oito vezes, em 50,0% dos casos a internação se deu em decorrência de recidivas e 74,3% fizeram uso irregular das medicações e houve o abandono do tratamento por 54% dos clientes. O enfermeiro enquanto elemento essencial nos serviços de saúde pode propor estratégias individuais e coletivas para a assistência, visando estimular o cliente a lidar com as mudanças e consquentemente melhorar os níveis de adesão ao seguimento. / The chronical conditions can cause physical, emotional and social progressive alterations, requiring in some situations permanent changes in people life style. Paracoccidioidomycosis is a systemic mycosis, that requires a long-term treatment and its higher prevalence is in Latin America with different endemic areas in Brazil. This study aimed to characterize the clients carrie cuataneous mucosal paracoccidioidomycosis and to identify the reasons of non adhesion to clinical therapeutical follow-up. A total of 74 patient file were consulted of adults clients cared and/or interned is a teaching hospital of the interior of São Paulo State, in the period January 2000 through June 2006. The project was approved by the Ethical and Research Commitment of the hospital. Most of the participants was male (86,5%), with average age of 44,5 years old, 67,6% of the cases were interned from one to eight times and in 50,0% of the cases the hospitalization occurred due to recidives and 74,3% took the medicine in a irregular way, there was also the abandonment of the treatment in 54,0%. The nurse as the essencial member of health services can propose individual and collective strategies to the caring, in order to incentivate the client to deal with the changes and in consequence to improve the levels of adhesion to the follow-up.

Às condições crônicas podem causar alterações físicas, psíquicas e sociais progressivas requerendo em alguns casos mudanças permanentes no estilo de vida dos indivíduos. A paracoccidioidomicose é uma micose sistêmica, que exige tratamento prolongado, cuja maior prevalência encontra-se na América Latina com diversas áreas endêmicas no Brasil. Este estudo teve como objetivo caracterizar os clientes portadores de paracoccidioidomicose cutânea mucosa e identificar os motivos da não adesão ao seguimento clínico terapêutico. Foram consultados 74 prontuários de clientes adultos com diagnóstico de paracoccidioidomicose cutâneo mucosa atendidos e ou internados em um hospital escola terciário do interior paulista, no período de janeiro de 2000 a junho de 2006. O projeto foi encaminhado ao Comitê de Ética em Pesquisa do referido hospital. A maioria dos sujeitos é do sexo masculino (86,5%), com idade médica de 44,5 anos, 67,6% dos casos foram internados de uma a oito vezes, em 50,0% dos casos a internação se deu em decorrência de recidivas e 74,3% fizeram uso irregular das medicações e houve o abandono do tratamento por 54% dos clientes. O enfermeiro enquanto elemento essencial nos serviços de saúde pode propor estratégias individuais e coletivas para a assistência, visando estimular o cliente a lidar com as mudanças e consquentemente melhorar os níveis de adesão ao seguimento. / The chronical conditions can cause physical, emotional and social progressive alterations, requiring in some situations permanent changes in people life style. Paracoccidioidomycosis is a systemic mycosis, that requires a long-term treatment and its higher prevalence is in Latin America with different endemic areas in Brazil. This study aimed to characterize the clients carrie cuataneous mucosal paracoccidioidomycosis and to identify the reasons of non adhesion to clinical therapeutical follow-up. A total of 74 patient file were consulted of adults clients cared and/or interned is a teaching hospital of the interior of São Paulo State, in the period January 2000 through June 2006. The project was approved by the Ethical and Research Commitment of the hospital. Most of the participants was male (86,5%), with average age of 44,5 years old, 67,6% of the cases were interned from one to eight times and in 50,0% of the cases the hospitalization occurred due to recidives and 74,3% took the medicine in a irregular way, there was also the abandonment of the treatment in 54,0%. The nurse as the essencial member of health services can propose individual and collective strategies to the caring, in order to incentivate the client to deal with the changes and in consequence to improve the levels of adhesion to the follow-up.

Compliance monitoring is a continuous process used to ensure that conditions stipulated in an environmental authorisation are adhered to. Compliance monitoring is a key component of Environmental Impact Assessment (EIA) and EIA follow-up. The aim of this research was to critically assess EIA follow-up conditions formulated for Environmental Authorisations in Mpumalanga Province. The practicability of conditions set out in the authorisation for EIA follow-up are of particular concern. Forty-two (42) environmental authorisations (EAs) issued under the 2010 NEMA EIA regulations were reviewed and assessed to analyse information relating to follow-up practice. In order to synthesise the data effectively and create a comprehensive analysis, the EAs were divided into project type categories rather than listed activity categories. The assessment results on the strengths and weaknesses related to compliance monitoring and enforcement of the authorisation conditions revealed that the EIA follow-up conditions in Mpumalanga do make provision of EIA follow-up. The EAs fulfils the requirements of regulation 37 of the NEMA EIA regulations 2010 by promoting compliance monitoring of impacts. However, some conditions raises difficulty in monitoring due to their impracticability. Another weakness is that conditions focus mainly on the construction phase and very little attention is paid to operational and decommissioning impacts. The analyses results show that the practicability of the authorised conditions for environmental compliance monitoring had the following challenges: conditions intended to mitigate the adverse environmental impacts are generic and do not apply to specific projects or activities being authorised and there are no clearly defined timeframes for conditions requiring repetitive monitoring. Moreover, the study revealed gaps in monitoring of the authorised conditions that included poor clarity of roles of environmental control officers (ECOs) and auditors and a lack of reference to sections to be complied with pertaining to other relevant legislation. The critical assessment of the EIA follow-up conditions formulated for Environmental Authorisations in Mpumalanga Province indicate that the formulation of conditions have implications in ensuring that compliance is effectively implemented. Clearly defined conditions will ensure proper interpretation and correct implementation for compliance purposes. / M (Environmental Management), North-West University, Potchefstroom Campus, 2015

Compliance monitoring is a continuous process used to ensure that conditions stipulated in an environmental authorisation are adhered to. Compliance monitoring is a key component of Environmental Impact Assessment (EIA) and EIA follow-up. The aim of this research was to critically assess EIA follow-up conditions formulated for Environmental Authorisations in Mpumalanga Province. The practicability of conditions set out in the authorisation for EIA follow-up are of particular concern. Forty-two (42) environmental authorisations (EAs) issued under the 2010 NEMA EIA regulations were reviewed and assessed to analyse information relating to follow-up practice. In order to synthesise the data effectively and create a comprehensive analysis, the EAs were divided into project type categories rather than listed activity categories. The assessment results on the strengths and weaknesses related to compliance monitoring and enforcement of the authorisation conditions revealed that the EIA follow-up conditions in Mpumalanga do make provision of EIA follow-up. The EAs fulfils the requirements of regulation 37 of the NEMA EIA regulations 2010 by promoting compliance monitoring of impacts. However, some conditions raises difficulty in monitoring due to their impracticability. Another weakness is that conditions focus mainly on the construction phase and very little attention is paid to operational and decommissioning impacts. The analyses results show that the practicability of the authorised conditions for environmental compliance monitoring had the following challenges: conditions intended to mitigate the adverse environmental impacts are generic and do not apply to specific projects or activities being authorised and there are no clearly defined timeframes for conditions requiring repetitive monitoring. Moreover, the study revealed gaps in monitoring of the authorised conditions that included poor clarity of roles of environmental control officers (ECOs) and auditors and a lack of reference to sections to be complied with pertaining to other relevant legislation. The critical assessment of the EIA follow-up conditions formulated for Environmental Authorisations in Mpumalanga Province indicate that the formulation of conditions have implications in ensuring that compliance is effectively implemented. Clearly defined conditions will ensure proper interpretation and correct implementation for compliance purposes. / M (Environmental Management), North-West University, Potchefstroom Campus, 2015

The purpose of this study was to examine the experiences and perceptions of behavioral factors that contribute to successful weight loss in male bariatric patients. By analyzing participant experiences and perceptions, this study contributes to a better understanding of which factors are most important in the postoperative phase of gastric bypass in males owing to successful weight loss. Although there is a tremendous amount of quantitative research within the bariatric population, there is a significant gap within the qualitative literature as it relates to male outcomes. As such, by conducting interviews with 10 postoperative male gastric bypass patients, this study was able to further understand how and why these participants obtained successful weight loss. Furthermore, by identifying relevant categories and thematic responses from the participants, this study may serve future researchers in designing other qualitative studies that target best practices in males for successful weight loss outcomes. The findings of this study indicate that participants found greater weight loss success by following proper eating behaviors and engaging in physical activity whereas support group attendance was not found to be an important factor in successful weight loss. This study also revealed that follow up with the bariatric nurse coordinator was greatly viewed as a positive step in adjusting to lifestyle postsurgery. As such, this supportive role by the nurse coordinator may provide further impetus for the ways in which bariatric personnel interact with patients who might not always be able to see their surgeon for follow-up.

As habilidades comunicativas de crianças portadoras de deficiência auditiva (DA) pré-lingual, submetidas à cirurgia do implante coclear (IC) desenvolvem-se ao longo dos anos de uso do dispositivo. O objetivo deste trabalho foi estudar o desempenho alcançado por adolescentes e jovens adultos com, no mínimo, dez anos de experiência com o IC, em relação à audição e à inteligibilidade de fala e, considerando o tipo de DA, o tempo de privação sensorial auditiva e o tipo de dispositivo. Participaram deste estudo, 61 adolescentes e jovens adultos portadores de DA pré-lingual, que receberam diferentes tipos de IC em média, aos 3 anos e 10 meses de idade. Reconhecimento da lista de palavras dissílabas, Teste Hint adaptativo e reconhecimento das sentenças Hint no silêncio e no ruído foram os procedimentos utilizados para avaliar o desempenho de audição. A inteligibilidade da fala dos participantes foi avaliada por dois julgadores sem experiência com deficientes auditivos, usando o método de transcrição e a escala de inteligibilidade de 5 pontos. Após 10 anos de experiência com o IC, 53 participantes (86,9%) alcançaram habilidade de reconhecimento auditivo em conjunto aberto. Os resultados médios obtidos na lista de palavras dissílabas foram de 49,4%; teste Hint adaptativo, a média dos resultados no silêncio foi igual a 54,7dB e, no ruído, 10,7 dB e; os valores médios de porcentagem nas sentenças Hint no silêncio 54% e no ruído, 33,3%. Quanto à inteligibilidade de fala dos participantes, a média de acertos no método de transcrição foi igual a 76,2%. Na escala de inteligibilidade, a pontuação média correspondeu a 3,3 pontos. Melhores desempenhos de audição no silêncio e no ruído foram correlacionados ao menor tempo de privação sensorial auditiva. Foi observada correlação entre o tipo de dispositivo utilizado e: o desempenho de audição no ruído e o desempenho de inteligibilidade da fala. Usuários do dispositivo Nucleus 24 e Med-El apresentaram melhor desempenho de audição e de inteligibilidade de fala do que os usuários Nucleus 22. Mais de 10 anos após a cirurgia de IC, 82% das crianças implantadas com as primeiras gerações do dispositivo eletrônico desenvolveram habilidade de reconhecimento auditivo no ruído e 90,1% alcançaram fala inteligível. O desempenho de audição e de inteligibilidade de fala dos participantes foi influenciado pelo tempo de privação sensorial auditiva e pelo tipo de dispositivo eletrônico. Considerando os critérios contemporâneos de indicação cirúrgica em associação as novas estratégias de codificação de fala disponíveis nos dispositivos eletrônicos da atualidade, resultados promissores são esperados para a nova geração de crianças submetidas ao IC / The communication skills of prelingually deafened children, underwent cochlear implant (CI) surgery, develop over the years of device use. The aim of this work was to study the performance achieved by teenagers and young adults with at least ten years of IC experience with regard to speech perception and speech intelligibility and, considering the type of hearing loss, duration of deafness, and type of device. Participated of this study, 61 teenagers and young adults prelingually deafened, who received different types of CI, on average at 3 years and 10 months of age. Recognition of two-syllable word list, test Hint and recognition of Hint sentence in quiet and noise were the procedures used to evaluate the hearing performance. The speech intelligibility of the participants was evaluated by two judges, using the writedown intelligibility method and a 5-points intelligibility rating-scale. After 10 years of experience with CI, 53 participants (86,9%) achieved open-set speech recognition. The average results obtained in the two-syllable word list were 49, 4%; in the test Hint in quiet, the average results were 54,7 dB in quiet and 10,7 dB in noise and; the mean percentage of Hint sentences in quiet was 54% and in noise, 33,3%. Regarding the speech intelligibility of the participants, the average write-down intelligibility score was 76,2% and the average rating-scale intelligibility score was 3,3 points. Better speech performances in quiet and in noise were correlated with shorter duration of deafness. Correlation was found between the type of device and: the speech perception in noise and the speech intelligibility. Nucleus 24 and Med-El device users performed better than Nucleus 22 users with regard to speech perception in noise and speech intelligibility. More than 10 years after the CI surgery, 82% of children implanted with the first generation of the electronic device developed speech recognition in noise and 90,1% achieved intelligible speech. Speech perception and speech intelligibility of the participants, both were influenced by duration of deafness and type of electronic device. Considering the contemporary criteria of surgical indication in association with the new speech coding strategies available, promising results were expected for the new generation of children underwent to CI

As habilidades comunicativas de crianças portadoras de deficiência auditiva (DA) pré-lingual, submetidas à cirurgia do implante coclear (IC) desenvolvem-se ao longo dos anos de uso do dispositivo. O objetivo deste trabalho foi estudar o desempenho alcançado por adolescentes e jovens adultos com, no mínimo, dez anos de experiência com o IC, em relação à audição e à inteligibilidade de fala e, considerando o tipo de DA, o tempo de privação sensorial auditiva e o tipo de dispositivo. Participaram deste estudo, 61 adolescentes e jovens adultos portadores de DA pré-lingual, que receberam diferentes tipos de IC em média, aos 3 anos e 10 meses de idade. Reconhecimento da lista de palavras dissílabas, Teste Hint adaptativo e reconhecimento das sentenças Hint no silêncio e no ruído foram os procedimentos utilizados para avaliar o desempenho de audição. A inteligibilidade da fala dos participantes foi avaliada por dois julgadores sem experiência com deficientes auditivos, usando o método de transcrição e a escala de inteligibilidade de 5 pontos. Após 10 anos de experiência com o IC, 53 participantes (86,9%) alcançaram habilidade de reconhecimento auditivo em conjunto aberto. Os resultados médios obtidos na lista de palavras dissílabas foram de 49,4%; teste Hint adaptativo, a média dos resultados no silêncio foi igual a 54,7dB e, no ruído, 10,7 dB e; os valores médios de porcentagem nas sentenças Hint no silêncio 54% e no ruído, 33,3%. Quanto à inteligibilidade de fala dos participantes, a média de acertos no método de transcrição foi igual a 76,2%. Na escala de inteligibilidade, a pontuação média correspondeu a 3,3 pontos. Melhores desempenhos de audição no silêncio e no ruído foram correlacionados ao menor tempo de privação sensorial auditiva. Foi observada correlação entre o tipo de dispositivo utilizado e: o desempenho de audição no ruído e o desempenho de inteligibilidade da fala. Usuários do dispositivo Nucleus 24 e Med-El apresentaram melhor desempenho de audição e de inteligibilidade de fala do que os usuários Nucleus 22. Mais de 10 anos após a cirurgia de IC, 82% das crianças implantadas com as primeiras gerações do dispositivo eletrônico desenvolveram habilidade de reconhecimento auditivo no ruído e 90,1% alcançaram fala inteligível. O desempenho de audição e de inteligibilidade de fala dos participantes foi influenciado pelo tempo de privação sensorial auditiva e pelo tipo de dispositivo eletrônico. Considerando os critérios contemporâneos de indicação cirúrgica em associação as novas estratégias de codificação de fala disponíveis nos dispositivos eletrônicos da atualidade, resultados promissores são esperados para a nova geração de crianças submetidas ao IC / The communication skills of prelingually deafened children, underwent cochlear implant (CI) surgery, develop over the years of device use. The aim of this work was to study the performance achieved by teenagers and young adults with at least ten years of IC experience with regard to speech perception and speech intelligibility and, considering the type of hearing loss, duration of deafness, and type of device. Participated of this study, 61 teenagers and young adults prelingually deafened, who received different types of CI, on average at 3 years and 10 months of age. Recognition of two-syllable word list, test Hint and recognition of Hint sentence in quiet and noise were the procedures used to evaluate the hearing performance. The speech intelligibility of the participants was evaluated by two judges, using the writedown intelligibility method and a 5-points intelligibility rating-scale. After 10 years of experience with CI, 53 participants (86,9%) achieved open-set speech recognition. The average results obtained in the two-syllable word list were 49, 4%; in the test Hint in quiet, the average results were 54,7 dB in quiet and 10,7 dB in noise and; the mean percentage of Hint sentences in quiet was 54% and in noise, 33,3%. Regarding the speech intelligibility of the participants, the average write-down intelligibility score was 76,2% and the average rating-scale intelligibility score was 3,3 points. Better speech performances in quiet and in noise were correlated with shorter duration of deafness. Correlation was found between the type of device and: the speech perception in noise and the speech intelligibility. Nucleus 24 and Med-El device users performed better than Nucleus 22 users with regard to speech perception in noise and speech intelligibility. More than 10 years after the CI surgery, 82% of children implanted with the first generation of the electronic device developed speech recognition in noise and 90,1% achieved intelligible speech. Speech perception and speech intelligibility of the participants, both were influenced by duration of deafness and type of electronic device. Considering the contemporary criteria of surgical indication in association with the new speech coding strategies available, promising results were expected for the new generation of children underwent to CI

In this study, the immediate and short term (three months) effects of conservation burning have been investigated in coniferous forests in southeastern Sweden. Five tree species were investigated Picea abies (Norway spruce), Pinus sylvestris (Scots pine), Populus tremula (aspen), Betula pendula (silver birch) and Betula pubescens (downy birch), as well as ground vegetation of mosses, dwarf shrubs and ground lichens. Burning increased the proportion of live deciduous tree shoots from 51 % to 81 % and the live tree shoot size distribution of four tree species was significantly changed by fire. Fire affected the tree species differently. Three months after burning deciduous tree species exhibited strong sprouting, while P. sylvestris had established many seedlings, significantly increasing its share of the tree stand. P. abies lacked any visible positive response to burning and its number of live shoots decreased by 83 %. Mineral soil was exposed on only the moss vegetation and covered just 4 % of the studied plot area. The initial vegetation response to fire was negative, but significant dwarf shrub recovery was detected three months after burning.

Made available in DSpace on 2014-12-17T14:46:55Z (GMT). No. of bitstreams: 1 MagnaMPS_DISSERT.pdf: 1336445 bytes, checksum: 2998e1c0551bf591c5ce1acc115c4190 (MD5) Previous issue date: 2011-11-18 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / A quantitative, descriptive, cross-sectional and retrospective study, using technical procedures of document consultation from secondary sources and health household survey with application form for face to face inter views, with the assent n?.039/2011 from the Ethics Committee of the Federal University of Rio Grande do Norte. The aim of this study was to analyze the cervix cancer control in the area47 of the Health Family Centre Nova Natal II. The cancer cervix is the second most common cancer among women worldwide. In Brazil screening for early detection and treatment of disease has been poorly done and follow-up to reduce mortality has not been executed. From a total of1170women belonging to area 47, who under went screening by the Pap test in the period from 2005 to 2010,was elected a sample of 38 women with positive cervical changes, over 18 years old. The calculation of frequency analysis of socio demographic and clinical and epidemiological selected variables with the results of cervical changes, using the X2 test and taking as significance level of p<0.05 was not statistically significant. The predominant age range was 25 to 64 years (68.9%), most no white women (60.5%), predominantly with primary education (57.9%), most married (68.4%) and housewives (68.4%) with early age of sexual activity (86.8%), the minority smokers (13.2%), with a sexual partner (36.8%). At the time of interview, 42.1% of the women voiced complaint of discharge, while only 2.6% reported bleeding. In relation to the occurrence of STDs (including HPV), 10.5% of women reported being a carrier. The use of oral contraceptives was 32.3% of women, from 2 to 4 years (44.4%). The result of the last screening test performed, showed prevalence of immature squamous metaplasia (55.3%), followed by intraepithelial low- grade lesion (including the cytopathologic HPV effect and cervical intra epithelial neoplasia grade I) (31.6%); intraepithelial high-grade lesion (including cervical intraepithelial neoplasia grade II and III) (7.9%), atypical squamous non neoplastic cells (5.3%). There was no squamous cell carcinoma and adenocarcinoma. Most women received information about the action that should be done after the last screening test result (55.3%), but how to perform follow, most women did not report having done so (55.3%). The follow-up group of women studied, with varying degrees of cervical abnormalities, should only be completed with the discharge by cure, established inconsecutive negative cytology, a goal that is not being achieved in the area 47 of the Health Family Centre of Nova Natal II / Estudo quantitativo realizado por meio de pesquisa descritiva, transversal e retrospectiva, utilizando procedimentos t?cnicos de consulta documental a fontes secund?rias e inqu?rito domiciliar com aplica??o de formul?rio de entrevistas face a face, ap?s parecer favor?vel n? 039/2011 do Comit? de ?tica em Pesquisa da Universidade Federal do Rio Grande do Norte. O objetivo dessa pesquisa foi analisar a resolutividade do controle da neoplasia maligna do colo de ?tero na ?rea 47 da Unidade de Sa?de da Fam?lia Nova Natal II. A neoplasia maligna do colo de ?tero ? o segundo tipo de c?ncer mais frequente entre as mulheres no mundo. No Brasil o rastreamento para detec??o e tratamento precoces da doen?a tem sido efetuado precariamente e o seguimento, para reduzir a mortalidade, n?o tem sido executado. De um total de 1170 mulheres pertencentes ? ?rea 47, que se submeteram a rastreamento por meio do exame de Papanicolau, no per?odo de 2005 a 2010, elegeu-se uma amostra de 38 mulheres com resultado positivo de altera??es cervicais, maiores de 18 anos. A an?lise do c?lculo da frequ?ncia de vari?veis sociodemogr?ficas e cl?nico-epidemiol?gicas selecionadas com os resultados das altera??es cervicais, utilizando-se o teste de X2 e adotando como n?vel de signific?ncia p<0,05 n?o mostrou signific?ncia estat?stica. A faixa et?ria predominante foi de 25 a 64 anos (68,9%); a maioria parda (60,5%); com escolaridade predominante at? o ensino fundamental (57,9%); a maioria casada ou em conviv?ncia marital (68,4%) e donas de casa (68,4%); com in?cio precoce da atividade sexual (86,8%), a minoria fumante (13,2%), com um parceiro sexual (36,8%). No momento da entrevista, 42,1% das mulheres verbalizou queixa de corrimento, enquanto apenas 2,6% referiu sangramento. Em rela??o ? ocorr?ncia de DSTs (inclusive HPV), 10,5% das mulheres declarou ser portadora. Verbalizaram o uso de contraceptivos orais, 32,3% das mulheres, por 2 a 4 anos (44,4%). Quanto ao resultado do ?ltimo exame preventivo realizado, prevaleceu a metaplasia escamosa imatura (55,3%), seguido de les?o intraepitelial de baixo grau (compreendendo efeito citopatol?gico pelo HPV e neoplasia intra-epitelial cervical grau I) (31,6%); les?o intra-epitelial de alto grau (compreendendo neoplasias intra-epiteliais cervicais de grau II e III) (7,9%); c?lulas at?picas escamosas de significado indeterminado, possivelmente n?o neopl?sicas, (5,3%). N?o foi observado carcinoma de c?lulas escamosas e adenocarcinoma. A maioria das mulheres recebeu informa??es sobre o seguimento que deveria ser realizado ap?s o resultado do ?ltimo exame preventivo (55,3%), mas, quanto a realizar o seguimento, a maior parte das mulheres n?o referiu t?-lo feito (55,3%). O seguimento do grupo de mulheres analisadas, com diferentes graus de altera??es cervicais, somente deveria ser finalizado com a alta por cura, estabelecido em citologias consecutivas negativas, meta que n?o est? sendo atingida na ?rea 47 da Unidade de Sa?de da Fam?lia Nova Natal II

Indiana University-Purdue University Indianapolis (IUPUI) / Epidemiological studies suggest that depression may be an independent risk factor for cardiovascular disease (CVD). Although several possible mediators of this association have been proposed, the precise mechanisms are yet unknown. Accordingly, we examined periodontal disease as a novel mediator of the depression-CVD association, given its separate links with both depression and CVD. Data from the National Health and Nutrition Examination Survey (NHANES) I and its Epidemiologic Follow-up Study (NHEFS) were analyzed. Participants were 3,346 individuals aged 25-74 years free of CVD at baseline (53% female, 16% non-white). Depression was assessed by the, depressed mood subscale of the General Well-Being Schedule Based on the Russell Periodontal Index, periodontal disease (43%) was defined as the presence of four or more periodontal pockets identified by a licensed dentist during an examination. The primary outcome was incident CVD (n=727, 22%), defined as nonfatal or fatal coronary artery disease or cerebrovascular disease, identified during the follow-up period by interviews and death certificate records. All analyses were adjusted for demographic and cardiovascular risk factors. Logistic regression analyses revealed no association between the GWBS depressed mood score and periodontal disease (OR=1.05, 95% CI: 0.96-1.14, p=.24). Cox proportional hazard models revealed that both periodontal disease (HR=1.24, 95% CI: 1.06-1.46, p=.009) and depressed mood (HR=1.08, 95% CI: 1.01-1.17, p=.03) were significant predictors of incident CVD. However, Sobel analyses found that periodontal disease was not a partial mediator of the depressed mood-incident CVD association (t=1.01, p=.31). Overall, these mediation results suggest that (a) both periodontal disease and depressed mood are independent predictors of incident CVD and that (b) the effect of depressive symptoms on incident CVD is not mediated by periodontal disease.