No Brasil a geração de energia elétrica é predominantemente baseada no uso de fontes renováveis e obtida por meio de centrais hidroelétricas. Ainda assim é necessária a diversificação das fontes de suprimento de energia para a geração de eletricidade quando o recurso hídrico for escasso. Uma alternativa é utilizar gás natural como combustível para as usinas termoelétricas, como vem sendo introduzido na matriz energética de outros países, permitindo a diversificação das fontes energéticas dos mesmos. A indústria do gás natural, assim como outras atividades industriais, não está isenta de acidentes que podem provocar graves consequências à integridade das pessoas e das propriedades. Por este motivo, é necessário desenvolver estudos para determinar quais são as possíveis causas que poderiam ocasionar estes acidentes, e quais são os possíveis cenários associados a estas falhas especificamente na área do transporte de GNL (Gás Natural Liquefeito). É neste contexto que este trabalho de pesquisa tem por objetivo desenvolver um método, baseado nas técnicas de análise de risco, que permita identificar os principais cenários de falha associados à ocorrência de um vazamento de GNL ou de boil-off durante as operações de carga e/ou descarga de navios. Neste cenário, considera-se a presença das barreiras de proteção destinadas a conter esse evento iniciador de perigo no sistema de carga e descarga do navio transportador de GNL, quando o navio está atracado no porto. Adicionalmente à apresentação do método, e como resultado do trabalho, são identificados quais os componentes que pertencem ao circuito de carga e descarga de GNL, e que tenham uma categoria de risco denominada como Crítica (C), Moderada (M) ou Não Crítica (NC). Finalmente, a implantação do método propõe medidas que ajudam a diminuir o nível de risco associado aos componentes denominados críticos, a fim de garantir uma operação segura e livre de acidentes que ponham em risco a integridade dos operadores, dos equipamentos e do ambiente. / Although the electricity generation in Brazil is predominantly based on renewable sources and obtained by means of hydroelectric power plants, it is still necessary to diversify sources of energy supply to generate electricity when the water resource is scarce. An alternative is the use natural gas as fuel for power plants, once it has been introduced in the energy matrix of other countries, allowing the diversification of their energy sources. The natural gas industry, as well as other industrial activities, is not free from accidents, which can cause serious consequences to the integrity of people and properties. For this reason, it is necessary to develop studies to determine what are the possible causes that could lead to serious accidents and what are the possible scenarios of these faults specifically in the area of LNG (Liquefied Natural Gas) transportation. In this context, this research aims to develop a method based on risk analysis concepts which identifies the main failure scenarios given the occurrence of LNG or boil-off leakage during ship loading and unloading operations, considering the presence of containment barriers designed to hold this hazard initiator event in loading and unloading system of the LNG carrier when the ship is in harbor. In addition to the method presentation this research identifies which are the components of LNG loading and unloading circuit, which have a risk category classified as Critical (C), Moderate (M) and NonCritical (NC). Finally, the method implementation allows the proposal of safety and maintenance measures to help reducing the risk level in order to ensure safe operation, free of accidents that endanger the integrity of the operators, the equipment and the environment.

La réparation osseuse est assurée par le recrutement constant de cellules souches/progéniteurs ostéo-compétents de nature hématopoïétique (CSH/PH), et mésenchymateuse (CSM). Une approche prometteuse pour le traitement des défauts osseux graves consisterait à favoriser le recrutement et la mobilisation des CSH/PH et des CSM à partir de la moelle osseuse vers le site de lésion. Plusieurs facteurs environnementaux sont connus pour moduler la prolifération, la mobilisation et la différenciation des progéniteurs ostéocompétents, dont l’hypoxie et l’hypodynamie (absence de contraintes mécaniques). Le but de ce travail de thèse a été d’investiguer in vivo l’impact de l’hypoxie respiratoire et de l’absence de contraintes mécaniques, appliquées séparément ou ensemble sur i) la mobilisation des progéniteurs ostéocompétents et sur ii) la réparation d’un défaut osseux cavitaire fémoral chez la souris. Sur un modèle murin dépourvu de défaut osseux, nos données montrent que l’hypoxie respiratoire est un agent mobilisateur des progéniteurs ostéocompétents, et qu’elle pourrait donc potentiellement exercer des effets bénéfiques sur la réparation osseuse. Toutefois, les effets de l’hypoxie sont modulés selon le statut hypodynamique ou non de l’animal. L’absence de contraintes mécaniques limite la mobilisation des progéniteurs érythrocytaires et mésenchymateux initiée par l’hypoxie, suggérant un effet potentiellement délétère de l’hypodynamie en condition hypoxique dans le contexte de la réparation osseuse. Chez les souris opérées, nous confirmons que l’hypoxie respiratoire déclenchée lors des phases de remodelage améliore la réparation du défaut osseux cavitaire. Une mobilisation des progéniteurs mésenchymateux et hématopoïétiques du fémur contra-latéral vers le fémur opéré est noté, mais le mode d’action de l’hypoxie passerait plutôt par une accélération du mécanisme de réparation dans la zone lésée. De façon intéressante, nous montrons que l’hypodynamie ne diminue pas le bénéfice apporté par l’hypoxie respiratoire à la réparation osseuse. En conclusion, ce travail de thèse identifie l’hypoxie respiratoire comme un candidat thérapeutique pertinent pour l’amélioration de la réparation osseuse. Bien que la perte des contraintes mécaniques module la biologie des cellules ostéoprogénitrices en absence de lésion, l’hypodynamie ne semble pas influencer la consolidation osseuse dans le cadre d’une amélioration de la réparation par un épisode hypoxique tardif. / Many environmental factors are known to influence bone cell fate, including proliferation, mobilization and differentiation of osteoprogenitor cells deriving from both hematopoietic and mesenchymal lineages. Among these factors, hypoxia and unloading (lack of mechanical loading / hypodynamia) are of particular interest. This study aims at investigating the impact of short-term hypobaric hypoxia and hindlimb unloading applied alone or in combination i) on the mobilization of osteocompetent progenitor cells on mice and ii) on the healing in a mouse model of surgical metaphyseal bone defect.In mice free of bone defect, our data indicate that respiratory hypobaric hypoxia acts as a mobilizing stimulus for osteoprogenitor cells. However, the effects of hypoxia in the bone marrow depend on whether mice are subjected to hindlimb unloading or not: hypodynamia tends to restrain the mobilization of both mesenchymal and erythroid progenitors under hypoxia. This suggests a potential detrimental influence of hypodynamia in the course of bone healing in hypoxic condition.In mice with surgery, we showed that hypobaric hypoxia during the remodelling process strongly enhances bone healing. A mobilization of both mesenchymal and hematopoietic progenitors is detected from the contralateral femur to the operated femur. In the lesion area, an acceleration of the repair process is evidenced. Interestingly, hindlimb unloading does not exert any negative influence on bone repair in our animal model. In conclusion, this study identifies delayed hypobaric hypoxia as a potent candidate to enhance bone healing. Even if unloading exerts significant effects on the biology of osteoprogenitor cells on mice free of bone defect, its influence is not detrimental for bone repair.

Die Nanoindentation ist ein inzwischen etabliertes Verfahren zur Bestimmung der Materialkennwerte Härte und Elastizitätsmodul in kleinen Größendimensionen. Eine zusätzliche Bestimmung der Fließspannung aus solchen Nanoindentationsexperimenten würde deren Einsatzmöglichkeiten deutlich erweitern und zum Beispiel für die Bauteilauslegung kleiner Strukturen, Schichtcharakterisierung und die Beschaffung von Simulationseingangsdaten einen großen Fortschritt bedeuten. Diese Gründe machen das Thema zu einem aktuellen Forschungsgegenstand. In der vorliegenden Arbeit steht deswegen die Bewertung von Fließspannungsbestimmungsverfahren für Massivmaterialien in der Nanoindentation mittels einer Kombination aus Finite-Elemente-Simulationen und umfangreichen Experimentaldaten im Zentrum. Im Speziellen wird dabei das Konzept des effektiv geformten Indenters mit dem erweiterten Hertzschen Ansatz und dessen Anwendung zur Fließspannungsbestimmung aus Eindringversuchen mit selbstähnlichen Berkovichpyramiden betrachtet. Zur Bearbeitung dieser Aufgabenstellung wurden unter anderem drei Referenzverfahren zur Fließspannungsbestimmung (die Expanding cavity-Modelle, das Loading partial unloading-Verfahren und Minidruckversuche) ausführlich charakterisiert. Damit konnten dann im Weiteren belastbare Referenzfließspannungen für die umfangreiche Experimentaldatenbasis zur Verfügung gestellt werden. Außerdem wurden die untersuchten Materialien auf den Einfluss der Größenabhängigkeit der Fließspannungen, den Indentation size effect, hin untersucht. Dabei wurden die vorliegenden physikalischen Vorgänge in den Proben beschrieben, dahingehende Unterschiede bei den betrachteten Referenzverfahren charakterisiert und den Fließspannungswerten die Fließzonendimensionen zugeordnet. Mit den damit zur Verfügung stehenden Informationen konnte das Konzept des effektiv geformten Indenters in seiner Anwendung zur Fließspannungsbestimmung grundlegend bewertet werden. Alle Untersuchungen wurden dabei stets parallel mit Hilfe von Simulations- und Experimentaldaten durchgeführt, um tiefere Einblicke in die zu Grunde liegende Mechanik der Fließprozesse zu gewinnen.

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Placement and compaction of the backfill behind an earth retaining wall may induce a vertical shear force at the soil-to-wall interface. This vertical shear force, or downdrag, is beneficial for the stability of the structure. A significant reduction in construction costs may result if the downdrag is accounted for during design. This potential reduction in costs is particularly interesting in the case of U.S. Army Corps of Engineers lock walls. A simplified procedure is available in the literature for estimating the downdrag force developed at the wall-backfill interface during backfilling of a retaining wall. However, finite element analyses of typical U.S. Army Corps of Engineers lock walls have shown that the magnitude of the downdrag force may decrease during operation of the lock with a rise in the water table in the backfill. They have also shown that pre- and post-construction stress paths followed by interface elements often involve simultaneous changes in shear and normal stresses and unloading-reloading. The hyperbolic formulation for interfaces (Clough and Duncan 1971) is accurate for modeling the interface response in the primary loading stage under constant normal stress. However, it has not been extended to model simultaneous changes in shear and normal stresses or unloading-reloading of the interface. The purpose of this research was to develop an interface model capable of giving accurate predictions of the interface response under field loading conditions, and to implement this model in a finite element program. In order to develop the necessary experimental data, a series of tests were performed on interfaces between concrete and two different types of sand. The tests included initial loading, staged shear, unloading-reloading, and shearing along complex stress paths. An extended hyperbolic model for interfaces was developed based on the results of the tests. The model is based on Clough and Duncan (1971) hyperbolic formulation, which has been extended to model the interface response to a variety of stress paths. Comparisons between model calculations and tests results showed that the model provides accurate estimates of the response of interfaces along complex stress paths. The extended hyperbolic model was implemented in the finite element program SOILSTRUCT-ALPHA, used by the U.S. Army Corps of Engineers for analyses of lock walls. A pilot-scale test was performed in the Instrumented Retaining Wall (IRW) at Virginia Tech that simulated construction and operation of a lock wall. SOILSTRUCT-ALPHA analyses of the IRW provided accurate estimates of the downdrag magnitude throughout inundation of the backfill. It is concluded that the extended hyperbolic model as implemented in SOILSTRUCT-ALPHA is adequate for routine analyses of lock walls. / Ph. D.

Trade liberalization and resultantly globalization has led to the relative free flow of goods, services, capital and people. The transport system in South Africa must be highly reliable and rapid to contribute to economic development. The focus of this research study is on the Port/Rail Interface in the Port of Durban which critically assesses the transfer of goods particularly from rail transport to and from vessels within the port precinct. Some of the major constraints identified in the study related to poor infrastructure, operations and levels of services; lack of maintenance, availability of rolling stock, locomotives and cargo stacking space. Transnet's role is pivotal in providing efficient port and rail operations and is currently upgrading infrastructure, operations and capacity of the port and rail services. One of the main objectives of the study is to present recommendations to Transnet management that arise out of the shortcomings identified during the course of the research study. / Transport Economics / M. Comm.

Trade liberalization and resultantly globalization has led to the relative free flow of goods, services, capital and people. The transport system in South Africa must be highly reliable and rapid to contribute to economic development. The focus of this research study is on the Port/Rail Interface in the Port of Durban which critically assesses the transfer of goods particularly from rail transport to and from vessels within the port precinct. Some of the major constraints identified in the study related to poor infrastructure, operations and levels of services; lack of maintenance, availability of rolling stock, locomotives and cargo stacking space. Transnet's role is pivotal in providing efficient port and rail operations and is currently upgrading infrastructure, operations and capacity of the port and rail services. One of the main objectives of the study is to present recommendations to Transnet management that arise out of the shortcomings identified during the course of the research study. / Transport Economics / M. Comm.

External post-tensioning is an attractive technique for strengthening reinforced concrete structures because of its ability to actively control stresses and deflections, speed of installation, minimum interruption for the existing structure, and ease of inspection under service conditions. However, external prestressing implies exposing the tendons to the environment outside the concrete section, which may lead to corrosion in steel tendons. Therefore, the interest in using fiber reinforced polymer (FRP) tendons, which are corrosion resistant, has increased. The present work investigated, experimentally and analytically, the flexural performance of reinforced concrete beams strengthened with externally post-tensioned Carbon FRP (CFRP) tendons, under monotonic and fatigue loadings. Initially, tensile fatigue tests were carried out on CFRP tendon-anchor assemblies to assess their response under repeated cyclic loads, before implementing them in the beam tests. New wedge-type anchors (Waterloo anchors) were used in gripping the CFRP specimens. The assemblies exhibited excellent fatigue performance with no premature failure occurring at the anchorage zone. The fatigue tests suggested a fatigue limit of a stress range of 10% of the tendon ultimate capacity (approximately 216 MPa). Monotonic and fatigue experiments on twenty-eight beams (152x254x3500 mm) were then undertaken. Test parameters included the tendon profile (straight and double draped), the initial loading condition of the beam prior to post-tensioning (in-service and overloading), the partial prestressing ratio (0.36 and 0.46), and the load ranges applied to the beam during the fatigue life (39% to 76% of the yield load). The CFRP tendons were post-tensioned at 40% of their ultimate capacity. The monotonic tests of the post-tensioned beams suggested that overloading the beam prior to post-tensioning increased the beam deflections and the strains developed in the steel reinforcing bars at any stage of loading. However, overloading had no significant effect on the yield load of the strengthened beam and the mode of failure at ultimate. It also had no discernable effect on the increase in the tendon stress at yielding. The maximum increase in the CFRP stress at yield load was approximately 20% of the initial post-tensioning stress, for the in-service and overloaded beams. A very good performance of the strengthened beams was observed under fatigue loading. The fatigue life of the beams was mainly governed by the fatigue fracture of the internal steel reinforcing bars at a flexural crack location. Fracture of the bars occurred at the root of a rib where high stress concentration was likely to occur. No evidence of wear or stress concentration were observed at the deviated points of the CFRP tendons due to fatigue. The enhancement in the fatigue life of the strengthened beams was noticeable at all load ranges applied. Post-tensioning considerably decreased the stresses in the steel reinforcing bars and, consequently, increased the fatigue life of the beams. The increase in the fatigue life was slightly affected by the loading history of the beams. At the same load range applied to the beam, increasing the amount of the steel reinforcing bars for the same post-tensioning level decreased the stress range in the bars and significantly increased the fatigue life of the strengthened beams. In the analytical study, a monotonic model that predicts the non-linear flexural response of the CFRP post-tensioned beams was developed and implemented into a computer program. The model takes into account the loading history of the strengthened beams prior to post-tensioning (in-service and overloading). Good agreement was obtained between the measured and the predicted monotonic results. A strain-life based fatigue model was proposed to predict the fatigue life of the CFRP post-tensioned beams. The model takes into consideration the stress-strain history at the stress raisers in the steel bars. It accounts for the inelastic deformation occurring at the ribs during cycling and the resulting changes in the local mean stresses induced. Good agreement between the experimental and predicted fatigue results was observed. A step-by-step fatigue design approach is proposed for the CFRP externally post-tensioned beams. General conclusions of the study and recommendations of future work are given.

La terre compactée est considérée comme un mélange granulaire dans lequel l'argile joue un rôle de liant mais cette dernière exhibe une forte interaction avec l'eau. Pendant la durée de vie en service, la terre compactée est soumise aux changements de l’humidité relative. En raison de ces changements des conditions ambiantes perpétuels, la teneur en eau dans la terre varie, impactant leur performance mécanique. Le présent travail a ainsi pour but d’étudier l’impact de l’humidité relative et de la teneur d'argile sur le comportement mécanique de la terre compactée. Il se réalisera au travers d’études expérimentales et d'une modélisation constitutive. Dans la première partie de cette thèse, quatre terres régionales de provenances et de teneurs d'argile différentes sont identifiées. Une étude comparative a été réalisée entre le double compactage statique et le compactage dynamique. En parallèle, trois types d'essais spécifiques : essais de succion par la méthode de papier-filtre, essais de retrait et essais d'absorption d'eau, ont été menés pour donner des indications préliminaires quant aux effets d'interaction entre l'eau et l'argile. Dans la deuxième partie, l’impact de l’humidité relative et de la teneur d'argile sur le comportement de cisaillement a été étudié, prenant en compte des cycles de chargement-déchargement. En adoptant une définition particulière de la contrainte effective de Bishop, il a également été observé que les états de rupture dans le plan (p'-q) pour tous les échantillons sont alignés approximativement à une ligne droite unique passant par l'origine, quelque soit la succion et la pression de confinement. Sur la base des résultats expérimentaux, un nouveau modèle constitutif a été développé pour la simulation du comportement mécanique de la terre compactée. Ce nouveau modèle a ainsi été formulé dans la cadre de la mécanique de l'endommagement des milieux continus et de la théorie de Bounding Surface Plasticity. / Compacted earth is regarded as a granular mixture in which clay plays a role of binder but it also exhibits an important interaction with water. During their service life, compacted earth can be subject to large changes in relative humidity. Those perpetual changes of environmental conditions induce continuous changes of water content of the earth that impact significantly its mechanical performances. The present work aimes at studying the mechanical behavior of compacted earth with respect to relative humidity and clay content. It involves an extensive experimental study and a constitutive modelling. In the first part of this thesis, four kinds of local earth are identified with different clay contents. A comparison of compaction method was then conducted between a double static compaction and dynamic compaction. Three types of specific tests: suction test by filter paper method, shrinkage test and sorption-desorption test were carried out, thereby providing a preliminary insight on the interaction effects between clay and water. In the second part, the impact of clay and moisture contents on the shear behavior of compacted earth was investigated taking into account loading-unloading cycles. Adopting a particular definition of Bishop's effective stress, failure states of all samples were observed to lie approximately on a unique failure line crossing the origin in the (p'-q) plane regardless of matric suction and confining pressure. Finally, based on the above experimental results, a new constitutive model was proposed, based on the theories of Bounding Surface Plasticity and continuum damage mechanics, aiming to simulate mechanical behaviour of compacted earth.

Rate-dependent effects introduced during rapid and/or dynamic events have typically been oversimplified to compensate for deficiencies in present analyses. As load test results are generally considered as the basis of performance from which foundations can be designed, it is imperative that the analyzed load test data be as accurate as possible. In an attempt to progress the state of load test data regression, this dissertation addresses two common assumptions made during the regression process: (1) the statnamic damping coefficient is constant throughout the entire load test and (2) the concrete stress-strain relationship is linear-elastic. Also presented is a case study where the inherent features of a rapid load test proved useful in identifying the occurrence and proximity of a structural failure within a drilled shaft.