151 |
Efeitos da atividade física sobre a memória e estresse oxidativo plasmático e hipocampal de ratas na senescência / Effects of physical activity on memory, plasma and hippocampal oxidative stress of rats on senescenceRamires, Maria Luiza Gregolin [UNESP] 25 July 2017 (has links)
Submitted by MARIA LUIZA GREGOLIN RAMIRES null (luizafoaunesp@gmail.com) on 2017-09-21T11:46:41Z
No. of bitstreams: 1
DISSERTAÇAO ULTIMA VERSAO PDF.pdf: 1223743 bytes, checksum: 45c357a33b824bc50d4e4a7bed9ea91d (MD5) / Approved for entry into archive by LUIZA DE MENEZES ROMANETTO (luizamenezes@reitoria.unesp.br) on 2017-09-21T14:03:27Z (GMT) No. of bitstreams: 1
ramires_mlg_me_araca.pdf: 1223743 bytes, checksum: 45c357a33b824bc50d4e4a7bed9ea91d (MD5) / Made available in DSpace on 2017-09-21T14:03:27Z (GMT). No. of bitstreams: 1
ramires_mlg_me_araca.pdf: 1223743 bytes, checksum: 45c357a33b824bc50d4e4a7bed9ea91d (MD5)
Previous issue date: 2017-07-25 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Há evidências que a prática regular de atividade física potencializa a memória, diminui o estresse oxidativo plasmático e hipocampal e a ansiedade na senescência. Neste trabalho foram utilizadas 40 ratas (Rattus norvegicus albinus, Wistar), com 13 meses de idade ao início do experimento, divididas em quatro grupos: um grupo controle (GC) e três grupos tratamento (GT1, GT2 e GT3), sendo 10 animais em cada grupo. O grupo controle foi mantido apenas sob observação. Aos grupos tratamento foram aplicados exercícios físicos e de memória, sendo que ao GT1, apenas exercícios de memória; ao GT2 escalada em escada, e ao GT3 ambos os exercícios. Os animais que foram submetidos à escalada em escada três vezes por semana durante três meses consecutivos e aos testes de memória, apresentaram melhor desempenho nas memórias de curto e longo prazo e de habituação, bem como menor ansiedade em teste de campo aberto. A baixa concentração de malonaldeído (MDA), o equilíbrio da superóxido dismutase (SOD) e o aumento da capacidade antioxidante total (Ferric Reducing Antioxidant Power- FRAP, foram observados nas amostras plasmáticas e hipocampais de ratas submetidas aos tratamentos. Concluiu-se que a prática de exercício físico regular associado a exercícios de memória melhorou as capacidades mnemônicas, diminuiu o estresse oxidativo e a ansiedade de ratas na senescência. / There is evidence that regular physical activity enhances memory, decreases plasma and hippocampal oxidative stress, and anxiety in senescence. In this work, 40 rats (Rattus norvegicus albinus, Wistar), 13 months old at the start of the experiment, were divided into four groups: one control group (CG) and three treatment groups (GT1, GT2 and GT3), 10 animals in each group. The control group was kept under observation only. In the treatment groups, physical and memory exercises were applied, and to GT1, only memory exercises; to GT2 climbing stairs, and to GT3 both exercises. Animals that underwent ladder climbing three times a week for three consecutive months and memory tests showed better performance in short and long term memory and habituation as well as lower anxiety in the open field test. The low concentration of malonaldehyde (MDA), the balance of superoxide dismutase (SOD) and the increase in total antioxidant capacity (Ferric Reducing Antioxidant Power - FRAP) were observed in the plasma and hippocampal samples of rats submitted to treatments. Regular exercise practice associated with memory exercises improved mnemonic abilities, decreased oxidative stress and anxiety of rats in senescence.
|
152 |
Model Driven Architecture in Adaptive Library GenerationJimenez Moral, Inmaculada, De Arcayne Mañá, Joan January 2008 (has links)
This master thesis is about building an adaptive library based on a platform independent model, which represents a conceptual design realizing the functional requirements being independent of the technologies and software architectures changes. This adaptive library is a model, which has a higher level of abstraction than the code that we will generate afterwards, generalizes the solution of those problems that can be resolved using different implementations that uses different kinds of data structures. In addition the higher level of abstraction that this adaptive library is having will give a speed up in developing the application and higher quality solution because of the maintainability and reusability. This solution is going to have the propriety to be changed easily in order to solve different concrete problems.
|
153 |
Um Profile UML 2 e um Processo de Desenvolvimento para Engenharia de Interfaces Gráficas Dirigida a Modelos e Baseada em ComponentesFrancisco Buarque de Lacerda Júnior, Luiz January 2007 (has links)
Made available in DSpace on 2014-06-12T16:00:04Z (GMT). No. of bitstreams: 2
arquivo5840_1.pdf: 7751345 bytes, checksum: 6f08e8815bf45fbad5da9a1a2aab748c (MD5)
license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)
Previous issue date: 2007 / Nos últimos anos, com a proliferação das interfaces gráficas do usuário nos mais variados
ambientes computacionais, tornou-se patente a necessidade de uma Engenharia de Interfaces
Gráficas para abarcar as peculiaridades do seu desenvolvimento, peculiaridades estas
que fogem à maior parte das metodologias, linguagens e ferramentas da tradicional Engenharia
de Software.
Buscando enriquecer o conhecimento nesta área, o presente projeto propõe uma extensão
da linguagem UML 2 para a modelagem de interfaces gráficas baseando-se em abordagens
recentes que privilegiam a extensão do UML referência na modelagem de sistemas
de software em detrimento da criação de uma nova linguagem de modelagem.
Propõe também um processo de modelagem de GUI orientado a modelos e baseado
em componentes, que utiliza a extensão do UML proposta e se acopla à metodologia de desenvolvimento
KobrA, orientada modelos, linhas de produto e baseada em componentes
|
154 |
Att konstruera en gemenskap -teori och konstruktion av virtuella samhällenÖsterlund, Mattias January 2000 (has links)
Virtual communities are a phenomenon that is becoming more common as the information technology comes with in reach for the general public. This report will bring the theories and construction of a virtual community together. The purpose of this report is to describe the different theories that have emerged from the research within this field and to examine the work procedures that have been used during the development of a site for a MDA-community. The MDA-website is a homepage on the Internet that was developed to bring the students closer together. The report describes the work of the project group, why the website was not completed and at the end the theories are looked at on the basis of the construction of the website.
|
155 |
Combining Discrete and Continuous Domains for SysML-Based Simulation and Test Generation / Unification des ensembles discrets et continus pour la simulation et la génération de tests à partir de modèles sysMLGauthier, Jean-Marie 19 November 2015 (has links)
Les travaux de recherche menés au cours de cette thèse s'inscrivent dans le cadre de la modélisation, de la vérification et de la validation de systèmes complexes, critiques et multi-physiques. Ces travaux visent à combler l'écart d'abstraction entre les modèles haut-niveau, point de départ des processus MBSE (Model-Based Systems Engineering), et la simulation temps réel, clef de voûte des approches In-the-Loop. Dans ce contexte, nous proposons d'unifier, au sein d'un même modèle SysML, les aspects continus d'un système, permettant de générer de manière automatique un modèle Modelica de plus bas niveau directement exécutable (simulation), et les aspects discrets, permettant l'animation et la génération de tests par des solveurs de contraintes. Les travaux réalisés au cours de cette thèse ont permis l'étude et la réalisation d'une chaîne outillée originale permettant de simuler et de tester ce type de systèmes à partir de modèles SysML en contexte In-the-Loop. Cette démarche a été validée par deux cas d'étude concrets issus de la recherche. Le premier, issu du projet ANR Smart Blocks, nous a permis de mettre à l'épreuve la méthodologie de modélisation SysML dans le but d'effectuer des simulations de convoyeur sans contact (jets d'air). Le second cas d'étude, issu du projet Région GEOSEFA, nous a permis de valider l'approche complète (simulation et test) en contexte In-the-Loop. Celui-ci porte sur la conception et la validation d'un nouveau système énergétique hybride embarqué dans un hélicoptère. / The research conducted during this thesis fall within the scope of modeling, verification and validation of critical and complex systems. This work aims to bridge the gap between the abstract high-level models, starting point of the MBSE process (Model-Based Systems Engineering), and real-time simulation keystone of In-the-Loop processes. In this context, we propose to unify, within a SysML model, continuous aspects of a system, to automatically generate an executable Modelica model (simulation), and discrete aspects allowing animation and test generation by constraint solvers. The work done during this thesis allowed the study and the realization of an original tooled approach to simulate and test such systems from SysML models within a In-the-Loop context. This approach has been validated by two concrete case studies from research partners. The first, from the ANR Smart Blocks project, allowed us to assess the relevance of the proposed SysML modeling methodology in order to perform contact less conveyor simulations. The second case study, from the GEOSEFA Regional project has allowed us to validate the overall approach (simulation and testing) in a In-the-Loop context. It covers the design and the validation of a new energy hybrid system embedded in a helicopter.
|
156 |
Herzberg's Motivation Factors in A Gamification Environment : How motivational factors may be applied to game design in order to describe the experience of a serious gameDahlberg, Rikard January 2015 (has links)
This paper is aimed to analyze how the Motivators in Herzberg's Two-Factor theory can be applied to a game design framework, namely the MDA-framework. This is done by evaluating a feature called Detailed Feedback System which is a gamification layer aimed towards evaluating photos from predetermined categories. The evaluation is done by letting participants use the Detailed Feedback System, and later letting them participate in an online survey on how it felt to use the feature. In this paper Self-Determination Theory and the Likert-scale is used in order to find a variance in their answers. This is later explored in a comparison matrix exploring which aspects of each theoretical framework may be the most prominent. The results are also analyzed to find variance in the final result, in order to find how significant the variance is in motivation and enjoyment, and why I conclude these findings to be positive.
|
157 |
Humour as a postcolonial strategy in Zakes Mda's novel, The heart of rednessHagemann, Michael Eric January 2005 (has links)
Magister Artium - MA / This thesis sought to demonstrate that humour and the grotesque are the primary tools by which Mda achieve his postcolonial strategies of "writing back" that is, of asserting an identity in the face of colonial pressures, apartheid and the growing selfishness of many in the new, post-democratic South African society. / South Africa
|
158 |
Transformace konceptuálních modelů do realizace informačního systému / Transformation of conceptual models into the information systems implementationVagner, Vlastimil January 2010 (has links)
This thesis deals with the linkages between data models from conceptual models to physical design of information bases, used for implementation. The aim is to analyze the modern approach to design systems and specify how detailed the conceptual modeling and impact on the quality of the final form of application or system, including processes that take place in advance to the next level of design. Approximated the techniques the transition between these levels and will take into account structural features and limitations of selected platforms and requirements for their design and mutual coherence level view of the system. For the purpose of the thesis the well known data modeling methods are being analyzed together with their applicabilities.
|
159 |
Hopelessness in Video Games : Motivating the playerÖgren, Erik January 2020 (has links)
This bachelor thesis details the study and analysis of hopelessness, motivation, and personality types concerning game design. It offers definitions for hopelessness based on previous studies and explains what makes people experience hopelessness in games. The thesis compares previously conducted studies on hopelessness and motivation, confirms their validity, and applies the conclusion to theories of game design, such as MDA.
|
160 |
Evoluce a integrace XML formátů / XML Formats Evolution and IntegrationKlímek, Jakub January 2013 (has links)
In the past decade XML became a wide-spread information exchange data model. Many XML users have many XML formats described by XML schemas. To ease the management of multiple XML schemas modeling similar reality, the conceptual model for XML was defined. With its definition came various challenges that needed to be further researched. This thesis focuses on two of those challenges. The first challenge is to manage the evolution of the multi-level conceptual model as the modeled reality, XML schemas and applications evolve in time. The second challenge is to allow the majority of users who already use XML schemas in their system without the conceptual model to use their schemas to semi-automatically create one. In addition a step towards integration of the conceptual modeling of XML and semantic web techniques was taken.
|
Page generated in 0.0386 seconds