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Playing Music as a Nursing Intervention to Reduce Distress in Neonatal and Pediatric Acute Care Patients: A Literature ReviewÖzoğlu, Seren E 01 January 2021 (has links)
Pediatric and neonatal patients are especially vulnerable to suffering from distress. This literature review identifies research which applies passive music listening to distressed neonatal and pediatric acute care patients. Databases searched to find relevant studies include CINAHL plus with full text, MEDLINE, Alt HealthWatch, APA PsycArticles, and APA PsycInfo from EBSCOhost. Six studies were identified to meet search criteria. The studies that supported music listening with the neonatal and pediatric populations had a positive effect in reducing distress levels. Additional research is warranted to further validate these findings. Music listening with neonatal and pediatric patients is a simple, cost-effective intervention that nurses can implement at the bedside.
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Facilitation of Enviromental Factors to Reduce Sound Decibels in the Neonatal Intensive Care Unit: A Literature ReviewHanlon, Cassandra 01 January 2021 (has links)
This literature review investigates nursing interventions to reduce decibel levels in the neonatal intensive care unit (NICU). The secondary purpose of this review was to evaluate if the interventions to reduce noise in the NICU had different outcomes for normal weight premature infants and infants afflicted with neonatal abstinence syndrome. The data bases for completing this review were Google Scholar, the Cumulative Index to Nursing and Allied Health Literature (CINAHL Plus), PubMed, and Elton B. Stephens Co. (EBSCO). The key search words included ‘NICU and decibels', ‘reducing decibels', ‘neonatal abstinence syndrome' ‘decibels', ‘preterm infants' and 'normal weight preterm infant*'. The inclusion criteria were research articles from 2008 to 2020, articles with a focus on normal weight premature infants and normal weight infants determined to be addicted to a recreational or illicit substance after birth. The results yielded 8 articles meeting inclusion criteria and screened for relevance to the topic. Data indicated there is a need for further research into using multiple interventions. One intervention alone can currently not reduce decibel levels to the recommended level.
Conclusions: Currently the research states private rooms reduce decibel levels the most out of the other intervention listed in the study. Further research with long-term neuro-cognitive data collection over a longer period of time and larger sample sizes is needed to evaluate the use of interventions to reduce high level, decibel noise found in the NICU.
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Prolongerad neonatal ikterus iRegion Örebro länFältsjö, Klara January 2021 (has links)
Inledning: Prolongerad neonatal ikterus defineras som kvarstående ikterus vid 14 dagarsålder hos fullgångna barn. Den vanligaste orsaken till detta, hos ett för övrigt friskt barn, ärbröstmjölksinducerad ikterus men prolongerad ikterus kan också vara tecken på allvarligsjukdom såsom kolestas. I Region Örebro län fanns en rutin för utredning av barn medprolongerad ikterus som användes under perioden 21 september 2020, till och med 12 februari2021. Den byggde på att barnavårdscentralen skickade remiss för provtagning som sedangenomfördes på barnkliniken, universitetssjukhuset Örebro (USÖ). Syfte: Syftet med studien var att utvärdera Region Örebro läns regionala rutin för utredningav prolongerad neonatal ikterus, som tillämpades under perioden 21 september 2020 till ochmed 12 februari 2021. Metod: Studiepopulationen bestod av 33 patienter med prolongerad neonatal ikterus sominkommit till barnkliniken för provtagning enligt rutinen under studieperioden 21 september2020 till och med 12 februari 2021. En prospektiv kvalitetssäkrande journalgranskninggenomfördes på barnkliniken USÖ. Resultat: Incidensen av prolongerad neonatal ikterus i Region Örebro län beräknades till3,4% (95% KI, 2,3–4,5). Ett barn med kolestas konstaterades. Ingen remiss innehöll allakriterier som fanns beskrivna i rutinen och ingen skillnad i remisskvalité beroende påprofession kunde fastställas. De flesta barn inkom för provtagning vid cirka tre veckors ålderoch fem patienter uteblev från provtagning. Slutsats: Studien visade att Region Örebro läns rutin för prolongerad neonatal ikterus, underperioden som rutinen tillämpades, till stor del var resurskrävande och följsamheten till rutinenvar bristfällig, vilket kunde leda till patientsäkerhetsrisker och ineffektiv vård. För attförbättra detta föreslår vi skapandet av en ny rutin där hänsyn tas till de risker som vår studiehar identifierat.
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Type II Error and Evaluation of Kangaroo Care in Tertiary Neonatal UnitsEvans, Lauren B., Glenn, L. Lee 01 January 2015 (has links)
No description available.
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Clinical Practice Guidelines for the Management of Neonatal Abstinence Syndrome: A Systematic Review and EvaluationFigeys, Christine 05 December 2023 (has links)
Neonatal abstinence syndrome (NAS) refers to the withdrawal symptoms experienced when an infant has been exposed to certain substances (e.g., opioids) in-utero, resulting in health challenges for infants. Previous studies have reported substantial variations in the clinical management of NAS, suggesting that some infants may not be receiving optimal care. High-quality clinical practice guidelines are crucial to support optimal patient outcomes and standardize care. In response, I conducted a systematic review and quality appraisal of available NAS guidelines and recommendations using the AGREE-II and AGREE-REX tools. I also developed and piloted a tool to measure family-centred care in guidelines. Most guidelines received low-quality appraisal scores on the AGREE-II and the AGREE-REX appraisals (16/20 and 10/20, respectively) and have conflicting pharmacological recommendations. Findings will improve clinicians’ awareness of the variation in the quality of guidelines and assist them to make care decisions that are from the best available evidence and family-centred.
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Nutritional Intake and Weight Gain in Infants with Neonatal Abstinence Syndrome: A Literature ReviewKubisch, Kailey A 01 January 2019 (has links)
Neonatal abstinence syndrome (NAS) in infants presents unique challenges in feeding and weight gain. The unpredictable clinical manifestations associated with the newborns withdrawal from exposure to drugs in utero can lead to costly delays in transition of the infant out of the Neonatal Intensive Care Unit (NICU).The purpose of this review of literature was to explore feeding positions and nutritional intake with the greatest impact on weight gain in infants with neonatal abstinence syndrome (NAS) following delivery. The secondary purpose was to compare the clinical manifestations of infants with NAS that influence nutritional intake and their relationship to length of time and cost of stay in the NICU. A review of literature was performed using multiple databases. Articles focusing on feeding position and nutrition intake were identified for interventions to effectively promote weight gain, while reducing clinical manifestations common in infants with NAS. Articles exploring improved feeding and weight gain in infants with NAS and reduced length of stay in the NICU were also synthesized for cost reductions to the facility. Results from 12 studies comparing various feeding positions that optimized nutrition, and reduced negative clinical manifestations in infants with NAS were synthesized for content relevant to the research questions. Results suggest a relationship between placing infants in the c-position, and side-lying position to reduce sensory stimulation, with reducing clinical manifestations for infants actively experiencing withdrawal symptoms from NAS. Providing chin and cheek support as needed, decreasing eye contact during feeding periods, and providing darker quiet environments all play an important role in allowing infants with NAS to optimize their weight gain. As previously stated, to manage nutritional intake and optimize weight gain, reduction of clinical manifestations through pharmacological and non-pharmacological interventions must be actively incorporated into the infants' plan of care.
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Bortom kuvösen : föräldrars erfarenheter av familjecentrerad omvårdnad inom neonatalvården / Beyond the incubator : parents' experiences of family-centered care in neonatal unitsRapaport Ronthén, Josefina, Lindell Harrysson, Lovisa January 2024 (has links)
Bakgrund Under de senaste årtiondena har synen på familjen genomgått en betydande förändring, där traditionella normer gradvis har ersatts av en mångfald av familjekonstellationer. Samtidigt har betydelsen av familjecentrerad omvårdnad ökat inom hälso- och sjukvården, där sjuksköterskor spelar en central roll i att integrera familjens perspektiv och erfarenheter i vårdprocessen. Särskilt inom neonatalvården där föräldrar och spädbarn står inför unika utmaningar vilket gör familjecentrerad omvårdnad särskilt relevant inom dessa verksamheter. Syfte Syftet med denna litteraturstudie var att belysa föräldrars erfarenheter av familjecentrerad omvårdnad inom neonatalvården. Metod En icke-systematisk litteraturöversikt genomfördes för att sammanställa relevant forskning inom ämnet. Totalt granskades 12 vetenskapliga artiklar som omfattade flera länder, inklusive England, Nederländerna, Italien, Japan, Danmark, Nya Zeeland, Indien och USA. Artiklarna analyserades med hjälp av integrerad analys. Resultat Resultatet delades in i två huvudkategorier: Erfarenheter av delaktighet samt Erfarenheter av stöd. Det framkom att föräldrar upplevde ökad känsla av kontroll och trygghet när de involverades i vården och de uppskattade stöd från vårdpersonal. Uppmuntran och handledning från sjuksköterskor bidrog till föräldrarnas självförtroende och förmåga att vårda sina spädbarn. Positiva interaktioner och hud-mot-hud betonades som betydelsefulla för anknytningen till spädbarnet. Även om utmaningar som bristande kommunikation och vårdmiljöns begränsningar identifierades, indikerade resultaten övergripande att familjecentrerad omvårdnad kan stärka föräldrarnas delaktighet och välbefinnande. Slutsats Föräldrars erfarenheter av att känna delaktighet och stöttning i vårdprocessen verkar vara avgörande för deras välbefinnande och upplevelse av vården. Detta understryker betydelsen av att främja och stödja föräldrars aktiva engagemang inom vårdsammanhang, där sjuksköterskor spelar en central roll genom att aktivt involvera och stödja familjen. / Background Over recent decades, the perception of family has undergone a significant change, with traditional norms gradually being replaced by a diversity of family constellations. Concurrently, the importance of family-centered care has increased within healthcare, with nurses playing a central role in integrating the family's perspective and experiences into the care process. Particularly in neonatal care, where parents and infants face unique challenges, making family-centered care especially pertinent in these settings. Aim The aim of this literature review was to highlight parents' experiences of family-centered care in neonatal healthcare. Method A non-systematic literature review was conducted to compile relevant research on the topic. A total of 12 scientific articles were reviewed, encompassing several countries, including England, the Netherlands, Italy, Japan, Denmark, New Zealand, India and the USA. The articles were analyzed using integrated analysis. Results Findings were divided into two main categories: Experiences of involvement and Experiences of support. It was found that parents experienced increased sense of control and security when involved in the care and they appreciated support from nursing staff. Encouragement and guidance from nurses contributed to parents' confidence and ability to care for their infants. Positive interactions and skin-to-skin were emphasized as significant for bonding with the infant. Although challenges such as poor communication and limitations in the healthcare environment were identified, the results overall indicated that family-centered care can enhance parents' involvement and well-being. Conclusions Parents' experiences of feeling involved and supported in the care process seem to be crucial for their well-being and experience of care. This emphasizes the importance of promoting and supporting parents' active engagement in healthcare contexts, where nurses play a central role by actively involving and supporting the family.
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Potencial evocado auditivo de tronco encefálico e de estado estável com estímulo clique na triagem auditiva em lactentesCea, Jenny Andrea Agurto 19 February 2009 (has links)
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Previous issue date: 2009-02-19 / Conselho Nacional de Desenvolvimento Científico e Tecnológico / Introduction Conventional (ABR) or automatic (AABR) auditory brain responses is an electrophysiological method used in auditory screening, mainly in newborns with hearing loss risk indicators. Studies indicate that click stimulus used in auditory steady state response (ASSR) can quickly detect the presence of response at low intensities as well as can simultaneously stimulate both ears. The procedure could then be useful in newborn auditory screening (NAS). Objective To describe and to compare the results of pass and refer as well as the duration of the hearing screening in infants by the use of ABR, AABR and ASSR with click stimulus techniques at 30 and 35dBHL intensities. Methods Once referred from public hospitals for hearing screening, 30 infants with hearing loss risk indicators aging from 10 to 97 days were evaluated. ASSR and ABR techniques were performed at 30 and 35dBHL intensities. The AABR one was held at 35dBHL. In ASSR 11 infants underwent binaural stimulation and 19 infants, the mononaural one. Those who failed could be reevaluated. The duration of each of the techniques was also analysed. Results The AABR technique showed that 28 (93.3%) infants passed in both ears and 2 (6.7%) had bilaterally failed. The meantime of test duration was nearly 1.8 minutes for right ear(RE) and 2.1 minutes for left Ear (LE). For ABR at 30dBHL , 27 (90%) subjects passed in both ears, 2 (6.7%) failed bilaterally and only 1 (3.3%) failed unilaterally. At 35dBHL, 26 (86.7%) passed in both ears, 2 (6.7%) failed unilaterally and 2 (6.7%) failed bilaterally. The meantime of test duration was nearly 2.4 minutes for each ear, at both intensities. For ASSR at 30dBHL, 26 (86.6%) infants passed in both ears and 4 (13.3%) failed unilaterally. The average test duration in monoaural evaluation was nearly 2.3 minutes in RE and 2.5 minutes in LE. In binaural evaluation the average duration was 3.1 minutes. At 35dBHL, 25 (83.3%) infants passed in both ears and 5 (16.7%) failed unilaterally. For RE evaluation the average duration was 2.2 minutes and for LE it was 2.1 minutes. When performed the binaural test, the average duration was 3.7 minutes. At 30 dBHL, results suggest agreement for both tests. As to the duration, no significant difference was detected between ABR and ASSR values. At 35dBHL most individuals showed concordant results when compared in twos. In duration assessment the lowest mean and median values were observed in AABR test and the highest in ASSR binaural. Most subjects who passed in ASSR were evaluated only once. There was no association between the results and gestational age at both intensities. Conclusion There was a clear agreement between ABR and ASSR results at 30dBHL; AABR and ABR techniques showed strong concordant results at 35dBHL and no significant differences were detected among the three techniques as to the test duration. Additional investigations on ASSR in NAS are needed so that the technique can be improvingly adjusted / Introdução O potencial evocado auditivo de tronco encefálico (PEATE) convencional ou automático é um método eletrofisiológico aplicado na triagem auditiva, principalmente em neonatos com indicadores de risco para perda auditiva (IRPA). Estudos apontam que o estímulo clique utilizado no potencial evocado auditivo de estado estável (PEAEE) detecta de forma rápida a presença de resposta nas intensidades fracas, podendo estimular ambas as orelhas simultaneamente. Trata-se de um procedimento que pode ser útil na triagem auditiva neonatal (TAN). Objetivo Descrever e comparar os resultados de passa e falha, assim como a duração da triagem auditiva em lactentes com a utilização do PEATE, PEATE-A e PEAEE - clique nas intensidades de 30 e 35 dBNA. Método Foram avaliados 30 lactentes com IRPA encaminhados de hospitais públicos para realizar a triagem auditiva. As técnicas realizadas foram PEATE e PEAEE- clique nas intensidades de 30 e 35 dB NA. O PEATE-A foi realizado em 35dBNA. No PEAEE - clique onze lactentes realizaram a estimulação binaural e dezenove, monoaural. Aqueles que falhavam poderiam ser avaliados mais de uma vez. Foi realizada a análise da duração de cada técnica. Resultados Foram avaliados 30 lactentes com idade entre 10 e 97 dias. Os resultados encontrados no PEATE-A foram: 28(93,3%) lactentes passaram em ambas as orelhas e dois (6,7%) falharam bilateralmente. O tempo médio de duração do teste foi de, aproximadamente, 1.8 min. para a OD e 2.1 min. para a OE. No PEATE na intensidade de 30dBNA 27 lactentes (90%) passaram em ambas as orelhas; dois lactentes (6,7%) falharam bilateralmente e apenas um (3,3%) falhou unilateralmente. Na intensidade de 35dBNA 26 (86,7%) passaram em ambas as orelhas; dois (6,7%) falharam unilateralmente e dois (6,7%) falharam bilateralmente. O tempo médio de duração foi de, aproximadamente, 2.4 min. para cada orelha nas duas intensidades. No PEAEE - clique em 30dBNA 26 (86,6%) passaram em ambas as orelhas e quatro (13,3%) falharam unilateralmente. O tempo médio de duração do teste na avaliação monoaural foi de, aproximadamente, 2.3 min. na OD e 2.5 min. na OE. Na avaliação binaural o tempo médio foi de 3.1 min. Em 35dBNA os resultados encontrados foram: 25 (83,3%) lactentes passaram em ambas as orelhas; cinco (16,7%) falharam unilateralmente. Para a avaliação na OD o tempo médio foi de 2.2 min., e para a OE, de 2.1 min. Quando realizado o teste de forma binaural, o tempo foi de 3.7 min. Em 30dBNA os resultados sugerem concordância nos dois testes. Em relação ao tempo médio não foi detectada diferença significativa entre o PEATE e PEAEE - clique. Na intensidade de 35dBNA, na maioria dos indivíduos, ocorreu concordância de resultado nos testes quando comparados dois a dois. Na análise da duração os menores valores médios e medianos foram observados no PEATE-A, e os maiores no PEAEE - clique binaural. A maioria dos sujeitos que passaram no PEAEE - clique realizou a avaliação apenas uma vez. Não houve associação entre os resultados e a idade gestacional nas duas intensidades. Conclusão Houve concordância nos resultados em 30 dBNA para PEATE e PEAEE - clique; o PEATE-A e o PEATE apresentaram forte concordância em seus resultados na intensidade de 35 dBNA; não houve diferença significativa em relação à análise de duração de tempo das três técnicas estudadas. São necessários mais estudos com PEAEE - clique na TAN para que possam ser realizados ajustes nessa técnica
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Acompanhantes de crianças hospitalizadas em unidade neonatal : preocupações e estratégias relacionadas à segurança do paciente / Hospitalized children's companions in neonatal unit : concerns and strategies related to patient safety / Compañeros de niños hospitalizados en una unidad neonatal : preocupaciones e estrategias relacionadas a la seguranza del pacienteRodrigues, Fernanda Araújo January 2016 (has links)
O cuidado em saúde não é isento de risco e danos ocorrem apesar da intenção dos profissionais de proporcionar benefícios. Na Unidade de Internação Neonatal, há distintas circunstâncias que permeiam os riscos deste grupo de pacientes. O objetivo desta pesquisa foi analisar como o acompanhante identifica preocupações e estratégias relacionadas à segurança da criança hospitalizada em uma unidade neonatal. Trata-se de um estudo de caso exploratório, com abordagem qualitativa, desenvolvido na Unidade de Internação Neonatal, do Hospital de Clínicas de Porto Alegre. A coleta de informações aconteceu entre junho e agosto de 2015, após a aprovação pelo Comitê de Ética (nº 1.094.423). Foram realizadas entrevistas com 23 participantes, os quais eram acompanhantes de crianças hospitalizadas. O software QSR NVivo versão 10.0 foi utilizado para o processamento e a organização das informações, as quais foram submetidas à análise de conteúdo do tipo temática. Identificou-se que 16 participantes mencionaram 95 referências relacionadas a categoria Preocupações com a Segurança do Paciente, como falta de controle no acesso, comunicação deficiente, risco de infecção e outros aspectos relacionados à dinâmica de trabalho. Ainda, foi possível detectar 196 referências relacionadas a categoria Estratégias para a Segurança do Paciente, sendo que todos os acompanhantes referiram pelo menos uma, como: prestação de serviço com excelência, realização de cuidado com amor, e manutenção de ambiente protegido. A importância da inclusão do acompanhante no processo de cuidar foi reafirmada no final do estudo, corroborando com o fato de o familiar analisar como a equipe de saúde assiste à criança, sendo considerado parceiro no tratamento. Salienta-se como principais contribuições do estudo o reconhecimento da presença do acompanhante e a responsabilidade a ele atribuída na hospitalização, especialmente em neonatologia; a possível qualificação da assistência à criança hospitalizada, a partir da adoção de condutas, pelos profissionais de saúde, em conformidade com as estratégias descritas pelos participantes; e, consequentemente, o desenvolvimento de uma cultura de segurança. / The health care is not exempted of risk, and damage occurs besides health professionals’ intention of goodness. In the Neonatal Unit, several circumstances permeate the risks of this group of patients. The objective of this research was to analyze how the companion identifies concerns and strategies related to the safety of a child hospitalized in a neonatal unit. This study is an exploratory case study, which has a qualitative approach, developed at the Neonatal Care Unit of Hospital de Clínicas de Porto Alegre. Data collection happened from June to August of 2015, after the Ethics Committee approval (nº 1.094.423). Interviews with 23 participants were performed, who were companions of hospitalized children. The software NVivo version 10.0 was used for the processing and organization of the information, which was submitted to thematic analysis of content. Sixteen participants mentioned 95 references related to the category Concerns with Patients Safety, like the lack of access control, deficient communication, risk of infection and other aspects related to work dynamics. Still, 196 references related to the category Strategies for Patient Safety were detected, and all companions reported at least one strategy, like the excellent service provided, assistance provided with love, and maintenance of a safe environment. The importance of companion’s inclusion in the process of care was reaffirmed at the end of the study, confirming the fact that the relative analyzes how the staff assists the child, being considered a copartner during the treatment. It is possible to accentuate as major contributions of the study the acknowledgement of the companion’s presence and the responsibility attributed to him/her during the hospitalization, especially in neonatology; the possible qualification of the assistance to the hospitalized child, from the adoption of conducts by health professionals, in conformity to the participants’ strategies; and, consequently, the development of a safety culture. / El cuidado en salud no es libre de riesgos, y daños ocurren a pesar de la intención de los profesionales de proporcionar beneficios. En la Unidad de Internación Neonatal, hay distintas circunstancias que permean los riesgos de este grupo de pacientes. El objetivo de esta pesquisa fue analizar como el compañero identifica preocupaciones y estrategias relacionadas a la seguranza del niño hospitalizado en una unidad neonatal. Este es un estudio de caso exploratorio, con abordaje cualitativa, desarrollado en la Unidad de Admisión Neonatal del Hospital de Clínicas de Porto Alegre. La recolecta de informaciones ocurrió entre junio a agosto de 2015, después de la aprobación del Comité de Ética (nº 1.094.423). Fueron realizadas entrevistas con 23 participantes, los cuales eran compañeros de niños hospitalizados. El Software QSR NVivo versión 10.0 fue utilizado para el procesamiento y la organización de las informaciones, las cuales fueron sometidas al análisis de contenido del tipo temática. Se identificó que 16 participantes mencionaron 95 referencias relacionadas con la categoría Preocupación por la Seguridad del Paciente, como la falta de control de acceso, la falta de comunicación, el riesgo de infección y otros aspectos relacionados con la dinámica de trabajo. Aún así, fue posible detectar 196 referencias relacionadas con la categoría Estrategias para la Seguridad del Paciente, y todos los compañeros presentaron al menos una, tales como: provisión de un servicio com excelencia, cuidar con amor, y el mantenimiento de un entorno seguro. La importancia de la inclusión del compañero en el proceso de cuidar fue reafirmada en el final del estudio, confirmando el facto del familiar analizar como el equipo de salud asiste el niño, siendo considerado socio en el tratamiento. Es posible estresar como principales contribuciones del estudio el reconocimiento de la presencia del compañero y la responsabilidad atribuida a él en la hospitalización, especialmente en neonatología; la posible cualificación de asistencia al niño hospitalizado, a partir de la adopción de conductas, por los profesionales de salud, en conformidad con las estrategias descriptas por los participantes; y, consecuentemente, el desarrollo de una cultura de seguranza.
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Influência de gênero no desenvolvimento somático e sensório motor de ratos wistar submetidos à anóxia neonatal / Not informed by the authorKumar, Amrita Jha 24 February 2017 (has links)
Na atualidade, uma das causas importantes de lesão encefálica em neonatos é a anóxia neonatal. Este é um problema grave nos serviços de perinatologia dos hospitais em todo o mundo sendo ainda pior em países subdesenvolvidos, devido à carência de precauções e cuidados requeridos. Modelos animais de anóxia vêm sendo empregados para avaliar seus efeitos, tanto em nível neurológico, como em nível comportamental. A anóxia neonatal tem sido estudada pelo laboratório de Neurociências do Instituto de Ciências Biomédicas da Universidade de São Paulo, com modelos de estudo já desenvolvidos, adaptados e validados. Para investigar se a anóxia neonatal afeta o desenvolvimento motor somático e sensorial, ratos foram submetidos a um modelo não invasivo de anóxia global (Takada et. al., 2011). Ratos Wistar com 30 h de idade (6-8 gramas), machos e fêmeas, foram expostos por 25 minutos a gás nitrogênio 100% num fluxo de 3L/min, pressão 101.7 kPa e temperatura de 37ºC em câmara semi-hermética de policarbonato. O grupo controle foi submetido às mesmas condições porem com o ar ambiente normal. Os animais foram avaliados durante o período de aleitamento (P2 a P21) quanto a parâmetros do desenvolvimento somático; desenvolvimento ontogenético e quanto a reflexos sensório motores. Os resultados indicaram que o grupo Anoxia macho(AM) apresentou aumento no peso corporal {AM(42.25±3.62);CM(38.76±5.60);AF(40.64±5.08);CF(41.33±5.45)}e diminuição do eixo longitudinal do corpo {AM(10.15±0.27);CM(10.39±0.50);AF(9.82±0.44);CF(10.82±0.46)} em relação ao grupo Controle macho(CM) e Anoxia fêmea(AF), AF foi menor em relacao ao Controle fêmea (CF). AM apresentou maior eixo látero-lateral do crânio em relação CM e AF {AM (3.18 ±0.10); CM (3.17 ±0.13); AF(3.06 ±0.16); CF(3.00 ±0.15)} No desenvolvimento ontogenético houve retardo na abertura do canal auditivo {AM (13.79± 0.58); CM (13.75±0.83); AF(14.21±1.01); CF(13.36±0.50)} e abertura dos olhos {AM (14.00± 0.88); CM (14.64±1.28); AF(15.14±0.86); CF(13.79±0.42)} no grupo AF em relação a CF e AM, mas no grupo AM não houve diferença significante. Na erupção dos incisivos superiores {AM (10.79± 0.43); CM(11.71±1.68); AF(11.43±0.65); CF(10.07±0.27)} o grupo AM adiantou enquanto o AF atrasou em relação ao grupo controle. A avaliação dos reflexos sensóriais mostrou que a anoxia adiantou a colocação pelas vibrissas {AM (8.80± 1.21); CM (9.50±1.56); AF (9.93±1.14); CF(10.14±1.28) no AF e AM. Apenas o AM adiantou {AM (10.93± 2.09); CM(13.43±0.94); AF(10.50±0.85); CF(9.57±0.76)} no reflexo de aversão ao precipício. Nos relfexos de geotaxia negativa {AM (14.87± 1.30); CM (13.57±2.34); AF(14.57±1.40);CF (12.00±2.11)} e sobressalto ao susto {AM (14.00±0.53); CM (13.21±1.31); AF (13.29±0.61); CF (11.93±0.27)} e preensão palmar {AM (6.60±0.83); CM (4.71±0.47); AF(10.14±0.83); CF(4.71±0.47)} a anóxia provocou atraso tanto em macho quanto em fêmeas motores. Houve atraso na ontogênese da maioria dos testes de reflexos dos filhotes do grupo Anóxia. Os resultados deste estudo demonstraram que a anóxia causa danos persistentes na maioria dos parâmetros avaliados em relação aos grupos controle, e diminuição no número de neurônios do córtex sensóriomotor {M2: AM (46.84±1.72); CM (52±1.66); AF (45.55±1.80); CF (52±1.55)M1: AM (23.70±1.33); CM (41.89±1.49); AF (25.69±0.83); CF (43.88±1.46) S1HL: AM (27.93±2.69); CM (30.19±1.31); AF(23.42±2.38); CF (38.88±1.48) S1FL: AM (31.85±1.09); CM (33.88±0.48); AF(27.66±1.36); CF(32.28±1.70)}, com diferença de gênero o que evidencia a importância de que estratégias e procedimentos para minimizar os efeitos desse estímulos sejam consideradas em relação ao gênero / At present, one of the important causes of brain injury is the neonatal anoxia. This is a serious problem in the perinatology services of hospitals around the world being even worse in underdeveloped countries because of the lack of precautions and care required. Animal models of anoxia have been employed to assess their effects, both at the neurological level and at the behavioral level. Neonatal anoxia has been studied by the Neuroscience Laboratory of the Biomedical Sciences Institute of the University of São Paulo, with animal models already developed, adapted and validated. To investigate whether neonatal anoxia affects somatic and sensory motor development, rats were subjected to a non-invasive model of global anoxia (Takada et al., 2011). Male and female 30-h old (6-8 grams) Wistar rats were exposed for 25 minutes to 100% nitrogen gas in a flow of 3 L/min, pressure 101.7 kPa and temperature of 37ºC in a semi-hermetic chamber of polycarbonate. The control group was subjected to the same conditions but with normal ambient air. The animals were evaluated during the lactation period (P2 to P21) for parameters of somatic development; Ontogenetic development and for sensorimotor reflexes. The results indicated that the male Anoxia (AM) group presented increase in body weight (AM (42.25 ± 3.62), CM (38.76 ± 5.60), FA (40.64 ± 5.08), CF (41.33 ± 5.45)) and decrease in the longitudinal (10.82 ± 0.46), in relation to the male control group (CM) and the female Anoxia (AF), AF was lower in relation to the control group (AM) (10.15 ± 0.27), CM (10.39 ± 0.50), AF (9.82 ± 0.44) Female control (CF). AM increase in the cranio-lateral axis in relation to CM and AF (AM (3.18 ± 0.10); CM (3.17 ± 0.13); AF (3.06 ± 0.16); CF (3.00 ± 0.15). Concerning the ontogenetic development there was delay in opening the (13.79 ± 0.58), and the eyes {AM (14.00 ± 0.88); CM (14.64 ± 1.28), AF (15.14 ± 0.86), CF (13.79 ± 0.42)} in the AF group in relation to CF and AM, but in the AM group there was no significant difference. In the eruption of maxillary incisors (AM (10.79 ± 0.43), CM (11.71 ± 1.68), AF (11.43 ± 0.65), CF (10.07 ± 0.27), the AM group advanced while the AF delayed in control ration. The evaluation of the sensory reflexes showed that anoxia improved the placement of vibrissae (AM (8.80 ± 1.21), CM (9.50 ± 1.56), AF (9.93 ± 1.14), CF (10.14 ± 1.28) in AF and AM. Only AM advanced (AM (10.93 ± 2.09), CM (13.43 ± 0.94), AF (10.50 ± 0.85), CF (9.57 ± 0.76) in the reflex of aversion to the precipice. In negative geotaxia relays (AM (14.87 ± 1.30); CM (13.57 ± 2.34), AF (14.57 ± 1.40), CF (12.00 ± 2.11)} and startle reflex {AM (14.00 ± 0.53); CM (13.21 ± 1.31); AF (13.29 ± 0.61); CF (11.93 ± 0.27) and palmar grip (AM (6.60 ± 0.83); CM (4.71 ± 0.47), AF (10.14 ± 0.83), CF (4.71 ± 0.47)), anoxia caused delay in both male and female groups. There was a delay in the ontogenesis of most of the reflex tests of the puppies of the anoxia group. The results of this study demonstrated that anoxia causes persistent damage in most of the parameters evaluated in relation to the control groups, and a decrease in the number of sensory motor cortex neurons (M2: AM (46.84 ± 1.72), CM (52 ± 1.66), AF 1.80), CF (52 ± 1.55) M1: AM (23.70 ± 1.33), CM (41.89 ± 1.49), AF (25.69 ± 0.83), CF (43.88 ± 1.46) S1HL: AM (27.93 ± 2.69), CM (30.19 (31.88 ± 1.48), FA (27.66 ± 1.36), CF (32.28 ± 1.70), , which shows that strategies and procedures to minimize the effects of such stimuli should be considered in relation to gender
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