Orientador: Elcio Marcantonio Junior / Banca: Izabel Yoko Ito / Banca: Roberto Fraga Moreira Lotufo / Resumo: A microbiota presente na peri-implantite induzida por ligadura, em diferentes superfícies de implantes osseointegrados, foi analisada em 6 cães adultos machos. 36 implantes osseointegrados (9 Ticp: titânio comercialmente puro; 9 TPS: titânio plasma spray; 9 HA: hidroxiapatita; 9 superfícies tratadas com ácidos) foram inseridos e distribuídos igualmente 3 meses após exodontia de todos os pré-molares inferiores. Após um período de 3 meses de osseointegração, os implantes receberam os cicatrizadores. Decorridos 45 dias de cicatrização, amostras peri-implantares foram colhida, utilizando pontas de papel, no período 0 e após a colocação de ligaduras com fio de algodão, nos períodos 20, 40 e 60 dias. A contagem total de microrganismos (CTM) e a proporação de A. actinomycetemcomitans, Bacteroides forsythus, P. gingivalis, P. intermedia, Campylobacter sp, Capnocytophaga sp., Fusobacterium sp., Peptostreptococcus micros, bastonetes anaeróbios Gram-negativos, Streptococcus beta-hemolíticos, Eikenella corrodens e Candida sp. foram analisadas. Não houve diferença da CTM entre as diferentes superfícies (p>0,05). A Pg não foi detectada no tempo 0; nos tempos 20 e 40 foi detectada em 12 implantes (4 Ticp, 4 HA, 2 TPS e 1 Sup. Trat. com ácidos) e no período 60 dias, em 9 (2 Ticp, 3 HA, 2 TPS e 1 Sup. Trat. com ácidos), tendo menor afinidade à superfície tratada com ácidos. Pi foi detectada em 5 implantes (2 Ticp, 2 HA e 1 Sup. Trat. com ácidos) no período 0 e em 100% dos implantes nos demais períodos. Fusobacterium sp. foi detectado em todos os períodos, tendo uma maior afinidade à HA. Streptococcus beta-hemolíticos foi detectado em 6 implantes (3 Ticp, 1 TPS e 2 HA) no período 0 e 30, 26 e 24 implantes respectivamente nos períodos 20, 40 e 60. Campylobacter sp. e Candida sp. foram detectadas em baixas proporções. Os demais microrganismos não... (Resumo completo, clicar acesso eletrônico abaixo). / Abstract: The microbiota associated with ligature-induced peri-implantitis, in different dental implants surfaces, was investigated by cultivation on enriched non-selective and various selective solid media, in 6 mongrel dogs. 36 dental implants (9 Ticp: titanium commercially pure; 9 TPS: titanium plasma spray; 9 HA: hidroxiapatite; 9 surfaces acid-etched) were placed in a similar distribution in all dogs 3 months after extraction of all premolars in mandible. Following a healing period of 3 months, healing abutments were installed and 45 days after cotton ligatures were placed and oral-cleaning procedures abolished for 2 months to induce vertical bone loss of about 40%. Microbial samples were with paper points on day of ligature placement and after 20, 40 and 60 days. The total number of cultivable bacteria and proportions of A. actinomycetemcomitans, Bacteroides forsythus, P. gingivalis, P. intermediate, Campylobacter sp., Capnocytophaga sp., Fusobacterium sp., Peptostreptococcus micros, Enteric Gram-negative rods, beta-hemolytic Streptococcus, Eikenella corrodens and Candida sp. were analyzed. No significant microbiological differences were observed among the different surfaces (p>0,05). Pg was not detected in the time 0; already in the times 20 and 40 were detected in 12 dental implants (4 Ticp, 4 HA, 2 TPS and 1 acid-etched surface) and in the period 60 days, in 9(2 Ticp, 3 HA, 2 TPS and 1 acid-etched surface), tends smaller affinity to eh surface with acids-etched surface. Pi was detected in 5 implants (2 Ticp, 2 HA and 1 acid-etched surface) in the period 0 and in 100% of implants in other periods. Fusobacterium sp. was detected in all the periods, tends a larger affinity to HA. Beta-hemolytic Streptococcus was detected in 6 implants (3 Ticp, 1 TPS and 2 HA) in the period 0 and 30, 26 and 24... (Complete abstract, click electronic address below). / Mestre

Resumo: Foram avaliados, clínica e radiograficamente, as reações de quatro diferentes superfícies de implante frente ao desenvolvimento e progressão da peri-implantite: Ticp: titânio comercialmente puro; TPS: titânio revestido com plasma spray de titânio; HA: hidroxiapatita; Ost. Superfícies tratadas com ácidos. Para tanto, foram utilizados seis cães, cujos pré-molares inferiores e superiores foram extraídos. Decorridos 90 dias, os implantes foram aleatoriamente colocados, e iniciou-se o controle químico e mecânico do biofilme bacteriano; após o período de osseointegração (90 dias) foram colocados os conectores, e após 45 dias da colocação dos conectores, iniciou-se a indução da peri-implantite por meio de ligaduras de fio de algodão (suspensão do controle do biofilme bacteriano), e os primeiros exames clínicos (profundidade de sondagem, sangramento à sondagem, índices de placa e sangramento, e mobilidade) e radiográficos (perda óssea) foram realizados. Esses parâmetros foram novamente avaliados após 20, 40 e 60 dias, quando da troca das lidaguras. A análise dos resultados não demonstrou diferença significante entre as superfícies, em nenhum dos parâmetros analisados, com exceção da mobilidade (avaliada pelo PeriotestÒ) e perda óssea, que foram menores nos implantes TPS. Concluiu-se que as superfícies apresentam comportamento semelhante durante a indução da peri-implantite, com exceção no parâmetros mobilidade e perda óssea, que apresentaram os implantes TPS com comportamento superior. / Abstract: The reactions of four different implant surfaces were evaluated in regard to the development and progression of peri-implantitis: titanium commercially pure (Ticp), titanium plasma spray (TPS) hidroxiapatite coated (HA) and acid attached surfaces (Ost). Six dogs had their premolars extracted. After 90 days, the implants were ramdonly placed and the dogs receive soft diet, chemical and mechanical plaque control; after the osseointegration period (90 days), the healing abutments were placed. After the healing period (45 days), the plaque control was suspended, and cotton ligatures were installed when the first clinical (probing depth, bleeding on probing, plaque index, bleeding index, and mobility) and radiographic (bone loss) exams were taken. These parameters were re-exanimate after 20, 40 and 60 days, when the ligatures were changed. The results did not show significant differences between the surfaces in any parameter observed except for the mobility (evaluated with PeriotestÒ), and bone loss. These two parameters had the TPS surface with the lower rates. It was conclude that the surfaces show similar behavior during the induction of peri-implantitis, except for the mobility and bone loss parameters witch the TPS implants had better behavior. / Orientador: Ricardo Samih Georges Abi Rached / Coorientador: Elcio Marcantonio Junior / Banca: Rosemary Adriana Chiérice Marcantonio / Banca: Luiz Antonio Pugliesi Alves de Lima / Mestre

Submitted by Rosangela Silva (rosangela.silva3@unioeste.br) on 2018-05-28T15:05:21Z No. of bitstreams: 2 Luís Henrique Cerqueira Vila Verde.pdf: 1205701 bytes, checksum: 917c89ccf0c450e4e8d17634346f026b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2018-05-28T15:05:21Z (GMT). No. of bitstreams: 2 Luís Henrique Cerqueira Vila Verde.pdf: 1205701 bytes, checksum: 917c89ccf0c450e4e8d17634346f026b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-03-03 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Vitamin D (VD) plays an important role in the development and maintenance of bone tissue. At normal levels, it has positive effect on volume, bone quality as well as its density. Considering the large number of people who present serum changes of the same, this research aims to observe the rate of hypovitaminosis D (hD) in the study population and the factors that may influence the incidence of hD, and to evaluate the influence of hD on peri-implant clinical and radiographic conditions. All the participants of the groups were submitted to a Semi-quantitative Food Frequency Questionnaire on the intake of dietary calcium (QFASQ), in order to evaluate the risk factors. Patients were submitted to laboratory tests of 25-hydroxyvitamin D dosing, those with a serum LDL level of less than 30ng / mL were allocated to the abnormal (insufficient or defficient) group and the participants with dosages equal to or greater than 30ng/mL were allocated to the normal (sufficient) group. Participants received the following evaluations: peri-implant clinical analysis (depth of probing, keratinized mucosa width, modified groove bleed index, modified plaque index), radiographic analysis (distance between the implant cervical and the mesial and distal). Patients who were allocated to the abnormal group were submitted to VD replacement, and a new clinical and radiographic analysis was performed. It was found that in the initial study population about 36% of individuals had hD. As for the food questionnaire, lower intake of milk products, such as yogurt and lower frequency of physical activities, showed a higher risk for one hD. Clinical analysis showed that VD was statistically non-statistically significant for probing depth, keratinized mucosal width, modified plaque index, and for modified bleeding index between the 2 periods, in relation to peri-implant parameters. It was concluded that less than half of the sample had hD and calcium-rich foods may contribute to normal serum levels of VD. VD did not influence the peri-implant clinical parameters studied. / A vitamina D (VD) tem um papel importante no desenvolvimento e na manutenção do tecido ósseo. Em níveis normais, ela tem efeito positivo sobre volume, qualidade óssea, bem como sua densidade. Considerando o grande número de pessoas que apresentam alterações séricas da mesma, esta pesquisa visa observar a taxa de hipovitaminose D (hD) na população estudada e os fatores que podem influenciar na incidência de hD, e avaliar a influência da hD nas condições clínica e radiográfica peri-implantar. Todos os participantes dos grupos foram submetidos a um Questionário de Frequência Alimentar Semi-quantitativo sobre a ingestão de cálcio alimentar (QFASQ), visando avaliar os fatores de risco. Os pacientes foram submetidos a exames laboratoriais de dosagem de 25- hidroxivitamina D, aqueles que apresentaram uma dosagem sérica de VD inferior a 30ng/mL foram alocados no grupo anormal (insuficiente ou deficiente) e os participantes com dosagem igual ou acima de 30ng/mL foram alocados ao grupo normal (suficiente). Os participantes receberam as seguintes avaliações: análise clínica peri-implantar (profundidade de sondagem, largura da mucosa queratinizada, índice de sangramento do sulco modificado, índice de placa modificado), análise radiográfica (distância entre a cervical do implante e as cristas ósseas mesial e distal). Os pacientes que foram alocados no grupo anormal foram submetidos à reposição da VD, e após a reposição, uma nova analise clinica e radiográfica foi realizada. Constatou-se que na população inicial do estudo cerca 36% dos indivíduos tinham hD. Quanto ao questionário alimentar, menor quantidade de ingestão de derivados do leite, como o iogurte e a menor frequência de atividades físicas mostraram maior risco para uma hD. A análise clinica demonstrou que VD se comportou, em relação aos parâmetros peri-implantares, de forma não significativa, estatisticamente, para profundidade de sondagem, largura de mucosa queratinizada, índice de placa modificado e para índice de sangramento modificado entre os 2 períodos. Concluiu-se que menos da metade da amostra apresentou hD e os alimentos ricos em cálcio podem contribuir para níveis séricos de VD normais. A VD não influenciou nos parâmetros clínicos peri-implantares estudados.

Este trabalho avaliou o comportamento eletroquímico de três ligas de níquel-cromo e duas de cobalto-cromo in vitro e in vivo. Nos estudos in vitro foram fabricados eletrodos de trabalho a partir destas ligas. Estes eletrodos ficaram imersos em meio de NaCl 0,15 mol.L-1 a 36,5°C e foram submetidos às técnicas do potencial de circuito aberto, polarização potenciostática anódica e cronoamperometria. Para os estudos in vivo foram selecionados quinze pacientes com implantes já osseointegrados e aguardando a instalação das próteses. Esses pacientes foram distribuídos aleatoriamente em cinco grupos, correspondentes às cinco ligas diferentes. Deste modo, as estruturas protéticas dos implantes foram fundidas utilizando as cinco ligas. Foi utilizada a microscopia eletrônica de varredura (MEV) e a espectroscopia por dispersão de energia (EDS) como métodos de análise das superfícies linguais metálicas das próteses, antes da instalação em ambiente oral e após seis meses de permanência. Vistas por MEV, as ligas duas de cobalto-cromo Starloy C e Remanium 2001 e duas de níquel-cromo Wiron 99 e Remanium CSe apresentaram superfícies heterogêneas caracterizadas por uma fase semelhante à matriz da liga e a outra fase, composta por elementos de maior densidade atômica, correspondente à fase interdendrítica. Após seis meses, não houve sinais de corrosão e alterações significativas na composição destas ligas. As ligas de Co-Cr avaliadas, sob o ponto de vista eletroquímico, indicam comportamento catódico quando unidas ao implante sendo um fator indicativo de proteção à corrosão. Dentro dos limites dos estudos in vitro, as ligas de Ni-Cr apresentaram um filme passivo com ampla faixa de potencial em que se mantêm passiva e ausência de corrosão localizada. A liga de níquel-cromo Dan Ceramalloy apresentou a superfície heterogênea com quatro áreas distintas (área 1 rica em titânio; área 2 rica em níquel; área 3 correspondente à matriz; área 4 rica em molibdênio). Após seis meses, as três próteses metalo-cerâmicas apresentaram as regiões correspondentes à fase 2, rica em níquel, com depressões em baixo relevo, sugerindo a oxidação com a liberação de íons níquel. Nos estudos in vitro a liga Dan Ceramalloy apresenta potencial de corrosão mais negativo, uma faixa passiva de potencial mais estreita e um filme menos protetor, quando comparada com as demais ligas estudadas. Apesar de não ter sido observado clinicamente o processo de corrosão das ligas, os estudos in vitro e in vivo deste material, permitiram verificar o seu comportamento eletroquímico e sugerir a descontinuidade do seu emprego em estruturas protéticas de implantes orais. Os estudos in vitro e in vivo apresentaram concordância para todos os materiais estudados. / In this study, the electro-chemical behavior of three nickel-chrome and two cobalt chrome alloys was studied in vitro and in vivo. In the in vitro studies, working electrodes made of these alloys were fabricated. These electrodes were immersed in a medium of NaCl 0.15 mol.L-1 at 36.5°C and were submitted to the open circuit potential, anodic potentiostatic polarization and chronoamperometry techniques. For the in vivo studies, 15 patients whose implants had osseointegrated, and who were waiting for dental implant placement, were selected. These patients were randomly distributed into five groups, corresponding to the five different alloys. Thus the prosthetic implant superstructures were cast, using the five alloys. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were used as methods to analyze the metal lingual surfaces of the prostheses, before they were placed in the oral environment, and after six months in place. Visualized by SEM, the two cobalt-chrome alloys Starloy C and Remanium 2001, and two types of nickel-chrome - Wiron 99 and Remanium Cse - presented heterogeneous surfaces characterized by a phase similar to that of the alloy matrix, and the other phase composed of elements of greater atomic density, corresponding to the interdendritic phase. After six months, there were no signs of corrosion and significant alterations in the composition of these alloys. The Co-Cr alloys evaluated, from an electrochemical point of view, indicated a cathodic behavior when united to the implant, this being a factor indicative of protection against corrosion. Within the limits of the in vitro studies, the Ni-Cr alloys presented a passive film with an ample range of potential in which they remained passive, with absence of corrosion due to pitting. The nickel-chrome alloy Dan Ceramalloy presented a heterogeneous surface with four distinct areas (Area 1 rich in titanium; Area 2 rich in nickel; Area 3 corresponding to the matrix; Area 4 rich in molybdenum). After six months, the three metal-ceramic dental prostheses presented the regions corresponding to Phase 2, rich in nickel, with depressions in low relief, suggesting oxidation with nickel ion release. In the in vitro studies, the alloy Dan Ceramalloy presented a more negative corrosion potential, a narrower range of passive potential and a less protective film, when compared with the other alloys studied. In despite of the process of corrosion of the alloys not having been clinically observed, the in vitro and in vivo studies of this material allowed verification of its electrochemical behavior, and suggest that its use in prosthetic superstructures for oral implants should be discontinued. The in vitro and in vivo studies were shown to be in agreement for all the materials studied.

L'accès aux soins dentaires est devenu, au cours de ces dernières années, un service de plus en plus demandé par la population. En particulier, la pose d'un implant, destiné à remplacer une dent manquante, en recréant une racine artificielle, devient un acte de plus en plus courant. Une des principales sources de complications entrainant l'échec de la pose d'un implant est une maladie inflammatoire : la péri-implantite. Cette maladie induit la perte des os de soutien dans les tissus entourant l'implant fonctionnel. Actuellement, il n'existe pas d'implant prévenant ces infections bactériennes, seuls des traitements curatifs sont proposés. Le développement d'un traitement antibactérien implantaire apparaît alors comme une solution préventive pertinente pour limiter les complications post-opératoires et représente un défi de santé publique. Pour parvenir à cet objectif, dans ce travail de thèse, plusieurs solutions pour préparer un revêtement implantaire bioactif ont été étudiées et évaluées. Elles sont toutes basées sur le recouvrement d'une surface modèle de titane par un polymère naturel bioactif, le chitosane. Le greffage du biopolymère au substrat a été réalisé via une liaison covalente en utilisant un agent de couplage. Les différentes étapes de la synthèse du revêtement ainsi que ses propriétés biologiques ont été caractérisées à l'aide de techniques d'analyses de chimie de surface, par des études de tenue et de restitution du biopolymère en milieu acide ainsi que par des études in vitro de l'activité antibactérienne et des propriétés biologiques des revêtements. Les résultats de ce travail ont permis de sélectionner le revêtement bioactif possédant les meilleurs propriétés pour l'application visée, notamment en raison de sa tenue en milieu acide et de son activité antibactérienne en présence des bactéries communes / In the past years, population requirement for dental care service increased. More precisely, replacement of missing tooth using dental implant is now a common intervention. As implant provides an artificial root, this procedure is permanent. The failure of the placement procedure is mainly due to an inflammatory disease: peri-implantitis. This disease leads to the death of bone tissues surrounding the dental implant. Today only curative solutions are available, and no implants can prevent bacterial development. It appears that preventing post-surgical complications by designing antibacterial implants is now a public health issue. To achieve this goal, we evaluate in this thesis different solutions to design bioactive implant coatings. We focused our work on coating of a model titanium surface by a bioactive polymer: chitosan. Polymer binding on the substrate is achieved by covalent link using a coupling agent. We described each step of the coating synthesis and characterized its biological properties using both surface chemistry analysis and cell biology techniques. We studied its behavior in an acid environment and analyzed its biological and antibacterial properties in vitro. Results of this work were used to select the bioactive coating with the best properties for the intended application, particularly due to its resistance in acidic condition and its antibacterial activity against common bacteria

Syfte: Syftet med studien är att utföra en metodutveckling där individuella skenor framställs för att möjliggöra en standardiserad mätning av plackansamling på titanfixturers ytor samtidigt som det ska ge möjlighet för att bibehålla god munhygien.   Material och metod: Sjuttio titanfixturer ytbehandlades på tre sätt: sandblästring, etsning och implantoplastik. Studien involverade elva deltagare och det framställdes elva gipsmodeller utifrån avtryck. Tolv individuella skenor utformades med modelleringsvax med hänsyn till varje deltagares bettförhållanden. Kallpolymeriserad ortokryl användes vid framställning av skenor och cylindrar. Totalt framställdes sjuttio cylindrar, där två öppningar skapades. För vardera individuella skena innefattades sex fixturer, en från varje behandlingsmetod. Fixturerna placerades enligt en randomisera mall som innefattade sex olika variationer. Den tolfte skenan utgick inte ifrån mallen utan där placerades fyra fixturer, två av implantoplastik, en etsad och en blästrad. Skenorna lämnades ut till de frivilliga deltagarna och användes under tre dygn.   Resultat: Metodutvecklingen för att mäta plackansamling på olika ytbehandlade fixturer med hjälp av individuella skenor i förhållande till god munhygien, gick att genomföra. Resultaten visade att den råa ytan efter sandblästring hade högst plackansamling (0,604 mm), medan implantoplastik hade lägst plackansamling (0,342 mm).  Slutsats: Inom ramen för föreliggande studie kan följande slutsats dras: Genom framställning av individuella skenor är det möjligt att mäta plackansamlingen på etsade, blästrade och implantoplastik-ytbehandlade titanfixturer. Resultaten uppvisar även en tydlig indikation på att passform och komfort är en viktig faktor för deltagarnas medverkan. / Purpose: The purpose of this study is to perform a method development where individual splints are produce to enable a standardized measurements of plaque accumulation on the surfaces of titanium fixtures, while allowing to maintain good oral hygiene.    Material and method: Seventy titanium fixtures were surface-treated in three ways; sandblasting, etching, and implantoplasty. The study involved eleven participants, and eleven gypsum models were created. Twelve individual splints were designed using modeling wax, taking into consideration each participant's occlusal conditions. Cold-polymerized orthocryl was used to fabricate the splints and cylinder. A total of seventy cylinders were prepared, each with two openings. Each individual splint included six fixtures, one from each treatment method. The fixture placement followed a randomized pattern, comprising six different variations. The twelfth splint deviated from the randomized pattern and contained four fixtures: two from implantoplasty, one etched, and one sandblasted.    Results: The method development for measuring plaque accumulation on different surface-treated fixtures using individual splints in relation to good oral hygiene, was successfully conducted. The results demonstrated that the rough surface following sandblasting exhibited the highest plaque accumulation (0,604 mm), whereas implantoplasty showed the lowest plaque accumulation (0,342 mm).    Conclusion: Within the scope of this study, the following conclusion can be drawn: By individual splints, it is possible to measure plaque accumulation on etched, sandblasted, and implantoplasty-treated titanium fixtures. The results show a clear indication that fit, and comfort are important factors for participant’s compliance.

No description available.

Les péri-implantites se caractérisent par une destruction inflammatoire irréversible des tissus qui entourent l’implant dentaire. Leur pathogénie est proche des parodontites, maladies inflammatoires chroniques d’étiologie bactérienne entrainant une destruction irréversible de l’os alvéolaire soutenant les dents. Cependant, la réponse inflammatoire et la résorption osseuse diffèrent entre péri-implantites et parodontites. De plus, les traitements conventionnels non chirurgicaux ne sont pas efficaces pour le traitement des péri-implantites. L’objectif de notre travail est d’analyser les différences entre les médiateurs inflammatoires et cataboliques des tissus péri-implantaires en comparaison aux tissus parodontaux malades après une thérapie conventionnelle non chirurgicale. Nous avons bâti une collection biologique d’explants humains de tissus conjonctifs péri-implantaires ou parodontaux malades. Une analyse Multiplex des milieux conditionnés et histologiques des explants a révélé une expression accrue de l’inhibiteur de métalloprotéase TIMP-2, de l’interleukine IL-10 et du RANK-L dans les tissus péri-implantaires. En accord avec une revue de littérature que nous avons mené dans la seconde partie de notre travail, notre hypothèse est que ces différences s’expliqueraient, tout du moins en partie, par la présence de particules de titane au niveau des tissus péri-implantaires. Notre travail participe à la compréhension de la pathogenèse de la maladie et concourt à l’identification de biomarqueurs potentiels pour le pronostic ou le développement d’approches thérapeutiques. / Peri-implantitis lesions present an irreversible destruction of the peri-implant surrounding tissues. The pathogenic pathway of peri-implantitis is close from the one of periodontitis which is a chronic inflammatory disease caused by a bacterial biofilm leading to irreversible supportive bone destruction around teeth. Still, the inflammatory process and the bone destruction differ between the two diseases. In addition, conventional non-surgical treatments are not effective for the treatment of peri-implantitis. The aim of our work is to analyze the differences between inflammatory and catabolic mediators of peri-implant tissues compared to diseased periodontal tissues after conventional non-surgical therapy. We have constructed a biological collection of human explants of peri-implant or periodontal connective tissue. Multiplex assays of the conditioned media and histological analysis of the explants revealed an increased expression of the TIMP-2 metalloprotease inhibitor, interleukin IL-10, and RANK-L in the peri-implant tissues. In agreement with a review of literature that we conducted in our work, our hypothesis is that these differences can be explained, at least partly, by the presence of titanium wear particles in the peri-implant tissues. Our work contributes to the understanding of the pathogenesis of the disease and contributes to the identification of biomarkers.

Orientador: Paulo Sérgio Flores Campos / Texto do capítulo 1 em inglês / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba / Made available in DSpace on 2018-08-20T12:07:20Z (GMT). No. of bitstreams: 1 Vaz_SergioLinsdeAzevedo_M.pdf: 1201820 bytes, checksum: c01a9a7bcc2ca60b934986c91f46e192 (MD5) Previous issue date: 2012 / Resumo: O objetivo neste trabalho foi identificar a exatidão de alguns filtros de imagem na mensuração do nível ósseo peri-implantar, por meio da radiografia digital. Para isso, vinte implantes de titânio (Titamax, Neodent, Curitiba, PR, Brasil) foram instalados em seis fragmentos de costelas bovinas, nas quais foram criados defeitos do tipo perda óssea. Utilizando um sistema intra-bucal de placas de fósforo (Vista Scan, Dürr Dental, Beitigheim-Bissingen, Alemanha), radiografias periapicais foram realizadas posicionando os implantes segundo a técnica do paralelismo. Após a obtenção das imagens, nove filtros do software DBSWIN foram aplicados: fine, caries 1, caries 2, perio, endo, noise reduction, invert, emboss e sculpture. Um avaliador mensurou as distâncias entre o ombro do implante à porção mais apical do defeito no software Image J. Os defeitos também foram mensurados nas costelas bovinas utilizando um paquímetro digital. O teste não-paramétrico de Friedman comparou os valores obtidos nas imagens com aplicação dos filtros aos encontrados nas imagens originais e nas costelas bovinas, adotando nível de significância de 5%. Os resultados mostraram diferenças estatisticamente significantes para os filtros caries1, caries2, endo e perio (P < 0.05) tanto em relação às imagens originais, quanto em relação às mensurações obtidas com o paquímetro. As mensurações obtidas com as imagens originais, filtros fine e emboss foram mais próximas às obtidas com o paquímetro. Concluiu-se que os filtros fine e emboss foram os mais exatos na mensuração do nível ósseo peri-implantar, sendo equiparáveis às imagens originais. Os filtros caries1, caries2, endo e perio foram os menos exatos, não sendo indicados para este fim / Abstract: This study aimed to identify the accuracy of some enhancement filters of an intraoral phosphor-plate system for measuring the simulated periimplant bone level. Twenty titanium implants (Titamax, Neodent, Curitiba, PR, Brazil) were placed into six fragments of bovine ribs and defects simulating bone loss were created. Periapical radiographs were taken with a phosphor-plate system (Vista Scan, Dürr Dental, Beitigheim-Bissingen, Germany) according to the paralleling standard technique, and nine enhancement filters were applied: fine, caries 1, caries 2, perio, endo, noise reduction, invert, emboss and sculpture. An oral radiologist measured on the Image J software the distance from the neck of the implant to the most apical contact of the bone with the implant. The Friedman non-parametric test compared the radiographic measurements to those obtained on the bovine ribs with a digital caliper. The significance level adopted was 5%. The caries1, caries2, endo, and perio filters resulted on measurements statistically different from both the original images and the measures of the digital caliper (P < 0.05). In conclusion, the fine and emboss filters resulted on the most precise filters, with similar measures to the original images. The caries1, caries2, endo, and perio filters were the less accurate for measuring the periimplant bone level / Mestrado / Radiologia Odontologica / Mestre em Radiologia Odontológica

No description available.