Multifunctional building is designed as a 4 storey building with one floor underground and three above-ground floors. The building is situated in the administrative area Vajnory Bratislava. Basement includes cellars and 15 parking spaces. The first floor covers commercial premises suitable for civic amenities. In second and third floor are located apartments. Recent third floor is intentionally reduced to achieve a lower index for compliance with a built-up area.

Bakgrund: Bäckenbottenskador är vanligt förekommande vid vaginala förlossningar och kan orsaka många besvärande symtom. Den fysiska påfrestningen påverkar även kvinnors välmående och kan leda till psykisk ohälsa. Syfte: Syftet var att beskriva psykologiska konsekvenser av bäckenbottenskador i samband med förlossning för kvinnor. Metod: Syftet besvarades genom att göra en allmän litteraturstudie baserad på nio kvalitativa artiklar. Artiklarna kvalitetsgranskades och analyserades, därefter skapades en övergripande huvudkategori och tre underkategorier. Resultat: Huvudkategorin var Förlossningsskador medför psykiskt lidande, och dess underkategorier Känsla av skuld och skam, Förlust av kvinnlighet och sexualitet och Besvikelse över vårdens bristande information och stöd. I resultatet framkom att psykologiska konsekvenser såsom oro, skam, ångest, hopplöshet, depression och posttraumatiskt stressyndrom, är en följd av bäckenbottenskador och dess somatiska besvär. Vidare framkom att kvinnor inte fick den vård de var i behov av och upplevde att vården försummade dem och orsakade ytterligare psykisk påfrestning. Konklusion: Litteraturstudien bidrar till en ökad förståelse om hur bäckenbottenskador påverkar kvinnors psykiska välmående. Det behövs utveckling av riktlinjer vad gäller uppföljning och behandling av förlossningsskador. Vidare forskning krävs om hur bäckenbottenskador och sekundärt psykiskt trauma kan förebyggas, repareras, behandlas och rehabiliteras. / Background: Pelvic floor injuries are common due to vaginal delivery and can cause many troublesome symptoms. The physical symptoms affect women’s well-being and can lead to psychological morbidity. Aim: The aim was to describe the psychological consequences of pelvic floor injuries in relation to childbirth for women. Method: The aim was answered by conducting a general literature study based on nine qualitative articles. The articles were quality-tested and analysed, then one overreaching head category were created and three under categories. Results: The head category was Birth injuries causes psychological suffering, and it’s under categories Feeling guilt and shame, Loss of femininity and sexuality and Disappointment with the lack of information and support in healthcare. Women experienced psychological consequences such as shame, anxiety, hopelessness, depression and post-traumatic stress syndrome, secondary to pelvic floor injuries. It was also found that women didn’t receive the care they needed and felt that healthcare professionals neglected them and caused further psychological distress. Conclusion: The general literature study contributes to an increased understanding of how pelvic floor injuries affect women’s mental well-being. There is a need for development of guidelines as to monitoring and treatment of birth injuries. Further research is needed on how pelvic floor injuries and secondary to it psychological trauma can be prevented, repaired, treated and rehabilitated.

The diploma thesis deals with the problem of global pelvic floor dysfunction in patients with cystic fibrosis. The theoretical part is devoted to individual components of dysfunction, thus urinary and fecal incontinence, prolapse and sexual issues. In particular, it focuses on the mechanism of formation and prevalence of individual components and also contains information on the musculoskeletal abnormalities most commonly found in patients with cystic fibrosis. There is also mentioned the impact of incontinence on the quality of life of patients. The experimental part describes a questionnaire survey, hypotheses derived from it and their results with comments. There is also statistical processing of the data and graphical representation of the results. Other important findings from the survey are also listed. The thesis follows the previous bachelor thesis and aims to draw attention to the given issue and break the wall of silence from the ranks of patients and health professionals.

In the light of today’s effort to achieve sustainable future of the planet, timber as building material makes a comeback on the construction market. Since the requirements on the buildings and the internal comfort increase, there is a need for finding new solutions and products; one of them is cross-laminated timber (CLT), which has the potential to be used for high-rise buildings due to its mechanical properties. The aim of this work was to study the vibration performance of CLT floors as it is often the governing factor in design of CLT structures unlike for other common building materials. The orthotropic mechanical properties of CLT were determined by the shear analogy method and verified with a finite element (FE) model of a simply supported beam compared to hand calculations of shear forces, bending moments and deflections. The properties based on Timoshenko’s approach were evaluated as less precise regarding the deflection. The non-composite structural behaviour of a steel-CLT hybrid floor structure was predicted for FE dynamic analysis based on a comparison between modelling exercise and hand calculations. Two different methods, the Concrete Society (SC) and Steel Construction Institution (SCI) methods, both seemed to be applicable for determination of the response factor first since the mechanical properties are not used as input in the calculations. These two methods differ in certain aspects, and based on FE analysis of simply supported slab even the resulting response factor for the CLT differs significantly. Moreover, the hand calculation results were similar to those of the FE analysis for the CS method, but in less agreement for the SCI method. Nevertheless, it is not recommended to reject the latter method based on this study and further studies should be performed on real structures with response factor known from on-site measurements. A part of the first floor of Canary Wharf College was modelled and analysed, and previous measurements of the frequency and response factors enabled a validation of some assumptions. The SCI approach showed to be inadequate for this type of structure and therefore only the CS method was applied further. Analysis of the floor structures supported by walls demonstrated similar results from both the measurements and the dynamic analysis. However, if the floor slab was supported by beams, the response factor was significantly overestimated although on the conservative side. This difference suggests that the modelling of such conditions are not satisfactory. The CS method appears to assess correctly the magnitude of the response factor for CLT floors supported by walls but overestimates it in case of beam supports. The first finding shall be confirmed through analysis of other structures and a more extensive research should focus on the latter one to determine more exact behaviour of the model under different conditions.

La presente investigación alcanza una alternativa de utilizar los muros de suelo reforzado como estribos de puente en la mina Cuajone situado en el departamento de Moquegua, con el objetivo de comprobar si es posible que estas estructuras soporten las altas cargas de los camiones mineros que transitan por los “Haul Road” de la mina. Luego, se desarrolla los procedimientos de diseño estructural del muro MSE con la metodología LRFD según la norma AASHTO. Finalmente, se verifica los resultados que se obtuvieron mediante el modelo y el análisis de los elementos finitos del diseño consolidado en el software PLAXIS y se presentan las conclusiones del caso. En primer lugar, está el capítulo introductorio, que presentar de manera resumida y cualitativa el tema de la tesis y las motivaciones del caso. Se desarrolla el problema planteado y finaliza esta sección con la descripción de los antecedentes históricos de los muros MSE, hipótesis, objetivos y alcances de la presente investigación. Asimismo, se describe de manera extendida los conceptos de los muros MSE, ventajas, desventajas, tipos de sistemas, tipos de refuerzo, tipos de paramentos y sus aplicaciones. Además, se presentan los pasos diseño de los muros como estribo de puente y el procedimiento del análisis sísmico de estos. Finalmente, se describen los conceptos del método de elementos finitos y el análisis del software PLAXIS. En el segundo lugar; se presentan el material y método, considerando el nivel y diseño de investigación, variables y técnicas que se emplearon para poder desarrollar de manera satisfactoria el argumento de la presente tesis. En el tercer lugar, se presentan los resultados de acuerdo a cada objetivo planteado. Al finalizar esta sección, se presentan los desplazamientos de muro MSE como estribo de puente modelado en el software PLAXIS, concluyendo con la afirmación o la negación de la hipótesis. Por último, se presenta las conclusiones, comentarios y recomendaciones de acuerdo al desarrollo y resultados de la presente investigación. / The present investigation achieves an alternative use of the reinforced soil walls as bridge abutments in the Cuajone mine in the department of Moquegua, with the objective that these structures bear the high loads of the mining trucks that transit through the "Haul Road" of the mine. Then, the structural design procedures of the MSE wall are followed with the LRFD methodology according to the AASHTO standard. Finally, the results obtained by means of the model and the analysis of the finite elements of the consolidated design in the PLAXIS software are verified and the conclusions of the case are presented. In the first place, there is the introductory chapter, the summary and qualitative presentation of the topic of the thesis and the motivations of the case. The problem raised and finalized in this section was developed with the description of the historical background of the MSE walls, hypotheses, objectives and scope of the present investigation. In the next chapter, we describe how to extend the concepts of MSE walls, advantages, disadvantages, types of systems, types of reinforcement, types of walls and their applications. In addition, the steps of the walls are presented as bridge abutment and the procedure of the seismic analysis of these. Finally, the concepts of the finite element method and the analysis of the PLAXIS software are described. In the second place; It presents the material and the method, the level and design of the research, the variables and the techniques used to successfully develop the argument of the present thesis. In the third place the results are presented according to each objective. At the end of this section, the displacements of the wall are presented as a work program in the PLAXIS software, concluding with the affirmation or denial of the hypothesis. Finally, the conclusions, comments and recommendations are presented according to the development and results of the present investigation. / Tesis

NMR is gaining increasing interest in civil engineering for applications regarding microstructure characterization as e.g., to determine pore sizes or to monitor moisture transport in porous materials. This study reveals the capability of NMR as a tool for pore size characterization. Therefore, we measured floor screed and synthetic materials at partial and full saturation. For most examined materials, the pore size distribution was successfully determined using either a reference or a calibration method. Since diffusion effects were observed for some samples in single-sided NMR measurements, further tests employing an NMR core analyzer were carried out in a homogeneous magnetic field. The finally obtained surface relaxivity of floor screed (50 μm/s) resulted to be much higher than suggested by literature.

Indoor positioning systems (IPS) has seen an increase in demand because of the needto locate users in environments where Global Navigation Satellite Systems (GNSS) lacksaccuracy. The current way of implementing an IPS is often tedious and time consuming.However, with the improvements of position estimation and object detection on phones,a lightweight and low-cost solution could become the standard for the implementationphase of an IPS. Apple recently included a Light Detection And Ranging (LiDAR) sensorin their phones, greatly improving the phones depth measurements and depth understanding.This allows for a more accurate virtual representation of an environment. This thesisstudies the accuracy of ARKit’s reconstructed world and how different environments impactthe accuracy. The thesis also investigates the use of reference points as a tool to map thereconstructed environment to a geo-referenced map, such as Google Maps and Open StreetMap. The results show that ARKit can create virtual representations with centimetre levelaccuracy for small to medium sized environments. For larger or vertical environments,such as corridors or staircases, ARKit’s SLAM algorithm no longer recognizes previouslyvisited areas, causing both duplicated virtual environments and large drift errors. With theuse of multiple reference points, we showed that ARKit can and should be considered asa viable tool for scanning and mapping small scale environments to geo-referenced floorplans.

Wood construction has increased in the recent years for apartment buildings consisting of four to five floors. Compared to other building materials, wood has great environmental benefits. For a building in a larger scale constructed in wood, cross-laminated timber, also known as CLT is an option. The technology for CLT originated in Sweden during the 1990s and since then the development has increased. CLT has excellent stiffness and strength properties. The design of a floor in CLT is important for how the building and the environment are perceived indoors. The wooden floor is about five times lighter than concrete, which means that measures are required to meet the sound requirements set by Boverkets building regulations in Sweden. This will affect the span. The aim of the project is to present a knowledge overview of CLT and for floor in CLT up to 9 meters in span, to compete with concrete floor in steel and prefabricated concrete frames. The study includes a quantitative methodology using three different data collection methods. These are literature study, document analysis and calculations. The literature study and the document analysis are based on scientific-and research articles, together with manuals. The calculations are carried out in Stora Enso's calculation program Calculatis by Stora Enso. The program follows Eurocode's design principles. The result of the study shows that a CLT-board with laminated beams gives greater span than just a CLT-board does. The calculation means that the plate must meet the deflection requirement L / 300. Research shows that construction with CLT is increasing and there is great potential to obtain a cost-effective reduction of the carbon footprint and at the same time improve the utilization of natural resources by replacing non-renewable building materials such as concrete and steel with CLT. In order to achieve the sound requirements that are established, the CLT floor must be dimensioned thicker and measures such as additional insulation. By looking at the results, the conclusion is drawn that CLT-floor may grow further to compete with concrete floor in the future. Currently the material is considered useful and environmental for smaller constructions for such as smaller houses, due to the sound insulation problem. For larger constructions with the similar problem can timber-concrete composite be an alternative. CLT-floor reinforced with glulam beams may be considered as a choice for larger and bigger constructions because the span widths increase, and the construction can withstand maximum deflection. The study is limited to mainly considering CLT but also a small amount of concrete and glulam. Vibrations and environmental risks such as moisture, sunlight and fire, are not considered. The calculations the work uses are based on Eurocode 5, dimensioning of wooden structures. Other types of design principles have been excluded.

Résumé : Introduction : Parmi les structures anatomiques impliqués dans la statique pelvienne, la continence urinaire et anale, le muscle élévateur de l’anus (MEA), le sphincter urétral (SU) et son innervation ont un rôle déterminant. Au cours de la grossesse, de l’accouchement par voie vaginale, de la chirurgie radicale pelvienne, des lésions des muscles du plancher pelvien ou de son innervation peuvent survenir. Ces lésions sont à l’origine de dysfonctions du plancher pelvien telle que le prolapsus uro-génital ou l’incontinence urinaire. Une meilleure connaissance de l’anatomie musculaire et nerveuse pelvi-périnéale est nécessaire pour diminuer la survenue et traiter ces troubles fonctionnels. Classiquement les muscles du plancher pelvien sont décrits comme entièrement striés sous contrôle somatique (nerf du MEA et/ou nerf pudendal (NP)). La dissection Anatomique Assisté par Ordinateur (DAAO) en utilisant des marqueurs nerveux et musculaires spécifiques peut aujourd’hui compléter les données établies par la dissection conventionnelle classique de sujets anatomiques.Objectif : L’objectif était de décrire l’innervation (origine, topographie, trajet, rapports, fonction) et la structure musculaire du MEA, de décrire l’innervation (origine, topographie, trajet, rapports, fonction) du sphincter urétral pour mettre en perspective les implications potentielles dans les dysfonctions du plancher pelvien.Méthodes : Nous avons étudié 9 fœtus humains (6 féminins et 3 masculins). Des coupes histologiques sériées de 5 µm d’épaisseur ont été effectuées dans les régions pelviennes de 7 fœtus âgés de 18 à 40 semaines de gestation. Pour chaque niveau de coupe, des lames ont été colorées puis traitées en immunohistochimie pour détecter : l’ensemble des fibres nerveuses (anticorps anti-protéine S100), les fibres autonomes cholinergiques (anti-VAChT), les fibres autonomes adrénergiques (anti-TH), les fibres autonomes nitrergiques (anti-nNOS), les fibres somatiques (anti-PMP 22), les fibres sensorielles (anti-CGRP), les fibres musculaires lisses (anti-SMA) et les fibres musculaires striées (anti-MYOG). Les coupes ont ensuite été numérisées par un scanner de haute résolution optique et les images ont été reconstruites en 3D avec le logiciel Winsurf®. Un fœtus additionnel a été entièrement destiné à réaliser de la microscopie électronique afin de confirmer nos résultats au niveau architectural musculaire.Résultats : Nous avons observé une innervation à la fois autonome (plexus hypogastrique inférieur (PHI)) et somatique (nerf du MEA et NP) du MEA. Nous avons individualisé des zones de cellules musculaires lisses au sein du plancher pelvien notamment de la partie médiane sous contrôle autonome (PHI) que nous nommons « compartiment médian musculaire lisse ».Nous avons systématisé le plancher pelvien musculaire en une zone médiale lisse sous contrôle nerveux autonome réalisant une interface entre les viscères pelviens, et une zone musculaire striée latérale sous contrôle nerveux somatique.Enfin, nous avons mis en évidence une double innervation à la fois somatique et autonome du sphincter urétral.Conclusion : La DAAO a permis de mettre en évidence une innervation pelvi-périnéale complexe avec l’intrication du système nerveux somatique et autonome. La fonction du contingent musculaire lisse pelvien reste à préciser. / Abstract : Levator ani muscle (LAM), urethral sphincter (US), and their innervation play a major role in pelvic status, urinary continence and anal continence. During pregnancy, vaginal delivery, pelvic radical surgery, damage of pelvic floor muscles or of their innervation may occur. These lesions are responsible for pelvic floor dysfunction such as urogenital prolapse or urinary incontinence. Better knowledge of pelvi-perineal muscle and nerve anatomy is needed to reduce the occurrence and treat these pelvic floor dysfunctions. Classically pelvic floor muscles are described as entirely striated under somatic control (levator ani nerve (LAN) and /or pudendal nerve (PN)). Computer Assisted Anatomical Dissection (CAAD) using specific nerve and muscle markers can nowadays complete data established by conventional dissection of anatomical subjects.The objective was to describe the innervation and the muscular structure of the levator ani muscle, to describe nerve supply of the urethral sphincter in order to better understand pelvic floor dysfunction.Methods : We studied nine human fetuses (6 female and 3 male). Serial histological sections of 5 μm of thickness were performed in the lumbar and pelvic regions of seven human fetuses aged 18 to 40 weeks of gestation. For each level, slides were stained and then treated in immunohistochemistry to detect: general nerve fibers (anti-protein S100), autonomic cholinergic fibers (anti-VAChT), autonomic adrenergic fibers (anti-tyrosine hydroxylase), autonomic nitrergic fibers (anti-nNOS), somatic nerve fibers (anti-peripheral myelin protein 22), sensory fibers (anti-CGRP), smooth muscle fibers (anti-SMA) and striated muscle fibers (anti-MYOG). The slides were then digitized by a high-resolution optical scanner and the images were reconstructed in 3D using the Winsurf® software. One fetus was entirely reserved for electronic microscopy in order to confirm our results.Results: We observed that LAM innervation is supplied by both autonomic (inferior hypogastric plexus (IHP)) and somatic (LAN and PN). We have individualized areas of smooth muscle cells in the pelvic floor, particularly the median part controlled by the autonomic system that we named “smooth muscle medial compartment”.We systematized within the pelvic floor muscle a smooth medial part under an autonomic nervous control as interface between the pelvic viscera and a lateral striated muscle part under somatic nervous control.Finally, we have demonstrated a dual innervation both somatic and autonomic sphincter urethral.Conclusion : CAAD has demonstrated complex pelvic-perineal innervation with the interaction of the somatic and autonomic nervous system. The function of the pelvic smooth muscle contingent remains to be clarified.

Bakgrund: Förlossningsskador kan leda till fysiska och psykiska besvär. Det finns brister och stora variationer i förlossningsvården i Sverige. Det saknas evidensbaserade riktlinjer för fysioterapi inom området och vilka insatser som har effekt är inte helt klarlagt. Kvinnornas egna upplevelser och erfarenheter spelar stor roll i arbetet för att fylla de kunskapsluckor som finns idag.  Syfte: Syftet med studien var att undersöka fem kvinnors personliga upplevelser och erfarenheter av fysioterapeutiska åtgärder efter att de drabbats av förlossningsskador grad 3–4 och på så sätt öka förståelsen för fysioterapeutiska åtgärder hos fysioterapeuter inom detta område.  Metod: Studien hade en kvalitativ deskriptiv design. Deltagarna var fem kvinnor som drabbats av förlossningsskador av grad 3–4. Rekryteringen skedde via Facebook-gruppen ”Allt om förlossningsskador”. Semistrukturerade intervjuer genomfördes och intervjumaterialet bearbetades genom en kvalitativ innehållsanalys. Resultat: Analysen resulterade i fyra kategorier: Minskad funktion i det vardagliga livet, Brister inom förlossningsvården, Upplevelser av fysioterapeutiska åtgärder och Informanternas förslag till förbättring inom kvinnohälsa samt tio subkategorier.   Konklusion: Studien visade att kvinnorna upplevde att det saknas kunskap och kompetens gällande fysioterapi vid förlossningsskador. Resultatet tyder på att de viktigaste faktorerna i mötet med dessa kvinnor är utförligt information, tydliga instruktioner och bra bemötande av patienten. Behovet av vidare forskning och nya riktlinjer gällande fysioterapi vid förlossningsskador är stort och den fysioterapeutiska grundutbildningen bör inkludera en mer omfattande del om kvinnohälsa. / Background: Women with perineal tears after childbirth often suffer from physical and psychological issues. There are some varieties and deficiencies in the Swedish health care system of maternity care, and there is an absence of evidence-based guidelines in the physiotherapeutic field of maternity care. The women’s perspectives play a major role to fill the gaps of knowledge that exist today.  Purpose: The purpose of this study was to investigate views and experiences of physiotherapy from women with third- and fourth-degree perineal tears to establish a higher knowledge for physiotherapeutic methods.   Method: The study was a semi-structured qualitative interview study that included five women with third- and fourth-degree perineal tears. The participants were recruited through the Facebook group “Allt om förlossningsskador”. Analyzing of the interview material was done through a qualitative content analysis.  Results: The analysis resulted in four categories: Reduced function in everyday life, Deficiencies in maternity care, Experiences of physiotherapeutic measures and The informants’ proposals for improvement in women’s health with ten subcategories.  Conclusion: The study showed that the women felt that there is a lack of knowledge and competence regarding physiotherapy after perineal tears. The results indicate that the most important factors in the meeting with these women are detailed information, clear instructions and good treatment of the patient. Further research and new guidelines regarding physiotherapy for women with perineal tears is needed and the physiotherapeutic education should involve more about women health and rehabilitation of pelvic floor injuries.