Made available in DSpace on 2017-07-10T17:55:40Z (GMT). No. of bitstreams: 1 Valdir_Sessi.pdf: 4023143 bytes, checksum: 51723604c0f7d7539d0da4fc18de2e84 (MD5) Previous issue date: 2015-08-19 / This dissertation seeks to study the organization and the activity of repressive apparatus formed by Binational Itaipu Security Agencies and the UNICON Consortium from 1974 to 1987. For this research, cases have been selected which involved workers and were produced by these agencies offices, besides narratives of workers and security guards of these agencies. In this sense, the study starts with a discussion about the military origin of these agents, as well as the militarization of those bodies of security. This discussion in the first chapter allowed, throughout the study, to approach the military rigging at that time dictatorship to the action of these agencies. So, the incidence of torture against workers at the Construction Site and on the areas intended to be used as their home was endorsed by a broader power which exceeded the Construction Site itself. In this context, military or paramilitary training of these agents has provided meaning to the transformation of Binational Itaipu complex to a "Total Institution". The police world formed around these agencies or small military units had a purpose, i.e., beyond maintenance of order, to create a consensus among the mass of workers that they were all the time being monitored and their actions liable to punishment. If there were these characteristics of military and constant vigilance in society, it was also necessary to bring to the Construction Site, in terms of bureaucracy and practices, the same procedures adopted by regular police apparatus. This was the way that these security agencies kept the sign of torture and repression against common workers during the construction of the dam. The receipts of people which were commonly exchanged between the police agencies, by the delivery and the receiving from arrested individuals, were also adopted by these militarized sectors of Itaipu. In this way, it was coronated a complex scheme of repression connected to other entities which formed the basis of national information communities. If in the early chapters the study has intensified the analysis of police rigging around the Construction Site, in the following chapters it leaves the pure scope of militarization. In this other approach, the dynamics of hiring and the different ways that the job-seekers arrived at the contractors recruitment center are studied. Many workers already had a profession, and for these ones the hiring was facilitated. However, there were those who tried to get a job with no qualification at all, because they had come from other production branches which were in decadence, mainly from agriculture. In this sense, the diversification of the origin of the workers will be examined, demystifying the figure of the "barrageiro" (Dam-man) attributed by the official history to all those who worked on the construction of the Itaipu s Dam. Not everyone who came and sat as workers for UNICON Consortium and other contractors, forming the irregular subdivisions of Foz do Iguaçu in Paraná state, were barrageiros (dam-men). In this context, many were rushing into an oppressive and strange work modality. Not enough the hard and stressing journey of work under the gaze of the overseers and security guards, men were recklessly victimized by accidents at work: as the "cathedrals of concrete" came up higher, increased the number of accidents, the repression, the widows and orphans who migrated with other unemployed to the local informality Finally, the uprisings of these workers who entered in the "Total Institution" were studied. Many problems referring to coercion and control lasted dispersed or asleep until the end of the military government in 1985. After this period of junction in trade unions (1986), the workers protested against the excesses of the contractors. However, it was in this already democratic moment, more precisely in 1987, that the "barrageiros" (dam-men) were harshly repressed by the public forces. For this purpose, these forces were helped by secret information produced by the remains of Itaipu Security Advising. This uprising indicated what was happening in other strikes in Brazil. The more the National Constituent Assembly was announced, more and more the repression against social movements increased as occurred in the Itaipu s Dam and it was discussed in the last chapter / Esta dissertação objetiva estudar a organização e a atuação dos aparelhos repressores, formados pelas Agências de Segurança da Itaipu Binacional e pelo Consórcio UNICON, durante o período de 1974 a 1987. Para a realização desta pesquisa, foram selecionadas ocorrências que envolviam os trabalhadores e produzidas pelas secretarias dessas mesmas agências, além de narrativas de trabalhadores e guardas de segurança, pertencentes a esses aparelhos. Neste sentido, o estudo inicia-se com a discussão acerca da origem militar dos agentes, bem como sobre a militarização dos corpos de segurança de cada uma delas. Esta discussão, presente no primeiro capítulo, permitiu, ao longo do estudo, aproximar o aparelhamento militar da ditadura vigente à atuação das referidas agências. Assim, a incidência de torturas contra os trabalhadores, no Canteiro de Obras e nas áreas destinadas à moradia dos trabalhadores, era endossada por um poder mais amplo e que transcendia o próprio Canteiro de Obras. Neste contexto, percebe-se que a formação militarizada ou paramilitar desses agentes deu sentido à transformação do complexo da Itaipu Binacional em uma Instituição Total . O mundo policial que se formou em torno dessas agências ou pequenas Unidades Militares tinha uma finalidade, isto é, para além da manutenção da ordem, criar um consenso entre a massa de trabalhadores de que eles estavam todo o tempo sendo vigiados e de que suas ações eram passíveis de punições. Se havia essas características militares e de constante vigilância na sociedade externa ao Canteiro de Obras, necessitava-se, também, de trazer para a usina, em termos de burocracia e práticas, os mesmos procedimentos adotados pelos aparelhos policiais regulares. Assim, as referidas Agências de Segurança mantiveram o signo da tortura e da repressão contra os trabalhadores comuns, durante o tempo que durou a construção da barragem. Os recibos de pessoas, comumente trocados entre os órgãos policiais, quando da entrega e recebimentos de indivíduos presos, foram também adotados pelos setores militarizados da Itaipu. Coroava-se, desta maneira, um complexo esquema repressivo que se mantinha ligado às demais entidades formadoras da base das Comunidades de Informações nacionais. Se, nos primeiros capítulos, o estudo intensificou a análise do aparelhamento policialesco em torno do Canteiro de Obras; nos momentos seguintes, sai da esfera da militarização. Desta outra perspectiva de abordagem, é estudada a dinâmica das contratações e das diversas maneiras que os candidatos a um emprego chegavam ao Centro de Recrutamento das empreiteiras. Muitos trabalhadores tinham uma profissão, e por isso a contratação deles era facilitada. Contudo, havia aqueles que se aventuravam sem qualificação, pois eram oriundos de outro ramo produtivo que estava em decadência, principalmente o da agricultura. Neste sentido, analisa-se a diversificação da origem dos trabalhadores, desmistificando a figura do barrageiro , atribuída pela história oficial a todos aqueles que trabalharam na construção da Usina da Itaipu. Nem todos que vieram e se assentaram como trabalhadores do Consórcio UNICON e em outras empreiteiras, formando os loteamentos irregulares do município de Foz do Iguaçu, no Estado do Paraná, eram barrageiros . Neste contexto, muitos se lançavam a uma modalidade de trabalho opressiva e estranha. Não bastassem as duras e estafantes jornadas de trabalho, sob o olhar dos feitores e dos Guardas de Segurança, os homens eram vitimados pelos acidentes de trabalho: conforme subiam as catedrais de concreto , aumentavam-se os acidentes, a repressão, as viúvas e os órfãos, que migravam com os demais desempregados para a informalidade local. Por fim, foram estudados os levantes desses trabalhadores inseridos na Instituição Total . Muitos problemas referentes à coerção e ao controle ficaram dispersos ou adormecidos até o término do Governo Militar em 1985. Após o referido período de agremiação em sindicatos (1986), os trabalhadores insurgiram-se contra os desmandos das empreiteiras. Porém, nesse momento do período já democrático , mais precisamente em 1987, os barrageiros foram duramente reprimidos pelas forças públicas. Para isto, tais forças foram auxiliadas pelas informações secretas, produzidas pelo que restava da Assessoria de Segurança de Itaipu. Este levante foi o indicador do que acontecia nas demais greves em todo o Brasil. Quanto mais se anunciava a Assembleia Nacional Constituinte, mais se aumentava a repressão aos movimentos sociais, tal como ocorreu na Usina de Itaipu e que foi problematizado no decorrer do último capítulo dessa dissertação

Made available in DSpace on 2017-07-10T17:56:06Z (GMT). No. of bitstreams: 1 Andreia_Zaparte.pdf: 1893364 bytes, checksum: f553cf46e643491e30b5b810b33bad27 (MD5) Previous issue date: 2011-04-28 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / The present research seeks to understand the engenderment of institutionalized repression against the student movement in the city of Curitiba, Parana, in the period between the years 1964 to 1969, which correspond respectively to the beginning of the military dictatorship in Brazil, and the effective extinction Paranaense Union of Students (UPE) on the dissolution of its patrimony, based on the documents produced and / or archived for Delegacy of Political and Social Order (DOPS). In the context of deployment of military dictatorship, with the coup of 1964 and the National Security Doctrine, with the promulgation of Institutional Acts, Laws and Decrees, installation and strengthening of the repressive apparatus of DOPS, the student entities, then existing Were replaced by entities created by Suplicy Law (Law 4.464/64), dictatorship and tied to no autonomy. In this context, the student movement has fought favorable of the public university, free and quality education, democratic freedom and better living conditions, from dictatorship, imperialism, economic exploitation, the disruption of education in Brazil and repression. So, now considered by the political police as "internal enemies" and, consequently, were monitored and harassed, arrested and many were tortured, others have engaged the leftist movements and acted in hiding, others were killed / A presente pesquisa busca compreender o engendramento da repressão institucionalizada contra o movimento estudantil, na cidade de Curitiba, Paraná, no período compreendido entre os anos de 1964 à 1969, que correspondem, respectivamente, ao início da ditadura militar no Brasil e, a efetiva extinção da União Paranaense dos Estudantes (UPE) com a dissolução do seu patrimônio, tendo por base os documentos produzidos e/ou arquivados pela Delegacia de Ordem Política e Social (DOPS). Na conjuntura de implantação da ditadura militar, com o golpe de Estado de 1964 e a Doutrina de Segurança Nacional, com a promulgação de Atos Institucionais, Leis e Decretos-Lei, montagem do aparato repressivo e fortalecimento da DOPS, as entidades estudantis, até então existentes, foram substituídas por entidades criadas pela Lei Suplicy (Lei 4.464/64), atreladas à ditadura e sem autonomia. Nesse contexto, o movimento estudantil lutou em favor da Universidade pública, gratuita e de qualidade, pela liberdade democrática e melhores condições de vida, contra a ditadura, o imperialismo, a exploração econômica, a desestruturação do ensino no Brasil e a repressão. Assim sendo, passaram a ser considerados pela polícia política como inimigos internos e, por conseqüência, foram vigiados e perseguidos, muitos foram presos e torturados, outros se engajaram a movimentos de esquerda e atuaram na clandestinidade, outros, foram mortos.

Orientador: Marcos Severino Nobre / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciências Humanas / Made available in DSpace on 2018-08-21T14:50:58Z (GMT). No. of bitstreams: 1 Carnauba_MariaErbiaCassia_M.pdf: 988830 bytes, checksum: 44a77280b568e37fc12cec6f295ea821 (MD5) Previous issue date: 2012 / Resumo: O objetivo desta dissertação é estudar a apropriação da psicanálise pela Teoria Crítica de Herbert Marcuse, tendo como ponto de partida sua análise dos conceitos de mais-repressão e princípio de desempenho em Eros e Civilização: Uma interpretação Filosófica do Pensamento de Freud. Marcuse teria derivado estes conceitos daqueles freudianos de Repressão e Princípio de Realidade respectivamente, por não corresponderem mais ao atual estágio de desenvolvimento da sociedade capitalista. Com sua reformulação conceitual, ele resgata a teoria freudiana para argumentar que é possível uma sociedade menos repressiva. Tal perspectiva é problemática, posto que Freud, embora aponte algumas formas de superação da sociedade repressiva, tende a um diagnóstico de aumento da repressão, a ponto de afirmar a possibilidade de autodestruição da civilização. Pretendemos discutir essa metamorfose crítico - conceitual de Marcuse e suas consequências. Nossa hipótese é de que tal apropriação é plausível na medida em que está de acordo com a vertente inaugural da Teoria Crítica de Horkheimer em seu artigo de 1937, no qual afirma que a Teoria Tradicional pode ser apropriada pela Teoria Crítica; desde que possamos fazer uma historicização dos conceitos, trazendo-os sempre para o presente momento, ou seja, ao fazer o diagnóstico de época / Abstract: The objective of this dissertation is to study the appropriation of psychoanalysis by Herbert Marcuse, taking as its starting point an analysis of the concepts of surplus repression and the performance principle in Eros and Civilization: A Philosophical Inquiry into Freud. Marcuse would have derived these concepts from the Freudian Repression and the Reality Principle respectively, which do not correspond to the current stage of development of capitalist society anymore. With his conceptual reformulation, he rescues the Freudian theory to argue that a society which is less repressive is possible. This perspective presents a problem since Freud's times, but it suggests some ways of overcoming the repressive society, tends to a diagnosis of increased repression, to the point that the possibility of destruction of civilization. We intend to discuss this critical conceptual metamorphosis of Marcuse and its consequences. Our hypothesis is that such appropriation is plausible insofar as is consistent with the slope of the inaugural Critical Theory Horkheimer in their 1937 article, in which he states that the Traditional Theory can be appropriated by Critical Theory, provided we can historicizing concepts, bringing them ever to nowadays, to make the diagnosis of time / Mestrado / Filosofia / Mestre em Filosofia

Orientador: David de Carvalho / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Civil, Arquitetura e Urbanismo / Made available in DSpace on 2018-08-21T18:16:08Z (GMT). No. of bitstreams: 1 Vidal_EricoCristiano_M.pdf: 3859891 bytes, checksum: d83224508eeb648044f6e4e9a13fea05 (MD5) Previous issue date: 2012 / Resumo: A habitação popular sempre se destacou como uma das principais prioridades dos programas de governo, entretanto, quase sempre sua construção foi mais voltada ao número de unidades do que ao atendimento às normas e às boas técnicas de engenharia. Os resultados, em inúmeros casos, são imóveis com elevada incidência de patologias, comprometidos em suas condições de segurança e habitabilidade. Tais observações motivaram o presente estudo, cujo objetivo é identificar a origem e a extensão de patologias das construções, em particular, o mau desempenho de coberturas e de fundações, confrontando o comportamento dos elementos de transmissão de carga ao solo ao tipo adotado e ao efeito de colapso do solo. Dessa forma, norteados pelo prévio conhecimento da incidência de alguma patologia e da existência de documentos para subsídio de ações judiciais de indenização securitária, estudou-se, de um total de 9.363 unidades habitacionais, 589 imóveis existentes em 13 Conjuntos Habitacionais de Bauru - SP e região. Esse acervo de informações proporcionou ferramentas para apresentar um panorama geral da ocorrência de patologias e as causas que deram origem aos danos, em especial aos recalques de fundação e deformações na estrutura das coberturas que, conforme resultados, chegam a atingir 66,9% e 97,8% do total dos imóveis pesquisados, respectivamente. Como solução, sugeriu-se a compactação adequada do solo de apoio das fundações, além de outros cuidados práticos visando à redução de incidência de patologias em edificações desse porte. Almeja-se que a análise dos problemas constatados possa contribuir para maior responsabilidade na construção civil, resultando em edificações mais seguras e adequadas à população de média e baixa renda do país / Abstract: The popular habitation always stood out like one of the main priorities of the government's programs, however, almost of constructions were focused on the quantity of buildings than fulfilling the standards and good techniques of engineering. The results, in most of the cases, are houses with high number of pathologies, jeopardized in safety and livability conditions. These remarks are the motivation for this present study, whose objective is to identify the origin and extension of constructions pathologies, in particular, the bad performance of roofs and foundations, confronting the performance of load transmission elements to the soil to the type adopted and to the collapse effect of the soil. In this way, guided by the prior knowledge of the incidence of housing pathologies and the existence of documents to support lawsuits, have been studied, from a total of 9.363 housing units, 589 buildings existing in 13 Housing Complexes of Bauru - SP and region. This collection of information has provided tools in order to present a general overview over the occurrences of pathologies and the origins that caused such damages, specially the settlements of the foundations and deformations on the roofs structures of the houses, according to results, they can reach 66,9% to 97,8% of the total of the buildings studied, respectively. As a solution it was suggested the adequate soil compaction supporting the foundations, besides others practical cares aiming to reduce the incidence of pathologies in edifications of this size. It is expected that the analyses of the listed problems can contribute for higher responsibility in civil constructions, resulting in safety and appropriated buildings to medium and low-income population of the country / Mestrado / Geotecnia / Mestre em Engenharia Civil

No description available.

Magister Legum - LLM

Les P-bodies sont des granules cytoplasmiques de fonction inconnue. Ils sont néanmoins conservés de la levure à l’homme, suggérant un rôle important chez les eucaryotes. L’analyse de l’influence de l’expression de certaines protéines pouvant se localiser dans ces granules a permis de mettre en évidence le rôle crucial de DDX6 dans l’assemblage des P-bodies. En effet, l’inhibition de l’expression de DDX6 dans les cellules humaines empêche l’assemblage des P-bodies. L’étude de la protéine DDX6 semblait donc être un bon point de départ pour comprendre d’avantage le rôle des P-bodies. Cette hélicase à motif DEAD de 54 kDa interagit avec des protéines du complexe répression de la traduction CPEB chez le Xénope, mais également avec des protéines des complexes de dégradation 5’-3’ et 3’-5 ‘ des ARNm chez les mammifères, les levures et les drosophiles, ou encore avec les protéines Argonautes du complexe miRISC chez les mammifères. Nos travaux se sont donc intéressés à déterminer les principales fonctions de DDX6 dans les cellules humaines. Les complexes protéiques contenant DDX6 ont été purifiés à partir de lysats cytoplasmiques de cellules HEK293 transfectées avec un plasmide codant pour la protéine FLAG-DDX6-HA. Plus de 300 partenaires protéiques ont été identifiés en spectrométrie de masse. Trois complexes majeurs contenant DDX6 ont été mis en évidence : un complexe de répression « CPEB-like », le complexe de décoiffage des ARNm, et un complexe contenant les ataxin-2 et ataxin-2-like. Les protéines du cœur du complexe de jonction d’exons sont également en interaction avec DDX6, suggérant que DDX6 interagit avec des ARNm tout juste sortis du noyau. Enfin, le grand nombre et les hauts scores avec lesquels ont été identifiés les protéines ribosomales nous ont conduit à analyser la présence de DDX6 au niveau des polysomes. L’analyse de lysats cytoplasmiques sur gradient de sucrose nous a permis de mettre en évidence l’association d’une fraction de DDX6 aux polysomes. Toutes ces observations mettent en évidence le rôle multiple de DDX6 entre répression et dégradation des ARNm, dans les cellules humaines. L’hélicase pourrait permettre le recrutement du complexe de répression par des ARNm activement traduits. La fixation multiple de DDX6 à l’ARNm pourrait être un moyen de recruter simultanément les complexes de répression et de dégradation des ARNm sur un même ARNm. / P-bodies are cytoplasmic granules. Their function is unknown, but they are conserved from the yeast to humans, suggesting an important role through eukaryotes. The expression inhibition of several proteins localized in P-bodies leads to their disassembly. In most cases, a cellular stress induced by arsenite treatment causes P-body assembly, except in cells depleted for DDX6. Since this observation showed that DDX6 is necessary for P-body assembly, to study this protein is a good starting point to further understand the role of P-bodies. This 54 kDa DEAD-box helicase interacts with proteins of the CPEB repression complex in xenopus oocytes, but also with protein of the déadénylation and dacapping complex in yeasts, drosophila and mammals, and with proteins of the miRISC complex. Our project was to determine the DDX6 main protein partners in human cells. To do so, DDX6 containing complexes were purified using HEK293 cells transfected with a plasmid encoding for the FLAG-DDX6-HA. Over 300 partners were identified by mass spectrometry. Three main DDX6 containing complexes were highlighted in human cells: A “CPEB-like” repression complex, the decapping complex, and a complex containing ATXN2 and ATXN2L proteins. Exon junction complex core proteins were also identified as DDX6 partners, raising the possibility that DDX6 interacts with mRNA not yet translated. A large number of ribosomal proteins were also identified with high scores, suggesting that DDX6 interacts with actively translated mRNA. Analyze of cytoplasmic lysates on sucrose gradients showed that DDX6 is partially associated with polysomes. To conclude, these observations showed the multiple roles of DDX6 in human cell, between mRNA repression and degradation. The helicase could allow the recruitment of the repression complex on actively translated mRNA. In a nutshell, the multiple binding of DDX6 on one mRNA could be a way to enable the fixation of repression and degradation complexes at the same time, on the same mRNA.

No description available.

De nombreux gènes suppresseurs de tumeurs sont inactivés par hyperméthylation dans les cancers. Cette inactivation serait en partie initiée par la protéine, MBD2 (Methyl-CpG-Binding Domain protein 2). Cette protéine recrute au niveau de séquences méthylées des complexes enzymatiques capables de modifier la structure chromatinienne et crée ainsi des régions fonctionnellement inactives. Dès lors, ce répresseur apparaît être une cible potentielle pour combattre le cancer. Dans cette perspective, rechercher les cibles de MBD2 et comprendre sa capacité à contrôler l’expression génique semblent cruciales. Au cours de deux études gènes candidats, nous avons pu démontrer (i) une réelle spécificité de cible du répresseur méthylationdépendant MBD2 pour les loci hTERT et pS2/TFF1 ; et (ii) un nouveau rôle de la protéine MBD2 en tant que modulateur de l’expression génique. De plus, les actions antagonistes entre le répresseur MBD2 et le trans-activateur naturel du gène pS2, le récepteur aux oestrogènes α, ont été explorées. Puis, l’analyse globale des profils de distribution de MBD2, de la méthylation de l’ADN, ainsi que de l’ARN polymérase II, sur puce promoteur a montré que MBD2 possède toutes les caractéristiques d’un répresseur trancriptionnel méthylation-dépendant. En effet, 74% des promoteurs fixés par MBD2 sont méthylés et cette liaison est associée dans 65% des cas à une répression transcriptionnelle. / In the past few years, several clinical trials have shown that targeting DNA methylation machinery might be of interest in cancer therapy to restore tumor suppressor genes expression and inhibit tumor growth. The Methyl-CpG-Binding Domain protein 2 (MBD2) is an important constituent of the DNA methylation machinery since this protein is directly involved in the mediation of the epigenetic signal. Moreover, MBD2 seems to show some gene specificity, its inhibition reactivate a limited number of genes. Taken together these data suggest that MBD2 represents potential new target in cancer therapy and, therefore, new insights on MBD2 specificities are, in this context, of importance. To this end, we have developed two different approaches: a candidate genes analysis and a genome-wide analysis, using ChIP-on-chip method, in order to map MBD2 binding sites. The candidate gene approaches are strongly in favour of the “one gene – one MBD” hypothesis, at least for the genes analyzed. Indeed, our results indicate that MBD2 is specifically and directly involved in the transcriptional repression of hTERT and pS2/TFF1 genes. Furthermore, a new role of MBD2 in the fine-scale modulation of these genes was demonstrated, and the antagonist actions between MBD2 and the natural trans-activator of pS2 gene, the estrogen α, were explored. Genome wide distribution of MBD2 binding sites, DNA Methylation profiles, and silencing potential, showed that the MBD2 is a real methylation-dependant transcriptional repressor: 74% of the MBD2 binding promoters are methylated and 65% silenced.

This dissertation investigates three questions: First, what conditions make dissident collective action such as protest, revolt, rebellion, or civil war more likely to happen in a country? Second, what conditions make citizens more likely to join in dissident collective action? Third, does Internet use play a role in dissident collective action, and if so, why? I argue that motives and resources are necessary rather than sufficient conditions for dissident collective action. I develop an analytical framework integrating motives and resources. Specifically, I theorize that state repression is an important motive, and that civil society is critical in providing resources. Four statistical analyses are conducted to test the hypotheses. Using aggregate level data on countries over time, I find that civil war is more likely to occur in countries where both state repression and civil society are strong. Moreover, the effect of civil society on civil war onset increases as the repression level rises. at the individual level using 2008 Latin American Public Opinion Project surveys from 23 Latin American and Caribbean countries, I find individuals more likely to join in protest when they experience both more repression and greater civic engagement. Moreover, civic engagement’s effect on protest participation increases as people experience more repression. I further find that Internet use constitutes a kind of civic engagement and has effects similar to voluntary group involvement. the effect of Internet use on protest participation decreases as a person’s civic engagement increases. Finally, an individual is more likely to join in protest when experiencing more repression and using the Internet more frequently. Moreover, the effect of Internet use on protest participation increases as a person experiences more repression.