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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Transtornos de humor na infância e adolescência: sintomas precoces em filhos de bipolares e traços de temperamento e caráter como endofenótipos na depressão maior / Mood Disorders in Children and Adolescents: Early Symptoms in Bipolar Offspring and Temperament and Character Traits as Endophenotypes for Major Depression

Zappitelli, Marcelo Cardoso [UNIFESP] 29 September 2010 (has links) (PDF)
Made available in DSpace on 2015-07-22T20:50:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-09-29 / Objetivo: Realização de dois estudos com crianças e adolescentes, visando identificar transtornos psiquiátricos em filhos de pais com transtorno bipolar tipo I, e avaliar traços de temperamento e caráter em pacientes com transtorno depressivo maior. Métodos: Estudo 1: O estudo envolveu uma série de casos composta por 35 crianças e adolescentes (20 meninos/15 meninas) de seis a 17 anos (média de idade: 12,5±2,9 anos). Todos os participantes foram avaliados através da entrevista diagnóstica The Schedule for Affective Disorders and Schizophrenia for School-Age Children – Present and Lifetime Version (K-SADS-PL). A história psiquiátrica familiar e os dados sociodemográficos também foram investigados. Estudo 2: Estudo caso-controle envolvendo 41 crianças e adolescentes (8–17 anos) com depressão maior pareadas por idade e sexo com 40 controles saudáveis. Todos os participantes foram avaliados pela entrevista diagnóstica K-SADS-PL. Os traços de temperamento e caráter foram avaliados através das versões para pais e para crianças do instrumento The Junior Temperament and Character Inventory (JTCI), e a gravidade da depressão através da escala Children’s Depression Rating Scale (CDRS). Resultados: Estudo 1: Pelo menos um diagnóstico psiquiátrico foi identificado em 71,4% da amostra. Altas taxas de transtornos específicos foram observadas: transtornos de humor (28,6%), transtornos disruptivos (incluindo transtorno de déficit de atenção e hiperatividade/TDAH) (40,0%) e transtornos de ansiedade (20,0%). A taxa de transtornos de humor comórbidos com TDAH (17,2%) foi maior do que a presença transtornos de humor isolados (11,4%). Psicopatologia foi frequentemente encontrada em parentes de segundo grau dos participantes (71,4%). Estudo 2: Os pacientes com depressão maior tiveram escores significativamente mais altos nas dimensões esquiva ao dano e busca por novidades, e escores mais baixos em dependência de gratificação, persistência, auto-direcionamento e cooperatividade em comparação aos controles saudáveis. A comorbidade com transtornos disruptivos influenciou praticamente todas as dimensões de temperamento e caráter, em geral aumentando as diferenças entre as médias de escores de casos e controles. Além disso, estar deprimido no momento da avaliação não influenciou os resultados, com exceção da dimensão dependência de gratificação de acordo com as informações fornecidas pelos pais. Conclusões: Filhos de bipolares constituem grupo de risco para desenvolver transtornos psiquiátricos, especialmente transtornos de humor e disruptivos. Crianças e adolescentes com transtorno depressivo maior têm um perfil de temperamento e caráter que difere de controles saudáveis, apontando para características estadoindependentes das dimensões esquiva ao dano e auto-direcionamento. / Purpose: To conduct two studies with children and adolescents, aiming to identify psychiatric disorders in the offspring of bipolar parents type I, and to evaluate temperament and character traits in patients with major depressive disorder (MDD). Methods: Study 1: The study involved a case series comprising 35 children and adolescents (20 males/15 females) aged 6 to 17 years (mean age: 12.5±2.9 years). All participants were assessed using the diagnostic interview The Schedule for Affective Disorders and Schizophrenia for School-Age Children – Present and Lifetime Version (K-SADS- PL). Psychiatric family history and demographics were also evaluated. Study 2: A case-control study comprising 41 MDD children and adolescents (8-17 years) matched by gender and age to 40 healthy controls (HC). All participants were diagnostically assessed with the K-SADS-PL. Temperament and character traits were measured by the parent and child versions of The Junior Temperament and Character Inventory (JTCI), and depression severity by The Children’s Depression Rating Scale - Revised (CDRS-R). Results: Study 1: At least one psychiatric disorder was identified in 71.4% of the sample. High rates of specific disorders were noted: mood disorders (28.6%), disruptive behaviour disorders (including attention deficit hyperactivity disorder/ADHD) (40.0%) and anxiety disorders (20.0%). The rate of mood disorders comorbid with disruptive behaviour disorders (17.2%) was higher than the rate of pure mood disorders (11.4%). Presence of psychopathology was commonly reported in second-degree relatives of the offspring (71.4%). Study 2: MDD subjects had significantly higher scores on harm avoidance and novelty seeking dimensions, and lower scores on reward dependence, persistence, self-directedness and cooperativeness compared with HC. Comorbidity with disruptive behaviour disorders exerted influence on almost all dimensions of temperament and character, in general increasing the mean score differences between MDD and HC subjects. Moreover, being currently depressed did not influence the results, except for reward dependence according to parent data. Conclusions: Bipolar offspring are at high risk for developing psychiatric disorders, especially mood and disruptive behaviour disorders. MDD children and adolescents have a different temperament and character profile compared to HC subjects, pointing towards trait-like characteristics of the dimensions harm avoidance and self-directedness. / TEDE / BV UNIFESP: Teses e dissertações
42

Autismo: discurso médico e discurso analítico / Autism: speech doctor and analytic discourse

Rêgo, Ana Paula Monteiro 15 March 2016 (has links)
This survey investigates the place of autism in the history of psychopathological disorders of childhood and stresses the autism situation in the current scenario, from the medical perspective and the from psychoanalysis perspective. In the last twenty years, the impact on the number of diagnostic of Disorder of Autism Spectrum (TEA) was increased by twenty times, these figures put the disorder in at epidemic condition, which explains the growing diversity of theories and therapeutic approaches about the disorder. This study is developed from a methodology of theoretical and qualitative research, carried out from the reading and rereading of the concepts and laws of medical science underlying the TEA, presented as medical discourse, and Lacanian psychoanalytic theories, which brought as speech analytical to understand autism. The theory of the discourse of Lacan (1969/1970) is used as the main reference of this research and Laurent assumptions (2012, 2013, 2014) based on the Lacanian foundations for understanding autism. The results of this study indicate that when autism is envisaged from the medical discourse, the psyche is reduced to the behavior and there is a concern with early diagnostic so that parents can train behaviors considered adaptive. The analytic discourse allows autistic symptoms are understood as psychic manifestations and an access road to the subject. On the one hand, this duplicity placements allows families seeking assistance to children diagnosed with ASD receive antagonistic guidelines and have difficulty understanding what is autism. On the other, the multiplicity of understanding about ASD ensures that unilateral positions do not meet the uniqueness of autism cases. Finally, our study allowed legitimize autism a plurality of understandings in a real battle. / Fundação de Amparo a Pesquisa do Estado de Alagoas / Esta pesquisa investiga o lugar do autismo na história dos transtornos psicopatológicos da infância e destaca a situação do autismo no cenário atual, a partir da perspectiva médica e da perspectiva da psicanálise. Nos últimos vinte anos, a incidência no número de diagnósticos de Transtorno do Espectro Autista (TEA) aumentou em vinte vezes, estes números colocam o transtorno dentro em condição epidêmica, o que justifica a crescente diversidade de teorias e abordagens terapêuticas acerca do transtorno. Este estudo foi desenvolvido a partir de uma metodologia de investigação teórico-qualitativa, realizada a partir da leitura e releitura dos conceitos e leis das ciências médicas que fundamentam o TEA, apresentada como o discurso médico, e das teorias psicanalíticas lacanianas, que trouxemos como discurso analítico para compreender o autismo. A teoria dos discursos de Lacan (1969/1970) foi utilizada como principal referencial desta investigação e os pressupostos de Laurent (2012, 2013, 2014) baseados nos fundamentos lacanianos para a compreensão do autismo. Os resultados deste estudo apontam que quando o autismo é perspectivado a partir do discurso médico, o psiquismo é reduzido ao comportamento e há uma preocupação com o diagnóstico precoce para que os pais possam treinar condutas consideradas adaptativas. O discurso analítico permite que os sintomas autísticos sejam compreendidos como manifestações psíquicas e uma via de acesso ao sujeito. Por um lado, esta duplicidade de posicionamentos possibilita que as famílias que buscam assistência para crianças com o diagnóstico de TEA recebam orientações antagônicas e tenham dificuldades em compreender o que é o autismo. Por outro, a multiplicidade de compreensão sobre o TEA garante que posicionamentos unilaterais não atendem a singularidade dos casos de autismo. Por fim, nosso estudo possibilitou legitimarmos o autismo numa pluralidade de compreensões, numa verdadeira batalha.
43

Medicina, educação e psiquiatria para a infância: o Pavilhão-Escola Bourneville no início do século XX / Medicine, education and psychiatry for infancy: the Pavilhão-Escola Bourneville at the beginning of the twenty century

Silva, Renata Prudêncio da January 2008 (has links)
Made available in DSpace on 2012-05-07T14:48:01Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 000036.pdf: 2897335 bytes, checksum: aa111da8f2c4cc28cc1a635eea541db1 (MD5) Previous issue date: 2008 / Esta dissertação tem como objetivo analisar a criação do Pavilhão-Escola Bourneville do Hospício Nacional de Alienados no início do século XX, primeira instituição brasileira para a assistência a crianças anormais. Descreve os diferentes personagens e idéias que estavam implicadas na criação deste Pavilhão. Com relação ao campo científico, destaca o conhecimento então produzido sobre os diagnósticos relativos à infância e sobre o método médico-pedagógico empregado no Pavilhão. Busca-se assim perceber as vias pelas quais a criança se constituiu em objeto não somente da ciência psiquiátrica, mas também das políticas públicas a ela relacionada naquele período. A pesquisa observa que a criação do Pavilhão-Escola Bourneville se insere num contexto mais amplo de constituição de uma assistência à infância vinculada aos ideais republicanos de construção de uma nação civilizada nos moldes europeus. Neste sentido, demonstra que o investimento da ciência e da assistência psiquiátrica no período em questão em relação à infância foi contemporâneo aos esforços no campo da medicina e educação, voltados para a construção de instituições e intervenções sociais que representavam a criança como o futuro da nação e, portanto, objeto privilegiado de atenção (AU)
44

Understanding and supporting positive parenting during homelessness

Bradley, Caroline January 2016 (has links)
This study aimed to develop and test the feasibility of a peer-led parenting intervention for parents living in London in temporary accommodation, seeking help with managing behavioural difficulties of a child (aged 2–11). A structured, group-based intervention (‘Empowering Parents, Empowering Communities- Temporary Accommodation’) was delivered by peer facilitators to N=15 parents across three group cohorts. Twelve parents (80%) completed the group programme at first attempt; one parent completed on their second attempt after re-joining in a different cohort. A mixed-method formative evaluation was used. The intervention’s feasibility was assessed in terms of attendance and completion rates (% parents completing ≥6 sessions); acceptability was assessed by satisfaction measure and qualitative participant interviews; and potential for impact was assessed by parent-reported standardised measures of child behaviour, parenting behaviour, parental wellbeing, parenting stress and social support. Reductions in child behavioural difficulties and improved parenting knowledge and practices were reported on standardised measures. Improved parental outcomes were described in qualitative interviews. Participants were highly satisfied with the intervention. The study concluded that peer-led parenting groups are feasible and potentially effective interventions for parents living in temporary accommodation. These findings warrant further testing under controlled conditions.
45

Die bydrae van die kinderpsigiatriese verpleegkundige tot primêre geestesgesondheid

Steyn, Erika 27 August 2014 (has links)
M.Cur. (Psychiatric Nursing) / In view of statistics available there is a definite need for a primary mental health service for children in the Republic of South Africa. Very little literature is available on the functions of the child psychiatric nurse, in this regard. This study was done to determine the functions of the child psychiatric nurse in the deliverance of a primary mental health care service for children. It was done by using the opinions of practicing child psychiatrists and child psychiatric nurses in South Africa.
46

Post-traumatic stress disorder in a group of sexually abused children

Westaway, Joan Lorraine 19 April 2017 (has links)
No description available.
47

The Relationship Between Childhood- And Adolescent-Onset Psychopathology And Adult Body Weight

Korczak, Daphne J. 10 1900 (has links)
<p>Current public health initiatives recognize that obesity is increasing to epidemic proportions in developed countries. In keeping with the view of obesity as a developmental, progressive condition, targeting childhood factors that predict increases in body mass index (BMI) may result in the development of more effective prevention interventions. To date, prospective studies of child-onset psychopathology and adult overweight in representative community samples are limited by short duration of follow-up into adulthood and an inability to make psychiatric diagnoses. Where available, childhood data has been analyzed together with adolescent data, such that it is difficult to disentangle the relationship between early psychological distress and adult overweight in these developmentally heterogeneous groups. The main objective of this thesis is to examine the relationship between childhood and adolescent symptoms of (i) Depression (ii) Attention Deficit Hyperactivity Disorder [ADHD] and (iii) Conduct Disorder [CD] with adult overweight, in a large, prospectively followed, community sample of Canadian children.</p> <p><strong> </strong>This thesis includes the 1,992 children aged 4-11 years and 1,302 adolescents aged 12-16 years who participated in the Ontario Child Health Survey (OCHS), a provincially funded, prospective cohort study of the psychiatric and general child health of a representative sample ofOntario community children undertaken in 1983 with follow-up assessment in 2000. Data are collected from multiple informants; psychiatric disorders are determined by a combination of parental, youth and teacher self-report and interviewer-administered measures. BMI is a derived variable determined from self-reported height and weight in 2000. Multiple regression analyses are undertaken to examine the association of child and adolescent mental illness with adult overweight, after controlling for the effects of age, sex, socioeconomic status, parental psychiatric history and, among the adolescent subgroup, cigarette smoking and alcohol use.</p> <p>Adults with a history of depression, ADHD or CD identified in childhood have increased body mass (BMI = 27.2 kg/m<sup>2</sup>, 27.7 kg/m<sup>2</sup>, and 27.9 kg/m<sup>2</sup>, respectively) compared to their nonaffected peers (BMI= 24.8 kg/m<sup>2</sup>). Children who experienced increased depressive symptoms (among boys) and CD symptoms (boys and girls) are at greater risk for future weight gain than children with fewer symptoms. Adolescent girls with Depression or Conduct Disorder are heavier in adulthood than their psychologically healthier peers. Although ADHD was initially found to be associated with adult overweight, this relationship is accounted for by the effect of conduct disturbance, regardless of child sex.</p> <p>This thesis suggests that psychopathology in childhood and adolescence predicts increased adult body mass in a large community sample ofOntarioyouth. In childhood, boys with depressive symptoms and boys and girls with disruptive behaviour are at particular risk. Among adolescents, girls with greater depressive symptoms or conduct disturbance are at increased risk of future weight gain. Research examining the trajectories of children with depressive and externalizing disorders is needed to understand the mechanism of the relationship between these disorders in childhood and eating behaviours in adulthood.</p> / Master of Science (MSc)
48

O contexto do diagnóstico da síndrome de Asperger.

Rocha, Simone Secco da 17 February 2012 (has links)
Made available in DSpace on 2016-01-26T12:51:39Z (GMT). No. of bitstreams: 1 simoneseccodarocha_dissert.pdf: 740139 bytes, checksum: cc3361e614f12885ebee89003ea2768c (MD5) Previous issue date: 2012-02-17 / Pervasive developmental disorders (PDDs) have symptomatic heterogeneity and a little known etiology, with the involvement of genetic and environmental factors. They are part of a group of &#64257;ve disorders, including Asperger syndrome (AS), which has the greatest diagnostic difficulty, because of the symptoms similar to other psychiatric conditions and also because of the lack of clarity with regard to diagnostic criteria included in the official classifications. This study evaluated the diagnostic context of AS. Forty-five individuals were investigated, 39 men and 06 women (6,5:1) with conclusive diagnosis of AS, confirmed by using a standard instrument. Parents or caretakers were interviewed according to a questionnaire designed by the author. On average, at the age of 3,3 symptomatic perception was observed by the parents (55%) but the first physical examination of children was only performed at the average age of 5,3.The time interval between symptomatic perception and conclusive diagnosis was 8,5 years, on average. The attention deficit disorder and hyperactivity (TDA/H-33,3%) was the most common diagnosis before obtaining a diagnosis of AS, in isolation or in combination with other diagnoses. The psychiatrist was responsible for the conclusive diagnosis in 77,8% of cases, on average, at the age of 11,8. The recommendations given by professionals who concluded the diagnosis of AS were: regular attendance to school (68,9%), considering seeing a psychologist (57,8%), making use of medicines (57,8%), considering seeing a speech-language pathologist (37,8%) and carrying out genetic evaluation (35,6%). The results revealed that: 1) symptoms of AS are usually noticed first by parents; 2) after considering the symptoms the first clinical examination of children is generally carried out at late age; 3) TDA/H in isolation or in combination with other diagnoses is the most frequent and mistakenly given to patients before the conclusion of AS, which is drawn late and is most frequently accomplished by a psychiatrist. In addition, the recommendations to instruct parents after the diagnosis of AS are unsatisfactory. Therefore, the diagnostic context of Asperger syndrome is complex and difficult, probably worsened by the lack of preparation of health professionals to detect the symptoms, aggravated by the lack of experts in the disorder or by the difficulties in the accessibility to specialized health professionals. / Os Transtornos Invasivos do Desenvolvimento (TID) têm heterogeneidade sintomática e etiologia pouco esclarecida, com envolvimento de fatores ambientais e genéticos. Compõem um grupo de cinco doenças, entre elas a Síndrome de Asperger (SA), a de maior dificuldade de diagnóstico, por compartilhar sintomas com outras afecções psiquiátricas e pela falta de clareza dos critérios diagnósticos contidos nas classificações oficiais. Este estudo avaliou o contexto do diagnóstico da SA. Foram investigados 45 indivíduos, 39 homens e seis mulheres (6,5:1), com diagnóstico conclusivo de SA, confirmado com a utilização de um instrumento padronizado. Os responsáveis foram submetidos a uma entrevista de acordo com um questionário construído pela autora. Em média, aos 3,3 anos houve a percepção sintomática por parte dos pais (55%) mas, apenas aos 5,3 anos em média, a criança realizou a primeira avaliação clínica. O tempo entre a percepção sintomática e o diagnóstico conclusivo foi, em média, de 8,5 anos. O diagnóstico mais frequente antes do de SA, foi de Transtorno do Déficit da Atenção e Hiperatividade (TDAH-33,3%), isolado ou combinado com outros diagnósticos. O psiquiatra foi o responsável pelo diagnóstico conclusivo em 77,8% dos casos, em média, na idade de 11,8 anos. As orientações oferecidas pelos profissionais que concluíram o diagnóstico de SA foram: frequentar escola regular (68,9%), procurar um psicólogo (57,8%), fazer uso de medicamentos (57,8%), procurar um fonoaudiólogo (37,8%) e realizar avaliação genética (35,6%). Os resultados mostraram que os sintomas da SA são primeiramente mais percebidos pelos pais, que a idade da primeira avaliação clínica relacionada aos sintomas geralmente é tardia, que o TDAH isolado ou combinado com outros diagnósticos, é o mais frequente e erroneamente recebido pelos pacientes antes da conclusão de SA, que é feita tardiamente, e na maior parte dos casos por um psiquiatra. Além disso, as orientações dadas às famílias após o diagnóstico de SA são insuficientes. Portanto, o contexto do diagnóstico de Síndrome de Asperger é complexo, difícil, possivelmente agravado pela falta de preparo dos profissionais da saúde em reconhecer os sintomas, falta de especialistas na doença ou pela dificuldade de acesso aos profissionais especializados.
49

När kunskapen inte räcker till : En kvalitativ studie av barnpsykiatrins uppfattning om användandet av sociala medier hos barn med psykisk ohälsa / Insufficient knowledge : A qualitative study of how child psychiatry experiencesthe usage of social media when they encounter children with mental illness

Björklin Wolff, Emilia, Jonsson, Jenny January 2019 (has links)
Sociala medier är idag en självklar del i många barns vardag och forskning har visat en kraftig ökning av användandet under de senaste åren. Samtidigt har forskning visat att psykisk ohälsa hos barn blivit vanligare och vart tionde barn i Sverige lider av psykisk ohälsa. Utifrån detta var studiens syfte att undersöka hur professionella inom barnpsykiatrin uppfattar användandet av sociala medier vid mötet med barn. Fyra kvalitativa intervjuer med kuratorer i olika verksamheter inom barnpsykiatri har genomförts. Resultatet visade att kuratorernas upplevelser av sociala medier är att det inverkar på barns mående och att det finns en kunskapsbrist kring sociala medier. Resultatet visade även att det saknas metoder och material för att kartlägga och hantera användandet av sociala medier hos barn med ångestproblematik. Studien visade därmed att det finns ett behov inom barnpsykiatrin att utveckla arbetet med sociala medier. / Today social media is a natural part of many children's everyday life and research has shown a vigorous increase of the usage. At the same time research has shown that mental illness among children has become more frequent and every tenth child suffers from a mental illness. Due to this, the aim of this study was to look into how professionals within child psychiatry experience the usage of social media when they encounter children. Four interviews with curators within child psychiatry was conducted. The results showed that curator’s experiences of social media are that they have an impact on children's mental health and that there is a lack of knowledge about social media in child psychiatry. There is also a lack of methods to map and manage the usage of social media among children.
50

Caracterização de crianças e adolescentes em risco para o desenvolvimento de transtorno obsessivo-compulsivo / Characterization of children and adolescents at risk for the development of obsessive-compulsive disorder

Neder, Priscila Chacon 06 May 2015 (has links)
Objetivos. Esta tese vai ao encontro da proposta da psiquiatria do desenvolvimento, investigando sintomas clínicos, fatores de risco e potenciais endofenótipos que possam colaborar com diagnósticos precoces e o desenvolvimento de estratégias de prevenção. Métodos. O primeiro estudo relata a investigação e caracterização de uma amostra de crianças e adolescentes em risco para o desenvolvimento do transtorno obsessivocompulsivo (TOC). Para este propósito, 66 crianças e adolescentes com um familiar de primeiro grau com diagnóstico de TOC tiveram seus dados analisados de acordo com a presença ou ausência de sintomas obsessivocompulsivos. O segundo estudo consistiu no desenvolvimento e testagem de um paradigma dot probe de viés atencional relacionado a sintomas do TOC e na sua investigação enquanto possível endofenótipo do transtorno. Para tanto, três grupos de crianças foram selecionados: crianças com diagnóstico de TOC, em alto risco para o desenvolvimento de TOC (com presença de sintomas obsessivo-compulsivos e história familiar de primeiro grau de TOC) e crianças controle. O paradigma incluiu pares de estímulos aversivos (ativos) e neutros das dimensões de sintomas de contaminação/limpeza e simetria apresentados em 500 ms e 1250 ms. Resultados. O primeiro estudo obteve três resultados importantes. Primeiro, a amostra de crianças com familiar de primeiro grau com TOC apresentou elevada prevalência de sintomas obsessivo-compulsivos, confirmando a familiadade do transtorno. Segundo, crianças com e sem sintomas obsessivo-compulsivos apresentam prevalências diferentes de comportamento coercivo relacionados ou não aos sintomas obsessivo-compulsivos. Terceiro, familiares de crianças com sintomas obsessivo-compulsivos apresentaram mais frequentemente a dimensão de sintomas de contaminação/limpeza do que familiares de primeiro grau de crianças sem sintomas obsessivo-compulsivo. O segundo estudo teve como principais resultados: 1) crianças com TOC apresentam índices mais altos de desconforto pelos estímulos ativos comparados aos dos outros dois grupos de crianças, indicando que o paradigma é eficiente na sua avaliação; 2) a avaliação dos estímulos ativos da dimensão de contaminação/limpeza está associada à presença de seus respectivos sintomas no sujeito; 3) o grupo de crianças com TOC apresentou viés atencional na direção do estímulo aversivo em todas as quatro condições do paradigma (contaminação/limpeza e simetria com 500ms e 1250ms); 4) crianças com TOC apresentaram viés atencional maior do que crianças em risco para o desenvolvimento de TOC e controles sucessivamente, sempre na direção do estímulo aversivo exceto, no paradigma de simetria de 500ms; 5) O viés atencional na direção do estímulo ativo de contaminação no paradigma de 1250ms está associado à presença da dimensão de sintomas de contaminação. Conclusões. Os achados aqui descritos reforçam a familialidade do TOC, contribuem com achados de características associadas ao transtorno na infância e adolescência, reforçam a presença de um marcador de risco importante para o desenvolvimento de estratégias de detecção e prevenção precoces. Os resultados encontrados têm importantes implicações para a melhora do conhecimento de fatores de risco para o desenvolvimento do TOC e características associadas, que devem ser considerados em contextos clínicos e de pesquisa / Objective. This thesis goes in line with the concept of developmental psychiatry investigating clinical symptoms and risk factors that can further provide earlier diagnoses and preventive interventions. Methods. The first study reports the investigation and characterization of a sample of children and adolescents at risk for the development of obsessive compulsive disorder (OCD). For this purpose, 66 children and siblings with a first degree relative diagnosed with OCD had their clinical data analyzed according to the presence of obsessive compulsive symptoms. The second study consisted on the development and testing of an attentional bias dot probe paradigm with OCD relevant content to evaluate pediatric patients with OCD and further investigate it as a possible phenotype of OCD. For this purpose three groups of children were selected: 1) children with OCD; 2) children at risk for OCD (presenting obsessive compulsive symptoms and with a first degree relative diagnosed with OCD); 3) control group (children with none of the Axis I Psychiatric diagnoses). The paradigm included pairs of aversive (active) and neutral stimulus of contamination/cleaning and symmetry symptom dimensions and had two different time presentations of the stimulus, 500 and 1250 milliseconds. Results. The first study had with tree main findings. First, our sample of children with a first degree affected with OCD had a very high prevalence of obsessive-compulsive symptoms, confirming the familiality of the disorder. Second, children with and without obsessive-compulsive symptoms presented different rates of coercive behaviours, that can be related or not to obsessive-compulsive symptoms. Third, first degree relatives of children who had obsessive compulsive symptoms had significantly more contamination/cleaning dimension of obsessive compulsive symptoms than relatives of children without obsessive compulsive symptoms. The second study had the following main findings: 1) children with OCD had higher rates of discomfort caused by active stimulus than the other two groups of children, indicating that the paradigm is efficient for its purpose; 2) the evaluation of active stimulus of the contamination/cleaning dimension is associated to the presence of its respective symptoms; 3) the group of children with OCD had attentional bias towards the active stimulus in all four conditions of the paradigm (cleaning/contamination and symmetry in 500ms and 1250ms); 4) children with OCD had higher attention bias than children at risk and controls always towards the active stimulus with the exception of the 500 ms symmetry paradigm; 5) the attentional bias towards the active stimulus in the 1250 ms contamination paradigm is associated to the presence of symptoms of the contaminations dimension. Conclusions. The results reinforce the familiality of OCD, contributing with findings of associated characteristics to the disorder in childhood and adolescence and reinforcing the presence of an important risk marker for the development of strategies of early detection and prevention. The results have important implications to the improvement of the knowledge of OCD and associated characteristics, which should be considered in clinical and research contexts

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