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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Percurso da Aquisição dos Encontros Consonantais, Fonemas e Estruturas Silábicas em Crianças de 2:1 a 3:0 anos de idade / Course of Acquisition of Consonantal Clusters, Phonemes and Syllabic Structures in Children from 2:1 to 3:0 years old

Daniela Evaristo dos Santos Galea 03 April 2008 (has links)
O objetivo geral do estudo foi descrever o percurso da aquisição dos encontros consonantais, fonemas e estruturas silábicas em crianças de 2:1 a 3:0 anos de idade. Foram sujeitos da pesquisa 88 crianças divididas de acordo com a idade e o sexo: GI composto de dois grupos de crianças de 2:1 a 2:6 anos de idade, GI F 23 meninas e GI M 18 meninos e, GII composto de dois grupos de 2:7 a 3:0 anos de idade, GII F 24 meninas e GII M - 24 meninos. Todas as crianças freqüentavam creches conveniadas à Prefeitura do Município de São Paulo e não apresentavam queixa de problema de linguagem, mais de três ocorrências de otite média e não eram bilíngües. A coleta de dados foi realizada por meio de três provas de fonologia: nomeação, imitação e fala espontânea. Todas as provas foram registradas em vídeo e audio. Os resultados mostraram que não havia diferença entre as posições de sílabas para encontros consonantais, mas em relação aos fonemas e estruturas silábicas foi encontrada diferença estatística em algumas situações. A comparação entre meninos e meninas da mesma faixa etária não mostrou diferença; assim, foram criados dois grupos: GI (2:1 a 2:6 anos) e GII (2:7 a 3:0 anos). Os resultados mostraram que com o aumento da idade, houve melhora no desempenho de acertos totais em encontros consonantais, fonemas e estruturas silábicas em algumas posições de sílabas. Tal fato também foi observado ao analisar cada um dos encontros consonantais, fonemas e estruturas silábicas. As diferenças foram encontradas para: /f/, /k/, /d/, /b/, /m/, /z/, /s/, /f/, //, //, /n/, /l/, //, /X/, arquifonema /S/ e /R/, estrutura CV em trissílabos, CCV em dissílabos e CVC em dissílabos e trissílabos em determinadas posições de sílabas e provas. Alguns alvos foram mais omitidos, como o fonema /X/ e arquifonemas /S/ e /R/. Os demais tiveram mais substituições. Já as fricativas /s/ e /z/, as plosivas linguodentais e as líquidas também apresentaram distorções acústicas e articulatórias. A estrutura silábica CCV apresentou com maior freqüência a omissão da segunda líquida, a CV omissão de fonema e de sílaba e a CVC, omissão do arquifonema. Não houve diferença entre o /s/ em onset e coda de sílaba, com exceção do GII na sílaba final da imitação. Porém, as crianças apresentaram melhor desempenho do // em onset que em coda. Quanto ao critério de aquisição, os encontros consonantais, fonemas e estruturas silábicas foram classificados como: não adquirido, em aquisição, produção habitual e adquirido. Até os 3:0 anos os fonemas /p/, /b/, /t/, /d/, /k/, /f/, /m/, /n/, //, /l/, /g/, /X/ e arquifonema /S/ estão adquiridos em pelo menos uma posição de sílaba. A estrutura CV também está adquirida nesta faixa etária. A comparação entre as provas indicou que as crianças não mostraram desempenho diferente nas provas quanto aos encontros consonantais e estruturas CCV. Nas demais análises, os fonemas e estruturas silábicas apresentaram, em muitos momentos, diferenças entre as provas ao se verificar as posições das sílabas. / The general purpose of this study was to describe the course of acquisition of consonantal clusters, phonemes and syllabic structure in children from 2:1 to 3:0 years old. The subjects of the research were 88 children divided according to age and gender: GI was composed of two groups of children from 2:1 to 2:6 years old, GIF: 23 girls and GI-M: 18 boys and, GII composed of 2 groups from 2:7 to 3:0 years old, GII-F: 24 girls and GII-M: 24 boys. All children attended public day care centers linked to the São Paulo town hall and they did not have any language problems, more than three otitis media episodes, nor they were bilingual. Data collection was done through three phonology tests: picture naming, imitation and spontaneous speech. All the tests were recorded with a camera and a tape recorder. Results showed no differences between syllables in relation to consonantal clusters, although some differences were found regarding phonemes and syllabic structures. The comparison between girls and boys of the same age range did not show differences, thus, two groups were formed: GI (2:1 to 2:6 years) e GII (2:7 to 3:0 years). The results indicated that with the age growth, there was a better performance related to the correct production of consonantal clusters, phonemes and syllabic structures, in some syllables. This was also detected when analyzing each consonantal cluster, phoneme and syllabic structure separately. Differences were found for: /f/, /k/, /d/, /b/, /m/, /z/, /s/, /f/, //, //, /n/, /l/, //, /X/, archiphonemes /S/ and /R/, CV structure in trisyllabic words, CCV structure in dissylabic words and CVC structure in trisyllabic and dissylabic words, in some syllables and tests. Some targets were more omitted like the /X/ phoneme and the archiphonemes /S/ and /R/; the others were more substituted. The fricatives /s/ and /z/, the dental plosives and the liquids also showed acoustical and articulatory distortions. The CCV syllable presented more omission of the liquid, the CV syllable more phoneme omission and the CVC syllable more omission of the archiphoneme. There was no difference between the /s/ in the onset and coda position of the syllable, with the exception of the final syllable of the imitation test in the GII. However, children presented a better performance of the /R/ in the onset than in the coda of the syllable. The consonantal clusters, phonemes and syllabic structures were classified as the following criteria of acquisition: not acquired, in acquisition, customary production and acquired. Until the age of 3:0, the phonemes /p/, /b/, /t/, /d/, /k/, /f/, /m/, /n/, //, /l/, /g/, /X/ and the archiphoneme /S/ were acquired in at least one syllable within the word. Also, the CV syllable was already acquired at that time. Comparison between tests indicated that children did not show different performance related to consonantal clusters and CCV syllable between them. On the other hand, phonemes and other syllabic structures showed differences within the tests according to some syllables of the word.
12

Könshomogena arbetsgrupper på gott och ont : enkätstudie av kvinnors hälsa på arbetsplatsen / <em></em> : <em></em>

Friberg, Alexandra, Tibell, Louise January 2009 (has links)
<p>Idag satsas det inom folkhälsoarbetet mycket på arbetsplatsen som arena då arbetslivet har en avgörande betydelse för att varje människa ska uppnå god hälsa. Vad som gör en arbetsplats hälsosam är individuellt. För många handlar det dock om att känna eget ansvar, delaktighet, inflytande, gemenskap och meningsfullhet. Den svenska arbetsmarknaden karaktäriseras av att män och kvinnor arbetar inom olika sektorer och yrkesområden, vilket har skapat en könssegregerad arbetsmarknad. Den könssegregerade arbetsmarknaden leder till att arbetsgrupperna på arbetsplatserna ofta är könshomogena. Arbetsgruppen har en betydande roll för att individen ska kunna utvecklas som person, känna social trygghet och gemenskap.</p><p> </p><p>Det finns inte mycket litteratur som påpekar förhållandet mellan hälsa och arbetsgruppens könsammansättning med fokus på upplevd fysisk och psykisk hälsa och lärande. Syftet med studien var att undersöka om det förekommer skillnader bland kvinnor som arbetar med mestadels kvinnor jämfört med kvinnor som arbetar med mestadels män, utifrån ett hälso- och lärandeperspektiv. Studien gjordes med kvantitativ metod och enkäter användes som datainsamlingsmetod. Undersökningsgruppen var kvinnor som arbetar på mansdominerade samt kvinnodominerade arbetsplatser. Sammanlagt delades 200 enkäter ut, 100 till respektive typ av arbetsplats. Den slutgiltiga svarsfrekvensen blev 83,5%.</p><p> </p><p>Resultatet visar att kvinnorna på den kvinnodominerade arbetsplatsen ansåg att delaktigheten, inflytandet och lärandet på arbetet och i arbetsgruppen var bättre i jämförelse med vad kvinnorna på de mansdominerade arbetsplatserna ansåg. Kvinnorna på de mansdominerade arbetsplatserna ansåg att de blev mer granskade än männen samt att olika beteenden som påverkade trivseln negativt förekom i större utsträckning än vad kvinnorna på den kvinnodominerade arbetsplatsen ansåg. För att förverkliga visionen om den hälsosamma arbetsplatsen behöver vi genomföra ett förändringsarbete där människor har möjlighet till inflytande och görs delaktiga i förändringsprocesser.</p> / <p>The public health work of today is characterized by large investments in the workplace because of its importance for the possibility of the individual to reach good health. What makes the workplace healthy is individual, but for most of us it depends on participation, responsibility, influence, togetherness and meaningfulness. The Swedish labour market is very sex segregated in terms of men and women working with different occupations. Workgroups therefore often consist predominantly of either  men or women. The workgroup has an important role for the individual to feel social security and togetherness and to grow as a person.</p><p>There is not much written about the relationship between health and the sex distribution of a workgroup with focus on the physical and mental health and learning. The aim of the study was to investigate if there were any differences between women who work mostly with women and women who work mostly with men, from a health and learning perspective. The study is quantitative and questionnaires were used to collect data. The study population are women who work on a male-dominated or female-dominated workplaces. A total of 200 questionnaires were distributed, 100 to each type of workplace. The finale rate of response was 83,5%.</p><p>The result shows that women on the female-dominated workplace felt that participation, influence and learning at work and in the workgroup were better in comparison with what the women on the male-dominated workplace felt. The women on the male-dominated workplace thought that they got more inspected than the men, at work. To actualize the vision about healthy workplaces we need to promote the process of change where people have the possibility to influence and participate in the process.</p>
13

Pre-school Teachers’ Perceived Control and Behaviour Problems in Children

Hammarberg, Annie January 2003 (has links)
<p>In this thesis, pre-school teachers’ perceived control, is examined in relation to problem behaviours of children and the actions of teachers in the classroom. In addition, other factors that are thought to relate to teachers’ perceived control were studied.</p><p>The results of <i>Study I </i>indicate that pre-school teachers’ high perceived control was related to high intentions to act in the event of child behaviour problems. Teachers’ high satisfaction with their work was also related to high perceived control. <i>Study II </i>showed that low perceived control was associated with having a high proportion of children with a high level of externalising behaviours and of boys in the classroom. <i>Study III </i>shows that children who had a high level of externalising behaviours at the beginning and throughout the school year had teachers with low perceived control. Teachers’ perceived control was not related to their perception of internalising behaviours in the same way as to externalising behaviours and it was unrelated to a change in any direction of problem behaviours. Concerning changes in problem behaviours, no other factor was found, except a low child to adult ratio for a positive change of internalising behaviours. In <i>Study IV</i>, the aim was to examine naturally occurring child–teacher interactions. Teachers’ responding with commands to children was associated with teachers’ low perceived control, whereas restrictive teacher responses were not related to teachers’ perceived control.</p><p>The present study indicates that teachers’ perceptions of children are important for their perceived control. It provides evidence that teachers’ low perceived control is associated with their difficulties in handling externalising behaviours and the behaviour of the boys in the classroom. Responding to problem behaviours can be explained by teachers’ perceived control, and their perception of a child’s sex and externalising behaviours.</p>
14

Pre-school Teachers’ Perceived Control and Behaviour Problems in Children

Hammarberg, Annie January 2003 (has links)
In this thesis, pre-school teachers’ perceived control, is examined in relation to problem behaviours of children and the actions of teachers in the classroom. In addition, other factors that are thought to relate to teachers’ perceived control were studied. The results of Study I indicate that pre-school teachers’ high perceived control was related to high intentions to act in the event of child behaviour problems. Teachers’ high satisfaction with their work was also related to high perceived control. Study II showed that low perceived control was associated with having a high proportion of children with a high level of externalising behaviours and of boys in the classroom. Study III shows that children who had a high level of externalising behaviours at the beginning and throughout the school year had teachers with low perceived control. Teachers’ perceived control was not related to their perception of internalising behaviours in the same way as to externalising behaviours and it was unrelated to a change in any direction of problem behaviours. Concerning changes in problem behaviours, no other factor was found, except a low child to adult ratio for a positive change of internalising behaviours. In Study IV, the aim was to examine naturally occurring child–teacher interactions. Teachers’ responding with commands to children was associated with teachers’ low perceived control, whereas restrictive teacher responses were not related to teachers’ perceived control. The present study indicates that teachers’ perceptions of children are important for their perceived control. It provides evidence that teachers’ low perceived control is associated with their difficulties in handling externalising behaviours and the behaviour of the boys in the classroom. Responding to problem behaviours can be explained by teachers’ perceived control, and their perception of a child’s sex and externalising behaviours.
15

Könshomogena arbetsgrupper på gott och ont : enkätstudie av kvinnors hälsa på arbetsplatsen / :

Friberg, Alexandra, Tibell, Louise January 2009 (has links)
Idag satsas det inom folkhälsoarbetet mycket på arbetsplatsen som arena då arbetslivet har en avgörande betydelse för att varje människa ska uppnå god hälsa. Vad som gör en arbetsplats hälsosam är individuellt. För många handlar det dock om att känna eget ansvar, delaktighet, inflytande, gemenskap och meningsfullhet. Den svenska arbetsmarknaden karaktäriseras av att män och kvinnor arbetar inom olika sektorer och yrkesområden, vilket har skapat en könssegregerad arbetsmarknad. Den könssegregerade arbetsmarknaden leder till att arbetsgrupperna på arbetsplatserna ofta är könshomogena. Arbetsgruppen har en betydande roll för att individen ska kunna utvecklas som person, känna social trygghet och gemenskap.   Det finns inte mycket litteratur som påpekar förhållandet mellan hälsa och arbetsgruppens könsammansättning med fokus på upplevd fysisk och psykisk hälsa och lärande. Syftet med studien var att undersöka om det förekommer skillnader bland kvinnor som arbetar med mestadels kvinnor jämfört med kvinnor som arbetar med mestadels män, utifrån ett hälso- och lärandeperspektiv. Studien gjordes med kvantitativ metod och enkäter användes som datainsamlingsmetod. Undersökningsgruppen var kvinnor som arbetar på mansdominerade samt kvinnodominerade arbetsplatser. Sammanlagt delades 200 enkäter ut, 100 till respektive typ av arbetsplats. Den slutgiltiga svarsfrekvensen blev 83,5%.   Resultatet visar att kvinnorna på den kvinnodominerade arbetsplatsen ansåg att delaktigheten, inflytandet och lärandet på arbetet och i arbetsgruppen var bättre i jämförelse med vad kvinnorna på de mansdominerade arbetsplatserna ansåg. Kvinnorna på de mansdominerade arbetsplatserna ansåg att de blev mer granskade än männen samt att olika beteenden som påverkade trivseln negativt förekom i större utsträckning än vad kvinnorna på den kvinnodominerade arbetsplatsen ansåg. För att förverkliga visionen om den hälsosamma arbetsplatsen behöver vi genomföra ett förändringsarbete där människor har möjlighet till inflytande och görs delaktiga i förändringsprocesser. / The public health work of today is characterized by large investments in the workplace because of its importance for the possibility of the individual to reach good health. What makes the workplace healthy is individual, but for most of us it depends on participation, responsibility, influence, togetherness and meaningfulness. The Swedish labour market is very sex segregated in terms of men and women working with different occupations. Workgroups therefore often consist predominantly of either  men or women. The workgroup has an important role for the individual to feel social security and togetherness and to grow as a person. There is not much written about the relationship between health and the sex distribution of a workgroup with focus on the physical and mental health and learning. The aim of the study was to investigate if there were any differences between women who work mostly with women and women who work mostly with men, from a health and learning perspective. The study is quantitative and questionnaires were used to collect data. The study population are women who work on a male-dominated or female-dominated workplaces. A total of 200 questionnaires were distributed, 100 to each type of workplace. The finale rate of response was 83,5%. The result shows that women on the female-dominated workplace felt that participation, influence and learning at work and in the workgroup were better in comparison with what the women on the male-dominated workplace felt. The women on the male-dominated workplace thought that they got more inspected than the men, at work. To actualize the vision about healthy workplaces we need to promote the process of change where people have the possibility to influence and participate in the process.
16

Det bästa av två världar : Könsfördelningen inom Human Resources branschen utifrån det mjuka och hårda HRM-perspektivet

Heldring, Josefine January 2013 (has links)
Human Resources (en benämning för personalarbetet) är ett yrke som idag blir allt populärare. Trots detta visar statistik att en majoritet av kvinnor både studerar och arbetar med personalfrågor. Studien har därför som syfte att undersöka varför Human Resources branschen har en ojämn könsfördelning. Detta görs genom en historisk inblick i branschens utveckling i relation till samhällets förändringar, där en analys av texter ger en bild av dagens personalarbete. De teoretiska utgångspunkterna består dels av socialkonstruktivism och dels av begreppen mjuk och hård Human Resources Management. Det mjuka begreppet förknippas med kvinnlighet, medan det hårda begreppet framhäver en manlig bild av yrket. Undersökningen kommer fram till att historiskt har främst det mjuka begreppet varit i fokus, men det hårda perspektivet har gjort framsteg de senast årtiondena och framhävs idag lika mycket som det mjuka. Utöver detta visar även studien på att könsfördelningen kan komma att förändras i framtiden om den utvecklingstendens som finns idag fortsätter. Yrket får allt mer status, inflytande och makt samtidigt som den hårda bilden av yrket framhävs allt mer. Dessa aspekter förknippas, enligt forskning, oftast med män. Dessvärre visar inte högskoleutbildningarna inom personalvetenskap på samma förändring, utan dessa domineras fortfarande av kvinnor. Det behövs därför ett aktivt arbete med könsfördelningen om en jämn könsfördelning ska uppnås.
17

Uticaj pola, težine i dužine trajanja oboljenja na kontaktnu senzibilizaciju kod obolelih od vulgarne psorijaze / The influence of sex, severity and duration of disease on contact sensitization in patients with psoriasis vulgaris

Petrović Aleksandra 05 February 2015 (has links)
<p>Kontaktna senzibilizacija, kao stanje specifične reaktivnosti kože, može biti egzogeni pokretač psorijaze. Rezultat je interakcije endogenih i egzogenih činioca. Jedan od najznačajnijih endogenih faktora kome se pripisuje uloga faktora rizika jeste pol. Cilj istraživanja bio je da se kod obolelih od psorijaze utvrdi učestalost i distribucija kontaktne senzibilizacije u odnosu na pol, razlike u distribuciji kontaktne senzibilizacije po polu&nbsp; između osoba obolelih od psorijaze i osoba pod sumnjom na postojanje kontaktnog alergijskog dermatitisa, povezanost kontaktne senzibilizacije i težine kliničkog nalaza i povezanost kontaktne senzibilizacije i dužine trajanja oboljenja. Hipoteza istraživanja polazila je od pretpostavke da je kontaktni alergijski dermatitis redak kod obolelih od psorijaze, jer hronična inflamacija u koži smanjuje njenu sposobnost specifične senzibilizacije a da je veća učestalost kontaktne senzibilizacije kod osoba ženskog pola rezultat egzogenog faktora tj.ekspozicije, kao i da je učestalost kontaktne senzibilizacije u pozitivnoj korelaciji sa težinom i dužinom trajanja oboljenja. Istaživanje je sprovedeno kod 176 ispitanika koji su bili podeljeni u dve grupe. Eksperimentalnu grupu su činili oboleli od psorijaze, a kontrolnu grupu ispitanici upućeni na alergolo&scaron;ko testiranje pod sumnjom na postojanje kontaktnog alergijskog dermatitisa. Obolelima od psorijaze je ocenjivana težine oboljenja PASI skorom, a svi ispitanici bili su alergolo&scaron;ki testirani epikutanim -pač testom. Pozitivni rezultati alergolo&scaron;kog testiranja su analizirani, u cilju utvrđivanja kliničke relevantnosti istih. Ispitanicima u grupi obolelih od psorijaze je testom skarifikacije određivano prisustvo ili odsustvo Koebnerovog izomorfnog podražajnog fenomena. Istraživanjem je utvrđeno, da se kontaktno reagovanje kod obolelih od psorijaze na najmanje jedan standardni alergen nije statistički značajno razlikovalo od reagovanja osoba kod kojih je postavljena sumnja na postojanje kontaktnog alergijskog dermatitisa, ali je senzitivnost izražena kroz prosečan broj pozitivnih testova po jednom ispitaniku bila statistički značajno niža kod obolelih od psorijaze. Poređenjem kontaktnog reagovanja mu&scaron;karaca i žena nisu utvrđene značajna razlike u reagovanju u odnosu na pol. Težina oboljenja nije uticala na učestalost kontaktne senzibilizacije kod obolelih od psorijaze, ali je učestalost kontaktne senzibilizacije bila u pozitivnoj korelaciji sa dužinom trajanja bolesti. Niža stopa kontaktnog reagovanja utvrđena je kod osoba obolelih od psorijaze koji su imali pozitivan Koebnerov fenomen u trenutku ispitivanja.</p> / <p>Contact sensitization as a state of specific skin reactivity may provoke psoriasis resulting from an interaction between extrinsic and intrinsic factors. One of the most significant factors characterized, as a risk factor, is the sex. The aim of this study was to determinate the frequency and distribution of contact sensitization in patients with&nbsp; psoriasis with respect to their sex, as well as the differences in the distribution of contact sensitization in both sexes, namely&nbsp; with patients with psoriasis and patients&nbsp; suspected to allergic contact dermatitis. Consequently, appropriate attention was paid to the correlation between contact sensitization and disease severity, and between contact sensitization and disease duration. Hypothesis were based on the assumption that allergic contact dermatitis is rare in&nbsp; patients with psoriasis, as a chronic inflammation of the skin reduces its ability specific sensitization, as well as that the higher frequency of contact sensitization in females represent a result of exogenous factors, i.e. exposition, and finally that there is a positive correlation between the incidence of contact sensitization and the disease severity, and contact sensitization and the disease duration. The study included 176 patients. They were divided into two groups: the study group included patients with psoriasis, while the control group included patients referred for allergy testing, since they were suspected to allergic contact dermatitis. The severity of psoriasis was evaluated by PASI score. Thereafter,&nbsp; each patient underwent patch testing. The positive results of patch tests were evaluated with the aim to define their clinical relevancy. Subjects from the group of psoriatic patients passed scarification test carried out to indicate the presence or absence of K&ouml;ebner isomorphic phenomenon. This research led us to the conclusion that the positive reaction of psoriatic patients to at least one standard allergen did not indicate a statistically significant different reaction when compared to the reaction of patients suspected to allergic contact dermatitis. From the other side, the sensitivity expressed through the average number of positive&nbsp; tests per one&nbsp; tested&nbsp; patients was&nbsp; significantly lower in&nbsp; patients&nbsp; with psoriasis. Comparison of the contact response of men and women showed no significant differences in response with respect to&nbsp; their sex. The&nbsp; disease severity did not influence the frequency of contact sensitization in patients&nbsp; with&nbsp; psoriasis. At&nbsp; the same time, the frequency of contact sensitization stood in a positive correlation with the duration of disease. The lower rate of contact sensitization was found in patients with psoriasis who have had a&nbsp; positive K&ouml;ebner phenomenon at&nbsp; the time of testing.</p>
18

Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One.

Asher, M Innes, Stewart, Alistair W, Mallol, Javier, Montefort, Stephen, Lai, Christopher K W, Aït-Khaled, Nadia, Odhiambo, Joseph, Chiarella, Pascual, The ISAAC Phase One Study Group 21 January 2010 (has links)
Revisión por pares
19

"Estudo epidemiológico descritivo dos doentes de melanoma cutâneo acompanhados na Unidade de Melanoma da Santa Casa de São Paulo" / Descriptive epidemiological study in cutaneous melanoma patients followed at Melanoma Unit of Santa Casa de São Paulo.

Ferrari Junior, Nelson Marcos 30 August 2006 (has links)
INTRODUÇÃO: O melanoma cutâneo constitui cerca de 3% de todos os tumores da pele. Atinge indivíduos jovens com média de idade de aparecimento entre 50 e 58 anos. Em torno de 20% dos doentes apresentarão doença avançada e morrerão antes de completar cinco anos de sobrevida. CASUÍSTICA E MÉTODOS: Neste estudo retrospectivo de 364 casos acompanhados de maio de 1993 a janeiro de 2006 descreveram-se as variáveis: sexo, idade, cor, localização da lesão primária, tipo de crescimento, espessura de Breslow, nível de Clark, presença de ulceração, estadiamento e suas correlações. RESULTADOS: Predominou o sexo feminino (58,8%) resultando em uma proporção de 1,4 mulheres para cada homem. A média das idades dos pacientes foi de 58,9 anos e a mediana de 61,0 anos. Pacientes não-brancos constituíram 13,7% da amostra. Para homens e mulheres o melanoma cutâneo localizou-se, predominantemente no tronco (24,3-38,0%) e pés (21,4-23,9%). O melanoma acrolentiginoso representou 22,3% de toda amostra. Os padrões melanoma expansivo superficial e melanoma nodular (p < 0,001) e lesões no tronco (52,8%) predominaram nos indivíduos brancos. O melanoma acrolentiginoso (64%) e a localização nos pés (68,2%)prevaleceram nos pacientes não-brancos. Observou-se minoria de casos com lesão primária in situ (14,6%- EC 0) e alto percentual de melanoma cutâneo espesso (39,7% > 4,0 mm). Presença de ulceração foi observada em 13,4% para tumores finos (= 1,0 mm). Homens apresentaram lesões mais espessas (p = 0,011) e ulceradas (p < 0,001) em relação às mulheres, assim como idosos em relação à não idosos (p = 0,021 para a espessura e p = 0,015 para ulceração). A sobrevida média para os pacientes com doença localizada foi de 97,8 meses e a taxa de sobrevida específica para melanoma cutâneo foi de 85,1% em três anos. CONCLUSÕES: Esta amostra constituiu-se de pacientes com tumores espessos e ulcerados denotando diagnóstico tardio do melanoma cutâneo e pior prognóstico. Caracterizou-se por apresentar predomínio de mulheres, de pacientes não-brancos, de lesões nas extremidades e de melanoma acrolentiginoso. / INTRODUCTION: Cutaneous melanoma represents around 3% of all skin tumors. Affecting young patients, with mean age between 50 and 58 years old. About 20% of the patients will have advanced disease and will die before five years of survival. CASUISTIC AND METHODS: In this retrospective study of 364 cases recorded from May 1993 to January 2006 at the Melanoma Unit of Santa Casa de São Paulo the following variables were described: sex, age, skin color, tumor site, growth pattern, tumor thickness, Clark level, ulceration, staging and their correlations. RESULTS: Female (58,8%) prevailed resulting in 1,4 women for each man. The mean age of the patients was 58,9 years old and the median, 61,0 years old. Non-white patients were 13,7% of the sample. The anatomic site of cutaneous melanoma on men and women prevailed at trunk (24,3 – 38,0%) and feet (21,4 – 23,9%). Acral entiginous melanoma represented 22,3% of the cohort. Superficial expansive melanoma and nodular melanoma patterns (p<0,001) and trunk lesions (52,8%) predominated on white patients. Acral lentiginous melanoma (64%) and feet anatomic site 68,2%) prevailed on non-white patients. In situ primary lesions were observed in few cases (14,6% - EC 0) and there was high percentage of thick cutaneous melanoma (39,7% > 4,0 mm). In thin tumors (=1,0 mm) were found 13,4% of ulceration. Thickener (p = 0,011) and ulcerated lesions (p < 0,001) were found more in male and in elderly patients (p = 0,021 for thickeness and p = 0,015 for ulceration). The mean survival of patients with local disease was 97,8 months and the three-year survival rate for cutaneous melanoma was 85,1%. CONCLUSIONS: The cohort consisted mostly of thick and ulcerated tumors, which meant late diagnosis and bad prognosis. Also distinguished by considerable prevalence of female, non-white patients, limb lesions and acral lentiginous melanoma.
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Atypical depression, body mass, and left vetricular mass analysis of data from CARDIA /

Schwartz, Sari D. January 2005 (has links) (PDF)
Thesis (M.S.)--Uniformed Services University of the Health Sciences, 2005. / Typescript (photocopy).

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