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Ochrana soukromí na Internetu / Internet privacy protectionMalina, Lukáš January 2010 (has links)
Anonymous authentication is a mean of authorizing a user without leakage of user personal information. The technology of Anonymous Authentication Systems (AAS) provides privacy of the user and yet preserves the security of the system. This thesis presents the basic cryptographic primitives, which can provide anonymous authentication. Among these primitives there are usually some asymmetric cryptosystems, but an essential part of anonymous authentication is based on zero knowledge protocols, blind signature schemes, threshold group schemes, etc., that are presented in Chapter 1. Generally, Anonymous Authentication Systems have application as electronic coin, electronic cash, group signatures, anonymous access systems, electronic vote, etc., which are analyzed and presented in Chapters 2 and 3. In the practical section, the implementation (in the environment .NET in C#) of the AAS system is presented and described in Chapter 4, which is being developed at the FEEC BUT.
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Analyzing and Enhancing Routing Protocols for Friend-to-Friend OverlaysRoos, Stefanie 09 August 2016 (has links) (PDF)
The threat of surveillance by governmental and industrial parties is more eminent than ever. As communication moves into the digital domain, the advances in automatic assessment and interpretation of enormous amounts of data enable tracking of millions of people, recording and monitoring their private life with an unprecedented accurateness. The knowledge of such an all-encompassing loss of privacy affects the behavior of individuals, inducing various degrees of (self-)censorship and anxiety. Furthermore, the monopoly of a few large-scale organizations on digital communication enables global censorship and manipulation of public opinion. Thus, the current situation undermines the freedom of speech to a detrimental degree and threatens the foundations of modern society.
Anonymous and censorship-resistant communication systems are hence of utmost importance to circumvent constant surveillance. However, existing systems are highly vulnerable to infiltration and sabotage. In particular, Sybil attacks, i.e., powerful parties inserting a large number of fake identities into the system, enable malicious parties to observe and possibly manipulate a large fraction of the communication within the system. Friend-to-friend (F2F) overlays, which restrict direct communication to parties sharing a real-world trust relationship, are a promising countermeasure to Sybil attacks, since the requirement of establishing real-world trust increases the cost of infiltration drastically. Yet, existing
F2F overlays suffer from a low performance, are vulnerable to denial-of-service attacks, or fail to provide anonymity.
Our first contribution in this thesis is concerned with an in-depth analysis of the concepts underlying the design of state-of-the-art F2F overlays. In the course of this analysis, we first extend the existing evaluation methods considerably, hence providing tools for both our and future research in the area of F2F overlays and distributed systems in general. Based on the novel methodology, we prove that existing approaches are inherently unable to offer acceptable delays without either requiring exhaustive maintenance costs or enabling denial-of-service attacks and de-anonymization.
Consequentially, our second contribution lies in the design and evaluation of a novel concept for F2F overlays based on insights of the prior in-depth analysis. Our previous analysis has revealed that greedy embeddings allow highly efficient communication in arbitrary connectivity-restricted overlays by addressing participants through coordinates and adapting these coordinates to the overlay structure. However, greedy embeddings in their original form reveal the identity of the communicating parties and fail to provide the necessary resilience in the presence of dynamic and possibly malicious users. Therefore, we present a privacy-preserving communication protocol for greedy embeddings based on anonymous return addresses rather than identifying node coordinates. Furthermore, we enhance the communication’s robustness and attack-resistance by using multiple parallel embeddings and alternative algorithms for message delivery. We show that our approach achieves a low communication complexity.
By replacing the coordinates with anonymous addresses, we furthermore provably achieve anonymity in the form of plausible deniability against an internal local adversary. Complementary, our simulation study on real-world data indicates that our approach is highly efficient and effectively mitigates the impact of failures as well as powerful denial-of-service attacks. Our fundamental results open new possibilities for anonymous and censorship-resistant applications. / Die Bedrohung der Überwachung durch staatliche oder kommerzielle Stellen ist ein drängendes Problem der modernen Gesellschaft. Heutzutage findet Kommunikation vermehrt über digitale Kanäle statt. Die so verfügbaren Daten über das Kommunikationsverhalten eines Großteils der Bevölkerung in Kombination mit den Möglichkeiten im Bereich der automatisierten Verarbeitung solcher Daten erlauben das großflächige Tracking von Millionen an Personen, deren Privatleben mit noch nie da gewesener Genauigkeit aufgezeichnet und beobachtet werden kann. Das Wissen über diese allumfassende Überwachung verändert das individuelle Verhalten und führt so zu (Selbst-)zensur sowie Ängsten. Des weiteren ermöglicht die Monopolstellung einiger weniger Internetkonzernen globale Zensur und Manipulation der öffentlichen Meinung. Deshalb stellt die momentane Situation eine drastische Einschränkung der Meinungsfreiheit dar und bedroht die Grundfesten der modernen Gesellschaft.
Systeme zur anonymen und zensurresistenten Kommunikation sind daher von ungemeiner Wichtigkeit. Jedoch sind die momentanen System anfällig gegen Sabotage. Insbesondere ermöglichen es Sybil-Angriffe, bei denen ein Angreifer eine große Anzahl an gefälschten Teilnehmern in ein System einschleust und so einen großen Teil der Kommunikation kontrolliert, Kommunikation innerhalb eines solchen Systems zu beobachten und zu manipulieren. F2F Overlays dagegen erlauben nur direkte Kommunikation zwischen Teilnehmern, die eine Vertrauensbeziehung in der realen Welt teilen. Dadurch erschweren F2F Overlays das Eindringen von Angreifern in das System entscheidend und verringern so den Einfluss von Sybil-Angriffen. Allerdings leiden die existierenden F2F Overlays an geringer Leistungsfähigkeit, Anfälligkeit gegen Denial-of-Service Angriffe oder fehlender Anonymität.
Der erste Beitrag dieser Arbeit liegt daher in der fokussierten Analyse der Konzepte, die in den momentanen F2F Overlays zum Einsatz kommen. Im Zuge dieser Arbeit erweitern wir zunächst die existierenden Evaluationsmethoden entscheidend und erarbeiten so Methoden, die Grundlagen für unsere sowie zukünftige Forschung in diesem Bereich bilden. Basierend auf diesen neuen Evaluationsmethoden zeigen wir, dass die existierenden Ansätze grundlegend nicht fähig sind, akzeptable Antwortzeiten bereitzustellen ohne im Zuge dessen enorme Instandhaltungskosten oder Anfälligkeiten gegen Angriffe in Kauf zu nehmen.
Folglich besteht unser zweiter Beitrag in der Entwicklung und Evaluierung eines neuen Konzeptes für F2F Overlays, basierenden auf den Erkenntnissen der vorangehenden Analyse. Insbesondere ergab sich in der vorangehenden Evaluation, dass Greedy Embeddings hoch-effiziente Kommunikation erlauben indem sie Teilnehmer durch Koordinaten adressieren und diese an die Struktur des Overlays anpassen. Jedoch sind Greedy Embeddings in ihrer ursprünglichen Form nicht auf anonyme Kommunikation mit einer dynamischen Teilnehmermengen und potentiellen Angreifern ausgelegt. Daher präsentieren wir ein Privätssphäre-schützenden Kommunikationsprotokoll für F2F Overlays, in dem die identifizierenden Koordinaten durch anonyme Adressen ersetzt werden.
Des weiteren erhöhen wir die Resistenz der Kommunikation durch den Einsatz mehrerer Embeddings und alternativer Algorithmen zum Finden von Routen. Wir beweisen, dass unser Ansatz eine geringe Kommunikationskomplexität im Bezug auf die eigentliche Kommunikation sowie die Instandhaltung des Embeddings aufweist. Ferner zeigt unsere Simulationstudie, dass der Ansatz effiziente Kommunikation mit kurzen Antwortszeiten und geringer Instandhaltungskosten erreicht sowie den Einfluss von Ausfälle und Angriffe erfolgreich abschwächt. Unsere grundlegenden Ergebnisse eröffnen neue Möglichkeiten in der Entwicklung anonymer und zensurresistenter Anwendungen.
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Contribution au renforcement de la protection de la vie privée. : Application à l' édition collaborative et anonyme des documents.Vallet, Laurent 18 September 2012 (has links)
Ce travail de thèse a pour objectif de renforcer la protection de la vie privée dans l'édition collaborative de documents dématérialisés. Une première partie de notre travail a consisté en l'élaboration d'un modèle sécurisé d'éditeur collaboratif de documents. La confidentialité des documents est assurée grâce à un contrôle d'accès décentralisé. Une seconde partie a été de protéger l'identité des utilisateurs communicants en assurant leur anonymat lors de l'édition des documents. Notre concept d'éditeur collaboratif est fondé sur l'utilisation d'ensembles de modifications apportées à un document, que nous nommons deltas, lesquels définissent des versions du document. Les deltas permettent de conserver l'historique des modifications successives. Lorsqu'une nouvelle version d'un document apparait, seul le nouveau delta qui en découle doit être transmis et stocké : les documents sont ainsi distribués à travers un ensemble de sites de stockage. Cela permet, d'une part, d'alléger la charge du gestionnaire des versions des documents, et d'autre part, d'améliorer la sécurité générale. La récupération décentralisée d'une nouvelle version nécessite seulement celle des deltas manquants par rapport à une version précédente; elle est donc moins coûteuse que la récupération du document en entier. L'information du lien entre les deltas est enregistrée directement avec les deltas et non dans une table ou dans un objet de métadonnées ce qui améliore leur sécurité. La gestion des versions est faite afin de maintenir une cohérence entre les versions. / This thesis aims to strengthen the protection of privacy of authors in collaborative editing of electronic documents. The first part of our work consisted in the design a secured model for a collaborative document editor. Documents' confidentiality is ensured through a decentralized access control mechanism. A second part of the work was to protect the identity of communicating users by ensuring their anonymity during collaborative document editing. Our concept of collaborative editor is based on the use of sets of modifications for a document, which we call textit{deltas}. Thus, deltas define versions of the document and they can keep the history of subsequent modifications. When a new version of a document appears, only the new delta that results must be transmitted and stored : documents are thus distributed across a set of storage sites (servers). We show how this allows, first, to reduce the load of document version control system, and secondly, to improve overall security of the collaborative system. Decentralized recovery of a new version requires only recovery of appropriate deltas against a previous version and is therefore more efficient than recovering the entire document. The information of the link between deltas is stored directly with deltas and not in a table or a metadata object, that improves their security. The version control system maintains consistency between versions. Once a user has retrieved versions, she holds them in local, and the history can be accessed at any time without being necessary to connect to the central server. Deltas can be identified, indexed and maintained their integrity through the use of hash functions.
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Schulman och Glöm mig - mellan fiktion och autenticitet : En litteraturvetenskaplig läsning av alkoholismens roll i Glöm mig med fokus på självframställning, tematik och samband mellan fiktion och verklighet / Schulman and Glöm mig - between fiction and authenticity : A literature scientific comparison reading of alcoholism in Glöm mig with focus on the self description and the relation between fiction and realityKhan, Nadim January 2019 (has links)
This essay has a focus on self description and alcoholism as a literary function in Alex Schulman’s Glöm mig. Similarities between the book Alcoholics Anonymous (Stora Boken) and the twelve step programme (Tolvstegsprogrammet) is based on how the narrative could be characterized by the authenticity of the disease portrayal. The connection between the narrative and Alcoholics Anonymous is compared with how the main characters are portrayed and how alcoholism functions in the book. The study reveals that the story could most likely be percieved as an accurate portrayal of alcoholism as a disease, due to certain cirumstances. The connection between the testimonies of alcoholism as a disease in Alcoholics Anonymous and the narrative is an important parallel as it can strengthen the story’s credibility. It’s possible to interpret the story as a testimony from someone in close relationship to an alcoholic. An authentic story like this occurs frequently in Swedish contemporary literature and could be one of the reasons behind the novel’s commercial breakthrough. The privileged position of the author should be considered as a contributing factor leading to the positive public reactions when the novel was published. It should also be considered as having an impact on the reader’s perception of the autobiographic novel’s credibility. It’s probable that, due to these circumstances, the line between a true story and a fictional one, could be dissolved for the reader. In connection with the circumstances with Schulman’s authorship, a number of factors that may impact the reading of the book, have been presented. These are explained in comparison to other authors with similar backgrounds, who have been publishing books about similiar topics.
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The users’ activities on Yiguan : An Audience Analysis on An Anonymous Social MediaSun, Yiman January 2019 (has links)
Yiguan is a new-emerging mobile application which is popular in China. Different from the traditional social media, Yiguan enables users to have interaction and communications anonymously online. Compared to other anonymous social media, Yiguan is nether proximity-based nor tie-based. The identity of Yiguan users can be completely anonymous. Users will not have a personal profile and home pages on Yiguan. Anonymity makes it possible that users wear masks when they present themselves and interact with others. It is possible for them to get rid of the constraint, escaping from repetitive everyday life. This thesis based on the empirical qualitative research, conduct an audience analysis on Yiguan’s users. I’d like to explore what users do on Yiguan and how they utilize the space of Yiguan. This thesis wishes to identify the activities of users on Yiguan, and explore the characteristics of user’s activities. Combing the critical theories from Mead, Goffman, and Walther, this thesis will provide a vivid sketch of users on Yiguan.
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Princípio do melhor interesse da criança: construção teórica e aplicação prática no direito brasileiro / The principle of the best interest of the child: theoretical construction and practical usage in Brazilian law.Colucci, Camila Fernanda Pinsinato 21 May 2014 (has links)
Esta pesquisa objetivou estudar o princípio do melhor interesse da criança tanto em seu viés teórico quanto prático, na tentativa de se concluir se é possível ou não adotar-se critérios predeterminados para serem seguidos na tomada de decisões em questões envolvendo crianças e adolescentes. Na primeira parte, teórica, estudou-se o conteúdo do melhor interesse, e se poderia ele ser entendido como regra de interpretação, direito fundamental ou princípio. Já a segunda parte, prática, buscou analisar como os tribunais vêm decidindo algumas questões que resvalam no melhor interesse. Para tal, alguns institutos foram selecionados (guarda, adoção, parto anônimo, visitas e educação). A análise da guarda passou pela sua diferenciação entre colocação em família substituta e atribuição a um dos pais em caso de separação. Discutiu-se a possibilidade de atribuição a terceira pessoa e de imposição da modalidade compartilhada. Estudou-se o direito de visitas para o caso de a guarda ter sido atribuída a somente um dos pais. Estendeu-se a pesquisa para a hipótese de garantir-se esse direito a amigos, padrastos, madrastas e padrinhos. A adoção foi estudada nas modalidades à brasileira, intuitu personae e internacional. Ainda, analisou-se a possibilidade de adoção por casal homoafetivo. Embora inexistente no direito brasileiro, o parto anônimo foi analisado para se observar se viável e necessário em nosso ordenamento. Por fim, estudou-se o direito à educação, realçando-se alguns aspectos como a possibilidade de o ensino ser realizado fora de estabelecimentos oficiais, transporte de crianças até suas escolas e a possibilidade de exigirem-se vagas em creches. / This research aimed to study the principle of the best interest of the child, both in theory and in practice, in an attempt to conclude whether it is possible or not to adopt predetermined criteria to be followed in making decisions on issues involving children and adolescents. In the first part, theoretical, the content of the best interest was studied, as well as the possibility of understanding it as a rule of interpretation, fundamental right or principle. The second part, practical, sought to analyze how the courts have been deciding issues involving the best interest. In doing so, some institutes were selected (guardianship, adoption, anonymous childbirth, visits and education). The analysis of the guardianship passed by differentiating between placement in foster family and its assignment to one of the parents in case of separation. The possibility of assigning it to a third person and the imposition of shared custody were discussed. The visitation rights in case when the custody has been awarded to only one parent was studied. The research was extended to the hypothesis of granting this right to friends, stepfathers, stepmothers and godfathers or godmothers. The research studied Brazilian, intuitu personae and international adoptions, as well as the possibility of adoption by homosexual couples. Although non-existing under Brazilian law, the anonymous childbirth was analyzed to observe if it is viable and needed in our system. Finally, the right of education was studied, and aspects such as the possibility of homeschooling, transportation of children to their schools and the requiring of vacancies in childcare facilities were highlighted.
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A delicadeza dos meus sentimentos: a dependência alcoólica feminina representada por homens e mulheres em processo de recuperação alcoólica / The tenderness of my feelings: female alcohol dependence as represented by men and women in alcohol rehabilitationLuccas, Vívian Nara Bracco 09 November 2015 (has links)
RESUMO: Estudos epidemiológicos têm demonstrado o aumento de consumo alcoólico e da dependência alcoólica entre mulheres, algo que era até então considerado majoritariamente um problema da população masculina. A presente investigação parte desta constatação, mas também, a problematiza, à medida que se observa que o processo de emancipação feminina tem trazido à cena social um personagem que permaneceu por muito tempo na invisibilidade, ou seja, a mulher alcoólica. Este estudo, de caráter qualitativo, baseado na literatura sócioantropológica sobre o processo saúdeadoecimento e na perspectiva de gênero, investiga a dependência alcoólica entre as mulheres. Seu objetivo foi compreender os sentidos e os significados da dependência alcoólica feminina entre homens e mulheres alcoólicos em processo de recuperação em Alcoólicos Anônimos. Para tanto, fez-se trabalho de campo em 5 unidades de AA próximas da região central do município de Campinas. Durante o período de março a setembro de 2013, ocorreram visitas regulares aos grupos e 16 entrevistas com alguns de seus participantes, sendo 8 homens e 8 mulheres entrevistadas. Os resultados alcançados no trabalho de campo apontam para um crescimento da busca por ajuda institucional para tratamento antialcoólico entre as mulheres. Dentre outros achados, verificou-se que embora tenha ocorrido uma ampliação do acesso das mulheres nos espaços de tratamento, ainda permanece forte algumas representações sociais negativas e preconceituosas acerca da dependência alcoólica feminina que constrange a inserção e a permanência das mulheres nos cinco serviços de recuperação alcoólica estudados. Apesar disso, a partir da análise da instituição AA e das entrevistas de seus membros, homens e mulheres, o AA não deve ser considerado nem conservador e nem sexista em sua origem. Ou seja, ao que tudo indica, as concepções negativas atreladas às mulheres alcoólicas advém do universo social externo ao grupo, incorporado e reproduzido pelos alcoólicos, especialmente os homens, resultando, assim, na dificuldade de integração das mulheres nos grupos analisados. Os resultados desta pesquisa dialogam com a produção e o debate acadêmico sobre a mulher alcoólica no campo do estudo de álcool. Revelando que não necessariamente tem havido um crescimento da dependência alcoólica entre as mulheres, mas sim, um aumento da visibilidade social do grupo / ABSTRACT: Epidemiological studies have shown an increase in alcohol consumption and alcohol dependence among women, a problem that had so far been predominantly associated with the male population. This investigation not only starts with that realization but also problematizes it as we observe that the female emancipation process has brought to the social scene a character that had long remained invisible: the alcoholic woman. This qualitative study, based on the socio-anthropological literature about the health-illness process and on the gender perspective, looks into female alcohol dependence. It aims to understand the senses and meanings of female alcohol dependence among alcoholic men and women in Alcoholics Anonymous rehabilitation. To that end, field work has been carried out at five AA units located close to the central region of the city of Campinas. From March to September, 2013, the groups were regularly visited and 17 of their participants (8 men and 9 women) were interviewed. The field work results point to an increase in women\'s search for institutional help to get anti-alcoholic treatment. Other findings indicate that, even though women\'s access to spaces of anti-alcoholic treatment has broadened, some negative and prejudiced social representations about female alcohol dependence remain strong and constrain women\'s insertion and permanence in the five alcohol rehabilitation services that were studied. Nevertheless, the analysis of the AA institution and its members\' interviews, both men and women, suggests that the AA is neither conservative nor sexist in its origin. It seems that the negative conceptions regarding alcoholic women emerge from the social universe external to the group, incorporated and replicated by the alcoholics, particularly men, making it difficult for women to integrate into the studied groups. The research findings establish a dialogue with the academic production and debate on the alcoholic woman in the alcohol study field. They reveal that, rather than an increase in alcohol dependence among women, there has been a rise in the social visibility of this group
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O retorno à norma: o alcoolismo como produto da vida cotidiana / The return to norm: alcoholism as a product of everyday lifeFrancisco, Vinícius Nascimento 11 September 2015 (has links)
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Previous issue date: 2015-09-11 / This study aims to analyze a particular course of action understood as a disease by the medical science and an offense to the structuring of processes ordered face-to-face interaction in everyday life. Alcoholism was selected for the theoretical and empirical object as the social experiences of members of self-help groups that acquired a social significance in recent decades: the "Alcoholics Anonymous" AA. The AA is a physical space that apprehends alcoholism as a matter related to the daily lives of men and women stigmatized as drunk. The AA members strive gradually in overlay alcoholism with a language related to the reorganization of their everyday lives. . In the first instance, we address the intrinsic relationship between the systemic world of science, its way to make sense to alcoholism (rational construction of the disease conception) and their acceptance of disability on other approaches to the problem of excessive alcohol consumption in social life. In a second step, we show the historical and political development of the United States and favorable social conditions for the emergence of a movement that understands alcoholism from the public discussion on the way to the common good of society. On a third occasion, we study the social experiences of AA members and the construction of belief in alcoholism within the group as a spring abnormality of disruption of the privacy of its visitors. We understand therefore that alcoholism for AA membership is a fact that hindered his performances in everyday social relations - and will continue blocking if nothing is done to understand the abnormality of those who constantly drink in everyday life. The work was based on qualitative methodologies such as case study, having been selected for the AA your research, semi-structured interviews with the group members, systematic observation of AA meetings and document analysis used by its frequenters / O presente trabalho analisa uma determinada maneira de agir, entendida como doença pela ciência médica, e uma ofensa à estruturação dos processos ordenados de interação face a face na vida cotidiana. Selecionou-se o alcoolismo para o estudo teórico e como objeto empírico as experiências sociais dos membros dos grupos de autoajuda que adquiriu uma importância social nas últimas décadas: os Alcoólicos Anônimos A.A. O A.A é um espaço físico que apreende o alcoolismo como uma questão relacionada ao cotidiano de homens e mulheres estigmatizados como bêbados. Os membros do A.A esforçam-se, gradativamente, em revestirem o alcoolismo com uma linguagem relacionada à reorganização de suas vidas cotidianas. Num primeiro instante, abordamos as intrínsecas relações entre o mundo sistêmico da ciência, sua forma em atribuir sentido ao alcoolismo (construção racional da concepção de doença) e sua incapacidade de aceitação diante de outras abordagens sobre o problema do consumo excessivo de álcool na vida social. Num segundo momento, mostramos o desenvolvimento histórico e político dos Estados Unidos e as condições sociais propícias para o surgimento de um movimento que compreende o alcoolismo, a partir da discussão pública em torno do caminho rumo ao bem comum da sociedade. Numa terceira ocasião, estudamos as experiências sociais dos membros do A.A e a construção da crença no alcoolismo dentro do grupo como uma anormalidade nascente da desestruturação da vida privada de seus frequentadores. Entendemos, pois, que o alcoolismo, para os membros do A.A, é um fato que obstruiu suas atuações nas relações sociais cotidianas e que continuará obstruindo, caso nada seja feito para se entender a anormalidade daqueles que bebem constantemente na vida cotidiana. O trabalho se apoiou em metodologias qualitativas como o Estudo de Caso, tendo sido selecionado o A.A para sua pesquisa, entrevistas semiestruturadas com os membros do grupo, observação sistemática das reuniões do A.A. e análise de documentos utilizados por seus frequentadores
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"Utilização do acamprosato no tratamento de dependentes de álcool" / Use of acamprosate in the treatment of alcohol-dependent outpatientsBaltieri, Danilo Antonio 25 November 2002 (has links)
A eficácia e a segurança do acamprosato foram avaliadas no tratamento ambulatorial de setenta e cinco pacientes do sexo masculino, com idade entre 18 e 59 anos, com diagnóstico de dependência de álcool pelo CID-10. O estudo foi controlado duplo-cego, com duração de 24 semanas. Transtornos clínicos e/ou psiquiátricos que necessitassem de internação, uso de medicação psiquiátrica, quadros psicóticos prévios independentes do consumo de álcool e hipersensibilidade ao acamprosato foram critérios de exclusão. Após um período de desintoxicação de uma semana, os pacientes foram divididos aleatoriamente em dois grupos: o primeiro grupo recebeu acamprosato (6 comprimidos de 333 mg por dia durante 12 semanas), e o segundo recebeu placebo (6 comprimidos por dia durante 12 semanas). Após as primeiras 12 semanas, os pacientes continuaram o tratamento por mais 12 semanas sem uso de medicação. Os grupos foram comparados quanto a sintomas depressivos, uso de álcool, efeitos colaterais das medicações, exames laboratoriais e tempo de abstinência contínuo. 25% dos pacientes que estavam recebendo acamprosato e 20% dos pacientes que estavam recebendo placebo foram excluídos do seguimento. Os pacientes que receberam acamprosato mostraram maior taxa de abstinência contínua no final das 24 semanas de tratamento quando comparados aos que receberam placebo (57% versus 25%, p = 0,014), e tiveram uma duração média de abstinência contínua de 18,8 semanas enquanto o grupo placebo teve uma duração média de abstinência contínua de 12 semanas (p = 0,003). Efeitos colaterais foram registrados. O acamprosato mostrou-se ser seguro e eficaz no tratamento de pacientes dependentes de álcool e na manutenção da abstinência durante 24 semanas. / The efficacy and security of acamprosate were evaluated in the treatment of 75 men, between 18 and 59 years of age, with diagnosis of alcohol dependence by ICD-10. It was a double-blind, placebo controlled study, 24 weeks long. Patients with disorders that should be treated in an inpatient setting, using psychiatric medications, relating previous psychoses without alcohol use and with hipersensibility to acamprosate were excluded. After a one-week detoxification period, the patients were randomily divided in two groups: the first group received acamprosate (6 tablets of 333 mg a day during 12 weeks) and the second group received placebo (6 tablets during 12 weeks). After the first 12 weeks, the patients continued the follow-up for 12 weeks more without medication. The groups were compared in terms of depressive symptoms, use of alcohol, side effects of medications and laboratory tests. 25% of patients who were receiving acamprosate dropped out, whereas 20% of the placebo-treated patients dropped out of the study. Patients who were receiving acamprosate showed significantly higher continuous abstinence rate within the 24 weeks of treatment compared with patients who were assigned to placebo treatment (57% versus 25%, p = 0,014), and they had significantly longer mean abstinence duration of 18,8 weeks versus 12 weeks abstinent (p = 0,003). Few side effects were related. Acamprosate proved to be safe and an effective aid in the treatment of alcohol dependent patients and in maintaining the abstinence of patients during 24 weeks.
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O retorno à norma: o alcoolismo como produto da vida cotidiana / The return to norm: alcoholism as a product of everyday lifeFrancisco, Vinícius Nascimento 11 September 2015 (has links)
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Previous issue date: 2015-09-11 / This study aims to analyze a particular course of action understood as a disease by the medical science and an offense to the structuring of processes ordered face-to-face interaction in everyday life. Alcoholism was selected for the theoretical and empirical object as the social experiences of members of self-help groups that acquired a social significance in recent decades: the "Alcoholics Anonymous" AA. The AA is a physical space that apprehends alcoholism as a matter related to the daily lives of men and women stigmatized as drunk. The AA members strive gradually in overlay alcoholism with a language related to the reorganization of their everyday lives. . In the first instance, we address the intrinsic relationship between the systemic world of science, its way to make sense to alcoholism (rational construction of the disease conception) and their acceptance of disability on other approaches to the problem of excessive alcohol consumption in social life. In a second step, we show the historical and political development of the United States and favorable social conditions for the emergence of a movement that understands alcoholism from the public discussion on the way to the common good of society. On a third occasion, we study the social experiences of AA members and the construction of belief in alcoholism within the group as a spring abnormality of disruption of the privacy of its visitors. We understand therefore that alcoholism for AA membership is a fact that hindered his performances in everyday social relations - and will continue blocking if nothing is done to understand the abnormality of those who constantly drink in everyday life. The work was based on qualitative methodologies such as case study, having been selected for the AA your research, semi-structured interviews with the group members, systematic observation of AA meetings and document analysis used by its frequenters / O presente trabalho analisa uma determinada maneira de agir, entendida como doença pela ciência médica, e uma ofensa à estruturação dos processos ordenados de interação face a face na vida cotidiana. Selecionou-se o alcoolismo para o estudo teórico e como objeto empírico as experiências sociais dos membros dos grupos de autoajuda que adquiriu uma importância social nas últimas décadas: os Alcoólicos Anônimos A.A. O A.A é um espaço físico que apreende o alcoolismo como uma questão relacionada ao cotidiano de homens e mulheres estigmatizados como bêbados. Os membros do A.A esforçam-se, gradativamente, em revestirem o alcoolismo com uma linguagem relacionada à reorganização de suas vidas cotidianas. Num primeiro instante, abordamos as intrínsecas relações entre o mundo sistêmico da ciência, sua forma em atribuir sentido ao alcoolismo (construção racional da concepção de doença) e sua incapacidade de aceitação diante de outras abordagens sobre o problema do consumo excessivo de álcool na vida social. Num segundo momento, mostramos o desenvolvimento histórico e político dos Estados Unidos e as condições sociais propícias para o surgimento de um movimento que compreende o alcoolismo, a partir da discussão pública em torno do caminho rumo ao bem comum da sociedade. Numa terceira ocasião, estudamos as experiências sociais dos membros do A.A e a construção da crença no alcoolismo dentro do grupo como uma anormalidade nascente da desestruturação da vida privada de seus frequentadores. Entendemos, pois, que o alcoolismo, para os membros do A.A, é um fato que obstruiu suas atuações nas relações sociais cotidianas e que continuará obstruindo, caso nada seja feito para se entender a anormalidade daqueles que bebem constantemente na vida cotidiana. O trabalho se apoiou em metodologias qualitativas como o Estudo de Caso, tendo sido selecionado o A.A para sua pesquisa, entrevistas semiestruturadas com os membros do grupo, observação sistemática das reuniões do A.A. e análise de documentos utilizados por seus frequentadores
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