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Childhood loss of control eating over five-year follow-upHilbert, Anja, Brauhardt, Anne 30 September 2016 (has links) (PDF)
Objective: Emerging prospective evidence from mixed samples, mostly covering short-term follow-up periods, suggests that childhood loss of control (LOC) eating predicts significant impairment in mental and physical health. This study sought to investigate the natural course of childhood LOC eating over the long term and in relation to binge eating disorder (BED) diagnosis, psychopathology, and body weight trajectory in the community.
Method: A total of 60 children (8-13 years) with LOC eating within the past three months and 60 demographically-matched children without LOC history were assessed with the Eating Disorder Examination adapted for Children and self-report questionnaires over a 5.5 year follow-up period. Missing data were imputed.
Results: Over follow-up, 38.3% of children showed persistent LOC eating, and 28.3% revealed an onset of LOC eating. Persistent LOC eating significantly predicted onset of partial-/full-syndrome BED at follow-up. Negative prognostic effects on eating disorder psychopathology, depressive symptoms, and body mass index were non-significant.
Discussion: The results indicate a moderate stability of LOC eating over the long term. LOC eating, especially if stable, was suggested as a variable risk factor of clinically relevant eating disturbances. In contrast, a prognostic value for psychopathology and body mass index was not confirmed.
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Exploring talk of causality in mothers of anorexic daughters.Blumberg, Bianca 08 February 2012 (has links)
This research focused primarily on exploring the talk of mothers of daughters with
Anorexia Nervosa, paying specific attention to their emic perceptions of the underlying
causes of Anorexia Nervosa. The research sought to reveal the discourses underpinning
participants talk. Further, the way in which these discourses serve to construct Anorexia
Nervosa in particular ways as well as the function these discourses serve were explored.
This study is qualitative and exploratory in design and provides a unique understanding
of Anorexia Nervosa in the form of emic accounts gleaned from mothers' own
experiences. The findings of this research suggest that mothers of daughters with
Anorexia Nervosa primarily reproduce a discourse on the causality of Anorexia Nervosa
that is family or biomedically focused. Through analysis of the discourses embedded in
participants’ talk, it became evident that participants reproduce discourses of gender and
femininity and are influenced by societal pressure as well as the constructions of
womanhood and motherhood. Insight into a side of the mother of the Anorectic, often
concealed in the literature, was revealed through a semi-structured interview process with
nine urban, middle-class, white South African mothers of daughters with Anorexia
Nervosa. Interviews were then transcribed and analysed according to Braun and Clarke's
thematic analysis. Incorporating the silenced voices of mothers of daughters with
Anorexia Nervosa appears to have allowed for the emergence of a more generous view of
the mother and has contributed to a larger set of discursive repertoires through which to
understand Anorexia Nervosa. This research further gave rise to the realisation of a need
for a critical education program whereby taken for granted notions can be revealed and
actively engaged. This program would ideally seek to free the anorexic woman as well as
the mother from the constraints of the uncritically constructed conceptualisations of
Anorexia Nervosa and femininity.
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"Man tränar för att bli smal" : Skolsköterskans upplevelser av det hälsofrämjande arbetet för att förebygga ätstörning / "You exercise to become slim" : The school nurse experience of health promoting work to prevent eating disorderIgelström, Maria, Åkerberg, Maria January 2019 (has links)
Bakgrund: Ätstörning bland barn och ungdomar leder till fysiskt och psykiskt lidande. Symtomen är matvägran, tvångsmässiga tankar på kost och vikt samt störd kroppsuppfattning. Trauma, grupptryck och genetiska faktorer är riskfaktorer för att insjukna och tidig upptäckt och behandling är viktigt för ett tillfrisknande. Skolsköterskans hälsofrämjande och förebyggande arbete är viktigt för att upptäcka och förhindra ätstörning. Syfte: Studiens syfte är att beskriva skolsköterskans upplevelser av det hälsofrämjande arbetet för att förebygga ätstörning. Metod: Kvalitativ metod med induktiv ansats. Semistrukturerade enskilda intervjuer samt semistrukturerade intervjuer i fokusgrupper med tio skolsköterskor analyserades enligt kvalitativ innehållsanalys. Resultat: Studien resulterade i tre huvudkategorier: salutogena möten, stödjande miljöer och känslor av otillräcklighet och frustration. Utöver detta identifierades åtta underkategorier. Konklusion: Skolsköterskans hälsofrämjande arbete för att förebygga ätstörning bygger på ett salutogent förhållningssätt. Med sin närvaro och genom samarbetet med skolpersonal och föräldrar bidrar skolsköterskan till en stödjande miljö. Skolsköterskan känner ambition och meningsfullhet men avsaknad av resurser och kompetens leder till frustration och begränsning av ett fullvärdigt hälsofrämjande arbete för att förebygga ätstörning / Background: Eating disorder among children and adolescents lead to physical and emotional suffering. Symptoms include refusing to eat, obsessive thoughts about food and weight and disturbed body image. Trauma, genetic factors and peer-pressure are risk factors and early discovery and treatment is important for recovery. The school nurse has, through health promotion and preventive work, an important role to prevent and discover eating disorder. Purpose: The aim of this study was to describe the school nurse's experiences of health promotion in school to prevent eating disorder. Method: A qualitative method with an inductive approach was used and the result was achieved using a qualitative content analysis. Semi-structured interviews and focus group interviews were conducted with ten school nurses. Result: The study resulted in three main categories; salutogenic meetings, supportive environments and feelings of inadequacy and frustration. Furthermore, eight subcategories were identified. Conclusion: The school nurse health promotion to prevent eating disorder is based on a salutogenic approach. By being present and by cooperating with school staff and parents, the school nurse contributes a supportive environment. The school nurse has ambitions for this work and finds the work meaningful, but lack of resources and competence leads to a sense of frustration and limitation of an effective health promotion to prevent eating disorder.
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Du är vad du presterar : En kritisk diskursanalys av framställningen av psykisk ohälsa hos elitidrottarer / Your performance defines who you are : A critical discourse analysis of the framing of mental illness with elite athletesDelgado Johansson, Amanda, Stahl, Tobias January 2019 (has links)
The aim of this study was to examine the depiction of mental illness with elite athletes. Mental illness has long been a sensitive object in the public's eye, but in recent years that has started to shift and the subject has destigmatized. More and more people are open and talk about their inner problems. But in one group in society the development has not been up to pace, and that is elite athletes. The study has also looked at the difference between tabloid and daily press. The theoretical framework was constructed by using the agenda setting theory, the framing theory, theories of media logic and the thoughts of news evaluation. The method used in the study was critical discourse analysis, and used in the way through out by Norman Fairclough and his three dimensional modell. A total of 38 articles from the newspapers Dagens Nyheter, Svenska dagbladet, Aftonbladet and Expressen was analyzed. The analysis found that the papers tend to portray mental illness as a negative major problem of today's society. A majority of the articles analyzed tended put the athlete aspect of the person in limelight, rather than letting the athlete just be a suffering person. They way the papers achieved to sustain the image of being a unbeatable hero by reminding the audience about the athletic achievements won, when the athlete was presented in the article. Keywords: Johan Franzén, Jenny Rissveds, mental illness, depression, concussions, concussion, eating disorder and eating disorders.
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Fatores associados ao risco para transtornos alimentares em corredores de média e longa distância / Associated factors to eating disorder risk behavior in average and long distance runners.Nishimura, Leo Massahiro Moreira 03 November 2016 (has links)
Introdução: A alteração da percepção da imagem corporal (IC) está relacionada à busca pelo considerado corpo ideal, padrão este resultado de uma construção histórica influenciada pelo meio sociocultural e também por fatores individuais. Tais fatores, aliados às exigências dos esportes de competição (como performance, adequação de peso e massa corporal), ao stress e à ansiedade consequentes, e também ao fato de que o ambiente esportivo pode ser um meio ampliador de pressões socioculturais motivadas pelo ideal de corpo magro, contribuem para que os atletas sejam uma população vulnerável à insatisfação corporal e possam constituir, consequentemente, um grupo de risco para o desenvolvimento de transtornos alimentares (TA). Considerados transtornos mentais e comportamentais, entende-se que os TA são também diretamente influenciados pela família, cujo funcionamento pode ser determinante do bem-estar e da saúde física e emocional do indivíduo. Objetivos: Investigar fatores associados ao risco para transtornos alimentares em corredores de média e longa distância adolescentes e adultos de ambos os sexos. Metodologia: Foi realizado um estudo transversal com corredores adolescentes do projeto social Kiatleta do São Paulo Futebol Clube e com corredores adultos que treinam no Campus da Cidade Universitária por meio de instrumentos que foram aplicados em sequência lógica: o questionário socioeconômico e demográfico, o Apgar Familiar, o Teste de Atitude Alimentar (Eating Attitudes Test EAT-26) e a Escala de Silhuetas de Stunkard, além da coleta de medidas antropométricas para avaliação do estado nutricional. Os resultados obtidos foram analisados de forma descritiva, comparativa e estatística a fim de correlacionar as variáveis relativas a gênero, perfil socioeconômico e demográfico dos atletas e de suas famílias, qualidade do funcionamento familiar e ocorrência de insatisfação corporal ao risco para TA. Resultados: As variáveis analisadas indicaram maior risco para TA e distorção de IC na população adulta feminina e uma parcela significativa de risco para TA e de distorção de IC em corredores adolescentes do sexo masculino. Insatisfação corporal e família disfuncional estiveram associados ao risco para TA. Conclusão: A prevenção de transtornos alimentares em corredores de média e longa distância devem considerar o atleta de forma integral, como alguém que precisa não apenas de treinamento esportivo, mas também de orientação segura sobre alimentação e de apoio familiar saudável. / Introduction: Change in the perception of body image (BI) is related to the search for the ideal body, a pattern that is the result of a historical construction influenced by sociocultural environment and personal factors. These factors, linked to demands of competitive sports (such as performance, weight and body mass adequacy), to stress, to inevitable anxiety, and also to the fact that sports atmosphere can be an amplifying way to sociocultural pressure motivated by the ideal of a thin body, contribute to the vulnerability and BI distortion of athletes and may build, consequently, an eating disorder (ED) risk group. Eating disorders are considered mental and behavioral disorders and are also directly influenced by family. A family way of functioning may determine a person\'s emotional and physical health and also her/his well-being. Objectives: the investigation of associated risk factors to eating disorders in average and long distance adolescents and adults. Methods: A cross-sectional study with adolescent runners from Kiatleta do São Paulo Futebol clube project and adult runners that train in the Campus of São Paulo University. This study applied instruments in a logical sequence: a socioeconomic and demographic questionnaire, Family Apgar, Eating Attitudes Test EAT-26, the Stunkard Silhouettes Scale and data from anthropometric measures to assess nutritional status. The results were analyzed in a descriptive, comparative and statistical way in order to see variables related to genre, social, economic and demographic profile of athletes and its families, family functioning quality and relation of the distortion in BI to predisposition of eating disorder development. Results: The variables indicated higher incidence of ED and body dissatisfaction in adult females and a significant group for ED and body dissatisfaction in adolescent male runners. Body dissatisfaction and dysfunctional family are associated to eating disorder risk. Conclusion: The prevention of eating disorders on average and long distance runners must consider the athlete as a whole, as a person that needs not only sport training, but also a healthy family support and a safe guidance for eating.
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Biomarqueurs dans deux troubles des conduites bien caractérisés : trouble des conduites alimentaires et trouble des conduites suicidaires / Biomarkers of two well-characterized conduct disorders : eating disorders and suicidal behaviorNobile, Bénédicte 04 December 2018 (has links)
Les troubles des conduites alimentaires (TCA) et les troubles des conduites suicidaires (TCS) sont des pathologies mentales graves. Ces deux troubles représentent un problème de santé publique majeur. En effet, il s’agit de pathologies pour lesquelles les pronostics sont médiocres, ayant un impact lourd sur la vie des patients et de leur entourage et représentant un coût élevé pour la société. Il n’existe actuellement aucun biomarqueur validé dans l’une ou l’autre de ces pathologies. L’objectif de ce travail est de réussir à identifier de potentiels biomarqueurs dans ces deux troubles. L’identification de biomarqueurs potentiels pourrait être utile dans divers domaines : faciliter le diagnostic des patients, améliorer la prise en charge des patients et enfin servir de cibles thérapeutiques dans le but d’élaborer de nouveaux traitements plus efficaces. Nous présenterons dans ce travail l’intérêt et l’utilisation des biomarqueurs en psychiatrie puis deux axes d’exploration des TCA ainsi qu’un axe d’exploration des TCS: l’approche neuropsychologique ainsi que l’approche biologique pour les TCA et l’approche génétique pour les TCS. Concernant les TCA, nos résultats suggèrent un intérêt potentiel des oestro-progestatifs dans l’amélioration des fonctions cognitives des patientes. Au sujet des TCS, il semblerait que deux des polymorphismes génétiques que nous avons étudiés (l’un du gène MOR et l’autre du gène SKA2) soient associés avec le risque d’émergence d’idées suicidaires au cours de l’initiation d’un traitement antidépresseur. Si ces études étaient répliquées, ces divers éléments pourraient s’avérer être des outils diagnostics et thérapeutiques. / Eating Disorders (EDs) and Suicidal Behavior (SB) are severe mental illnesses. Those two disorders represent a major public health problem. Indeed, those pathologies present a poor prognosis, induce a heavy impact on patient and their families and represant an important cost for society. There is currently no validated biomarker in one or the other disorder. The goal of this work is to successfully identify potential biomarkers in both disorders. The identification of potential biomarkers could be useful in various areas: facilitating patient’s diagnosis, improving patient management, and serving as therapeutic targets for the development of new and more effective treatments. We will present in this work the interest and the use of biomarkers in psychiatry then two axes of exploration of EDs and finally an axis of exploration of SB: the neuropsychological approach as well as the biological approach for EDs and genetic approach for SB. Regarding TCA, our results suggest a potential interest of estrogen-progestins in improving the cognitive functions of patients. With regards to SB, it appears that two of the genetic polymorphisms we studied (one from the MOR gene and the other from the SKA2 gene) are associated with the risk of suicidal ideation during the initiation of suicide an antidepressant treatment. If those studies are replicated, those elements could peep out diagnostic and therapeutic tools.
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Imagem do corpo e bulimia: a imagem da jovem bulímica e a de sua mãeEsteves, Rosita 21 December 2010 (has links)
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Previous issue date: 2010-12-21 / Nenhuma / Este estudo buscou analisar e compreender como se apresenta a imagem do corpo em jovens mulheres com bulimia em relação aos próprios ideais e aos de sua mãe. O foco do estudo centrou-se nos aspectos psíquicos referentes à constituição da imagem do corpo e suas alterações na bulimia, utilizando o referencial psicanalítico. Também foram examinadas pesquisas científicas atuais que tratam da imagem do corpo e da bulimia. A abordagem foi qualitativo-exploratória, utilizando como estratégia o procedimento de estudo de casos múltiplos. As participantes do estudo foram duas jovens do sexo feminino, com idades de 19 e 24 anos, com diagnóstico de bulimia e suas respectivas mães. O estudo de cada jovem e sua mãe foi considerado um caso. O acesso aos casos se deu através de encaminhamento por profissionais especialistas do Centro de Especialidades em Saúde (CES) - Secretária Municipal da Saúde (SMS) da Prefeitura Municipal de Caxias do Sul. Como instrumentos, foram utilizadas entrevistas não estruturadas e semiestruturadas com as jovens e com suas mães, o Desenho da Figura Humana, o EAT-26, o BITE, o BSQ e a Escala de Imagem Corporal de Stunkard. Os resultados indicaram a presença de insatisfação com a imagem do corpo tanto nas jovens bulímicas como em suas mães, gerada a partir dos próprios ideais e dos ideais maternos. Também indicaram que as jovens participantes do estudo buscaram uma imagem de corpo ideal como manifestação de falhas na constituição do narcisismo e da identidade frente à relação pouco discriminada com a figura materna. Indicaram, ainda, que as filhas, através da bulimia, estariam respondendo aos ideais conscientes e inconscientes de suas mães. / This study aimed to analyze and understand how body image is seen by young bulimic women regarding their own ideals as well as their mothers’. It focused on psychic aspects related to how body image is constituted and its alterations in bulimia, using psychoanalytical references. Recent scientific research being carried out on body image and bulimia were also examined. The approach was qualitative-exploratory, using the strategy of multiple case studies. Subjects of the study were two young women, who were 19 and 24 years old, diagnosed as bulimic, and their respective mothers. The study carried out on each young woman and her mother was considered one case. Access to the cases took place thanks to recommendations by specialized professionals from the Centro de Especialidades em Saúde (CES) - Secretaria Municipal da Saúde (SMS) (Specialized Health Center – Municipal Health Secretary) which is run by the City Hall of Caxias do Sul. Research instruments used were non-structured and semi-structured interviews with the young women and their mothers, the Human Figure Drawing Test, the EAT-26, the BITE, the BSQ, and Stunkard Body Image Scale. Results indicated that both the young bulimic women and their mothers showed dissatisfaction with their body images, from their own ideals as well as their mothers’ ideals. They also indicated that the young women taking part in the study sought for an ideal body image as manifestation of flaws in the constitution of narcissism and identity given the relationship with the mother figure not being much discriminated. In addition to that, results indicated that through bulimia, the daughters would be responding to their mothers’ conscious and unconscious ideals.
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Caracterização de pacientes com obesidade candidatos à cirurgia bariátricaLiberatore, Sabrina Fernandes 18 August 2017 (has links)
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Previous issue date: 2017-08-18 / Obesity is a chronic, multifactorial disease that involves psychological, genetic and
environmental issues. Studies have been conducted to analyze the psychological profile of the
patient who will undergo bariatric surgery. Objective: To characterize obesity patients,
candidates for bariatric surgery and to identify lifestyle and the presence of symptoms of
anxiety, depression and binge eating. Method: A retrospective study was carried out based on
data from patients' charts in a private clinic in the interior of São Paulo, who were candidates
for bariatric surgery, evaluated by psychology between January 2010 and December 2015.
The psychological evaluation included a data questionnaire (BMI), the Beck Anxiety
Inventory (BAI), the Beck Depression Inventory (BDI) and the Periodic Feed Compulsion
Scale (ECAP). Results: 188 medical records were analyzed. Age ranged from 16 to 65 years
(mean 34.7; SD: 11.3), 73% (n = 137) were female, 48.4% (n = 91) were married, and BMI
ranged from 30 to 67 (mean 42.8; dp: 6.5). The BAI results indicated that 53% (n = 100) had
minimal anxiety symptoms; of BDI that 52% (n = 97) presented symptoms of mild to severe
depression; and ECAP, that 26% (n = 50) presented binge eating. Conclusion: Most of the
patients were female, sedentary, young adults, with a history of family obesity and childhood
obesity onset. Arterial Hypertension was the most common comorbidity among participants.
Symptoms of anxiety and depression were present as well as binge eating. / Obesidade é uma doença crônica, multifatorial, que envolve questões psicológicas,
genéticas e ambientais. Estudos têm sido realizados para analisar o perfil psicológico do
paciente que será submetido à cirurgia bariátrica. Objetivo: Caracterizar pacientes com
obesidade, candidatos à cirurgia bariátrica e identificar estilo de vida e a presença de sintomas
de ansiedade, de depressão e de compulsão alimentar. Método: Estudo retrospectivo,
realizado com base em dados de prontuários de pacientes em uma clínica particular do interior
de São Paulo, candidatos à cirurgia bariátrica, avaliados pela psicologia, entre janeiro de 2010
e dezembro de 2015. A avaliação psicológica incluiu um questionário de dados pessoais, o
Índice de Massa Corporal (IMC) fornecido pelo médico, o Inventário de Ansiedade de Beck
(BAI), o Inventário de Depressão de Beck (BDI) e a Escala de Compulsão Alimentar
Periódica (ECAP). Resultados: Foram analisados 188 prontuários. A idade variou de 16 a 65
anos (média 34,7; dp: 11,3), 73% (n=137) eram do sexo feminino, 48,4% (n=91) eram
casados, e o IMC variou de 30 a 67 (média 42,8; dp: 6,5). Os resultados do BAI indicaram
que 53% (n=100) tinham sintomas mínimos de ansiedade; do BDI que 52% (n=97)
apresentaram sintomas de depressão de leve a severo; e do ECAP, que 26% (n=50)
apresentaram compulsão alimentar. Conclusão: A maioria dos pacientes era do sexo
feminino, sedentários, adultos jovens, com história de obesidade familiar e início da
obesidade na infância. Hipertensão Arterial foi a comorbidade mais encontrada entre os
participantes. Sintomas de ansiedade e depressão estiveram presentes, bem como compulsão
alimentar.
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Efeitos de um modelo de oferta e retirada de dieta de cafeteria sobre o comportamento alimentar e ansiedade em ratas / Effects of a model of cafeteria diet supply and withdrawal on eating patterns and anxiety-like behavior in female ratsRaquel Lunardi Baccetto 24 February 2017 (has links)
A incidência global de obesidade tem aumentado nas últimas décadas e o consumo excessivo de alimentos industrializados ricos em açúcar e gordura está entre suas principais causas. Pesquisas recentes têm mostrado que estes alimentos desencadeiam mecanismos neurais e comportamentos semelhantes à adicção a drogas. Sabe-se que hábitos e preferências alimentares de adultos são adquiridos na infância, mas intervenções efetivas para prevenção da obesidade e suas comorbidades em crianças e adolescentes ainda constituem um desafio para a saúde pública. O objetivo do presente estudo foi avaliar os efeitos do consumo de dieta de cafeteria e retirada desta no comportamento alimentar, peso corporal, perfil lipídico, regularidade do ciclo estral, e comportamento de ansiedade e motivação. Ratas Wistar tiveram acesso limitado a itens alimentares de consumo humano de alta densidade energética por quatro semanas, ao final das quais foi realizada a retirada da dieta experimental de duas maneiras: para um grupo total e brusca, e para outro gradual durante uma semana. Após essa retirada, que simula dietas humanas de restrição, as ratas foram submetidas a testes comportamentais para avaliar ansiedade (labirinto em cruz elevado), e motivação para restabelecimento do acesso à dieta de cafeteria (modelo de restabelecimento). O grupo submetido à dieta de cafeteria apresentou maior consumo de gorduras totais e saturadas (p<0,05), e menor consumo de proteínas totais e fibras (p<0,05). Apesar disso, o consumo energético diário entre os grupos não atingiu diferença estatisticamente significativa, assim como o peso corporal das ratas. Após retirada da dieta de cafeteria, o consumo energético foi reduzido significativamente, porém, não acompanhado de perda de peso. Houve diferença significativa no perfil lipídico, sendo que ratas do grupo Cafeteria Sem Retirada tiveram os maiores valores de colesterol total e colesterol LDL (p<0,05). As ratas que sofreram retirada da dieta de cafeteria tiveram seus valores de colesterol similares às alimentadas somente com ração. A retirada completa da dieta de cafeteria e consequente diminuição do consumo energético foi responsável por irregularidade no ciclo estral das ratas. Os resultados no labirinto em cruz elevado não atingiram diferença estatisticamente significativa. O grupo Ração passou mais tempo no lado claro (p<0,05), conforme mostrado pelo teste de restabelecimento. A oferta limitada, de curto prazo, pós-desmame da dieta de cafeteria foi efetiva no desenvolvimento de compulsão alimentar em ratas adolescentes, porém sem evidências de vício alimentar. É provável que a obesidade seja condição necessária para o vício. Esperamos que os resultados deste estudo contribuam para o conhecimento da relação entre qualidade da dieta e comportamento alimentar e de adicção em ratas adolescentes. / The global incidence of obesity has steadily risen in the last decades and the excessive intake of industrialized food rich in sugar and fat is among its main causes. Recent researches have shown that these foods activate neural mechanism and behaviors similar to what is seen with drug addiction. It is known that adults eating habits and preferences are generally established during childhood, but effective preventive measures against obesity and its comorbities in children and adolescents are still a current public health challenge. The goal of the present study was to evaluate the effects of a cafeteria diet intake and withdrawal on eating behavior, body weight, lipid profile, estrous cycle regularity, and anxiety-like and motivational behavior. Female Wistar rats had limited access to energy-dense food items typically consumed by humans for four weeks, at the end of which, withdrawal from this diet occurred in one of two ways: for a group withdrawal was abrupt and total, and for another group, gradual for one week. After withdrawal, which attempts to mimic human restrictive dieting, we evaluated rats anxiety-like behavior through the elevated plus maze, and their motivation to reinstate access to the cafeteria diet through a reinstatement model. Daily energy intake between groups did not reach significant difference, as well as their body weight. Cafeteria fed rats did gain weight at a faster pace, and had a significant greater intake of total and saturated fat, and sodium (p<0.05); and a significantly lower intake of proteins and fibers (p<0.05). Groups that underwent withdrawal reduced their caloric intake significantly, but there was no weight loss. Rats with continuous access to cafeteria diet also had higher levels of total and LDL cholesterol (p<0.05), and rats from withdrawal groups had their cholesterol levels similar to chow-only animals. The total withdrawal of the cafeteria diet and resulting lower energy intake were also responsible for estrous cycle irregularities. There was no significant difference in rats performance in the EPM test. Chow only rats spent significantly more time in an aversive setting in order to gain access to an item from the cafeteria diet (p<0.05). The limited, short term, post-weaning offer of a cafeteria diet was effective in developing compulsive eating disorder, but without signs of food addiction. It is likely that obesity is precedent to the development of addiction. We expect that the results from this project contribute to the ongoing discussion and investigation on eating and addiction behavior in female adolescents rats.
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Efeitos de um modelo de oferta e retirada de dieta de cafeteria sobre o comportamento alimentar e ansiedade em ratas / Effects of a model of cafeteria diet supply and withdrawal on eating patterns and anxiety-like behavior in female ratsBaccetto, Raquel Lunardi 24 February 2017 (has links)
A incidência global de obesidade tem aumentado nas últimas décadas e o consumo excessivo de alimentos industrializados ricos em açúcar e gordura está entre suas principais causas. Pesquisas recentes têm mostrado que estes alimentos desencadeiam mecanismos neurais e comportamentos semelhantes à adicção a drogas. Sabe-se que hábitos e preferências alimentares de adultos são adquiridos na infância, mas intervenções efetivas para prevenção da obesidade e suas comorbidades em crianças e adolescentes ainda constituem um desafio para a saúde pública. O objetivo do presente estudo foi avaliar os efeitos do consumo de dieta de cafeteria e retirada desta no comportamento alimentar, peso corporal, perfil lipídico, regularidade do ciclo estral, e comportamento de ansiedade e motivação. Ratas Wistar tiveram acesso limitado a itens alimentares de consumo humano de alta densidade energética por quatro semanas, ao final das quais foi realizada a retirada da dieta experimental de duas maneiras: para um grupo total e brusca, e para outro gradual durante uma semana. Após essa retirada, que simula dietas humanas de restrição, as ratas foram submetidas a testes comportamentais para avaliar ansiedade (labirinto em cruz elevado), e motivação para restabelecimento do acesso à dieta de cafeteria (modelo de restabelecimento). O grupo submetido à dieta de cafeteria apresentou maior consumo de gorduras totais e saturadas (p<0,05), e menor consumo de proteínas totais e fibras (p<0,05). Apesar disso, o consumo energético diário entre os grupos não atingiu diferença estatisticamente significativa, assim como o peso corporal das ratas. Após retirada da dieta de cafeteria, o consumo energético foi reduzido significativamente, porém, não acompanhado de perda de peso. Houve diferença significativa no perfil lipídico, sendo que ratas do grupo Cafeteria Sem Retirada tiveram os maiores valores de colesterol total e colesterol LDL (p<0,05). As ratas que sofreram retirada da dieta de cafeteria tiveram seus valores de colesterol similares às alimentadas somente com ração. A retirada completa da dieta de cafeteria e consequente diminuição do consumo energético foi responsável por irregularidade no ciclo estral das ratas. Os resultados no labirinto em cruz elevado não atingiram diferença estatisticamente significativa. O grupo Ração passou mais tempo no lado claro (p<0,05), conforme mostrado pelo teste de restabelecimento. A oferta limitada, de curto prazo, pós-desmame da dieta de cafeteria foi efetiva no desenvolvimento de compulsão alimentar em ratas adolescentes, porém sem evidências de vício alimentar. É provável que a obesidade seja condição necessária para o vício. Esperamos que os resultados deste estudo contribuam para o conhecimento da relação entre qualidade da dieta e comportamento alimentar e de adicção em ratas adolescentes. / The global incidence of obesity has steadily risen in the last decades and the excessive intake of industrialized food rich in sugar and fat is among its main causes. Recent researches have shown that these foods activate neural mechanism and behaviors similar to what is seen with drug addiction. It is known that adults eating habits and preferences are generally established during childhood, but effective preventive measures against obesity and its comorbities in children and adolescents are still a current public health challenge. The goal of the present study was to evaluate the effects of a cafeteria diet intake and withdrawal on eating behavior, body weight, lipid profile, estrous cycle regularity, and anxiety-like and motivational behavior. Female Wistar rats had limited access to energy-dense food items typically consumed by humans for four weeks, at the end of which, withdrawal from this diet occurred in one of two ways: for a group withdrawal was abrupt and total, and for another group, gradual for one week. After withdrawal, which attempts to mimic human restrictive dieting, we evaluated rats anxiety-like behavior through the elevated plus maze, and their motivation to reinstate access to the cafeteria diet through a reinstatement model. Daily energy intake between groups did not reach significant difference, as well as their body weight. Cafeteria fed rats did gain weight at a faster pace, and had a significant greater intake of total and saturated fat, and sodium (p<0.05); and a significantly lower intake of proteins and fibers (p<0.05). Groups that underwent withdrawal reduced their caloric intake significantly, but there was no weight loss. Rats with continuous access to cafeteria diet also had higher levels of total and LDL cholesterol (p<0.05), and rats from withdrawal groups had their cholesterol levels similar to chow-only animals. The total withdrawal of the cafeteria diet and resulting lower energy intake were also responsible for estrous cycle irregularities. There was no significant difference in rats performance in the EPM test. Chow only rats spent significantly more time in an aversive setting in order to gain access to an item from the cafeteria diet (p<0.05). The limited, short term, post-weaning offer of a cafeteria diet was effective in developing compulsive eating disorder, but without signs of food addiction. It is likely that obesity is precedent to the development of addiction. We expect that the results from this project contribute to the ongoing discussion and investigation on eating and addiction behavior in female adolescents rats.
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