Model-Driven Development is a development approach which is being used frequently in the automotive context in order to design models. EAST-ADL is an architectural language which models systems according to their architectural features, whereas Simulink is a tool environment which models systems according to their behavior. In this thesis work, we propose a set of transformation rules that take into consideration the EAST-ADL architectural model details and the behavioral specifications in Simulink, and generate a formal model, which can be verified UPPAAL model checker. Moreover, we implement these proposed transformation rules in a tool that automates them. The transformation rules proposed in this thesis work would be implemented for every EAST-ADL file with Simulink behavior specifications, generated by the MetaEdit+ tool. Properties like timing constraints, triggering and hierarchy in both EAST-ADL and Simulink have been considered by the transformation rules. Finally, the Brake-by-Wire case study is used to validate the tool and assess the mapping of the elements.

PURPOSE: Substantial research demonstrates that many nursing homes are not providing adequate quality of care for residents because of inadequate processes of care and insufficient numbers and training of nursing staff. Some residents experience poor-quality outcomes, such as pressure ulcers and unintended weight loss. To address these issues, the long-term care industry has focused on improving quality of care by improving staff education about care processes and reducing nurse turnover rate. The aim of this study was to compare the association between - licensed nurse hours of care and turnover rate to five quality measures—incidence of ADL decline, physical restraints, prevalence of pressure ulcers among residents with risk factors for skin breakdown, and prevalence of unintended weight loss. DESIGN: The study population included 618 freestanding Texas nursing facilities. A cross-sectional multiple regression analysis was conducted using 2007 data to examine the relationship between nurse staffing levels and turnover and resident outcomes with control variables for facility and resident characteristics. RESULTS: The high-risk pressure ulcer variable accounted for 10% of the variation in the regression model. LVN (hprd) was positively associated with an increase in high-risk pressure ulcers. The ADL decline variable accounted for 7.5% of the variation in the regression model, and RN hprd was positively associated with ADL decline. The prevalence of weight loss variable accounted for 3% of the variation in the regression model. RN turnover rate was approaching significance. The physical restraint variable accounted for 2% of the variation in the regression model. LVN contract hprd was significant and positively associated with an increase in physical restraint use although a minimal contribution to the model given the low percentage of LVN contract hprd. The prevalence of low-risk pressure ulcers was not significant. The control variable case mix index was positively associated with ADL decline, high-risk pressure ulcers, and weight loss. CONCLUSIONS: This research will contribute to understanding the relationship of licensed nursing staff to resident outcomes. Additionally, it will contribute to nursing education, research, and policy. While controlling for acuity using case mix index, some negative findings were still noted that requires further research. / text

La prise en charge à domicile des personnes âgées rend nécessaire de disposer d'un outil d'évaluation de leurs<br />autonomie. Les travaux effectués proposent une méthode globale évaluant certains critères d'autonomie jusqu'alors<br />évaluées manuellement par un médecin.<br /><br />Nous avons, dans un premier temps, développé des méthodes de détection et classification (postures, transferts,<br />marche) appliquées à des signaux accélérométriques issus d'un système embarqué. Des expérimentations ont permis<br />d'évaluer et valider les différents algorithmes sur des sujets jeunes et âgées.<br /><br />Dans un second temps, l'objectif était de combiner ces informations avec celles recueillies par d'autres capteurs<br />pouvant être présents dans l'appartement de la personne. Une méthode de fusion de données multicapteurs a été<br />élaborée et validée. Elle permet d'évaluer cinq des six critères ADL.

Diss. (sammanfattning) Linköping : Linköpings universitet, 2005. / Härtill 4 uppsatser.

Diss. (sammanfattning) Linköping :Univ., 2004. / Härtill 5 uppsatser.

This thesis explores the relationship between the needs people experience in later life and the types of care they receive. The thesis provides evidence on the role of different types of care in supporting the needs of people aged 60+ in England using the English Longitudinal Study of Ageing (ELSA). The research presented adopts a number of new approaches to capturing the multi-dimensional nature of dependency by utilising a range of binary indicators of difficulty performing 10 actions related to upper and lower body mobility, 6 activities of daily living (ADL) and 7 instrumental activities of daily living (IADL). The thesis provides a detailed analysis of the prevalence of these items when considered independently and collectively in combination. A central aim of the research is to develop a more nuanced understanding of dependency to allow for the dimensionality of the needs experienced by older people living in their own homes to be considered. The thesis utilizes a number of different approaches, including simple binary and count-based indicators of need and more complex measures reflecting dependency across different domains of need. These approaches allow a more dynamic picture of dependency in later life to be considered. Using these measures, the research explores the role of different types of care in meeting different types of need. Of these, a unique application of an existing assessment tool is presented, the Indicator of Relative Need (IoRN), which is used as a framework to derive an equivalent measure – the Array of Need (AoN). Given the aim of the study is to investigate the multi-dimensional nature of dependency, various data reduction approaches are used including principal components analysis. Finally, research from similar studies is acknowledged and work from the Survey of Health, Ageing and Retirement in Europe (SHARE) study is reproduced using ELSA. The thesis suggests that when considering the dependency needs experienced by older people living in the community, it is important to be aware that this group includes both less and more dependent older people. As such, developing a better understanding of the dynamic relationship between dependency and the receipt of informal and formal care may require more suitable measurements of dependency.

Made available in DSpace on 2016-12-06T17:06:52Z (GMT). No. of bitstreams: 1 Manuela Karloh.pdf: 2975460 bytes, checksum: 2cea2608bcb396d14a799140cc746058 (MD5) Previous issue date: 2011-11-28 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / Chronic obstructive pulmonary disease (COPD) is characterized by systemic manifestations that result in significant limitation of functional capacity and hence the individual's ability to perform activities of daily living (ADLs). Objective: to investigate the physiological response induced by the Glittre-ADL test (TGlittre) and to compare with the physiological response induced by the six-minute walk (6MWT) in patients with Chronic Obstructive Pulmonary Disease. Methods: 15 patients with COPD aged 66 ± 8 years and with forced expiratory volume in one second of 40.0 ± 18.3% predicted were evaluated. Patients underwent spirometry before and after bronchodilator, anthropometric and body composition, London Chest Activity of Daily Living scale (LCADL) and Medical Research Council (MRC). On two different days, separated by one week, two exercise protocols were performed in random order: 6MWT and TGlittre. Patients had also their physical activity in daily life (AFVD) monitored on two consecutive days. The Shapiro-Wilk test of normality was used to assess data distribution. To compare the physiological response between 6MWT and TGlittre was used the paired t test or Wilcoxon. The coefficient of Pearson or Spearman was used to verify the association between variables. The level of significance was 5%. Results: The time spent in TGlittre correlated with the distance walked on 6MWT (r= -0.82, p <0.01). Patients spent 52.9 ± 13.9% of the monitored time in sitting position, 19.6 ± 5.7% standing, 14.6 ± 12.4% lying and 12.9 ± 4.7% of the time walking The time in sitting position was correlated with both the performance in TGlittre and in 6MWT (r= 0.56 and r = -0.60, respectively, p <0.05). There were no differences between the physiological parameters measured at baseline of TGlittre and 6MWT (p>0.05). Patients achieved a VO2 of 1258.2 ± 317.8 and 1176.5 ± 364.8 ml/min at the end of TGlittre and 6MWT, respectively (p> 0.05). The VO2 showed a plateau from the third lap in TGlittre and from the third minute in 6MWT. The VO2 measured at the end of TGlittre correlated with the VO2 measured at the end of 6MWT (r= 0.85, p <0.01). All physiological variables measured at the end of TGlittre were similar and correlated with those measured at the end of 6MWT. Conclusions: TGlittre is able to induce a metabolic, respiratory and cardiovascular response similar to those induced by TC6min. / A doença pulmonar obstrutiva crônica (DPOC) caracteriza-se por manifestações sistêmicas significativas que resultam na limitação da capacidade funcional e consequentemente, na capacidade do indivíduo de realizar as suas atividades de vida diária (AVD). Objetivo: investigar a resposta fisiológica induzida pelo teste de AVD-Glittre (TGlittre) bem como comparar à induzida pelo teste de caminhada de seis minutos (TC6min) em pacientes com DPOC. Método: participaram 15 pacientes com DPOC com idade de 66 ± 8 anos e volume expiratório forçado no primeiro segundo de 40,0 ± 18,3% do previsto. Os pacientes foram submetidos à espirometria pré e pós broncodilatador, avaliação antropométrica e de composição corporal, escala London Chest Activity of Daily Living (LCADL) e Medical Research Council (MRC). Em dois dias diferentes, separados por uma semana, dois protocolos de exercício foram realizados em ordem randomizada: TC6min e TGlittre. Os pacientes realizaram ainda a monitoração das atividades físicas na vida diária (AFVD) em dois dias consecutivos. O teste de normalidade Shapiro-Wilk foi utilizado para avaliar a distribuição dos dados. Para comparar a resposta fisiológica entre o TGlittre e o TC6min foi utilizado o teste T pareado ou Wilcoxon. O coeficiente de correlação de Pearson ou Spearman foi utilizado para verificar a associação entre as variáveis. O nível de significância adotado foi de 5%. Resultados: o tempo despendido no TGlittre correlacionou-se com a distância percorrida no TC6min (r= -0,82; p<0,01). Os pacientes permaneceram 52,9 ± 13,9% do tempo monitorado na posição sentada, 19,6 ± 5,7% em pé, 14,6 ± 12,4% deitados e 12,9 ± 4,7% do tempo caminhando. O tempo sentado correlacionou-se tanto com o desempenho no TGlittre como no TC6min (r= 0,56 e r= -0,60, respectivamente; p<0,05). Não foram observadas diferenças entre os parâmetros fisiológicos basais mensurados no TGlittre e no TC6min (p>0,05). Os pacientes atingiram um VO2 de 1258,2 ± 317,8 e 1176,5 ± 364,8 ml/min ao final do TGlittre e do TC6min, respectivamente (p>0,05). O VO2 estabilizou-se a partir da terceira volta no TGlittre e do terceiro minuto no TC6min. O VO2 final do TGlittre correlacionou-se com o VO2 final do TC6min (r= 0,85; p<0,01). Todas as variáveis fisiológicas mensuradas no final do TGlittre foram similares e apresentaram correlação com as mensuradas no final do TC6min. Conclusões: o TGlittre é capaz de induzir uma resposta metabólica, ventilatória e cardiovascular similares às induzidas pelo TC6min.

Made available in DSpace on 2014-12-17T14:13:33Z (GMT). No. of bitstreams: 1 RodrigoGSV_Tese.pdf: 3463456 bytes, checksum: 9ee4f593a4e49ca7d2840717243e4e47 (MD5) Previous issue date: 2009-05-15 / Changes introduced by cardiopulmonar and neuromuscular training on basal serum insulin-like grow factor-1 (IGF-1) and cortisol levels, functional autonomy and quality of life in elderly women The aim of this study was to compare the effects of strength and aerobic training on basal serum IGF-1 and Cortisol levels, functional autonomy (FA) and quality of life (QoL) in elderly women after 12 weeks of training. The subjects were submitted the strength training (75-85% 1-RM) with weight exercises (SG; n=12; age=66.08 ? 3,37 years; BMI=26,77 ? 3,72 kg/m2), aerobic training with aquatic exercises (AG; n=13; age=68,69 ? 4,70 years; BMI=29,19 ? 2,96 kg/m2) and control group (CG; n=10; age=68,80 ? 5,41 years; BMI=29,70 ? 2,82 kg/m2). Fasting blood was analyzed to measure basal IGF-1 and cortisol levels by chemiluminescence method. The t-Student test showed increased IGF-1 in the SG (p<0.05) for intragroup comparison. The Repeated-measure ANOVA presented increased IGF-1 (p<0.05) in the SG compared to the other two groups. There were no differences in cortisol levels. All the FA tests (GDLAM autonomy protocol) presented decreased significant in the time marked in seconds to the SG. The same results were found in the AG, except in the rise from a sitting position test. The autonomy index presented significant improvements (p<0.05) in the SG related to the AG and CG and in the AG to the CG. The SG showed increased QoL (p<0.05) (by WHOQOL-Old questionnaire) in the facet 1 (sensorial functioning) and facet 5 (death and dying). Thus, the SG obtained positive changes on IGF-1 and FA levels when compared to the AG. This suggests that strength training can indicated to decrease the effects of ageing. / O objetivo do estudo foi comparar os efeitos dos treinamentos de for?a e ?bico sobre os n?veis s?ricos basais de IGF-1 e Cortisol, autonomia funcional (AF) e qualidade de vida (QV) em mulheres idosas ap?s 12 semanas de treinamento. Os sujeitos foram submetidos a um treinamento de for?a (75-85% 1-RM) na muscula??o (GF; n=12; idade=66,08 ? 3,37 anos; IMC=26,77 ? 3,72 kg/m2), treinamento aer?bico na hidrogin?stica (GA; n=13; idade=68,69 ? 4,70 anos; IMC=29,19 ? 2,96 kg/m2) e um grupo controle (GC; n=10; idade=68,80 ? 5,41 anos; IMC=29,70 ? 2,82 kg/m2). A coletada de sangue foi feita em jejum para as an?lises dos n?veis de IGF-1 e Cortisol basal (M?todo Quimioluminesc?ncia). O teste t-Student mostrou aumento do IGF-1 no GF (p<0,05) na compara??o intragrupo. A ANOVA de medidas repetidas apresentou eleva??o do IGF-1 (p<0,05) no GF comparado aos demais grupos. Os n?veis de cortisol n?o apresentaram diferen?as. Todos os testes de AF (protocolo de autonomia GDLAM) apresentaram redu??es significativas nos tempos aferidos em segundos para o GF. Os mesmos resultados foram encontrados para o GA, exceto no teste levantar da posi??o sentada. O ?ndice de autonomia apresentou melhoras significativas (p<0,05) do GF para o GA e GC e do GA para o GC. O GF apresentou aumentos significativos (p<0,05) na QV (question?rio WHOQOLOld) nas facetas 1 (habilidade sens?rio) e 5 (morte e morrer). Assim, o GF obteve melhoras significativas nos n?veis de IGF-1 e de AF quando comparado ao GA. Isto sugere que o treinamento de for?a pode ser indicado para minimizar os efeitos delet?rios do envelhecimento

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Architectural specification of real-time software systems is an activity that conveys analysis, knowledge and understanding of both the application domain and the parties involved in software construction. Architecture plays a key role in communication between stakeholders, in addition to planning the entire architectural process involved in the project. However, Architecture Description Languages (ADLs) have not been widely used in the industry. Another limiting factor for the e ff ective use of ADLs is the di ffi culty of these languages in e ff ectively expressing the architecture of complex systems. Considering this situation of di ffi culty in the e ff ective use of ADLs, the UML has been used in recent years to model the architecture. However, UML can not represent the important characteristics pertinent to real-time systems, such as security or real-time constraints. One of the advantages of the UML is the extensibility allowing the creation of profiles. In this sense, this work proposes using Systems Modeling Language (SysML), a UML profile, to model real-time systems architecture in two automotive systems, the airbag control system and the light control system. The objective of this work is to use UML and SysML to model and document the architecture and design of requirements traceability between software and systems elements, increasing the understanding of the project among the parties involved, and finally presenting SysML as a language for description of real-time software architecture. The ADL Architecture Analysis and Design Language (AADL) and SysML languages were compared to show the advantages of SysML. As a result, it was noticed that abstract features such as conditional deviations, loop, characteristics that are related to reality and consequently to the system can not be described in AADL. SysML has proved to be relevant in the context of architecture description, analysis, classification and modeling of real-time systems. The SysML Requirements diagram explicitly shows the various types of relationships between di ff erent requirements, the Block diagram enables the global view of the systems involved in a single project, the Internal Block diagram allows the internal view of the system under construction, the Activity diagram considers the behavioral view of the system. SysML concepts, articulated in the SysML Requirements, Activities, Blocks and Internal Blocks diagrams, are complementary, covering the purposes needed to describe the architecture of real-time systems. It is concluded that the proposed UML and SysML join technique provides elements to describe software requirements and their relationships with the system, to manage changes, to evolve and to trace requirements more easily, in addition to the communication being e ff ectively carried out between the stakeholders. This is important for the development of real-time systems because of the diversity of people / teams involved and influencing a wide range of design decisions. / A especificação da arquitetura de sistemas de software de tempo real é uma atividade que depreende análise, conhecimento e compreensão tanto do domínio da aplicação quanto das partes envolvidas na construção do software. A arquitetura tem um papel primordial na comunicação entre os stakeholders, além do planejamento de todo o processo arquitetural envolvido no projeto. Contudo, as Linguagens de Descrição de Arquiteturas (ADLs) não têm sido amplamente usadas na indústria. Outro fator limitador para o uso efetivo de ADLs é a dificuldade dessas linguagens em expressar efetivamente a arquitetura de sistemas complexos. Considerando essa situação de dificuldade do uso efetivo de ADLs, a UML tem sido utilizada nos últimos anos para modelagem da arquitetura. No entanto, a UML não consegue representar características importantes pertinentes a sistemas de tempo real, tais como segurança ou restrições de tempo real. Uma das vantagens da UML é a capacidade de extensão permitindo a criação de profiles. Neste sentido, este trabalho apresenta a Systems Modeling Language (SysML), um profile da UML, para modelagem da arquitetura de sistemas de tempo real em dois sistemas automotivos, o sistema de controle de airbag e o sistema de controle de faróis. Neste trabalho tem-se como objetivos utilizar a UML e a SysML para modelagem e documentação da arquitetura e delineamento de rastreabilidade de requisitos entre software e sistema, ampliando o entendimento do projeto entre as partes envolvidas, e por fim apresentar a SysML como uma linguagem para descrição da arquitetura de software de tempo real. As linguagens SysML e a ADL Architecture Analysis & Design Language (AADL) foram comparadas para mostrar as vantagens da SysML. Como resultado, foi percebido que características abstratas, tais como tomadas de decisão, repetição de uma funcionalidade (loop), características que são relacionadas a realidade e, consequentemente, ao sistema, não podem ser descritas em AADL. A SysML mostrou-se relevante no contexto da descrição, análise, classificação e modelagem de arquitetura para sistemas de tempo real. O diagrama de Requisitos da SysML mostra explicitamente os diversos tipos de relacionamentos entre diferentes requisitos, o diagrama de Blocos viabiliza a visão global dos sistemas envolvidos num único projeto, o diagrama de Blocos Internos possibilita a visão interna do sistema em construção, o diagrama de Atividades considera a visão comportamental do sistema. Os conceitos de SysML, articulados nos diagramas de Requisitos, Atividades, Blocos e Blocos Internos da SysML são complementares cobrindo os propósitos necessários para a descrição da arquitetura de sistemas de tempo real. Conclui-se que a técnica proposta da junção de UML e SysML fornece elementos para descrever requisitos de software e seus relacionamentos com o sistema, gerenciar mudanças, evoluir e rastrear requisitos mais facilmente, além da comunicação ser efetivamente realizada entre os stakeholders. Este aspecto é importante ao desenvolvimento de sistemas de tempo real, por causa da diversidade de pessoas / equipes envolvidas e que influenciam uma ampla série de decisões de projeto.

Archetypes are used to standardize a way of creating, presenting and distributing health care data. In this master thesis project the open specifications of openEHR was followed. The objective of this master thesis project has been to develop a Java based API for creating and editing openEHR archetypes. The API is a programming toolbox that can be used when developing archetype editors. Another purpose has been to implement validation functionality for archetypes. An important aspect is that the functionality of the API is well documented, this is important to ease the understanding of the system for future developers. The result was a Java based API that is a platform for future archetype editors. The API-kernel has optional immutability so developed archetypes can be locked for modification by making them immutable. The API is compatible with the openEHR specifications 1.0.1, it can load and save archetypes in ADL (Archetype Definition Language) format. There is also a validation feature that verifies that the archetype follows the right structure with respect to predefined reference models. This master thesis report also presents a basic GUI proposal.