Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-01-20T20:31:03Z No. of bitstreams: 1 EduardoAlexandreRibeiroDaSilva_TESE.pdf: 7584123 bytes, checksum: 6455376d66a5f8e328e216308514d115 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-01-20T21:45:01Z (GMT) No. of bitstreams: 1 EduardoAlexandreRibeiroDaSilva_TESE.pdf: 7584123 bytes, checksum: 6455376d66a5f8e328e216308514d115 (MD5) / Made available in DSpace on 2016-01-20T21:45:01Z (GMT). No. of bitstreams: 1 EduardoAlexandreRibeiroDaSilva_TESE.pdf: 7584123 bytes, checksum: 6455376d66a5f8e328e216308514d115 (MD5) Previous issue date: 2014-09-08 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Face ao evidente aumento do contingente populacional das pessoas com mais de 60 anos, o processo do envelhecimento tem levantado importantes debates em ?reas como planejamento social, pol?tico e econ?mico, os quais recomendam que o incremento da longevidade deve estar acompanhado de autonomia e qualidade de vida. Diante dessas demandas, a literatura relata que estar ativo tem sido uma das principais estrat?gias para a promo??o de melhores condi??es de vida aos idosos, e os estudos no campo das rela??es pessoa-ambiente t?m envidado esfor?os para compreender o papel dos diversos tipos de ambiente sociof?sico para a estimula??o da atividade em idosos. Dentre estes, os espa?os abertos urbanos p?blicos tem sido relatados como alternativas promissoras na ado??o de um estilo de vida menos sedent?rio. Com base nessas considera??es, este estudo desenvolveu o conceito de suporte socioambiental e se prop?s a investigar a rela??o entre seus elementos e a intera??o social de idosos em pra?as p?blicas da cidade de Natal-RN. Para tanto foi utilizada uma abordagem multimetodol?gica que incluiu: painel de especialistas, an?lise de caracter?sticas ambientais de 252 pra?as e dois estudos de caso contendo observa??es comportamentais, representa??o espacial dos comportamentos de intera??o social de idosos em pra?as, entrevistas coletivas e individuais com estes usu?rios. A associa??o entre a realiza??o de atividades f?sicas e as formas de socializa??o por eles praticadas foi identificada como o principal agente motivador da presen?a de idosos nesses locais. Os resultados indicam que a interrela??o entre elementos do suporte socioambiental e os comportamentos socioespaciais que envolvem a apropria??o do espa?o - principalmente arranjos espaciais e dist?ncias interpessoais - favorecem o estabelecimento de intera??es sociais relevantes para a estimula??o na realiza??o de atividades, as quais, segundo os pressupostos do Programa do Envelhecimento Ativo, s?o fundamentais para a manuten??o de um estilo de vida ativo, com importantes implica??es para a sa?de, bem estar e qualidade de vida na velhice / In view of the evident increase in the population group of people over 60 years old, the aging process has raised important discussions on social, political and economical planning that recommend that the increase in longevity must be followed by autonomy and well-being. Faced to these demands, the literature reports that physical activity is a key strategy to promote better living conditions for the elderly. Studies about personenvironment are making efforts to understand the socio physical environment role to encourage old people to make activities in many different environments. Among these, the urban public open space has been reported by many researches as a promising alternative in order to adopt a less sedentary life style. Based on these considerations, this study proposed to investigate the relationship between the social environment support elements and social interaction of seniors in public squares in the city of Natal, RN, using a multimethodological approach that included a experts panel, environmental characteristics analysis of 252 squares, case studies containing collective and individual interviews with elderly users and the spatial representation of their social interactions. The association between physical activities with the socialization practiced by them was identified as the main motivation for their presence in these places. The results indicate that the relationship between the socio-environmental characteristics (concept developed in this study) and the socio-spatial behaviors that include the spatial appropriation, spatial arrangements and interpersonal distances, helps to promote social interactions in carrying out activities, which, according to the assumptions Active Ageing Program, enable the maintenance of an active way of life, with important implications for health, wellness and quality of life in old age

Made available in DSpace on 2014-12-17T15:07:03Z (GMT). No. of bitstreams: 1 RisoleideRFO.pdf: 3036866 bytes, checksum: 745f79c8ec0d80d0135733ca196aada4 (MD5) Previous issue date: 2007-11-12 / This research deals with the activity of text revision. It aims at understanding the work of the text reviewer, taking into consideration the professional experiences of the subjects who work in the area. It s theoretical basis comes from Bakhtin Circle, mainly the concept of verbal interaction formulated from reflections on language used in different spheres of human activities, which implies the notions of discourse genres, alterity, as well as exotopy. The methodology follows the tradition of the qualitative and interpretative research. The data is composed of the statements of text reviewers both in handbooks and interviews, as well as of the description of the researcher s own experience as text reviewer. The results indicate that the revision activity needs to be orientated by a dialogical conception of language, which takes into consideration the interaction between the reviewer and the author, aiming the text finalization / Pesquisa sobre a atividade de revis?o de textos escritos com o prop?sito de compreender o trabalho do revisor, considerando para tanto as experi?ncias profissionais de sujeitos atuantes na ?rea. O estudo toma como fundamenta??o te?rica o conceito de intera??o socioverbal do C?rculo de Bakhtin, constru?do a partir de reflex?es acerca da linguagem utilizada em diversas esferas da atividade humana, o que implica as no??es de g?neros do discurso, alteridade, exotopia. A metodologia ? de natureza qualitativa e interpretativa, tendo sido os dados constitu?dos a partir dos dizeres de profissionais em manuais e entrevistas, al?m do relato de experi?ncia da pesquisadora no papel de revisora. A an?lise dos dados indica a necessidade de a atividade de revis?o ser subsidiada por uma concep??o diat?gica de linguagem e pela intera??o socioverbal entre revisor e autor, visando ao acabamento do texto

Made available in DSpace on 2014-12-17T15:08:36Z (GMT). No. of bitstreams: 1 MonicaAA_DISSERT.pdf: 1247194 bytes, checksum: cb1c306d6bf5eee4c0adef1c03fda223 (MD5) Previous issue date: 2014-04-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior / The radio is just not seen as conveying information, but a media able to establish ways that generate certain direction. We see an inclusion of the listener in the construction of programs, is exposing their life stories, commenting on facts, answering questions, choosing subjects and participating in some form of radio programming. This insertion of the listener in radio programs is generally thought of as a constituent element of the message. This study aims to analyze the participation of the listener and the forms of interaction in the " Debates of the People" that thirty- past two years is the schedule for CBN Fortaleza. The investigation was conducted through observation in studio, interview, transcription, content analysis and association analysis. This is a qualitative and quantitative research while. We found that the listeners of the program had no acceptance of interactive tools such as the Internet and social networks to make their holdings. In clipping analyzed, we noted that the participation of the listener was selected according to their relationship and proximity to the topic discussed. Also detected that the opinion is superior to the listener questions on the topic. The presenter has the function to put the questions in the listener program. Among the public comments are questions and opinions on the subject and speaks of the debaters. Among the authors, use Barbosa (2009 ), Ferraretto (2007 ), Lopez (2010 ), Ortriwano (2001 ), Peruzzo (2004 ), Prata (2009 ), Primo (2006 ), Thompson (2009 ), among others / O R?dio n?o ? considerado apenas como transmissor de informa??o, mas uma m?dia capaz de estabelecer formas que geram determinado sentido. Percebemos uma inclus?o do ouvinte na constru??o dos programas, seja expondo suas hist?rias de vida, comentando fatos, tirando d?vidas, escolhendo temas e participando de alguma forma da programa??o radiof?nica. Essa inser??o do ouvinte nos programas de r?dio geralmente ? pensada como um elemento constituinte da mensagem. Este trabalho tem como objetivo, analisar a participa??o do ouvinte e as formas de intera??o no programa Debates do Povo que h? trinta e dois anos est? na programa??o da CBN Fortaleza. A investiga??o foi realizada atrav?s da observa??o no est?dio, entrevista, transcri??o, an?lise de conte?do e an?lise associativa. Trata-se de uma pesquisa qualitativa e quantitativa ao mesmo tempo. Identificamos que os ouvintes do programa n?o tiveram aceita??o de ferramentas interativas como a Internet e as redes sociais para realizar suas participa??es. No recorte analisado, notamos que a participa??o do ouvinte foi selecionada de acordo com sua rela??o e proximidade com o tema debatido. Detectamos ainda que a opini?o ? superior ?s perguntas do ouvinte sobre o tema. O apresentador tem a fun??o de inserir as quest?es do ouvinte no programa. Entre os coment?rios do p?blico est?o perguntas e opini?es a respeito do tema e da fala dos debatedores. Entre os autores, utilizamos Barbosa (2009), Ferraretto (2007), Lopez (2010), Ortriwano (2001), Peruzzo (2004), Prata (2009), Primo (2006), Thompson (2009), entre outros

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-09-05T19:48:03Z No. of bitstreams: 1 AllysonDarlanMoreiraDaSilva_DISSERT.pdf: 10151264 bytes, checksum: c83ebd78212aba5ac16cd9b578d524b6 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-09-15T21:50:58Z (GMT) No. of bitstreams: 1 AllysonDarlanMoreiraDaSilva_DISSERT.pdf: 10151264 bytes, checksum: c83ebd78212aba5ac16cd9b578d524b6 (MD5) / Made available in DSpace on 2017-09-15T21:50:58Z (GMT). No. of bitstreams: 1 AllysonDarlanMoreiraDaSilva_DISSERT.pdf: 10151264 bytes, checksum: c83ebd78212aba5ac16cd9b578d524b6 (MD5) Previous issue date: 2017-06-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / O presente trabalho busca investigar como o corpo sujeito ? constru?do enquanto objeto sexual, desejante e desejado, de consumo no site de relacionamentos sexuais com usos de webcam, denominado C?mera Priv?, tensionando a respeito das potencialidades do corpo p?s-moderno em contexto de virtualiza??o do sexo entre duas ou mais pessoas em intera??o no ciberespa?o. Considerando a virtualiza??o da intera??o social como uma consequ?ncia da midiatiza??o, o corpo na sociedade atual encontra no avan?o tecnol?gico, que alcan?a n?veis de profundas mudan?as sociais e econ?micas, novas possibilidades de experi?ncias sexuais entre os sujeitos, motivadas, entre outras coisas, por desejos e/ou interesses financeiros. Para a realiza??o deste estudo, partimos de uma pesquisa explorat?ria interpretativa nas janelas de transmiss?es via webcam de modelos do g?nero masculino, feminino e transexual no site de relacionamento C?mera Priv?, ao longo do ano 2016 e parte de 2017, onde buscamos observar a rotina dos modelos, as estrat?gias de negocia??o destes com os clientes durante as performances sexuais no online. Estas performances se elaboram em uma composi??o de imagem e texto, integrada ao repert?rio er?tico de seus interlocutores e constru?da na rela??o individual da inter-a??o de falas, gestos e est?mulos visuais, poss?veis somente no quadro social da atualidade com a midiatiza??o. Em C?mera Priv?, percebemos como o corpo est? atrelado ao consumo a partir da virtualiza??o do desejo e das rela??es sexuais mediante transa??es comerciais entre seus usu?rios, em um mundo dominado pelo mercado de bens simb?licos. Se por um lado a sensa??o de liberdade de produ??o intelectual e audiovisual, virtualiza??o de nossas capacidades sensoriais, compartilhamento de informa??es e articula??o social no ciberespa?o na contemporaneidade t?m encorajado discursos libert?rios, a ind?stria do entretenimento, por sua vez, nos instrumentaliza em forma de rede e lan?a a sexualidade em um futuro de incertezas. / The present work seeks to investigate how the subject body is constructed as a desired and desired sexual object of consumption on the site of sexual relationships with webcam uses, called the Priv? Camera, stressing about the potentialities of the postmodern body in the context of virtualisation of the Sex between two or more people interacting in cyberspace.. Considering the virtualization of social interaction as a consequence of mediatization, the body in today's society finds in the technological advance, which reaches levels of deep social and economic changes, new possibilities of sexual experiences between the subjects, motivated among other things by desires and/or financial interests. In order to carry out this study, we started with an exploratory research on the windows of webcam transmissions of male, female and transsexual models on the C?mera Priv? relationship site, throughout 2016 and part of 2017, where we sought to observe the routine of the models, the strategies of negotiating these with clients during sexual performances in the online. These performances are elaborated in a composition of image and text, integrated to the erotic repertoire of its interlocutors and constructed in the individual relation of the inter-action of speeches, gestures and visual stimuli, possible only in the current social context with mediatization. In C?mera Priv?, we perceive how the body is linked to consumption from the virtualization of desire and sexual relations through commercial transactions among its users, in a world dominated by the market of symbolic goods. While on the one hand the sensation of freedom of intellectual and audiovisual production, virtualization of our sensorial capacities, information sharing and social articulation in contemporary cyberspace have encouraged libertarian discourses, the entertainment industry, in turn, instrumentalizes us in the form of a network And launches sexuality into a future of uncertainties.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-10-04T21:05:46Z No. of bitstreams: 1 HalineTerezaMatiasDeLimaCosta_DISSERT.pdf: 2192045 bytes, checksum: fd4867171ed1080dec47c90260404de7 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-10-11T23:11:44Z (GMT) No. of bitstreams: 1 HalineTerezaMatiasDeLimaCosta_DISSERT.pdf: 2192045 bytes, checksum: fd4867171ed1080dec47c90260404de7 (MD5) / Made available in DSpace on 2017-10-11T23:11:45Z (GMT). No. of bitstreams: 1 HalineTerezaMatiasDeLimaCosta_DISSERT.pdf: 2192045 bytes, checksum: fd4867171ed1080dec47c90260404de7 (MD5) Previous issue date: 2017-06-30 / INTRODU??O: Diversos estudos t?m mostrado que um n?mero significativo de medicamentos prescritos a pacientes pedi?tricos s?o off-label ou n?o licenciados, mas existe pouca informa??o sobre o uso destes medicamentos em unidades de terapia intensiva neonatal (UTIN), assim como estudos sobre fatores de risco para potenciais intera??es medicamento-medicamento (IMM). OBJETIVO: Identificar a prescri??o de medicamentos off-label e n?o licenciados utilizados em rec?m-nascidos (RN) hospitalizados em UTIN, al?m de avaliar frequ?ncia de IMM e seus fatores de risco. METODOLOGIA: Coorte prospectiva, no qual foram inclu?dos neonatos admitidos consecutivamente na UTIN da Maternidade Escola Janu?rio Cicco com pelo menos um medicamento prescrito e tempo de interna??o superior a 24 horas. Dados cl?nicos e farmacoterap?uticos dos neonatos foram coletados durante toda a interna??o, sendo a classifica??o dos medicamentos em off-label e n?o licenciados realizada de acordo com crit?rios da Food and Drug Administration atrav?s da base DrugDex-Micromedex?, a qual tamb?m foi utilizada na classifica??o das IMM, cujos fatores de risco foram identificados por regress?o log?stica. RESULTADOS: Entre agosto de 2015 e agosto de 2016 foram analisados 17421 itens medicamentosos em 3935 prescri??es de 220 neonatos, dos quais 96,4% foram expostos a medicamentos off-label e 66,8% a n?o licenciados. Mais de 70% dos prematuros e RN com menos de 2000g foram submetidos ? farmacoterapia com medicamentos off-label e mais de 50% aos n?o licenciados. Os anti-infecciosos para uso sist?mico foram o grupo farmacol?gico mais prescrito de forma off-label,sendo o fentanil (n=1358) e a gentamicina (n= 1197) os medicamentos com maior preval?ncia de uso off-label para RN. A cafe?na (n=1226) foi o medicamento n?o licenciado mais prescrito, seguido pelos agentes cardiovasculares (n=648) modificados pela enfermagem. Em 42,3% (n= 1665) das prescri??es foram detectadas IMM, cujos fatores de risco para IMM importantes foram o n?mero de medicamentos (OR 1,60, p<0,001), parto ces?reo (OR 2,68, p=0,06) e idade gestacional (OR 1,03, p= 0,002). CONCLUS?ES: RN em terapia intensiva ? submetido ? alta taxa de prescri??o e exposi??o a medicamentos off-label e n?o licenciados, sendo os mais frequentes os anti-infecciosos de uso sist?mico e os medicamentos atuantes no sistema nervoso, e tamb?m uma elevada incid?ncia de IMM, consistindo o n?mero de medicamentos prescritos, parto ces?reo e a idade gestacional os principais fatores de risco para IMM. / INTRODUCTION: Several studies have shown that a significant number of drugs prescribed to pediatric patients are off-label or unlicensed, but there is little information about the use of these drugs in neonatal intensive care units (NICUs), as well as studies about risk factors for drug-drug interactions (DDI). PURPOSE: To evaluate the use of off-label and unlicensed drugs in a Brazilian NICU of a teaching maternity hospital specialized in high risk pregnancy, and the frequency of DDI and associated risk factors. METHODS: A prospective cohort study was conducted between august 2015 and august 2016. All newborns admitted consecutively in the NICU of the Maternity School Janu?rio Cicco for over 24 hours and who had at least one medication prescribed were included. Demographic and clinical data were collected, as well as all medications prescribed during hospitalization. The classification of off-label and unlicensed drugs for the neonatal population according to the Food and Drug Administration criteria was done based on the DrugDex-Micromedex? database, which was also used for the classification of DDI. Logistic regression was used for the analysis of risk factors. RESULTS: A total of 17421 prescriptions items were analyzed in 3935 prescriptions of 220 newborns, of whom 96.4% were exposed to off-label medications and 66.8% to unlicensed drugs. More than 70% of premature and neonates with birth weight less than 2000g were submitted to off-label medicines and more than 50% to unlicensed. The anti-infectives for systemic use were the most prescribed off-label pharmacological group and the drugs most frequently classified as off-label for newborn were Fentanil (n= 1358) and gentamicin (n= 1197). Caffeine (n = 1226) was the most prescribed unlicensed drug, followed by cardiovascular agents (n= 648) modified by nursing. DDIs were found in 42,3% (n= 1665) of prescriptions , with number of drugs (OR 1.60, p<0,001), cesarean delivery (OR 2.68, p = 0,06) and gestational age (OR 1.03, p = 0,002) as risk factors for major DDI. CONCLUSION: Neonates in intensive care units have a high rate of prescriptions and exposure to off-label and unlicensed drugs, with antimicrobials for systemic use and drugs action on nervous system as the most frequently prescribed, as well as a high incidence of DDI, with number of medicines, cesarean delivery and gestational age being risk factors for major DDI.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-10-04T23:54:46Z No. of bitstreams: 1 BarbaraCiralliBoerner_DISSERT.pdf: 13754051 bytes, checksum: 1867ba4d0a14ecc5b81205405465f4fd (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-10-16T19:44:38Z (GMT) No. of bitstreams: 1 BarbaraCiralliBoerner_DISSERT.pdf: 13754051 bytes, checksum: 1867ba4d0a14ecc5b81205405465f4fd (MD5) / Made available in DSpace on 2017-10-16T19:44:38Z (GMT). No. of bitstreams: 1 BarbaraCiralliBoerner_DISSERT.pdf: 13754051 bytes, checksum: 1867ba4d0a14ecc5b81205405465f4fd (MD5) Previous issue date: 2017-08-18 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq) / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Vocaliza??es ultrass?nicas de ratos de freq??ncia fundamental na faixa de 30-90khz, conhecidas como usvs de '50 khz', est?o relacionadas a contextos apetitivos, como intera??es sociais, recompensa e acasalamento. No entanto, ainda n?o est? estabelecido como essas vocaliza??es contribuem para o comportamento social do rato. Dados anteriores do nosso grupo mostram que essas usvs est?o bem sincronizadas com a locomo??o do rato emissor, aumentando a possibilidade de que as vocaliza??es possam ajudar os ratos a se rastrearem no escuro. N?s testamos essa hip?tese ao avaliar como a desvocaliza??o de um ou dois ratos em pares de macho e f?mea afetaram suas intera??es espaciais durante o comportamento de acasalamento. As medidas de correla??o espacial, como dist?ncia m?dia entre os dois animais e n?mero e dura??o das persegui??es, foram analisadas para cada registro. Resultados preliminares sugerem que, embora a desvocaliza??o n?o influencie o sucesso do acasalamento, ela possa interferir especificamente nas r?pidas intera??es espaciais. / Rat ultrasonic vocalizations of fundamental frequency in the 30-90khz range known as '50 khz' usvs, are related to appetitive contexts such as social interactions, reward and mating. However, how these vocalizations contribute to rat social behaviour is not completely understood. Previous data from our lab shows that these usvs are tightly synchronized with the locomotion of the emitting rat, thus raising the possibility that vocalizations could help rats track each other in the dark. We here tested this hypothesis by assessing how devocalizing one or both rats in a male-female pair affected their spatial interactions during mating behavior. Metrics of spatial correlation, such as average distance between the two animals and number and duration of chases were analyzed for each record. Preliminary results suggest that, although devocalization does not influence success of mating, it may specifically interfere with fast spatial interactions.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-11-01T21:56:19Z No. of bitstreams: 1 ThecyusBenicioNunesDeMelo_DISSERT.pdf: 2509067 bytes, checksum: 7379b33b5f03cefaa1b0aeead7eda33c (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-11-08T22:13:02Z (GMT) No. of bitstreams: 1 ThecyusBenicioNunesDeMelo_DISSERT.pdf: 2509067 bytes, checksum: 7379b33b5f03cefaa1b0aeead7eda33c (MD5) / Made available in DSpace on 2017-11-08T22:13:02Z (GMT). No. of bitstreams: 1 ThecyusBenicioNunesDeMelo_DISSERT.pdf: 2509067 bytes, checksum: 7379b33b5f03cefaa1b0aeead7eda33c (MD5) Previous issue date: 2016-07-22 / Este trabalho apresenta os aspectos estruturais e organizacionais relacionados ao desenvolvimento do processo de transfer?ncia de tecnologia no contexto universit?rio. Nesse sentido, s?o evidenciadas as formas e os mecanismos de intera??o universidade-empresa, avalia??o das barreiras e identifica??o dos fatores, motiva??es e benef?cios dos participantes. Com base nessa investiga??o, o estudo tem como objetivo geral avaliar as barreiras existentes nos projetos acad?micos direcionados ? transfer?ncia de tecnologia, identificando vari?veis cr?ticas e propondo melhorias ao processo. A pesquisa foi desenvolvida com a utiliza??o de um estudo de caso que contemplou como amostra a Universidade Federal do Rio Grande do Norte. No procedimento metodol?gico de avalia??o das barreiras foi utilizado como ferramenta a escala de Likert e a t?cnica de An?lise de Componentes Principais (ACP). A amostra da pesquisa consistiu em 36 projetos acad?micos de 2013 a 2015, selecionados de forma aleat?ria para aplica??o de question?rio. O question?rio foi dividido em duas etapas: a primeira etapa cont?m 9 quest?es que procuram conhecer o perfil do coordenador, j? a segunda etapa contou com 30 afirma??es sobre as barreiras relacionadas ao processo de transfer?ncia de tecnologia para avalia??o dos entrevistados. Os resultados possibilitaram conhecer as barreiras mais cr?ticas em torno do processo de transfer?ncia de tecnologia que s?o: a burocracia institucional excessiva, a aus?ncia de cultura de comercializa??o da pesquisa, a burocracia governamental e a falta de agilidade e cumprimento dos prazos estabelecidos na elabora??o dos projetos. A partir da avalia??o das barreiras tamb?m foi poss?vel propor melhorias ao processo na UFRN como: a implementa??o de um projeto de extens?o continuo de apoio a melhorias no processo de transfer?ncia de tecnologia, disponibiliza??o de uma plataforma multiusu?rio englobando os resultados dos mecanismo de intera??o desenvolvidos na universidade, altera??es especificas em resolu??es e controles internos e defini??o de pol?tica dos ?rg?os de fomento ? inova??o na UFRN. / This paper presents the structural and organizational aspects related to the development of the technology transfer process in the university context. In this sense, it is evidenced the forms and mechanisms of interaction university-industry, evaluation of barriers and identification of factors, motivations and benefits of participating. Based on this research, the study has the general objective to evaluate existing barriers in academic projects directed to the transfer of technology, identifying critical variables and proposing improvements to the process. The research was conducted with the use of a case study, which had as sample the Federal University of Rio Grande do Norte. In the methodological procedure for the assessment of the barriers was used the scale tool Likert and Principal Component Analysis (PCA). The survey sample consisted of 36 academic projects from 2013 to 2015, randomly selected for the questionnaire. The questionnaire was divided into two stages: the first stage contains 9 questions seeking to know the coordinator of the profile, while the second step included 30 statements about the barriers related to technology transfer process for the interviews. The results made it possible to know the most critical barriers surrounding the technology transfer process, which are the excessive institutional bureaucracy, lack of search marketing culture, government bureaucracy and the lack of flexibility and meeting the deadlines set in the preparation of projects. From the assessment of the barriers was also possible to propose improvements to the process in UFRN as: the implementation of a continue extension project to support improvements in the technology transfer process, providing a multiuser platform encompassing the results of the interaction mechanism developed in university, specific changes in resolutions and internal controls and policy setting of agencies for innovation in UFRN.

Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2016-03-22T22:51:01Z No. of bitstreams: 1 Disserta??o Helena Gabrielle vers?o final 2016 CD ok.pdf: 6539256 bytes, checksum: 4f1abc9b5632d67eb0336d36f6feb4db (MD5) / Made available in DSpace on 2016-03-22T22:51:01Z (GMT). No. of bitstreams: 1 Disserta??o Helena Gabrielle vers?o final 2016 CD ok.pdf: 6539256 bytes, checksum: 4f1abc9b5632d67eb0336d36f6feb4db (MD5) Previous issue date: 2015-09-22 / This research investigates, based on modern social dynamics, the construction of the concept of Technological Design Interactive Rio Etc blog, in order to broaden the conceptions of design as an image it projects, communicates and can be constantly reinterpreted through a perspective interdisciplinary, seeking to recognize design as design, purpose and intent, then, is beyond its instrumentality and representation of human action through a pencil and a sheet of paper. Among the goals, I try to identify through the web interface analysis, while visual image, as shown blog design Rio Etc by proposing a street fashion concept on the Internet. I seek to do so, to express how is the formation of a Technology Interactive Design; attentive to fashion's image as a mediating element between man and culture in the digital environment and point out the street-style as contemporary phenomenon in tribalisation of subjects inserted in the group that plans and produces photographic images to the blog (main content of posts Rio Etc) and portrays the street fashion as a lifestyle, and spread this idea over the internet through the blog tool. Based on this, the Comprehensive Sociology appears to support, in the Interdisciplinary methodology, the unfolding of man as a social being who participates in the cyberculture as a producer designs and puts them at the disposal of Internet users. In this qualitative research, we present an overview of images collected in Rio Etc blog over two years of research, focused on illustrative presentation of archived records in the blog since 2007 (rise of the Rio electronic diary), incorporating the text images that best could set the observed phenomena. I emphasize that the concept of street-style produced by Rio Etc does not include the capital in its territorial and economic diversity, but rather part of a cutout on the street fashion that moves specifically for the south of the city. / A pesquisa investiga, com base na din?mica social moderna, a constru??o do conceito de Desenho Tecnol?gico Interativo do blog Rio Etc, com a finalidade de ampliar as concep??es acerca do desenho enquanto imagem que transmite, comunica e pode ser constantemente ressignificado por meio de uma perspectiva Interdisciplinar, buscando reconhecer o desenho como projeto, prop?sito e intento, logo, est? para al?m da sua instrumentalidade e representa??o da a??o humana atrav?s de um l?pis e uma folha de papel. Entre os objetivos, procuro identificar atrav?s da an?lise da interface web, enquanto imagem visual, como se apresenta o desenho do blog Rio Etc ao propor um conceito de moda de rua na internet. Busco, para isso, expressar como se d? a forma??o de um Desenho Tecnol?gico Interativo; atento para a imagem de moda como elemento mediador entre o homem e a cultura no meio digital e aponto o street-style como fen?meno contempor?neo na tribaliza??o dos sujeitos inseridos no grupo que planeja e produz imagens fotogr?ficas para o blog (principal conte?dos das postagens do Rio Etc) e retrata a moda de rua como estilo de vida, al?m de difundir esta ideia atrav?s da internet por meio da ferramenta blog. Com base nisso, a Sociologia Compreensiva aparece para sustentar, na metodologia Interdisciplinar, os desdobramentos do homem enquanto ser social que participa da cibercultura como produtor de des?gnios e os coloca ? disposi??o dos internautas. Nesta pesquisa qualitativa, apresento um apanhado de imagens coletadas no blog Rio Etc ao longo de dois anos de pesquisa, centrada na apresenta??o ilustrativa de registros arquivados no blog desde o ano de 2007 (surgimento do di?rio eletr?nico carioca), incorporando ao texto imagens que melhor pudessem configurar os fen?menos observados. Destaco que o conceito de street-style produzido pelo Rio Etc n?o contempla a capital na sua diversidade territorial e econ?mica, mas sim, parte de um recorte sobre a moda de rua que transita especificamente pela Zona Sul da cidade.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-06-30T13:52:23Z No. of bitstreams: 1 TES_LUCAS_PORCELLO_SCHILLING_PARCIAL.pdf: 7497659 bytes, checksum: 1ccccb228b48cbfe2cd307e26ad11ee2 (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-06-30T13:52:32Z (GMT) No. of bitstreams: 1 TES_LUCAS_PORCELLO_SCHILLING_PARCIAL.pdf: 7497659 bytes, checksum: 1ccccb228b48cbfe2cd307e26ad11ee2 (MD5) / Made available in DSpace on 2017-06-30T13:52:39Z (GMT). No. of bitstreams: 1 TES_LUCAS_PORCELLO_SCHILLING_PARCIAL.pdf: 7497659 bytes, checksum: 1ccccb228b48cbfe2cd307e26ad11ee2 (MD5) Previous issue date: 2016-12-16 / The pathophysiology of Alzheimer?s disease (AD) involves several pathological mechanisms, including amyloid-? and neurofibrillary tangles deposition, white matter changes and neurodegeneration. In this tranversal study, we investigated the interaction between white matter (WM) integrity and amyloid-? deposition as a potential determinant of cerebral hypometabolism in the Alzheimer?s disease (AD) continuum. Using the Alzheimer?s Disease Neuroimaging Initiative (ADNI) database, ninety-six subjects (cognitively normal (CN), n = 27; mild cognitive impairment (MCI), n = 49; and AD, n = 20) had positron emission tomography (PET) with [18F]Fluorodeoxyglucose ([18F]FDG) and [18F]Florbetapir, and magnetic resonance imaging (MRI) with Diffusion Tensor Imaging (DTI). In the first part of the study, we identified areas of fractional anisotropy (FA) reduction in angular bundle and fornix in the AD group. Among these regions, we selected for subsequent analyses a voxel of interest (VOI) in the angular bundle bilaterally. Then, using a voxel-based interaction model we examined the association of FA in the angular bundle, amyloid-? deposition, and also the potential interaction of these variables with [18F]FDG cerebral hypometabolism. In the AD group, [18F]FDG hypometabolism in the striatum, basal and mesial temporal, orbitofrontal, precuneus, anterior and posterior cingulate cortices was associated with the interaction between increase in [18F]Florbetapir standardized uptake value ratio (SUVR) in regions of interest and reduction in angular bundle FA. No significant clusters were identified in CN and MCI subjects. The interaction model, including amyloid-? deposition and WM disconnection, supports the concept of an integrative framework of AD pathophysiology where the combination of distinct pathological processes leads to progressive brain dysfunction in important cognitive-related areas / A fisiopatologia da Doen?a de Alzheimer (DA) envolve diversos mecanismos patol?gicos, como ac?mulo de ?-amiloide e de emaranhados neurofibrilares, altera??es na subst?ncia branca e neurodegenera??o. Este trabalho consiste em um estudo transversal, cujo objetivo foi investigar os efeitos da integridade da subst?ncia branca e do dep?sito de ?-amiloide como fatores determinantes do hipometabolismo cerebral no continuum da Doen?a de Alzheimer (DA). Utilizando dados obtidos atrav?s do cons?rcio internacional Alzheimer?s Disease Neuroimaging Initiative (ADNI), foram avaliados 96 indiv?duos (27 sujeitos cognitivamente normais - CN, 49 sujeitos com comprometimento cognitivo leve ? CCL, e 20 pacientes com DA) que realizaram um protocolo completo de neuroimagem com tomografia por emiss?o de p?sitrons (PET) com [18F]Fluordeoxiglicose ([18F]FDG) e [18F]Florbetapir e resson?ncia magn?tica nuclear (RMN) com a sequ?ncia de imagem de tensor de difus?o (DTI). Na primeira parte do estudo, no grupo DA foram identificadas ?reas de redu??o da anisotropia fracionada (FA) no fasc?culo angular e f?rnix. Dentre essas regi?es, um voxel de interesse (VOI) foi bilateralmente selecionado no fasc?culo angular para as an?lises subsequentes. Ap?s, examinamos a associa??o entre a FA no fasc?culo angular bilateral, o dep?sito de ?-amiloide atrav?s do PET [18F]Florbetapir Standardized Uptake Value Ratio (SUVR) nas regi?es de interesse e a poss?vel associa??o da intera??o entre ambos no hipometabolismo cerebral avaliado atrav?s de PET [18F]FDG. No grupo DA, a magnitude do hipometabolismo cerebral no corpo estriado, c?rtex orbito-frontal, temporal basal e mesial, pr?-c?neo e c?ngulo anterior e posterior foi determinada pelo efeito sin?rgico (intera??o) entre a densidade de agregados de ?-amiloide e o grau de desintegrac?o do fasc?culo angular, obtidos via [18F]Florbetapir e FA, respectivamente. N?o foram identificados clusters estatisticamente significativos nos grupos CN e CCL. Estes resultados ap?iam o conceito de que o efeito sin?rgico, mais do que os efeitos independentes da amiloidose e da desintegra??o da subst?ncia branca, determina o hipometabolismo regional na DA. De fato, o efeito da intera??o em nosso modelo, envolvendo o dep?sito de ?-amiloide e a desconex?o da subst?ncia branca, contribui para um conceito integrativo da fisiopatologia da DA, em que a a??o combinada de diferentes processos patol?gicos potencializa a degenerac?o do c?rebro.

Submitted by Verena Pereira (verenagoncalves@uefs.br) on 2018-07-17T21:59:57Z No. of bitstreams: 1 Tese Final_ Danillo Olegario.pdf: 8604713 bytes, checksum: 2e0a9905d4de264fbbd3a8997c3babb3 (MD5) / Made available in DSpace on 2018-07-17T21:59:57Z (GMT). No. of bitstreams: 1 Tese Final_ Danillo Olegario.pdf: 8604713 bytes, checksum: 2e0a9905d4de264fbbd3a8997c3babb3 (MD5) Previous issue date: 2018-03-16 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The goals of this work were to compare and evaluate statistical methods of analysis of adaptability and stability for total protein, minerals and grain yield in cowpea lines, as well as retention of these nutrients after cooking to enable recommendation and registration of new cultivars for the Brazilian semiarid. Forty-four genotypes, distributed in two experiments of different population densities, were evaluated in seven environments, in the states of Bahia, Cear?, Pernambuco and Piau?. Initially, a comparison was made of ten statistical methods of adaptability and stability using only the production data. Spearman correlation coefficients were estimated between the methods. For the assessments of adaptability and stability of the genotypes the methods of Eberhart and Russell, Lin and Binns and the Model of main additive effects and multiplicative interaction - AMMI were applied. To evaluate the effect of cooking, 24 genotypes were used, including ten lines, five commercial cultivars and nine landraces maintained by farmers. The seed protein content was quantified through the Kjeldahl method. and the minerals by the AOAC standard procedure. The statistical analyzes for the experimental designs were performed in the SAS by the GLM procedure. The AMMI method is most suitable due to the graphical arrangement of both the genotypes and the environments and high correlation with others evaluated methods. The use of highly correlated methods is not recommended, as in the cases of Plaisted and Peterson and Wricke and the methods of Annicchiarico and Lin and Binnsthat show strong association and produce similar genotypic classifications. The use of one of them incombination with that of Eberhart and Russell or AMMI can add information to the stability analysis. Statistically significant differences in the genotype as well as in the genotype?environment interaction for minerals, proteins and grain yield were observed in all the assays. The lines presenting the highest protein contents showed the lowest grain yields, and it indicated the prominent ?phenotypic cost? of protein in overall cowpea seed production. The methods by Eberhart and Russell, Lin and Binns and AMMI showed similar results for selection of superior genotypes. For the protein content, the lines C3Q, C3M, C2S and C1J presented grain yields equal to or greater than the general mean of the experiments and average of 27% of protein. For iron and zinc contents, the line C4I and T16_2R presented grain yield equal to or greater than the general mean of the experiments, with mean values of Fe and Zn 15% higher than the values of the evaluated cultivars. For the potassium and calcium contents, the C4I and C3O strains showed grain yield equal to or greater than the general average, with K and Ca means higher than the values of the cultivars evaluated. All the lines mentioned above presented broad adaptability and good stability in the series of evaluated environments showing great potential to be released as new cultivars for the Brazilian semiarid. Cooking had a reduced effect on protein, potassium, calcium, iron and zinc contents in the cowpea beans. The CPCR3F6L17 obtained high grain yield and high levels of protein, potassium, iron and zinc, after cooking, being promising for the region studied / Os objetivos deste trabalho foram comparar e avaliar m?todos estat?sticos de an?lise de adaptabilidade e estabilidade para o teor de prote?nas totais, minerais e produ??o de gr?os em linhagens de feij?o-caupi, bem como a reten??o desses nutrientes ap?s a coc??o, para possibilitar a recomenda??o e registro de novos cultivares para o semi?rido brasileiro. Quarenta e quatro gen?tipos, distribu?dos em dois experimentos de diferentes densidades populacionais, foram avaliados em sete ambientes, nos estados da Bahia, Cear?, Pernambuco e Piau?. Inicialmente, foi realizado acompara??o de dez m?todos estat?sticos de adaptabilidade e estabilidade utilizando apenas dados de produ??o. Coeficientes de correla??o Spearman foram estimados entre os m?todos. Para as avalia??es de adaptabilidade e estabilidade dos gen?tipos aplicou-se os m?todos de Eberhart e Russell, Lin e Binns e o Modelo de efeitos aditivos principais e intera??o multiplicativa - AMMI. Para avaliar o efeito da coc??o, foram utilizados 24 gen?tipos, sendo dez linhagens, cinco cultivares comerciais e nove variedades mantidas por agricultores.A quantifica??o de prote?na total foi realizada pelo m?todo de Kjeldhal, e os minerais pelo procedimento padr?o da AOAC. As an?lises estat?sticas para os delineamentos experimentais foram efetuadas no SAS pelo procedimento GLM. O m?todo AMMI ? o mais indicado devido a disposi??o gr?fica e alta correla??o com os demais m?todos. A utiliza??o de m?todos que apresentam elevada correla??o, como os m?todos Plaisted e Peterson e Wricke, Annicchiarico e Lin e Binns, que mostram forte associa??o, e produzem classifica??es genot?picas similares, n?o ? recomendado. O uso de um deles em combina??o com o de Eberhart e Russell ou AMMI pode agregar informa??o ? an?lise de estabilidade. Foram observadas diferen?as estat?sticas significativas dos quadrados m?dios de tratamentos, dos ambientes e das intera??es ambientes x tratamentos para minerais, prote?nas e produ??o de gr?os. As linhagens que apresentaram os maiores teores de prote?na e minerais apresentaram produ??es de gr?os abaixo da m?dia geral, nos dois experimentos. Os m?todos de Eberhart e Russell, Lin e Binns e o AMMI apresentam resultados semelhantes quanto a sele??o de gen?tipos superiores. Para o teor de prote?na, As linhagens C3Q, C3M, C2S e C1J apresentaram produ??es de gr?os igual ou superior a m?dia geral dos experimentos e m?dia de 27% de prote?na. Para os teores de ferro e zinco, a linhagem C4I e T16_2R apresentou produ??o de gr?os igual ou superior a m?dia geral dos experimentos, com valores m?dios de Fe e Zn, 15% superiores aos valores dos cultivares avaliados. Para os teores de pot?ssio e c?lcio, as linhagens C4I e C3O mostraram rendimento de gr?os igual ou maior do que a m?dia geral, com m?dia de K e Ca mais elevadas do que os valores dos cultivares avaliados. Todas as linhagens citadas anteriormente apresentaram ampla adaptabilidade e boa estabilidade na s?rie de ambientes avaliados mostrando grande potencial para serem lan?ados como novos cultivares para o semi?rido brasileiro. A coc??o teve efeito reduzido nos teores de prote?na, pot?ssio, c?lcio, ferro e zinco, nos gr?os de feij?o-caupi. A linhagem CPCR3F6L17 obteve alta produtividade de gr?os e elevados teores de prote?na, pot?ssio, ferro e zinco, ap?s a coc??o, mostrando-se promissora para a regi?o estudada