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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
221

BLEEM BLOOM: um ambiente para musicologia assistida por computador

Vieira de Araújo Junior, Dídimo 31 January 2011 (has links)
Made available in DSpace on 2014-06-12T16:00:35Z (GMT). No. of bitstreams: 2 arquivo6778_1.pdf: 5875026 bytes, checksum: dac41b089f0a27b12afcbe7bb0a420f0 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2011 / Tribunal de Justiça de Pernambuco / Pesquisas na área de análise musical são beneficiadas pela possibilidade de resolver questões que envolvem análises complexas de grandes quantidades de dados musicais com a utilização do computador. Diferentemente da maioria das pesquisas sobre expressividade musical - que se concentram em música clássica para piano - o projeto "Um País, Um Violão", realizado no Centro de Informática da Universidade Federal de Pernambuco, estuda a dimensão rítmica da bossa nova ao violão. Vários temas sobre aquisição de conhecimento a respeito da expressividade musical já foram trabalhados dentro do projeto como o reconhecimento de padrões rítmicos, análise harmônica, microrrítmo e microdinâmica. Em se tratando de pesquisa preliminar e pioneira, um dos problemas em torno do projeto é que seus trabalhos foram realizados sem foco no público-alvo, os pesquisadores em musicologia, o que implica deficiências na usabilidade, fazendo com que, em alguns casos, seja praticamente impossível sua utilização por um usuário sem conhecimentos avançados em computação. Um outro problema do projeto é que seus trabalhos foram implementados em momentos distintos, sem qualquer preocupação em como eles poderiam ser integrados, mantidos e expandidos. Este trabalho de dissertação objetiva resolver os problemas estruturais e de usabilidade relacionados. Para tanto, a abordagem utilizada envolve a aplicação de métodos de interação humano-computador - para conceber uma solução adequada ao público-alvo - e a análise dos trabalhos atuais, para o projeto e construção de uma nova arquitetura baseada em plugins. O objetivo é oferecer novas possibilidades de análise através da integração também dos resultados de cada trabalho, estimulando o uso prático dos trabalhos científicos realizados no projeto "Um País, Um Violão". As avaliações dos protótipos e experimentos, realizadas por colaboradores representantes do público-alvo, mostraram considerações positivas a respeito do software proposto
222

Uso da Taxonomia de BLOOM para modelagem de processo produtivo no setor de serviços voltado à prática no ensino a distância

Cardoso, Adão Marques dos Santos 23 December 2015 (has links)
Submitted by Napoleana Barros Martins (napoleana_martins@hotmail.com) on 2016-08-01T15:04:07Z No. of bitstreams: 1 Dissertação Adão Marques dos Santos Cardoso.pdf: 5573273 bytes, checksum: 8f40811743ab6e0dd181e74f98bd4c97 (MD5) / Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-26T13:19:46Z (GMT) No. of bitstreams: 1 Dissertação Adão Marques dos Santos Cardoso.pdf: 5573273 bytes, checksum: 8f40811743ab6e0dd181e74f98bd4c97 (MD5) / Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-26T13:22:36Z (GMT) No. of bitstreams: 1 Dissertação Adão Marques dos Santos Cardoso.pdf: 5573273 bytes, checksum: 8f40811743ab6e0dd181e74f98bd4c97 (MD5) / Made available in DSpace on 2016-08-26T13:22:36Z (GMT). No. of bitstreams: 1 Dissertação Adão Marques dos Santos Cardoso.pdf: 5573273 bytes, checksum: 8f40811743ab6e0dd181e74f98bd4c97 (MD5) Previous issue date: 2015-12-23 / Não informada / This study aims the creation of a practical activity of teaching model applicable to the Technical Course in Public Services of the Center of Technological Education of Amazonas (CETAM) in the distance education, held in twelve municipalities of Amazonas state, planned with the use of Bloom's Taxonomy, aiming to achieve the highest cognitive levels. Considering the regional characteristics, it was developed and implemented an educational activity focused on environmental context lived by the students, combining the concepts acquired in the virtual environment with the playfulness of a film; the development of an interdisciplinary project to generate a representative scenario of the knowledge acquired; project execution in a themed room format and ending with the presentation of an evaluation report. For this, the methodology used research was a study of qualitative and quantitative, the case study method, exploratory in nature, in which we analyzed the result of a planned activity to practice in distance education. It was used as a source, a structured survey questionnaire, with closed and open questions, based on the Likert scale and SERVQUAL, quantified and represented in tables and graphs. The data analysis was used for descriptive statistics, with absolute frequency calculation, relative and average, and inferential analysis. Therefore, this research emerges from the challenge of developing manufacturing activities from theory into practice in teaching distance mode. Thus aimed to analyze the results of a case, as regards its contribution to educational quality, improving learning course participants and therefore of their training. Bloom's Taxonomy gave objectivity to planning education, control of learning and assessing the performance of teacher students, thus enabling improvements in cognitive development. The teaching tools used in the movie and themed room have been evaluated by course participants as able to achieve the proposed objectives. The activity proved to be effective in contributing to the improvement of learning and the student's performance, encouraging self-learning and teamwork, as well as for vocational training of quality. / Este estudo objetiva a criação de um modelo de atividade prática de ensino aplicável ao Curso Técnico em Serviços Públicos do Centro de Educação Tecnológica do Amazonas (CETAM) na modalidade a distância (EaD), realizada em doze municípios do Estado do Amazonas, planejada com o uso da Taxonomia de Bloom, visando atingir os mais altos níveis cognitivos. Considerando as características regionais, foi elaborada e executada uma atividade de ensino com foco na contextualização do ambiente vivido pelos discentes, aliando os conceitos adquiridos no ambiente virtual com o lúdico de um filme. A elaboração de um projeto interdisciplinar para geração de um cenário representativo do conhecimento adquirido; a execução do projeto no formato de uma sala temática e finalizando com a apresentação de um relatório avaliativo. Para isso, a metodologia da pesquisa utilizada foi um estudo do tipo quali-quantitativo, pelo método de estudo de caso, de natureza exploratória, no qual analisa-se o resultado de uma atividade planejada para a prática no EaD. Foi utilizado como fonte, um questionário de pesquisa estruturado, com perguntas fechadas e abertas, baseado na escala Likert e SERVQUAL, quantificadas e representadas em tabelas e gráficos. A análise dos dados realizou-se por estatística descritiva, com cálculo de frequência absoluta, relativa e média, e por análise inferencial. Portanto, esta pesquisa emerge do desafio de desenvolver atividades transformadoras da teoria em prática na modalidade do ensino a distância. Assim, objetivou analisar os resultados de um caso concreto, no que concerne a sua contribuição para a qualidade educacional, a melhoria da aprendizagem dos cursistas e, consequentemente, de sua formação profissional. A Taxonomia de Bloom proporciou objetividade ao planejamento do ensino, ao controle da aprendizagem e a avaliação do desempenho dos cursistas, possibilitando assim melhorias no desenvolvimento cognitivo. As ferramentas didáticas utilizadas, o filme e a sala temática, foram avaliadas pelos cursistas como capazes de atingir os objetivos propostos. A atividade revelou-se eficiente na contribuição para a melhoria da aprendizagem e do desempenho do educando, estímulo a autoaprendizagem e ao trabalho em equipe, bem como para uma formação profissional com qualidade.
223

Os concursos vestibulares das universidades estaduais paulistas e o ensino de Química no nível médio / The entrance exam of University São Paulo state and the teaching of chemistry at the secondary level

Nicéa Quintino Amauro 17 September 2010 (has links)
A presente pesquisa teve como objetivo estudar a influência do sistema de verificação final de aprendizado sobre as práticas de ensino de Química no nível médio. Para tanto, identificamos e caracterizamos o nível de compreensão do conhecimento químico solicitado dos alunos egressos do ensino médio Brasileiro para seleção dos futuros universitários. Focamos nossas investigações sobre as questões das provas de Química da segunda fase dos concursos vestibulares da Universidade de São Paulo e da Universidade de Campinas, assim como nas provas de conhecimento específico para as carreiras das áreas de Ciências Biológicas e Ciências Exatas da Universidade Estadual Paulista e os relatórios de desempenho correspondentes, entre os anos de 1998 e 2008. O percurso metodológico desenvolvido analisa as questões em três eixos: (1) tema do ensino de química, que se utiliza da Proposta Curricular para o ensino de Química do estado de São Paulo de 1998; (2) processo cognitivo, que tem como referencia a Taxonomia de Bloom e (3) o desempenho médio dos candidatos nas questões das provas de Química. A triangulação dos dados evidenciou o caráter normativo, orientador e controlador destes exames sobre o sistema de ensino que os antecede. / This work aimed to study the influence of the system of final verification of learning on Chemistry teaching practices in high school. For that, we identified and characterized the level of chemical knowledge comprehension required from Brazilian students egress from high school for the selection of future undergraduates. We focused our investigations on the Chemistry questions of the second phase of the entrance tests from the University of São Paulo and the University of Campinas, as well as on the specific knowledge tests for careers in the field of Biological Sciences and Exact Sciences from the University of São Paulo State and the performance reports between the years of 1998 and 2008. Our methodological route follows the questions in three axes: (1) Chemistry teaching theme, which uses the Curriculum Proposition for the Chemistry teaching from the state of São Paulo from 1998; (2) cognitive process, whose reference is Bloom\'s Taxonomy and (3) average performance of the candidates in the questions in the Chemistry tests. The triangulation of data made clear the normative, guiding and controlling character of these exams on the teaching system that precedes them.
224

COMPORTAMENTO FENOLÓGICO E PRODUTIVO DAS CULTIVARES DE PESSEGUEIRO CHIMARRITA E GRANADA EM DIFERENTES PORTAENXERTOS NOS TRÊS PRIMEIRO ANOS DE IMPLANTAÇÃO / Phenology and agronomical behavior of peach cvs. Chimarrita and Granada on different rootstocks.

Rocha, Moacir da Silva 02 March 2006 (has links)
Made available in DSpace on 2014-08-20T14:22:04Z (GMT). No. of bitstreams: 1 tese_moacir_silva_rocha.pdf: 11149179 bytes, checksum: e3b2cd08e4d3981b82037c3e46190f2d (MD5) Previous issue date: 2006-03-02 / The peach crop in Brazil is spread from Rio Grande do Sul to Minas Gerais states. It has adapted to different environmental conditions, being cultivated in temperate and sub-tropical zones, since it develops in areas with latitudes between 30º S and 45º N. In Rio Grande do Sul, the regions that are outstanding on peach production are: Pelotas; Porto Alegre; and Serra Gaúcha. In the Serra Gaúcha besides peaches for fresh market, are also grown vine grapes and apples. In Porto Alegre, There are peach and plum productions supplying the local market. In Pelotas, most of the peaches produced are for the local industry. However, the canning peaches produced in Pelotas, has worsen the quality and lowered productivity in the last years due to the very variable winter temperature, low chilling hours and severe draught during summer and fall seasons. A way that may contribute for production regularity and to overcome damaging abiotic factors is the right choice of the rootstock. The objectives for this study were: a) to evaluate the agronomical behavior of cultivar Chimarrita on the rootstocks Aldrighi, Capdeboscq, GF305, Okinawa and Tsukuba 1; b) to evaluate the agronomical and phonological behavior of peach trees cultivar Granada on the rootstocks cvs. Aldrighi, Capdeboscq, and Okinawa, originated from both, seeds and air layering. It were observed that the trees of cultivar Chimarrita: on either rootstocks Capdeboscq or Okinawa had greater size and vigor; on Okinawa had higher fruit production, whereas on Capdeboscq had larger fruits, and delayed leaf fall, and had later bloom; the trees cultivar Granada independent of the rootstock cultivar had earlier fruit ripening as that on the same rootstock cultivars, originated from seeds (seedlings). Regarding to cultivar Granada, the trees on Capdeboscq seedling were of larger size, whereas those on Okinawa produced more fruits in the first bearing season. In general, the Granada trees on rootstocks originated from air layering had earlier harvesting, independent of the rootstock cultivar. / O pessegueiro é uma espécie cultivada desde o Rio Grande do Sul até o Estado sul da Bahia, adaptando-se às diferentes condições ambientais, sendo cultivada em zonas temperadas e subtropicais. Esta cultura se desenvolve em regiões com latitudes entre 32º S e 45º N. Dentre as regiões produtoras do Estado do Rio Grande do Sul têm-se destacado as regiões de Pelotas, Porto Alegre e da Serra gaúcha. Na região da Serra Gaúcha cultiva-se a videira principalmente para a industrialização de vinhos e derivados: a macieira destinada para o mercado interno e exportação e o pêssego mesa. Na grande Porto Alegre, a produção de pêssego de mesa e ameixa é destinada aos mercados locais. Na região de Pelotas, a mais de cinqüenta anos, a cultura do pessegueiro tem se direcionado à produção de pêssegos para atender a indústria regional. Pela falta de regularidade da temperatura e de chuvas nos últimos anos, principalmente no período que antecede a floração, entre o final do outono e início inverno, tem-se observado floração e brotação desuni forme, baixa qualidade das frutas e a baixa produtividade de pêssego na Região de Pelotas. Os programas de melhoramento genético do pessegueiro tem-se concentrado no desenvolvimento de variedades copa e deixado à questão do porta-enxerto a segundo plano. A escolha dos porta-enxerto pode contribuir para a regularidade da produção e para superação de fatores abióticos. Desta forma, o presente trabalho teve como objetivos: a) avaliar o desenvolvimento vegetativo, peso médio das frutas, eficiência produtiva, sólidos solúveis totais (SST), firmeza de polpa e coloração das frutas da cultivar Chimarrita enxertada nos porta-enxerto Aldrighi , Capdeboscq , GF305 , Okinawa e Tsukuba 1 ; b) avaliar a época da queda das folhas, época de brotação, período de floração, frutificação efetiva e período de colheita de pêssego da cultivar Chimarrita enxertada em cinco diferentes porta-enxerto; c) avaliar o desenvolvimento vegetativo da cultivar Granada enxertada em três diferentes porta-enxerto ( Adrighi , Capdeboscq e Okinawa ) obtidos por alporquia e por sementes; e d) avaliar a época de queda das folhas, início de brotação, período de floração, densidade floral, frutificação efetiva, início da colheita, intervalo de maturação e período de colheita das frutas da cultivar Granada enxertadas em três porta-enxerto obtidos por sementes e alporquia. Os resultados obtidos nos quatro experimentos permitem concluir que: a) o porta-enxerto Capdeboscq e Okinawa induziram maior desenvolvimento vegetativo na cultivar Chimarrita. O porta-enxerto Okinawa induziu maior rendimento produtivo na cultivar Chiamarrita, enquanto que Capdeboscq apresentou frutas de maior tamanho. (O porta-enxerto GF305 induziu o menor desenvolvimento vegetativo e mais baixa produtividade na cultivar e o porta-enxerto Tsukuba 1 proporcionou frutas de melhor coloração em Chimarrita nas condições em que foi instalado experimento b) Os porta-enxerto Capdeboscq e Okinawa prolongaram a permanência de folhas e o início de brotação mais tardia na cultivar Chimarrita. O porta-enxerto Okinawa retardou a plena floração e obteve a maior eficiência produtiva da cultivar Chimarrita no ano de 2005, enquanto que os porta-enxerto Aldrighi , GF305 e Okinawa anteciparam o iníncio da colheita das frutas da cultivar Chimarrita; c) O porta-enxerto Capdeboscq obtido de semente proporcionou maior crescimento vegetativo na cultivar Granada, enquanto que o Okinawa teve a maior produtividade no primeiro ano de colheita de pêssegos. Os porta-enxerto Capdeboscq e Okinawa apresentaram a melhor resposta no retardamento da queda das folhas; d) Os porta-enxerto obtidos por alporquia antecipou a colheita, com exceção de Aldrigui quando comparado aos obtidos de sementes. portaenxerto obtidos por alporquia mostrou melhor resposta na relação entre a floral e a frutificação efetiva em relação aos porta-enxerto de sementes.
225

Scaling Context-Sensitive Points-To Analysis

Nasre, Rupesh 02 1900 (has links) (PDF)
Pointer analysis is one of the key static analyses during compilation. The efficiency of several compiler optimizations and transformations depends directly on the scalability and precision of the underlying pointer analysis. Recent advances still lack an efficient and scalable context-sensitive inclusion-based pointer analysis. In this work, we propose four novel techniques to improve the scalability of context-sensitive points-to analysis for C/C++ programs. First, we develop an efficient way of storing the approximate points-to information using a multi-dimensional bloom filter (multibloom). By making use of fast hash functions and exploiting the spatial locality of the points-to information, our multibloom-based points-to analysis offers significant savings in both analysis time and memory requirement. Since the representation never resets any bit in the multibloom, no points-to information is ever lost; and the analysis is sound, though approximate. This allows a client to trade off a minimal amount of precision but gain huge savings(two orders less) in memory requirement. By making use of multiple random and independent hash functions, the algorithm also achieves high precision and runs, on an average,2×faster than Andersen’s points-to analysis. Using Mod/Ref analysis as a client, we illustrate that the precision is above 98% of that of Andersen’s analysis. Second, we devise a sound randomized algorithm that processes a group of constraints in a less precise but efficient manner and the remaining constraints in a more precise manner. By randomly choosing different groups of constraints across different runs, the analysis results in different points-to information, each of which is guaranteed to be sound. By joining the results of a few runs, the analysis obtains an approximation that is very close to the one obtained by the more precise analysis and still proves efficient in terms of the analysis time. We instantiate our technique to develop a randomized context-sensitive points-to analysis. By varying the level of randomization, a client of points-to analysis can trade off minimal precision (less than 5%) for large gain in efficiency(over 50% reduction in analysis time). We also develop an adaptive version of the randomized algorithm that carefully varies the randomization across different runs to achieve maximum benefit in terms of analysis time and precision without pre-setting the randomization percentage and the number of runs. Third, we transform the points-to analysis problem into finding a solution to a system of linear equations. By making novel use of prime factorization, we illustrate how to transform complex points-to constraints into a set of linear equations and transform the solution back as a points-to solution. We prove that our algorithm is sound and show that our technique is 1.8×faster than Andersen’s analysis for large benchmarks. Finally, we observe that the order in which points-to constraints are processed plays a vital role in the algorithm efficiency. We prove that finding an optimal ordering to compute the fixpoint solution is NP-Hard. We then propose a greedy heuristic based on the amount of points-to information computed by a constraint to prioritize the constraints. This results in a dynamic ordering of the constraint evaluation which, in turn, results in skewed evaluation of constraints where each constraint is evaluated repeatedly and different number of times in a single iteration. Our prioritized analysis achieves, on an average, an improvement of 33% over Andersen’s points-to analysis. We illustrate that our algorithms help in scaling the state-of-the-art pointer analyses. We also believe that the techniques developed would be useful for other program analyses and transformations.
226

FreeCore : un système d'indexation de résumés de document sur une Table de Hachage Distribuée (DHT) / FreeCore : an index system of summary of documents on an Distributed Hash Table (DHT)

Ngom, Bassirou 13 July 2018 (has links)
Cette thèse étudie la problématique de l’indexation et de la recherche dans les tables de hachage distribuées –Distributed Hash Table (DHT). Elle propose un système de stockage distribué des résumés de documents en se basant sur leur contenu. Concrètement, la thèse utilise les Filtre de Blooms (FBs) pour représenter les résumés de documents et propose une méthode efficace d’insertion et de récupération des documents représentés par des FBs dans un index distribué sur une DHT. Le stockage basé sur contenu présente un double avantage, il permet de regrouper les documents similaires afin de les retrouver plus rapidement et en même temps, il permet de retrouver les documents en faisant des recherches par mots-clés en utilisant un FB. Cependant, la résolution d’une requête par mots-clés représentée par un filtre de Bloom constitue une opération complexe, il faut un mécanisme de localisation des filtres de Bloom de la descendance qui représentent des documents stockés dans la DHT. Ainsi, la thèse propose dans un deuxième temps, deux index de filtres de Bloom distribués sur des DHTs. Le premier système d’index proposé combine les principes d’indexation basée sur contenu et de listes inversées et répond à la problématique liée à la grande quantité de données stockée au niveau des index basés sur contenu. En effet, avec l’utilisation des filtres de Bloom de grande longueur, notre solution permet de stocker les documents sur un plus grand nombre de serveurs et de les indexer en utilisant moins d’espace. Ensuite, la thèse propose un deuxième système d’index qui supporte efficacement le traitement des requêtes de sur-ensembles (des requêtes par mots-clés) en utilisant un arbre de préfixes. Cette dernière solution exploite la distribution des données et propose une fonction de répartition paramétrable permettant d’indexer les documents avec un arbre binaire équilibré. De cette manière, les documents sont répartis efficacement sur les serveurs d’indexation. En outre, la thèse propose dans la troisième solution, une méthode efficace de localisation des documents contenant un ensemble de mots-clés donnés. Comparé aux solutions de même catégorie, cette dernière solution permet d’effectuer des recherches de sur-ensembles en un moindre coût et constitue est une base solide pour la recherche de sur-ensembles sur les systèmes d’index construits au-dessus des DHTs. Enfin, la thèse propose le prototype d’un système pair-à-pair pour l’indexation de contenus et la recherche par mots-clés. Ce prototype, prêt à être déployé dans un environnement réel, est expérimenté dans l’environnement de simulation peersim qui a permis de mesurer les performances théoriques des algorithmes développés tout au long de la thèse. / This thesis examines the problem of indexing and searching in Distributed Hash Table (DHT). It provides a distributed system for storing document summaries based on their content. Concretely, the thesis uses Bloom filters (BF) to represent document summaries and proposes an efficient method for inserting and retrieving documents represented by BFs in an index distributed on a DHT. Content-based storage has a dual advantage. It allows to group similar documents together and to find and retrieve them more quickly at the same by using Bloom filters for keywords searches. However, processing a keyword query represented by a Bloom filter is a difficult operation and requires a mechanism to locate the Bloom filters that represent documents stored in the DHT. Thus, the thesis proposes in a second time, two Bloom filters indexes schemes distributed on DHT. The first proposed index system combines the principles of content-based indexing and inverted lists and addresses the issue of the large amount of data stored by content-based indexes. Indeed, by using Bloom filters with long length, this solution allows to store documents on a large number of servers and to index them using less space. Next, the thesis proposes a second index system that efficiently supports superset queries processing (keywords-queries) using a prefix tree. This solution exploits the distribution of the data and proposes a configurable distribution function that allow to index documents with a balanced binary tree. In this way, documents are distributed efficiently on indexing servers. In addition, the thesis proposes in the third solution, an efficient method for locating documents containing a set of keywords. Compared to solutions of the same category, the latter solution makes it possible to perform subset searches at a lower cost and can be considered as a solid foundation for supersets queries processing on over-dht index systems. Finally, the thesis proposes a prototype of a peer-to-peer system for indexing content and searching by keywords. This prototype, ready to be deployed in a real environment, is experimented with peersim that allowed to measure the theoretical performances of the algorithms developed throughout the thesis.
227

Taste and Odor Event Dynamics of a Midwestern Freshwater Reservoir

Howard, Chase Steven 11 1900 (has links)
Indiana University-Purdue University Indianapolis (IUPUI) / Eagle Creek Reservoir (ECR), located in the Midwestern U.S., is a freshwater limnic system plagued by seasonal Harmful Algal Blooms (HABs) which generate water-fouling Geosmin (GSM) and 2-Methylisoborneol (MIB) Taste and Odor (T&O) compounds. Past investigations of T&O event dynamics have identified Actinomycetes as responsible for MIB production and several genera of cyanobacteria for GSM production. During 2018, a temporally and spatially expansive sampling regimen of the reservoir was carried out and a battery of biological, chemical, physical, and hyperspectral experiments performed. The resulting data was analyzed using time series, cross-correlation, lag time, and multivariate analyses as well as machine learning algorithms to pick apart and interrogate any relationships between HABs, T&O events, and environmental parameters. The results show that local weather and watershed conditions exert significant control over the state of the reservoir and the behavior of the algal community. GSM and MIB peaked during early May under well-mixed, cold, and nutrient-rich water column conditions, then declined under summer thermal stratification before making a small resurgence during late season mixing. Bloom die-off and decay was effectively ruled out as a mechanism controlling T&O concentrations, and no links were found between T&O concentrations and algal biomass. Strong evidence was found that GSM/MIB concentrations were a response by bloom microbes to changing nutrient conditions within the reservoir, and it was determined that nutrient fluxes from the watershed 30-40 days prior to peak T&O concentrations are likely instrumental in the development of the slow- ix growing microbes characteristic of the reservoir. Attempts were made to assess spatial and temporal variability but no significant spatial differences were identified; differences between sampling sites were far smaller than differences between different sampling dates. The findings here add to the growing body of literature showing T&O and HAB dynamics are more closely linked to the relative abundance and speciation of nutrients than other parameters. Additionally, these findings carry important implications for the management of ECR and other similar freshwater reservoirs while highlighting the importance of reducing watershed eutrophication.
228

Removal of Microcystin-LR from Drinking Water Using Granular Activated Carbon

Villars, Kathryn E., Villars 12 December 2018 (has links)
No description available.
229

Effects of Low Bioavailable Nitrogen and Phosphorus on Cyanobacteria Dynamics in Eutrophic Lake Erie

Chaffin, Justin D. 11 July 2013 (has links)
No description available.
230

Type I Interferon Induction in Cutaneous DNA Damage Syndromes

Klein, Benjamin, Günther, Claudia 24 March 2023 (has links)
Type I interferons (IFNs) as part of the innate immune system have an outstanding importance as antiviral defense cytokines that stimulate innate and adaptive immune responses. Upon sensing of pattern recognition particles (PRPs) such as nucleic acids, IFN secretion is activated and induces the expression of interferon stimulated genes (ISGs). Uncontrolled constitutive activation of the type I IFN system can lead to autoinflammation and autoimmunity, which is observed in autoimmune disorders such as systemic lupus erythematodes and in monogenic interferonopathies. They are caused by mutations in genes which are involved in sensing or metabolism of intracellular nucleic acids and DNA repair. Many authors described mechanisms of type I IFN secretion upon increased DNA damage, including the formation of micronuclei, cytosolic chromatin fragments and destabilization of DNA binding proteins. Hereditary cutaneous DNA damage syndromes, which are caused by mutations in proteins of the DNA repair, share laboratory and clinical features also seen in autoimmune disorders and interferonopathies; hence a potential role of DNA-damage-induced type I IFN secretion seems likely. Here, we aim to summarize possible mechanisms of IFN induction in cutaneous DNA damage syndromes with defects in the DNA double-strand repair and nucleotide excision repair. We review recent publications referring to Ataxia teleangiectasia, Bloom syndrome, Rothmund–Thomson syndrome, Werner syndrome, Huriez syndrome, and Xeroderma pigmentosum. Furthermore, we aim to discuss the role of type I IFN in cancer and these syndromes.

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