Sammanfattning: Det mest märkbara resultatet i studien är att det inte krävs en stor aktör med många följare för att påbörja en stor kampanj, men det är nödvändigt att få hjälp av dem för att nå en viral spridning. De två studerade kampanjerna hade helt olika sätt att kommunicera på, där MeToo hade en allvarsam ton och Ice Bucket Challenge ett humoristiskt och positivt laddat budskap - båda om smärtsamma ämnen. Eftersom de båda blev virala visar resultatet att det viktigaste är ett känslomässigt laddat budskap som påverkar folk, oavsett om det är glada, ilskna eller sorgsna känslor. Det krävs stark känslomässig påverkan för att personer ska känna sig motiverade att sprida vidare ett budskap. Samhällsklimatet och aktuella samhällsfrågor kan hjälpa en kampanj bli viral, men är inte nödvändig. Det finns ingen specifik riktlinje eller mall att följa för att bli viral, men det är viktigt att ha hög spridbarhet på sitt budskap och motivera mottagaren att dela vidare.

Tesis por compendio / [ES] La disponibilidad de recursos hídricos a nivel mundial ha disminuido significativamente. Entre los principales agentes que han provocado esta situación se encuentran el cambio climático, la contaminación ambiental, las actividades humanas y las fallas en las estructuras hidráulicas, entre otros. Cada vez es más complicado acceder a fuentes apropiadas que cumplan con la calidad y cantidad del recurso. A pesar de ello, la pérdida de agua debida a fugas en sistemas de distribución presurizados todavía maneja valores considerables, con pérdidas significativas a nivel mundial. Teniendo en cuenta que la necesidad de agua es cada vez mayor, se deben implementar proyectos sostenibles que permitan optimizar al máximo la disponibilidad y el uso del recurso. El objetivo principal de esta tesis es desarrollar una propuesta metodológica, que permita estimar las curvas características de las bombas que trabajan como turbinas (PATs) a partir del número específico de la máquina y en función de la velocidad de giro, desarrollando las leyes modificadas de semejanza. El cumplimiento de los objetivos de esta tesis es a través de la elaboración de tres artículos publicados, que permitieron: (i) Realizar la contextualización respecto al estado del arte en PATs con énfasis en las metodologías de obtención de la predicción del comportamiento en las mismas tales como la realización de modelos numéricos con CFDs; (ii) Proponer una nueva estrategia para desarrollar un modelo matemático para bombas que funcionan como turbinas (PATs), considerando las leyes de afinidad modificadas; (iii) Ejecutar la modelación numérica a través del paquete de código libre OpenFOAM de una bomba que trabaja como turbina y , (iv)Validar los resultados , tanto de la aplicación de las nuevas expresiones y de la modelación numérica, a través de la comparación con resultados experimentales obtenidos de los ensayos realizados a una PATs. En el Articulo 1, que corresponde a la Fase de Contextualización, se realizó una investigación en la literatura técnica sobre PATs: Características, aplicaciones y diferentes estrategias utilizadas para comprender el comportamiento del flujo. Dentro de estas estrategias, se encuentra la simulación numérica del fenómeno con paquetes CFD (Dinámica Fluido Computacional). Se analizaron 56 casos donde se estudian diferentes tipos de máquinas: axiales, mixtas y radiales bajo operación con velocidad de giro fija y velocidad de giro variable. En función de esta información se calculó el error entre la modelación numérica y los resultados experimentales; y se verificaron las principales características de las modelaciones tales como paquete CFD utilizado, modelos de cierre, tipo de mallado, etc. En el Artículo 2, que corresponde a la primera parte de la Fase del Procedimiento Analítico, se propuso un análisis con diez expresiones generales (polinómicas y exponenciales), considerando las variables más significativas. En función de este análisis se obtuvieron nuevas expresiones para obtener las curvas características de las PATs. Estas expresiones se verificaron y compararon con 15 máquinas diferentes, que se probaron variando su velocidad de rotación y su velocidad específica. En la segunda parte de la Fase del Procedimiento Analítico, se realizó una simulación numérica con el paquete CFD OpenFOAM de una PATs que ha sido ensayada en el instituto CERIS de Portugal. Por medio de los resultados experimentales se logró validar tanto las nuevas expresiones propuestas en el Artículo 2 así como la modelación numérica. En el Artículo 3 se presenta el desarrollo de esta metodología. / [CA] La disponibilitat de recursos hídrics a nivell mundial ha disminuït significativament. Entre els principals agents que han provocat aquesta situació es troben el canvi climàtic, la contaminació ambiental, les activitats humanes i les falles en les estructures hidràuliques, entre altres. Cada vegada és més complicat accedir a fonts apropiades que complisquen amb la qualitat i quantitat del recurs. Malgrat això, la pèrdua d'aigua deguda a fugides en sistemes de distribució pressuritzats encara maneja valors considerables, amb pèrdues significatives a nivell mundial. Tenint en compte que la necessitat d'aigua és cada vegada major, s'han d'implementar projectes sostenibles que permeten optimitzar al màxim la disponibilitat i l'ús del recurs. L'objectiu principal d'aquesta tesi és desenvolupar una proposta metodològica, que permeta estimar les corbes característiques de les bombes que treballen com a turbines (PATs) a partir del número específic de la màquina i en funció de la velocitat de gir, desenvolupant les lleis modificades de semblança. El compliment dels objectius d'aquesta tesi és a través de l'elaboració de tres articles publicats, que van permetre: (i) Realitzar la contextualització respecte a l'estat de l'art en PATs amb èmfasi en les metodologies d'obtenció de la predicció del comportament en les mateixes com ara la realització de models numèrics amb CFDs; (ii) Proposar una nova estratègia per a desenvolupar un model matemàtic per a bombes que funcionen com a turbines (PATs), considerant les lleis d'afinitat modificades; (iii) Executar el modelatge numèric a través del paquet de codi lliure OpenFOAM d'una bomba que treballa com a turbina i , (iv)Validar els resultats , tant de l'aplicació de les noves expressions i del modelatge numèric, a través de la comparació amb resultats experimentals obtinguts dels assajos realitzats a una PATs. En l'Articule 1 , que correspon a la Fase de Contextualització, es va realitzar una investigació en la literatura tècnica sobre PATs: Característiques, aplicacions i diferents estratègies utilitzades per a comprendre el comportament del flux. Dins d'aquestes estratègies, es troba la simulació numèrica del fenomen amb paquets CFD (Dinàmica Fluid Computacional). Es van analitzar 56 casos on s'estudien diferents tipus de màquines: axials, mixtes i radials sota operació amb velocitat de gir fixa i velocitat de gir variable. En funció d'aquesta informació es va calcular l'error entre el modelatge numèric i els resultats experimentals; i es van verificar les principals característiques. dels modelatges com ara paquet CFD utilitzat, models de tancament,tipus d'emmallat, etc. En l'Article 2, que correspon a la primera part de la Fase del Procediment Analític, es va proposar una anàlisi amb deu expressions generals (polinòmiques i exponencials), considerant les variables més significatives. En funció d'aquesta anàlisi es van obtindre noves expressions per a obtindre les corbes característiques de les PATs. Aquestes expressions es van verificar i van comparar amb 15 màquines diferents, que es van provar variant la seua velocitat de rotació i la seua velocitat específica. En la segona part de la Fase del Procediment Analític, es va realitzar una simulació numèrica amb el paquet CFD OpenFOAM d'una PATs que ha sigut assajada en l'institut CERIS de Portugal. Per mitjà dels resultats experimentals es va aconseguir validar tant les noves expressions proposades en l'Article 2 així com el modelatge numèric. En l'Article 3 es presenta el desenvolupament d'aquesta metodologia. / [EN] The availability of water resources worldwide has decreased significantly. Among the main agents that have caused this situation are climate change, environmental pollution, human activities, and failures in hydraulic structures, among others. It is becoming increasingly difficult to access appropriate sources that meet the quality and quantity of the resource. Despite this, water loss due to leaks in pressurized distribution systems still manages considerable values, with significant losses worldwide. Considering that the need for water is increasing, sustainable projects should be implemented to optimize the availability and use of the resource to the maximum. The main objective of this thesis is to develop a methodological proposal that allows estimating the characteristic curves of pumps that work as turbines (PATs) from the specific number of the machine and, depending on the rotation speed, developing the modified laws of similarity. The fulfillment of the objectives of this thesis is through the elaboration of three published articles, which allowed: (i) To carry out the contextualization regarding the state of the art in PATs with emphasis on the methodologies of obtaining the prediction of the behavior in them such as the realization of numerical models with CFDs; (ii) To propose a new strategy to develop a mathematical model for pumps that work as turbines (PATs), considering the modified affinity laws; (iii) To execute the numerical modeling through the OpenFOAM free code package of a pump that works as a turbine and, (iv) Validate the results, both of the application of the new expressions and the numerical modeling, through the comparison with experimental results obtained from the tests carried out to a PATs. In Article 1, corresponding to the Contextualization Phase, an investigation was carried out in the technical literature on PATs: Characteristics, applications, and different strategies used to understand the flow behavior. The numerical simulation of the phenomenon with CFD (Computational Fluid Dynamics) packages is found within these strategies. 56 cases were analyzed where different types of machines were studied: axial, mixed, and radial under operation with fixed rotational speed and variable rotational speed. Based on this information, the error between the numerical modeling and the experimental results was calculated; and the main characteristics of the modeling were verified, such as the CFD package used, closure models, type of meshing, etc. In Article 2, which corresponds to the first part of the Phase of the Analytical Procedure, an analysis was proposed with ten general expressions (polynomial and exponential), considering the most significant variables. Based on this analysis, new expressions were obtained to obtain the characteristic curves of the PATs. These expressions were verified and compared with 15 different machines, which were tested by varying their rotation and specific speeds. In the second part of the Analytical Procedure Phase, a numerical simulation was performed with the OpenFOAM CFD package of a PATs that has been tested at the CERIS Institute in Portugal. The experimental results made it possible to validate both the new expressions proposed in Article 2 and the numerical modeling. The development of this methodology is presented in Article 3. / Plua Aguirre, FA. (2024). Metodología de análisis para la mejora de la predicción de las curvas características de bombas trabajando como turbina operando a velocidad variable [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/203125 / Compendio

京都大学 / 新制・課程博士 / 博士(情報学) / 甲第24041号 / 情博第797号 / 新制||情||135(附属図書館) / 京都大学大学院情報学研究科システム科学専攻 / (主査)教授 加納 学, 教授 下平 英寿, 教授 石井 信 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM

Les entreprises pharmaceutiques ont progressivement adopté le concept de Process Analytical Technology (PAT) afin de contrôler et d'assurer en temps réel la qualité des produits pharmaceutiques au cours de leur production. Le PAT et un composant central du concept plus général de Quality-by-Design (QbD) promu par les agence régulatrices et visant à construire la qualité des produits via une approche scientifique et la gestion des risques.Une méthode basée sur la spectroscopie proche infrarouge (PIR) a été développée comme un outil du PAT pour contrôler en ligne la cristallisation d'un principe actif pharmaceutique. Au cours du procédé les teneurs en principe actif et en solvant résiduel doivent être déterminées avec précision afin d'atteindre un point d'ensemencement prédéfini. Une méthodologie basée sur les principes du QbD a guidé le développement et la validation de la méthode tout en assurant l'adéquation avec son utilisation prévue. Des modèles basés sur les moindres carrés partiels ont été construits à l'aide d'outils chimiométriques afin de quantifier les 2 analytes d'intérêt. La méthode a été totalement validée conformément aux requis officiels en utilisant les profils d'exactitude. Un suivi du procédé en temps réel a permis de prouver que la méthode correspond à son usage prévu.L'implémentation de cette méthode comme à l'échelle industrielle au lancement de ce nouveau procédé permettra le contrôle automatique de l'étape de cristallisation dans le but d'assurer un niveau de qualité prédéfini de l'API. D'autres avantages sont attendus incluant la réduction du temps du procédé, la suppression d'un échantillonnage difficile et d'analyses hors ligne fastidieuses. / Pharmaceutical companies are progressively adopting and introducing the Process Analytical Technology (PAT) concept to control and ensure in real-time product quality in development and manufacturing. PAT is a key component of the Quality-by-Design (QbD) framework promoted by the regulatory authorities, aiming the building of product quality based on both a strong scientific background and a quality risk management approach.An analytical method based on near infrared (NIR) spectroscopy was developed as a PAT tool to control on-line an API (active pharmaceutical ingredient) crystallization. During this process the API and residual solvent contents need to be precisely determined to reach a predefined seeding point. An original methodology based on the QbD principles was applied to conduct the development and validation of the NIR method and to ensure that it is fitted for its intended use. Partial least squares (PLS) models were developed and optimized through chemometrics tools in order to quantify the 2 analytes of interest. The method was fully validated according to the official requirements using the accuracy profile approach. Besides, a real-time process monitoring was added to the validation phase to prove and document that the method is fitted for purpose.Implementation of this method as an in-process control at industrial plant from the launch of this new pharmaceutical process will enable automatic control of the crystallization step in order to ensure a predefined quality level of the API. Other valuable benefits are expected such as reduction of the process time, and suppression of a difficult sampling and tedious off-line analyzes.

Se desarrolló cinco sistemas automatizados utilizando análisis por inyección secuencial (SIA) y análisis por inyección en flujo multijeringa (MSFIA). Se desarrolló un SI-analizador para la determinación de formaldehído utilizando la reacción de Hantzsch. El analizador fue aplicado a la monitorización en un cultivo de P. pastoris. Se desarrolló un SI-analizador para la determinación de glicerol y sorbitol. Se utilizó periodato para la reacción de Malaprade. El formaldehído generado fue cuantificado con la reacción de Hantzsch. El sistema incluyó la dilución de la muestra y procedimientos seleccionado por decisión inteligente del programa o por el usuario. Se lo aplicó a la monitorización en cultivos de P. pastoris.Se desarrolló un sistema de electroforesis capilar (CE) acoplado a un SIA aplicado a la separación de nitrofenoles. Se acopló por primera vez MSFIA con CE para pre-concentración en fase sólida y separación de nitrofenoles. Ambos sistemas mostraban recuperaciones satisfactorias para aguas ambientales. / Five analytical systems using Sequential Injection Analysis (SIA) and Multisyringe Flow Injection Analysis (MSFIA) were developed and applied with satisfactory analytical performance. A SI-analyzer for formaldehyde was developed automating Hantzsch reaction. It was successfully applied to formaldehyde monitoring in continuous medium filtrate of P. pastoris cultivation. A second SI-analyzer was developed for the determination of glycerol and sorbitol. Periodate was used as additional reagent to carry out Malaprade reaction and formaldehyde generated by polyalcohol oxidation was quantified. The system included automated sample dilution and procedures for two working ranges, selected by smart software decision or user-input. It was applied to monitoring of P. pastoris cultivations.A capillary electrophoresis (CE) system was developed and coupled to SIA. It was applied to the determination of nitrophenols. MSFIA and CE were coupled for the first time. Solid phase concentration and separation of nitrophenols were automated. The systems were applied to environmental water samples.

Drawing from observation, autoethnography, ethnographic research and audio-taped interviews, this thesis explores the complicated and emotionally charged relationship between homosexuality and Christianity. The current culture war being waged in the media between the Religious Right and members of the LGBT community often results in the isolation and rejection of those who would define themselves as gay Christians. This thesis explores the role of the Bible as it informs and catalyzes this war and other foundational beliefs used as weapons in this rhetorical conflict. Additionally, this thesis analyzes the current battle between the church and the social movement for change in light of the historical battles fought over similar movements. The rhetoric of Christianity, specifically Fundamentalist rhetoric, has been emphatically defended and then dramatically changed in every such battle. Is this a possible resolution for today’s current battle? The thesis explores the historical basis and current application of rhetorical effects on this conflict through the author’s insight as a veteran of both worlds, interviews with major players in the battle such as Randy Thomas and Kristin Tremba of Exodus International and interviews with people who step on the battlefield everyday as pastors, congregants or observers in the fight. With each interview or rhetorical analysis, the viability of dialogue between these two groups is questioned and investigated.

<p>Pat Barker’s fictional account of the Great War, The Regeneration Trilogy, completed in 1995, is considered to be her most important work to date and has captured the imagination of the reading public as well as attracting considerable scholarly attention. Although the trilogy appears to be written in the realistic style of the traditional historical novel, Barker approaches the past with certain preoccupations from 1990s Britain and rewrites the past as seen through these contemporary lenses. Consequently, the trilogy illustrates not only how the past returns to haunt the present, but also how the present reciprocally haunts perceptions of the past. The haunting quality of the trilogy is developed through an extensive, intricate pattern of intertextuality. This reciprocal haunting at times breaks the realistic framework of the narrative, giving rise to anachronisms.</p><p>This study offers a reading of trauma, class, gender and psychology as thematic areas where intertexts are activated, allowing Barker to revise and re-accentuate stories of the past. Drawing on Michel Foucault’s concept of discourse and Mikhail Bakhtin’s notion of dialogue, it focuses on the trilogy as an interactive link in an intertextual chain of communication about the Great War. Received versions of history are confirmed, expanded on and sometimes questioned. What is innovative about the trilogy is how Barker incorporates discursive formations not only from the Great War period, but from the whole twentieth century. The Great War is regenerated and transformed as it passes from one dialogic context to another. My reading shows that the trilogy presents social structures from different historical epochs through dialogism and diachronicity, making the present-day matrices of power and knowledge that continue to surround, determine and limit people’s lives highly visible. The Regeneration Trilogy regenerates the past, simultaneously confirming Barker’s claim that the historical novel can also be “a backdoor into the present”.</p>

Résumé: Lauthentification est un concept large dans lequel il sagit de pouvoir contrôler ladéquation entre le produit et les informations indiquées sur létiquette. Les techniques utilisant la spectrométrie dans le proche infrarouge dune part, et celles basées sur la PCR dautre part, permettent daborder lauthentification des produits alimentaires sous des angles totalement différents. Loriginalité de ce travail était de les associer pour résoudre deux problèmes précis : 1. lauthentification des poulets de chair à croissance lente utilisés dans des productions de qualité différenciée soumises à des cahiers des charges contraignants ; 2. la détection des farines animales dans lalimentation pour le bétail. Nos travaux sur les poulets de chair nous ont permis de développer des modèles de discrimination reposant sur les spectres dans le proche infrarouge de la viande de poulet. Ils distinguent, pour plus de 80 % des individus, les poulets issus de souches à croissance lente de ceux issus de souches à croissance rapide. Les résultats dune expérimentation animale ont également démontré que la spectrométrie dans le proche infrarouge était capable de mettre évidence des fraudes au niveau de lalimentation des animaux. Deux marqueurs moléculaires spécifiques du type de souche de poulets ont été mis en évidence et caractérisés. Pour le marqueur moléculaire caractéristique des poulets à croissance rapide, un test rapide utilisable en routine a été développé. Dans le cas de la détection des farines animales dans lalimentation du bétail, une méthode de PCR en temps réel sensible et spécifique a été mise au point participant avec succès à des études inter-laboratoires internationales. Associée dans une stratégie originale à la MPIR (microscopie dans le proche infrarouge), elle permet la détection spécifique de particules de farines de viande et dos. Summary: Authentication is a large concept focussing on the control of the correspondance between the product and the information provided on the label. Techniques based on near infrared spectroscopy on the one hand, and those based on PCR on the other hand, allow to tackle the authentication of food and feed products by different sides. The originality of this work was to associate both techniques to solve two specific problems : 1. authentication of slow growing chickens bred in high quality productions according to restricting specifications ; 2. the detection of meat and bone meals in feedingstuffs. The work on the chicken allowed us to develop discriminant models using the near infrared spectra of chicken meat. These models discriminate the chicken from slow- vs. fast-growing chicken for more than 80 % of the animals. The results of an animal experimentation also showed that near infrared spectroscopy was able to detect feeding frauds. Two molecular markers specific of the type of chicken strains were found and characterised. For the one related to the fast-growing chicken strains, a rapid assay applicable in routine testing was conceived. In the case of the meat and bone meal detection in feedingstuffs, a specific and sensitive real time PCR method was developed. It participated succesfully to international inter-laboratory studies. Its combination with NIRM (near infrared microscopy) through an original strategy allows the specific detection of meat and bone meal particles.

Pat Barker’s fictional account of the Great War, The Regeneration Trilogy, completed in 1995, is considered to be her most important work to date and has captured the imagination of the reading public as well as attracting considerable scholarly attention. Although the trilogy appears to be written in the realistic style of the traditional historical novel, Barker approaches the past with certain preoccupations from 1990s Britain and rewrites the past as seen through these contemporary lenses. Consequently, the trilogy illustrates not only how the past returns to haunt the present, but also how the present reciprocally haunts perceptions of the past. The haunting quality of the trilogy is developed through an extensive, intricate pattern of intertextuality. This reciprocal haunting at times breaks the realistic framework of the narrative, giving rise to anachronisms. This study offers a reading of trauma, class, gender and psychology as thematic areas where intertexts are activated, allowing Barker to revise and re-accentuate stories of the past. Drawing on Michel Foucault’s concept of discourse and Mikhail Bakhtin’s notion of dialogue, it focuses on the trilogy as an interactive link in an intertextual chain of communication about the Great War. Received versions of history are confirmed, expanded on and sometimes questioned. What is innovative about the trilogy is how Barker incorporates discursive formations not only from the Great War period, but from the whole twentieth century. The Great War is regenerated and transformed as it passes from one dialogic context to another. My reading shows that the trilogy presents social structures from different historical epochs through dialogism and diachronicity, making the present-day matrices of power and knowledge that continue to surround, determine and limit people’s lives highly visible. The Regeneration Trilogy regenerates the past, simultaneously confirming Barker’s claim that the historical novel can also be “a backdoor into the present”.

Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2017-06-27T13:04:09Z No. of bitstreams: 1 2010 - Alda Let?cia da Silva Santos Resende.pdf: 1570108 bytes, checksum: 847c87000cc34b478e835aa1e6f258ba (MD5) / Made available in DSpace on 2017-06-27T13:04:09Z (GMT). No. of bitstreams: 1 2010 - Alda Let?cia da Silva Santos Resende.pdf: 1570108 bytes, checksum: 847c87000cc34b478e835aa1e6f258ba (MD5) Previous issue date: 2010-06-08 / Once fish product offering by means of extractivism became stable, aquaculture emerges as a viable alternative to the increasing demand for quality protein. Brazilian low consumption of fish meat can be explained not only by cultural factors, but also by low offer of processed products as well as lack of practicity in meal preparation. In industry, after tilapia filleting, mechanically separated meat (MSM) is obtained which can be used for manufacturing of products with higher aggregated value. This work aimed at studying the technical feasibility, nutritional and sensorial qualities of tilapia fillet both in preserves and p?t? based on MSM, where protein and fatty acid profile alterations are observed. Simultaneously, a study on p?t? life span was carried out for a 180-days' period. Time x temperature binomial used (115?C x 20 minutes, and 115?C x 15 minutes, for the tilapia fillet and p?t?, respectively), were sufficent for assuring the commercial sterility of products. In relation to the preserved fillet, the most acceptable formula was of brine at 3%, and addition of fish seasoning to the covering oil, resulting in acceptance of 49%; 82%; 88%, and 65% for the attibutes: ?appearance?, ?taste?, ?texture? and for the purchasing intention, respectively. Both fatty acids EPA (Eicosapentaenoic) and DHA (docosaenoic) values were of 0.04% and 0.86%, respectively, while the sum of fatty acids series ?3 was equal to 0.34 g/100 g. Content of cholesterol was of 40.63 mg/100 g, considered low when compared to other products, such as eggs and meat. Physicalchemical composition of the product was: moisture: 76.21%; protein: 16.18%; ashes: 1.45%; ethereal extract: 3.71%. In relation to the p?t?, the storing period studied did not alter either the protein or the fatty acids profile, nor was the physical-chemical composition significantly alterated (moisture: 61.05%; protein: 9.44%; ashes: 2.41%; ethereal extract: 19.45%). By means of Quantitative Descriptive Analysis (QDA) a significant variation (P<0.05) was observed only on the averages attributed to ?spreadability? and ?creamy quality? throughout the study. Although ethereal extract in p?t? was high, cholesterol content was low (38.68 mg/100 g) taking into account that canoil oil was used in its formula, which not compromised quality of fatty acids profiled. DHA and linoleic acid values of p?t? were 0.35 and 5.60, respectively, and the sum of series ?3 fatty acids was of 1.58 g/100 g. After 180-day storing, acceptance frequency by consummers was of 95% for the ?global impression?; 91% for ?taste?; 89% for ?spreadability?, and 80% for ?appearance?. This study proves the technical, nutritional and market potential for products based on Tilapia meat. / Com a estabiliza??o da oferta de produtos de pesca pelo extrativismo, a aquicultura se mostra como alternativa vi?vel ao atendimento da demanda crescente por prote?na de qualidade. O baixo consumo brasileiro da carne de pescado pode ser explicado por fatores culturais, mas tamb?m pela baixa oferta de produtos processados e pela falta de praticidade no preparo da refei??o. Na ind?stria, ap?s o processo de filetagem da Til?pia, obt?m-se com aux?lio de m?quina despolpadeira, a carne mecanicamente separada (CMS) que pode ser utilizada na fabrica??o de produtos com maior valor agregado. Este trabalho teve como objetivo estudar a viabilidade t?cnica, qualidade nutricional e sensorial do fil? de Til?pia em conserva e do pat? ? base da CMS, observando as altera??es no perfil prot?ico e de ?cidos graxos. Foi realizado tamb?m estudo de vida ?til do pat? por per?odo de 180 dias. Os bin?mios tempo x temperatura utilizados (115?C x 20 minutos e 115?C x 15 minutos, para fil? e pat? de Til?pia, respectivamente), foram suficientes para garantir a esterilidade comercial dos produtos. Em rela??o ao fil? em conserva, a formula??o que obteve maior aceita??o foi a de salmoura a 3% e com tempero para peixe no ?leo de cobertura na qual a frequ?ncia de aceita??o do mesmo foi de 49%; 82%; 88% e 65% para os atributos ?apar?ncia?, ?sabor?, ?textura? e para a inten??o de compra, respectivamente. Os valores de ?cidos graxos EPA (eicosapentan?ico) e DHA (docosaexan?ico) foram de 0,04% e 0,86%, respectivamente e o somat?rio de ?cidos graxos da s?rie ?3 igual a 0,34 g/100 g. O teor de colesterol do produto foi de 40,63 mg/100 g sendo considerado baixo quando comparado ? outros alimentos como ovos e carnes. A composi??o f?sico-qu?mica do produto foi: umidade: 76,21%; prote?na: 16,18%; cinzas: 1,45%; extrato et?reo: 3,71%. Em rela??o ao pat?, o per?odo de armazenamento estudado n?o alterou o perfil prot?ico nem o de ?cidos graxos do produto, al?m de n?o ter alterado de forma significativa a sua composi??o f?sico-qu?mica (umidade: 61,05%; prote?na: 9,44%; cinzas: 2,41%; extrato et?reo: 19,45%). Atrav?s da An?lise Descritiva Quantitativa (ADQ) foi observada varia??o significativa (p<0,05) somente das m?dias dos atributos ?espalhabilidade? e ?cremosidade? ao longo do estudo. Apesar do teor de extrato et?reo do pat? ser elevado, o teor de colesterol foi reduzido (38,68 mg/100 g) visto que foi usado ?leo de canola na sua formula??o, o que tamb?m n?o comprometeu a qualidade do perfil de ?cidos graxos do mesmo. Os valores de DHA e ?cido linol?nico do pat? foram 0,35 e 5,60%, respectivamente e o somat?rio dos ?cidos graxos da s?rie ?3 foi de 1,58 g/100 g. Ap?s 180 dias de armazenamento, a frequ?ncia de aceita??o do pat? entre os consumidores foi de 95% para a ?impress?o global?; de 91% para o atributo ?sabor?; de 89% para a ?espalhabilidade? e de 80% para a ?apar?ncia?. Este estudo comprova o potencial t?cnico, nutricional e de mercado para os produtos ? base de carne de Til?pia.