El presente estudio nos ha permitido investigar los beneficios que brindará el aplicativo móvil de ser implementado en un proyecto de construcción. La investigación se inició identificando el problema actual en el sector construcción respecto a la dificultad en el acceso a la información sobre el estado de un proyecto y la solución que se podría dar a través de esta herramienta tecnológica. Como grupo hemos identificado que con un aplicativo móvil, los usuarios tendrán la posibilidad de mejorar sustancialmente la gestión del conocimiento e información de sus proyectos de manera rápida y oportuna. El nombre que hemos designado al aplicativo móvil del estudio realizado es: VProject, en donde “V” es la inicial de “View” en inglés y “Project” que significa proyecto. Este nombre busca mostrar a los usuarios información actualizada del proyecto de construcción en el que participa, y de esa manera les permitirá visualizar la información en tiempo real, fomentando así un mayor involucramiento con su proyecto y un seguimiento continuo en la ejecución. La estrategia de desarrollo del aplicativo es que sea amigable y sencillo para el agrado de los usuarios, y que la información sea permanentemente actualizada según sus necesidades. En cuanto al análisis costo beneficio, el estudio nos ha permitido concluir que es rentable invertir en un aplicativo móvil en un proyecto de construcción, ya que es una tecnología de la información que tiene el potencial de denotar nuevos canales de interacción entre los usuarios e interesados del mismo. Además, en los últimos años las Tecnologías de la Información (T.I) van tomando mayor protagonismo en el sector construcción de nuestro país, generando la oportunidad de introducir en el mercado un aplicativo móvil rentable y que se pueda sostener en el tiempo. Por lo antes expuesto, presentamos el siguiente estudio que describe nuestra propuesta de implementación de aplicativo móvil en proyectos de construcción. / The current study has allowed us to investigate the benefits that the mobile app will bring from being implemented in a construction project. The research began by identifying the current problem in the construction market, regarding the access information difficulty about the project status and the solution that could be given through this technological tool. As a group, we have identified that with a mobile app, users will have the opportunity to improve substantially the knowledge management and also the information of their projects in a fast and timely manner. The name that we have designed to the mobile app of the research study is: VProject, where “V” is the initial of “View” and “Project” that means project in English. This name looks for showing to the users’ updated information on the construction project in which they participate on. Also, this allows the users to see the information in real time, thus encouraging more involvement on their project and a continuous tracking in its development. The development strategy of the mobile app is to be friendly and simple for the pleasure of the users. Also, the mobile app information has to be constantly updated according to the users ‘needs. Regarding to the cost-benefit analysis, the research has allowed us to conclude that it is profitable to invest in mobile app for a construction project, since it is an information technology that has the potential to denote new ways of interaction between users and stakeholders. In addition; in recent years, Information Technologies (T.I) have taken a greater role in the construction segment of our country, thus generating the opportunity to introduce a profitable mobile app on the market that can be sustained over time. For the above reasons, we present the following research that describes our proposal to implement a mobile app in construction projects. / Tesis

Alzheimer’s disease is a neurodegenerative disease characterised by progressive memory deterioration and cognitive impairment. Pathological hallmarks are extracellular senile plaques, neurofibrillary tangles and neuron loss. Senile plaques are produced through altered processing of the membrane-bound protein APP. Different neurotransmitter signal transduction pathways have been implicated in the formation or development of Alzheimer’s pathologies, but the molecular mechanisms behind these changes are not well known. The overall aims of this thesis were to identify novel genes with differential expression in Alzheimer’s disease and to investigate mechanisms initiating these changes and their relationship to the disease. A real-time RT-PCR strategy was developed to enable detection of small mRNA changes in human brain autopsy samples. This approach was first used to investigate levels of expression of a candidate gene (MAO), and later employed to verify gene expression differences detected by cDNA microarray analysis. Of several genes verified as differentially expressed in the patients, ITPKB (Inositol 1,4,5-trisphosphate 3-kinase B) and RGS4 (Regulator of G-protein signalling 4) presented the largest expression differences in Alzheimer’s cases compared to control samples. Several splice variants of RGS4 showed similar down-regulation levels and one rare haplotype was associated with decreased RGS4 expression. Functional studies in SH-SY5Y cell cultures overexpressing RGS4 showed that it is likely that RGS4 affects APP processing by regulating PRKC expression levels. The combined expression of RGS4 and ITPKB is for the first time presented in this thesis as genes with altered mRNA levels in Alzheimer’s disease. These two genes are implicated in the same signalling pathway that modifies calcium levels in the cell. Furthermore, the fact that RGS4 affects APP processing suggests that RGS4 is involved in the development of senile plaques. This motivates further functional studies of this gene and suggests that RGS4 may become a new potential drug target for Alzheimer’s disease.

Att fjärrstyra sin värmepump gör det möjligt att styra inomhusklimatet även då man inte är hemma. Detta passar mycket bra i exempelvis fritidshus då man enkelt kan höja temperaturen innan man skall dit och därmed kan njuta av ett behagligt inomhusklimat direkt. Med dagens fjärrstyrning av Daikins värmepumpar finns två problem. Systemet använder GSM-nätet och användaren måste kunna de olika SMS-koderna utantill. Fjärrstyrning används oftast i fritidshus på landsbygden och 3G-nätet har idag bättre täckning än GSM-nätet på många av dessa platser. Målet med examensarbetet är att ta fram ett system som åtgärdar dessa problem. Vi börjar med att ta fram en funktionsmodell att utgå från. Går vidare med val av hårdvara för modulen, och därefter vidare till mjukvaruutveckling. Resultatet av detta examensarbete är ett system för fjärrstyrning av Daikins värmepumpar som använder 3G-nätet och enkelt kan styras via en androidapplikation.

MobisleApps utvecklar och underhåller en applikation för mobila enheter så som iPhone och Android som heter MobisleNotes. Denna applikation ger användaren möjlighet att skriva anteckningar i mobilen och synkronisera dessa till en extern server. MobisleApps vill erbjuda ytterligare möjligheter för användarna att skriva anteckningarna och har bestämt sig för göra detta med hjälp av en webbläsare och ett gränssnitt mot den externa servern. Detta examensarbete syftar till att ta fram ett sådant webbgränssnitt och att undersöka om detgår att använda något ur de nya standarderna för Hyper Text Markup Language (HTML) och Cascading Style Sheets (CSS). Genom att utveckla ett webbgränssnitt som ger användaren möjlighet att logga in, skapa, ändra och ta bort anteckningar som synkroniseras till telefonen via en extern server har jag uppfyllt de krav som ställdes. Slutsatsen av rapporten är att det är möjligt att använda en del nya HTML5 och CSS3 funktionalitet och egenskaper. Detta om det görs för att förstärka webbgränssnittets funktionalitet och utseende medan man inte förlitar sig på att alla användare kommer att ha en uppdaterad webbläsare. Annars är risken stor att man stänger ute användare som inte kan ellervet hur man uppdaterar sin webbläsare. / TQDT11

Mobile applications stores such as Apple’s App Store and Google’s Android Market revolutionized the distribution of applications for mobile devices. However, with thousands of application submissions, limited testing resources and the lack of an effective filtering mechanism, application stores suffer from information overload and a risk of releasing poor quality applications that could create confusion to consumers and may seriously affect the App store markets. Thus concern has been raised whether applications have been developed according to the need and interest of consumers. Therefore, the purpose of this study was mainly to identify and get insight into the main factors that mobile application consumer takes into consideration when purchasing mobile applications from the desktop iTunes App Store and the mobile App Store on the iOS devices: iPhone, iPad and iPod Touch. In this study both qualitative and quantitative case study approach was used. Accordingly twelve participants were selected from Stockholm and Uppsala area and their behaviour in the Apple’s App Store from the desktop iTunes and the mobile App Store on iOS devices was observed and recorded. Additionally questionnaires were administered to all participants in order to gather the necessary information. Consumers on the App Store behave differently depending on the unit they are using. This is because applications on the App Store are presented differently in the desktop iTunes App Store and the mobile App Store on the iOS devices. The study shows that young consumers with lower income purchase apps more frequently than the consumers with higher income. It also shows that consumers often consider the description, the screenshots, and the ratings when they are interested in buying applications. Furthermore consumers take a look more on ratings in the list on the iPhone and iPad App Store because the ratings are not shown in the list on the iTunes App Store. Similarly consumers tend to read the customer reviews more on the iTunes and iPad App Store as the customer reviews on the iPhone App Store is displayed in another page. Consumers were found to be more attracted by visual elements that they are already familiarized with, apps with famous logos and known fonts and styles but also to coherent and descriptive app names and strong colors (i.e. red, green, yellow, black and blue, respectively). The majority of the participants found the iTunes App Store messy and cumbersome to use. They preferred using the iPad App Store because they found it to be a good mixture of both iTunes and iPhone App Store but also because it has more options to consider. Although consumers behave differently depending on the unit they are using, the visual element of the apps, prior knowledge of consumers about the name of the apps, ratings, easy accessibility of screenshots and customer reviews of the apps were found to be the main factors to be considered by consumers when they visit app stores for purchase. Thus application developers and digital magazine publishers should consider these consumer behaviours in order to influence more downloads and successfully sell apps on the app stores.

As the increasing demand for high data-rate multimedia servicesin wireless broadband access, the advance wireless communication technologies have been developed rapidly. The Long-Term Evolution (LTE) is the new standard for wireless broadband access recently specified by the 3GPP(3rd Generation Partnership Project) on the way towards the fourth-generation mobile. In this thesis, we are interested in the 3GPP-LTE technology and focus on the turbo coding technique used therein. By employing MATLAB/Simulink, we build up the turbo codec simulation platform for 3GPP-LTE system. Two convolutional encoders that realize the concept of parallel concatenated convolutional codes (PCCCs) and a quadratic permutation polynomial (QPP) interleaver are used to implement the turbo encoder. The a posteriori probability (APP) decoder built-in Simulink is utilized to design the decoder that performs the soft-input and soft-output Viterbi Algorithm (SOVA). The zero-order hold block is used to control the number of decoding iteration for the iterative decoding process. We carry out the 3GPP-LTE turbo codec performance in the AWGN channel on the developed platform. Various cases that consider different data length, the number of decoding iteration, interleaver and decoding algorithm are simulated. The simulation results are compared to those of the Xilinx 3GPP-LTE turbo codec. The comparisons show that our turbo codec works properly and meets the LTE standard.

This thesis address the study of the recently popular Apple iOS platform, and its online application marketplace, called the ¡§App Store¡¨. The thesis examines the relation in Youtube videos and raking of the Apps. According to the research result, over 25% people use mobile device to watch the Apps videos. If marketer can manage the result of the searching and embedded the video in high traffic website, it can get more higher Apps ranking and Youtube video views. In addition, people/App player upload the video and share it with friends. It is just like the word and mouth marketing. Whenever people upload a lot of videos and get more video views, it can get higher App ranking. Furthermore, the video type is belonged to game trailer and walkthrough will has more views. In the other hand, the KUSO video will spread quickly in social network website and it brings more video views and Apps downloads potentially.

Compared with the advertisement on traditional media, mobile applications are totally different in usage situation, operating interfaces and communication modes with consumers. The study analyzes the influence of the positions (such as, pre-game advertisement and peripheral game advertisement) and formats (such as, dynamic banners advertisement and rich media advertisement) of advertisement on advertising effects. In addition, flow level is the modifying variable. The study collected a total of 220 effective samples by using judgmental sampling procedures to send out questionnaires over the Internet. Respondents must have experiences in playing Angry Bird on a smart phone The research results include: (1) The positions of advertisement influence significantly over the advertisement attitudes, brand and product memories; (2) The formats of advertisement influence significantly over the advertisement attitudes, and (3) The positions and formats of advertisement influence significantly over the advertisement attitudes when respondents are in low flow level. On the contrary, the positions and formats of advertisement influence significantly over brand and product memories when respondents are in high flow level.

Purpose: The research purpose is to assist hotel marketers in figuring out how to design an APP for hotel on the basis of current experience design situation and some suggestions will be proposed. Specifically, how strategies of experience design influence customers’ experiential value and how much the attributes of experience design influence customers’ experiential value will be examined, revealing which attributes of experience design are more important in generating customers’ experiential value. Particularly, with the development of mobile Internet and the increase of customers’ social needs, the communication among customers and providers will be strengthened. Therefore, this research will explore the importance of relational service design and social experience design in an APP context. Methodology: The experience design strategies, customer value dimensions and the theoretical framework are developed on the basis of literature. Questionnaire instrument is employed as a quantitative method in this research. At last, 244 questionnaires are recycled from APPs for hotel users in China. Findings: Firstly, the strategies of experience design，sensory experience design, functional service design, relational service design and social experience design, all have positive influence on customers’ corresponding experiential value. Secondly, in terms of attributes of experience design, the statistical findings indicate that appropriate layouts, online payment, online consultation and customer interaction show more influence on aesthetics, functional value, social-relational value and social-symbolic value respectively. Functional service design still plays an important role in current experience design, while relational service design, social experience design and sensory experience design will rise into importance. In terms of how to design an APP for hotel, a rank of strategies of experience design will be listed in the end, the well performed attributes of experience design will be kept in the design, while the attributes of experience design which are week in current situation will be improved. Theoretical Implications: Firstly, this paper brings “experience” to a context of an APP for hotel, which enriches the research about experiential marketing and experiential value, especially social value. Secondly, this paper proposes new experience design dimensions, sensory experience design, relational service design and social experience design, which explores a new design domain in the context of an APP for hotel. Practical Implications: This paper offers guidance for hotel marketers to implement experiential marketing by attributes of experience design, which in turn will bring more income and increase the competence of a hotel.

Alzheimer's disease (AD) is the leading cause of dementia. Amyloid plaques in the brain remain a pathological feature of AD. These plaques are primarily composed of amyloid β-protein (Aβ). It has been postulated that glycogen synthase kinase-3β (GSK3β) activity might exert a central role in the development of AD. GSK3β activity has been implicated in tau phosphorylation, APP processing, Aβ production and neurodegeneration. Quetiapine is frequently used to treat psychoses in AD patients at the late stage and has inhibitory effects on GSK3β activity in mouse brains after acute/subchronic treatment. Therefore, the proposed hypothesis is that chronic quetiapine administration after amyloid plaque onset reduces AD like pathology and alleviates AD like behaviours in APP/PS1 transgenic mice by inhibiting GSK3β activity. APP/PS1 transgenic mice were treated with quetiapine (2.5, 5 mg/kg/day) in drinking water starting from 3.5 months of age, for a period of 8 months. One week after behaviour testing, mice were sacrificed at 12 months of age. Half of the hemispheres were rapidly frozen for immunoblot and ELISA analyses and the other half were fixed with 4% paraformaldehyde for histological analyses. Quetiapine treatment reduced amyloid plaques formation in the cortex and hippocampus of AD mice. It also improved the behavioural deficits in these mice, including attenuating impaired memory and anxiety-like phenotypes. In addition, chronic quetiapine administration inhibited GSK3β, which resulted in reduced production of Aβ in cortices and hippocampi of transgenic mice. Quetiapine treatment also significantly decreased the activation of astrocytes and attenuated synapse integrity impairment in transgenic mice. These findings suggest that early application of quetiapine can alleviate memory deficits and pathological changes in the APP/PS1 transgenic mouse model of AD, and further support that modulation of GSK3β activity by quetiapine may be a therapeutic option for AD.