Conselho Nacional de Desenvolvimento Científico e Tecnológico / Protection of irrigated rice plants using fungicides is growing every year as observation of fungal diseases is increasing. Higher occurrence of disease is observed when seeding is conducted after the recommended period. Success of rice yield depends on several steps since the implantation of the culture until harvest, being the last a very important step especially for physical and physiological rice quality. Rice production cycle will be only completed with grains and seeds storage, which consists in preserving physiological seed quality for new crops or grain quality for consumption and industrialization. The research was conducted using three field experiments in crop season 2008/09, with the intention of characterizing the response of different rice genotypes to fungicides application with a formulated mixture of propiconazole + trifloxystrobin applied at different developmental stages in a late seeding crop (Chapter I), quality of grain and seeds with different harvest moisture according to the fungicide application moment for different cultivars (Chapter II) and the behavior of grain and seeds to storage in controlled condition of temperature and humidity and in normal conditions (Chapter III). Experiments were conducted in a lowland area of the Crop Department of the Federal University of Santa Maria (UFSM). Each experiment was constituted by a suitable factorial scheme. Use of fungicide in different irrigated rice genotypes late sown showed to be efficient to high productivity. Harvest conducted with rice grain moisture under the recommended by researches demonstrated reduction of physical and physiological rice quality. There was less reduction in quality when two fungicide applications were performed. Increasing seed storage time caused reduction in physiological seed quality independently of storage in controlled condition or in normal conditions. Use of fungicide reduced the intensity of seed deterioration and incidence of fungus associated to seeds. Percentage of whole grain increased with storage time. / A tecnologia de proteção de plantas de arroz irrigado através da utilização de fungicidas se amplia a cada ano, na medida que se observa elevação da ocorrência de doenças fúngicas, fato este mais evidente em semeaduras realizadas após a época preferencial recomendada. O sucesso da lavoura de arroz depende de várias etapas, que compreendem desde a implantação da cultura até a colheita, sendo esta uma etapa importante para a qualidade física e fisiológica do arroz. O ciclo da produção de arroz finaliza com o armazenamento de grãos e sementes, o qual consiste na preservação da qualidade fisiológica das sementes para novos cultivos ou da qualidade dos grãos para consumo e industrialização. As ações de pesquisa foram conduzidas no campo, com três experimentos, durante a safra de cultivo de 2008/09, com o objetivo de caracterizar a resposta de genótipos de arroz irrigado à aplicação de fungicida com mistura formulada de propiconazol + trifloxistrobina na parte aérea das plantas, em diferentes estádios de desenvolvimento da cultura, em semeadura tardia (Capítulo I). Também se procurou avaliar a qualidade de grãos e sementes colhidos com diferentes graus de umidade, em função do momento da aplicação de fungicida em diferentes cultivares (Capítulo II), e o comportamento quanto ao armazenamento em condições controladas de temperatura e da umidade relativa do ar com as condições normais (Capítulo III). Os experimentos foram conduzidos no campo, na área de várzea do Departamento de Fitotecnia da Universidade Federal de Santa Maria (UFSM), utilizando delineamento experimental de blocos ao acaso, com quatro repetições. Cada experimento foi constituído pelo delineamento fatorial adequado aos fatores em análise. O uso de fungicida em arroz irrigado semeado em época tardia mostra-se eficiente para obtenção de elevada produtividade de grãos. Colheitas realizadas com grau de umidade médio do arroz abaixo do preconizado pela pesquisa apresentam redução na qualidade física e fisiológica do arroz; ocorrem menores perdas quando são realizadas duas aplicações de fungicida. O armazenamento das sementes aponta para uma redução de sua qualidade fisiológica com o decorrer do tempo, independentemente do local, com monitoramento de temperatura e umidade relativa do ar ou em condições normais. O uso de fungicida reduz a intensidade da deterioração e a incidência de fungos associados a sementes. O percentual de grãos inteiros aumenta com o tempo de armazenamento.

Made available in DSpace on 2014-06-11T19:25:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-11-05Bitstream added on 2014-06-13T19:32:36Z : No. of bitstreams: 1 crocco_flt_me_mar.pdf: 540020 bytes, checksum: 0bd5a165526be92c67036637564b7db5 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Este trabalho pretende analisar aspectos específicos da transformação da ideologia, elaborada inicialmente por Karl Marx em relação à abordagem promovida posteriormente no século XX pela Teoria Crítica. O trabalho está dividido em dois momentos, inicialmente analisamos a fundamentação e elaboração do conceito de ideologia na teoria marxiana. Procuramos analisar conjuntamente os principais pensamentos que influenciaram a teoria de Marx a fim de mergulharmos em suas reflexões sobre a ideologia. A ideologia é central em toda sua obra e possui várias implicações conceituais. Durante sua vida e produção, Marx abordou este conceito de formas distintas, provocando, em seu percurso teórico, diferentes leituras. A primeira parte será destinada ao estudo da concepção marxista tradicional sobre o conceito de ideologia e, posteriormente, sua elaboração na teoria da reificação de Lukács, em que são aprofundados certos questionamentos da teoria marxiana e possibilitadas novas abordagens da realidade social. O segundo momento deste trabalho consiste na elaboração e análise do conceito de ideologia para a Teoria Crítica, representada aqui por Horkheimer Adorno e Marcuse. A constituição e o desenvolvimento do conceito na Teoria Crítica caracterizam-se por um aspecto de extrema complexidade e heterogeneidade. Inseridos no Instituto de Pesquisa Social, o estudo destes teóricos podem ser abordados singularmente, mesmo que muitos trabalhos realizados tenham nascido de parcerias e de preocupações a partir de uma mesma problemática. A ideologia era enfocada num primeiro momento, em seu aspecto marxista tradicional como esfera da dissimulação da dominação, graças ao encobrimento da materialidade. Diferentemente, no segundo momento do trabalho, analisado aqui através dos teóricos frankfurtianos, a ideologia passou a ser abordada de acordo com parâmetros qualitativamente... / The present study intends to investigate specific aspects of the ideology concept transformation elaborated initially by Karl Marx in relation to the approach promoted later in 20th century by Critical Theory. This study is divided into two moments and initially we analyzed the principles and elaboration of the ideology concept within Marxist theory. We investigated the main thoughts that influenced Marx’s theory in order to go deeper in his specific analyses on the ideology concept. The theory of the ideology is central in all his work and holds several conceptual implications. During his life and production, Marx approached this concept in different ways, provoking, in his theoretical course, different readings. The first part will be destined to the study of the traditional Marxist conception on the ideology concept and, later, its elaboration in the theory of reification of Lukács. Certain discussions of Marxinian theory will be deepened and new approaches of social reality will be possible. The second moment of this study consists of the elaboration and analysis of the ideology concept for the Critical Theory, here represented by Horkheimer, Adorno and Marcuse. The constitution and the development of the concept in Critical Theory are characterized by an aspect of extreme complexity and heterogeneity. Placed at the Institute of Social Research, the study of these theoretical researchers can be approached singularly, even if many accomplished works have been born from partnerships and from apprehensions starting from a same problem. The ideology was focused in a first moment, in its traditional Marxist aspect as sphere of the dominance dissimulation, credited to the covering of the materiality. Differently, in the second moment of this study, investigated here through the Frankfurtians, the ideology started to be approached according to different qualitative... (Complete abstract click electronic access below)

abstract: Despite nearly five decades of archaeological research in the Romanian Carpathian basin and adjacent areas, how human foragers organized their stone artifact technologies under varying environmental conditions remains poorly understood. Some broad generalizations have been made; most work in the region is concerned primarily with descriptive and definitional issues rather than efforts to explain past human behavior or human-environmental interactions. Modern research directed towards understanding human adaptation to different environments remains in its infancy. Grounded in the powerful conceptual framework of evolutionary ecology and utilizing recent methodological advances, this work has shown that shifts in land-use strategies changes the opportunities for social and biological interaction among Late Pleistocene hominins in western Eurasia, bringing with it a plethora of important consequences for cultural and biological evolution. I employ, in my Dissertation, theoretical and methodological advances derived from human behavioral ecology (HBE) and lithic technology organization to show how variability in lithic technology can explain differences in technoeconomic choices and land-use strategies of Late Pleistocene foragers in Romanian Carpathians Basin and adjacent areas. Set against the backdrop of paleoenvironmental change, the principal questions I addressed are whether or not technological variation at the beginning of the Upper Paleolithic can account for fundamental changes at its end. The analysis of the Middle and Upper Paleolithic strata, from six archaeological sites, shows that the lithic industries were different not because of biocultural differences in technological organization, landuse strategies, and organizational flexibility. Instead the evidence suggests that technoeconomic strategies, the intensity of artifact curation and how foragers used the land appear to have been more closely related to changing environmental conditions, task-specific activities, and duration of occupation. This agrees well with the results of studies conducted in other areas and with those predicted from theoretically-derived models based on evolutionary ecology. My results lead to the conclusion that human landuse effectively changes the environment of selection for hominins and their lithic technologies, an important component of the interface between humans and the natural world. Foragers move across the landscape in comparable ways in very different ecological settings, cross-cutting both biological morphotypes and prehistorian-defined analytical units. / Dissertation/Thesis / Doctoral Dissertation Anthropology 2015

Despite a high degree of individualism, associationism is extensive in Sweden, and it is said to have contributed to the democratization of Swedish society. Cultural associations constitute a significant part of the cultural range. In recent years, however, alarming reports of reduced involvement and membership numbers have been announced. The purpose of this study is to qualitatively investigate how cultural associations in Karlstad's municipality relate to general social development with a reduced membership flow in the associationism. The survey was conducted through semi-structured interviews with persons who have a trust assignment or some other relationship with cultural associations in Karlstad. The result was analyzed by content analysis. The survey shows a consistent view that there is a problem about either the commitment or the number of members and that the situation has changed over time, but also that the complexity of differences between different cultural associations makes it impossible to draw a general conclusion about the cultural associations as a unit. Generally, people with trust assignments in cultural associations experience the cultural associations standing stable. Some associations decrease in size or disappear, while others start or expand their activities. Persons with trust assignments within and in relation to cultural associations, holds a consistent view of the importance of associations for the rest of society, as they are considered important for democracy.

Submitted by Vanessa De Moraes (vanmoraes77@hotmail.com) on 2018-07-14T20:16:07Z No. of bitstreams: 1 Análise de fatores que levaram ao encaminhamento tardio em casos novos de câncer de próstata recebidos no Hospital Amaral Carvalho nos anos de 2015 e 2016.pdf: 2014135 bytes, checksum: a5eb85dede60a04ea178395c9a8b13cf (MD5) / Approved for entry into archive by Luciana Pizzani null (luciana@btu.unesp.br) on 2018-07-16T12:51:55Z (GMT) No. of bitstreams: 1 moraes_v_me_bot.pdf: 2014135 bytes, checksum: a5eb85dede60a04ea178395c9a8b13cf (MD5) / Made available in DSpace on 2018-07-16T12:51:55Z (GMT). No. of bitstreams: 1 moraes_v_me_bot.pdf: 2014135 bytes, checksum: a5eb85dede60a04ea178395c9a8b13cf (MD5) Previous issue date: 2018-05-23 / O câncer de próstata é o tipo de tumor de maior incidência nos homens, atrás somente do câncer de pele não melanoma, é o segundo em mortalidade no Brasil, sendo um grave problema de saúde pública, pois mesmo sendo um câncer de crescimento lento e de simples detecção, muitos pacientes descobrem tardiamente a doença, diminuindo as chances de cura e de sobrevida. Os objetivos da pesquisa foram: desvelar alguns dos motivos do diagnóstico e encaminhamento tardio para um serviço de referência; analisar quais regiões encaminharam pacientes mais tardiamente e entender o itinerário terapêutico desses pacientes. Trata-se de uma pesquisa quanti-qualitativa, desenvolvida em duas etapas. No 1º momento realizou-se um estudo retrospectivo, descritivo e quantitativo de dados levantados junto ao RHC, de 1531 pacientes com câncer de próstata recebidos no Hospital Amaral Carvalho em 2015 e 2016. Na segunda etapa foi realizado um estudo qualitativo, com realização de 100 entrevistas, com perguntas fechadas e abertas. Entre os resultados destaca-se que a maioria dos pacientes está acima de 50 anos (97,77%), com média de 66 anos. A faixa etária de 70 a 79 anos apresentou o maior número de óbitos (3,66%) do total de 141 (9,21%), sendo o maior índice de pacientes com estádio IV (4,25%). 28,15% (431) dos pacientes chegaram com estádio avançado, sendo 131 da DRS VI (Bauru), 85 da DRS IX (Marília), 84 da DRS XVI (Sorocaba), 52 da DRS III (Araraquara) e os demais casos em menores números das demais DRS. Na 2ª etapa da pesquisa, constatou-se que dos 100 pacientes entrevistados: 78 são casados, 41 possuem de 3 a 4 filhos, 50 estudaram até o 4º ano, 67 já estão aposentados, 79 buscaram atendimento SUS. Dos sujeitos, 76 se autonomearam brancos, 68 não fumantes, 56 pacientes afirmaram possuir familiares com câncer, sendo o familiar mais citado foi o pai (21), e o câncer de próstata o de maior prevalência. Ainda 70 pacientes declararam fazer exames de prevenção, 55 tiveram sintomas, apenas 20 relataram encontrar dificuldades no encaminhamento ao serviço especializado e 43 aguardaram menos de um mês para o atendimento no HAC. A pesquisa constatou que os casos de pacientes com estágios mais avançados (III e IV) somaram 24,85% em 2015 e 32,53% em 2016. Os valores culturais relacionados à masculinidade se destacaram como o principal motivo do encaminhamento tardio destes pacientes. A desorganização e a falta de comprometimento de alguns profissionais da saúde básica também foram obstáculos no acesso aos serviços de alta complexidade. Como proposta de auxílio na detecção precoce do câncer de próstata, sugerimos: definição de um consenso sobre rastreamento; capacitação dos profissionais da rede básica para atendimento desta clientela; priorização de campanhas e trabalho coletivo com equipe multiprofissional; horário diferenciado para atendimento / Prostate cancer is the second most common type of tumor in men, behind only non-melanoma skin cancer. It is the second most common type of cancer in Brazil, being a serious public health problem. simple detection, many patients belatedly discover the disease, decreasing the chances of cure and survival. The objectives of the research were: to unveil some of the reasons for the diagnosis and late referral for a referral service; to analyze which regions referred patients later and to understand the therapeutic itinerary of these patients. It is a quantitative qualitative research, developed in two stages. A retrospective, descriptive and quantitative study of 1531 prostate cancer patients received at the Amaral Carvalho Hospital in 2015 and 2016 was carried out in the 1st stage. A second qualitative study was carried out with 100 interviews, with closed and open questions. Among the results it is highlighted that the majority of patients are over 50 years (97.77%), with a mean of 66 years. The age group from 70 to 79 years old had the highest number of deaths (3.66%) out of 141 (9.21%), being the highest rate of patients with stage IV (4.25%). 28,15% (431) of the patients arrived at an advanced stage, 131 of the DRS VI (Bauru), 85 of the DRS IX (Marília), 84 of the DRS XVI (Sorocaba), 52 of the DRS III (Araraquara) and the other cases in smaller numbers of the other DRS. In the second stage of the research, it was verified that of the 100 patients interviewed: 78 are married, 41 have 3 to 4 children, 50 have studied until the 4th year, 67 are already retired, 79 have sought SUS care. Of the subjects, 76 became white, 68 were non-smokers, and 56 patients reported having relatives with cancer. The most frequent family member was the father (21), and prostate cancer was the most prevalent. In addition, 70 patients reported having had preventive exams, 55 had symptoms, only 20 reported having difficulty in referral to the specialized service, and 43 waited less than one month for care at HAC. The research found that the cases of patients with more advanced stages (III and IV) totaled 24.85% in 2015 and 32.53% in 2016. The cultural values related to masculinity were the main reason for the late referral of these patients. The disorganization and lack of commitment of some basic health professionals have also been obstacles in accessing high complexity services. As a proposal to aid in the early detection of prostate cancer, we suggest: definition of consensus on screening; training of professionals in the basic network to serve this clientele; prioritization of campaigns and collective work with multiprofessional team; differentiated service hours.

Cognitive reappraisal is an emotion regulation strategy that has been shown effective in down-regulating negative emotions in both psychological and electrophysiological measures. Although there are many studies on cognitive reappraisal, only recently have there been studies differentiating between various ways of employing the strategy. This event-related potential (ERP) study sets out to compare the efficiency and temporal dynamics of three cognitive reappraisal techniques – situation-focused reappraisal, social distancing, and temporal distancing – by measuring their effects on emotional responses to aversive pictures, as indexed by the affective ERP component the late positive potential (LPP). EEG data was recorded from 17 participants. The results revealed no significant differences between emotion regulation strategies and baseline for the total ERP epoch (3,000 ms). When differentiating between early (400-800 ms), mid (800-1,500 ms), and late (1,500-3,000) periods of the epoch, significance was found in some conditions, but since no significant overall LPP activity was found, these numbers are difficult to interpret.

Wood has been an integral part of the Scandinavians everyday life for thousands of years. There are still several substantial gaps in knowledge about their wood culture during the Late Iron Age since previous research has been focused on more common findings of inorganic materials like ceramics, metals and glass. Archaeologists rarely find wooden artifacts during excavations due to wood disintegrating a lot faster than metal in the ground. Valsgärde is one of Sweden’s most important Iron Age sites since several wooden remains were found there. They show parts of our distant past that we have yet to understand and gain knowledge about. The few preserved wooden artifacts from the Late Iron Age show a rich culture of wood carving. That is why this study focuses on those very few organic objects that are found. Wooden artifacts might potentially be used to determine the social status of the individuals in the graves. This is examined through a comparative analysis of the wooden remains from Valsgärde and other boat graves in Scandinavia. The analysis also reveals what type of wood the artifacts were made of, which makes it possible to determine if they could be from local trees or if they had to be imported. There seems to be a conscious choice of what kind of wood an object should be made of depending on the purpose at hand and social status. In some cases the choice of wood also seems to be based on the symbolic or mythological meaning of the artifact. This study uses previous microscopic wood analysis from the boat graves to give a more in-depth picture of the Scandinavian Late Iron Age wood culture as a whole.

Made available in DSpace on 2014-06-11T19:23:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-02-23Bitstream added on 2014-06-13T20:51:01Z : No. of bitstreams: 1 pereira_ez_me_jabo.pdf: 262492 bytes, checksum: 9be8063c009d87911f7792e38907fec9 (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / Com o objetivo de investigar a importância de ferramentas que possam identificar as arritmias ou detectar seus possíveis fatores desencadeantes em portadores da cardiomiopatia arritmogênica do ventrículo direito, 25 cães Boxers foram submetidos ao exame eletrocardiográfico convencional (ECG) e variabilidade da frequência cardíaca (VFC), obtida pela avaliação Holter de 24 horas, e 20 foram submetidos ao exame eletrocardiográfico de alta resolução (ECGAR). Os cães foram divididos em três grupos de acordo com o número de extrassístoles ventriculares (EV) obtidas pela avaliação Holter. O GC foi composto por cães apresentando menos de 20 EV/24 horas, o GD1 foi formado por animais com mais de 100 e menos de 1.000 EV/24 horas, enquanto o GD2 foi composto por animais que apresentaram mais de 1.000 EV/24 horas. Levando em consideração a presença de EV e extrassístoles supraventriculares (ESV) no ECG, este teste apresentou 83,33% de sensibilidade, 100% de especificidade, valor preditivo positivo (VPP) de 100% e valor preditivo negativo (VPN) de 86%. Os parâmetros da VFC SDNNIDX (Gc: 194,08 ± 56,29 ms; GD1: 202,20 ± 94,79 ms; GD2: 118,00 ± 43,76 ms) e pNN>50 (Gc: 39,75 ± 12,69 ms; GD1: 46,24 ± 14,08; GD2: 21,52 ± 9,27 ms) foram significativamente menores nos pacientes do GD2. O ECGAR apresentou sensibilidade de 30%, especificidade de 50%, VPP de 37,5% e VPN de 41,67%. Assim, os resultados sugerem que a eletrocardiografia convencional e a VFC são técnicas que podem contribuir substancialmente no diagnóstico da CAVD em cães Boxers, ao contrário da eletrocardiografia de alta resolução que se mostrou ineficaz em identificar a presença de potenciais tardios nos pacientes com esse grau de doença / Aiming to investigate the importance of tools that could identify arrhythmias or detect its possible inciting factor in patients affected by arrhythmogenic right ventricular cardiomyopathy, 25 Boxer dogs were submitted to conventional electrocardiogram (ECG), heart rate variability (HRV), obtained by 24-hours Holter evaluation, and 20 were submitted to high resolution electrocardiogram (HRECG). Dogs were divided into three different groups according to the number of ventricular complexes (VC) obtained in Holter analysis. The GC was formed by dogs presenting less than 20 VC/24 hours, the GD1 was formed by animals presenting more than 100 and less than 1.000 VC/24 hours, while the GD2 was composed of dogs presenting over a 1.000 VC/24 hours. Considering the presence of ventricular or supraventricular complexes on the ECG, this test had 83,33% of sensitivity, 100% of specificity, positive predictive value (PPV) of 100% and negative predictive value (NPV) of 86%. The HRV parameters SDNNIDX (Gc: 194.08 ± 56.29 ms; GD1: 202.20 ± 94.79 ms; GD2: 118.00 ± 43.76 ms) and pNN>50 (Gc: 39.75 ± 12.69 ms; GD1: 46.24 ± 14.08; GD2: 21.52 ± 9.27 ms) were significantly lower in the patients of GD2. The HRECG showed 30% of sensitivity, 50% of specificity, PPV of 37,5% and NPV of 41,67%. Thus, the results suggest that conventional ECG and HRV are techniques that can strongly contribute in the diagnosis of ARVD in Boxer dogs, opposed to HRECG that showed itself inefficient to detect the presence of late potentials in patients with this degree of disease

Introdução: A recorrência de crises epiléticas pós cirurgia para tratamento da epilepsia do lobo temporal tem sido classificada como precoce ou tardia dependendo do tempo da primeira crise depois do procedimento. Contudo, este tempo de recorrência é variado, sendo arbitrariamente definido nos artigos científicos. Objetivos: Nós desenvolvemos um modelo matemático que pode identificar pacientes com chance de recorrência de crises pós-operatórias precoces ou tardias. Após, analisamos os dois grupos para identificar as diferenças clínicas, eletrofisiológicas e de neuroimagem entre estes pacientes. Métodos: Uma coorte histórica com 247 pacientes tratados com cirurgia para epilepsia do lobo temporal foi estudada. Dentre os paciente onde as crises epiléticas retornaram, utilizamos o tempo de recorrência em uma curva ROC para avaliar com maior acurácia o melhor período para predizer o prognóstico cirúrgico a longo prazo. Com isto, dividimos os pacientes em dois grupos: os de recorrência precoce e os de recorrência tardia. Após, nós analisamos as diferenças clínicas e radiológicas entre estes pacientes. Resultados: As crises epiléticas retornaram em 107 (48.9%) pacientes. A curva ROC mostrou que 6 meses era o tempo onde o prognóstico a longo prazo poderia ser determinado com maior acurácia (AUC = 0.761; sensibilidade = 78.8%; especificidade = 72.1%). Nós observamos que nos pacientes onde a recorrência ocorreu nos primeiros 6 meses após a cirurgia, a epilepsia começou mais precocemente (OR: 6.034; CI95%: 1.056–11.013; p=0.018), estes pacientes possuíam um pior prognóstico (6.849;2.538–18.518;p=0.001), necessitaram de maior número de medicação anti-epilética após o procedimento (2.07;1.162–9.345;p=0.013) e mais freqüentemente foram submetidos a uma nova cirurgia para controle de crises (9.592;1.181–77.877;p=0.021). Nos pacientes com recorrência tardia, as crises epiléticas eram mais comumente associadas a fatores desencadeantes (9.615;3.521–26.315;p<001). Conclusão: Pacientes com recorrências de crises epiléticas precoces ou tardias possuem diferentes características que podem estar relacionadas a diferenças entre os tipos de zonas epileptogênicas, eficácia dos procedimentos cirúrgicos ou mesmo à própria epileptogenicidade. A existência de tais disparidades podem ajudar a explicar os diferentes padrões de recorrência de crises pós cirurgia para epilepsia, auxiliando no planejamento do tratamento destes pacientes a longo prazo. / Background: Recurrence of seizures after surgery for epilepsy has been generally classified as either early or late depending on the time between surgery and seizure recurrence. However, the time of seizure recurrence is variable and it has been arbitrarily defined in the literatures. Objective: Here we establish a statistical-based model for discriminating patients with early or late seizure recurrence and examine the clinical, electrophysiological, and neuroimaging differences between these two groups of patients. Methods: A historical cohort of 247 patients treated surgically for temporal lobe epilepsy was identified. In those patients who recurred, the post-operative time until seizure recurrence was examined using an ROC curve to discriminate with greater accuracy the best period for predicting the long-term prognosis of patients. This approach divided patients in two groups, those with early and those with late seizure recurrence. Following this division, we compared differences between these groups in terms of a number of clinical and radiological variables. Results: Seizures recurred in 107 (48.9%) patients. The ROC curve showed that 6 months was the time when long-term surgical outcome could be determined with best accuracy, (AUC = 0.761; sensitivity = 78.8%; specificity = 72.1%). We observed that patients with seizure recurrence during first 6 months after surgery started seizing at younger age (OR: 6.034; CI95%: 1.056–11.013; p=0.018), had a worse outcome (6.849;2.538–18.518;p=0.001), needed a higher number of antiepileptic medications after surgery (2.07;1.162–9.345;p=0.013) and were more frequently submitted to reoperations (9.592;1.181–77.877;p=0.021). Patients with late relapse more frequently had seizures associated with trigger events (9.615;3.521–26.315;p<001). Conclusion: Patients with early or late recurrence of seizures have different characteristics that might reflect diversity in the epileptogenic zone and epileptogenicity itself. These disparities might help to explain variable patterns of seizures recurrence after epilepsy surgery.

During the Late Quaternary, abrupt climate and cultural changes took place and made alternations to the past landscape. Climatic phenomena such as expand of ice masses,sea level rise, high and low temperatures, migration of humans, decline and increase of forest areas and more changes were the reason of changing the biodiversity of species and the formation of the land. Here cartographic maps with the use of GIS will be presented from reconstructions of the environment during the Late Quaternary, which then will be interpreted from coleopteran fossils for the whole of Europe. Furthermore, living and extinct species will be compared, in which the focus of the extinction will be in the British Isles. Each period will show a different abundance of species, the regional disappearance of the species will be depicted by the abrupt changes in the landscape during the past. Anthropogenic and natural factors will be discussed and be compared with the habitats of the species.