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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

A study on a Chinese herbal medicine preparation to modulate post-injury swelling of the limb in-vitro and clinical studies. / CUHK electronic theses & dissertations collection

January 2004 (has links)
by Zhao Xin. / "October 2004." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2004. / Includes bibliographical references (p. 235-260) / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.
62

Fördelar och nackdelar med att använda Cone Beam CT som ett diagnostiskt verktyg för frakturer i distala extremiteter / Advantages and disadvantages with using Cone Beam CT as an diagnostic tool for fractures in distal extremities

Valdrina, Kastrati, Wiveson, Caroline January 2018 (has links)
Cone Beam Computed Tomography (CBCT) är en relativt ny modalitet att användas inom ortopedin till olika typer av skador och användningen håller på att öka. Författarna till denna studien har under skolgången endast i liten omfattning stött på denna modalitet, vilket gjorde att deras intresse för att lära sig mer om den var stort. Syftet med den här studien var att sammanställa vilka fördelar och nackdelar modaliteten har vid frakturutredning i extremiteter. Metoden som användes till den här studien var en allmän litteraturstudie, där fakta samlades in från artiklar i olika databaser och även i kurslitteratur. Kvalitetsgranskningen gjordes av båda författarna enligt ett kvalitetsgranskningsprotokoll som var specialutformat för att passa studien bra.  I analysen sammanställdes informationen från artiklarna och kategoriserades för att göra resultatet mer lättöverskådligt. Resultatet visade på att fler frakturer hittas med hjälp av CBCT:n än vad det görs med konventionell röntgen. Detta gällde särskilt scaphoideum-, karpalbens-, och handledsfrakturer. Den visade sig även vara ett hjälpmedel gällande bedömning av instabil eller stabil fotled efter en viss typ av fotledsfraktur. Magnetisk resonans (MR) visade sig var något bättre än CBCT:n på att detektera scaphoideumfrakturer. Frakturdetekteringsförmågan hos CBCT:n var likvärdig som med den hos Multi Detector Computed Tompography (MDCT). Stråldosen ifrån CBCT:n visade sig vara högre än vid konventionell röntgen, men mindre än stråldosen från MDCT:n. CBCT:n var även billigare att köpa in och underhålla än MDCT:n. CBCT:n visade sig ha en vanlig typ av artefakter, som var beam-hardening artefakter och rörelseartefakter. Författarna till denna studien tror att CBCT:n kan vara ett bra komplement till konventionell röntgen vid olika frakturer i extremiteter, men mer forskning behöver göras då området fortfarande är relativt nytt och informationen är begränsad. / Cone Beam Computed Tomography (CBCT) is a relatively new modality to be used in orthopedic for various types of injuries and the usage is increasing. The authors of this study have only encountered this modality a little bit during school, which meant that their interest in learning more about it was big. The purpose of this study was to compile the advantages and disadvantages of this modality in fracture examination in extremities. The method used for this study was a general literature study, where facts were collected from articles in different databases and also in literature. The quality review was done by both authors according to a quality audit protocol that was tailor-made to suit the study well.  In the analysis, the information was compiled from the articles and categorized to make the result more easy to understand. The result showed that more fractures were found using CBCT than conventional X-ray. This was especially true of scaphoidum, carpal, and wrist fractures. It also proved to be an aid in assessing unstable or stable ankle after a certain type of ankle fracture. Magnetic resonance (MR) proved slightly better than the CBCT to detect scaphoid fractures. The fracture detection capability of the CBCT was similar to that of Multi Detector Computed Tompography (MDCT). The radiation dose from the CBCT was found to be higher than in conventional X-rays, but less than the radiation dose from the MDCT. The CBCT was also cheaper to buy and maintain than the MDCT. The CBCT proved to have a common type of artifacts, such as beam-hardening artifacts and movement artifacts. The authors of this study believe that the CBCT may be a good complement to conventional x-ray in various fractures in extremities, but more research needs to be done as this area is still relatively new and the information is limited.
63

A metodologia LMS para modelagem matemática de cartas de referência de valores dinamométricos para avaliação de membros superiores / LMS methodology for mathematical modelling of reference cards of dynamometric values for evaluation of upper limbs

Trotta, Juliano de 31 August 2016 (has links)
As Doenças Osteomusculares Relacionadas ao Trabalho (DORT) são as patologias que demandam atenção das empresas do setor industrial devido à alta incidência de absenteísmo e pela prevalência nos afastamentos previdenciários, sendo os membros superiores o segmento corporal mais atingido. A mensuração da força muscular através da dinamometria é um dos métodos para estimar a capacidade funcional de um indivíduo, porém as tabelas internacionais de valores dinamométricos que são utilizadas como parâmetros de normalidade são conflitantes com a população do setor industrial brasileiro. Neste contexto, percebe-se a necessidade de criar um padrão de normatização específico para o setor da indústria eletromecânica que auxilie a medicina ocupacional na percepção de aptidão para execução de uma atividade laboral, prevenindo o aparecimento de DORT. O objetivo deste estudo é desenvolver valores de normalidade nos exames de dinamometria palmar e escapular através do método de cartas percentílicas, que atendessem a população brasileira do setor industrial, correlacionando com as variáveis: faixa etária, sexo e lado de dominância, para servir de apoio na decisão de aptidão profissional. Para tanto, foi realizado um estudo retrospectivo, descritivo e transversal com 2902 funcionários saudáveis entre 16 e 63 anos, a partir de banco de dados de empresas do setor eletromecânico da região metropolitana de Curitiba. Os dados foram analisados a partir da estatística descritiva com medidas de posição e dispersão e cartas de referência foram elaboradas a partir do método LMS (Least Median Square), sendo L transformação “BoxCox”, M mediana e S coeficiente de variação. Os resultados mostraram que as medianas de dinamometrias palmares desta pesquisa estão abaixo dos estudos internacionais e que as curvas percentílicas formadas pelos valores das dinamometrias desta amostragem apresentam um valor progressivo com a idade. Para o gênero masculino, a metodologia permitiu a formatação de gráficos de que apontam intervalos normalidade de acordo com cada idade. Conclui-se assim, que os valores dinamométricos palmares e escapulares encontrados hoje na literatura internacional não se aplicam para a população do setor eletromecânico nacional. O método de cartas percentílicas relacionadas com a idade e gênero permitiu formatar uma modelagem matemática com gráficos de normalidade, de fácil empregabilidade, que quando relacionado ao grau de risco ergonômico do posto de trabalho auxilia o raciocínio médico quanto a aptidão para assumir uma determinada atividade laboral. Como proposta futura, sugere-se a continuidade de estudos com esta mesma metodologia para o gênero feminino e a associação de outros métodos tecnológicos sensíveis à detecção e prevenção de doenças osteoarticulares relacionadas ou não, com o trabalho, como a termografia / The Musculoskeletal Diseases related to work (WRMD) are the pathologies that require attention of companies in the industrial sector due to high incidence of absenteeism and the prevalence in through INSS, and the upper limbs the most affected body part. The measurement of muscular strength by grip strength is one of the methods to measure the functional capacity a person, but international tables dynamometric values that are used as normal parameters are conflicting with the population of the Brazilian industrial sector. In this context, we see the need to create a specific standards model for the electromechanical industry sector to assist occupational medicine to check the capability to execute a labor activity, preventing from DORT. The aim of this study is to develop normal values for palmar grip strength and scapular tests by percentile cards method that met the Brazilian population in the industrial sector, correlating to the variables: age, gender and hand dominance, to provide support in the fitness professional decision. A retrospective, descriptive cross-sectional study was made with 2902 healthy employees between 16 and 63 years from database of electromechanical companies of the Curitiba metropolitan area. The data was analyzed using descriptive statistics with position and dispersion measurements and reference cards have been elaborated from the LMS method (Least Median Square), where L is transformation "BoxCox", M is median and S is coefficient of variation. The results showed that the median grip dinamometric of this research are below international studies and that percentílicas curves formed by the values of dinamometrias this sample have a progressive value with age. This methodology for the male gender allowed the formatting charts that show normal ranges according to each age. It was concluded that the dynamometric values grip and scapular found today in the international literature are contradictory when applied to the population of the national electromechanical industry. Percentile cards method related to age and gender, it was possible to format a mathematical modeling with normal graphics, easy usage, when related to the degree of ergonomic risk of working location aids medical thinking as the ability to take a certain labor activity. As a future proposal, it is suggested to continue their studies with the same methodology for the female gender and the association of other technological methods sensitive to the detection and prevention of osteoarticular diseases related or not with work, as thermography.
64

A metodologia LMS para modelagem matemática de cartas de referência de valores dinamométricos para avaliação de membros superiores / LMS methodology for mathematical modelling of reference cards of dynamometric values for evaluation of upper limbs

Trotta, Juliano de 31 August 2016 (has links)
As Doenças Osteomusculares Relacionadas ao Trabalho (DORT) são as patologias que demandam atenção das empresas do setor industrial devido à alta incidência de absenteísmo e pela prevalência nos afastamentos previdenciários, sendo os membros superiores o segmento corporal mais atingido. A mensuração da força muscular através da dinamometria é um dos métodos para estimar a capacidade funcional de um indivíduo, porém as tabelas internacionais de valores dinamométricos que são utilizadas como parâmetros de normalidade são conflitantes com a população do setor industrial brasileiro. Neste contexto, percebe-se a necessidade de criar um padrão de normatização específico para o setor da indústria eletromecânica que auxilie a medicina ocupacional na percepção de aptidão para execução de uma atividade laboral, prevenindo o aparecimento de DORT. O objetivo deste estudo é desenvolver valores de normalidade nos exames de dinamometria palmar e escapular através do método de cartas percentílicas, que atendessem a população brasileira do setor industrial, correlacionando com as variáveis: faixa etária, sexo e lado de dominância, para servir de apoio na decisão de aptidão profissional. Para tanto, foi realizado um estudo retrospectivo, descritivo e transversal com 2902 funcionários saudáveis entre 16 e 63 anos, a partir de banco de dados de empresas do setor eletromecânico da região metropolitana de Curitiba. Os dados foram analisados a partir da estatística descritiva com medidas de posição e dispersão e cartas de referência foram elaboradas a partir do método LMS (Least Median Square), sendo L transformação “BoxCox”, M mediana e S coeficiente de variação. Os resultados mostraram que as medianas de dinamometrias palmares desta pesquisa estão abaixo dos estudos internacionais e que as curvas percentílicas formadas pelos valores das dinamometrias desta amostragem apresentam um valor progressivo com a idade. Para o gênero masculino, a metodologia permitiu a formatação de gráficos de que apontam intervalos normalidade de acordo com cada idade. Conclui-se assim, que os valores dinamométricos palmares e escapulares encontrados hoje na literatura internacional não se aplicam para a população do setor eletromecânico nacional. O método de cartas percentílicas relacionadas com a idade e gênero permitiu formatar uma modelagem matemática com gráficos de normalidade, de fácil empregabilidade, que quando relacionado ao grau de risco ergonômico do posto de trabalho auxilia o raciocínio médico quanto a aptidão para assumir uma determinada atividade laboral. Como proposta futura, sugere-se a continuidade de estudos com esta mesma metodologia para o gênero feminino e a associação de outros métodos tecnológicos sensíveis à detecção e prevenção de doenças osteoarticulares relacionadas ou não, com o trabalho, como a termografia / The Musculoskeletal Diseases related to work (WRMD) are the pathologies that require attention of companies in the industrial sector due to high incidence of absenteeism and the prevalence in through INSS, and the upper limbs the most affected body part. The measurement of muscular strength by grip strength is one of the methods to measure the functional capacity a person, but international tables dynamometric values that are used as normal parameters are conflicting with the population of the Brazilian industrial sector. In this context, we see the need to create a specific standards model for the electromechanical industry sector to assist occupational medicine to check the capability to execute a labor activity, preventing from DORT. The aim of this study is to develop normal values for palmar grip strength and scapular tests by percentile cards method that met the Brazilian population in the industrial sector, correlating to the variables: age, gender and hand dominance, to provide support in the fitness professional decision. A retrospective, descriptive cross-sectional study was made with 2902 healthy employees between 16 and 63 years from database of electromechanical companies of the Curitiba metropolitan area. The data was analyzed using descriptive statistics with position and dispersion measurements and reference cards have been elaborated from the LMS method (Least Median Square), where L is transformation "BoxCox", M is median and S is coefficient of variation. The results showed that the median grip dinamometric of this research are below international studies and that percentílicas curves formed by the values of dinamometrias this sample have a progressive value with age. This methodology for the male gender allowed the formatting charts that show normal ranges according to each age. It was concluded that the dynamometric values grip and scapular found today in the international literature are contradictory when applied to the population of the national electromechanical industry. Percentile cards method related to age and gender, it was possible to format a mathematical modeling with normal graphics, easy usage, when related to the degree of ergonomic risk of working location aids medical thinking as the ability to take a certain labor activity. As a future proposal, it is suggested to continue their studies with the same methodology for the female gender and the association of other technological methods sensitive to the detection and prevention of osteoarticular diseases related or not with work, as thermography.
65

Ergonomic product development within dentistry : An empirical study with focus on strain issues in the hand-/armextremities, and recommendations for future product development / Ergonomisk produktutveckling inom tandvården : En empirisk studie med fokus på belastningsbesvär i hand-/armregionen och rekommendationer för framtida produktutveckling

Hedberg, Ebba, Laurent, Emelie January 2022 (has links)
This report presents a Master of Science Thesis, conducted at the Royal Institute of Technology, within Industrial Design Engineering, in collaboration with the privately owned healthcare company Praktikertjänst AB. The purpose of this project was to investigate the distribution of injuries and issues in the hand-/arm extremities among dentistry personnel, as well as explore the possibility to prevent these to emerge. Through literature studies, field visits and empirical methods, valuable insights have been obtained. These were processed and resulted in recommendations for future product development including suggestions of solutions, and a checklist for clinics which they can use to prevent strain issues from occurring. The result shows that work-related strain issues in the hand-/arm extremities exist to a large extent among dentistry personnel. Most dentistry personnel with hand-/arm problems experience pain in their fingers and wrist on their right-hand side. Then, it is most common with strain injuries in the fingers and wrist, where the three most specified injuries were thumb arthritis, carpal tunnel syndrome and lateral epicondylitis. Moreover, the most common symptoms were cold hands, numbness, and impaired grip. However, these symptoms were not connected to a specific injury. The underlying causes of these issues are many but could be reduced by ergonomic product development and human centered design. Furthermore, it would be interesting to examine the impact of vibrations, since symptoms of vibration syndromes can be seen, and few respondents have specified a diagnosis. Also, the result shows that there are presumably unrecorded cases in national statistics considering work related injuries. Whether the result can be generalized for the whole dental care sector or not is difficult to determine, since most of the material was gathered from the private sector. Therefore, it would be of great interest to carry out a similar study within the regional dentistry. / Denna rapport redovisar ett masterexamensarbete utfört på Kungliga Tekniska Högskolan, inom Teknisk Design, i samarbete med det privata vårdbolaget Praktikertjänst AB. Syftet med projektet var att undersöka utbredningen av skador och problem i hand-/armregionen hos tandvårdspersonal, samt utforska möjligheten att förebygga uppkomsten av dessa besvär. Med hjälp av litteraturstudier, studiebesök och empiriska metoder har värdefulla insikter erhållits. Dessa har sedan bearbetats och resulterat i rekommendationer för framtida produktutveckling innehållande lösningsförslag, samt en checklista för kliniker som kan hjälpa till att förebygga belastningsbesvär. Resultatet visar att det i stor utsträckning förekommer arbetsrelaterade belastningsbesvär i hand-/armregionen hos tandvårdspersonal. För de med hand-/armproblem är smärta vanligast att uppleva i fingrar och handled på höger sida. Sedan förekommer flest belastningsskador i fingrar och handled, där de tre mest specificerade skadorna är artros i tummen, karpaltunnelsyndrom och tennisarmbåge. Vidare är de vanligaste symtomen kalla händer, domningar och försämrad gripkraft. Dessa symtom i hand/arm är dock inte kopplade till någon specifik skada. De bakomliggande orsakerna till dessa besvär är många, men skulle kunna reduceras med hjälp av ergonomisk produktutveckling och människocentrerad design. Det vore intressant att närmare undersöka hur vibrationer påverkar dessa besvär, då symtom till vibrationsskador existerar, men få har specificerat en diagnos. Vidare tyder resultatet på att det troligen är ett stort mörkertal i nationell statistik angående arbetsskador. Om resultatet går att generalisera för hela tandvården är svårt att avgöra, eftersom övervägande mängd material har samlats in från privat sektor. Därför vore det intressant att utföra en liknande studie inom Folktandvården.
66

Developing Models to Study Relationships between Tibial Acceleration Measures and Lower Extremity Musculoskeletal Disorder Symptoms Experienced by Distribution Center Workers

Dutt, Mohini 09 June 2016 (has links)
No description available.
67

"Estudo epidemiológico descritivo dos doentes de melanoma cutâneo acompanhados na Unidade de Melanoma da Santa Casa de São Paulo" / Descriptive epidemiological study in cutaneous melanoma patients followed at Melanoma Unit of Santa Casa de São Paulo.

Ferrari Junior, Nelson Marcos 30 August 2006 (has links)
INTRODUÇÃO: O melanoma cutâneo constitui cerca de 3% de todos os tumores da pele. Atinge indivíduos jovens com média de idade de aparecimento entre 50 e 58 anos. Em torno de 20% dos doentes apresentarão doença avançada e morrerão antes de completar cinco anos de sobrevida. CASUÍSTICA E MÉTODOS: Neste estudo retrospectivo de 364 casos acompanhados de maio de 1993 a janeiro de 2006 descreveram-se as variáveis: sexo, idade, cor, localização da lesão primária, tipo de crescimento, espessura de Breslow, nível de Clark, presença de ulceração, estadiamento e suas correlações. RESULTADOS: Predominou o sexo feminino (58,8%) resultando em uma proporção de 1,4 mulheres para cada homem. A média das idades dos pacientes foi de 58,9 anos e a mediana de 61,0 anos. Pacientes não-brancos constituíram 13,7% da amostra. Para homens e mulheres o melanoma cutâneo localizou-se, predominantemente no tronco (24,3-38,0%) e pés (21,4-23,9%). O melanoma acrolentiginoso representou 22,3% de toda amostra. Os padrões melanoma expansivo superficial e melanoma nodular (p < 0,001) e lesões no tronco (52,8%) predominaram nos indivíduos brancos. O melanoma acrolentiginoso (64%) e a localização nos pés (68,2%)prevaleceram nos pacientes não-brancos. Observou-se minoria de casos com lesão primária in situ (14,6%- EC 0) e alto percentual de melanoma cutâneo espesso (39,7% > 4,0 mm). Presença de ulceração foi observada em 13,4% para tumores finos (= 1,0 mm). Homens apresentaram lesões mais espessas (p = 0,011) e ulceradas (p < 0,001) em relação às mulheres, assim como idosos em relação à não idosos (p = 0,021 para a espessura e p = 0,015 para ulceração). A sobrevida média para os pacientes com doença localizada foi de 97,8 meses e a taxa de sobrevida específica para melanoma cutâneo foi de 85,1% em três anos. CONCLUSÕES: Esta amostra constituiu-se de pacientes com tumores espessos e ulcerados denotando diagnóstico tardio do melanoma cutâneo e pior prognóstico. Caracterizou-se por apresentar predomínio de mulheres, de pacientes não-brancos, de lesões nas extremidades e de melanoma acrolentiginoso. / INTRODUCTION: Cutaneous melanoma represents around 3% of all skin tumors. Affecting young patients, with mean age between 50 and 58 years old. About 20% of the patients will have advanced disease and will die before five years of survival. CASUISTIC AND METHODS: In this retrospective study of 364 cases recorded from May 1993 to January 2006 at the Melanoma Unit of Santa Casa de São Paulo the following variables were described: sex, age, skin color, tumor site, growth pattern, tumor thickness, Clark level, ulceration, staging and their correlations. RESULTS: Female (58,8%) prevailed resulting in 1,4 women for each man. The mean age of the patients was 58,9 years old and the median, 61,0 years old. Non-white patients were 13,7% of the sample. The anatomic site of cutaneous melanoma on men and women prevailed at trunk (24,3 – 38,0%) and feet (21,4 – 23,9%). Acral entiginous melanoma represented 22,3% of the cohort. Superficial expansive melanoma and nodular melanoma patterns (p<0,001) and trunk lesions (52,8%) predominated on white patients. Acral lentiginous melanoma (64%) and feet anatomic site 68,2%) prevailed on non-white patients. In situ primary lesions were observed in few cases (14,6% - EC 0) and there was high percentage of thick cutaneous melanoma (39,7% > 4,0 mm). In thin tumors (=1,0 mm) were found 13,4% of ulceration. Thickener (p = 0,011) and ulcerated lesions (p < 0,001) were found more in male and in elderly patients (p = 0,021 for thickeness and p = 0,015 for ulceration). The mean survival of patients with local disease was 97,8 months and the three-year survival rate for cutaneous melanoma was 85,1%. CONCLUSIONS: The cohort consisted mostly of thick and ulcerated tumors, which meant late diagnosis and bad prognosis. Also distinguished by considerable prevalence of female, non-white patients, limb lesions and acral lentiginous melanoma.
68

Entwicklung eines modularen Rehabilitationsverfahrens für Patienten mit Zustand nach Polytrauma der unteren Extremitäten auf der Grundlage sportwissenschaftlicher Gesetzmäßigkeiten / Draft of a modular rehabilitation procedure for patients with post polytrauma states of the lower extremities on the basis of the principles of sport science

Gropengießer, Dirk 19 March 2004 (has links)
No description available.
69

"Estudo epidemiológico descritivo dos doentes de melanoma cutâneo acompanhados na Unidade de Melanoma da Santa Casa de São Paulo" / Descriptive epidemiological study in cutaneous melanoma patients followed at Melanoma Unit of Santa Casa de São Paulo.

Nelson Marcos Ferrari Junior 30 August 2006 (has links)
INTRODUÇÃO: O melanoma cutâneo constitui cerca de 3% de todos os tumores da pele. Atinge indivíduos jovens com média de idade de aparecimento entre 50 e 58 anos. Em torno de 20% dos doentes apresentarão doença avançada e morrerão antes de completar cinco anos de sobrevida. CASUÍSTICA E MÉTODOS: Neste estudo retrospectivo de 364 casos acompanhados de maio de 1993 a janeiro de 2006 descreveram-se as variáveis: sexo, idade, cor, localização da lesão primária, tipo de crescimento, espessura de Breslow, nível de Clark, presença de ulceração, estadiamento e suas correlações. RESULTADOS: Predominou o sexo feminino (58,8%) resultando em uma proporção de 1,4 mulheres para cada homem. A média das idades dos pacientes foi de 58,9 anos e a mediana de 61,0 anos. Pacientes não-brancos constituíram 13,7% da amostra. Para homens e mulheres o melanoma cutâneo localizou-se, predominantemente no tronco (24,3-38,0%) e pés (21,4-23,9%). O melanoma acrolentiginoso representou 22,3% de toda amostra. Os padrões melanoma expansivo superficial e melanoma nodular (p < 0,001) e lesões no tronco (52,8%) predominaram nos indivíduos brancos. O melanoma acrolentiginoso (64%) e a localização nos pés (68,2%)prevaleceram nos pacientes não-brancos. Observou-se minoria de casos com lesão primária in situ (14,6%- EC 0) e alto percentual de melanoma cutâneo espesso (39,7% > 4,0 mm). Presença de ulceração foi observada em 13,4% para tumores finos (= 1,0 mm). Homens apresentaram lesões mais espessas (p = 0,011) e ulceradas (p < 0,001) em relação às mulheres, assim como idosos em relação à não idosos (p = 0,021 para a espessura e p = 0,015 para ulceração). A sobrevida média para os pacientes com doença localizada foi de 97,8 meses e a taxa de sobrevida específica para melanoma cutâneo foi de 85,1% em três anos. CONCLUSÕES: Esta amostra constituiu-se de pacientes com tumores espessos e ulcerados denotando diagnóstico tardio do melanoma cutâneo e pior prognóstico. Caracterizou-se por apresentar predomínio de mulheres, de pacientes não-brancos, de lesões nas extremidades e de melanoma acrolentiginoso. / INTRODUCTION: Cutaneous melanoma represents around 3% of all skin tumors. Affecting young patients, with mean age between 50 and 58 years old. About 20% of the patients will have advanced disease and will die before five years of survival. CASUISTIC AND METHODS: In this retrospective study of 364 cases recorded from May 1993 to January 2006 at the Melanoma Unit of Santa Casa de São Paulo the following variables were described: sex, age, skin color, tumor site, growth pattern, tumor thickness, Clark level, ulceration, staging and their correlations. RESULTS: Female (58,8%) prevailed resulting in 1,4 women for each man. The mean age of the patients was 58,9 years old and the median, 61,0 years old. Non-white patients were 13,7% of the sample. The anatomic site of cutaneous melanoma on men and women prevailed at trunk (24,3 – 38,0%) and feet (21,4 – 23,9%). Acral entiginous melanoma represented 22,3% of the cohort. Superficial expansive melanoma and nodular melanoma patterns (p<0,001) and trunk lesions (52,8%) predominated on white patients. Acral lentiginous melanoma (64%) and feet anatomic site 68,2%) prevailed on non-white patients. In situ primary lesions were observed in few cases (14,6% - EC 0) and there was high percentage of thick cutaneous melanoma (39,7% > 4,0 mm). In thin tumors (=1,0 mm) were found 13,4% of ulceration. Thickener (p = 0,011) and ulcerated lesions (p < 0,001) were found more in male and in elderly patients (p = 0,021 for thickeness and p = 0,015 for ulceration). The mean survival of patients with local disease was 97,8 months and the three-year survival rate for cutaneous melanoma was 85,1%. CONCLUSIONS: The cohort consisted mostly of thick and ulcerated tumors, which meant late diagnosis and bad prognosis. Also distinguished by considerable prevalence of female, non-white patients, limb lesions and acral lentiginous melanoma.
70

BIOMEDICAL APPLICATION OF THERMOCHROMIC LIQUID CRYSTALS AND LEUCO DYES FOR TEMPERATURE MONITORING IN THE EXTREMITIES

Rao, Nilin M., Ph.D. 14 December 2016 (has links)
No description available.

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