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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

Periodic Inhalation of Carbon Monoxide Prior to Repeated Sprint Training – a Nuanced Way for Improving Repeated Sprint Ability

Sundqvist, Christoffer January 2022 (has links)
Background: Repeated sprint training in hypoxia has shown to be superior to training in normoxia. However, both natural and simulated altitude training are strategies that are not always accessible and expensive due to traveling or the need for advanced equipment. A possible way of simulating hypoxic conditions is to administer carbon monoxide (CO) prior to training as it has been shown to reduce the oxygen transport and delivery to the muscle similar to systemic hypoxia. It is therefore hypothesized that inhaling a small bolus of CO prior to repeated-sprint exercise will potentiate the acute physiological responses during the training, thus induce performance improvements associated with repeated sprint ability compared to placebo control. Methods: 23 endurance-trained individuals (18 men and 5 women), age 33.2 ± 6.9 years, body mass 78.3 ± 11.0 kg, height 180.7 ± 7.3 cm, performed a 3-week supervised repeated sprint exercise protocol on electromagnetically braked cycle ergometers. A repeated sprint ability test was conducted pre-and post-training intervention. Participants were randomly assigned to either inhaling CO (INCO group) or inhaling a sham gas (NOCO group). Analysis of covariance (ANCOVA) was conducted to determine statistical significance by controlling for pre-test values. Results: Periodic inhalation of CO prior to repeated sprint exercise led a medium, significant difference in mean power decrement (INCO -2.63%, NOCO 8%; p <0.05, ηp2 = 0.19) and fatigue index (INCO 0.28%, NOCO 8.2%; p <0.05, ηp2 = 0.24) compared to sham gas, despite that both groups increased in number of sprints (INCO 16.58%, NOCO 27.60%; p <0.05; ηp2 = 0.71) with no difference between groups. Conclusion: Our findings in this study showed a positive effect on an improved ability to sustain power output during repeated sprints when periodic inhalation of CO is administered. Therefore, it is suggested that periodic inhalation of CO prior to repeated sprint exercise might be a nuanced way to induce favorable physiological adaptations, thus improving performance associated with repeated sprint ability.
62

The Effects of High-Intensity Interval Training and 28 days of [Beta]-Hydroxy-[Beta]-Methybutyrate Supplementation on Measures of Aerobic Power and Metabolic Thresholds

Robinson, Edward 01 January 2014 (has links)
Purpose: To examine the effects of 28 days of β-hydroxy-β-methylbutyrate free acid (HMB) and high-intensity interval training (HIIT) on maximal oxygen consumption (VO2peak), ventilatory threshold (VT), respiratory compensation point (RCP) and time to exhaustion (Tmax) in collegeaged men and women. Methods: Healthy men and women (n=34, age and VO2peak= 22.7+3.1yr and 39.3+5.0 mL. kg-1.min-1, respectively) participated in this study. All participants completed a series of tests prior and subsequent to treatment. A maximal oxygen consumption test was performed on a cycle ergometer to assess VO2peak, Tmax, VT, and RCP. The peak power output (Ppeak), power at VT (PVT) and power at RCP (PRCP) were also recorded from this test. Twenty-six subjects completed 12 HIIT (80-120% maximal workload) exercise sessions consisting of 5-6 bouts of a 2:1 minute cycling work to rest ratio protocol over a four-week period, while eight served as controls (CTL). In double-blind fashion, the HIIT groups were assigned into either a placebo (HIIT) or 3g per day of HMB (HMB-HIIT). Body composition was measured with dual energy x-ray absorptiometry (DEXA). Outcomes were assessed by ANCOVA with posttest means adjusted for pretest differences. Results: The HMB-HIIT intervention showed significant (p & lt 0.05) gains in VO2peak, VT, and PVT versus the CTL and HIIT group. Both HIIT and HMB-HIIT treatment groups demonstrated significant (p < 0.05) improvement over CTL for Ppeak, Tmax, RCP, and PRCP with no significant difference between the treatment groups. There were no significant differences observed for any measures of body composition. An independent-samples t-test confirmed that there were no significant differences between the training volumes for the HIIT and HMB-HIIT groups. Conclusion: These findings suggest that the addition of HMB supplementation may result in greater changes in VO2peak and VT than HIIT alone. Therefore, in college-aged men and women, the use of HMB supplementation may enhance the benefits of HIIT on aerobic performance measures.
63

Acute and Residual Glycemic Control Following Six Sessions of Repeat Cycle Sprint Interval Training in Apparently Healthy, but Sedentary Men

Applegate, Megan E. January 2014 (has links)
No description available.
64

Effect of High Intensity Interval Training (HIIT) on Vascular Function and Insulin Sensitivity

Sugiura, Shinichiro January 2015 (has links)
No description available.
65

The effect of high intensity interval training on the post-exercise hypotensive response in overweight/obese young women

Bonsu , Biggie 12 1900 (has links)
Thesis (MScSportSc)--Stellenbosch University, 2013. / ENGLISH ABSTRACT: There are extensive literature on the PEH response after acute and chronic aerobic and resistance exercise, as well as a few studies on concurrent and water exercise. However, there is comparatively little evidence that high intensity interval training (HIIT) elicits similar post exercise blood pressure reductions (PEH) compared to other types of exercise. Furthermore, it is difficult to quantify the magnitude of the hypotensive response following these exercises, due to variations in exercise protocols in terms of intensity and duration. Both these training variables are considered important determinants of the magnitude and duration of the PEH response. The current study determined the magnitude of the PEH response after an acute bout and six sessions of HIIT, and the effects after two weeks of detraining in overweight/obese young women. Twenty young women (aged 21 ± 2 years) volunteered for the study. All the subjects were normotensive (SBP: 119.2 ± 5.6 mmHg and DBP: 78.8 ± 4.1 mmHg). Subjects performed six sessions of HIIT within two weeks and detrained for two weeks. SBP, DBP, MAP and HR were monitored during seated recovery after exercise for 60 min to determine the change from resting values. The overall outcome showed that an acute HIIT session resulted in a reduction of 2.9 mmHg in SBP which approached near clinical significance, while six sessions of HIIT caused a clinically significant reduction of 5.3 mmHg; this response was almost totally reversed after detraining. There were no clinically significant reductions in DBP after the acute or six sessions of HIIT (1.7 and 2.7 mmHg, respectively). However, a clinically significant hypotensive response of 3.9 mmHg was sustained after detraining following the maximal exercise capacity test. MAP also reduced by a magnitude of 2.3 and 5.6 mmHg, respectively, after the acute bout and six sessions of HIIT, and detraining values were still 2.9 mmHg lower than resting values and approached near clinical significance. The results indicate that both an acute bout and six sessions of HIIT elicited a meaningful PEH response. However, the six sessions of HIIT caused a clinically significant reduction which was approximately twice the acute session. Likewise, detraining showed clinically significant effects in DBP and MAP, but SBP returned to near baseline values. This suggests that in only two weeks, the accumulated effects of six sessions of HIIT elicited a greater hypotensive response than after an acute session of HIIT. / AFRIKAANSE OPSOMMING: Daar is omvattende literatuur oor die post-oefening hipotensie (POH) na afloop van akute en kroniese aërobiese en weerstandsoefeninge, asook enkele studies oor gelyktydige krag- en uithouvermoë- en wateroefeninge. Daar is egter relatief min bewyse dat hoë intensiteit interval oefening (HIIO) soortgelyke post-oefening afnames in bloeddruk (POH) in vergelyking met ander tipes oefening veroorsaak. Voorts is dit moeilik om die omvang van die hipotensiewe respons na afloop van oefening te kwantifiseer, hoofsaaklik as gevolg van die variasies in oefeningprotokolle in terme van intensiteit en tydsduur. Beide hierdie inoefeningveranderlikes word as belangrike determinante van die omvang en die tydsduur van die POH respons beskou. Die huidige studie het die omvang van die POH respons na ʼn akute sessie en ses sessies HIIO, en die gevolge na afloop van twee weke se nie-inoefening (“detraining”) by oorgewig/vetsugtige jong dames, bepaal. Twintig jong dames (ouderdom 21 ± 2 jaar) het vrywillig ingestem om aan die studie deel te neem. Al die deelnemers was normotensief (SBD: 119.2 ± 5.6 mmHg en DBD: 78.8 ± 4.1 mmHg). Die deelnemers het ses sessies HIIO binne twee weke voltooi en het daarna vir twee weke geen inoefeningsessies gehad nie. SBD, DBD, GAD en HS is tydens ʼn sittende herstelfase vir 60 minute gemonitor om die verandering vanaf rustende waardes te bepaal. Die algehele uitkoms toon dat ʼn akute HIIO sessie ʼn afname van 2.9 mmHg in SBD tot gevolg gehad het wat aan kliniese betekenisvolheid grens, terwyl ses sessies van HIIO ʼn klinies betekenisvolle afname van 5.3 mmHg veroorsaak het; hierdie respons wat bykans volledige omgekeerd na die twee weke met geen inoefening. DBD het geen kliniese betekenisvolle afname na afloop van die akute of ses sessies van HIIO getoon nie (1.7 en 2.7 mmHg, respektiewelik). ʼn Klinies betekenisvolle hipotensiewe respons van 3.9 mmHg is egter gevind na die geen inoefeningsperiodes. GAD het ook met ʼn omvang van 2.3 en 5.6 mmHg, respektiewelik, verminder na afloop van die akute sessie en ses sessies van HIIO. Die geen inoefening waardes was steeds 2.9 mmHg laer as die rustende waardes en het aan kliniese betekenisvolheid gegrens. Die resultate toon dat beide ʼn akute sessie en ses sessies van HIIO ʼn betekenisvolle POH respons ontlok het. Ses sessies van HIIO het egter ʼn klinies betekenisvolle afname, wat ongeveer twee keer soveel as die afname van die akute sessie was, veroorsaak. In dieselde lig het ʼn twee weke geen inoefeningsperiode steeds klinies betekenisvolle veranderinge in DBD en GAD getoon, maar SBD het tot naby aan die basislyn waardes teruggekeer. Hierdie resultate suggereer dat in slegs twee weke die geakkumuleerde effekte van ses sessies van HIIO ʼn groter hipotensiewe respons as na ʼn akute sessie van HIIO ontlok het.
66

The effect of high intensity interval training and detraining on the health-related outcomes of young women

Ndlovu, Privilege B. M. 12 1900 (has links)
Thesis (MScSportSc)-- Stellenbosch University, 2013. / ENGLISH ABSTRACT: There is a growing concern in South Africa and worldwide about the global epidemic of obesity and overweightness among the general population. Obesity mediates the pathogenesis of pathological conditions and is associated with a poor quality of life, high morbidity and mortality rates and a huge burden on an individual’s and the health system’s infrastructure and finances. The answer to this rising epidemic is weight loss. Endurance training has been shown to induce weight loss however, people usually cite lack of time as a barrier to meaningful participation in exercise programmes. High intensity interval training (HIIT) therefore emerges as a potential solution to these barriers as it takes a relatively short period of time compared to endurance training. Despite the differences in exercise durations the most cogent advantage is that HIIT elicits not just similar, but even superior central and peripheral adaptations. The central and peripheral adaptations have been shown to enhance weight loss, improve blood lipids and glucose levels, as well as decreasing blood pressure. The challenge facing exercise physiologists is to find the optimal exercise intensity and duration of HIIT bouts which would be time efficient, safe and well tolerated by overweight and obese people. The shortcomings of literature are that most HIIT studies have focused on healthy, overweight and obese men and these studies cannot be extrapolated to women who have been shown to respond differently to training. Moreover, other interventions investigating the effects of HIIT in women and men have been longer term rather than short term interventions. In order to fill the gaps in the literature, the main aim of this study was to investigate the training and detraining effects of a short-term HIIT programme on selected health-related measures in young overweight and obese women. To this end, a non-random sample of 20 overweight and obese women (aged 18-25) volunteered to participate in this study. Selected health-related outcomes were measured prior to training. The pre-training testing was followed by the HIIT intervention which was two weeks and consisted of six sessions using the 10 – 15x1 minute running at 90% HRmax which was separated by one minute active recovery periods at 50-60% of HRmax. The HIIT intervention was followed by a post test in which baseline measurements were repeated. This was then followed by a two week detraining period and follow up testing. The main finding of this study was that a period of two weeks of HIIT can elicit adaptations that can lower the risk profiles of young overweight and obese women. The results showed a statistically significant decrease in body mass (1.6%, p = 0.001), fat mass (3.7%, p = 0.001) and waist circumference (4.8%, p = 0.001), and an increase in lean mass of 1.9% (p = 0.001). There was also a decrease in blood glucose (11%, p = 0.001), total cholesterol (10.4 %, p = 0.01), systolic (3.4%, p = 0.001) and diastolic blood pressure (5.8%, p = 0.001) levels. Finally there was a statistically significant increase in relative VO2max and exercise capacity after the HIIT The follow-up testing after two weeks of detraining shows that the metabolic adaptations that were achieved by the HIIT protocol are relatively lasting or are at least not completely reversed. The weight loss induced by HIIT is important in that it is the major target in lowering the prevalence of overweightness and obesity. The HIIT protocol in this study emerges as a time efficient strategy in eliciting positive adaptations in clinical populations and healthy people. Moreover these findings suggest that 10 minute and 15 minute HIIT work bouts at near-maximal intensities are possibly the minimum amount of training that is needed to induce significant weight loss and other positive health-related outcomes. / AFRIKAANSE OPSOMMING: Daar bestaan ʼn toenemende besorgdheid in Suid-Afrika en wêreldwyd oor die globale epidemie van obesiteit en oorgewig onder die algemene bevolking. Obesiteit fasiliteer die patogenese van verskeie siektetoestande en word met ʼn swak kwaliteit lewe, hoë morbiditeit en mortaliteit en ʼn geweldige las op ʼn individu en die gesondheidsowerhede se infrastruktuur en finansies geassosieer. Een van die antwoorde op hierdie stygende epidemie is gewigsverlies. Dit is reeds gewys dat uithouvermoë oefening saam met ʼn kalorie beperkende dieet gewigsverlies in die hand werk. Mense dui egter ʼn tekort aan tyd as ʼn hindernis tot betekenisvolle deelname aan ʼn oefenprogram aan. Hoë intensiteit interval inoefening (HIIO) is dus ʼn potensiële oplossing tot hierdie hindernis aangesien dit in vergelyking met uithouvermoë inoefening in ʼn relatiewe korter periode van tyd uitgevoer kan word. Afgesien van die verskille in inoefenperiodes is die mees logiese voordeel dat die HIIO nie net soortgelyke nie, maar self beter sentrale en periferale fisiologiese aanpassing voortbring. Die sentrale en periferale aanpassing verhoog gewigsverlies, verbeter bloedlipiedes en glukose vlakke, en veroorsaak ʼn afname in bloeddruk. Alhoewel ʼn aantal studies die voordele van HIIO by jonger en ouer populasies aandui, is baie min studies op vrouens uitgevoer. Bevindinge kan nie noodwendig na vrouens ekstrapoleer word nie omdat hulle dikwels verskillend op inoefening as mans reageer. Dit is ook nie bekend of ʼn kort HIIO intervensie ʼn betekenisvolle impak op oorgewig en vetsugtige vrouens sou hê nie, asook hoe blywend enige veranderinge sou wees nie. Die hoofdoel van hierdie studie was dus om die inoefening- en die geen-inoefening effekte van ʼn korttermyn HIIO program op geselekteerde gesondheidskenmerke in jong oorgewig en vetsugtige dames te bepaal. ʼn Nie-ewekansige steekproef van 20 oorgewig en vetsugtige vrouens (18-25 jaar) het vrywillig ingestem om aan hierdie studie deel te neem. Geselekteerde gesondheidskenmerke is voor die aanvang van die inoefening gemeet. Die HIIO intervensie het twee weke geduur en het uit ses sessies bestaan (10 – 15x1 minuut draf by 90% HSmaks en een minuut aktiewe herstel by 50-60% HSmaks). Die HIIO intervensie is deur ʼn na-toets gevolg waarin basislyn metings herhaal is. Dit is deur ʼn twee weke geen-inoefening periode en opvolgtoetse opgevolg. Die hoofbevinding van hierdie studie was dat ses sessies van HIIO fisiologiese aanpassings na vore gebring het wat die risiko profiele van jong oorgewig en vetsugtige vrouens verlaag het. Daar was statisties betekenisvolle afnames in liggaamsmassa (1.6%, p < 0.001), vetmassa (3.7%, p < 0.001) en heupomtrek (4.8%, p < 0.001) en ʼn toename in vetvrye liggaamsmassa van 1.9% (p < 0.001). Daar was ook ʼn afname in bloedglukose (11%, p < 0.001), totale cholesterol (10.4 %, p = 0.01), sistoliese (3.4%, p < 0.001) en diastoliese bloeddruk (5.8%, p < 0.001). Daar was ook statisties betekenisvolle verbeteringe in relatiewe VO2maks en oefeningtoleransie na inoefening. Die opvolgtoetse na twee weke van geen-inoefening het getoon dat metaboliese aanpassings wat deur die HIIO bereik is, relatief blywend van aard was of ten minste nie totaal omgekeerd was nie. Die gewigsverlies wat deur die HIIO veroorsaak was is belangrik in die sin dat dit die hoofdoelwit aanspreek om die voorkoms van oorgewig en vetsugtigheid te verminder. Die studie suggereer verder dat 10 – 15 minute HIIO werksessies, by naby maksimale intensiteite, moontlik die minimum hoeveelheid inoefening is wat benodig word om betekenisvolle gewigsverlies en ander positiewe gesondheidskenmerke te bereik.
67

Exercício resistido intervalado de alta intensidade (HIIRT) causa danos musculares e renais em indivíduos saudáveis / High intensity interval resistance training causes acute muscle and renal damage in healthy individuals

Spada, Tania de Carvalho 11 December 2017 (has links)
O treinamento resistido intervalado de alta intensidade (high intensity interval resistance training-HIIRT) tem se tornado cada vez mais popular nos últimos anos poispromoveresultados positivos com curtas sessões de treinamento. No entanto, sua alta intensidade pode causar efeitos adversos. O objetivo deste estudo foi avaliar se uma sessão de HIIRT causa dano muscular agudo e alterações nos biomarcadores de lesão renal. Cinquenta e oito voluntários saudáveis, divididos igualmente entre homens e mulheres com 24 anos de idade (mediana), participaram deste estudo. Nenhum deles usou suplementos dietéticos ou medicamentos. Eles foram submetidos a cinco minutos de aquecimento seguido de quatro minutos de HIIRT. Uma escala numérica de Borg para dor (CR10P), amostras de sangue e urina foram coletadas antes (basal), 2 e 24h após a sessão HIIRT. As amostras de sangue foram analisadas e dosadocreatinina sérica (CrS),lipocalina associada a gelatinase de neutrófilos (NGALS), creatinofosfoquinase (CPK) e mioglobina (Mio). As amostras urinárias foram analisadas e dosadoscreatinina (CrU),lipocalina associada a gelatinase de neutrófilos (NGALU), interleucina 18 (IL-18), calbindina, microalbuminúria (?albumina), trefoil factor-3(TFF3) e beta-2microglobulina (ß2M). O CR10 e CPK tiveramum aumento significativo e crescente após2 e 24h. Mioaumentou significativamente em 2h e continuouelevadaapós24h. CrSaumentou significativamente após24h e em três homens,o aumento atingiu os critérios para o diagnóstico de injúria renal aguda (IRA). Todos os biomarcadores urinários aumentaram significativamente 2 horas após o exercício e retornaram aos valores basais24h após HIIRT. Concluindo, uma única sessão de HIIRT em indivíduos jovens e saudáveis causou elevações precocese significativas em CPK, mioglobina, CrS,microalbuminúria e biomarcadores urinários, indicando lesão tubularrenal, sugerindo a ocorrência de rabdomiólise e danos funcionais eestruturais aos rins / High intensity interval resistance training (HIIRT) emerged as one of the fastest growing exercise programs in recent years because provides positive results with short training sessions. However, its high intensity might cause adverse effects. The aim of this study was to evaluate if a session of HIIRT causes acute muscle damage and changes in kidney injury biomarkers. Fifty-eight healthy volunteers, divided equally among men and women (median age 24 years), participated in this study. None of them used dietary supplements or medications. They were submitted to five minutes of warm-up followed by four minutes of HIIRT. A Borg CR10 Scale for pain (CR10P), and blood and urinary samples were collected before (baseline), 2 and 24h after HIIRT session. Blood samples were analyzed for serum creatinine (SCr), neutrophil gelatinase-associated lipocalin (SNGAL), creatine kinase(CK) and myoglobin (Myo). Urinary samples were assessed for creatinine (UCr), neutrophil gelatinase-associated lipocalin (UNGAL), interleukin 18 (IL-18), calbindin, microalbuminuria (ualbumin), trefoil factor-3 (TFF3) and beta-2 microglobulin (beta2M). CR10 had a significantly and crescent increase on 2 and 24h. CK increased significantly on 2h and further in 24h. Myo increased significantly on 2h and stayed elevated at 24h. SCr increased significantly on 24h and inthree men the increase met criteria for acute kidney injury diagnosis. All the other serum and urinary kidney injury biomarkers increased significantly at 2 hours and returned to basal values at 24h after HIIRT. In conclusion, a single session of HIIRT inyoung, healthy individuals caused early and significant elevations in CK, myoglobin, SCr, microalbuminuria and urinary biomarkers indicative of kidney tubular injury, suggesting the occurrence of rhabdomyolysis and functional and structural kidney damage
68

The Comparison of High-Intensity Interval Exercise vs. Continuous Moderate Exercise on C1q/TNF-Related Protein-9 Expression and Flow-Mediated Vasodilation

Unknown Date (has links)
The primary purpose of this study was to investigate the effect of acute high-intensity interval exercise (HIIE) vs. continuous moderate-intensity exercise (CME) on serum CTRP9 and brachial FMD responses in obese and normal-weight subjects. Sixteen participants (9 obese and 7 normal-weight) completed HIIE and CME in a randomized fashion. Our results showed a significant time effect for CTRP9 immediately following acute HIIE and CME in both groups. Furthermore, both significant treatment by time and group by time interactions for FMD were observed following both exercise protocols, with greater CME-induced FMD response in obese subjects than normal-weight subjects. Additionally, a positive correlation in percent change (baseline to peak) between CTRP9 and FMD was observed following acute CME. These findings support acute CME for improvement of endothelial function in obesity. Furthermore, the novel results from this study provide a foundation for additional examination of the mechanisms of exercise-mediated CTRP9 on endothelial function. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2017. / FAU Electronic Theses and Dissertations Collection
69

Efeitos dos treinamentos aeróbicos contínuo e intervalado na função vasomotora de ratos infartados / Effects of continuos and interval aerobic training in the vasomotor function of infarcted rats

Sousa, Luis Gustavo Oliveira de 14 December 2010 (has links)
O objetivo do presente estudo foi avaliar comparativamente os efeitos dos treinamentos físicos aeróbico contínuo (TC) e aeróbico intervalado (TI) na tolerância ao esforço e na resposta vasomotora, analisando as vias de produção de espécies reativas de oxigênio (EROs) e a biodisponibilidade de óxido nítrico (NO), em aorta torácica isolada de ratos infartados pós-ligadura da coronária esquerda (IM). As sessões de treino de ambos TC e TI foram equalizados pelo gasto calórico total, distância total percorrida e intensidade média do VO2pico. Após 48 h da última sessão de treino, os ratos foram sacrificados e feita a retirada da aorta torácica para as analises funcionais e bioquímicas. Resultados: o IM promoveu disfunção endotelial aórtica, evidenciada por um menor relaxamento à ACh e maior constrição à NE. O grupo IM-SED apresentou menor capacidade funcional (menor tolerância ao esforço e menor VO2pico). Por outro lado, ambos os grupos IM-TC e IM-TI aumentaram a vasodilatação à ACh e diminuíram a vasoconstrição à NE. Além disso, ambos os TC e TI foram eficientes em aumentar a tolerância ao esforço e VO2pico nos grupos IM. Estes efeitos benéficos do TC e TI na função endotelial aórtica estavam associados ao aumento da via de produção de NO (ativação da eNOS por maior expressão da Akt total e fosforilada) e diminuição da produção de superóxido (redução da NOX- 1), acarretando em maior biodisponibilidade de NO. Deste modo, podemos concluir que ambos os TC e TI foram igualmente efetivos em atenuar o estresse oxidativo, restaurar a função endotelial aórtica e aumentar a capacidade funcional de ratos infartados / The aim of this study was to evaluate comparatively the effects of continuous aerobic physical training (CT) and aerobic interval training (IT) on exercise tolerance and vasomotor response, analyzing the process of production of reactive oxygen species (ROS) and nitric oxide (NO) bioavailability in thoracic aorta isolated from postinfarcted rats induced by left coronary artery ligation (MI). The training sessions of both CT and IT were equalized by total caloric expenditure, total distance running and average intensity of VO2peak. 48 h after the last training session, rats were sacrificed and the thoracic aorta was removed for the functional and biochemical analysis. Results: MI caused aortic endothelial dysfunction, evidenced by a lower relaxation to ACh and increased constriction to NE. The IM-SED group had lower functional capacity (lower exercise tolerance and lower VO2peak). Moreover, both groups CT and IT increased vasodilation to ACh and reduced vasoconstriction to NE. Furthermore, both CT and IT were effective in increasing exercise tolerance and VO2peak in IM groups. These beneficial effects of CT and IT on aortic endothelial function were associated with increased NO production pathway (activation of eNOS by increased expression of total and phosphorylated Akt), and decreased superoxide production (reduction of NOX-1), resulting in increased bioavailability of NO. Thus, we conclude that both IC and IT were equally effective in attenuating oxidative stress, restore aortic endothelial function and increase the functional capacity of infarcted rats
70

Melhorias da atenção e modulação autonômica cardíaca após um programa de treinamento intervalado com esforços supra máximos de duas semanas: uma abordagem de fidelidade

Sousa, Arilson Fernandes Mendonça de 25 May 2018 (has links)
Submitted by Sara Ribeiro (sara.ribeiro@ucb.br) on 2018-08-08T14:11:40Z No. of bitstreams: 1 ArilsonFernandesMendoncadeSousaTese2018.pdf: 5768876 bytes, checksum: 66d7e7ce78b9d2a4b54e615ac9d3282d (MD5) / Approved for entry into archive by Sara Ribeiro (sara.ribeiro@ucb.br) on 2018-08-08T14:11:52Z (GMT) No. of bitstreams: 1 ArilsonFernandesMendoncadeSousaTese2018.pdf: 5768876 bytes, checksum: 66d7e7ce78b9d2a4b54e615ac9d3282d (MD5) / Made available in DSpace on 2018-08-08T14:11:52Z (GMT). No. of bitstreams: 1 ArilsonFernandesMendoncadeSousaTese2018.pdf: 5768876 bytes, checksum: 66d7e7ce78b9d2a4b54e615ac9d3282d (MD5) Previous issue date: 2018-05-25 / Only two weeks of sprint interval training (SIT) has been shown to be associated with positive changes in aerobic capacity and cardiac autonomic control. Both aerobic capacity and autonomic control have been shown to be positively associated with improved attention. However, to date, the relationship between this type of training and attention has not been investigated yet. The aim of the present study was to investigate the influence of two weeks of SIT on aerobic capacity, cardiac autonomic control and attention components in healthy university students; Also, to verify if the training fidelity would influence these adaptations. One hundred and nine participants were divided into experimental (EG) and control (CG) groups. EG performed a SIT program consisting of 6 sessions of maximal 4 × 30 s all-out efforts on a cycle ergometer, interspersed with active 4-minute rests. The criterion for fidelity was to reach> 90% of the estimated maximum heart rate (HR) during sprint sessions. After analysis, EG was divided into fidelity groups HIGH (n = 26) and LOW (n = 46), respectively. The attention components were evaluated through the Attention Network Test (ANT). The aerobic capacity (VO2max) was estimated according to Astrand's nomogram while the sum of the skinfolds: pectoral, triceps, subscapular, medial axillary, abdomen, suprailiac and thigh was verified. Autonomic HR control was assessed by HR variability (HRV) and HR complexity at rest and during ANT, before and after six sessions of SIT. Both HIGH and LOW significantly increased aerobic capacity, vagal modulation before and during ANT and executive control, and decreased body fat after SIT (p <0.05). However, only HIGH participants showed an increase in HR complexity and accuracy in ANT responses when compared to LOW (p <0.05). Two weeks of SIT improved executive control, body fat, aerobic capacity and autonomic control in university students, with better results reported for the HIGH group. / Apenas duas semanas de treinamento intervalado de esforços supra máximos (TIsm) tem mostrado estar associado com modificações positivas na capacidade aeróbia e controle autonômico cardíaco. Tanto a capacidade aeróbia, como o controlo autonômico demonstram estar associados positivamente com melhoria da atenção. Entretanto, até o presente momento a relação entre este tipo de treinamento e atenção não foi investigada. O objetivo do presente estudo foi investigar a influência de um programa de TIsm na capacidade aeróbia, controle autonômico cardíaco e componentes da atenção em jovens universitários saudáveis; ainda, verificar se a fidelidade do treinamento influenciaria essas adaptações. Cento e nove participantes foram divididos em grupo experimental (GE) e controle (GC). O GE realizou um programa TIsm que consistiu em 6 sessões de TIsm de 4 × 30 s em um cicloergômetro, intercaladas com descansos ativos de 4 min. O critério para fidelidade foi atingir> 90% da frequência cardíaca máxima estimada (FC) durante as sessões de TIsm. Após as análises, o GE foi dividido em grupos de fidelidade alta, GEA (n = 26) e baixa, GEB (n = 46), respectivamente. Os componentes da atenção foram avaliados por meio do Teste de Rede de Atenção (ANT). A capacidade aeróbia (VO2max) foi estimada segundo o nomograma de Astrand enquanto o somatório de dobras cutâneas: peitoral, tríceps, subescapular, axilar média, abdômen, supra-ilíaca e coxa foi realizada. O controle autonômico da FC foi avaliado por meio da VFC e complexidade da FC em repouso e durante o ANT, antes e depois de seis sessões de TIsm. Ambos GEA e GEB aumentaram significativamente a capacidade aeróbia, modulação vagal antes e durante a realização do ANT e o controle executivo e diminuição da gordura corporal após o TIsm (p <0,05). No entanto, apenas os participantes do GEA apresentaram um aumento na complexidade da FC e acurácia nas respostas do ANT quando comparados ao GEB (p <0,05). Duas semanas de TIsm melhoraram o controle executivo, a gordura corporal, a capacidade aeróbia e o controle autonômico em estudantes universitários, com melhores resultados relatados para o grupo com GEA fidelidade.

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