Uppsatsens syfte är att undersöka hur drömmen gestaltas i romanen Alice i Underlandet och Tim Burtons filmadaption från 2010. Tillvägagångssättet för att uppnå syftet är en intermedial analys kombinerat med teorier om drömmar i film samt Freuds teorier om drömmar i litteratur. Uppsatsens frågeställning är hur gränsen mellan dröm och verklighet är gestaltad, som besvaras genom en jämförelse mellan romanen och filmadaptionen. Gestaltningen av drömmen syns tydligast i kontrast till Alice vakna verklighet eftersom det då går att se vad som skiljer drömmen från verkligheten. Genom en enskild analys av romanen och filmen, samt en jämförande analys av båda medierna har uppsatsens slutsats fastställts. Slutsatsen är att filmens gestaltning av gränsen mellan dröm och verklighet består av en markerande passage mellan dröm och verklighet, medan romanen gestaltar gränsen mellan dröm och verklighet som en flytande övergång.  Romanen gestaltar övergången till drömvärlden främst genom text där Alice funderande blir en övergång till drömmandet. Filmen möjliggör även tolkningen att Underlandet finns på riktigt och därmed inte är en dröm.

導熱介面材料(Thermal Interface Materials, TIM)是所有電子相關產品不可或缺的組成元素之一，沒有了它，市面上就不會有電腦、遊戲機、智慧型手機，也不會有電視機、LED燈，更不會有油電混合車；既然如此不可或缺，但它卻又不造就了是電子產業慣例定義中的關鍵零組件。如此特殊的屬性與定位，導熱介面材料的不凡與平凡。 台灣廠商高柏科技過去十年，趁著消費性電子產品的興起，投入導熱介面材料的生產與銷售，並且堅持自行研發產品，十年間已見規模。但是由於小廠迅速冒出，削價競爭，殺戮慘烈，平凡的低階產品市場已成紅海。有鑑於全球總體的大趨勢，節能減碳需求與日俱增，導熱、散熱等熱管理產業已然成為下一波的主流市場，高柏科技是否可再一次順應潮流，再創另一個豐收的十年，全球競爭力的提高將是成敗關鍵。 高柏科技於是亟思運用既有核心競爭優勢，輔以積極開闢海外市場，希望以全球佈局的高度，以敏銳的市場洞察力，察覺導熱介面材料下一個世代的產品應用之星，找到一片屬於導熱介面材料的不凡的深湛藍海。 / Thermal Interface Materials (TIM) is one of key components in many electronics applications. TIM generally works to solve thermal issues in these electronic products. T-Global Technology Co., one of the top 15 leading companies in the global TIM industry, has been building its own brand by manufacturing and marketing it own products since 10 years ago. The company faces much higher competitions from producers of emerging markets who focus on the low-cost or entry-lever productions. This study considers and investigates how to develop sustainable growth strategies in the current situation. A thorough analysis suggests that strategies of deeper penetrating and expanding into global markets by leveraging the company's core competence may well serve the purpose.

Film adaptations are becoming more popular and past critics and scholars have discussed films based on dramas and novels. However, few have explored the children’s literature genre. In discussing such a topic, it takes more than just debating whether the novel or book is better. A discussion on what elements have been maintained, removed, or added in such an adaptation has to be made along with its success or failure. With this in mind, Roald Dahl’s 1964 novel, Charlie and the Chocolate Factory, and its two film adaptations will be explored along with an analysis of film adaptation theory to show that the first version of the novel succeeds and the second one fails.

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Film adaptations are becoming more popular and past critics and scholars have discussed films based on dramas and novels. However, few have explored the children’s literature genre. In discussing such a topic, it takes more than just debating whether the novel or book is better. A discussion on what elements have been maintained, removed, or added in such an adaptation has to be made along with its success or failure. With this in mind, Roald Dahl’s 1964 novel, Charlie and the Chocolate Factory, and its two film adaptations will be explored along with an analysis of film adaptation theory to show that the first version of the novel succeeds and the second one fails.

A importância do investimento em capital humano para o crescimento econômico de um país foi o que motivou esta dissertação. Procuramos explicá-lo analisando a eficácia na utilização da verba do Programa Nacional de Assistência Estudantil (PNAES), através do desempenho acadêmico dos estudantes. Inicialmente, apresentamos uma revisão de alguns modelos desenvolvidos para explicar o crescimento econômico e após, incluímos a visão dos economistas Adam Smith e Alfred Marshall sobre a relação entre crescimento econômico e educação. A Teoria do Capital Humano nas visões de Theodore Schultz, Gary Becker e Jacob Mincer foi apresentada e comentamos a influência do nível de educação no crescimento econômico e as externalidades positivas da educação. Através de uma perspectiva histórica, mostramos como a educação superior foi expandindo ao longo dos anos e, através de pesquisa documental, apresentamos as mais recentes políticas públicas educacionais para o ensino superior no Brasil. Abordamos amplamente o PNAES e sua aplicação na Universidade Federal do Rio Grande do Sul (UFRGS). Foi realizada a análise dos dados da pesquisa, através do teste t-Student para duas amostras independentes, com o propósito de verificar se as ações motivadas pelo PNAES têm garantido igualdade de condições entre os estudantes em vulnerabilidade socioeconômica e que são beneficiários do PNAES e os demais estudantes. Optamos por utilizar a Taxa de Integralização Média (TIM) do curso e a do estudante para avaliar o desempenho acadêmico. Concluímos que o PNAES foi parcialmente eficaz quando comparamos o desempenho acadêmico dos estudantes de graduação da UFRGS: beneficiados e não beneficiados, cujas médias das TIMs percentuais não são iguais, mas os dois grupos apresentaram uma média da TIM percentual superior a 50% da média da TIM dos respectivos cursos, evidenciando que os estudantes vão conseguir concluir o seu curso no tempo máximo permitido pela Universidade. No grupo de estudantes que ingressaram na modalidade baixa renda, os dados evidenciaram que o PNAES está sendo eficaz porque não existe igualdade entre as médias das taxas percentuais e, também, observamos que os estudantes que solicitaram os benefícios apresentam, na média, taxas maiores do que os demais. Recomendamos a realização de estudos detalhados do desempenho acadêmico por curso, o acompanhamento pedagógico aos estudantes beneficiados, a manutenção de banco de dados atualizado e a avaliação permanente do PNAES por meio de indicadores de monitoramento. / The importance of investment in human capital for the economic growth of a country was the motivation for this thesis. We attempt to explain this by analyzing the efficacy in the use of the National Program of Student Assistance (PNAES) through the analysis of the academic performance of students. We begin by showing a review of some models developed to explain the economic growth. Then, we introduce the views of the economists Adam Smith and Alfred Marshall on the relation between economic growth and education. We then present the Human Capital Theory from the viewpoints of Theodore Schultz, Gary Becker and Jacob Mincer and comment on the influence of the level of education on the economic growth and the positive externalities of education. Next, we use a historical perspective to demonstrate how higher education has expanded over the years, and we use documentary research to present the most recent affirmative actions in higher education in Brazil. We approach in detail the application of PNAES at Universidade Federal do Rio Grande do Sul (UFRGS). We used Student's t-test for the data analysis of two independent samples in order to verify if the actions encouraged by PNAES have been assuring equal conditions among regular students and students who face social economic vulnerability and are beneficiaries of PNAES. We use the course and the student's Average Completion Rates (TIM) to evaluate academic performance. Based on the comparison between students of higher education at UFRGS who are beneficiaries of PNAES and students who are not beneficiaries of PNAES, we concluded that PNAES was partially effective. The percentage TIMs are not the same for the two groups, but both have percentage TIM above 50% in regards to the average TIM of the respective courses. This shows both groups of students will be able to conclude their courses within the time allowed by the university. Considering only the group of students who joined the university through the low-income modality, data show that PNAES has been effective because there is no equality between the average percentage rates. We have also noted that students who applied for the grant have, on average, higher rates than the remaining students do. We recommend the conduction of detailed studies on academic performance per course, pedagogic supervision of beneficiaries, maintenance of updated database, and permanent evaluation of PNAES with monitoring indicators.

The purpose of this diploma thesis is an analysis of selected texts of three popular American authors (Stephenie Mayer, Anne Rice, Tim Burton), who develop the tradition of Gothic literature in their prose writing and film making. This thesis attempts to show how the particular Gothic elements are used in selected works (ex.: the vampire or monster character, the theme of violence or death). In the introductory theoretical chapter the specific character of Anglo-American Gothic prose is explained, and in the following chapters the separate themes are analysed. In this context the literary influences, as well as the originality of the stories, are considered (Horace Walpole, Mary Shelley, Ch. R. Maturin, Bram Stoker), and the contribution of the analysed texts for the coming development of Gothic literature is assessed.

A importância do investimento em capital humano para o crescimento econômico de um país foi o que motivou esta dissertação. Procuramos explicá-lo analisando a eficácia na utilização da verba do Programa Nacional de Assistência Estudantil (PNAES), através do desempenho acadêmico dos estudantes. Inicialmente, apresentamos uma revisão de alguns modelos desenvolvidos para explicar o crescimento econômico e após, incluímos a visão dos economistas Adam Smith e Alfred Marshall sobre a relação entre crescimento econômico e educação. A Teoria do Capital Humano nas visões de Theodore Schultz, Gary Becker e Jacob Mincer foi apresentada e comentamos a influência do nível de educação no crescimento econômico e as externalidades positivas da educação. Através de uma perspectiva histórica, mostramos como a educação superior foi expandindo ao longo dos anos e, através de pesquisa documental, apresentamos as mais recentes políticas públicas educacionais para o ensino superior no Brasil. Abordamos amplamente o PNAES e sua aplicação na Universidade Federal do Rio Grande do Sul (UFRGS). Foi realizada a análise dos dados da pesquisa, através do teste t-Student para duas amostras independentes, com o propósito de verificar se as ações motivadas pelo PNAES têm garantido igualdade de condições entre os estudantes em vulnerabilidade socioeconômica e que são beneficiários do PNAES e os demais estudantes. Optamos por utilizar a Taxa de Integralização Média (TIM) do curso e a do estudante para avaliar o desempenho acadêmico. Concluímos que o PNAES foi parcialmente eficaz quando comparamos o desempenho acadêmico dos estudantes de graduação da UFRGS: beneficiados e não beneficiados, cujas médias das TIMs percentuais não são iguais, mas os dois grupos apresentaram uma média da TIM percentual superior a 50% da média da TIM dos respectivos cursos, evidenciando que os estudantes vão conseguir concluir o seu curso no tempo máximo permitido pela Universidade. No grupo de estudantes que ingressaram na modalidade baixa renda, os dados evidenciaram que o PNAES está sendo eficaz porque não existe igualdade entre as médias das taxas percentuais e, também, observamos que os estudantes que solicitaram os benefícios apresentam, na média, taxas maiores do que os demais. Recomendamos a realização de estudos detalhados do desempenho acadêmico por curso, o acompanhamento pedagógico aos estudantes beneficiados, a manutenção de banco de dados atualizado e a avaliação permanente do PNAES por meio de indicadores de monitoramento. / The importance of investment in human capital for the economic growth of a country was the motivation for this thesis. We attempt to explain this by analyzing the efficacy in the use of the National Program of Student Assistance (PNAES) through the analysis of the academic performance of students. We begin by showing a review of some models developed to explain the economic growth. Then, we introduce the views of the economists Adam Smith and Alfred Marshall on the relation between economic growth and education. We then present the Human Capital Theory from the viewpoints of Theodore Schultz, Gary Becker and Jacob Mincer and comment on the influence of the level of education on the economic growth and the positive externalities of education. Next, we use a historical perspective to demonstrate how higher education has expanded over the years, and we use documentary research to present the most recent affirmative actions in higher education in Brazil. We approach in detail the application of PNAES at Universidade Federal do Rio Grande do Sul (UFRGS). We used Student's t-test for the data analysis of two independent samples in order to verify if the actions encouraged by PNAES have been assuring equal conditions among regular students and students who face social economic vulnerability and are beneficiaries of PNAES. We use the course and the student's Average Completion Rates (TIM) to evaluate academic performance. Based on the comparison between students of higher education at UFRGS who are beneficiaries of PNAES and students who are not beneficiaries of PNAES, we concluded that PNAES was partially effective. The percentage TIMs are not the same for the two groups, but both have percentage TIM above 50% in regards to the average TIM of the respective courses. This shows both groups of students will be able to conclude their courses within the time allowed by the university. Considering only the group of students who joined the university through the low-income modality, data show that PNAES has been effective because there is no equality between the average percentage rates. We have also noted that students who applied for the grant have, on average, higher rates than the remaining students do. We recommend the conduction of detailed studies on academic performance per course, pedagogic supervision of beneficiaries, maintenance of updated database, and permanent evaluation of PNAES with monitoring indicators.

No description available.

Hepatitis C virus (HCV) induces a high rate of chronic infection via dysregulation of host immunity. We have previously shown that T-cell immunoglobulin and mucin domain protein-3 (Tim-3) is up-regulated on monocyte/macrophages (M/Mφ) during chronic HCV infection; little is known, however, about the transcription factor that controls its expression in these cells. In this study, we investigated the role of transcription factor, T-box expressed in T cells (T-bet), in Tim-3 expression in M/Mφ in the setting of HCV infection. We demonstrate that T-bet is constitutively expressed in resting CD14+ M/Mφ in the peripheral blood. M/Mφ from chronically HCV-infected individuals exhibit a significant increase in T-bet expression that positively correlates with an increased level of Tim-3 expression. Up-regulation of T-bet is also observed in CD14+ M/Mφ incubated with HCV+ Huh7.5 cells, as well as in primary M/Mφ or monocytic THP-1 cells exposed to HCV core protein in vitro, which is reversible by blocking HCV core/gC1qR interactions. Moreover, the HCV core-induced up-regulation of T-bet and Tim-3 expression in M/Mφ can be abrogated by incubating the cells with SP600125 – an inhibitor for the c-Jun N-terminal kinase (JNK) signalling pathway. Importantly, silencing T-bet gene expression decreases Tim-3 expression and enhances interleukin-12 secretion as well as signal transducer and activator of transcription 1 phosphorylation. These data suggest that T-bet, induced by the HCV core/gC1qR interaction, enhances Tim-3 expression via the JNK pathway, leading to dampened M/Mφ function during HCV infection. These findings reveal a novel mechanism for Tim-3 regulation via T-bet during HCV infection, providing new targets to combat this global epidemic viral disease.