Esta dissertação expõe uma investigação sobre como a música pode tocar o sujeito humano, sobretudo no Real da teoria lacaniana, em uma experiência denominada, pelo psicanalista francês Alain Didier-Weill, Nota Azul, e perscrutar elementos da música que atingem o sujeito ouvinte no que ele sente e pensa o traduzir e mobilizar identificações da ordem racional e da ordem inconsciente. O trabalho constitui-se de um levantamento teórico sobre o entendimento da música como linguagem, a partir dos olhares da Linguística e da Psicanálise, expondo a forma como a música pode falar sobre os mais diversos afetos humanos aquilo que se sabe dizer sobre o que se sente e também aquilo que escapa à linguagem. Atém-se à teoria da Nota Azul, que vem falar desse lugar inapreensível pelo entendimento. Apresenta a pesquisa qualitativa realizada, composta de entrevista com cinco sujeitos músicos em escuta sobre suas experiências como ouvintes de música e sobre como se sentem tocados por ela. A análise de dados seguiu as diretrizes da análise de conteúdo de Bardin (2016). Os resultados obtidos trouxeram dados significativos sobre como a música é uma importante via da arte que tenta dar conta de questões profundas do sujeito humano. / The present dissertation exposes an investigation about the way music can touch the human subject, especially in relation to the Real in lacanian theory, in an experience called the Blue Note by French psychoanalyst Alain Didier-Weill, and examines musical elements which touch the listener in what he/she feels and thinks translating and mobilizing identifications in rational and unconscious level. The work is a theoretical research about music as language, from the Linguistics and Psychoanalysis perspective, showing the way music can talk to a variety of human affections what it is possible to be said and also what escapes from language. The theory of Blue Note talks about this place which is inapprehensible. We use qualitative research, with interviews made with five musicians when they shared their experiencies as music listeners and how they feel touched by it. The data analysis followed the content analysis guidelines by Bardin (2016). The results brought significant data about how music is an aspect of art that tries to understand deep issues about the human subject.

L’hydroperoxyde lyase (HPL) est une enzyme issue de la voie de la lipoxygénase, voie métabolique très représentée chez les végétaux, impliquée dans la production de composés aromatisants (l’hexanal, le 3Z-hexenal et le 2E-hexenal). Ces composés sont responsables de l’odeur fraîche de l’herbe coupée dite « note verte » et sont très utilisés par les industries cosmétiques et agroalimentaires. Leur biosynthèse résulte de l’oxydation des acides gras polyinsaturés en hydroperoxydes par la lipoxygénase, puis de leur clivage par l’hydroperoxyde lyase (HPL). Les procédés actuels de production de ces composés présentent certains inconvénients, ils sont notamment très polluants et peu performants, aussi l’utilisation d’enzymes recombinantes dans de tels procédés permettrait d’obtenir ces molécules de manière plus efficace tout en bénéficiant du label "naturel". L’ADNc codant pour l’hydroperoxyde lyase (HPLwt) a été isolé au laboratoire à partir d’olives noires. Afin d’améliorer la solubilité de l’enzyme, une HPL dépourvue de son peptide de transit chloroplastique (HPLdel) a également été produite. Les deux enzymes ont été exprimées chez E.coli, purifiées par chromatographie d’affinité puis caractérisées biochimiquement. Elles agissent exclusivement sur les 13-hydroperoxydes (13-HPL) à un pH et une température optimum de 7,5 et 25°C. De plus l’évaluation des paramètres cinétiques de l’enzyme montre qu’elles ont une meilleure efficacité catalytique (kcat/Km) sur les 13-hydroperoxydes d’acide linolénique (3,68 s-1.µM-1) que sur les 13-hydroperoxydes d’acide linoléique (0,54 s-1.µM-1). La bioconversion des 13-hydroperoxydes d’acide linoléique et linolénique en hexanal et 3Z-hexénal par l’action de l’HPLwt et l’HPLdel a été étudiée. Des taux de conversion maximum atteignant 93 % et 68 % pour la production d’hexanal et 73 % et 45% pour la production d’3Z-hexénal ont été obtenus quand l’HPLwt et l’HPLdel sont utilisées respectivement. La stabilité de l’enzyme a ensuite été étudiée. Des essais de conservation montrent que l’utilisation de glycérol à 10% (v/v) permet le maintien de la totalité de l’activité de l’HPLwt et de l’HPLdel durant cinq semaines de stockage à -80°C. De plus, l’ajout de composés chimiques tels que le KCl, le NaCl, le Na2SO4, la glycine et le glycérol permettent d’augmenter l’activité enzymatique des deux enzymes et d’améliorer les conditions de synthèse de l’hexanal et du 3Z-hexénal en diminuant la quantité d’enzyme nécessaire à leur production. / The hydroperoxide lyase (HPL) derives from a metabolic pathway named lipoxygenase pathway widely represented in plants and involved in the production of flavoring compounds (hexanal, 3Z-hexenal and 2E-hexenal). These volatile compounds are responsible for the fresh odor of cut grass known as "green note" and have a particularly interest for flavor and food industries. Their biosynthesis results from the oxygenation of linoleic and linolenic acids by lipoxygenase action to form fatty acid hydroperoxides, then of their cleavage by hydroperoxide lyase action. The processes of production currently used are highly polluting or lead to a low yield. To overcome these drawbacks, the use of recombinant enzymes in such processes constitutes an attractive alternative because they would allow producing these molecules in a more effective way, while benefiting from the "natural" label.A cDNA encoding for HPL (HPLwt) from black olive fruit was isolated, and in order to improve the enzyme solubility, the HPL deleted of its chloroplast transit peptide (HPLdel) was then produced. Both enzymes were expressed into E. coli (M15), purified by affinity chromatography, and characterized. They act exclusively on 13-hydroperoxide (13-HPL) and display an optimum pH at 7.5 and an optimum temperature at 25 °C. The bioconversion of 13-hydroperoxides of linoleic and linolenic acids in hexanal and 3Z-hexenal respectively, using HPLwt or HPLdel was studied. Conversion yields reach a maximum of 93 % and 68 % for hexanal production, and 73 % and 45 % for 3Z-hexenal when reactions were performed by HPLwt and HPLdel respectively.The enzyme stability was then studied. Conservations tests using 10 % glycerol (v/v) allows the maintenance of the entire activity of HPLwt and HPLdel during five weeks of storage at -80°C. Furthermore, the addition of chemical compounds such as KCl, NaCl, Na2SO4, glycine, and glycerol can increase the efficiency of both enzymes and improve the synthesis of hexanal and 3Z-hexenal by decreasing the amount of enzyme required to produce them.

Dans les collèges français, la question de l'éducation fait l'objet d'un traitement assez sombre : au niveau statutaire, elle marque en effet le faible prestige de certains personnels, ou de certaines matières enseignées. C'est le cas des conseillers et assistants d'éducation, ou, sur un autre plan, de l'éducation artistique, de l'éducation civique ou de l'éducation physique et sportive. La connotation négative de l'éducation apparait aussi dans les discours quotidiens, enclins à dénoncer des carences. L'écart social entre les membres des classes moyennes cultivées et leurs élèves ne prédit pas, cependant, le niveau de tension. La construction d'un climat d'établissement joue en effet une fonction importante ; en second lieu, les situations éducatives les moins aisées obligent précisément à réfléchir en termes éducatifs. Il en ressort souvent un meilleur climat que dans des établissements peu exposés. Dans l'imaginaire des professionnels, le collège n'aurait d'autre but que d'organiser la succession de cours entre enseignants savants et apprenants captivés. Depuis les débuts de la massification, les professeurs appliquent en réalité des pédagogies " bricolées ", sans rapport avec les principes idéels. Malgré ces adaptations officieuses, les collégiens sont pénalisés par la segmentation des cours, l'étouffement de l'esprit critique, la faible intégration éducative et la relégation du " sale boulot " de discipline. Dans les établissements favorisés, l'insuffisance démocratique incite plutôt a l'utilitarisme, et au développement d'une culture juvénile anti-scolaire ; dans les collèges populaires, les élèves en échec peuvent aussi opposer une violence.

This research focuses on the development and study of socially appropriate ways to archive data about important life experiences during unexpected and unstructured situations. This work involves three significant phases: formative studies to understand the data capture needs of particular populations of users in these situations; design and development of a technical architecture for capture and access in these settings coupled with design and development of applications for two specific domain problems; and evaluation of this solution as it pertains to these domain problems. The underlying solution presented in this dissertation is known as selective archiving, in which services are always on and available for recording but require some explicit action to archive data. If no such action is taken, recorded data is deleted automatically after a specified time. Selectively archived segments of data can provide an efficient way to recover and to analyze high quality data that traditionally available. The projects presented in this dissertation provide insight about the ways in which we can support record-keeping in informal and unstructured settings. Furthermore, when examined together, these projects provide a view into the larger generalized problem of unstructured capture and access and the acceptability of capture technologies. These considerations evolved into a set of seven tensions surrounding recording technologies that are presented in this dissertation. Furthermore, the experiences surrounding the deployment and evaluation of selective archiving technologies demonstrate the ways in which people use different types of knowledge and cues from the world to determine their reactions to and adoption of such technologies.

This research explores the annotation and note-taking practices of graduate students and reports on the sets of activities, habits, objects, tools and methods that define the practice. In particular, this empirical study focuses on understanding the integration of annotation practices within larger scholarly processes. This study therefore aims to describe and analyze annotation not only as material externalities of the research process, but also as crucial epistemic practices allowing students to progress from one research activity to the other. Interviews are supplemented by document collection and analyzed using a multi-perspectival framework. The findings describe an annotation lifecycle and suggest a new model of the scholarly process using annotation practices as units of analysis. The study further discusses annotation as a primitive epistemic practice and examines the productive tensions fostering the student’s progress towards her goals. This research finally proposes requirements for future tools supporting scholarly practice.

This research explores the annotation and note-taking practices of graduate students and reports on the sets of activities, habits, objects, tools and methods that define the practice. In particular, this empirical study focuses on understanding the integration of annotation practices within larger scholarly processes. This study therefore aims to describe and analyze annotation not only as material externalities of the research process, but also as crucial epistemic practices allowing students to progress from one research activity to the other. Interviews are supplemented by document collection and analyzed using a multi-perspectival framework. The findings describe an annotation lifecycle and suggest a new model of the scholarly process using annotation practices as units of analysis. The study further discusses annotation as a primitive epistemic practice and examines the productive tensions fostering the student’s progress towards her goals. This research finally proposes requirements for future tools supporting scholarly practice.

Made available in DSpace on 2015-03-26T13:32:07Z (GMT). No. of bitstreams: 1 texto completo.pdf: 1363370 bytes, checksum: c1941f11abc68868beaef6fe7462af56 (MD5) Previous issue date: 2008-11-17 / Conjoint analysis is a regression analvsis that uses a model with dummy or indicator explanatory variables to study consumer preference for treatments that can be products or services, and are defined by combining levels of each attribute or factor. lt allows the estimation of the Relative Importance (RI ) of each factor that makes up the treatments. Such studies are important to help decide, based on RI estimates obtained from the CA, to which factors should be given more attention when developing the products and/or services. In this research work we conducted a simulation study in order to investigate the robustness of the RI sampling distribution to departures from normality for the distribution of the random error term (&#1108;) of the CA model. We simulated four alternative distributions for &#1108; and generated data (acceptance notes) that allowed estimation of RI for hypothetical factors A, B, C and D considered in our study. In addition to the normal distribution, we used a location and scale transformation of the beta density to generate three alternative distributions: right skewed, left skewed, and also an U-shape distribution. Each one of these four distributions was tested with two standard error values (&#963; = 2.8 and 0.5) which resulted in eight alternative scenarios. Our simulation study considered factors A and B with 3 levels and factors C and D with two levels, hence 36 treatments in a full factorial design. We set reference RI values of 44.25%, 25.66%, 26.55% and 3.54%, respectively for factor A, B, C and D, and simulated data such that each treatment was evaluated by 108 consumers. This data set with 3888 observations was simulated 100 times for each scenario and analyzed by CA which resulted in 100 RI estimates for each factor at every scenario. Results were investigated by 95% confidence intervals (Cl) using the usual normal approximation and also percentile intervals, histograms of RI values sampling distribution to check normality, and also we calculated relative mean errors of estimation (RME) with respect to the reference RI values It was observed that the confidence intervals included the values of RI´s taken as reference in all scenarios, with the exception of: (i) factors A and B, with the normal Cl using normal distribution and &#963; = 2.8; ( i i ) wi th normal Cl and &#963; = 0.5, (iia) for factors A and C with normal distribution, U shaped and left skewed; (iib) for factor B with U shaped model and (iic) for factor D with normal distribution and U shaped. In al l these cases were the Cl missed the RI reference value, we observed close miss left and miss right results. We observed RME < 5% in all scenarios except for normal distribution and factor D only, for which RME = 7.91%. We concluded that sampling distribution of the estimator of the RI of a factor is relatively robust to departures from the normal distribution. In fact, results showed that i t s sampl ing dist r ibut ion must be close to the normal, regardless of the distribution of the random error term of the CA model. / Conjoint analysis ou análise conjunta de fatores (ANCF) é uma análise de regressão que utiliza um modelo com variáveis explicativas indicadoras ou dumnmy, para se estudar a preferência de consumidores por tratamentos que podem ser servidos ou produtos, e que são definidos pela combinação de níveis de diversos atributos ou fatores. Com essa técnica estima-se a Importância Relativa (IR) de cada fator que compõe os tratamentos avaliados. Tais estudos são importantes por permitir decidir, com base nas estimativas das IR de cada fator, quais devem ser observados com maior atenção na definição do tratamento. No presente trabalho foi realizado um estudo por simulação para se investigar a robustez da distribuição amostral do estimador da IR de um fator, à variação na distribuição do erro aleatório do modelo de regressão empregado na ANCF. Foram gerados erros aleatórios com a distribuição normal e também três outras distribuições alternativas obtidas por uma transformação de locação e escala da beta: uma distribuição assimétrica à direita, outra assimétrica à esquerda e uma com forma U. Para cada distribuição, utilizou-se desvio-padrão &#963; = 2,8 e &#963; = 0,5, portanto para oito condições foram simulados 100 conjuntos de dados referentes a avaliações (notas de aceitação) de 108 consumidores para cada um dos 36 tratamentos formados pela combinação de 4 fatores (A, B, C e D) num esquema fatorial completo 32 x 22. Definiu-se com base em um modelo de regressão para ANCF, valores de referências para as IR's iguais a 44,25%, 25,66%, 26,55% e 3,54%, respectivamente para os fatores A, B. C e D. Na avaliação dos resultados com base em intervalos de confiança percentil e pela aproximação normal, ambos a 95%, verificou-se intervalos mais estreitos pela aproximação normal. Conforme esperado, verificou-se intervalos de confiança para as IR´s mais amplos quando &#963; = 2,8. Observou-se que todos os intervalos de confiança incluíram os valores das IR's tomados como referência, exceto para os seguintes casos: (i) intervalo de confiança pela aproximação normal para a simulação de erros com distribuição normal e &#963; = 2,8, para os fatores A e B; (ii) com intervalo pela aproximação normal e &#963; = 0,5, (iia) para os fatores A e C com distribuição normal, em forma de U e assimétrica à esquerda; (iib) para o fator B com distribuição em forma de U; e (iic) para o fator D com distribuição normal e em forma de U . Entretanto, neste casos de não inclusão do valor IR de referência nos intervalos, observou-se que o valor estava próximo ao limite do IC, tanto à esquerda quanto à direita. As estimativas de IR obtidas no estudo por simulação também foram avaliadas pelo Erro Médio Relativo (EMR) com relação aos respectivos valores de referência. Exceto para o fator D na simulação com erros normais e &#963; = 2,8, na qual se obteve EMR = 7,91%, em todas as demais situações simuladas obteve-se EMR < 5%. Adicionalmente, o teste de Kolmogorov-Smirnov indicou normalidade (p > 0,05) das distribuições amostrais em todos os casos. Concluiu-se que o estimador da IR pode ser considerado como robusto à não nor-malidade da distribuição do erro aleatório do modelo de regressão utilizado na ANCF. Adicionalmente, pode-se considerar que a distribuição amostral da IR seja normal e que portanto métodos inferenciais que requerem normalidade podem ser aplicados às estimativas de lR's obtidas na ANCF.

abstract: The problem under investigation was to determine if a specific outline-style learning guide, called a Learning Agenda (LA), can improve a college algebra learning environment and if learner control can reduce the cognitive effort associated with note-taking in this instance. The 192 participants were volunteers from 47 different college algebra and pre-calculus classes at a community college in the southwestern United States. The approximate demographics of this college as of the academic year 2016 – 2017 are as follows: 53% women, 47% men; 61% ages 24 and under, 39% 25 and over; 43% Hispanic/Latino, 40% White, 7% other. Participants listened to an approximately 9-minute video lecture on solving a logarithmic equation. There were four dependent variables: encoding as measured by a posttest – pretest difference, perceived cognitive effort, attitude, and notes-quality/quantity. The perceived cognitive effort was measured by a self-reported questionnaire. The attitude was measured by an attitude survey. The note-quality/quantity measure included three sub-measures: expected mathematical expressions, expected phrases, and a total word count. There were two independent factors: note-taking method and learner control. The note-taking method had three levels: the Learning Agenda (LA), unguided note-taking (Usual), and no notes taken. The learner control factor had two levels: pausing allowed and pausing not allowed. The LA resulted in significantly improved notes on all three sub-measures (adjusted R2 = .298). There was a significant main effect of learner control on perceived cognitive effort with higher perceived cognitive effort occurring when pausing was not allowed and notes were taken. There was a significant interaction effect of the two factors on the attitude survey measure. The trend toward an improved attitude in both of the note-taking levels of the note-taking factor when pause was allowed was reversed in the no notes level when pausing was allowed. While significant encoding did occur as measured by the posttest – pretest difference (Cohen’s d = 1.81), this measure did not reliably vary across the levels of either the note-taking method factor or the learner control factor in this study. Interpretations were in terms of cognitive load management, split-attention, instructional design, and note-taking as a sense-making opportunity. / Dissertation/Thesis / Doctoral Dissertation Educational Technology 2018

Muitas controvérsias cercam, atualmente, a negociação da Cédula de Crédito Bancário (CCB), dividindo a doutrina e atraindo a atenção do mercado financeiro e de capitais. A discussão central gira em torno da natureza jurídica da CCB, mais especificamente de seu enquadramento no conceito de valor mobiliário, do qual decorreria a competência da Comissão de Valores Mobiliários para regulamentar e supervisionar as ofertas públicas de CCBs. A análise da natureza jurídica da CCB torna-se, assim, imperativa para a delimitação do campo de atuação da Comissão de Valores Mobiliários. Para fins dessa análise, examina-se neste trabalho, inicialmente, o conceito e características dos títulos de crédito e valores mobiliários. Analisa-se, ainda, o conceito de CCB, sua origem, finalidade no âmbito do mercado financeiro, elementos característicos e modelos de negociação. Este trabalho também tem por escopo a investigação dos riscos associados à CCB e o exame da necessidade e das formas de se assegurar a proteção dos investidores. Diante dos elementos característicos da CCB e do conceito de valor mobiliário adotado pelo direito brasileiro, este trabalho conclui sobre a não caracterização da CCB como valor mobiliário. Este trabalho propõe-se, ainda, a concluir sobre os mecanismos adequados de proteção daqueles que investem em CCBs, em vista dos riscos inerentes a esse título de crédito. / Several controversies currently surround the trading of Bank Credit Note (Cédula de Crédito Bancário - CCB), dividing the doctrine and attracting the attention of financial and capital market. The main discussion is around the legal nature of CCB, more precisely around the characterization of CCB as security, from which would arise the competence of the Brazilian Securities Commission to regulate and supervise the public offering of CCBs. The exam of the legal nature of the CCB becomes, therefore, imperative for delimitation of the actuation field of Brazilian Securities Commission. For purpose of this analysis, it is initially examined in this work the concept and characteristics of the titles of credit and securities. It is also examined the concept of CCB, its origin, purposes within the financial market, characteristics elements, and trading models. This work has also as scope the investigation of the risks associated to CCB and the exam of the need and forms to assure the investors protection. Considering the characteristics elements of CCB and the concept of security adopted by Brazilian law, this work concludes that the CCB does not constitute a security. This work also concludes on the proper mechanisms for the protection of those who invest in CCBs, given the risks inherent to such title of credit.

Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2017-05-18T15:11:30Z No. of bitstreams: 2 Dissertação - Nivaldo Camargo de Moura Junior - 2017.pdf: 1466523 bytes, checksum: 80c9af280aa6ffe1182c1a3b7b33d6e9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-05-18T15:12:01Z (GMT) No. of bitstreams: 2 Dissertação - Nivaldo Camargo de Moura Junior - 2017.pdf: 1466523 bytes, checksum: 80c9af280aa6ffe1182c1a3b7b33d6e9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2017-05-18T15:12:01Z (GMT). No. of bitstreams: 2 Dissertação - Nivaldo Camargo de Moura Junior - 2017.pdf: 1466523 bytes, checksum: 80c9af280aa6ffe1182c1a3b7b33d6e9 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-04-01 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Abstract: The present research was developed through the application of the Group of Notes, concept presented by James Morgan Thurmond (1991) in the book: Note Grouping: A Method for Achieving Expression and Style in Musical Performance, being used as tool for interpretative suggestion in the work Estudo Para Trompete em Dó, by the Brazilian composer Camargo Guarnieri. Initially a bibliographical survey was carried out on the research and repertoire productions related to the interpretive practices for solo trumpet in Brazil, as well as a historical and methodological linkage of musical expressiveness, approaching the pedagogy of musical expressiveness, the grouping of notes and finally the application of this concept as an interpretative suggestion in specific sections of the work, object of study researched. / Resumo: A presente pesquisa desenvolveu-se através da aplicação do Agrupamento de Notas, conceito apresentado por James Morgan Thurmond (1991) no livro: Note Grouping: A Method for Achieving Expression And Style in Musical Performance, utilizando-se como ferramenta para sugestão interpretativa na obra Estudo para trompete em Dó, do compositor brasileiro Camargo Guarnieri. Inicialmente realizou-se um levantamento bibliográfico sobre as produções de pesquisas e repertório relacionados às práticas interpretativas para trompete solo no Brasil, bem como uma vinculação histórica e metodológica da expressividade musical, abordando a pedagogia da expressividade musical, o agrupamento de notas e, por último, a aplicação deste conceito como sugestão interpretativa em trechos específicos da obra, objeto de estudo pesquisado.