金馬影展對台灣藝術電影影迷而言，就像是場神聖的盛宴，在這場儀式中，透過群體的力量，讓信念的力量益發強大。本研究嘗試依循「朝聖」（pilgrimage）的角度，將金馬影展的觀影者，視為一種信仰著藝術電影教派（cult）的信徒，他們的身份不只是閱聽人或消費者，而是一種參與者（participants）。 本研究分為三階段進行。第一階段針對金馬影展三十年來（1980～2009）的影片清單進行歷史性檔案研究，歸納出金馬影展播映影片的脈絡。第二階段對影展觀眾進行問卷調查與參與觀察，以期歸納出金馬影迷的外在觀影行為，並透過田野調查實際了解金馬影迷的參與過程。第三階段則是對影迷進行深度訪談與生命史訪談。在影展現場找尋了78位金馬影迷進行訪談，另針對3位具代表性的影迷，分別透過他們參與金馬影展的經歷，來進一步認識歷年金馬影迷參與的過程。 本研究發現金馬影展的儀式概念（The Cult of Film Festival）主要來自於三者：在時間性而言，因一年一度有如逢年過節的「週期性」而營造了儀式感；在空間性而言，因影片與影迷的「齊聚性」而營造了儀式感；除了這兩者之外，要達到類宗教的景仰標準，勢必還要有「神聖性」的概念，其神聖感則是來自於電影大師的作品，所帶來的崇拜心態。 至於影迷的朝聖歷程，本研究以三位影迷的生命史作為引述，介紹20、30、40歲各個世代的影迷，究竟是什麼樣的樣貌。而後根據大量深度訪談、田野觀察與問卷調查的結果，搭配儀式結構的模式，描繪出金馬影迷單次旅程與生涯歷程。在單次旅程的部份，可以分作「前影展時期」、「影展時期」與「後影展時期」，三者中尤以前影展時期的套票搶購與排隊劃位最具儀式性特質。在生涯歷程的部份，亦可分作「前影迷階段」、「影迷階段」與「後影迷階段」，此三者之間主要差異，是以對電影的重視、迷戀與可犧牲程度作為劃分標準。 / For art cinema fans of Taiwan, Golden Horse Film Festival just like a sacred Feast, fans gathered together every year, that increasingly the forces of faith in the ritual. This study attempts to follow the "pilgrimage" view, to imagine that Golden Horse Film Festival audience as the cult followers, their identity is not just the audience or consumers, but a participants. This study is divided into three stages. First is the archive research of Golden Horse Film Festival for the thirty years (1980~2009). Second is the festival audience questionnaire survey and participant observation, to understand the fans viewing behavior. The third stage is life history interviews. The study found that the “ritual” or “cult” concept of Golden Horse Film Festival mainly from the three points: the timing, the result of annual holidays, like the "cyclical" and created a sense of ritual; in the space, for film and fans of the "gather" of the ritual to create a sense; In addition to these two, the religious admiration to achieve the standard class is bound to also have "sacred" concept, its sacred sense is from master's work in the film, brought the worship mentality. For fans of pilgrims journey, the study quoted by three fan’s life history, describes the various generations of 20,30,40 years old. Then according to a large number of interviews, field observations and findings of the survey, with the ritual process model depicts a single journey and the career of the cinephiles. In a single part of the journey, we can divided into "pre-festival period", "Film Festival Period" and "post-festival period". Part in a career of the cinephiles can be divided into "pre-cinephile stage", "cinephile stage" and "post-cinephile stage", the main differences between the three is based on the film's importance, degree of obsession and expendable as the division of standard.

隨著女性勞動參與率的逐年提高，改變了傳統「男主外，女主內」的性別分工模式，但我國的職場並未調整為對女性-尤其是哺乳期婦女-友善的工作環境。在國際研究發現母乳的好處後，世界各地皆致力於提高哺乳率，我國也自1992年開始推廣母乳哺育計劃，但成效有限，尤其是產假結束後回到職場的哺乳率一直無法與其他國家相比。分析影響哺乳率低落的因素有母親個人因素、就業的關係、家人的支持、政策…等等，而本論文乃研究職業婦女的就業對其哺乳持續的影響。再者，我國的企業規模多屬中小企業，約有七成左右的勞工任職於中小企業，故中小企業的職場環境對女性勞工哺乳的影響更值得我們探討。 本論文之研究方法除採用文獻分析法外，尚利用深度訪談法，透過研究者自身網絡及母乳哺餵相關網站尋找合適的對象予以訪談，冀了解職業婦女在職場哺乳時的經驗及困境。而由本研究調查發現，女性員工不敢在職場光明正大的哺乳，乃因在職場進行哺乳的行為，存有佔用工作時間及影響工作績效等二種迷思；此外，職業婦女面臨幾個困境：哺乳室缺乏的空間問題、企業的競爭壓力導致哺乳時間難求、工作性質與行業別的不利差異、缺乏主管及同事的支持網絡、職場性騷擾及就業歧視情況。其中又以主管/企業主的態度，對職業婦女的持續哺乳佔最重要的影響因素。 我國職業婦女所遇到的哺乳困境，其他國家仍然存在，但不論是國際公約規範對職業婦女的哺乳保障，或是國際母乳哺餵行動聯盟(WABA)皆致力消除職場哺乳的困境，北歐國家施行的延長產後休假期間，或是美國研究的職場哺乳計劃(CLP)，其提高哺乳率成效是有目共賭，因此提供我國政府及企業借鏡，值得我們學習效法。 / In Taiwan, female labour force participates increasingly in great members. Peculiarities of this labour force have to be borne in mind. Until now, pregnancy and lactation have always been regarded as the task of woman, thus all working mothers must often choose between breastfeeding and work. There are 70% of labours working in small and medium enterprises, in which most women working. Therefore, this study focuses on small-to-medium enterprises to see how breastfeeding is regarded and treated. As we know, breastfeeding has been a national major health policy for years in Taiwan. But the breastfeeding rates after maternity leave decline quickly and the rate lagged for behind world standard. This study aims at the conflicts encountered by employed breastfeeding mothers in the workplace. A phenomenological method was conducted. A purposive sample of 12 employed breastfeeding mothers from diverse working places and from various channels were invited to participate in the study. The results of this study are as follows. People have two myths against breastfeeding in the workplace, such as occupied working time and declined working efficiency. And the main conflicts involve lack of lactation space, nursing break hard to find due to heavy work hard, the industry’s character, the rejection from manager or boss, employment discrimination and sexual harassment. The most important obstacle against working mother’s breastfeeding is the attitude of manager or boss. Reflections and policy suggestions are discussed in response to the research results.

本文研究目的是在探討跨國的投資者在面對國際投資日益開放的同時，是否充分的利用國際上的資產市場以分散投資者所面對的風險。本文參考Brandt, Cochrane, and Santa-Clara（2006），建立一種衡量國際間風險分散程度的風險分散指數，並以台灣為本國基準，取台灣前三大貿易夥伴：美國、日本、中國為外國基準，以分析此四國的國際風險分散指數，衡量的標的為各國資產市場中的主要股票交易市場指數報酬率，以分析各國風險分散的情形。此外我們亦嘗試解釋國際間風險分散的情形並解釋我們所計算出的結果，並進行一些模型參數的演算，以分析在面對其他總體變化時將會遇到的情形。經由本文的實證研究發現，對於台灣而言，在國際間的風險分散程度是偏高的，亦即，面對此四國的資產市場，台灣投資者的投資配置符合風險分散的趨勢，當匯率波動愈小時，國際風險分散程度亦將愈高，大致上與Brandt et al.(2006)之以美國為本國基準所得之國際風險分散程度結果相似。 / This thesis tries to discuss if risks are shared internationally by the international asset markets. This study refers to the Brandt, Cochrane, and Santa-Clara (2006) which built an international risk sharing index to measure the degree of international risk sharing. We set up a international risk sharing indices between Taiwan and its important trading partners, US, Japan and China by the asset returns composed by the main stock indices in each country. Furthermore, we try to explain the empirical results and to show how the degree of international risk sharing will different with the changes of the macro-variables. Our empirical analyses find that the degree of the international risk sharing for Taiwan using asset-based method is better than we think. In addition, the empirical results of this thesis are similar to Brandt et al. (2006) that if the volatility of exchange rates declines, the degree of the international risk sharing will be better.

本研究採用問卷調查法探討網路色情是否會影響青少年對強暴迷思的接受程度，以及對強暴被害人與強暴犯的態度，共訪問1,688位高中學生。 研究結果發現，網路色情的收視頻率，是預測青少年對強暴迷思的接受程度、認為強暴被害人的受傷程度和對強暴犯判刑的顯著變項，愈常收看網路色情的青少年，其接受強暴迷思的程度愈高，且愈傾向認為強暴被害人並未受到很大的傷害，並認為對強暴犯的判刑不需太重。 / This study examines the effects of Internet pornography on adolescents’ acceptance of rape myths, and their attitude towards rape victims and rapists. Data used for this study came from a survey of 1,668 high school students in Taipei, Taiwan. Results of the study show that exposure to Internet pornography were significantly related to increased acceptance of rape myths, decreased perception of rape victim sufferings, and reduced recommended prison terms to rapists.

在這高度強調「享樂」、「戀物」的年代，以西方為主導的名牌服飾，掀起了全球消費名牌風潮，眾家國際精品品牌更爭相炒熱亞洲市場，引爆「東亞」名牌消費風潮。同時除了穩固既有購買力金字塔頂端的客層，更紛紛進行品牌形象重新塑造，增添年輕、活力的元素，開發出新的潛在年輕名牌迷，更滿足了名牌迷共同追求心靈年輕年齡的慾望。在台灣，精品業者陸續在北、中、南部進駐全新精品店，加上傳播媒體大量與即時的報導時尚資訊，大大助長了名牌消費風潮。 □ 蔚為風潮的名牌消費現象，正印證了馬克思的商品「拜物」論述，在名牌服飾廣告長期和強力洗腦、品牌「崇拜偶像化」經營，使消費者容易陷入「商品崇拜」的狀態。也可印證布西亞(1993)提出的擬像概念(simulation)，精品工業便運用符號的「擬像」特質，再經由媒體的符碼轉譯，共同建構出夢幻的時尚符號。 □ 而國內迷的研究焦點，主要是媒介相關的特定內容的迷，如歌迷、影視迷、漫畫迷、電視劇迷、布袋戲迷等主題，如何迷「名牌」的相關探討付之闕如。同時，國內名牌消費相關研究焦點，在消費者部分，主要探討炫耀消費、物質主義；在精品產業部分，主要探討精品產業的行銷策略、時尚符號生產機制、精品空間塑造、仿冒品研究。本研究欲從「迷」的角度切入，把「商品拜物」、「商品崇拜」、「符號擬像」等概念再做延伸和探討，綜合心理、消費文化理論，從不同的角度描繪出名牌迷的面貌，進一步了解名牌迷、名牌與精品工業的從動關係，以及他們著迷名牌的經驗，探索名牌對於這群狂熱名牌迷的意義。

本研究以統一超商公仔代言人OPEN家族成員為觀察對象，分析其商品符號之迷群樣態，並將這樣的迷群現象與源自日本的贈品及可愛文化相連結，說明其消費意涵。 本研究的理論根據為Baudrillard的符號消費理論以及John Fiske關於迷現象的論述。研究發現，OPEN將從最初的贈品形式演變為超商集點活動的贈品主角，並進一步走上獨立品牌的道路。迷群透過不斷地消費OPEN家族這個可愛符號，達至閃躲社會規範的愉悅感以及對美好童年的懷舊想望。她們對於「可愛商品」的喜愛，其重要關鍵便是OPEN家族成員的形貌之為符號，背後所指涉的「嬰兒貌」（infancy）特質。本研究的受訪者之為迷群，展現了典型「迷」的特質，他們藉由在網路上大量貼出自己的蒐藏與OPEN家族成員的合照，作為一種文化資本的累積，為其顯著的迷群樣態。另外，這些迷群也會在網路上積極的貼文、串聯，無論是線上或線下的迷群活動均十分積極。 / The present study takes mascots of the 7-Eleven convenience stores in Taiwan　as the research objects. Through the analysis of the fans characteristics who love the symbols (i.e. the mascots), this research hopes to link the fandom to the “kawaii” and free gift cultures originated from Japan. This study adopts Baudrillard’s symbolic consumption and John Fiske’s fans theories to interpret this fandom culture prominent in Taiwan. It reveals that products of the “OPEN-jiang Family,” created by 7-Eleven convenience store, emerged originally as free gifts but gradually transform themselves to paid and even collected items as they garner more support from the zealous consumers. Through continuous consuming behaviors on these merchandises with “kawaii”characters, fans are able to escape social norms that discourage adults to act like mascot-loving children. Fans interviewed said that their love for OPEN-jiang, resulted from their consuming behaviors, help them to regain fabulous childhood memories and pleasure. The key concept behind these “kawaii” symbolic consumptions is “child-like infancy. “In addition, through the sharing of a large quantity of photos on their collections, fans treat the behavior of such capital accumulation as their main goal in fans’ life. They also actively communicate and interact with each other, both online and offline, sharing a feeling of camaraderie in the fan community.

雖然焦慮是一種普遍存在之情感性心智活動，迄今仍無充份解釋之實證資料。本研究主要是利用一種焦慮症相關的動物模式，即抬高式T形迷津，探討與焦慮症有關的神經行為機制。整部研究分兩大實驗，分別探討抬高式T形迷津的行為建構動力與破壞依核次級區域在抬高式T形迷津或其他焦慮作業上之行為表現。在實驗一檢驗抬高式T形迷津的行為內涵方面，共有四個實驗：實驗一A探討抬高式T形迷津抑制性躲避行為是否呈現消除現象；實驗一B探討破壞制約害怕神經網路對抬高式T形迷津之抑制性躲避行為的影響，並檢測自發性運動量的改變是否造成干擾效果；實驗一C探討事前暴露經驗對脫逃行為的意義；實驗一D檢測脫逃及抑制性躲避實驗程序互相干擾之可能性。實驗二探討可能涉及抬高式T形迷津或其他焦慮作業的神經機制，針對破壞依核次級區域對焦慮行為的影響進行檢測。此部分包含三個實驗，實驗二A探討依核次級區域受損對傳統焦慮動物模式抬高式十字迷津行為的影響；實驗二B採用已在實驗一建立行為效度的抬高式T形迷津，檢驗破壞依核次級區域後的迷津行為表現，並檢驗依核次級區域受損是否影響受試自發性運動量變化，以致干擾抬高式T形迷津的行為表現。另為深入探討依核的功能角色，實驗二C利用其他嫌惡作業測試破壞依核次級區域對制約躲避電擊行為的影響。實驗一結果顯示抑制性躲避行為是一包含制約害怕及探索行為等多重歷程的行為模式，而脫逃行為對情緒狀態的改變不敏感，且易受抑制性躲避作業的影響。實驗二發現破壞依核殼區同時減抑受試在抬高式十字迷津的危機評估行為、抬高式T形迷津之抑制性躲避行為及制約躲避電擊行為；而破壞依核核區的減抑效果僅見於抬高式T形迷津與制約躲避電擊作業。三個嫌惡作業的結果顯示依核核區與殼區皆涉及制約害怕歷程，但兩區的受損會表現不同焦慮行為，並在抬高式十字迷津之危機評估行為中表現出來。綜合上述二大部分實驗結果，本研究對抬高式T形迷津的行為內涵有更進一步的瞭解，並特別藉依核次級區域破壞的行為測試資料，推估中腦多巴胺系統與傳統理論所指邊緣系統在實證性解釋焦慮具同樣關鍵角色。 / Although anxiety is a well-recognized affective mental reaction, its phenomenon is not fully characterized by the empirical data. By employing a recently developed animal model named the elevated T maze (ETM), the present study investigated the neurobehavioral mechanisms of anxiety. There were two major parts of experiments designed to respectively examine the validity of this task and the involvement of limbic related areas on anxious behavior. Regarding the first part of experiments, Experiment 1A examined the effects of extinction on the inhibitory avoidance of ETM; Experiment 1B evaluated the lesions of six limbic related areas on the measures of inhibitory avoidance and escape; Experiment 1C investigated how pre-exposure experience of stress would affect the ETM behavior; Experiment 1D tested the potential affectiveness derived from different sequences of the test procedure on EMT. The second part of experiments mainly focused on comparing the lesion effects of nucleus accumbens subareas (core and shell) on behavioral measures from three anxiety-related tasks. Elevated plus maze, ETM, and active avoidance were adopted respectively in the experiments of 2A, 2B, and 2C. Results of the first part of experiments indicated 1) inhibitory avoidance of ETM containing fear conditioning and exploration components, and 2) less sensitivity to experimental manipulation for the escape of ETM. In the second part of experiments, the shell lesion significant attenuated the risk assessment behavior of elevated plus maze and inhibitory avoidance of ETM and active avoidance tasks, whereas the core lesion only produced the latter part of impairment. Both core and shell subareas are thus inferred to be involved in the conditioned avoidance, and lesions of these two areas may exert different patterns of anxious behavior. Together, the present study further characterized behavioral components of ETM. With a more systemic work in comparing lesion data of nucleus accumbens over three anxiety-related tasks, it is then suggested that the midbrain dopamine system is as crucial as the traditionally-known limbic system the traditional in terms of providing empirical explanation for the anxiety.

本研究從Leech的「禮貌原則」和Grice的「合作原則」切入討論台灣著名的反迷（anti-fan）虛擬聚集處（virtual togetherness）「吐槽版」中的異議表達。研究者初步觀察吐槽版發現，該版呈現高度言論趨同的現象、鮮見異議表達。過往反迷相關文獻指出，相對於外在強勢的主流演藝圈文化，反迷意識到自己的小眾性、弱勢性，因而可能發展出成員間緊密的小團體情誼、友善互助的人際關係。研究者欲探究，在吐槽版高度趨同的發言氛圍下，版友該如何表達異議？什麼樣的異議表達方式符合吐槽版的禮貌標準？此外，吐槽版發言高度趨同、鮮見異議、鮮見網路戰火（flaming），確為出自於版友間同仇敵愾的團結情誼、友善的人際關係嗎？ 研究發現，吐槽版版友間人際關係淡漠，完全推翻研究者對於吐槽版反迷的想像。吐槽版版友雖偏好採用溫和、委婉的方式表其異見，但若時機適當，仍會出現相對尖銳的異議；且不乏針對第一輪發言者立論的「手法」表達異議，帶有「找碴」的意味。此外，版友在表達異議時，不時出現「非護航」自清，版友不自覺會將「表達異議」等同於「護航」。「禁止護航」這版規才是約束吐槽版版友異議表達的最主要力量，而非版內的人際關係。「禁止護航」保障了版友完整情緒發洩的權利，版友在此可單方面地表達對於演藝對象的厭惡之情而不會受到他人反駁。吐槽版版友無意與他人進行「雙向溝通」，完整的、單方面的「情緒宣洩」才是他們對於吐槽版的期待。版友無意集結版眾力量共同對抗演藝圈，他們對抗的其實是「理性溝通」的概念。研究者發現，在網路社群、虛擬聚集中，人們並非只需要理性溝通，「情緒發洩」也是人們重視的發言需求。

本實驗室於先前利用莫氏水迷津試驗篩選學習快與學習慢的大白鼠，取出其海馬迴組織並進行聚合酶連鎖反應差異顯示(PCR differential display)，結果顯示學習快與學習慢的大白鼠背側海馬迴之間共有98個cDNA片段有差異表現。把這些cDNA片段進行定序並利用BLAST資料庫比對，其中一個cDNA片段為大白鼠的pias1 [protein inhibitor of activated STAT1 (signal transducer and activator of transcription 1)] 基因。為了瞭解pias1基因的表現是否和空間學習有所關聯，隨機把大白鼠分成兩組，一組為有訓練組別(有空間線索與隱藏式平台)，另一組為無訓練的組別(沒有平台，作為游泳的控制組)同時進行莫氏水迷津學習試驗。試驗完畢，取出海馬迴組織進行即時定量聚合酶連鎖反應與西方墨點法來分析PIAS1的mRNA與蛋白質的表現。結果顯示有水迷津訓練的大白鼠，其PIAS1的mRNA與蛋白質表現皆明顯的高於無訓練的組別。為了更進一步確認PIAS1在空間學習中所扮演的角色，我們利用基因轉染的技術，轉染PIAS1 siRNA至大白鼠海馬迴CA1區域抑制PIAS1的表現。我們發現轉染PIAS1 siRNA至CA1區域會抑制大白鼠在水迷津的行為表現，然而轉染野生型的PIAS1質體基因至CA1區域卻會增進水迷津試驗的學習能力，同時我們也以西方墨點法發現，當轉染PIAS1 siRNA會增加STAT1 Tyr701的磷酸化，而轉染PIAS1 WT則會抑制STAT1 Tyr701的磷酸化。為了探討PIAS1促進記憶形成的分子機制，我們發現當轉染突變型的STAT1 Y701F質體基因至CA1區域，會抑制PIAS1 siRNA所造成記憶的損害。這些實驗結果代表著PIAS1會抑制STAT1 Tyr701的磷酸化，而PIAS1促進記憶的形成可能是藉由抑制STAT1 Tyr701的磷酸化而達成。另外，我們也單獨轉染突變型的STAT1 Y701F質體基因至CA1區域，水迷津實驗結果顯示會促進空間記憶的形成。目前PIAS1在免疫的角色已有許多研究證實，但是本篇研究是第一個提出PIAS1會參與哺乳類動物學習與記憶形成探討。 / Our laboratory has previously identified 98 cDNA fragments by using PCR differential display from rat dorsal hippocampus that are differentially expressed between fast learners and slow learners from the water maze learning task. After sequencing and BLAST analysis, one of these cDNA fragments encodes the rat pias1 [protein inhibitor of activated STAT1 (signal transducer and activator of transcription 1)] gene. In order to determine whether pias1 gene expression is associated with spatial learning, naïve rats were randomly assigned to the trained group (with visual cues and platform been present) and the non-trained group (without the platform as the swimming control). The dorsal hippocampus from these animals was dissected out at the end of the training and was subjected to RNA and protein extraction for real-time PCR and Western blot analysis of PIAS1 expression, respectively. Results revealed that the pias1 mRNA level and protein level was both higher in the hippocampus of trained rats than non-trained rats. To further examine the role of PIAS1 involved in spatial learning and memory, the specific PIAS1 siRNA was used to knockdown the expression of PIAS1 in rat hippocampal CA1 region. We found that transfection of PIAS1 siRNA to the CA1 area impaired water maze performance, whereas transfection of the wild-type PIAS1 DNA plasmid to the CA1 area facilitated water maze performance in rats. Meanwhile, PIAS1 siRNA increased STAT1 phosphorylation at Tyr701 whereas PIAS1 WT decreased STAT1 phosphorylation at this residue. In the examination of molecular mechanism underlying PIAS1-mediated memory facilitation, we have found that transfection of the STAT1 Y701F mutant plasmid antagonized the memory-impairing effect of PIAS1 siRNA, whereas transfection of STAT1 Y701F alone facilitated spatial memory formation. These results together suggest that one of the molecular mechanisms underlying PIAS1-mediated memory facilitation is through decreased STAT1 phosphorylation at Tyr701. All these manipulations did not affect visible platform learning in rats. In addition to the well documented role of PIAS1 in the immune system, here we have been the first to demonstrate a novel role of PIAS1 involved in spatial memory formation in rats.

兒茶酚胺類神經傳遞系統被認為與包括記憶學習等行為功能有很重要的關連，在記憶多元化理論的假設下，該神經系統與其它者對於特定記憶學習行為應有再確認之必要。過去對於空間性記憶的研究，其相關支持證據所依據之實驗操弄泰半集中在海馬迴系統上。但仍有部份研究指出大腦中的其他區域可能同樣與一般記憶的運作有密切的關連。特別是兒茶酚胺系統所在之紋狀總體組織部位（包括尾狀核與阿控博核），vP A僅與感覺接受、運動反應及增強作用等機制有關外，同時可能也扮演影響記憶表現的重要因子。本研究使用慾求性的八角迷津為工具，藉其地點學習與反應學習這兩種不同的迷津作業，及利用兒茶酚胺類的藥物或神經毒素，探討相關的記憶習得與記憶保持歷程所造成的影響。實驗的操弄包括：(1) 迷津作業之地點學習與反應學習以探討這兩種記憶之行為機制。(2) 記憶習得與記憶保持階段以瞭解這兩種迷津作業所引發記憶之全部歷程。(3) 中樞（阿控博核或尾狀核）神經毒素之破壞以及周邊藥物注射以確認兒茶酚胺類藥物對於記憶之神經藥理機制。本研究分為兩大實驗進行，實驗一以地點學習為主，實驗二以反應學習為主。實驗結果可以簡單歸納如下：(1) 兩 種學習作業的記憶策略有不同的習得歷程及需要不同的處理訊息。(2) 在迷津學習前用神經毒素 6-OHDA 破壞尾狀核或阿控博核，皆會影響地點記憶的習得，但對於反應記憶的習得，則需要同時破壞尾狀核及阿控博核才有類似的干擾效果。(3) 相對於神經毒素 6-OHDA的干擾效果，DSP-4皆不影響地點學習與反應學習的習得歷程。(4) 在記憶保持階段中，周邊注射兒茶酚胺類藥物 d-amphetamine、haloperidol 與 propranolol均會干擾地點記憶的提取，但卻不影響反應記憶的提取表現。(5) 於地點記憶與反應記憶習得後，給予尾狀核加阿控博核的雙側 6-OHDA 注射均不影響這兩種記憶的提取表現。實驗結果顯示兒茶酚胺類神經傳導系統對於記憶功能具有明顯的影響，其中紋狀體扮演了相當重要的角色。相對於不影響記憶提取之歷程，紋狀體的破壞對記憶習得歷程有阻滯之效果，其內部之尾狀核與阿控博核分別依不同之迷津作業具有相異之效果，且多巴胺系統較正腎上腺素系統明顯的參與了影響效果，這些結果顯示兒茶酚胺類神經傳導系統與記憶表現有密切的關連。 / Catecholamine (CA) neurotransmission systems are critically involved in the control of many behavioral functions including learning and memory. The role of CA in mediating learning and memory is recently focused on the basis of multiple memory hypothesis. In addition to the previous finding of spatial memory relevant to the hippocampal areas, the striatum containing the caudate nucleus and the nucleus of accumbens is thought to be important for executing the learning and memory function. By the use of radial arm maze (RAM), the present study examined the effects of CA related neurotoxins and drugs on the acquisition and retention stages of both place and response tasks. Two major parts of experiments were designed to reveal the neurobehavioral mechanisms for the place and response tasks of RAM. Food-deprivated rats were trained to enter the arms baited with chocolate in the eight-arm maze. Specific four arms were baited for each rat in the place task, while randomly selected four arms each cued with a piece of sand paper on the arm entrance were baited for the rat in the response task.The results can be summarized as followings. (1) Differen behavioral processes were shown in performing the place and response tasks. (2) The acquisition deficits were significantly produced by 6-hydroxydopamine (6-OHDA) lesion on either caudate or accumbens for the place task, whereas the acquisition of response task was only impaired by 6-OHDA lesions of both caudate and accumbens together. (3) In contrast to 6-OHDA, adrenergic neurotoxin DSP-4 did not significantly affect subjects to acquire either task. (4) During the retention stage, the performance of place task was significantly disrupted by d-amphetamine, haloperidol, or propranolol. However, this was not the case for the retrieval of response task. (5) Once acquired, neither place nor response task performamce could be influenced by 6-OHDA simultaneously administered on the caudate and accumbens areas.Taken together, these data collected from RAM support the idea that the striatal CA is essential for the leraning and memory. Shift of the CA neurotransmission function induced by either 6-OHDA lesions or relevant drugs can disrupt the RAM behavior, which impairment to be detectable is depended on the learning task itself as well as the time of a specific task being leraned.