Dieses Dissertationsprojekt befasst sich mit der Bedeutung von urbaner Infrastruktur für syrische Stadtbewohner:innen vor Beginn des Krieges, der auf die friedlichen Proteste im Jahre 2011 folgte. Fokus der Arbeit liegt auf den Infrastrukturnetzwerken Wasserversorgung und Müllentsorgung in der Stadt Aleppo im Nordwesten Syriens. In den Interviews, die für die Forschungsarbeit mit aleppinischen Exilant:innen geführt wurden, zeigte sich, dass die beiden Netzwerke auch über ihren Zusammenbruch im Kontext kriegerischer Auseinandersetzungen in Aleppo (insbesondere zwischen 2012 und 2016) hinaus Funktionen im Leben der Befragten erfüllten – nun mehr weit weg von Aleppo im westeuropäischen Exil. Beispielsweise diente die Beschreibung von privaten Praktiken und institutionalisierten Abläufen der Müllentsorgung auch im Exil der Einteilung der aleppinischen Bevölkerung in bestimmte soziale Gruppen. Auch die politische Bedeutung der Wasserversorgung überdauerte den infrastrukturellen Kollaps. Vor diesem Hintergrund diskutiert diese Dissertation mit Hinblick auf insbesondere Literatur inspiriert durch die actor-network theory die zeitliche Verortung und Entstehung von Infrastrukturen. Insbesondere wird hinterfragt, ob die sozialen und materiellen Komponenten, die gemeinsam ein Infrastrukturnetzwerk bilden, notwendigerweise in Raum und Zeit koexistieren müssen. Hier schlägt die Arbeit ein Konzept von Infrastruktur vor, die zu verschiedenen Zeitpunkten (dispersed in time) und, im Migrationskontext, auch an verschiedenen Orten entsteht. / This dissertation project focuses on the meaning of urban infrastructure for Syrian city dwellers before the beginning of the war that followed the peaceful protests in 2011. The project thereby focuses on the infrastructural networks of water supply and waste disposal in the city of Aleppo in northwestern Syria. Interviews conducted with Aleppans in exile showed how the two networks continued to play role in the interlocutors’ lives in Western Europe also beyond the infrastructural breakdown in the context of armed conflict in Aleppo (especially between 2012 and 2016). For example, the description of private practices and institutionalized processes of garbage disposal still served to divide the Aleppan population into specific social groups in exile. Likewise, the political meaning of water supply in Aleppo survived the infrastructural collapse of the provision of water in the city. Against this background, this dissertation discusses the temporality of the emergence of infrastructures with regard to literature inspired by actor-network theory. In particular, it questions whether the social and material components that in their interactions form an infrastructural network necessarily need to coexist in time and space. Here, the work proposes a concept of infrastructure that emerges at different points in time (infrastructure as dispersed in time), and, in the context of migration, also in different places.

The hypothesis of this study entails the formulation of interpretative solutions for J. S. Bach's Capriccio in B flat major. The "Interpretative Analysis" mentioned in the title, strives to provide a synthesis in which the cognitive understanding of the music can contribute to a more informed aesthetic interpretation of the music. In the ensuing study this objective is realised by examining the origin of the work and the sources from which it was handed down, the style in which the Capriccio was composed and conceived, the performance practices prevalent in the early eighteenth century and the applicability thereof to the music of J. S. Bach, the structure of the Capriccio, and lastly the different instruments on which the Capriccio can be performed and the impact which this choice has on any performance thereof. / Department of Musicology / M.Mus.

This thesis explores the commercial links between Scotland and France in the long seventeenth century, with a focus on the Scottish mercantile presence in France’s Atlantic ports, particularly during periods of domestic and international upheaval. This study questions long-held assumptions regarding this relationship, asserting that the ‘Auld Alliance’ continued throughout the period, despite the widely held belief that it ended in 1560. Such assumptions have led scholars largely to ignore the continuing commercial relationship between Scotland and France in the long seventeenth century, focusing instead on the ‘golden age’ of the Auld Alliance or the British relationship with France in the eighteenth century. Such assumptions have been fostered by the methodological approaches used in the study of economic history to date. While I acknowledge the relevance of traditional quantitative approaches to economic history, such as those pioneered by T. C. Smout and which continue to be followed by historians such as Philipp Rössner, I follow alternative methods that have been recently employed by scholars such as Henriette de Bruyn Kops, Sheryllynne Haggerty, Xavier Lamikiz, Allan Macinnes and Steve Murdoch. These scholars have pioneered methodologies that prioritise private sources, allowing us to delve into the motivations and actions of the individuals who actually effected trade, be they merchants, factors, skippers or manufacturers. The core of my research has therefore entailed the discovery and use of previously untapped archival material including account books, letter books and correspondence, which illuminate the participation of these individuals in international trade. Such a study, while filling a specific gap in our understanding of Scotland’s overseas relations, applies a more social methodology to this topic, suggesting that scholars’ approaches need to be fundamentally altered if we are truly to understand the whole picture of Scotland’s, or indeed any nation’s, commercial relationships or wider economic position.

In this dissertation, I examine antagonistic relationships between women writers in the first half of the eighteenth century, focusing on the works of Delarivier Manley, Martha Fowke Sansom, Eliza Haywood, and Laetitia Pilkington. Professional rivalry among women writers represents an under-studied but vital element of the history of print culture in the early eighteenth century. I argue that the shared burden of negotiating the complicated literary marketplace did not, as critics have at times suggested, inspire women who wrote for print publication to feel for one another a sisterly benevolence. Rather, fine gradations in social class, questions of genre status and individual talent, and -- perhaps most importantly -- clashing literary ambitions spurred early eighteenth-century women writers into vicious rivalries recorded in print and driven by print culture. Women documented their literary battles in poems, in prefaces, and in autobiographical texts replete with self-justification and with attacks on former friends or disappointing patronesses. This dissertation recognizes rivalry as a crucial mode of interaction between eighteenth-century literary women and analyzes the ways in which these professional women writers labored to defend themselves not just against patriarchal pressures but against one another. In doing so, it contributes to the construction of a more complete literary history of the first half of the eighteenth century by exploring how early eighteenth-century women writers imagined their own professional lives, how they imagined the professional lives of other women, and how they therefore believed themselves influenced (or claimed themselves influenced) by the support or detraction of other women. The first two chapters of this dissertation focus on Delarivier Manley's career and writings, while the second two address the entangled writing lives of Eliza Haywood and Martha Fowke Sansom. The concluding chapter briefly examines Laetitia Pilkington's Memoirs. I investigate the way these women employed the practice of life-writing as a means of self-construction, self-promotion, and public appeal. / text

During the 1740’s, Hudson Bay went from an obscure backwater of the British Empire to a locus of colonial ambition. Arthur Dobbs revitalized Northwest Passage exploration, generating new information about the region’s environment and indigenous peoples. This study explores evolving English and British representations of Hudson Bay’s climate and landscape in travel and natural history writing, and probes British anxieties about foreign environments. I demonstrate how Dobbs’ ideology of improvement optimistically re-imagined the North, opening a new discursive space wherein the Subarctic could be favourably described and colonized. I examine how Hudson Bay explorers’ responses to difficulties in the Arctic and Subarctic were seen to embody, even amplify, central principles and features of eighteenth-century British culture and identity. Finally, I investigate how latitude served as a benchmark for civilization and savagery, subjugating the Lowland Cree and Inuit to British visions of settlement and improvement in their home territories.

Thesis (MPhil)--University of Stellenbosch, 2007. / ENGLISH ABSTRACT: This thesis will focus on Barnard’s representations of gender and landscape during her tour into the interior of the South of Africa. Barnard’s conscious representation of herself as a woman with many different social roles gives the reader insight into the developing gender roles at the time of an emerging feminism. On their tour, Barnard reports on four aspects of the interior, namely the state of cultivation of the land, the type of food and accommodation available in the interior, the possibilities for hunting and whether the colony will be a valuable acquisition for Britain. Barnard’s view of the landscape is representative of the eighteenth century’s preoccupation with control over and classification of nature. She values order and cleanliness in her vision of a domesticated landscape. She appropriates the land in wanting to make it useful and beautiful to the colonisers. However, her representations of the landscape, as well as its inhabitants, remain ambivalent in terms of the discourse of imperialism because she is unable to adopt an unequivocal colonial voice. Her complex interaction with the world of colonialism is illustrated by, on the one hand, her adherence to the desire to classify the inhabitants of the colony according to the eighteenth century’s fascination with classification and, on the other hand, her recognition of the humanity of the individuals with whom she interacts in a move away from the colonial stance. / AFRIKAANSE OPSOMMING: Hierdie tesis fokus op Barnard se voorstellings van gender en landskap gedurende haar toer in die binneland van die suide van Afrika. Barnard se bewuste voorstelling van haarself as ‘n vrou met vele sosiale rolle gee die leser insig in die ontwikkelende genderrolle gedurende ‘n tydperk van ontluikende feminisme. Gedurende haar toer doen Barnard verslag oor vier aspekte van die binneland, naamlik hoeveel van die grond reeds bewerk is, die tipe kos en akkommodasie wat beskikbaar is, die jagmoontlikhede, en of die kolonie ‘n waardevolle aanwins vir Brittanje sal wees. Barnard se beskouing van die landskap is verteenwoordigend van die agtiende-eeuse obsessie met beheer oor en klassifikasie van die natuur. Sy heg groot waarde aan orde en netheid in haar visie van ‘n getemde landskap. Sy lê beslag op die land deurdat sy dit bruikbaar en mooi wil maak vir die kolonialiste. Haar voorstellings van die landskap sowel as die inwoners weerspieël egter haar ambivalente posisie jeens die koloniale diskoers omdat sy sukkel om ‘n ondubbelsinnige koloniale stem te gebruik. Haar komplekse interaksie met die wêreld van kolonialisme word weerspieël deur, enersyds, haar navolging van die koloniale neiging om die inwoners van die land te kategoriseer in lyn met die agtiende-eeuse obsessie met klassifikasie en, andersyds, haar herkenning van die menslikheid van die individue met wie sy kontak maak in ‘n skuif weg van die koloniale standpunt.

The hypothesis of this study entails the formulation of interpretative solutions for J. S. Bach's Capriccio in B flat major. The "Interpretative Analysis" mentioned in the title, strives to provide a synthesis in which the cognitive understanding of the music can contribute to a more informed aesthetic interpretation of the music. In the ensuing study this objective is realised by examining the origin of the work and the sources from which it was handed down, the style in which the Capriccio was composed and conceived, the performance practices prevalent in the early eighteenth century and the applicability thereof to the music of J. S. Bach, the structure of the Capriccio, and lastly the different instruments on which the Capriccio can be performed and the impact which this choice has on any performance thereof. / Department of Musicology / M.Mus.

DNA-Methylierung spielt eine wichtige Rolle bei der Kontrolle der Chromatinorganisation und Genregulation in höheren Eukaryoten und muss zusammen mit der genetischen Information in jedem Zellzyklus dupliziert werden. Bei Mammalia wird DNA durch die DNA-Methyltransferase 1 (DNMT1) methyliert, die dabei mit nuklearen Replikationsstellen (RF) assoziiert und so die Erhaltung des Methylierungsmusters mit der Duplikation der DNA verbindet. In dieser Arbeit wurden die Funktion der regulatorischen Sequenzen in der N-terminalen Domäne von DNMT1 bei der Kontrolle ihrer subnuklearen Lokalisierung während des Zellzyklus und die evolutionäre Konservierung dieser Sequenzen, sowie die Mechanismen die eine Assoziation von Proteinen mit RF vermitteln, untersucht. Es konnte gezeigt werden, dass DNMT1 eine dynamische Verteilung im Kern aufweist, die durch regulatorische Sequenzen zellzyklusabhängig gesteuert wird. Um die subnukleare Verteilung von DNMT1 während des Zellzyklus zu untersuchen, wurden RFP-Ligase Fusionsproteine hergestellt, die als Marker für die Identifikation von Zellzyklusstadien in lebenden Zellen dienen. Verschiedene, mit GFP fusionierte DNMT1 Mutanten wurden zusammen mit RFP-Ligase exprimiert und über einen ganzen Zellzyklus hinweg mit 4-dimensionaler Lebendzellmikroskopie verfolgt. Die PBD (PCNA-Bindungsdomäne) bewirkt die Lokalisierung von DNMT1 an RF während der S-Phase, und die TS (targeting sequence) vermittelt die Retention von DNMT1 an spät replizierendem Heterochromatin von der späten S- bis zur frühen G1-Phase. Im Gegensatz dazu scheint die PBHD (Polybromohomologiedomäne) für die Freisetzung von DNMT1 von perizentrischen Regionen während der G1-Phase notwendig zu sein. Eine Überexpression der TS zu Störung dieser Assoziation, senkt die Überlebensrate der Zellen und fördert die Bildung von Mikronuklei sowie die Verschmelzung von zentromerem Heterochromatin. Diese Ergebnisse zeigen eine neue Funktion für die TS bei der Assoziation von DNMT1 mit perizentrischem Heterochromatin von der später S- über die G2-Phase bis hin zur Mitose, die eine wichtige Voraussetzung für die Erhaltung der DNA-Methylierung und Heterochromatinstruktur und -funktion ist. Datenbankanalysen zeigten, dass es sich bei der TS um eine einzigartige Domäne innerhalb der DNMT1 Proteinfamilie handelt. Innerhalb der DNMT1 Familie besitzen nur die DNMT1 Proteine der Metazoen die PBD. Das lässt vermuten, dass die Verknüpfung von Beibehaltung der DNA Methylierung mit der DNA Replikation nur in Metazoen auftritt, während in Pflanzen und Pilzen alternative Mechanismen zur Aufrechterhaltung des Methylierungsmusters, wahrscheinlich vermittelt durch die TS, zur Anwendung kommen. Die evolutionäre Konservierung von Mechanismen, zur Assoziation von Proteine mit RF in Säugerzellen, wurde durch die Analyse der Säugerproteine PCNA, DNA Ligase I und DNMT1 in Drosophila-zellen direkt getestet. Von allen untersuchten Proteinen assoziiert nur PCNA mit RF, während die anderen nur eine diffuse Verteilung innerhalb des Kerns zeigten, obwohl sie eine funktionale PBD enthalten. Überraschenderweise assoziierte auch die Drosophila DNA Ligase I in Säugerzellen nicht aber in Drosophila-zellen mit RF. Diese Ergebnisse weisen auf Unterschiede in der Dynamik und dem Aufbau der Replikationsmaschinerie in diesen entfernt verwandten Organismen hin, was mit der Vergrösserung und höheren Komplexität des Säugergenoms korreliert. / DNA methylation constitutes an essential epigenetic mark controlling chromatin organization and gene regulation in higher eucaryotes, which has to be duplicated together with the genetic information at every cell division cycle. In mammals duplication of DNA methylation is mediated by DNA methyltransferase-1 (DNMT1). It associates with sites of nuclear DNA replication, called replication foci (RF), and thereby couples maintenance of DNA methylation to DNA duplication. In this work, we have analyzed the role of regulatory sequences in the N-terminal domain of DNMT1 in controlling its subnuclear localization throughout the cell cycle, and the evolutionary conservation of these sequences and of the mechanisms that mediate association of proteins with RF. We provide evidence that DNMT1 shows dynamic subnuclear distribution that is controlled by the regulatory sequences depending on the cell cycle stage. To determine the subnuclear distribution of DNMT1 throughout the cell cycle, an RFP-Ligase fusion protein was developed as a marker that allows identification of the cell cycle stage in live cells. Various DNMT1 mutants fused to GFP were coexpressed with RFP-Ligase and imaged by 4-dimensional live cell microscopy during an entire cell cycle. The PBD (PCNA binding domain) drives the localization of DNMT1 at RF throughout S phase and the TS (targeting sequence) mediates retention of DNMT1 only at the late replicating pericentric heterochromatin from late-S phase until early-G1. In contrast, the PBHD (polybromo homology domain) seems to be required for unloading DNMT1 from the pericentric regions in G1. Overexpression of the TS to interfere with this association lowers cell viability and induces the formation of micronuclei and coalescence of centromeric heterochromatin. These results bring forth a novel function of the TS in mediating association of DNMT1 with pericentric heterochromatin from late-S phase through G2 until mitosis, which is important for maintenance of DNA methylation, and heterochromatin structure and function. Database searches indicate that the TS is a domain unique to the DNMT1 family of proteins. Amongst the DNMT1 family, only the metazoan DNMT1 proteins have the PBD. This suggests that coupling of maintenance of DNA methylation with DNA replication occurs only in metazoans, while plants and fungi have alternative mechanisms that maintain DNA methylation patterns, probably mediated by the TS. The evolutionary conservation of the mechanisms by which proteins associate with RF in mammalian cells was directly tested by analyzing the ability of mammalian replication proteins PCNA and DNA Ligase I as well as DNMT1 to associate with RF in Drosophila cells. Of all the proteins tested, only PCNA associated with RF while the others showed diffused nuclear distribution although they contain a functional PBD. Surprisingly, Drosophila DNA Ligase I associates with RF in mammalian but not in Drosophila cells. These results suggest differences in the dynamics and organization of the replication machinery in these distantly related organisms, which correlates with the increased size and complexity of mammalian genomes.

Continuing the discussion of interpreting J. S. Bach's lute music on the guitar, this dissertation seeks to demonstrate that Schenkerian analysis can assist the modern classical guitarist to better understand Bach's music. In particular, the Schenkerian approach provides an important methodology for studying Bach's music in depth, and then guiding performance practice on the guitar. Although there are many books and articles about transcribing, interpreting and performing Bach's music on the guitar, they do not apply Schenkerian analysis to guitar performance. This research will fill in the lacuna in this field, while promoting music scholarship and enhancing the performance practice of classical guitarists.

The main purpose of this dissertation is to offer classical guitarists an additional analytical technique for interpreting and performing the music of Johann Sebastian Bach. While this mode of analysis can be successfully applied to any of the instrumental works by Bach frequently transcribed and performed by guitarists, I have chosen for this study my recent transcription of the Partita in A minor for solo flute traverso, BWV 1013. With a continuo-based, harmonic realization of the Partita, I contribute to the existing guitar repertoire by offering a new transcription of this work, while demonstrating how historical concepts of rhetorical structure and aesthetics found in relevant primary source material can inspire a new approach to analysis, transcription, and performance practice. In this way, my investigations create additional perspectives for classical guitarists regarding the analysis and performance of this work, while complementing traditional harmonic analysis and subject labeling. Although it is my hope that this new transcription of the Partita will serve as an important contribution to the existing literature, the main purpose of this dissertation resides in the musico-rhetorical analytical technique and its implications on performance practice for classical guitarists.