The Swedish Sea Rescue Society (SSRS) is a non-profit organisation which performs themajority of rescue missions on Swedish waters. SSRS together with many other companies arecurrently under development of a novel boat design which is battery powered. This leads to aspecific challenge of shorter available reach compared to the traditional diesel engine poweredboats. The solutions is to make use of hydrofoils which enables the potential for the hull to belifted above sea level and reduce drag resistance by up to 80% The purpose of the project was to through a broad background study, develop systems that allowretraction and extension of the hydrofoil from the hull of the boat. After generating 10 concepts,these were evaluated by performing an elimination- and decision matrix. Two concepts werechosen to be further developed. The two concepts were in many aspects similar in regards tocomponents and the outline of them except one was actuated by a multi-stage hydraulic cylinderand the other by a servo motor and roller screw. Analytical calculations, choice- anddimensioning of components and FE-analysis in NX Nastran were done in the furtherdevelopment-stage. It was found that both solutions were viable options to integrate as hydrofoil extension andretraction mechanisms on an electric boat. After completion and interpretation of the results itwas concluded that an electromechanical solution would be prefered to use as the underlyingtechnology for the lifting mechanism. / Svenska sjöräddningssällskapet (SSRS) är en ideell organisation som utför majoriteten avräddningsuppdrag i Sverige. SSRS tillsammans med flera andra företag är under utveckling aven ny båtdesign som ska drivas av el, vilket leder till en specifik utmaning i form av en kortaretillgänglig körsträcka gentemot den traditionellt drivna motorbåten. Lösningen är att använda sigutav s.k. bärplan, vilket möjliggör skrovet på båten att lyftas över vattenytan och reducerarfriktionskrafterna med upp till 80%. Projektet gick ut på att genom en bred bakgrundsstudie utveckla koncept av system som tillåterin- och utfällning av detta bärplan från båtens skrov. Efter en generering av 10 varierandekoncept sållades dessa ut genom en eliminerings- samt beslutsmatris. Två av dessa konceptvaldes att utveckla vidare. Dessa två koncept var i många hänseenden identiska i utformning avkomponenter med skillnaden att den ena var driven av en teleskopisk, 2-stegs, dubbelagerandehydraulcylinder och den andra med en servomotor och rullskruv för att utföra linjär rörelse.Analytiska beräkningar, urval och dimensionering av komponenter samt FE-analyser i NXNastran gjordes i vidareutvecklingen av koncepten. Båda koncepten visade sig vara lämpliga alternativ i tillämpningen som mekanism till ett ut- ochinfällbart bärplanssystem på en eldriven båt. Efter slutsats och tolkning av resultatet framgick detatt den elektromekaniska lösningen nog skulle vara den mest lämpliga teknologin bakomlyftmekanismen.

Recanting is a recognized phenomenon in child sexual abuse cases, particularly in cases of incest. When children report cases of sexual abuse, it often set motions in their environment to safeguard them from experiencing further abuse. Children may decide to take back their allegations, in most cases leading to recanting. When children recant, it may be a way to attempt to put their world back to the way it was before anyone found out about the abuse. This behaviour is often misunderstood by professionals who may conclude prematurely that the abuse never occurred in the first place. The child may want the abuse to end but never imagined the consequences of the disclosure for them and the family. The aim of this research is to find out the reasons why children recant their disclosures of sexual abuse. The study suggests that there are various reasons why children recant their disclosures of sexual abuse ranging from fear, socio economic reasons, threats and disbelief from their parents or caregivers. It also suggests that there is a need for social workers to be trained on dealing with children who have recanted their disclosures of sexual abuse and to emphasize on getting therapy for the child that has recanted the sexual abuse allegations. / MSW (Forensic Practice), North-West University, Potchefstroom Campus, 2014

Recanting is a recognized phenomenon in child sexual abuse cases, particularly in cases of incest. When children report cases of sexual abuse, it often set motions in their environment to safeguard them from experiencing further abuse. Children may decide to take back their allegations, in most cases leading to recanting. When children recant, it may be a way to attempt to put their world back to the way it was before anyone found out about the abuse. This behaviour is often misunderstood by professionals who may conclude prematurely that the abuse never occurred in the first place. The child may want the abuse to end but never imagined the consequences of the disclosure for them and the family. The aim of this research is to find out the reasons why children recant their disclosures of sexual abuse. The study suggests that there are various reasons why children recant their disclosures of sexual abuse ranging from fear, socio economic reasons, threats and disbelief from their parents or caregivers. It also suggests that there is a need for social workers to be trained on dealing with children who have recanted their disclosures of sexual abuse and to emphasize on getting therapy for the child that has recanted the sexual abuse allegations. / MSW (Forensic Practice), North-West University, Potchefstroom Campus, 2014

Hypercholesterolemia is a dominant risk factor for a variety of cardiovascular diseases and involves a chronic inflammatory component in which neutrophil activity plays a critical role. Recently, fluid shear stress mechanotransduction has been established as a control mechanism that regulates the activity of neutrophils by reducing the formation of pseudopods and the surface expression of CD18 integrins, thereby rendering these cells rounded, deformable, and non-adhesive. This is critical for maintaining a healthy circulation, because chronically activated neutrophils not only release excess cytotoxic and degradative agents but also exhibit a reduced efficiency to pass through the small vessels of the microcirculation leading to increased microvascular resistance. We hypothesized that aberrant neutrophil mechanosensitivity to fluid shear stress due to the altered blood environment (i.e., excess plasma cholesterol) is a contributing factor for elevated hemodynamic resistance in the microcirculation associated with hypercholesterolemia. For this purpose, the present work firstly showed that the sensitivity of neutrophils to fluid shear stress depends on the cholesterol-dependent fluidity of the cell membrane, and that, in the face of hypercholesterolemia, the neutrophil mechanosensitivity highly correlated with the plasma levels of free cholesterol. The second part of this project demonstrated that, when subjected to shear stress fields, leukocyte suspensions exhibited transient (within 10 min of flow onset) time-dependent reductions in their apparent viscosity. Moreover, shear-induced changes in viscosity of cell suspensions were influenced by disturbances of membrane cholesterol and fluidity in a fashion similar to that for shear-induced pseudopod retraction. Finally, the third part of this work provided evidence that neutrophils played a role in hypercholesterolemia-related impairment of flow recovery response to transient ischemia. In conclusion, results of the current work provided the first evidence that cholesterol is an important component of the neutrophil mechanotransducing capacity and impaired neutrophil shear mechanotransduction may disturb the blood flow rheology, leading to elevations in the apparent viscosity as well as in the resistance. This cholesterol-linked perturbation may be a contributing factor for the pathologic microcirculation associated with hypercholesterolemia.

If X is a simply connected CW complex, then it has a unique (up to isomorphism) minimal Sullivan model. There is an important rational homotopy invariant, called the rational Lusternik–Schnirelmann of X, denoted cat0(X), which has an algebraic formulation in terms of the minimal Sullivan model of X. We study another such numerical invariant called the rational retraction index of X, denoted r0(X), which is defined in terms of the minimal Sullivan model of X and satisfies 0 ≤ r0(X) ≤ cat0(X). It was introduced by Cuvilliez et al. as a tool to estimate the rational Lusternik–Schnirelmann category of the total space of a fibration. In this thesis we compute the rational retraction index on a range of rationally elliptic spaces, including for example spheres, complex projective space, the biquotient Sp(1) \ Sp(3) / Sp(1) × Sp(1), the homogeneous space Sp(3)/U(3) and products of these. In particular, we focus on formal spaces and formulate a conjecture to answer a question posed in the original article of Cuvilliez et al., “If X is formal, what invariant of the algebra H∗(X;Q) is r0(X)?”

Retalho posicionado coronalmente associado ao enxerto de tecido conjuntivo subepitelial (ETCS) é o padrão ouro para o tratamento de retrações gengivais. A matriz de colágena suína bioabsorvível Mucoderm® (MD) tem sido amplamente utilizada como substituto do ETCS e tem alcançado resultados semelhantes. o MD tem a vantagem de disponibilidade que supera as limitações do sítio doador em enxertos autógenos. O objetivo deste estudo é investigar o uso do MD nos procedimentos de recobrimento radicular combinado com retalho extendido posicionado coronalmente (REPC), grupo teste (GT), em comparação ao ETCS associado ao REPC, grupo controle (GC). Dezoito pacientes adultos, apresentando recessão tipo 1 bilateral foram selecionados. Parâmetros clínicos, profundidade de sondagem, nível clínico de inserção, altura (RG) e largura (LRG) da retração, altura (GQ) e espessura (EGQ) da gengiva queratinizada e área da retração (ARG) foram registrados no início, 3 e 6 meses após os procedimentos cirúrgicos por um examinador cego. Aos 6 meses, um periodontista realizou uma Escala Estética de Recobrimento Radicular (ERR) (Cairo et al. 2009) analisando a posição da margem gengival (MG), contorno do tecido marginal (CTM), textura do tecido mole (TTM), alinhamento da junção mucogengival (AJG) e coloração da gengiva (CG). Aos 3 e 6 meses, um questionário estético funcional para o paciente foi utilizado para avaliar a satisfação com a taxa de recobrimento (STR), coloração da gengiva (CG) e sensibilidade dentinária (SEN), esta última aplicada também no baseline, e se necessário, voltaria a realizar a cirurgia (CIR) em outras áreas. O paciente respondeu ao questionário em uma escala VAS. O GT e o GC apresentaram redução significativa na média da RG (3,33 ± 0,89mm a 1,31 ± 1,03mm (p &lt0,05) e 3,21 ± 0,80mm a 0,83 ± 0,86mm ( p &lt0,05)), LRG (4,03 ± 0,57mm a 2,73 ± 1,62mm 12 e 4,10 ± 0,63mm a 2,07 ± 1,79mm (p &lt0,05)) e ARG (222638 ± 99731pix&sup2 para 72727 ± 82631pix&sup2 e 196461 ± 84815pix&sup2 para 48414 ± 63398pix&sup2 (p &lt0,05)) respectivamente e ganho de GQ (1,87 ± 1,17mm para 2,85 ± 1,43mm (p &lt0,05) e 1,91 ± 0 , 95mm a 2,83 ± 1,41mm (p &lt0,05)) e EGQ (0,76 ± 0,21mm a 1,10 ± 0,31mm (p &lt0,05) e 0,86 ± 0,39mm a 1, 36 ± 0,40mm (p &lt0,05)) respectivamente em um período de 6 meses. A quantidade média de cobertura radicular não foi diferente entre GT (61,33%) e GC (73,90%) (p&gt 0,05). Não houve diferença entre o GC e o GT nos parâmetros analisados no ERR aos 6 meses e para o questionário estético funcional ao paciente houve redução significativa no parâmetro SEN no GT (54,55 ± 32,60% para 19,11 ± 25,73% (p &lt0,05)) e GC (55,61 ± 30,88% a 11,17 ± 17,51% (p &lt0,05)). Ambos os grupos mostraram uma redução significativa na RG. Considerando-se que não foram observadas diferenças significativas entre o GC e o GT para RG, LRG, ARG e GQ e EGQ foram significativamente diferentes favorecendo GT, pode-se especular que o MD possa ser usado como alternativa ao CTG para o tratamento de recessões gengivais / Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix Mucoderm® (MD) has been widely used in periodontal and mucogingival surgery as a substitute for CTG and has achieved similar results. The MD has the advantage of availability overcoming the limitations of donor site in autograft. The aim of this study is to investigate the use of MD in root coverage procedures combined with extended coronally positioned flap (ECAF), test group (TG) in comparison to the CTG associated with the ECAF, control group (CG). Eighteen adult patients, non-smokers, presenting bilateral Cairo´s Recession Type 1 (RT1) were selected. Clinical parameters, probing depth, clinical attachment level, recession height (RH) and width (RW), keratinized tissue height (KTH) and thickness (KTT) and gingival recession área (GRA) were recorded at baseline,3 and 6 months after the surgical procedures by a blinded examiner. At 6 months a specialist in periodontics performed a Root Coverage Esthetic Score (RES) (Cairo et al. 2009) analyzing position of the gingival margin (GM), marginal tissue contour (MTC), soft tissue texture (STT), mucogingival junction alignment (MJA) and gingival color (GI). At 3 and 6 months a functional aesthetic questionnaire to the patient was used to evaluate the satisfaction with recovering rate (SRR), gingival color (GI) and dentin sensitivity (SEN) (the latter applied initially in the baseline) and, if necessary, would return to perform the surgery (SUR) in other areas. The patient answered the questionnaire on a VAS scale.The TG and CG showed a significant reduction in average for RH (3.33 ± 0.89mm to 1.31±1.03mm (p&lt0.05) and 3.21±0.80mm to 0.83±0.86mm (p&lt0.05)), RW (4.03±0.57mm to 2.73±1.62mm and4.10±0.63mm to 2.07±1.79mm (p&lt0.05)) and GRA (222638±99731pix&sup2 to 72727±82631pix&sup2 and 196461±84815pix&sup2 to 48414±63398pix&sup2 (p&lt0.05)) respectively and gain of KTH (1.87±1.17mm to 2.85±1.43mm (p&lt0.05) and 1.91±0.95mm to 2.83±1.41mm (p&lt0.05)) and KTT 14 (0.76±0.21mm to 1.10±0.31mm (p&lt0.05) and 0.86±0.39mm to 1.36±0.40mm (p&lt0.05)) respectively in a period of 6 month. The average amount of root coverage was not different between TG (61.33%) and CG (73.90%) (p&gt0.05). There was no differences between CG and TG on the parameters analyzed in the RES on 6 months and for the functional aesthetic questionnaire to the patient significant reduction was found on SEN parameter on TG (54.55±32,60% to 19.11±25.73% (p&lt0.05)) and CG (55.61±30.88% to 11.17±17.51% (p&lt 0.05)).In these 6 months follow up study, both groups showed a significant reduction in recession height. Considering no significant differences were observed between CG and TG for RH, RW, GRA and KTH and KTT were significant different favoring TG, it can be speculated that MD can be used as an alternative to CTG for the treatment of gingival recessions

A qualidade de uma reconstrução protética depende, primordialmente, de sua integração biológica e da sua adaptação. O afastamento gengival serve para se obter espaço para o material de moldagem e também para a visualização e acesso aos limites gengivais dos preparos, que são essenciais para a confecção de próteses com uma justeza de adaptação clínica. No entanto, a inserção de um material (fio retrator ou casquete) pode romper o sistema de fibras gengivais que conectam a margem gengival à superfície do cemento causando recessão gengival. Ocasionalmente, ocorre significativa inflamação ou perda de inserção. O objetivo deste trabalho foi quantificar a resposta inflamatória decorrente das diferentes técnicas de moldagem para prótese fixa, em termos da quantidade de IL-2, IL-4, IL-5, IL-10, TNF-α, IFN-γ, presentes no fluido gengival dos dentes com necessidade protética. A amostra foi composta por 10 dentes moldados pela técnica de afastamento gengival com fio retrator e um grupo de 10 dentes moldados pela técnica do casquete. Os pacientes foram selecionados considerando-se a necessidade de prótese parcial fixa, higiene bucal satisfatória e não possuírem sinais clínicos de doença periodontal. Previamente à moldagem, uma tira de periopaper foi inserida no sulco gengival do paciente e foi mantida por 30 segundos. A coleta foi repetida 4 vezes para as faces mesiovestibular, distovestibular, mesiolingual e distolingual. Terminado o procedimento da moldagem, após 2 horas, 4 horas e 24 horas, respectivamente, foi repetido o procedimento de inserção do periopaper nos 4 sítios dos dentes. A amostra foi preparada para a citometria de fluxo (CBA - cytometric beads array). Os resultados foram analisados pelo teste de Tukey. Na análise de variância a 3 critérios, por meio da comparação entre técnica de moldagem, paciente e tempo para os valores de TNF-α, a relação tempo e paciente versus tempo foi estatisticamente significante (p?0,05). Na comparação entre a técnica de moldagem com casquete e o fio retrator, não houve superioridade entre uma técnica e outra(p?0,05). O teste Tukey para a comparação intragrupo tempo (4 tempos), independente de técnica e paciente, mostrou relevância estatística entre os períodos antes da moldagem e após 24 horas (p=0,016) e, no período entre 2 horas e 24 horas após a moldagem (p=0,06). Portanto, foi possível concluir que não existe evidência científica que demonstre alguma superioridade das técnicas estudadas. Com isso, a escolha pelo método de afastamento gengival depende da situação clínica e habilidade do profissional. / The quality of a prosthetic reconstruction depends mostly on its integration and its biological adaptation. The gingival retraction serves to provide space for the impression material and also for visualize and give access to the gingival limit of tooth preparations, which are essential for making prostheses with a reliable clinical precision fit. However, the inclusion of a material (retractor cord or acrilic resin coping) can break the system of gingival fibers that connect the gingival margin to cementum´s surface, causing gingival recession. Occasionally, inflammation or significant insertion loss occurs. The aim of this study was to quantify the inflammatory response resulting from differents impression techniques for fixed prosthodontics in terms of the quantity of IL-2, IL-4, IL-5, IL-10, TNF-α, IFN-γ, found in gingival fluid of tooths needing prosthetic restorations. The sample consisted of 10 teeth impressed by gingival retraction cord technique and a group of 10 teeth using acrilic resin coping technique. Patients were selected considering the need for fixed partial denture, good oral hygiene and absence of periodontal disease´s clinical signs. Prior taking impressions, a Periopaper strip was inserted into the gingival sulcus of patients and was maintained for 30 seconds. The collect was repeated 4 times to the mesiobuccal, distovestibular, mesiolingual and distolingual sides: After the impression procedure, collecting was repeated after 2 hours, 4 hours and 24 hours respectively. the Periopaper strip was inserted on the teeth´s four sites. The sample was prepared for flow cytometry examination (CBA - cytometric beads array). The results were evalueted by Tukey test. The 3-way analysis of variance criteria,comparing impression technique, patient and time to values of TNF-α, the relationship between time and patient versus time was statistically significant (p ? 0.05). Comparing the acrilic resin coping and retraction cord impression techniques, there was no superiority between each other (p ? 0.05). The Tukey test for intragroup comparison time (4 times) irrespective of technique and patient showed statistical significance between periods before the impression and after 24 hours (p=0,016) and the period between 2 and 24 hours after impressions (p=0,06). Therefore, it was concluded that there is no scientific evidence that exists any superiority between the techniques studied. Thus, the choice of gingival retraction method depends on the clinical situation and professional´s skills.

L’actualité du droit de la consommation est aujourd’hui intrinsèquement marquée par le droit européen. Qu’il s’agisse du droit européen des contrats en général ou du droit européen de la consommation en particulier, la matière est au cœur d’une tension opposant les institutions communautaires qui, animées par la volonté de construire un Code civil européen couvrant le droit des contrats, de la responsabilité délictuelle, quasi-délictuelle et même la gestion d’affaires, sont confrontées aux craintes et réticences locales attachées à leurs spécificités. Le débat juridique analyse et évalue les impacts structurels et conjoncturels résultant de cette européanisation du droit de la consommation. Que celle-ci soit souhaitée ou subie, la réalité de l’évolution du contexte socio-économique ne permet plus aujourd’hui de faire l’économie d’une approche globale et de portée européenne, ne serait-ce qu’au regard de la nécessité de promouvoir et développer le marché intérieur. Le droit de la consommation représente la matière au carrefour d’intérêts divergents qu’il convient de concilier, d’où les propositions d’homogénéisation du droit au niveau européen, portant la promesse d’un droit homogène dont la lisibilité et l’accessibilité seraient le gage d’une protection efficiente du consommateur, acteur clé dans ce vaste processus. / Consumer protection law is inherently impacted by EU law. European contract law in general, and European consumer protection law specifically, are at the heart of tensions between EU institutions. Driven by a desire to create a European Civil Code covering contract law, tort and negligence law, and negotiorum gestio, EU institutions are confronted with fear and hesitation at the local level regarding their specific characteristics. The legal debate analyses and assesses the short-term and structural impacts resulting from the 'Europeanisation' of consumer protection law. Like it or not, socio-economic conditions are changing and we can no longer disregard a global and European approach, if only to promote and expand the internal European market. Consumer protection law is an area where opposing interests collide, and these should be reconciled. That's why there have been proposals to standardise law at the European level – to create a homogeneous group of laws that are clear and accessible and that would guarantee efficient protection for consumers, who are key to this whole process

If X is a simply connected CW complex, then it has a unique (up to isomorphism) minimal Sullivan model. There is an important rational homotopy invariant, called the rational Lusternik–Schnirelmann of X, denoted cat0(X), which has an algebraic formulation in terms of the minimal Sullivan model of X. We study another such numerical invariant called the rational retraction index of X, denoted r0(X), which is defined in terms of the minimal Sullivan model of X and satisfies 0 ≤ r0(X) ≤ cat0(X). It was introduced by Cuvilliez et al. as a tool to estimate the rational Lusternik–Schnirelmann category of the total space of a fibration. In this thesis we compute the rational retraction index on a range of rationally elliptic spaces, including for example spheres, complex projective space, the biquotient Sp(1) \ Sp(3) / Sp(1) × Sp(1), the homogeneous space Sp(3)/U(3) and products of these. In particular, we focus on formal spaces and formulate a conjecture to answer a question posed in the original article of Cuvilliez et al., “If X is formal, what invariant of the algebra H∗(X;Q) is r0(X)?”

The Meiolania platyceps is an extinct Meiolaniid turtle which resided in the Southern Hemispheres Gondwanaland regions. The specimen used for this project was from the Pleistocene and found on Lord Howe Island, Australia. The aim of the project was to study the neck vertebrae in order to determinethe feeding ecology of the species, whether it preferred finding food of the ground or from higher vegetation. Through the neck range of motion, information about the relationships of the species should also be found, this since both taxonomic suborders of turtles, the cryptodira and he pleurodira have very distinctive patterns of movement for retracting the head. To determine this, the method of photogrammetry was used to develop 3D models of the vertebrae that could be manipulated in order to determine range of motion of the neck. The neck was discovered to match neither the movement pattern of the cryptodira or the pleurodira but is more likely a form of stem turtle or stem crypodira. Regarding the feeding patterns the results proved more conclusive. The neck mobility seems to strongly favor feeding from the ground. Since the Meiolania platyceps remnants have been found on islands and dated to Pleistocene time, which was the time leading up to the latest iceage, these ground level eating habits would most likely favor a diet of grass or similar. / Meiolania platyceps är en utdöd Meiolaniid sköldpadda som levde på södra halvklotets Gondwanaland regioner. Skelettet som används för detta projekt var från pleistocen tid och hittades på Lord Howe Island i Australien. Syftet med projektet var att studera halskotorna för att avgöra ätmönstret för arten, huruvida födointag kom från marken eller från högre vegetation. Genom nackens rörlighet kommer även mer information om artens släktskap kunna fås eftersom båda underarterna av sköldpadda har tydliga rörelsemönster för att dra tillbaka huvudet under skalet. För att fastställa detta användes metoden fotogrammetri för att utveckla 3D-modeller av kotor som kunde manipuleras för att fastställa halsens rörlighet. Baserat på halsens rörelseförmåga verkar arten inte passa in på varken cryptodira eller pleurodira utan det är troligare att arten är en form av stam sköldpadda eller en stam cryptodira. För födovanorna var dock studien mer konklusiv. Nackens rörlighet verkar tydligt tyda på att arten föredrog att få sin föda från på eller nära marknivå. Då Meiolania platyceps återfunnits på öar och skeletten daterats till pleistocen tid, som var upptakten till den senaste istiden, känns det troligt att markätande födovanor tyder på en kosthållning som främst bestod av gräs eller dylikt.