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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
501

Os desafios na implementação do macrocampo comunicação e uso de mídias, cultura digital e tecnológica do Programa Mais Educação na rede estadual de educação de Pernambuco

Santana, Simone Santiago de 20 August 2014 (has links)
Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-04-07T12:24:35Z No. of bitstreams: 1 simonesantiagosantana.pdf: 1022143 bytes, checksum: 65c9b92e81b5752553db298a72dcdcd3 (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-04-07T16:35:17Z (GMT) No. of bitstreams: 1 simonesantiagosantana.pdf: 1022143 bytes, checksum: 65c9b92e81b5752553db298a72dcdcd3 (MD5) / Made available in DSpace on 2017-04-07T16:35:17Z (GMT). No. of bitstreams: 1 simonesantiagosantana.pdf: 1022143 bytes, checksum: 65c9b92e81b5752553db298a72dcdcd3 (MD5) Previous issue date: 2014-08-20 / O presente caso de gestão objetivou descrever e analisar os problemas e desafios na implementação do macrocampo Comunicação e Uso de Mídias, Cultura Digital e Tecnológica do Programa Mais Educação (PME) na rede estadual de educação de Pernambuco, a partir do caso da Escola Estadual Y, do município de Paulista, pertencente à GRE Metropolitana Norte, e propor um plano de ação como contribuição para melhoria dessa implementação. A relevância dessa pesquisa que tangencia as questões atinentes à ampliação da jornada escolar ou tempo escolar e, portanto, às políticas de educação integral e em tempo integral é justificada diante do caráter emergente que tem o uso das tecnologias eletrônicas e digitais na escola, considerando que o PME contempla, dentre os macrocampos de conhecimento das escolas urbanas, o de Comunicação e Uso de Mídias, Cultura Digital e Tecnológica. Embora exista uma expressiva produção sobre o PME em termos mais amplos, justifica-se também a escolha dessa temática específica por não existirem publicações a respeito no estado de Pernambuco. Tomou-se como campo de pesquisa a SEE/PE, a GRE Metropolitana Norte e uma escola estadual de jurisdição do município de Paulista - denominada neste estudo de Escola Estadual Y - que fez a adesão ao macrocampo Comunicação e Uso de Mídias, Cultura Digital e Tecnológica do PME em todos os anos, desde a implantação do PME no estado, em 2008. Para a coleta de dados e análise dos elementos interferentes na implementação do macrocampo Comunicação e Uso de Mídias, Cultura Digital e Tecnológica do PME, a metodologia utilizada foi qualitativa, tendo como instrumento de pesquisa entrevistas de roteiros semi-estruturados em duas etapas distintas: uma etapa preliminar com as equipes do PME da SEE/PE e GRE e uma segunda etapa com as mesmas equipes e a equipe pedagógica e de gestão da Escola Estadual Y. Como fundamentação teórica utilizaram-se os estudos de Cavaliere (2007, 2009) sobre a concepção de educação integral, Condé (2012) e Mainardes (2006) a respeito da implementação de políticas públicas e Bonilla (2009) sobre a incorporação das tecnologias no contexto escolar. A partir de análise dos resultados da pesquisa observou-se que problemas de insuficiência e despreparo de recursos humanos e precariedade no monitoramento no âmbito da SEE/PE e da GRE interferiram diretamente na implementação do macrocampo nas escolas. Diante disso, o Plano de Ação Educacional proposto apresenta ações que poderão ser executadas na rede estadual de ensino de Pernambuco com vistas a equacionar as dificuldades na implementação do macrocampo Comunicação e Uso de Mídias, Cultura Digital e Tecnológica do PME, quer seja no âmbito da SEE/PE, das Gerências Regionais de Educação ou das próprias escolas. / The aims of the present case of management were to describe and analyse the problems and challenges in the implementation of macrocampo Communication and Use of Media, Digital and Technological Culture of Mais Educação Program (PME) on the network education of Pernambuco from State School case Y, in Paulista, municipality of Regional Management of Education from North Metropolitan, and to propose an action plan as contribution to improvement of this implementation. The importance of this research that touches the issues concerning the extension of the school journey or school time and therefore the integral education policies and full time is justified faced with the emergency of the use of electronic and digital technologies in school, whereas PME includes, among the macrocampos of knowledge of urban schools, the Communication and Use of Media, Digital and Technological Culture. Although there is a significant production about the PME in broader terms, this specific theme is chosen because there is not this kind of publications in the State of Pernambuco. The State Department of Education of Pernambuco (SEE/PE), The Regional Management of Education/North Metropolitan (GRE) and the State School Y became search field. The State School Y has made membership of the macrocampo Communication and Use of Media, Digital and Technological Culture of PME every year, from the implementation of PME, in the state in 2008. It was used a qualitative methodology to collect information and analyse the facts that involve the implementation of macrocampo Communication and Use of Media, Digital and Technological Culture of Mais Educação Program having as research‟s tools, interviews of semi-structured itineraries in two different stages: a preliminary stage with the same teams of Mais Educação Program of SEE/PE and GRE, and a second stage with the same teams, the educational team and the management team of the State School Y. The studies from Cavaliere (2007, 2009) about the conception of full educational were used as theoretical support, Condé (2012) and Mainardes (2006) about the implementation of public policies and Bonilla (2009) about the incorporation of technologies in the school context. From the analysis results of the research it was pointed out problems of inadequacy and lack of preparation of human resources and insecurity in monitoring under the SEE/PE and GRE interfered directly in the implementation of macrocampo in schools. In the face of this, the proposed Educational Action Plan presents actions that can be executed in the State schools of Pernambuco with a view to addressing the difficulties in implementing the macrocampo Communication and Use of Media, Digital and Technological Culture of the PME, either within the SEE/PE, Regional Managements of Education or the schools themselves.
502

O Programa ‘Mais Educação’ e a educação integral na escola pública: uma análise a partir da perspectiva da formação onilateral

Santos, Magda Gisela Cruz dos 31 March 2014 (has links)
Submitted by Leonardo Lima (leonardoperlim@gmail.com) on 2017-02-07T15:48:52Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) SANTOS, Magda Gisela Cruz dos.pdf: 956056 bytes, checksum: 52167dd29e703cec52cadaba505fad4b (MD5) / Approved for entry into archive by Simone Maisonave (simonemaisonave@hotmail.com) on 2017-02-07T21:09:12Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) SANTOS, Magda Gisela Cruz dos.pdf: 956056 bytes, checksum: 52167dd29e703cec52cadaba505fad4b (MD5) / Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-02-24T19:44:13Z (GMT) No. of bitstreams: 2 SANTOS, Magda Gisela Cruz dos.pdf: 956056 bytes, checksum: 52167dd29e703cec52cadaba505fad4b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2017-02-24T20:03:14Z (GMT). No. of bitstreams: 2 SANTOS, Magda Gisela Cruz dos.pdf: 956056 bytes, checksum: 52167dd29e703cec52cadaba505fad4b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2014-03-31 / Sem bolsa / A educação integral, quando vinculada à perspectiva da formação onilateral, é uma das categorias centrais das propostas de educação que têm por horizonte a emancipação humana. Recentemente a categoria de educação integral vem sendo incorporada às políticas educacionais através do Programa Mais Educação. A pesquisa investigou as contradições presentes na concepção de educação integral difundida pelo referido Programa tendo como perspectiva de análise a categoria de formação onilateral. Com base teórico-metodológica no materialismo histórico dialético, a pesquisa realizada, a partir de um estudo de caso, em uma escola municipal de Pelotas, analisou criticamente a concepção de educação integral difundida pelos documentos do Programa e apresentada nas falas e práticas dos profissionais envolvidos com o mesmo no contexto investigado. Como principais resultados observou-se que a educação integral proposta pelo Mais Educação difere fundamentalmente da concepção de educação integral na perspectiva da formação onilateral por vincular-se ao projeto de reorganização do padrão de acumulação do capital, constituindo-se como um espaço de construção de consenso em torno do projeto de sociedade vigente. Entretanto, a retomada desse tema nas escolas públicas pode constituir-se também como um espaço de disputa, resistência e construção de outra hegemonia, desde que a proposta de educação integral seja reelaborada e vinculada com a perspectiva da formação onilateral e da emancipação social. / Integral education, when linked to the perspective of omnilateral formation, is one of the central categories of the education proposals that have as horizon human emancipation. Recently the integral education categorie has been incorporated to the educational policies through the Program More Education (Mais Educação, in Portuguese). The research investigated the contradictions present in the conception of integral education difused by the Program More Education having as analysis perspective the omnilateral formation category. With theoretical and methodological foundation in the dialetic historic materialism, the conducted research, from a case study, in a municipal school of Pelotas, analysed critically the conception of integral education difused by the documents of the Program and showed in the speeches and practices of the professionals involved with it in the investigated context. As main results it was observed that the integral education proposed by the Program differs fundamentally from the conception of integral education in the perspective of the omnilateral formation since it is linked to the project of reorganization of the capital accumulation standard, constituting a space of construction of consense around the actual society project. However, returning to this theme in public school can become also a space of dispute, resistance and construction of another hegemony, once the integral education proposal is elaborated again and linked to the perspective of the omnilateral formation and of social emancipation.
503

A implementação do macrocampo cultura, artes e educação patrimonial do programa mais educação em uma escola da rede municipal de Juiz de Fora

Fernandes, Maria Aparecida 02 December 2014 (has links)
Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-01-20T13:10:16Z No. of bitstreams: 1 mariaaparecidafernandes.pdf: 799916 bytes, checksum: d37c09114197e02669a193f20c803a50 (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-01-25T18:02:19Z (GMT) No. of bitstreams: 1 mariaaparecidafernandes.pdf: 799916 bytes, checksum: d37c09114197e02669a193f20c803a50 (MD5) / Made available in DSpace on 2016-01-25T18:02:19Z (GMT). No. of bitstreams: 1 mariaaparecidafernandes.pdf: 799916 bytes, checksum: d37c09114197e02669a193f20c803a50 (MD5) Previous issue date: 2014-12-02 / O presente trabalho apresenta o Programa Mais Educação, que constitui uma estratégia do Governo federal para ampliar a jornada escolar. Nesse contexto, tem por objetivo analisar a implementação do macrocampo Cultura, Artes e Educação Patrimonial em uma escola da rede municipal de ensino de Juiz de Fora/MG, aqui denominada Escola A, que aderiu ao Programa em 2010, ano inicial de implantação no município. A infrequência dos alunos dos anos finais do ensino fundamental nas atividades culturais foi um dos entraves observados no contexto escolar, fato que chamou nossa atenção a ponto de buscarmos compreender os motivos dessa infrequência. Para tanto, a pesquisa recorreu à análise documental, à entrevista com os responsáveis pela equipe gestora e pelas atividades do Programa na instituição e à aplicação de questionários aos alunos inscritos nas atividades do referido macrocampo. Uma análise qualitativa foi feita a partir dos dados levantados na pesquisa, em diálogo com outras experiências sobre educação integral. Essa análise nos revelou que grande parte dos alunos não frequentam as atividades oferecidas pela escola por essas não serem obrigatórias e, principalmente, porque os pais precisam de seu auxílio em casa. A partir disto, propomos plano de intervenção que visa a melhorar a organização e a dinâmica das atividades do macrocampo Cultura, Artes e Educação Patrimonial, adequando-as às características do contexto escolar e almejando solucionar e/ou aumentar a participação dos alunos dos anos finais do ensino fundamental nessas atividades. / This paper presents the More Education Program - which is a strategy of the federal government to extend the school day. In this context, aims to analyze the implementation of macrocampo Culture, Arts and Heritage Education in a school of municipal schools of Juiz de Fora / MG, here called The School, which joined the program in 2010, the initial year of implementation in the municipality. The infrequency of the students of the final year of primary education in cultural activities was one of the barriers observed in the school context, a fact that drew our attention to the point of seeking to understand the reasons for this infrequency. To this end, the research turned to documentary analysis, interviews with those responsible for managing the staff and activities of the program in the institution and the application questionnaires to students enrolled in the activities of macrocampo said. A qualitative analysis was made from the data collected in the survey, in dialogue with other experiences on comprehensive education. This analysis has revealed that most students do not attend activities offered by the school and these are not mandatory, mainly because parents need their help at home. From this, we propose the intervention plan aimed at improving the organization and dynamics of the activities of macrocampo Culture, Arts and Heritage Education, adapting them to the characteristics of the school environment and aiming to solve and / or increase the participation of students in the final years of elementary school in these activities.
504

Associação entre as variáveis da monitorização ambulatorial da pressão arterial e a ocorrência de eventos cardiovasculares em octogenários com hipertensão arterial controlada / Association between ambulatory monitoring blood pressure variables and occurrence of cardiovascular events among octogenarians with controlled arterial hypertension

Solange de Sousa Andrade 13 August 2009 (has links)
Introdução: Nos estudos sobre hipertensão em idosos, a população participante é predominantemente da faixa etária entre 60 e 79 anos enquanto aqueles mais de 80 anos pouco participam destes estudos. Nos ensaios clínicos, a monitorização ambulatorial da pressão arterial tem-se mostrado útil no acompanhamento clínico da hipertensão arterial, porém foi empregada indivíduos relativamente jovens e suas variáveis mostram valor preditivo maior para eventos cardiovasculares que a medida da pressão arterial no consultório Objetivo: avaliar hipertensos octogenários tratados com valores de pressão arterial no consultório iguais e inferiores à 140x90 mmHg e as variáveis obtidas pela MAPA e associá-las com a ocorrência de eventos cardiovasculares e cerebrovasculares. Métodos: participaram 126 octogenários hipertensos em tratamento nos últimos 3 meses e idade mediana de 83 anos. A pressão arterial no consultório foi verificada na posição sentada, supina e ortostática como também foram obtidos informações sobre comorbidades, fatores de risco cardiovasculares e medicações. Em seguida, os pacientes foram submetidos à MAPA. Esses idosos foram acompanhados no período de 23 ±5,6 meses em média e uma consulta a cada 6 meses a fim de obter informações da ocorrência de eventos cardiovasculares. Resultados: A população foi composta de 62,7% de mulheres e as doenças mais prevalentes foram a doença arterial coronariana (33,3%), o diabete melito (23,8%) e a insuficiência cardíaca (22,2%). Dentre os anti-hipertensivos, os mais utilizados foram o inibidores da enzima de conversão de angiotensina (62,7%), os diuréticos (57,9%) e os bloqueadores beta -adrenérgicos (41,3%). No consultório e na posição sentada, a média da pressão arterial foi de 130,9±9,2 mmHg x 73,3±8,9 mmHg. A hipotensão ortostática esteve presente em 31,7% dos idosos estudados. Na MAPA, a média da pressão arterial na vigília foi de 127,1±6,5 x 69,1±8,5 mmHg e durante o sono 122,8 ± 17,3 x 62,9 ± 10,4 mmHg. Para analisar as variáveis obtidas no consultório na MAPA associadas à eventos cardiovasculares, a amostra foi dividida em um grupo com e sem eventos. Durante o seguimento, ocorreram doze eventos cardiovasculares (6 coronarianos e 6 cerebrovasculares). No grupo com eventos, é significativamente maior a prevalência de AVC prévio (33.3% vs. 7.0%, p=0.016). Os fatores de risco cardiovasculares foram similares em ambos os grupos. Também, não houve diferença entre os grupos quanto às classes de anti-hipertensivos. Na análise multivariada, a carga pressórica sistólica diurna e acidente vascular cerebral prévio foram as variáveis independentes para a ocorrência de eventos cardiovasculares. Realizado um modelo de regressão logística ajustado com as variáveis AVC e carga pressórica sistólica na vigília com ponto de corte em 35% obteve-se as seguintes razão de chances (OR) e intervalos de confiança : AVC (OR: 7,669; IC: 1,629-36,098; p = 0,009) e carga pressórica sistólica na vigília (OR: 6,752; IC: 1,750; IC: 26,051; p = 0,005), sensibilidade de 66,7%, especificidade de 75,4%, valor preditivo negativo de 95,6% e acurácia de 74,6%. Conclusão: A carga pressórica sistólica diurna maior que 35% foi forte preditor de eventos cardiovasculares em octogenários hipertensos controlados, principalmente quando associado a AVC prévio / Introduction: In studies on hypertension among the elderly, the participating population is predominantly in the 60-79 year age group, while those over 80 account for an insignificant number in these studies. The evaluation of antihypertensive treatment effect has been based mainly on office BP. However, several studies have indicated that 24-hour ambulatory blood pressure monitoring (ABPM) is a better predictor of cardiovascular events than office blood pressure (BP). The objective of this study was to evaluate the variables obtained by AMBP and associate them with the occurrence of cardiovascular and cerebrovascular events among treated hypertensive octogenarians patients with blood pressure values in the office equal to or lower than 140x90 mmHg. Methods: We included 126 hypertensive elderly octogenarian (age 83.8±3.4 years) outpatients with stable antihypertensive drug treatment for at least 3 months in the office. Values of blood pressure were measured with the patient in the seated, supine and orthostatic positions as well as data about cardiovascular risk factors, comorbidities, and medications were collected. The patients were submitted to AMBP and were followed-up for an average period of 23 ±5.6 months to obtain information on the occurrence of cardiovascular events. Results: The population consisted of 62.7% women and the most prevalent diseases were coronary arterial disease (33.3%), diabetes mellitus (23.8%) and cardiac insufficiency (22.2%). Of the antihypertensive drugs, the most commonly used were angiotensin-converting enzyme inhibitors (62.7%), diuretics (57.9%) and beta-adrenergic blockers (41.3%). In the office, the average blood pressure in the seated position was 130.9±9.2 mmHg x 73.3±8.9 mmHg. Orthostatic hypotension was present in 31.7% of the elderly patients studied. In the AMBP, the average awake blood pressure was 127.1±6.5 x 69.1±8.5 mmHg, while the average during sleep was 122.8 ± 17.3 x 62.9 ± 10.4 mmHg. Twelve cardiovascular events occurred (6 coronary and 6 cerebrovascular). To analyze the variables obtained in the office and the AMBP variables associated with cardiovascular events, the sample was divided into one group with events and a group without. In the group with events, the prevalence of previous stroke was significantly higher (33.3% vs. 7.0%, p=0.016). The cardiovascular risk factors were similar in both groups. Also, there was no difference between the groups in relation to the classes of antihypertensive drugs. In the multivariate analysis, daytime systolic pressure load and previous stroke were the independent variables for the occurrence of cardiovascular events. A logistical regression model was carried out, adjusted with the stroke variables and daytime systolic pressure load and a cut-off point of 35%, the following odds ratios and confidence intervals were obtained: stroke (OR: 7.669; IC: 1.629-36.098; p = 0.009) and daytime systolic pressure load (OR: 6.752; IC: 1.750; IC: 26.051; p = 0.005), sensitivity 66.7%, specificity 75.4%, negative predictive value 95.6% and accuracy 74.6%. Conclusion: Daytime systolic pressure load higher than 35% was a strong predictor of cardiovascular events in controlled hypertensive octogenarians, particularly when associated with previous stroke
505

Konzeption und Aufbau eines Medienüberwachnungs- und Meldesystems

Feige, Lutz 19 September 2001 (has links)
Diese Arbeit erörtert die Realisierungsmöglichkeiten der Überwachung von technischen Medien am Institut für Physik der TU Chemnitz und entwickelt daraus ein universell einsetzbares offenes System. Das aus dem Entwurf heraus mit ingenieurtechnischen Mitteln realisierte Medien-Ausfall- und Informations-System (_M_A_i_S_) ermöglicht die Überwachung von 16 Ereignissen an Ruhe- oder Arbeitsstromkreisen. Mit Hilfe einer Nutzerdatenbank können interessierte Teilnehmer über Ereignisänderungen differenziert informiert werden. Die Information gelangt dabei per Funknachricht über öffentliche Nachrichtensysteme oder als Electronic Mail zum Teilnehmer. Parallel dazu kann über das World-Wide-Web online der Status aller 16 Ereigniskanäle und der zeitliche Verlauf der Ereignisse eingesehen werden.
506

Simulation-Optimization of the Management of Sensor-Based Deficit Irrigation Systems

Kloß, Sebastian 11 January 2016 (has links)
Current research concentrates on ways to investigate and improve water productivity (WP), as agriculture is today’s predominant freshwater consumer, averaging at 70% and reaching up to 93% in some regions. A growing world population will require more food and thus more water for cultivation. Regions that are already affected by physical water scarcity and which depend on irrigation for growing crops will face even greater challenges regarding their water supply. Other problems in such regions are a variable water supply, inefficient irrigation practices, and over-pumping of available groundwater resources with other adverse effects on the ecosystem. To face those challenges, strategies are needed that use the available water resources more efficiently and allow farming in a more sustainable way. This work focused on the management of sensor-based deficit irrigation (DI) systems and improvements of WP through a combined approach of simulation-optimization and irrigation experiments. In order to improve irrigation control, a new sensor called pF-meter was employed, which extended the measurement range of the commonly used tensiometers from pF 2.9 to pF 7. The following research questions were raised: (i) Is this approach a suitable strategy to improve WP; (ii) Is the sensor for irrigation control suitable; (iii) Which crop growth models are suitable to be part of that approach; and (iv) Can the combined application with experiments prove an increase of WP? The stochastic simulation-optimization approach allowed deriving parameter values for an optimal irrigation control for sensor-based full and deficit irrigation strategies. Objective was to achieve high WP with high reliability. Parameters for irrigation control included irrigation thresholds of soil-water potentials because of the working principle behind plant transpiration where pressure gradients are transmitted from the air through the plant and into the root zone. Optimal parameter values for full and deficit irrigation strategies were tested in irrigation experiments in containers in a vegetation hall with drip irrigated maize and compared to schedule-based irrigation strategies with regard to WP and water consumption. Observation data from one of the treatments was used afterwards in a simulation study to systematically investigate the parameters for implementing effective setups of DI systems. The combination of simulation-optimization and irrigation experiments proved to be a suitable approach for investigating and improving WP, as well as for deriving optimal parameter values of different irrigation strategies. This was verified in the irrigation experiment and shown through overall high WP, equally high WP between deficit and full irrigation strategies, and achieved water savings. Irrigation thresholds beyond the measurement range of tensiometers are feasible and applicable. The pF-meter performed satisfactorily and is a promising candidate for irrigation control. Suitable crop models for being part of this approach were found and their properties formulated. Factors that define the behavior of DI systems regarding WP and water consumption were investigated and assessed. This research allowed for drawing the first conclusions about the potential range of operations of sensor-based DI systems for achieving high WP with high reliability through its systematical investigation of such systems. However, this study needs validation and is therefore limited with regard to exact values of derived thresholds.
507

Mechanismus und Regulation der subzellulären Lokalisation von Saccharose-Synthase

Holtgräwe, Daniela L. 31 October 2005 (has links)
Die vorliegende Arbeit beschäftigt sich mit verschiedenen Aspekten der Assoziation von Saccharose-Synthase (SUS) mit subzellulären Strukturen. Durch cDNA-Durchmusterungen konnten proteinogene Bindepartner von SUS sowie Aktin identifiziert und zum Teil verifiziert werden. Die dritte Isoform SuS3 aus Mais wurde auf molekularer Ebene identifiziert und das rekombinante Protein biochemisch charakterisiert. Trotz signifikanter Sequenzunterschiede zwischen den SUS-Isoformen, wurden ähnliche katalytische Eigenschaften und mögliche posttranslationale Modifikationen der Enzyme nachgewiesen, darunter die Redox-Modifikation der Enzymaktivität und das Potential zur reversiblen Phosphorylierung. Der Einfluss der Phoshorylierung von SUS auf dessen enzymatische und assoziative Aktivität wurde mittels mutagenisiertem Protein untersucht und zeigte kein stark verändertes Verhalten infolge der Mutationen. Eine metabolische Regulation der SUS-Aktin-Wechselwirkung durch Zucker konnte bestätigt und die katalytische Aktivität von SUS in Gegenwart von Aktin gezeigt werden. Assoziationsstudien von Aktin mit synthetischen Peptiden sowie immunologische Untersuchungen lieferten Hinweise für die Aktinbindedomäne in SUS. Co-Pelletierungsexperimente zeigten die Assoziation von SUS mit Mikrotubuli aus Rinderhirn. In vitro konkurriert SUS mit Aldolase um die Bindung an Miktotubuli. Als proteinogene Bindepartner von SUS wurden einige im Kohlenhydratstoffwechsel sowie im 26S-Proteasom-Komplex involvierte Proteine identifiziert. Ebenso wurde eine Glutathion-Peroxidase identifiziert, die ubiquitäre Transkriptakkumulation dokumentiert und die katalytische Aktivität des rekombinanten Proteins gezeigt. Eine weitere cDNA-Durchmusterung führte zur Identifikation verschiedener glykolytischer Enzyme als potentielle Interaktionspartner von Mais-Aktin sowie zu Bindepartnern, die nach Sequenzanalyse Domänen mit Homologien zu bekannten ABPs aus tierischen Organismen zeigten.
508

[pt] CONCEITOS CENTRAIS E COMPONENTIZAÇÃO DE DIAGRAMAS DE CLASSE UML REPRESENTADOS EM GRAFO / [en] CORE CONCEPTS AND COMPONENTIZATION OF UML CLASS DIAGRAMS REPRESENTED IN GRAPH

23 December 2021 (has links)
[pt] O objetivo do trabalho é o desenvolvimento de uma aplicação web capaz de realizar diferentes análises de diagramas UML. Umas dascaracterísticas da ferramenta é a compatibilidade com outras ferramentas de edição de diagramas UML. Para isto, foi implementado um parser genérico XMI que importa driagramas de classe e gera um grafo orientado equivalente. Com a posse do grafo, são realizados estudos capazes de adicionar informações extras aos diagramas. O primeiro estudo é a identificação de quais clases compõesm o core concept (classes de alta importância para o sistema). Outro estudo é a clusterização deste grafo a fim de agrupar classes em propostas de componentes. Por fim, são discutidas estimativas de importância, do grau de coesão, além de métricas de acoplamento e tamanho do diagrama como um todo e dos componetes gerados. / [en] The goal of this dissertation is to develop a web application that explores different analysis of UML diagrams. One of the main features of this tool is the compatibility with other tools that create UML diagrms. In order to do that, we implemented a generic XMI parser that import class diagrams and provides as result a directed graph. With this graph in hand, we conducted studies that provide extra information regrading this diagram. The first study is the identification of the classes that can be considered core concepts (defining the important classes of the system). The other study permorms graph clustering, aiming to create groups pf classes, making it possible to generate components. Finally, we discuss estimates of importance and degree of cohesion, as well as size and coupling metrics of the diagram as a whole and the generated components.
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Nachweismethode für eine grünlandbasierte Fütterung: Untersuchung von 13C im Rinderhaar zur Bestimmung des Maisanteils in der Ration sowie zur Eignung als quantitativer Nachweis einer grünlandbasierten Fütterung

Kesting, Stefan 25 October 2022 (has links)
In einer Praxisstudie wurde geprüft, ob die Stabilisotopenanalyse von Rinderhaarproben ein praxistaugliches Verfahren darstellt, um retrospektiv auf die Zusammensetzung des Futters zu schließen. Es konnte bestätigt werden, dass es einen sehr starken Zusammenhang zwischen dem Delta-13-C-Wert im Haar und dem Maisanteil in der Fütterung gibt. Darüber lässt sich auch der Grasanteil in der Ration abschätzen. Die Publikation richtet sich an das Fachpublikum sowie die interessierte Öffentlichkeit. Redaktionsschluss: 22.02.2022
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[pt] OS PRINCÍPIOS DA PRODUÇÃO MAIS LIMPA COMO FERRAMENTA DE PRÁTICAS MAIS SUSTENTÁVEIS EM PEQUENOS MEIOS DE HOSPEDAGEM / [en] THE PRINCIPLES OF CLEANER PRODUCTION AS A TOOL FOR MORE SUSTAINABLE PRACTICES IN SMALL HOTELS

ANA CRISTINA DA SILVA COSTA 25 September 2023 (has links)
[pt] O turismo como uma atividade econômica e um fenômeno social, que tem um enorme potencial como ferramenta para proteção do meio ambiente, assim como, para erradicação da pobreza. Tem-se hoje uma atividade turística promissora, com um turista mais cauteloso em suas escolhas, usufruindo de um turismo mais saudável e responsável. Neste contexto, pensando o meio de hospedagem como um equipamento turístico, que tem de estar alinhado a esse novo turismo responsável, os empreendimentos hoteleiros devem estar dispostos a adotar práticas, que objetivem a melhoria do seu desempenho diante das questões ambientais sociais e econômicas. Nesta perspectiva, a Produção mais Limpa (P+L), vem como uma ferramenta que aplicada a empresas dos mais variados segmentos, através de uma estratégia econômica e socioambiental, mostrando-se como uma alternativa viável e interessante para os gestores, que vislumbram a melhoria dos seus processos produtivos. Assim, este trabalho tem por objetivo o estudo de viabilidade de implantação da Produção mais Limpa em um pequeno meio de hospedagem localizado na praia de Vilatur em Saquarema- RJ, visando trazer benefícios importantes ao empreendimento no que se refere aos aspectos ambientais, econômicos e sociais, assim como, utilizar esse estudo como um piloto para que a proposta possa ser multiplicada para adesão em outros meios de hospedagem do município. / [en] Tourism as an economic activity and a social phenomenon, which has a big potencial as a tool for protecting the environment, as well as, for eradicating poverty. Today, there is a promising tourist activity, with tourists who are more cautions in their choices, enjoying healthier and responsible tourism. In this context, considering the accommodation as a tourist equipment, which must be aligned with this new responsible tourism, hotel enterprises must be willing to adopt practices that aim to improve their performance in the face of environmental, social and economic issues. In this perspective, Cleaner Production (CP) comes as a tool that can be applied to companies in the most varied segments, through an economic and socio-environmental strategy, proving to be a viable and interesting alternative for managers, who envision the improvement of its production processes. Thus, this work aims to study the feasibility of implementing Cleaner Production in a small accommodation located on Vilatur beach in Saquarema – RJ, aiming to bring important benefits to the enterprise in terms of environmental, economic and social aspects, as well as using this study as a pilot so that the proposal can be multiplied for adherence to other small hotels in the city.

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