Etude des propriétés de symétrie des solutions de quelques problèmes aux limites de type elliptique. / Doctorat en sciences, Spécialisation mathématiques / info:eu-repo/semantics/nonPublished

In Chapter 1, the staggered nature of the adoption of interstate bank branching deregulation in the United States is utilized as an exogeneous shock to investigate the managerial incentives involved in corporate socially responsible (CSR) activities. Using Kinder, Lydenberg, and Domini Research & Analytics, Inc. for our CSR measures, we find a significant negative relation between the extent of deregulation and CSR practices, which implies that deregulation-led rising competition in product market makes the non-financial firms more concerned about protecting interests of shareholders than other stakeholders. Specifically, firms with low pricing power tend to significantly reduce their CSR activities. Our results are robust using alternative empirical specifications and CSR measures. Chapter 2 investigates the interaction between price stability and financial stability for “Fragile Five” countries. In the first step, we investigate the causation linkage between price stability and financial stability indicators. In the second step, we analyze the effect of financial stability instruments, lending rate and required reserve ratio, on price stability. We then test the price stability instrument policy rate on financial stability. Empirical findings, in the first step, indicate that there is no meaningful relationship between policy objectives in the short run, while the relation between financial stability and price stability occurs in the longer time frequencies. However, the situation is not valid for all economies. In the second step, we measure the effects of monetary policy tools employed by the central bank of each of the Fragile Five countries. The findings from the analysis that investigates the effects of each policy instrument imply that the policy rate instrument implemented to achieve the inflation target does not affect the financial stability goal. Similarly, the reserve requirement ratio instrument to achieve the financial stability goal does not affect the price stability goal. On the other hand, results give some implication about the negative effects of the lending rate instrument on the inflation targeting objective.

Le syndrome de Schwartz-Jampel (SJS) est une pathologie autosomique récessive rare car seulement plus de 100 cas ont été décrits dans la littérature. Elle est caractérisée par une raideur musculaire permanente et généralisée associée à une chondrodystrophie. Elle est due à des mutations perte de fonction dans le gène HSPG2 codant pour le perlecan, un héparane sulfate protéoglycane ubiquitaire présent dans les membranes basales et les matrices extracellulaires. Une autre pathologie, la dysplasie dissegmentaire de type Silvermann-Handmaker (DDSH) est due à des mutations perte de fonction dans ce gène, et est caractérisée par une chondrodysplasie très sévère menant à la mort du patient dès les premiers jours de vie. Dans une première partie de mon introduction, je décrirai les signes cliniques de ces deux pathologies et les mutations du gène HSPG2 actuellement connues pour chacune. Le perlecan est une des plus grandes protéines connues. Avec une séquence protéique de plus de 4300 acides aminés et un poids moléculaire de plus de 450kDa, il subit des modifications post-traductionnelles et peut alors atteindre un poids moléculaire de 800kDa. Cette protéine immense assure de multiples interactions et fonctions dans les membranes basales dans lesquelles elle est ubiquitairement présente. Afin de mieux comprendre quel rôle cette protéine peut jouer dans la détermination du phénotype dans le SJS, je détaillerai dans une seconde partie les différentes molécules avec lesquelles le perlecan interagit et les fonctions qu'il assume dans les deux principaux tissus d'intérêt de la pathologie : le cartilage et le muscle. Enfin, je décrirai le phénotype de mutants d'orthologues de gène HSPG2 dans les trois organismes modèles que sont la drosophile, le nématode et la souris. Au cours de ma thèse, je me suis plus particulièrement intéressée au phénotype neuromusculaire du SJS. Pour une meilleure compréhension de mes travaux, je rappellerai dans une troisième et dernière partie de mon introduction, la structure, le développement et le fonctionnement de la jonction neuromusculaire, ainsi que les pathologies humaines congénitales associées.

No description available.

<p>In this thesis report we conducted research study on driver's behavior in T-Intersections using simulated environment. This report describes and discusses correlation analysis of driver's personality traits and style while driving at T-Intersections.</p><p>The experiments were performed on multi user driving simulator under controlled settings, at Linköping University. A total of forty-eight people participated in the study and were divided into groups of four, all driving in the same simulated world.</p><p>During the experiments participants were asked to fill a series of well-known self-report questionnaires. We evaluated questionnaires to get the insight in driver's personality traits and driving style. The self-report questionnaires consist of Schwartz's configural model of 10 values types and NEO-five factor inventory. Also driver's behavior was studied with the help of questionnaires based on driver's behavior, style, conflict avoidance, time horizon and tolerance of uncertainty. Then these 10 Schwartz's values are correlated with the other questionnaires to give the detail insight of the driving habits and personality traits of the drivers.</p>

Title from first page of PDF document. Includes bibliographical references (p. 61-64).

This dissertation combines performance analysis, rhetorical criticism, and psychoanalytical theory to analyze three performance “texts” as sites of haunting in post-9/11 America: Tony Kushner’s 2001 U.S. debut of Homebody/Kabul, the Broadway musical Wicked, and ABC’s television drama Lost. It contributes a nuanced, theorized reading of the civil implications of post-9/11 popular American culture as “more than memory” by demonstrating how these performances suggested “what might be” in ways that subverted Bush’s responses to the attacks. The first chapter reads Homebody/Kabul against the national addresses delivered by Bush in the first weeks after the attacks and argue that the 2001 New York Theatre Workshop performance created a space for audiences to reconsider the version of “mourning” encouraged by the Bush administration. The type of mourning modeled/enabled by Homebody/Kabul, I assert, is different from that against which Derrida warns. Rather than “silencing ghosts” (Gunn 82) through the integration of loss, Homebody/Kabul makes a space for conversing with, and models living with, ghosts. The second chapter argues that the Wicked’s Ozians are stuck in a state of melancholia, refusing to speak to/with the ghost of Elphaba. Because they refuse to reckon with Elphaba, they literally finish exactly where they began—with “No One Mourn[ing] the Wicked.” By reading Wicked against the celebratory rhetoric of the Bush administration after declaring “Mission Accomplished” in Iraq, we can understand the way the United States as a nation was (and may still be, in 2010) haunted by the Bush administration's failure to lead the nation in mourning effectively and ethically and by its incessant rhetoric of evil. The third chapter advocates for Lost as a hauntological reckoning with 9/11 that models ethical witnessing as a potentially generative meeting of human beings across cultures at the site of trauma. An alternative to the fear that the Bush administration encouraged leading up to Lost’s premiere and through its final season, ethical witnessing as modeled on Lost suggests that civilization stands to thrive where difference is honored—and risks toppling into chaos where the alternative “us against them” mentality (Other anxiety) prevails. / text

Studiens övergripande syfte är att undersöka sambanden mellan grundläggande värderingar, arbetssituation och arbetstillfredsställelse. De konkreta frågeställningarna är 1. Finns det något direkt samband mellan fem grundläggande värderingar och arbetstillfredsställelse? 2. Finns det ett samspel mellan grundläggande värderingar, arbetssituation och arbetstillfredsställelse? Undersökningens primära fokus är frågeställnigen 2. Det är en kvantitativ undersökning där multipel regressionsanalys används. Datamaterialet är hämtat från ESS (2010). Den beroende variabeln är arbetstillfredsställelse, de oberoende variablerna är fem grundläggande värderingar såsom självstyrning, stimulans, prestation, makt, trygghet och arbetssituation såsom autonomi i arbetet, varierande/utvecklande arbete, karriärmöjligheter, möjlighet att påverka beslut och anställningstrygghet. När det gäller frågeställning 1värderingarnas direkta betydelse för arbetstillfredsställelsenså visar de viktigaste resultaten på att det finns ett positivt samband mellan både självstyrning, stimulans och arbetstillfredsställelse. Men att värderingarna prestation, makt och trygghet däremot har en negativ effekt på arbetstillfredsställelse, d.v.s. dessa värderingar leder till en mindre tillfredställelse med arbetet. När det gäller frågeställning 2, värderingarnas samspel med arbetssituation och indirekta samband med arbetstillfredställelse, visar resultaten på att arbetstillfredsställelsen överlag ökar när man matchar personliga värderingar med en liknande arbetssituation. Framförallt gäller detta värderingar prestation, makt och trygghet.En tolkning av detta kan vara att dessa värderingar, enligt Schwartz, bygger på ängslan och är socialt orienterade, vilket då skulle kunna innebära att när man matchar dessa värderingar med en liknande arbetssituation så reduceras ängslan och det sociala samspelet individ (värdering) och miljö (arbetssituation) får därmed en extra tydlig positiv betydelse för arbetstillfredsställelsen. Personliga värderingar i sig själv har inte något entydigt samband med arbetstillfredsställelse, utan det är framförallt när en person ha rett arbete som överensstämmer med de egna värderingarna som arbetstillfredsställelsen ökar.

Chapter 2 of the thesis describes a highly efficient in situ method for the reduction of amides to aldehydes and aryl O-carbamates to phenols and other transformations involving hydrozirconations. The method, as a three-component-type reaction, involves in situ generation of the Schwartz reagent (Cp2Zr(H)Cl) from Cp2ZrCl2 and the reductant, LiAlH(O-t-Bu)3, and immediate reaction with a substrate. Substrates include aliphatic and aromatic tertiary amides which are reduced to aldehydes, aryl O-carbamates which are reduced to phenols, and alkynes which undergo other transformations via hydrozirconation. Compared to prior methods, this method has advantage in that reagents are inexpensive and stable, reaction times are short, and reaction temperatures are generally conveniently at room temperature. The use of the in situ method described herein instead of the requirement for the synthesis of the commercially available Schwartz reagent is estimated to provide more than 50% reduction in cost. Chapter 3 of the thesis describes the discovery and development of efficient and regioselective Ru-catalyzed amide-directed C-H, C-N, C-O activation/C-C bond forming reactions, ester-directed C-O activation/C-C bond forming reaction, and amide-directed C-O activation/hydrodemethoxylation reactions under a simple RuH2(CO)(PPh3)3/toluene catalytic system. Of these, the amide-directed C-H activation/cross coupling reaction proceeds well but uniquely on furan 3-amide substrates while the ester-directed C-O activation is effective on the 2-MeO-1-naphthoic acid methyl ester. On the other hand, the amide-directed C-N and C-O activation/coupling reactions are broadly applicable on benzamides and naphthamides. All of these achievements of directed C-H, C-N, C-O activation/coupling reactions complement and may supercede the DoM (directed ortho metalation)-cross coupling strategy, and establish the catalytic base-free DoM-cross coupling process at non-cryogenic temperature as a convenient, economical and green alternative. The new catalytic amide-directed ortho-hydrodemethoxylation reaction has potential value in links to aromatic electrophilic substitution and DoM chemistries. Furthermore, a new borylation reaction via Ru-catalyzed amide-directed C-H activation/C-B bond forming process is also reported herein. / Thesis (Ph.D, Chemistry) -- Queen's University, 2010-12-21 11:12:35.564

Dans cette thèse j’étudie l’impact de la géométrie de micro et nano-domaines biologiques sur les propriétés d'électrodiffusion, ceci à l'aide des équations aux dérivées partielles de Poisson-Nernst-Planck. Je considère des domaines non-triviaux ayant une forme cuspide ou elliptique. Mon objectif est de développer des modèles ainsi que des méthodes mathématiques afin d'étudier les caractéristiques électriques de ces nano/micro-domaines, et ainsi mieux comprendre comment les signaux électriques sont modulés à ces échelles. Dans la première partie j’étudie le voltage à l'équilibre pour un électrolyte dans un domaine borné, et ayant un fort excès de charges positives. Je montre que le premier temps de sortie dans une boule chargée dépend de la surface et non du volume. J’étudie ensuite la géométrie composées d'une boule à laquelle est attachée un domaine cuspide. Je construis ensuite une solution asymptotique pour le voltage dans les cas 2D et 3D et je montre qu’ils sont donnés au premier ordre par la même expression. Enfin, j’obtiens la même conclusion en considérant une géométrie formée d'une ellipse, dont je construis une solution asymptotique du voltage en 2D et 3D. La seconde partie porte sur la modélisation de la compartimentalisation électrique des épines dendritiques. A partir de simulations numériques, je mets en évidence le lien entre la polarisation de concentration dans l'épine et sa géométrie. Je compare ensuite mon modèle à des données de microscopie. Je développe une méthode de déconvolution pour extraire la dynamique rapide du voltage à partir des données de microscopie. Enfin j’estime la résistance du cou et montre que celle-ci ne suit pas la loi d'Ohm. / In this PhD I study how electro-diffusion within biological micro and nano-domains is affected by their shapes using the Poisson-Nernst-Planck (PNP) partial differential equations. I consider non-trivial shapes such as domains with cusp and ellipses. Our goal is to develop models, as well as mathematical tools, to study the electrical properties of micro and nano-domains, to understand better how electrical neuronal signaling is regulated at those scales. In the first part I estimate the steady-state voltage inside an electrolyte confined in a bounded domain, within which we assume an excess of positive charge. I show the mean first passage time in a charged ball depends on the surface and not on the volume. I further study a geometry composed of a ball with an attached cusp-shaped domain. I construct an asymptotic solution for the voltage in 2D and 3D and I show that to leading order expressions for the voltage in 2D and 3D are identical. Finally, I obtain similar conclusion considering an elliptical-shaped domain for which I construct an asymptotic solution for the voltage in 2D and 3D. In the second part, I model the electrical compartmentalization in dendritic spines. Based on numerical simulations, I show how spines non-cylindrical geometry leads to concentration polarization effects. I then compare my model to experimental data of microscopy imaging. I develop a deconvolution method to recover the fast voltage dynamic from the data. I estimate the neck resistance, and we found that, contrary to Ohm's law, the spine neck resistance can be inversely proportional to its radius.