Introdução: A definição do volume-alvo macroscópico, principalmente referente a casos de câncer de pulmão, exige o maior número de informações possíveis no que diz respeito à localização, extensão e mobilidade tumoral. A literatura demonstra um importante avanço quando utilizada imagens metabólicas como é o caso da tomografia por emissão de pósitron/tomografia computadorizada (PET/CT), porém a sua aplicação nos planejamentos radioterápicos ainda é muito discutida devido ao seu grau de complexidade. Objetivos: Avaliar o impacto da PET/CT no delineamento tumoral em casos de câncer de pulmão não-pequenas células (CPNPC) e linfonodos regionais. Materiais e Métodos: Foram selecionados retrospectivamente estudos de PET/CT de 26 casos de câncer de pulmão. Todos foram confirmados por biópsia, sendo em sua totalidade CPNPC. Todos os estudos foram realizados em um equipamento de PET/CT dedicado com parâmetros de aquisição idênticos. A interpretação das imagens e posterior delineamento foram realizados por dois médicos experientes, um radioterapeuta e um nuclear/radiologista. Os parâmetros ótimos de visualização foram pré-definidos, sendo mandatórios para os delineamentos. Os delineamentos foram realizados em duas etapas principais. A primeira relacionada ao desenho tumoral somente pela CT e a segunda, após no mínimo duas semanas de descanso visual, referindo-se ao desenho tumoral pela PET/CT. Somente o volume tumoral macroscópico (GTV) e os linfonodos regionais aumentados ou PET positivos foram delineados. Índices de conformidades (IC) foram calculados, tanto interobservadores (11 casos), quanto intra-observador (26 casos). Para a comparação entre observadores e entre delineamentos em relação ao volume, foi considerado o teste não-paramétrico de Wilcoxon. As comparações em relação ao IC foram feitas usando-se o teste t de Student para amostras pareadas. Em todos os testes, valores de p <0,05 indicaram significância estatística. Os dados foram analisados com o programa computacional SPSS® Statistics 17.0 (EUA). Resultados: A análise dos dados demonstrou diferença significativa entre os volumes médios delineados na CT e na PET/CT (p = 0,02), com evidente redução volumétrica no delineamnto por PET/CT. Houve diferença significativa entre os volumes CT delineados pelos dois observadores (p = 0,03) e uma tendência a apresentar diferença significativa entre volumes PET/CT (p = 0,05). A avaliação volumétrica intraobservador foi significativa (p < 0,01) apenas para o médico nuclear/radiologista, com redução de até 51% do volume CT e uma relação entre modalidades de 2,11 ± 0,22. Na análise dos IC, não houveram diferenças significativas entre as duas modalidades de imagem (p = 0,598). A análise dos IC intra-observadores demonstrou que para o radioterapeuta a PET/CT apresenta um impacto de 46% (IC médio = 0,54 ± 0,06), já para o nuclear/radiologista, o impacto foi de 65% (IC médio = 0,35 ± 0,06), representando uma diferença significativa (p = 0,03) em relação ao IC entre o médicos observadores. Para a análise linfonodal a PET/CT apresentou importante diferença na visualização de linfonodos, alterando 10 dos 26 casos, sendo 9 para a positividade apenas na fusão. Conclusão: A PET/CT apresentou significativo impacto no desenho do GTV e linfonodos regionais para casos de CPNPC. / Introduction: The definition of gross target volume, especially concerning cases of lung cancer, requires the greatest amount of information possible with regard to location, tumor size and tumor mobility. The literature demonstrates an important advancement using metabolic images such as PET/CT, however, its application in radiotherapy planning is still controversial due to its complexity. Objectives: To assess the impact of PET/CT in tumor delineation in cases of non-small cell lung cancer and regional lymph nodes as additional findings. Materials and Methods: Retrospectively studies of PET/CT of 26 lung cancer cases were selected. All were confirmed by biopsy, in its entirety NSCLC. All studies were performed on a PET/CT with dedicated acquisition identical parameters. Image interpretation and subsequent delineation were performed by two experienced physicians, one radiotherapist and the another nuclear/radiologist. The optimal parameters display were pre-defined, being mandatory for the designs. Each case received an identification of three random letters to access the medical images to be analyzed. The delineation was made in two main steps. The first reference to the drawing only in tumor CT and the second, after two weeks of visual rest, referring to the drawing on tumor PET/CT. Only the gross tumor volume (GTV) and regional lymph nodes were enlarged or PET + outlined. Conformity index (CI) were calculated both interobserver (11 cases), and intra-observer (26 cases). For comparison between observers and between designs in relation to the volume, was considered the nonparametric Wilcoxon test. Comparisons regarding the conformity index were made using the Student t test for paired samples. To assess the degree of agreement regarding positive lymph nodes were estimated with kappa coefficients of agreement. In all tests, p values <0.05 were considered statistically significant. Data were analyzed with the software SPSS Statistics 17.0 (USA). Results: Data analysis showed significant difference between the average volumes delineated on CT and PET/CT (p = 0.02), with obvious volume reduction. Significant difference between the volumes delineated by CT observars medical distinct classes (p = 0.03) and a tendency to present significant difference between volumes PET / CT (p = 0.05). The intraobserver volumetric evaluation was significant (p <0.001) only for observer 2, being the nuclear medicine physician / radiologist, reducing up to 51% of the volume CT and a relationship between methods of 2.11 ± 0.22. In the analysis of CI, there were no significant differences between the two imaging modalities (p = 0.598).CI analysis showed that intra-observer to observer 1 PET / CT has an impact of 46% (average CI = 0.54 ± 0.06). The viewer 2, the impact was greater, 46% (average IC = 0.39 ± 0.03), representing a difference of opinion regarding the CI (p = 0.03) between the medical classes. To regional lymph nodes with PET/CT revealed an important difference in the visualization of lymph nodes, changing 10 of the 26 cases, 9 to positivity only in the image fusion.Conclusion: PET/CT has a significant impact on the design of the GTV and regional lymph nodes in cases of NSCLC.

Denna studie har som mål att undersöka hur normer och konformitet skapas i ett modernt, teknologiskt samhälle genom att studera satirisk populärkultur. Det är den tredje säsongen av den satiriska, dystopiska tv-serien Black Mirror som studeras. Syftet är att hitta avsnittens gemensamma diskurser kring normer för att därefter göra en koppling till den teknologiska utvecklingen och dagens samhälle. Studiens grundläggande teori och metod är multimodal kritisk diskursanalys (MCDA) som analyserar både skrivna, verbala och visuella tecken. Det teoretiska ramverket består även av socialpsykologisk rollteori, ideologiteori och teknologisk determinism, som används för att hitta och analysera materialets diskursiva teman. Tre teman med fokus på normer upptäcks - rädslan för utanförskap och nonkonformism, politisk ideologi som normskapare samt teknologins påverkan på normer. Trots att seriens avsnitt huvudsakligen utspelar sig i en dystopisk och högteknologisk framtid, är det möjligt att genom tematiseringen observera flera intressanta kopplingar till dagens samhälle. I analysen hittas samband till bland annat förintelsen, Sverigedemokraterna, fenomenet #metoo och Kim Kardashians populära Instagram-konto. / The intention of this study is to explore how norms and conformity is created in a modern, technological society, through studying satirical popular culture. The third season of the satirical, dystopic tv-series Black Mirror, is the subject of analysis. The aim is to find the episodes shared discourses evolving norms, to then draw parallells to technological development and todays society. The underlying theory and method is the multimodal critical discourse anlaysis (MCDA), for an analyzis of written, verbal and visual elements. The teoretical framwork additionally consists of social psycology’s roletheory, ideology theory and techological determinism, which will be used to find and analyze the materials discoursive themes. Three themes with focus on norms are discovered - fear of exclusion and nonconformity, political ideology as a creator of norms and technology’s influence on norms. Although the episodes mainly take place in a dystopic, highly technological future, it is possible through thematisation to observe connections to todays society. Although the series mainly takes palce in a dystopic and highly technological future, it is possible through thematization to observe several interesting parallells to todays society. In the analysis connections are found including The Holocaust, Sverigedemokraterna, the #metoo-fenomenon and Kim Kardashians popular Instagram-account.

La thèse examine la comparaison des effets du contrat d’entreprise en droit français et en droit vietnamien. Au sein des contrats spéciaux, dans un monde d’économie de services accrue, le contrat d’entreprise joue désormais un rôle majeur. Ses multiples facettes pourraient d’emblée permettre de dresser une liste de métiers. Elle serait haute en couleur, puisque la plupart des prestations de services peuvent se couler dans le moule juridique du contrat d’entreprise, pour le quel se trouvent concernés artisans,artistes, professions libérales, etc. Synallagmatique, le contrat d’entreprise engendre des obligations réciproques à la charge de l’entrepreneur et du maître de l’ouvrage. Elle a permis de mettre en évidence les obligations qui constituent le droit commun du louage d’ouvrage, et de s’apercevoir que les obligations nées du contrat d’entreprise ainsi que ses effets revêtent des contours spécifiques qui s’expliquent par particularités de la convention. Ces particularités sont indéniables s’agissant des obligations principales et accessoires de l’entrepreneur à l’égard du maître de l’ouvrage et à l’inverse. Ces deux parties devraient être sanctionnées pour l’inexécution des obligations contractuelles et être exonérées de la responsabilité en justifiant les causes d’exonération. L’étude comparative de ces particularités en droit français et en droit vietnamien permettra de constater les similitudes et les divergences entre les deux systèmes juridiques. Les deux pays sont proches sur le plan juridique. Ainsi, la conclusion qui s’en dégage est que certaines dispositions du droit français pourraient utilement inspirer les législateurs vietnamiens et vice versa. / The thesis examines the comparison of the effects of the contract of enterprise in Vietnamese law and French law. Within the special contracts, in a world of greater economy of services, the contract of enterprise plays from now on a major role with various operations. It would be with a ruddy complexion, because most of the services can steal into the legal mold of the contract of enterprise, thus that are concerned craftsmen, artists, medical services, liberal professions, etc. Synallagmatic, the contract of enterprise engenders mutual obligations chargeable to the contractor and the owner. The study allowed to point out the obligations that constitute the common rules of the contract of enterprise and, to notice that the obligations following the contract of enterprise are specific because of the particular aspects of this agreement.The particularities are undeniable with respect to the main and secondary obligations of the contractor towards his owner and on the contrary. Both parties should be sanctioned by the non-fulfillment of the contractual obligations and to be exempted from the responsibility by justifying the causes of exemption. Comparative studies of these particularities in French law and in Vietnamese law will allow to notice the similarities and the differences between both legal systems. The two countries are close on the legal plan. Thus, the conclusion that emerges is that certain provisions of the French law could usefully inspire the Vietnamese legislators and vice versa

Apprendre une nouvelle langue signifie exploiter, plus ou moins consciemment,l’espace de la proximité du système linguistique cible avec d’autres langues. Cette proximité encourage les transferts entre les systèmes linguistiques, qui acquièrent une valeur positive ou négative à l’intérieur de l’interlangue vue comme le troisième système linguistique développé par l’apprenant, différent de la langue source et de la langue cible. Nous nous intéressons à ces transferts et à l’influence que ceux-ci exercent sur l’interlangue, dans le cas des apprenants roumains de FLE, étudiant aussi l’italien et l’espagnol. L’analyse des données nous permet de rendre compte du rapport qui s’établit entre la conformité avec la norme et la complexité de l’interlangue et aussi de déterminer le rôle des transferts linguistiques positifs et négatifs par rapport à ces deux dimensions de l’interlangue (la complexité et la conformité) / Learning a new language means making use, more or less consciously, of the sphere ofproximity between the target linguistic system and the other languages. This proximitystimulates some transfers between the linguistic systems, thus acquiring either a positive or anegative value within interlanguage. This one is considered the third language system developedby the learner, being different from the source language and the target language. We focus onthese transfers and on their influence over interlanguage, in the case of the Romanian learnersstudying French as a foreign language, but also Italian and Spanish.The data analysis enables us, on the one hand, to give an account of the connectionexisting between the conformity to the norm and the complexity of interlanguage and, on theother hand, to ascertain the role of both positive and negative linguistic transfers against thesetwo dimensions of interlanguage (the complexity and the conformity) / A învăţa o nouă limbă înseamnă a exploata, în mod mai mult sau mai puţin conştient,spaţiul proximităţii sistemului lingvistic ţintă cu alte limbi. Această proximitate încurajeazătransferurile între sistemele lingvistice, care capătă o valoare pozitivă sau negativă în interiorulunei interlangue vazută ca fiind al treilea sistem lingvistic dezvoltat de un elev, diferit de limbasursă şi de limba ţintă. Suntem interesaţi de analiza acestor transferuri şi de influenţa pe careacestea o exercită asupra acestei interlangue, în cazul elevilor români care studiază FLE şiitaliana sau spanilola.Analiza datelor ne permite să explicăm raportul care se stabileşte între conformitatea cunorma şi complexitatea limbii elevului şi să determinăm rolul transferurilor lingvistice pozitive şinegative în raport cu aceste două dimensiuni ale unei interlangue (complexitatea şiconformitatea)

Les sciences relevant des sciences du vivant et de l'environnement (biologie, risques naturels, télédétection, etc.) ont depuis de nombreuses années accumulé les données d'observation et développé de grandes variétés de traitements.Les scientifiques de ces domaines doivent asseoir leur réflexion par des validations expérimentales. Celles-ci nécessitent la mise en œuvre de chaînes de traitements (ou protocoles expérimentaux) plus ou moins complexes.Le concept de "workflow" a été introduit de manière globale et raffiné en "workflow scientifique".Les systèmes actuels restent cependant difficiles à appréhender par des scientifiques dont les préoccupations ne relèvent pas directement de l'ingénierie informatique.L'approche suivie, en terme de méthodologie et de composants, propose une solution à ce problème.L'hypothèse initiale repose sur la vision utilisateur qui conçoit son travail en trois étapes :- La phase de planification, qui consiste à définir un modèle métier abstrait d'un workflow ;- La phase intermédiaire, qui consiste à concrétiser le modèle abstrait précédemment défini, en localisant les diverses ressources existantes au sein de ce que nous désignons comme contexte de travail. La définition, la vérification et la validation des modèles concrets reposent sur la connaissance des experts et sur la compatibilité des éléments du modèles ;- La phase dynamique, qui consiste à exécuter le modèle concret validé avec un moteur d'exécution.La thèse se focalise principalement sur les divers problèmes soulevés dans les deux premières phases (planification et intermédiaire).A partir d'une analyse des travaux existants, nous déclinons les divers maillons :méta modèle et langage de workflow, contexte de travail, graphe de ressources, traitement de cas d'incompatibilité de la proposition.La validation des travaux s'est effectuée dans plusieurs domaines cibles: biologie, risques naturels et télédétection.Un prototype a été développé, il propose les fonctionnalités suivantes :conception et sauvegarde de chaines de traitements abstraites,description et localisation de ressources, vérification de la validité des chaînes concrètes. / For many years in life and the environmental science domains (such asbiology, risk, remote sensing, etc.), observational data haveaccumulated and a great number of related applications have beenimplemented. Scientists working in these domains have to establish theirreflections and evaluations based on experimental validations, whichrequire a more or less complex workflow. The "workflow" has beenintroduced as a global and general concept, and defined as "scientificworkflow". However, the current complex systems remain difficult toaccess by scientist, whose expertise is not directly related to thedomain of computer science engineering.Within the following approach we propose a methodical solution for thisproblem.The initial hypothesis is based on the vision of an user, who conceiveshis work in three stages:1) The conception stage, which consists of constructing an abstractworkflow model;2) The intermediate stage, which represents an instantiation step of thepre-defined abstract model, by locating different existing resources inan environment, named "work context" in our approach. The definition,verification and validation of a concrete model depend on the experts'knowledge of his specialized domain and the compatibility of elements inthe model.3) The dynamic stage, which consists of establishing and executing thevalid concrete model by using a workflow execution engine.In this thesis we mainly concentrate on the different problems raised bythe first two stages (conception and intermediate). Based on an analysisof existing efforts we decline some elements such as meta model and theassociated workflow language, work context, resource graph, solution propositions for incompatible compositions.The validation for our approach has been carried out in various target domains such as biology, natural risk and remote sensing. A prototype has been developed, which provides the following functionalities:construction and saving the abstract workflow models, description and location of (data / application) resource, verification and validation of concrete workflow models.

[pt] O objetivo da dissertação é analisar em que medida a avaliação da conformidade de projetos de engenharia de grandes empreendimentos, conduzidos segundo regime epecista, pode ser utilizada como ferramenta de aprendizagem organizacional pelas entidades envolvidas. No contexto organizacional em que a pesquisa se insere, os objetos de análise são os projetos de três terminais aquaviários a serem operados pela Transpetro: (i) Pecém – Tecem (CE); (ii) Barra do Riacho (ES); e (iii) Ilha Comprida (RJ) e a unidade principal é a Unidade de Implementação de Empreendimentos para Transpetro (IETR) da Petrobras. A metodologia compreende: (i) pesquisa bibliográfica e documental sobre os temas centrais; (ii) seleção do tipo de caso e delimitação das unidades de caso; (iii) proposição do modelo conceitual; (iv) elaboração do estudo de caso; (v) formulação das conclusões do caso e recomendações para as entidades envolvidas. Destacam-se como resultados da pesquisa: (i) a indicação dos documentos críticos nas fases FEED e executiva dos respectivos projetos; (ii) o mapeamento dos principais erros oriundos da incompatibilização entre as disciplinas envolvidas ou decorrentes do não atendimento a requisitos de normas e regulamentos técnicos aplicáveis; e (iii) a proposição de recomendações para as entidades envolvidas. Como conclusão, a pesquisa indica que o modelo conceitual proposto mostrou-se adequado para os fins a que se destina, constituindo um importante instrumento de gestão que poderá ser disseminado em outros contextos organizacionais de avaliação da conformidade de projetos de engenharia. / [en] The objective of this dissertation is to analyze to what extent the conformity assessment of engineering projects in large buildings, conducted according EPC regime, can be used as a tool for organizational learning by the entities involved (contractor, business EPC; subcontractors and certification). In the organizational context in which the research takes place, the objects of analysis are the projects of three waterway terminals of the Transpetro: (i) Pecém - Tecém (CE); (ii) Barra do Riacho (ES); and (iii) Ilha Comprida (RJ) and the main unit is the Unit Implementation of Projects for Transpetro (IETR) from Petrobras. The method comprises: (i) bibliographic and documentary research on the central themes, (ii) selecting the type of case and delimitation of the unit case, (iii) propose of a conceptual model, (iv) preparation of case study, (v) formulation of conclusions and recommendations of the case to entities involved. Stand as the search results: (i) an indication of critical documents in phases FEED and executive of the respective projects, (ii) the mapping of the principal errors that come from the incompatibility between the disciplines involved or arising from the unmet requirements of applicable standards and technical regulations; (iii) to propose recommendations for the entities involved. In conclusion, the research shows that the suggested model was adequate for the purposes for which it is intended, constituting an important management tool and learning that could be disseminated in other organizational contexts of conformity assessment of engineering projects.

Submitted by Nadir Basilio (nadirsb@uninove.br) on 2016-06-21T14:43:39Z No. of bitstreams: 1 LeonardoVils.pdf: 1317899 bytes, checksum: 72185e376a3439d97442d46618097bf6 (MD5) / Made available in DSpace on 2016-06-21T14:43:39Z (GMT). No. of bitstreams: 1 LeonardoVils.pdf: 1317899 bytes, checksum: 72185e376a3439d97442d46618097bf6 (MD5) Previous issue date: 2015-03-05 / Two experiments based on principles of Darwin´s Sexual Selection and assumptions of Evolutionary Psychology, evaluate the tendency to conspicuous display of men and women in romantic stimulus conditions. The first experiment, 2x2 between subjects, indicates that men and women tend to a larger conspicuous display by choosing more risky sports activities, under romantic motives of short-term than long-term. As part of this propensity for exhibitionism, the second experiment, 4x2 between subjects, indicates that men and women, stimulated by short-term romantic motives, show a preference for differentiation messages when promoting services, showing an increase of competitiveness in the search for a casual partner than for the search for a lasting relationship. This study contributes to the understanding of consumer behavior under emotional stimuli of the same positive valence, and it relationship with different choices motivated by interest in short and long term relationships. / Dois experimentos baseados em princípios da Seleção Sexual de Darwin e em pressupostos da Psicologia Evolucionista, avaliam a tendência a exibição conspícua de homens e mulheres sob estímulo de condições românticas. O primeiro experimento, 2x2 entre sujeitos, indica que homens e mulheres tendem a uma maior exibição por meio da escolha de atividades esportivas mais arriscadas, sob motivações românticas de curto prazo do que de longo prazo. Como parte desta propensão ao exibicionismo, o segundo experimento, 4x2 entre sujeitos, indica que homens e mulheres, estimulados por motivações românticas de curto prazo, demonstram a preferência por mensagens de diferenciação quando da promoção de serviços, evidenciando uma maior tendência à competitividade na busca por um(a) parceiro(a) casual do que na busca por um relacionamento duradouro. Este estudo contribui para o entendimento do comportamento do consumidor, sob estímulos emocionais de mesma valência, positiva, em sua relação com escolhas distintas motivadas pelo interesse em relacionamentos de curto e de longo prazo.

Orientador: Marco Antônio Rodrigues Fernandes / Resumo: Os modernos sistemas de planejamentos de tratamento (Treatment Planning System - TPS) computadorizados possibilitam a análise de parâmetros que informam sobre a homogeneidade (Índice de Homogeneidade - IH) e a conformidade (Índice de Conformidade - IC) da distribuição de dose de radiação em todo o volume irradiado. O IH é determinado verificando o gradiente de dose de radiação em todo o volume de tratamento planejado (PTV), uma distribuição de dose perfeitamente homogênea implica em IH igual a zero. O IC representa o grau de conformidade entre a região do PTV coberta pela dose prescrita e o volume total do PTV, quanto mais próximo do valor 1,0 melhor a conformidade do tratamento. Nesta pesquisa foram analisados os índices IH e IC para 82 casos clínicos de pacientes anteriormente submetidos à radioterapia, comparando os valores calculados destes parâmetros em planejamentos realizados com a técnica radioterápica tridimensional conformacional (3D-CRT) com a técnica de radioterapia de intensidade modulada (IMRT), e correlacionando estes índices com a dose de radiação preconizada em cada um dos casos clínicos estudados. Os planejamentos radioterápicos foram efetuados em dois diferentes Sistemas de Planejamento de Tratamento (TPS), o TPS Eclipse e o TPS XiO. Os resultados apontam que os planejamentos feitos com a técnica de IMRT apresentam valores de IC e IH levemente melhores do que os obtidos com a técnica 3D-CRT. / Abstract: Modern Treatment Planning System (TPS) computerized allows the analysis of parameters that report on the homogeneity index (HI) and conformity index (CI) of radiation dose distribution throughout the irradiated volume. IH is determined by checking the radiation dose gradient across the PTV (planned treatment volume), a perfectly homogeneous dose distribution implies IH = zero. The IC represents the degree of conformity between the PTV region covered by the prescribed dose and the total PTV volume, the closer to 1.0 the better the treatment compliance. In this research IH and IC indices were analyzed for 82 clinical cases previously submitted to radiotherapy, comparing the calculated values of these parameters in three-dimensional conformal radiation therapy (3D-CRT) planning with the intensity modulated radiation therapy (IMRT) technique, and correlating these indices with radiation dose recommended in each of the clinical cases studied. Radiotherapy planning was carried out in two different treatment planning system (TPS): TPS Eclipse and TPS XiO. The results indicated that the plans made with the IMRT technique present slightly better IC and IH values than those obtained by 3DCRT technique. / Mestre

The thesis deals with the introduction of the measuring instrument SVA - M on the market for compliance with electromagnetic compatibility and electrical safety requirements. Furthermore it deals with determination of measuring accuracy instrument SVA - M and measurement uncertainties. For the determination of accuracy there is a theoretical analysis and subsequent practical measurements.

The products, which can be labelled with a mark of conformity are included in regulated sphere and they have to ful fill the given requirments before makrket introduction. This diploma thesis is dealing with the aspects which have to fulfilled before the nonautomatic weighing instruments from are introduced to the market. The diploma thesis also revises current methods and proceeds of conformity assessment on ES workplace of conformity assessment accordin to appropriate norms, documents and directives. The aim is also to make a new quality manual for the ES workplace of conformity assessment.