Although Anne Brontë's first novel, Agnes Grey, presents itself as a didactic treatise, Brontë's work departs from many accepted Evangelical tropes in the portrayal of its moral protagonist. These departures create an exemplary figure whose flaws potentially subvert the novel's didactic purposes. The character of Agnes is not necessarily meant to be directly emulated, yet Brontë's governess is presented as a tool of moral instruction. The conflict between the novel's self-proclaimed didactic purpose and the form in which it presents that purpose raises a number of interpretive questions. I argue that many of these questions can be answered through the application of a hermeneutic presented in Augustine's De Doctrina Christiana. Such a hermeneutic shifts the burden of interpretation away from the author and toward the reader in such a way that the moral figure becomes, not a standard to be emulated, but rather a test of the reader's personal spiritual maturity. This sign theory heavily influenced the works of medieval hagiographers such as Ælfric of Enysham, who depended on Augustine's sign theory to mediate some of the less-orthodox behaviors of saints such as Æthelthryth of Ely. I argue that by applying Augustine's hermeneutic and reading Agnes Grey in the context of these earlier didactic genres, the novel's potentially subversive qualities are not only neutralized, but become an important element of Evangelical instruction.

Die Prozesse der stetigen, interaktiven und lokalen Herstellung der Alltagswirklichkeit zu untersuchen, ist das Anliegen der Ethnomethodologie, die dem interpretativen Paradigma der Soziologie zugerechnet wird. Ihre leitende Frage lautet: Welcher Praktiken bedienen sich Gesellschaftsmitglieder, um die geordnete Struktur ihrer Alltagswelt interaktiv hervorzubringen? Geschlecht wird entsprechend als ein interaktiv hergestelltes Merkmal sozialer Ordnung begriffen.

The work deals with St. Agnes Convent as a cultural and historical monument and possibilities of using a cultural and historical landmark, specifically St. Agnes Convent, in classes of Citizenship. It aims at exploring cultural and historical benefits of this convent from the view of its functions in the past and present, at making use of these findings to judge the importance of these functions for landmark value and preservation of the convent and finally at considering suitability of this monument for Citizenship at Stage 2 of basic schools, including proposals of specific activities. The author discusses the importance of teaching relation to cultural and historical heritage, to monuments and their conservation and also possibilities of its development owing to Citizenship and educational conception of the Czech Republic and related documents (especially "RVP" [Framework Educational Programmes for Basic Education] and "ŠVP" [School Educational Programmes]). Introducing the evolution of preservation of monuments in the Czech Republic, the author acquaints readers with approach to preservation of landmarks in the past and today and with problems of preservation of monuments which opens space for teachers and their students for reflection of their own relation to monuments and possibilities of...

O objetivo deste trabalho consistiu em esclarecer os mecanismos bioquímicos e hormonais da ação da somatotropina recombinante bovina (r-bST), recomendada no tratamento de toxemia da prenhez (TP). Para tal, foram realizados dois experimentos nos quais induziram-se quadros de hipercetonemia ou hiperlipidemia em 39 ovelhas com elevada condição corporal tratadas ou não previamente com 160 mg de um produto comercial de r-bST, pela via subcutânea. A hipercetonemia foi provocada pela infusão IV de 5 mM/kg P.V. de beta hidroxibutirato (BHB) no decorrer de duas horas e a hiperlipidemia com injeção IV de solução 20% de óleo de peixe, perfazendo 0,54g de triacilglicerol/kg P.V. no decorrer de quatro dias. Essas quantidades infundidas lograram provocar os quadros esperados. No primeiro experimento, o tratamento com r-bST promoveu aumento significativo da gliconeogênese por meio da conversão de BHB em glicose, maiores teores de insulina, com consequente aumento da resistência insulínica, incremento na concentração de IGF1 que levou a mobilização de nitrogênio ureico para os depósitos e maior atividade de GGT. No segundo experimento, o rbST gerou destacado aumento da gliconeogênese, pela metabolização dos AGNEs e de BHB em glicose, com maior destaque aos AGNEs, elevação dos teores de insulina e do percentual de resistência insulínica, e maior atividade da AST e GGT e bilirrubinal direta e total. Assim, conclui-se que a atuação farmacológica do r-bST se baseia na vigorosa capacidade do aumento da gliconeogênese, diminuindo concomitantemente os nefastos catabólitos (AGNEs e BHB) no processo da TP. Foi realizado ainda um experimento subsidiário para comparar a capacidade diagnóstica da detecção de BHB, em sangue total, entre o kit diagnóstico enzimático (Randox®), padrão ouro, e tiras reativas comerciais (Precision Xceed®) lidas em dosímetro portátil. Foram obtidas 247 amostras de sangue das ovelhas nas quais tinham sido infundida solução de BHB, no experimento um. Duas faixas de acetonemia foram consideradas: de 0,7 a 1,5 mM caracterizada como cetose inaparente e acima deste valor como cetose clínica. A correlação entre os métodos foi alta (r = 0,98 ; P < 0,001). Na cetose inaparente as tiras reativas apresentaram sensibilidade de 0,97 e especificidade de 0,89 e na cetose aparente sensibilidade de 0,99 e especificidade de 0,75, respectivamente. As tiras reativas podem ser empregadas eficientemente no diagnóstico precoce de casos de TP, com custo baixo e rápida leitura ao pé dos animais. / The aim of this study was to clarify the biochemical and hormonal mechanisms of action of recombinant bovine somatotropin (r-bST), recommended in the treatment of pregnancy toxemia (PT). Two experiments were conducted inducing hyperlipidemia or hyperketonemia in 39 high body condition sheep pretreated or no with 160 mg of a commercial product of rbST subcutaneously. The hyperketonemia was caused by IV infusion of 5 mM / kg BW of beta-hydroxybutyrate (BHB) during two hours and hyperlipidemia with IV injection of a 20% fish oil solution corresponding to 0.54 g of triglyceride / kg BW in four days course. These infusions successfully caused the expected effects. In the first experiment, treatment with rbST caused a significant increase of gluconeogenesis by converting BHB into glucose, higher levels of insulin, with consequent increased insulin resistance, increase in the concentration of IGF1 leading to mobilization of urea nitrogen for deposits and increased activity of GGT. In the second experiment, the r-bST greatly increased gluconeogenesis generated by metabolism of non esterified fatty acids (NEFA), BHB and glucose, with emphasis on NEFA, elevated levels of insulin and the percentage of insulin resistance, and increased activity of AST and GGT and bilirrubin direct and total. In conclusion, the pharmacological action of r-bST is based on vigorous increase capacity on gluconeogenesis, concomitantly reducing the adverse catabolites (NEFA and BHB) in the PT process. An additional experiment was performed to compare the diagnostic capability of detecting BHB in whole blood, between the enzymatic diagnostic kit (Randox®), considered gold standard, and commercial test strips (Precision Xceed®) read in hand-held meter. 247 sheep blood samples were obtained in the first experiment in which BHB solution had been infused. Two ketonemic tracks were considered: 0.7 to 1.5 mM characterized as unapparent ketosis and above this value as a clinical ketosis. The correlation between the methods was high (r = 0.98, P <0.001). In test strips method, ketosis unapparent showed sensitivity of 0.97 and specificity of 0.89 and in ketosis apparent sensitivity of 0.99 and specificity of 0.75, respectively. The test strips can be used efficiently in the early diagnosis of cases of TP, with fast reading and low cost.

The aim of this thesis is to study representations of identity and (in)visibility in Swedish lesbian novels written in the 1930s, and to provide a summary of Swedish lesbian literature up to the early 21st century. This study has been done through a close reading primarily of Charlie by Margareta Suber (1932), Fröknarna von Pahlen by Agnes von Krusenstjerna (1930–1935) and Kris by Karin Boye (1934). Lesbian literature is discussed as a loose category, a construction which can be used as an analytical tool in a conscious and reflexive way, with its basis in the categories of author, text and reader. In short, I define lesbian literature as novels written by women, about lesbian figures and/or relationships, and for lesbian readers in the sense that the literature depicts lesbians from an insider’s perspective. As regards the period before 1930, the focus is on romantic friendship and the excitement zone when the romantic friendship becomes a sexual one, as seen in the fictitious case of Sin fars dotter (1920) by Lydia Wahlström. Sexological theories, the image of “the new woman” and changes to the law all colour the first half of the 20th century. This is seen in Charlie by Margareta Suber, where the author makes use of many such explanations in her creation of a lesbian figure. A reading of Fröknarna von Pahlen by Agnes von Krusenstjerna shows an intricate pattern of relationships at its heart. My analysis charts several same-sex couples, a lesbian single woman and two collectives; that is to say, the female collective and the male homosexual collective. The relationships between women are many-faceted and include everything from romantic friendship, kinship and sensualism to eroticism and shared parenthood. In my analysis of Kris by Karin Boye, I focus on Malin, the main character, and the development of her sense of identity, in which the struggle between the language of the world around her and her own emotional experience of love for a woman is a central theme. After the 1930s, the historical context changed in terms of everything from decriminalisation in 1944 via the homophobic panic of the 1950s to the impact of queer theory in the 1990s. Swedish lesbian literature addresses everything from crime of passion (murder) to the coming out process of young women. There exists in all novels from the 1930s an interplay that is (in)visible: the characters or lesbian relationships depicted are both visible and invisible at the same time. The characters are more or less aware of the potential risks attached to being visible as a lesbian, and often they do not notice themselves when this occurs. During the course of the 20th century, (in)visibility becomes replaced by openness and secrecy, and the visibility of the lesbian characters is politicised. / The abstract is translated by Janet French.

Univ., Diss.--Zürich, 2003.

O objetivo deste trabalho consistiu em esclarecer os mecanismos bioquímicos e hormonais da ação da somatotropina recombinante bovina (r-bST), recomendada no tratamento de toxemia da prenhez (TP). Para tal, foram realizados dois experimentos nos quais induziram-se quadros de hipercetonemia ou hiperlipidemia em 39 ovelhas com elevada condição corporal tratadas ou não previamente com 160 mg de um produto comercial de r-bST, pela via subcutânea. A hipercetonemia foi provocada pela infusão IV de 5 mM/kg P.V. de beta hidroxibutirato (BHB) no decorrer de duas horas e a hiperlipidemia com injeção IV de solução 20% de óleo de peixe, perfazendo 0,54g de triacilglicerol/kg P.V. no decorrer de quatro dias. Essas quantidades infundidas lograram provocar os quadros esperados. No primeiro experimento, o tratamento com r-bST promoveu aumento significativo da gliconeogênese por meio da conversão de BHB em glicose, maiores teores de insulina, com consequente aumento da resistência insulínica, incremento na concentração de IGF1 que levou a mobilização de nitrogênio ureico para os depósitos e maior atividade de GGT. No segundo experimento, o rbST gerou destacado aumento da gliconeogênese, pela metabolização dos AGNEs e de BHB em glicose, com maior destaque aos AGNEs, elevação dos teores de insulina e do percentual de resistência insulínica, e maior atividade da AST e GGT e bilirrubinal direta e total. Assim, conclui-se que a atuação farmacológica do r-bST se baseia na vigorosa capacidade do aumento da gliconeogênese, diminuindo concomitantemente os nefastos catabólitos (AGNEs e BHB) no processo da TP. Foi realizado ainda um experimento subsidiário para comparar a capacidade diagnóstica da detecção de BHB, em sangue total, entre o kit diagnóstico enzimático (Randox®), padrão ouro, e tiras reativas comerciais (Precision Xceed®) lidas em dosímetro portátil. Foram obtidas 247 amostras de sangue das ovelhas nas quais tinham sido infundida solução de BHB, no experimento um. Duas faixas de acetonemia foram consideradas: de 0,7 a 1,5 mM caracterizada como cetose inaparente e acima deste valor como cetose clínica. A correlação entre os métodos foi alta (r = 0,98 ; P < 0,001). Na cetose inaparente as tiras reativas apresentaram sensibilidade de 0,97 e especificidade de 0,89 e na cetose aparente sensibilidade de 0,99 e especificidade de 0,75, respectivamente. As tiras reativas podem ser empregadas eficientemente no diagnóstico precoce de casos de TP, com custo baixo e rápida leitura ao pé dos animais. / The aim of this study was to clarify the biochemical and hormonal mechanisms of action of recombinant bovine somatotropin (r-bST), recommended in the treatment of pregnancy toxemia (PT). Two experiments were conducted inducing hyperlipidemia or hyperketonemia in 39 high body condition sheep pretreated or no with 160 mg of a commercial product of rbST subcutaneously. The hyperketonemia was caused by IV infusion of 5 mM / kg BW of beta-hydroxybutyrate (BHB) during two hours and hyperlipidemia with IV injection of a 20% fish oil solution corresponding to 0.54 g of triglyceride / kg BW in four days course. These infusions successfully caused the expected effects. In the first experiment, treatment with rbST caused a significant increase of gluconeogenesis by converting BHB into glucose, higher levels of insulin, with consequent increased insulin resistance, increase in the concentration of IGF1 leading to mobilization of urea nitrogen for deposits and increased activity of GGT. In the second experiment, the r-bST greatly increased gluconeogenesis generated by metabolism of non esterified fatty acids (NEFA), BHB and glucose, with emphasis on NEFA, elevated levels of insulin and the percentage of insulin resistance, and increased activity of AST and GGT and bilirrubin direct and total. In conclusion, the pharmacological action of r-bST is based on vigorous increase capacity on gluconeogenesis, concomitantly reducing the adverse catabolites (NEFA and BHB) in the PT process. An additional experiment was performed to compare the diagnostic capability of detecting BHB in whole blood, between the enzymatic diagnostic kit (Randox®), considered gold standard, and commercial test strips (Precision Xceed®) read in hand-held meter. 247 sheep blood samples were obtained in the first experiment in which BHB solution had been infused. Two ketonemic tracks were considered: 0.7 to 1.5 mM characterized as unapparent ketosis and above this value as a clinical ketosis. The correlation between the methods was high (r = 0.98, P <0.001). In test strips method, ketosis unapparent showed sensitivity of 0.97 and specificity of 0.89 and in ketosis apparent sensitivity of 0.99 and specificity of 0.75, respectively. The test strips can be used efficiently in the early diagnosis of cases of TP, with fast reading and low cost.

Anne Brontë died in 1848, having written two novels, Agnes Grey (1847) and The Tenant of Wildfell Hall (1848). Although these novels, especially The Tenant of Wildfell Hall, initially received a favourable critical response, the unsympathetic remarks of Charlotte Brontë and Elizabeth Gaskell initiated a dismissive attitude towards Anne Brontë’s work. For over a hundred years, she was marginalized and silenced by a critical world that admired and respected the work of her two sisters, Charlotte and Emily, but that refused to acknowledge the substantial merits of her own fiction. However, in 1959 revisionist scholars such as Derek Stanford, Ada Harrison and Winifred Gérin, offered important, more enlightened readings that helped to liberate Brontë scholarship from the old conservatisms and to direct it into new directions. Since then, her fiction has been the focus of a robust, but still incomplete, revisionist critical scholarship. My work too is revisionist in orientation, and seeks to position itself within this revisionist approach. It has a double focus that appraises both Brontë’s social commentary and her narratology. It thus integrates two principal areas of enquiry: firstly, an investigation into how Brontë interrogates the position of middle class women in their society, and secondly, an examination of how that interrogation is conveyed by her creative deployment of narrative techniques, especially by her awareness of the rich potential of the first person narrative voice. Chapter 1 looks at the critical response to Brontë’s fiction from 1847 to the present, and shows how the revisionist readings of 1959 were pivotal in re-invigorating the critical approach to her work. Chapter 2 contextualizes the key legal, social, and economic consequences of Victorian patriarchy that so angered and frustrated feminist thinkers and writers such as Brontë. The chapter also demonstrates the extent to which a number of her core concerns relating to Victorian society and the status of women are reflected in her work. In Chapter 3 I discuss three important biographical influences on Brontë: her family, her painful experiences as a governess, and her reading history. Chapter 4 contains a detailed analysis of Agnes Grey, which includes an exploration of the narrative devices that help to reinforce its core concerns. Chapter 5 focuses on The Tenant of Wildfell Hall, showing how the novel offers a richer and more sophisticated analysis of feminist concerns than those that are explored in Agnes Grey. These are broadened to include an investigation of the lives of married women, particularly those trapped in abusive marriages. The chapter also stresses Brontë’s skilful deployment of an intricate and layered narrative technique. The conclusion points to the ways in which my study participates in and extends the current revisionist trend and suggests some aspects of Brontë’s work that would reward further critical attention. / Thesis (DLitt)--University of Pretoria, 2013. / gm2014 / English / Unrestricted

This study examines the female protagonist Petra von Pahlen in Agnes von Krusenstjerna’s novel Den blå rullgardinen (The blue blind). The aim of the study is to make a stylistic examination of narrative perspective, relations, and agency in several text passages from the novel, to find out how the language of the text shapes Petra von Pahlen as a female character. To see whether the linguistic choices and functions of the text form Petra as an active or passive person, her relation to four other characters in the novel are examined. The material consists of 39 passages of text taken from 10 chapters of the novel, all of which dealing specifically with Petra’s part of the story. Literary theories used for the study are narratology and systemic-functional grammar. The applied methods for analysing the passages are a selection of syntactic and semantic markers compiled by Staffan Hellberg (1985) for stylistic analysis of narrative perspective in Swedish literary texts, and a selection of the tools for investigation of transitivity and ergativity in texts available through the systemic-functional theory of grammar by Michael Halliday (2014). The results show that the narrative perspective used in the text passages are mostly internal focalization, and that the most frequently used stylistic markers are expressions for perception and reflection, similes, metaphors, and words expressing value. The results also show that Petra is most frequently realized through the participant roles of Senser in mental processes, and Goal in material processes. In the ergative analysis Petra is most frequently realized in non-ergative clauses through the participant role as Medium, both in terms of first and second participant; she is seldom realized as Agent. From the quantitative results of the study, Petra can be viewed as a passive character, however an argumentation based on previous research from the fields of literary science and feminist literary stylistics also suggests an interpretation, where the context and themes in the novel, together with an awareness of the different ‘meanings’ of linguistic features, provide a less powerless position for Petra.

The novel Agnes von Lilien by Caroline von Wolzogen, although celebrated during the period of Weimar Classicism, was not generally well known to English-speaking readers and researchers until recently. This project aims to address this situation by creating an easily accessible English translation of the novel complete with critical annotations for the benefit of researchers and lay readers alike. The annotated translation presented in this work is an excerpt of the full translation of the work drawn in particular from the first third of the novel. This novel, first published in 1798, reflects many ideals of the Enlightenment, as well as opinions on women's roles and women's education. In the introduction, I trace the way that the novel seeks to gently persuade the nobility and educated middle class to change the world around them. This is done through the ever-present contrasts filling its pages alongside the novel's emphasis on ideal possibilities. Rather than serving as a revolutionary critique, I assert that the story conveys a quiet call for a level of social reform that still assures the nobility their power while nevertheless challenging them to use that power for the betterment of society. Women are urged to extend their reach to the outer boundaries of womanhood rather than being content with the confinement imposed by traditional society. I conclude that the strength of Wolzogen's text and the trait that draws readers back even centuries later is the fact that, under the cloak of intrigue, adventure, and romance expected from the novel form, the ideals of the Enlightenment shine clearly. In spite of social and political changes over the past two centuries, the call to virtue, industry, reason, and self-improvement, regardless of gender or social class, still maintains its relevance and power for readers in the modern era.