Les enfants d’âge préscolaire (≤ 5 ans) sont plus à risque de subir un traumatisme crânio-cérébral (TCC) que les enfants plus agés, et 90% de ces TCC sont de sévérité légère (TCCL). De nombreuses études publiées dans les deux dernières décennies démontrent que le TCCL pédiatrique peut engendrer des difficultés cognitives, comportementales et psychiatriques en phase aigüe qui, chez certains enfants, peuvent perdurer à long terme. Il existe une littérature florissante concernant l'impact du TCCL sur le fonctionnement social et sur la cognition sociale (les processus cognitifs qui sous-tendent la socialisation) chez les enfants d'âge scolaire et les adolescents. Or, seulement deux études ont examiné l'impact d'un TCCL à l'âge préscolaire sur le développement social et aucune étude ne s'est penchée sur les répercussions socio-cognitives d'un TCCL précoce (à l’âge préscolaire). L'objectif de la présente thèse était donc d'étudier les conséquences du TCCL en bas âge sur la cognition sociale. Pour ce faire, nous avons examiné un aspect de la cognition sociale qui est en plein essor à cet âge, soit la théorie de l'esprit (TE), qui réfère à la capacité de se mettre à la place d'autrui et de comprendre sa perspective. Le premier article avait pour but d'étudier deux sous-composantes de la TE, soit la compréhension des fausses croyances et le raisonnement des désirs et des émotions d'autrui, six mois post-TCCL. Les résultats indiquent que les enfants d'âge préscolaire (18 à 60 mois) qui subissent un TCCL ont une TE significativement moins bonne 6 mois post-TCCL comparativement à un groupe contrôle d'enfants n'ayant subi aucune blessure. Le deuxième article visait à éclaircir l'origine de la diminution de la TE suite à un TCCL précoce. Cet objectif découle du débat qui existe actuellement dans la littérature. En effet, plusieurs scientifiques sont d'avis que l'on peut conclure à un effet découlant de la blessure au cerveau seulement lorsque les enfants ayant subi un TCCL sont comparés à des enfants ayant subi une blessure n'impliquant pas la tête (p.ex., une blessure orthopédique). Cet argument est fondé sur des études qui démontrent qu'en général, les enfants qui sont plus susceptibles de subir une blessure, peu importe la nature de celle-ci, ont des caractéristiques cognitives pré-existantes (p.ex. impulsivité, difficultés attentionnelles). Il s'avère donc possible que les difficultés que nous croyons attribuables à la blessure cérébrale étaient présentes avant même que l'enfant ne subisse un TCCL. Dans cette deuxième étude, nous avons donc comparé les performances aux tâches de TE d'enfants ayant subi un TCCL à ceux d'enfants appartenant à deux groupes contrôles, soit des enfants n'ayant subi aucune blessure et à des pairs ayant subi une blessure orthopédique. De façon générale, les enfants ayant subi un TCCL ont obtenu des performances significativement plus faibles à la tâche évaluant le raisonnement des désirs et des émotions d'autrui, 6 mois post-blessure, comparativement aux deux groupes contrôles. Cette étude visait également à examiner l'évolution de la TE suite à un TCCL, soit de 6 mois à 18 mois post-blessure. Les résultats démontrent que les moindres performances sont maintenues 18 mois post-TCCL. Enfin, le troisième but de cette étude était d’investiguer s’il existe un lien en la performance aux tâches de TE et les habiletés sociales, telles qu’évaluées à l’aide d’un questionnaire rempli par le parent. De façon intéressante, la TE est associée aux habiletés sociales seulement chez les enfants ayant subi un TCCL. Dans l'ensemble, ces deux études mettent en évidence des répercussions spécifiques du TCCL précoce sur la TE qui persistent à long terme, et une TE amoindrie seraient associée à de moins bonnes habiletés sociales. Cette thèse démontre qu'un TCCL en bas âge peut faire obstacle au développement sociocognitif, par le biais de répercussions sur la TE. Ces résultats appuient la théorie selon laquelle le jeune cerveau immature présente une vulnérabilité accrue aux blessures cérébrales. Enfin, ces études mettent en lumière la nécessité d'étudier ce groupe d'âge, plutôt que d'extrapoler à partir de résultats obtenus avec des enfants plus âgés, puisque les enjeux développementaux s'avèrent différents, et que ceux-ci ont potentiellement une influence majeure sur les répercussions d'une blessure cérébrale sur le fonctionnement sociocognitif. / Preschool children (≤ 5 years old) are at particular risk of sustaining traumatic brain injury (TBI) and 90% of these injuries are mild in nature (mTBI). A substantial amount of research has provided evidence of acute and, in more isolated cases, long-term cognitive, behavioral, and psychiatric consequences following mTBI. In the last two decades, there has been an increase in scientific attention dedicated to the social and socio-cognitive (the cognitive functions that underpin socialisation) sequelae of pediatric mTBI; however, research has almost exclusively been conducted with school-aged children and adolescents. Thus, the literature concerning the social repercussions of mTBI remains comparatively sparse in preschool children, with only two studies that have examined social competence following mTBI. No study has investigated the consequences of early (preschool) mTBI on social cognition. Therefore, the overall objective of this thesis was to expand our understanding of the impact of preschool mTBI on social cognition. More specifically, we addressed an aspect of social cognition that typically emerges during the preschool years, that of theory of mind (ToM), known as the capacity to put oneself in others’ shoes and understand their perspective. The first article examined two subcomponents of ToM, that of false belief understanding and desires and emotions reasoning, 6 months post-mTBI. The findings indicate that preschool children (18 to 60 months) who sustain mTBI have significantly poorer ToM skills compared to typically developing peers 6 months post-injury. The second article focused on the debate in the mTBI literature concerning the most appropriate control group for isolating outcomes that are specific to brain injury. Indeed, it is argued that the choice of the control group (community controls vs. injured counterparts) is of paramount importance because it dictates the conclusions that can be drawn in TBI research. It is argued that brain-injury-specific effects constitute a valid conclusion only when compared to injured peers because in general, children who sustain accidental injuries (whether orthopedic or to the head) share certain pre-existing cognitive characteristics (e.g., impulsivity, attentional difficulties) that not only make them more accident-prone but may also be the origin of post-mTBI difficulties. Thus, the aim of the second paper was to determine whether the poorer ToM skills detected in preschool children with mTBI are the result of a general-injury effect or a brain-injury-specific effect. A second goal of this article was to examine the evolution of ToM skills following mTBI, from 6 months to 18 months post-injury. To do so, we compared children with mTBI to both a community control group and an orthopedic injury (OI) control group. The findings indicate that children who sustain mTBI performed worse on the desires and emotions reasoning task 6 months post-injury compared to both injured and uninjured counterparts, and this discrepancy in performance was maintained 18 months post-mTBI. Lastly, the third goal of this study was to investigate the link between performances on ToM tasks and social abilities, as measures by parental questionnaires. Overall, these two studies demonstrate a persistent brain-injury-specific effect on ToM skills following early mTBI, and poorer ToM skills are associated with reduced social functioning. This thesis provides evidence that early mTBI can interfere with socio-cognitive development, notably in terms of its repercussions on ToM. These findings support the theory according to which the young, immature brain is more vulnerable to brain insult. Importantly, our studies demonstrate that extrapolation from conclusions drawn with older pediatric age groups may be erroneous because the developmental issues faced by preschool children are fundamentally different. Indeed, neurodevelopmental immaturity may be a driving force that dictates the impact of mTBI on socio-cognitive functioning.

This study investigates the nature of Asperger's Syndrome and specifically the social impairments experienced by learners affected by this syndrome. The incorrect social language, narrow interests and repetitive routines, and the deficits of theory of mind, central coherence and executive functioning of learners with Asperger's Syndrome are also outlined, and an attempt is made to relate these impairments to the social difficulties that learners with Asperger's Syndrome may experience in any inclusive setting. Chapters two and three comprise an in-depth literature study on this specific subject, thus forming a basis for the empirical research reported in chapter five. A qualitative research design is used, first to gain information about and understanding of the nature of the social impairments that afflict learners with Asperger's Syndrome, and secondly to gauge the effectiveness of using social stories as a means to assist the social development of affected learners. More specifically, an ethnographic research design has been chosen for its flexibility which readily permits last-minute adjustments to suit any design, and also because it helps to give meaning to personal encounters. The sensitive nature of the topic is another important reason for choosing this approach (ie. interaction with the researcher could be "fine-tuned" to achieve the ends of this adapted interview situation effectively, circumspectly and safely without undue upset for all concerned). The interview responses of two mothers of learners with Asperger's Syndrome, as well as the observation of these learners are reported. The results of the interviews and observations are checked against the literature study for corroboration in order to bring about a more positive awareness of the impairments experienced by these learners. The technique of social stories was investigated as a method of enhancing the social development of learners with Asperger's Syndrome. Three specific social stories were developed for this research in order to test the effectiveness of this method. Positive outcomes were achieved after implementation of the stories. Results of this study indicated that knowledge and understanding of Asperger's Syndrome, as well as positive attitudes, are critical to ensure the acceptance and accommodation of learners with Asperger's Syndrome in the school environment and in society as a whole. Also, the issue of accommodating learners with Asperger's Syndrome in an inclusive setting should receive concerted attention since it can have major implications for their educational prospects. / Educational Studies / Thesis (D. Ed.)

nÃo hà / A Teoria da Mente (ToM), a habilidade de compreender estados mentais, à considerada indispensÃvel no estabelecimento das interaÃÃes sociais para o desenvolvimento da linguagem. Estudos de Wimmer e Perner (1983), Baron-Cohen, Leslie e Frith (1985) e Frith (1995) investigaram a vinculaÃÃo entre ToM, DÃficits Especificamente LinguÃsticos (DEL) e Transtorno do Espectro do Autismo (TEA), buscando encontrar relaÃÃes de interdependÃncia. IndivÃduos diagnosticados com TEA apresentam atrasos no processamento da ToM, o que pode resultar, de acordo com nossa hipÃtese, em dificuldades referentes à compreensÃo de enunciados que expressem estados mentais de emoÃÃo. Para investigar esta relaÃÃo, estudamos crianÃas com TEA leve e comparamos com um grupo controle. Realizamos a Escala de Tarefas de Teoria da Mente (Wellman e Liu, 2004) para avaliar o nÃvel de ToM dos grupos estudados e uma tarefa experimental. A tarefa consistia na identificaÃÃo de uma frase ouvida com a figura correspondente (alvo) em meio a trÃs figuras, uma competitiva e duas distratoras. A movimentaÃÃo ocular dos participantes foi registrada. As frases foram manipuladas para a posiÃÃo do adjetivo que expressa o estado mental, com duas condiÃÃes experimentais: adjetivo na oraÃÃo relativa; adjetivo na oraÃÃo matriz. Os resultados sugerem uma correlaÃÃo entre o nÃvel de ToM e o tempo de reaÃÃo de cada grupo. O grupo com TEA reflete uma movimentaÃÃo ocular de padrÃo diferente do controle, em funÃÃo das mÃtricas registradas. Como à apontado na literatura, existe uma relaÃÃo entre ToM e TEA e entre ToM e DEL, nosso interesse foi o de investigar se no autismo as possÃveis dificuldades de processamento das oraÃÃes relativas teriam alguma semelhanÃa com o processamento em DEL. A busca por evidÃncias de DEL em grupos com TEA leve ou de altas habilidades tem por finalidade precÃpua uma adequada e precisa compreensÃo da patologia com vistas à producÃo de materiais didÃticos inclusivos para esta populaÃÃo. / Theory of Mind (ToM), the ability to understand mental states, is considered indispensable in the establishment of social interactions and for the development of language. Wimmer and Perner (1983), Baron-Cohen, Leslie and Frith (1985) and Frith (1995) investigated the link between ToM, Specific Language Impairments (SLI) and the Autism Spectrum Disorder (ASD), seeking to find relations of interdependence. Individuals diagnosed with ASD have delays in the processing of ToM, which may, according to our hypothesis, result in difficulties regarding the understanding of statements that express mental states of emotion. To investigate this possibility, we studied children with mild ASD and compared their results with a control group. We performed the ToM Scale (Wellman and Liu, 2004) to assess the ToM level of our groups, as well as an experimental task. The task consisted in matching a sentence the participants heard with the corresponding figure (target) among other three figures, in which one competed with the target and the other two were distractors. The ocular movement of all participants was recorded. The sentences were manipulated regarding the position of the adjective that expressed the mental state. Therefore, we had two experimental conditions: adjective in the relative sentence and the adjective in the main sentence. The results suggest a correlation between the ToM level and the reaction time of each group. The ASD group shows a different ocular movement pattern than the control group, according to the metrics recorded. As it is pointed out in the literature, there is a relationship between ToM and ASD, as well as between ToM and SLI. Our interest was to investigate whether in autism the possible difficulties of processing the relative clauses would have some similarity to the processing in SLI. The search for evidence of SLI in patients with mild ASD or highly functional autism has the adequate and precise final objective of understanding the pathology in hopes of producing appropriate educational material for this population.

More than two hundred years ago David Hume together with his fellow philosopher Adam Smith posited, that ethical behaviour arises from so called: "moral sense". In the other words, they share the same idea, that passions are principle evoking and guiding human behaviour. Hume claim: "Reason is, and ought only to be the slave of the passions" (…). It is possible that this statement - among others - woke up from the 'dogmatic dream' one of the greatest philosophers of all time - Immanuel Kant, who propose, - contrary to Hume - that reason but not necessary passions can determinate human actions. In the question of what rule the passions in ethics have, it seems to be helpful to use the knowledge which follows from recent science. During this thesis we will use methods such as: comparison, analysis and synthesis. Main aim of this thesis will be to deal with the following question: what relationship can be observed between empathy, "moral sense" and ethical behaviour in perspective of recent science. This enquiry will therefore try to deal with the old question: what the the relationship between reason, passions and ethical behaviour is.

La mémoire épisodique est la fonction neurocognitive humaine permettant de se souvenir des événements passés situés dans leur contexte spatio-temporel ainsi que de se rappeler d'exécuter des actions futures spécifiques et d'imaginer des événements futurs variés. Comme d'autres capacités complexes, son développement est lié à d'autres fonctions telles que les fonctions exécutives et la théorie de l'esprit. Elle peut être évaluée avec du matériel de laboratoire nécessitant une mémorisation de nouvelles informations et d'actions futures à réaliser plus tard (mémoires rétrospective et prospective, respectivement), ainsi que via des événements personnels (rappel du passé et imagination du futur ou mémoire autobiographique passée et future, respectivement). L'objectif de cette thèse était, d'une part, de comparer les aspects passé et futur de la mémoire épisodique dans une approche développementale de l'enfant d'âge scolaire au jeune adulte, tout en explorant les mécanismes sous-jacents. D'autre part, le but était également de comparer des tâches autobiographiques et des tâches de laboratoire plus écologiques en réalité virtuelle.Les résultats suggèrent un développement plus progressif de l'aspect futur de la mémoire épisodique (plus de différences chez les enfants), tandis que l'aspect passé semble être bien développé à l'adolescence. Concernant les mécanismes, les performances aux tâches autobiographique et en réalité virtuelle (corrélées entre elles) sont liées aux fonctions exécutives et aux capacités narratives ; de plus, les capacités de rappel lors du test de réalité virtuelle dépendent des fonctions exécutives, la mémoire autobiographique passée et future et la théorie de l'esprit (seulement pour le futur), tandis que les capacités de mémoire autobiographique dépendent de la mémoire du futur en réalité virtuelle en plus des fonctions exécutives et de l'âge.Ces données démontrent que malgré un développement plus progressif de l'aspect futur que passé de la mémoire épisodique, le fonctionnement mnésique dans des environnements virtuels est comparable à la mémoire au quotidien, compte tenu de leurs inter-corrélations et de leurs mécanismes au moins en partie communs. Par ailleurs, les tâches de réalité virtuelle peuvent trouver toute leur utilité dans l'évaluation des patients pédiatriques neurologiques dont les déficits mnésiques peuvent être plus ou moins subtils et se refléter plus aux contextes quotidiens qu'aux contextes des évaluations de type papier-crayon. / Episodic memory is the uniquely human neurocognitive function that enables us to recall past events situated in their spatio-temporal context and to remember to carry out specific future actions as well as imagine various personal future events. As all complex abilities, its functioning is linked to other cognitive capacities such as executive functions and theory of mind. It can be assessed with laboratory-based materials requiring the memorization of information and future actions to be recalled later (retrospective and prospective memory, respectively) and via personal events (recalling past ones and imagining future ones or past and future autobiographical memory, respectively). The aim of this thesis was, on the one hand, to compare both past and future aspects of episodic memory functioning in a wide developmental age span (from young schoolchildren to young adults), and to explore underlying developmental mechanisms. On the other hand, we also aimed to compare personal events¿ (autobiographical) tasks with more ecological laboratory tasks using virtual reality. Results suggest a more progressive development of the future aspect of episodic memory (more differences between children), whereas both retrospective and past autobiographical memory seem to be quite functional by adolescence. Regarding mechanisms, both autobiographical and virtual reality performance, in addition to correlating with each other, are linked to executive functions and narrative abilities; also, memory abilities assessed via virtual reality depend on executive functions, past and future autobiographical memory and (only future memory) on theory of mind performance, whereas autobiographical memory abilities depend on virtual reality-based future memory in addition to executive functions and age. Our data demonstrate that despite a more progressive development of the future aspect of episodic memory than of its past aspect, memory functioning in virtual environments is indeed comparable to daily life memory, as these abilities are strongly inter-linked and have at least partly common mechanisms. Also, virtual reality tasks can be used for memory assessments in pediatric neurological patients whose potential memory deficits can be more or less subtle and thus more detectable in daily life contexts as opposed to paper-and-pencil types of contexts.

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