Bakgrund: Varje år föds det 15 miljoner prematura barn i världen. Prematura barn behöver vårdas på en neonatalavdelning, tills de är friska nog att lämna avdelningen. I familjecentrerad omvårdnad betraktas familjen som en helhet. Familjecentrering är ett relativt nytt forskningsområde, med perspektiv från både föräldrar och vårdpersonal. Tidigare forskning inom familjecentrerad omvårdnad på en neonatalavdelning visar på positiva effekter hos både förälder och barn. Syfte: Syftet var att belysa föräldrars upplevelse av familjecentrerad omvårdnad på en neonatalavdelning. Metod: Studien var en litteraturöversikt som inkluderade 15 vetenskapliga artiklar på engelska som var publicerade mellan år 2010 och 2020. Både kvalitativa och kvantitativa artiklar inkluderades i studien. Databassökningen skedde i databaserna CINAHL och PubMed och artiklarna analyserades i enlighet med Kristenssons (2014) integrerade analys. Resultat: Resultatet visade att många föräldrar upplever tiden på neonatalavdelningen som en känslomässig berg- och dalbana. Många föräldrar längtade efter närhet med deras barn, oftast var hindret till närhet en rädsla för att barnets hälsa skulle försämras. Vägledning visade sig ge föräldrarna modet att delta i omvårdanden med deras barn, och även möjlighet till att knyta an till barnet. Sjuksköterskan var ett stort stöd enligt föräldrarna, även bara att vara i närheten gav familjen en möjlighet till att slappna av. Slutsats: Föräldrar som får ett prematurt barn överväldigas av många olika känslor. Vårdpersonalen på neonatalavdelningen bidrar till stöd och vägledning. Upplevelser som var återkommande hos föräldrarna var att deras stress minskade när de fick vara med sitt barn samt vara delaktig i vården. Som sjuksköterska är kunskap om hur man ska stötta och bemöta föräldrar i denna sårbara situation betydelsefull för att kunna möjliggöra en så bra och individanpassad vård som möjligt. / Background: Every year 15 million premature children are born. Premature children are in need of care in a neonatal intensive care unit, until they are strong enough to be discharged. In family centered care (FCC) the family is viewed as an ensemble. FCC is a relatively new research area, with perspectives both from parents and health personnel. Research has shown that FCC had positive effects on both parents and child in a neonatal intensive care unit (NICU). Aim: The aim was to describe parent’s experiences of FCC in NICU.  Method: The study was a literature review that included 15 scientific articles in English, which were published between the years 2010 and 2020. Both qualitative and quantitative articles were included. The database search was made in CINAHL and PubMed and the articles were analysed according to Kristensson’s (2014) integrated analysis. Results: The results showed that many parents experience the time in NICU as an emotional roller-coaster. Many parents long for a physical contact with their child, often the fear of the child's health is an obstacle. Guidance showed that parents had the courage to participate in their child's care and got the opportunity of getting an emotional connection. The nurse was a big support for the parents, to be nearby gave the family the opportunity to relax more. Conclusions: Parents that give birth to a premature child gets overwhelmed with different feelings. The health personnel in the NICU contributes to support and guidance. Experiences that was repetitive were that parents stress decreased when they were able to be with their child and to participate in the care of their child. As a nurse knowledge of how you are going to support and meet parents in this vulnerable situation is significant to make it possible for a good and an individualized care.

Bakgrund Tidigt föräldraskap redan på neonatalvårdsavdelning med aktivt deltagande och hud-mothudkontakt påvisar positiva effekter hos det prematura barnet och främjar en sund anknytning. För att främja deltagande behövs ett respektfullt samarbete mellan sjuksköterska och familj enligt familjecentrerad vård (FCC). Syfte Syftet var att sammanställa tidigare forskning för att beskriva föräldrars upplevelser av delaktighet i omvårdnaden av prematura barn. Metod Litteraturstudien inkluderade 15 studier med kvalitativ design och utformades som en strukturerad litteraturstudie. Datainsamlingen utfördes i databaserna PubMed och CINAHL. Inför inklusion lästes artiklarna av båda författarna och kvalitetsgranskades enligt Fribergs granskningsfrågor för kvalitativa studier. Dataanalys utfördes strukturerat utifrån Fribergs fyra steg för att analysera och sammanställa resultatet. Resultat Två kategorier med respektive sex underkategorier identifierades där främjande respektive hindrande faktorer av föräldrars upplevelser av delaktighet speglas. Att vara närvarande i omvårdnaden samt hud-mot-hudkontakt med barnet fick föräldrarna att känna sig delaktiga. Stöd och vägledning från vårdpersonal hade stor betydelse och upplevdes underlättade för föräldrarna. Det fanns känslomässiga hinder för anknytningen samt svårigheter med miljöns utformning. Slutsats Delaktigheten i omvårdnaden var viktigt för att gynna amningen, stärka föräldrarollen samt öka självförtroendet och kan uppnås med implementering av FFC. / Background Early parenthood already in the neonatal care unit with active participation and skin-to-skin contact demonstrates positive effects in the premature baby and promotes a healthy bonding. To promote participation, a respectful collaboration between nurse and family is needed according to family-centered care (FCC). Aim The aim of this study was to compile previous research to describe parents' experiences of participation in the care of premature infants. Method The literature review included 15 studies with qualitative design and was designed as a structured literature review. The data collection was performed in the databases PubMed and CINAHL. Prior to inclusion, the articles were read by both authors and quality reviewed according to Friberg's review questions for qualitative studies. Data analysis was performed in a structured way based on Friberg's four steps to analyze and set the results. Results Two categories with six subcategories were identified where promoting and barrier factors of parents' experiences of participation are reflected. Being present in the care and skin-to-skin contact with the child made the parents feel involved. Support and guidance from healthcare professionals was of great importance and was perceived as easier for the parents. There were emotional barriers to the connection as well as difficulties with the design of the environment. Conclusions Participation in nursing was important to promote breastfeeding, strengthen the parental role and increase self-confidence and can be achieved with the implementation of FCC.

Preterm birth disrupts the development of the brain and other critical organs of the infant body. Since the brain is one of the last organs to finish developing during pregnancy, the risk for substantial neurological deficits increases as the gestational age decreases. One way to combat these deficits is to reconnect the preterm infant with the mother via skin-to-skin contact, also known as kangaroo care (KC). This intimate touch helps to replicate aspects of the environment that the preterm infant experienced in utero. The purpose of this literature review was to analyze the current literature to better understand the effects that KC may have on facilitating neurodevelopment of preterm infants in Neonatal Intensive Care Units (NICUs). Emphasis was placed on neurophysiologic functioning, autonomic functioning, and neurobehavioral functioning. A database search of CINAHL Plus with Full Text, PsycINFO, MEDLINE, Cochrane Central Register of Controlled Trials, and Health Source: Nursing/Academic Edition was conducted, and a total of six articles were reviewed based on their relevance and application towards this thesis. KC is a low-cost, relatively easy intervention to initiate that can have positive impacts on many aspects of preterm infant growth and maturation. There is limited research regarding the use of KC as an intervention to support neurodevelopment, especially with regards to long-term effects. Existing research supports the use of KC as an intervention to facilitate neurodevelopment in preterm infants in the NICU.

The purpose of this study was to conduct an integrated review of the literature examining the use of non-pharmacologic pain management strategies in premature neonates and to explore the relationship between health outcomes and time to discharge from the neonatal intensive care unit (NICU). Non-pharmacologic pain management strategies include human touch, facilitated tucking, non-nutritive sucking, and kangaroo care. A systematic review of the literature was conducted from multiple online databases. Peer reviewed, English-language articles containing the keywords ‘pain management’, ‘neonatal intensive care unit’, and ‘non-pharmacologic’ were included for synthesis. Exclusion criteria included articles with a focus on infants not admitted to the NICU and infants with a gestational age greater than 37 weeks. Results revealed positive outcomes when alternative pain-relieving methods, rather than drug therapy, were used in the NICU. A majority of articles suggest facilitated tucking is very successful in lowering a preterm infant’s pain. However, facilitated tucking alone was significantly less effective in relieving procedural pain compared to facilitated tucking in combination with oral sucrose administration. Kangaroo care and gentle human touch also proved to reduce physiologic and behavioral signs of pain in neonates. The literature reveled an overall positive outcome when non-pharmacologic pain interventions are used in the NICU, with some behavioral interventions showing better efficacy than others at relieving neonatal pain. None of the reviewed articles explored the relationship between reduced length of stay and parameters assessing health outcomes based on pain control in neonates. The literature indicated nurses play a significant role in the use of pain-relieving methods in neonatal populations. Implications for future research that focuses on successful behavioral based pain management strategies that assists in refining neonatal pain relief would be of great benefit to improving health outcomes related to infant survival after discharge from the NICU.

No description available.

Este estudo teve como trajetória desvelar o fenômeno: enfermeira no cuidado ao recém-nascido e aos seus pais na Unidade de Terapia Intensiva Neonatal (UTIn), e a sua ação na formação de vínculo afetivo. Para tanto, objetivou: conhecer a vivência da enfermeira no cuidado ao recém-nascido e aos seus pais na UTIn; compreender como as enfermeiras vivenciam o processo de vínculo afetivo entre recém-nascidos internados em UTIn e seus pais, e apreender o típico da vivência das enfermeiras em ações que envolvem este cuidado. Com tal proposta, optou-se por realizar uma pesquisa qualitativa, segundo a abordagem da fenomenologia social, com base nas questões norteadoras: Como você, enfermeira, vivencia o cuidado ao recém-nascido na UTIn e aos seus pais? O que você espera com o seu atendimento? Dos discursos das enfermeiras, identificou-se categorias concretas do vivido, que expressam aspectos significativos da vivência, considerando os motivos por que e os motivos para que determinam a relação de suas ações e que foram interpretadas, segundo o referencial de Alfred Schütz. Por meio da análise dessas categorias, chegou-se ao tipo vivido do grupo social \"enfermeira que atua em UTIn junto aos recém-nascidos e aos seus pais\" como sendo: aquela que é competente técnica e cientificamente no cuidado ao recém-nascido de risco, prioriza o cuidado em rotinas e protocolos, mas sente-se despreparada para lidar com os pais dos neonatos. Devido a esse contexto, percebe-se a necessidade de aprimorar seus conhecimentos sobre humanização e relações humanas, para poder informar e preparar esses pais sobre o ambiente, equipamentos da UTIn, a fim de que possam continuar o cuidado ao filho em casa e, conseqüentemente, conquistar a valorização e a confiança desses pais. Reconhece ser o elo de aproximação entre eles, ajudando-os, juntamente com a instituição, a aceitarem e a conviverem com o filho internado, favorecendo, assim, a formação do vínculo afetivo. A Sociologia Fenomenológica de Alfred Schütz possibilitou a compreensão dos motivos existenciais que apontam para um cuidar mais humanizado aos recém-nascidos internados na UTIn e aos seus pais, por meio de aprimoramento, informação e preparo, conquista do reconhecimento e confiança desses pais e ações que promovam o contato humano, favorecendo a formação de vínculo afetivo entre pais e filhos / The trajectory of this study was to unveil the phenomenon: nurse in care for newborn infants and their parents at the Neonatal Intensive Care Unit (NICU), and her action in affective bonding. Therefore, the goal was to: get to know the nurse\'s experience in care delivery to newborn infants and their parents at the NICU; understand how the nurses experience the affective bonding process between newborn infants hospitalized at the NICU and their parents, and to apprehend what is typical about the nurses\' experience in actions involving this care. With this goal, a qualitative design was chosen, according to the social phenomenology approach, based on the following guiding questions: How do you, nurse, experience care delivery to newborn infants at the NICU and their parents? What do you expect to achieve through your care? Based on the nurses\' discourse, concrete categories were identified, which express significant aspects of the experience, considering the reasons why and the reasons for that determine the relation among their actions and that were interpreted according to the reference framework of Alfred Schütz. The analysis of these categories led to the type experienced by the social group \"nurse in care for newborn infants and their parents at the Neonatal Intensive Care Unit\" as: technically and scientifically competent in care for newborn infants at risk, prioritizes care in routines and protocols, but feels unprepared to deal with the newborns\' parents. Due to this context, the need is perceived to improve their knowledge about humanization and human relations, to be able to prepare and inform these parents about the environment, NICU equipment, so that they can continue care for their child at home and, consequently, conquer these parents\' valuation and trust. The nurse is acknowledged as the link that approximates them, helping them, together with the institution, to accept and to live with their hospitalized child, thus favoring affective bonding. Alfred Schütz\' Phenomenological Sociology made it possible to understand the existential reasons that point towards a more humanized care for newborn infants at the NICU and for their parents, through continuing education, information and preparation, conquest of these parents\' acknowledgement and trust and actions that promote human contact, thus favoring affective bonding between parents and children

Introdução: As infecções relacionadas à assistência à saúde (IRAS) estão entre as principais causas de morte e aumento de estados de morbidez em doentes hospitalizados. Os recém-nascidos são suscetíveis a infecção, pois seus mecanismos de defesa ainda não estão maduros e ocupam um ambiente em que antibióticos e procedimentos invasivos são freqüentes. As mãos são consideradas as principais vias de disseminação de IRAS e a eficaz higienização é a medida importante para evitar as infecções. A capacitação e educação permanente dos profissionais de saúde são ferramentas essenciais para a construção de resultados positivos e o ambiente simulada desponta como estratégia pedagógica. Objetivo: Avaliar a efetividade de uma intervenção educativa em cenário simulado no aumento da adesão à higiene das mãos pela equipe de enfermagem e na redução das IRAS em uma Unidade de Terapia Intensiva Neonatal (UTIN). Método: Estudo quase-experimental, com abordagem quantitativa, que incluiu todos os profissionais de enfermagem da UTIN de um hospital universitário terciário no interior paulista. A pesquisa foi aprovada por Comitê de Ética em Pesquisa e desenvolvida em três etapas, incluindo a avaliação da adesão à higienização das mãos conforme os cinco momentos recomendados pela Organização Mundial da Saúde (OMS), antes e após intervenção educativa em cenário simulado com casos clínicos contextualizados com a realidade do serviço. As taxas de IRAS foram computadas em uma série histórica de 35 meses, sendo apenas o último mês no pós intervenção. Os dados foram analisados pelo programa STATA, com uso de estatística descritiva. Resultados: Na etapa pré intervenção, os profissionais realizaram a higiene das mãos em 41,2% das vezes, valor que aumentou após a simulação para 59,7% de ações realizadas conforme indicação. A técnica executada para higiene das mãos aumentou de 76,6% para 85,2% de conformidade após intervenção. A higiene das unhas e extremidades ainda é a maior fragilidade dos participantes na execução da técnica. Todas as categorias profissionais tiveram aumento entre 17 a 19% na adesão à higienização das mãos, com significância estatística na comparação pré e pós intervenção: p<0,001 para enfermeiros e técnicos de enfermagem; p=0,005 para auxiliares de enfermagem. Na análise da higiene das mãos, em três dentre os cinco momentos recomendados pela OMS as médias de adesão aumentaram significativamente, sendo antes (p<0,001) e após (p=0,008) o contato com o RN e após o contato com superfícies (p<0,001). As médias de adesão antes do procedimento asséptico (de 57,6% para 72,7%) e após exposição a fluídos (de 77,3% para 95,5%) aumentaram, apesar de não haver significância estatística. A taxa de IRAS no mês subsequente a intervenção (8,5%) não decresceu em comparação ao mês anterior a intervenção (7,8%), sendo que tais taxas foram relativamente inferiores em 19 dos 35 meses de coleta. Conclusão: Confirma-se a hipótese primária que a taxa de adesão à higiene das mãos pela equipe de enfermagem aumentou após a intervenção educativa em cenário simulado, em comparação com a taxa antes da intervenção, todavia, rejeitase a hipótese secundária, pois a taxa de IRAS não reduziu no mês subseqüente a intervenção educativa, em comparação com a taxa no mês pré intervenção / Background:The infections acquired in healthcare environments not only increase morbidity in hospitalized patientsbut also causea great number of deaths. Newborns (NBs) are susceptible to infection due to their immature defense mechanisms allied to the high frequency of antibiotics prescription and invasive procedures. As hands are considered the key dissemination pathway of healthcare-associated infections (HAI), the effective hand hygiene compliance is the most important measure to prevent infections. Healthcare professionals training and permanent education, mainly those based on simulation strategies, are essential tools to achieveour main goal, that is healthcare associated infections control.Objective:To evaluate the effectiveness of an educational intervention, in a simulated scenario, in the increase of hand hygiene adherence by the nursing team and in the reduction of HAI in a Neonatal Intensive Care Unit (NICU).Method:Quasi-experimental study with a quantitative approach including all nursing professionals at the NICU of a tertiary university hospital in the countryside of the São PauloState. After the approval by the Ethics Research Committee, the study was developed in three phases, including the evaluation of hand hygiene adherence in a simulation setting according to the five moments recommended by WHO, before and after the educational intervention, based on local clinical cases. HAI rates have been computed in a historical series of the 35 months, being only last month in post-intervention. Data were analyzed using the software STATA, using descriptivestatistics.Results: In the pre-intervention phase, the professionalsperformedhand hygiene in 41,2% of times,which increased after simulation, with 59.7% of actions performed as indicated.In relation to the technique employed for hand hygiene, it moved from 76.6% to 85.2% of conformance after intervention. Thehygiene of nails and extremitiesis still the greatest fragility of the participants performing the technique. All professionals categories had between 17 to 19% of increasing the hand hygiene compliance, with statistical significance in the pre and post intervention comparison: p<0,001 for nurses and nursing technicians; p=0,005 for nursing assistant. The analysis of the hand hygiene in three out of the five moments recommended by WHO,showed that the average of adherence significantly increased, being before (p<0,001) and after (p=0,008) the contact with NBs and after the contact with surfaces (p<0,001). The averages of adherence before aseptic procedure (57,6% to 72,7%) and after exposure to fluids (77,3% to 95,5%) increased, however without statistical significance.The HAI rates in the following month of intervention (8,5%) did not drop compared to the month before the intervention (7,8%), and these rates were relatively lower in 19 out of the 35 months of data collect. Conclusion: The primary hypothesis was confirmed, as the adherence hand hygiene through the nursing team increased post educational intervention in simulated scenario, in comparison with the rates before the intervention. However, the secondary hypothesis was rejected, because the HAI rates did not reduced in the following month of educational intervention, in comparison with the rates in the pre-intervention month

O objetivo desta dissertação foi descrever a investigação de um surto de Klebsiella pneumoniae em uma unidade de terapia intensiva neonatal cujo elo entre os casos foi a mão, persistentemente colonizada pelo agente, de uma técnica de enfermagem que apresentava onicomicose em primeiro quirodáctilo esquerdo. Revisou-se a história da aplicação do método epidemiológico na investigação de surtos de infecção relacionada à assistência à saúde. Foi revisada também a literatura pertinente à investigação de surtos na busca de situações semelhantes. Embora seja bem conhecido o papel das mãos de profissional de saúde na transmissão cruzada de agentes causadores de infecção nosocomial, poucos surtos foram publicados em que estes profissionais atuaram como fonte comum e persistente de infecção. É mais freqüente Gram-positivos envolvidos, havendo cinco relatos de Gram-negativos neste contexto. A contribuição desta dissertação é alertar para o risco que profissionais de saúde com alterações tróficas em mãos e anexos podem representar quando atuam em unidades críticas de assistência, assim como durante investigações de surto em que a evidências apontam para uma fonte comum, a busca de profissional com tais alterações deve ser considerada / The aim of this study was to describe the investigation of an outbreak of Klebsiella pneumoniae at a neonatal intensive care unit, associated with the persistently colonized hands of a nurse who had onychomycosis on her left thumb. We reviewed the use of the epidemiological method for investigating healthcare related outbreaks of infections. We also reviewed the literature concerning the hands of health care personnel. Although the hands of healthcare workers (HCW) play a role in the cross-transmission of nosocomial pathogens, there are few reports in which the persistently colonized hands act as a common source perpetuating an outbreak. In this setting, Gram-positive outbreaks are frequently reported and five Gramnegative outbreaks were reported. By means of this work, we have sought to draw attention to the role of the healthcare professional with chronic lesions on the hand skin and/or fingernails. They may pose a risk of persistent transmission of nosocomial pathogens, especially for critical patients with invasive devices. During healthcare infection outbreaks, examination of the hands of HCW should be included in the investigation

Made available in DSpace on 2016-08-10T10:53:45Z (GMT). No. of bitstreams: 1 GABRIELA CARDOSO MOREIRA MARQUES.pdf: 1903683 bytes, checksum: 6c486d333c5cf2306942aa9b630124c6 (MD5) Previous issue date: 2013-03-05 / Breastfeeding is recognized as a priority of public health policy in reducing perinatal and infant mortality. However, despite programs encourage breastfeeding, its implementation occurs in Brazil substandard. It´s a descriptive qualitative study with phenomenological approach and aims at understanding the meaning of the use of exclusive breastfeeding to mothers who had their babies admitted to the Neonatal Intensive Care Unit. Data were collected from July 2011 to July 2012, through semistructured interviews with mothers. Observation was used to achieve or seek further the essence of the information regarding the phenomenon. In discourse analysis, four categories emerged: maternal instinct and common sense in breastfeeding, breastfeeding important act of love; Motivation to continue or abandon breastfeeding; Influences of (mis) understanding of information regarding breastfeeding. Results: The study revealed the suffering, the pain, the anguish and the frustration, feelings that can be minimized with rethinking the actions of health education individually recognizing the knowledge of the other, the world experienced by the other and from there build together a true education. Thus, making our effective work for an exclusive breastfeeding; decrease early weaning. From this understanding about the process of breastfeeding, some proposals have been drawn up in order to minimize the difficulties and increase the rate of exclusive breastfeeding. / O aleitamento materno é reconhecido como prioridade da política pública de saúde na redução da mortalidade perinatal e infantil. Entretanto apesar dos programas de incentivo ao aleitamento materno, sua implementação ocorre, no Brasil, em padrões inferiores ao preconizado. Estudo descritivo qualitativo com abordagem fenomenológica e tem por objetivo, compreender o significado do uso do aleitamento materno exclusivo na visão de mães que tiveram seus bebês internados em Unidade de Terapia Intensiva Neonatal. Os dados foram coletados no período de julho de 2011 a julho de 2012, por meio de entrevistas semi-estruturadas com mães. Utilizei da observação como forma de buscar aprofundar ou alcançar a essência das informações referentes ao fenômeno. Na análise dos discursos emergiram quatro categorias: Instinto materno e senso comum no aleitar; Aleitamento materno importante ato de amor; Motivação para continuidade ou abandono do amamentar; Influências do (des)conhecimento das informações referentes à amamentação. Resultados: o estudo revelou o sofrimento, a dor, a angústia, a frustração, sentimentos que podem ser minimizados com repensar das ações de educação em saúde de forma individualizada reconhecendo o saber do outro; o mundo vivido do outro e a partir daí construir junto um verdadeiro educar. Tornando assim nosso trabalho eficaz para um aleitamento materno exclusivo; diminuir o desmame precoce. A partir dessa compreensão quanto ao processo de aleitamento materno, algumas propostas foram elaboradas com o intuito de minimizar as dificuldades e aumentar o índice de aleitamento materno exclusivo.

Leveduras da mucosa oral, de cateter e de sangue de neonatos internados na UTIN (Unidade de Terapia Intensiva Neonatal) por período de 9 meses, foram avaliadas quanto ao perfil molecular pela técnica de PFGE. Dos 125 neonatos internados, 23 (18,4%) apresentaram leveduras na mucosa oral, sangue e cateter. Destes pacientes, obtivemos 54 amostras de leveduras, sendo 36 (66,7%) isoladas da colonização oral; 12 (22,2%) de sangue, seis (11,1%) de cateter. C. albicans foi a mais freqüente dentre as amostras isoladas da mucosa oral e sepse. C. parapsilosis foi a mais isolada dentre as amostras de cateter. Todas as amostras foram consideradas sensíveis aos antifúngicos. Estas amostras apresentaram atividade de pelo menos uma exoenzima. Dentre os 12 casos de sepse, 83,4% (10/12) foram causadas por espécies de Candida, sendo que, destas 10 candidemias, 60% (6/10) estiveram associadas com colonização oral prévia pela mesma espécie e perfil genotípico. A mortalidade devido a infecção sistêmica (septicemia) por leveduras,no período do estudo, foi de 91.6% . / Yeasts isolated from the oral mucosa, catheter and blood of neonates in na NICU (neonatal intensive care unit) over a period of 9 months, were were evaluated in regard to the molecular profile by PFGE technique. Of the 125 neonates studied, 23 (18.4%) presented yeast in their oral mucosa, blood, or catheter. From these 23 neonates, 54 samples of yeast were obtained; 36 (63.7%) from oral colonization, 12 (22.2%) from the blood, and 6 (11.1%) from the catheter. The most frequently encountered species among the samples isolated from the oral mucosa and blood was C. albicans; while C. parapsilosis was the species found most frequently among the samples obtained from catheters. All the samples were considered susceptible to antifungal agents tested. The samples presented activity of at least one exoenzyme. Among the 12 cases of sepsis, 10 (83.4%) were caused by species of Candida, and of these 10 cases, 6 (60%) were associated with previous oral colonization by the same species and genotypic profile. The mortality rate due to septicemia by yeasts was 91.6%.