The aim of this thesis is to analyze which potential users and requirements there are on a quality assurance tool to facilitate improving quality in technical documentation. The issues for this thesis to answer are to (1) define potential user groups and their requirements, (2) explore what ways introducing a quality assurance tool could facilitate quality in technical documentation, and (3) explore what challenges needs to be considered when integrating it into the workflow. The empirical research carried out at Saab Support & Services AB in Linköping in the form of semi-structured interviews constitutes the core case study evidence. Three personas are constructed on the basis of collected and analyzed data, corresponding for the potential user groups. For each persona, data requirements, as well as functional requirements, are generated through scenarios that are constructed to constitute for the possible contexts that the personas could find themselves in using this quality assurance tool. Further, this study explores some challenges that must be solved in order to satisfy the requirements of the potential users: to find a place in the workflow that suits the requirements from all perspectives. It shows important considerations to have in mind while integrating a quality assurance tool into the process of producing technical documentation, and opens up for questions of future studies within the integration of quality assurance tools into complex contexts.

No description available.

Indiana University-Purdue University Indianapolis (IUPUI) / Lentiviral vector mediated gene therapy has made great strides in recent years with several successful clinical trials. However, adverse events encountered with some early trials have highlighted the necessity to improve upon its safety. Improvements can range from early steps in vector production to evaluation of insertion sites post-transduction. We have evaluated an FDA approved DNase for removal of residual plasmid DNA during vector production, developed novel non-integrating lentiviral vectors and employed modified insertion site analysis post-transduction to improve the safety of lentiviral vector mediated gene therapy. To prevent the exposure of gene therapy patients to HIV-1 DNA it is essential to remove residual plasmid DNA during vector production. We evaluated a recombinant human DNase which has been FDA approved for use in patients as an alternative to a bacterially derived DNase. Our results indicate this DNase is an effective alternative with a potentially safer profile for use in patients. The ability of lentiviral vectors to stably integrate their genome into a host cell’s DNA can have negative side-effects due to the risk of insertional mutagenesis. Non-integrating lentiviral vectors have been developed to alleviate this risk in applications where integration is not necessary. However, a low frequency of illegitimate integration persists when using these vectors. We have developed a novel non-integrating vector mutation and evaluated the efficacy of combining it with other mutations for reducing the frequency of illegitimate integration. We demonstrate that combining mutations that inhibit integration can further reduce the frequency of illegitimate integration. Several methodologies have been developed for evaluating the insertion sites of normal integrating lentiviral vectors. Illegitimate integration by non-integrating vectors demonstrates mechanisms which result in insertions and/or deletions at the vector-genome junction. Current methods lack the sensitivity to account for these variables in a high-throughput manner. We have adapted modifications to current methods to improve the capture of these variable insertion sites for analysis. The results of these studies improve the safety of lentiviral vector mediated gene therapy by improving the purity of the vector product, providing a safer vector for non-integrase mediated applications, and allowing more sensitive analysis of insertion sites post-transduction.

This mixed-methods dissertation used an explanatory sequential design to examine art and mathematics preservice teachers' perceptions and attitudes towards integrating art and mathematics (IAM) after an IAM workshop. The conceptual framework of this study has its basis in three theoretical sources: constructivism, multiple intelligence theory, and semiotics. Each of these sources provides a conceptual lens to examine art integration in the curriculum and the teacher's role in facilitating this instructional process. Participants of this study included two sub-groups at a large university in Saudi Arabia. The first sub-group was preservice teachers of art education. The second sub-group was preservice teachers of mathematics. Quantitative and qualitative results indicated that the IAM workshop had positive impacts on art and mathematics preservice teachers' attitudes and perceptions of IAM. Participants attributed more value to art, were more willing to apply IAM, and felt that there was less barriers for applying IAM. The study also indicated differences between art and mathematics preservice teachers' attitudes towards IAM. The differences were due more to art value than willingness or barriers. After the IAM workshop, mathematics preservice teachers put more emphasis on the importance of art to mathematics, especially with respect to making mathematics a more enjoyable subject.

It is proved that cloud computing has many benefits, and cloud services with flexible licensing model and cost saving features bring opportunities to enterprise's IT operations. Conventional ERP system, an important component of enterprises, is impacted by on-demand cloud services also. Integrating conventional ERP system with cloud services becomes a trend because it brings new processing capabilities without introducing significant changes to existing system. But previous studies about integrating ERP and cloud usually focused on SaaS (Software as a Service). PaaS (Platform as a Service) and IaaS (Infrastructure as a Service) are not discussed much. People sometimes even confuse cloud service with SaaS. Therefore, the objective of this paper is to present a framework that can describe respective implications of integrating ERP with three types of cloud services: SaaS, PaaS and IaaS. Qualitative methods such as systematic literature review and interviews are adopted to execute the research, so data collected through different sources can complement each other in order to support presenting the framework of integrating conventional ERP system and cloud services. The integration at SaaS level is for achieving immediate business value and productivity enhancement. At PaaS level the objective of integration is to enhance software development life cycle management. And the main integrating intent at IaaS level is to enable scalability and reliability of hardware resources without changing existing IT infrastructure. Furthermore, challenges and opportunities for integrating ERP with different cloud services are studied and motivation is derived from analyzing. Finally the key points are arranged in the presented framework of integration between conventional ERP systems and cloud services.

Hur upplever och integrerar pedagoger, i grundskolan, matematik i tematiskt arbete. För att undersöka detta genomfördes åtta intervjuer med pedagoger, på skolor i Sverige, som profilerar sig med tematiskt arbete på deras hemsida. Metoden som valdes för att genomföra undersökningen var kvalitativa intervjuer. Resultatet visade att matematik är det ämne som pedagoger är sämst på att integrera. Det visades sig även att pedagoger upplever matematik som det svåraste ämne att integrera i sin tematiska undervisning, vilket även forskning visat.

This research investigates the current state and ability of homestation training infrastructure (TADSS, networks, and facilities) and framework for training (scenarios, databases, and training support packages) to support a Live Virtual Constructive – Integrating Architecture (LVC-IA) delivered Integrated Training Environment (ITE). As combat operations in Central and Southwest Asia come to a close the Army is faced with extreme post-conflict budget cuts and force reductions. Continued evolution of Army training methodology is required to overcome limited resources and maintain force readiness in the anticipated “era of persistent conflict”. A LVC-IA delivered ITE promises to be the next step in the evolution of training. Interoperation of live, virtual, and constructive simulations in a persistent and consistent manner can collectively train brigade and below units on combined arms tasks in a resource constrained homestation environment. However, LVC-IA cannot act alone in establishing the ITE. Prior to the fielding of LVC-IA, local installations must already possess a training infrastructure that optimizes training resources as well as a framework for training that meets Operational Adaptability training requirements. To measure the perceived state and ability of homestation training infrastructure and framework for training to support a LVC-IA delivered ITE, a survey was conducted of homestation training community members at the 18 Army installations scheduled for LVC-IA fielding. Additionally, perceptions regarding the role of LVC-IA in establishing the ITE and emerging resources, useful in the development of local framework for training were sought. Findings, conclusions, limitations, lessons learned, and recommendations for future research are presented.

Strong educators always look for different ways to excite and enthrall their students in the curriculum. The field of science education often loses student interest due to the complexities and vocabulary found in the scientific realm. Incorporating music into the classroom has shown positive results as a way to integrate student learning and a different way of facilitating students in the learning process (Brewer, 1992; Davies, 200). Resources for implementing the integration of music and science exist throughout the Internet in a variety of mediums. This study looks at the availability of said resources and the concepts they cover, for what students they are intended for, how are they intended to be used and the level of accuracy they maintain. Those resources upholding the accuracy desired for use in the classroom were then compiled onto one webpage for use by elementary science educators. The webpage is open and free to the public and may be shared.

No description available.

<p>Single junction silicon photovoltaic cells (SJSPVCs) are unable to transform all the energy in the solar spectrum into electricity, due to the broad nature of the solar spectrum and the limits imposed by a single bandgap. Furthermore, high surface recombination velocity reduces the SJSPVC external quantum efficiency response, particularly to ultraviolet photons. It is the goal of spectral engineering to optimize the light that is incident on the cell, by down-shifting high energy photons to lower energies, for example, to improve the performance of photovoltaic cells.</p> <p>This thesis represents a study into the luminescence of ion implanted films, involving silicon nanocrystals (Si-NCs) and rare-earth ions in fused silica or silicon nitride. Quantum efficiency measurements taken with an integrating sphere were used to characterize some of the samples. Other photoluminescence (PL) characterization work was carried out with a single-wavelength laser and a collection lens normal to the sample. Variable angle spectroscopic ellipsometry (VASE) was used to estimate the optical constants of the implanted films. In secondary work, Rutherford backscattering spectrometry, time-dependent PL, infrared-PL measurements, and electrical conductivity measurements were used to characterize select samples.</p> <p>It was found that the conversion efficiency of Si-NCs in fused silica was about 1% – too low to be useful according to modeled results. However, considerable variation in the peak wavelength of the Si-NC PL was obtained, depending on the peak concentration of implanted silicon. Si-NC-type PL was also produced by low-energy implantation of oxygen into a Czochralski silicon wafer.</p> <p>Oxygen was also implanted into films of cerium-doped high-purity silicon nitride, and it was shown that the photoluminescence from these films is largely dependent on the level of oxygen doping. The internal conversion efficiency of a cerium-doped fused silica sample was found to approach 20%, which indicates that this is a promising avenue for future research.</p> <p>Finally, energy transfer was demonstrated between Si-NCs and erbium ions. The lifetime of the erbium PL appears to increase with increasing implanted silicon fluence.</p> / Master of Applied Science (MASc)