Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-03-20T22:18:32Z No. of bitstreams: 1 LaysPinheiroDeMedeiros_DISSERT.pdf: 2931997 bytes, checksum: bc17f556882bb10726ee26a84f71d688 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-03-23T21:35:22Z (GMT) No. of bitstreams: 1 LaysPinheiroDeMedeiros_DISSERT.pdf: 2931997 bytes, checksum: bc17f556882bb10726ee26a84f71d688 (MD5) / Made available in DSpace on 2017-03-23T21:35:22Z (GMT). No. of bitstreams: 1 LaysPinheiroDeMedeiros_DISSERT.pdf: 2931997 bytes, checksum: bc17f556882bb10726ee26a84f71d688 (MD5) Previous issue date: 2016-12-02 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / Estomia ? uma abertura criada artificialmente a partir do trato gastrointestinal, ou trato urin?rio, para o abd?men, por onde ocorre o desvio e elimina??o do fluxo de fezes e urina. A estomia demanda atendimento a diversas necessidades adaptativas que envolvem aspectos fisiol?gicos, psicol?gicos e sociais. Isso requer a atua??o da enfermagem voltada para a promo??o da adapta??o da pessoa com estomia. A fim de sistematizar o cuidado ? pessoa estomizada, com vistas ? adapta??o eficaz e consequente melhoria da qualidade de vida, a enfermagem pode utilizar o Modelo de Adapta??o de Roy (MAR), que cont?m seis etapas do processo de enfermagem. O objetivo desse estudo foi construir e validar o conte?do de um instrumento para medir o n?vel de adapta??o do estomizado, com base no MAR. Trata-se de um estudo metodol?gico que ser? desenvolvido em duas etapas: constru??o dos itens do instrumento a partir das defini??es dos constructos, e a aplica??o do instrumento aos ju?zes. As defini??es constitutivas e operacionais foram feitas a partir da literatura e o processo de valida??o foi realizado por meio do ?ndice de Validade de Conte?do (IVC). Foram selecionados 116 ju?zes para a etapa de valida??o, dos quais nove foi realizada pela avalia??o de nove ju?zes, Todos responderam que consideram importante que o enfermeiro conhe?a o processo adaptativo da pessoa estomizada, a maioria referiu se sentir preparado para assistir a pessoa estomizada, incluindo as necessidades adaptativas e tamb?m conheciam o Modelo de Adapta??o de Roy. O primeiro modo adaptativo avaliado pelos ju?zes foi o fisiol?gico, no qual metade itens apresentaram IVC acima de 0,80 e, quanto ? perman?ncia do item no modo inicialmente alocado, apenas 3 (18,7%) tiveram 100% de repostas favor?veis ? manuten??o do item no modo. Dos 17 itens do modo autoconceito, Apenas 4 (23,5%) dos itens obtiveram IVC acima de 0,8 e 8 (47%) apresentam respostas 100% favor?veis ? manuten??o do item no modo. No modo fun??o de papel, 4 (100%) dos itens apresentaram IVC acima de 0,8 e 2 (50%) itens apresentaram total recomenda??o de perman?ncia no modo. Por fim, no modo interdepend?ncia, 3 (42,9%) itens apresentaram IVC acima de 0,8 e 4 (57,1%) tiveram todas as respostas voltadas para a manuten??o do item no modo. Ao final dessa etapa, 7 itens foram retirados do instrumento, dois foram agrupados em um s? e um foi alocado em outro modo diferente do preliminar. A vers?o final do instrumento possui 34 itens no total, sendo 11 no modo fisiol?gico, 14 no autoconceito, 4 no fun??o de papel e 5 no interdepend?ncia. Conclui-se que os itens constru?dos para compor a ENAE possuem validade de conte?do. / Ostomy is an opening that is artificially created from the gastrointestinal tract, or urinary tract, to the abdomen, from where it occurs a detour and the elimination of stool and urine. The ostomy?s construction requires several adaptive needs which involve from physiological aspects to psychological and social demands. This way, it is needed the performance of a nurse guided toward an improvement of the adaptation of the person with an ostomy. In order to systematize the care to the person with an ostomy, aiming an effective adaptation and consequent enhancement on their quality of life, the nurse can use Roy?s adaptation model (RAM), which is described on six stages of the nursing process. The first two are consisted on the stage of gathering data on stimulus and behaviors, of which will guide the subsequent stages. Therefore, the objective of this study is to construct and validate the content of the instrument entitled as ?Scale of the adaptation level of the person with an ostomy (ENAE). It is about a methodological study that will be developed on two phases: The first is consisted on the construction of the instrument?s items from the construct?s definitions, and the second will be based on the evaluation phase of the judges. The constitutive and operational definitions were made from the literature and the validation process will be analyzed using the Content Validation Index (CVI). 116 judges were selected for the validation phase, of which? by the evaluation of nine judges. Everyone answered that they considered as important that the nurse must know the adaptive process of the person with an ostomy, most of them referred that felt prepared to help the person with an ostomy, including the adaptive needs and also have to know Roy?s Adaptive Model. The first adaptive model evaluated by the judges was the physiological one, of which 8 (50%) items showed and CVI bigger than 0.80 and, regarding the item?s continuity on the initially allocated mode, only 3 (18.7%) had 100% of favorable answers about the item?s keeping on the mode. From the 17 items on the self ? concept mode, only 4 (23.5%) of the items had CVI above 0.8 and 8 (47%) showed answers 100% favorable to the item?s keeping on the mode. On the paper function mode, 4 (100%) of the items showed CVI above 0.8 and 2 (50%) of the items showed total recommendation regarding the continuity on the mode. Finally, on the interdependence mode, 3 (42.9%) items showed CVI above 0.8 and 4 (57.1%) had all the answers guided toward the item?s keeping on the mode. At the end of this stage, 7 items were removed from the instrument, two were grouped in only one and one was allocated on another mode different from the preliminary mode. The instrument?s final version has 34 items, being 11 on the physiological mode, 14 on the self ? concept mode, 4 on the paper function and 5 on the interdependence mode. Regarding the study?s limitations, the response?s reduced quantitative, and its delay, by part of the judges made it more difficult to construct these results. In addition to this, many of them did not comprehend some orientations, which made it harder to interpret some data. This project was approved by the Commission of Ethics in Research of UFRN, report number 421.342, CAAE of number 19866413.3.0000.5537.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-04-03T19:14:19Z No. of bitstreams: 1 AmandaDeLourdesBernardoGuerra_DISSERT.pdf: 2783809 bytes, checksum: b565043a1fe85b3b1136bf29b7674e77 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-04-04T21:08:48Z (GMT) No. of bitstreams: 1 AmandaDeLourdesBernardoGuerra_DISSERT.pdf: 2783809 bytes, checksum: b565043a1fe85b3b1136bf29b7674e77 (MD5) / Made available in DSpace on 2017-04-04T21:08:48Z (GMT). No. of bitstreams: 1 AmandaDeLourdesBernardoGuerra_DISSERT.pdf: 2783809 bytes, checksum: b565043a1fe85b3b1136bf29b7674e77 (MD5) Previous issue date: 2016-08-30 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES) / A avalia??o neuropsicol?gica das fun??es executivas (FE) tem sido objeto de interesse crescente de pesquisas. No Brasil, os testes utilizados para avaliar FE em crian?as geralmente s?o adapta??es de tarefas para uso em adultos e com alta complexidade, perdendo a capacidade de discriminar fun??es e d?ficits espec?ficos. Al?m disso, identifica-se significativa dispers?o de testes e protocolos padronizados utilizados na avalia??o das FE em crian?as, dificultando a realiza??o de estudos multic?ntricos, bem como compreens?o do impacto de quadros cl?nicos sobre o desenvolvimento e funcionamento das FE. Esse estudo tem como objetivo traduzir e adaptar o protocolo FEE (Roy, Le Gall, Roulin, & Fournet, 2012) para o portugu?s/Brasil. O protocolo ? composto por um conjunto de testes e escalas de avalia??o neuropsicol?gica das FE destinado a crian?as e adolescentes entre seis e 15 anos e constru?do com o objetivo de modificar e/ou melhorar, em termos de materiais, instru??es e/ou corre??es, os principais paradigmas e testes de avalia??o das FE, com o intuito de suprir as insufici?ncias das tarefas existentes e adaptar tarefas consagradas internacionalmente. A adapta??o transcultural do FEE foi realizada pelo modelo proposto por Borsa, Dam?sio, & Bandeira (2012), constitu?do de seis etapas (1- Tradu??o do instrumento para o novo idioma, 2- S?ntese das Vers?es , 3- Avalia??o da S?ntese por Experts, 4- Avalia??o pelo P?blico-Alvo, 5- Tradu??o Reversa-Back-translation, 6- Estudo-Piloto). Inicialmente, o instrumento original passou por duas tradu??es independentes da l?ngua francesa ao portugu?s brasileiro. Na etapa 2 (S?ntese das Vers?es), participaram tr?s ju?zes, psic?logos, doutorandos e experts em avalia??o neuropsicol?gica, assim como os autores pesquisadores da pesquisa. Os ju?zes julgaram boa equival?ncia experiencial, idiom?tica e sem?ntica. Por?m, ainda na etapa 2 foram realizadas altera??es para tornar a vers?o em portugu?s mais adaptada para a popula??o-alvo. Na etapa 3 (Avalia??o da S?ntese por Experts), participaram tr?s ju?zes, professores doutores de diferentes regi?es do pa?s, que avaliaram a estrutura, o formato, as instru??es e a abrang?ncia e adequa??o das express?es contidas nos itens que constituem o instrumento. A concord?ncia entre ju?zes foi avaliada pelo Kappa de Cohen (0.4945), que indicou concord?ncia moderada. Na etapa 4, participaram 30 crian?as e adolescentes, sendo10 crian?as na faixa et?ria entre seis e sete anos, 10 crian?as entre 10 e 11 anos e 10 adolescentes entre 15 e 16 anos. De forma geral, observou-se compreens?o ampla das instru??es do protocolo. Na etapa 5 foi realizada back-translation por duas tradu??es independentes do portugu?s para a l?ngua francesa e ap?s s?ntese das tradu??es o instrumento foi enviado aos autores que julgaram o instrumento adequado. Por fim, a etapa 6 (estudo piloto) consistiu na aplica??o do protocolo em 60 crian?as e adolescentes entre seis e 15 anos, de escolas p?blicas e escolas particulares da rede de ensino do Natal. O instrumento mostrou-se adequado para avalia??o das FE no contexto cultural brasileiro. A continuidade deste projeto possibilitar? ampliar a compreens?o do desenvolvimento das FE da inf?ncia ? adolesc?ncia bem como da semi?tica dos dist?rbios das FE. Por fim, destaca-se ainda a possibilidade de realiza??o de estudos transculturais acerca do desenvolvimento das FE. / Currently, the interest on executive functions (EF) neuropsychological assessment researches is increasing. However, in Brazil, standardized tests and protocols used on the evaluation of children's EF are disperse, turning it difficult to realize multicenter studies and identify regional characterization. Furthermore, tests used on children's EF evaluation are usually adaptations of tasks used on adults, showing little ecological validity, and are designed to be hard, weakening its capability of discriminating specific functions and deficiencies, since different executive components are required in a single task. The aim of this study is the translation and adaptation of the French protocol FEE (Roy et al., 2012) to Portuguese/Brazil. FEE is an EF neuropsychological assessment protocol aiming children and adolescents between six and 15 years old, designed to modify and/or enhance, in terms of materials, instructions, procedures and/or corrections, the main paradigms and EF evaluation tests. It intends to fill the insufficiencies of existing tasks and to adapt internationally acclaimed tasks. Cultural adaptation of the FEE will be conducted according to the model proposed by Borsa, Dam?sio, & Bandeira, (2012), structured around six steps (translation of the instrument, synthesis of the versions, synthesis evaluation by experts, evaluation by the target audience, back-translation, pilot study). Firstly, the original instrument was subjected to two independent translations from the mother language (French) to Brazilian Portuguese. For the second step (Synthesis of the Versions), three judges ? all psychologists, doctorate students and experts in neuropsychological assessment ? participated, as well as the original research authors. Judges rated the experimental, idiomatic and semantical equivalence as good. However, still in step 2, modifications were made in the Portuguese version in order to better adjust it to the target-population. In step 3 (Synthesis evaluation by experts), three different judges ? PhD scholars from different regions of Brazil ? participated, evaluating structure, format, instructions, and comprehensiveness and adequateness of the expressions used on each item of the instrument. Agreement between judges was evaluated by Cohen?s Kappa (0.4945), indicating moderate agreement. In step 4 (Evaluation by the target population), 30 children and adolescents participated, with 10 children aged between six and seven years old, 10 children aged between 10 and 11 years old and 10 adolescents aged between 15 and 16 years old. Generally, it was observed broad comprehensiveness of protocol instructions. In step 5 the instrument was back-translated twice, independently, from Brazilian Portuguese to the mother language (French). After the back-translations synthesis, the instrument was sent back to the original authors, who judged it adequate. Finally, step 6 (pilot study) consisted in administering the battery to 60 children and adolescents aged between six and 15 years old, from public and private schools from Natal?s educational system. The instrument proved adequate for evaluation of EF in Brazilian cultural context. The further development of this project will enable to widen comprehensiveness on children and adolescents EF, as well as on the semiotics of EF disturbs. Lastly, there is also the possibility of performing transcultural studies on EF development.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-03T12:09:00Z No. of bitstreams: 1 HedyanneGuerraPereira_DISSERT.pdf: 2086737 bytes, checksum: 40c97cbf5242cc256c76b7cf51a6f606 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-05T12:11:17Z (GMT) No. of bitstreams: 1 HedyanneGuerraPereira_DISSERT.pdf: 2086737 bytes, checksum: 40c97cbf5242cc256c76b7cf51a6f606 (MD5) / Made available in DSpace on 2017-07-05T12:11:18Z (GMT). No. of bitstreams: 1 HedyanneGuerraPereira_DISSERT.pdf: 2086737 bytes, checksum: 40c97cbf5242cc256c76b7cf51a6f606 (MD5) Previous issue date: 2017-01-30 / Introdu??o: O estudo do enfrentamento de situa??es estressoras na inf?ncia ? considerado importante, visto que ao longo dessa etapa do desenvolvimento, a crian?a aprende as modalidades b?sicas da exist?ncia humana, que influenciam na forma com que ela se relaciona com o mundo e integra suas experi?ncias. Nesse contexto, a literatura enfatiza a necessidade de aprofundar a potencialidade de medidas de enfrentamento infantil baseadas no autorrelato. Diante disso, considera-se oportuno disponibilizar vers?es brasileiras de ferramentas advindas de investiga??es bem estabelecidas em outras culturas, como o instrumento Kidcope, medida de autorrelato, que investiga estrat?gias de enfrentamento utilizadas por crian?as e adolescentes de 7 a 12 anos em situa??es estressoras. Objetivo: Adaptar transculturalmente o Kidcope para o Portugu?s (Brasil). M?todo: Pesquisa metodol?gica, transversal. Realizou-se equival?ncia conceitual e de itens, sem?ntica e operacional entre o instrumento original e a vers?o brasileira; e a equival?ncia de mensura??o. Resultados: Evidenciou-se boa equival?ncia conceitual e de itens, al?m de sem?ntica, entre os itens do instrumento original e das retrotradu??es, sobretudo quanto ? d?ade T2 ? R2. Quanto ? equival?ncia operacional, foram inclu?das 33 crian?as, que avaliaram o instrumento como adequado e compreens?vel. Na de mensura??o, participaram 150 crian?as, com m?dia de idade de aproximadamente 9 anos. Verificou-se que as estrat?gias mais utilizadas s?o as de enfrentamento ativo e de evita??o, consideradas mais eficazes pelos participantes. Por meio do Alfa de Cronbach, constatou-se valor 0,315 de consist?ncia interna para os itens do Kidcope. Conclus?o: Apesar das limita??es relacionadas ? baixa confiabilidade do instrumento, considera-se que ele cumpre o objetivo a que se prop?e. Configurando-se como um instrumento de rastreio de estrat?gias de enfrentamento de crian?as e adolescente diante de situa??es estressoras, tanto em contextos cl?nicos quanto de pesquisa. / Introduction: The study of the coping in childhood is considered important, as children learn the basic modes of human existence during this developmental stage, which will influence the way infants relate to the world and integrate their experiences. Given this scenario, the literature emphasizes the importance of deepen the knowledge about measurement instruments for children's coping strategies. Therefore, it is considered appropriate to provide Brazilian versions deriving from well-established researches in other cultures, such as the Kidcope self-report instrument, which allows to measure coping strategies used by children and adolescents aged 7 to 12 in stressful situations. Objective: To translate and carry out cross-cultural adaptation of such instrument to Brazilian portuguese. Method: This is a methodological and traversal research. Equivalence of items and concepts as well as semantics and operation has already been performed between the original instrument and the Brazilian version; and the measurement equivalence. Results: A good level of equivalence has been observed, including comparisons between the original instrument and the Brazilian version translated back to original language; this is particularly true regarding T2-R2 dyads. In regard to the operational equivalence, 33 children evaluated the adapted instrument as adequate and easy to understand. In the measurement, 150 children participated, with a mean age of approximately 9 years. It was verified that the strategies most used are those of active coping and avoidance, considered more effective by the participants. By means of the Cronbach's alpha, the value of 0.315 internal consistency was found for Kidcope items. Conclusion: Despite the limitations related to the low reliability of the instrument, it is considered that it meets the proposed objective. Configuring yourself as an instrument for screening coping strategies of children and adolescents in the face of stressful situations, both in clinical and research contexts.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-04T14:02:47Z No. of bitstreams: 1 LeonidasPetrucioDutraPedrosa_DISSERT.pdf: 2026244 bytes, checksum: 03b3c4c138e8e0e14d1abb33e974deb1 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-13T11:22:26Z (GMT) No. of bitstreams: 1 LeonidasPetrucioDutraPedrosa_DISSERT.pdf: 2026244 bytes, checksum: 03b3c4c138e8e0e14d1abb33e974deb1 (MD5) / Made available in DSpace on 2017-07-13T11:22:26Z (GMT). No. of bitstreams: 1 LeonidasPetrucioDutraPedrosa_DISSERT.pdf: 2026244 bytes, checksum: 03b3c4c138e8e0e14d1abb33e974deb1 (MD5) Previous issue date: 2017-02-22 / As 17 cidades inseridas nas microrregi?es do Serid? oriental e ocidental formam a regi?o denominada de Serid? do Rio Grande do Norte ? RN, inserida no semi?rido setentrional nordestino, caracterizado por apresentar fen?menos clim?ticos extremos como os longos per?odos de estiagem. Al?m disso, historicamente, o referido espa?o apresenta baixos ?ndices de desenvolvimento econ?mico em compara??o com as ?reas mais desenvolvidas do estado do RN, localizadas na faixa litor?nea leste, principalmente aquelas que englobam a Regi?o Metropolitana de Natal. Tal conjuntura, que alia problem?ticas ambientais com condi??es prec?rias de vida e baixos ?ndices de desenvolvimento humano, acabou contribuindo para a forma??o de uma gama de munic?pios que apresentam uma popula??o com alta vulnerabilidade socioambiental e com baixa capacidade de resposta aos longos per?odos de escassez de ?gua. Tais fatores constru?ram dificuldades para o desenvolvimento da reprodu??o social de sua popula??o e contribuiu para que ampla gama de indiv?duos adotasse a emigra??o da regi?o como uma forma de adapta??o ao fen?meno. Dessa forma, o supracitado espa?o apresenta uma din?mica populacional que nos permite analisar, a partir dos perfis socioecon?micos dos emigrantes e da popula??o n?o migrante, se a op??o por migrar funciona como forma de resposta ?s vulnerabilidades socioambientais presentes nesta regi?o. Nesse sentido, a fim de realizar uma leitura demogr?fica desse espa?o geogr?fico, ser?o analisados os perfis socioecon?micos como renda per capita, n?vel de instru??o e idade dos emigrantes e n?o-migrantes da regi?o, j? que esses s?o elementos utilizados em grande parte das pesquisas para mensura??o da vulnerabilidade. / The 17 cities located in the eastern and western Serid? microregions form the Serid? region of Rio Grande do Norte - RN is inserted in the northern semiarid Northeast, which is characterized by extreme climatic phenomena such as long periods of drought. In addition, historically, this area presents low rates of economic development compared to the more developed areas of the state of the RN, located in the eastern coastal range, especially those that encompass the Metropolitan Region of Natal. This situation, which combines environmental problems with poor living conditions and low human development rates, has contributed to the formation of a range of municipalities that present a population with high socio-environmental vulnerability and a low capacity to respond to long periods of water scarcity. These factors created difficulties for the development of social reproduction of its population and contributed to the wide range of individuals adopting the emigration from the region as a form of adaptation to the phenomenon. Thus, the aforementioned space presents a population dynamics that allows us to analyze, from the socioeconomic profiles of the emigrants and the non-migrant population, whether the option to migrate works as a response to the socio-environmental vulnerabilities present in this region. In this sense, in order to carry out a demographic reading of this geographic space, socioeconomic profiles such as per capita income, level of education and age of migrants and non-migrants of the region will be analyzed, since these elements are used in a wide range of research on vulnerability measurement.

Submitted by Ricardo Cedraz Duque Moliterno (ricardo.moliterno@uefs.br) on 2016-03-14T23:59:46Z No. of bitstreams: 1 Disserta??o pronta- nova com ficha.pdf: 2003328 bytes, checksum: 36b0f4f6ccb2f233288ee9d258c01e1f (MD5) / Made available in DSpace on 2016-03-14T23:59:46Z (GMT). No. of bitstreams: 1 Disserta??o pronta- nova com ficha.pdf: 2003328 bytes, checksum: 36b0f4f6ccb2f233288ee9d258c01e1f (MD5) Previous issue date: 2014-12-19 / L'imageriepermet ? l'homme de tracersespropresimages de lavie. Lesimagesdansce conte de f?esprendl'homme ? parleraveclefantastique, lacr?ation et larecr?ationdesimagesavecsoncontexte, une activit?fondamentalepourled?veloppement de l'humanit?. Les contes de f?es, d?sles premiers jours de r?citsoraux, le dialogue avecleshommesdansdiff?rentscontextesafin que, par leursadaptations ? ?trereconnus. L'histoire de Chaperonrougeseraprisedanscetterecherche, ? partir desimagescr??es par Gustave Dor? (XIXesi?cle) et d?voil?e par contemporan?it? que vos images se manifestentdanslefilmRedRidingRood(2011). Comprendrerleprocessus d'adaptationexistant entre l'histoire et sesimages de diff?rentes ?poquesc?stfaistr?simportant. Poureffectuerl'analyse, allonsmarcher ? traverslafor?t-Girl Chaperon Rouge et leloupseracelleobserv?edanssonimageriedes formes vari?es. / O imagin?rio permite que o homem trace suas pr?prias imagens da vida. O imagin?rio presente nos contos de fadas leva o homem a dialogar com o fant?stico, criar e recriar imagens com o seu contexto, uma atividade fundamental para o desenvolvimento da humanidade. Os contos de fadas, desde os prim?rdios das narrativas orais, dialogam com homens em diferentes contextos para que atrav?s de suas adapta??es seja reconhecida. O conto Chapeuzinho Vermelho ser? tomado nesta pesquisa, a partir das imagens criadas por Gustave Dor? (S?culo XIX) e desvelado pela contemporaneidade que atrav?s de suas imagens se manifestam no filme A garota da capa vermelha (2011). Busca- se compreender o processo de adapta??o existente entre o conto e suas imagens de diferentes ?pocas. Para a realiza??o da an?lise, passear-se-? pela floresta da menina Chapeuzinho Vermelho e do lobo mau, queser?o vistos em suas variadas formas imag?ticas.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-05-04T17:15:51Z No. of bitstreams: 1 TES_HENRIQUE_VIEIRA_FIGUEIRO_COMPLETO.pdf: 4680551 bytes, checksum: 8695b78fe6812f4690586975941c4c31 (MD5) / Made available in DSpace on 2017-05-04T17:15:51Z (GMT). No. of bitstreams: 1 TES_HENRIQUE_VIEIRA_FIGUEIRO_COMPLETO.pdf: 4680551 bytes, checksum: 8695b78fe6812f4690586975941c4c31 (MD5) Previous issue date: 2016-03-11 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Conselho Nacional de Pesquisa e Desenvolvimento Cient?fico e Tecnol?gico - CNPq / In the past 10 years, high throughput sequencing has revolutionized evolutionary biology. With the technical advances that emerged with the genome sequencing of model species, it is now possible to apply these techniques to taxonomic groups without any previously available genetic resources. Complete genome sequencing and reduced representation methods have enabled us to explore deeper evolutionary questions, such as detecting ancient hybridization and signatures of selection on a genomic scale. Among the groups that could benefit from these methods is the Panthera genus. The group is composed by five species (P. onca, P. tigris, P. leo, P. pardus and P. uncia), all of which are large felids that exert important ecological role as apex predators in their habitats. Their low densities, alarming rates of habitat loss and chronic conflict with humans, all of them are threatened with extinction in the wild and thus important targets for conservation. One of the species in this group, the jaguar (P. onca), is the only member of the genus currently present in the Neotropical region, and the focus of our study. The jaguar has a color pattern similar to that of the leopard, but a much more robust constitution, with massive jaws and shorter limbs. The present study aims to characterize for the first time the jaguar genome, and to perform comparative analyses with the genomes from all other Panthera species. In addition, we seek to perform population genomic analyses with Brazilian jaguar populations and search for signatures of divergent selection in different regions. We have sequenced four genomic libraries, with an estimated coverage depth of 84x. The complete genome sequence allowed the annotation of 25,441 genes and the description of other genomic features (e.g. ncRNA, microsatellites, numts). Additionally, we have sequenced the genome of a leopard at low coverage, with an estimated depth of 25x. With the addition of these two genomes, we were able obtain a genomic data set containing all five Panthera species, which was used to perform phylogenetic discordance analyses and to detect signatures of selection using a dataset encompassing 13,143 orthologous genes. We were able to demonstrate the presence of hybridization events during the speciation process of the species, as well as signatures of selection in genes potentially involved in important characteristics of these iconic animals. Among them, the jaguar?s robust build, the social behavior of lions, cold environment adaptations in the snow leopard and the tiger?s stripes. Using an exome capture approach, we performed a population genomics study targeting jaguar populations from different Brazilian biomes. In addition to assessments of genetic diversity and population structure, we detected signals of local adaptation using multiple methods. Among the obtained results is the presence of genes under selection that are related to energetic metabolism in the Amazon, body development in the Pantanal and immunity in the Atlantic Forest. Additionally, we observed several pigmentation-related genes under selection in different biomes. Those genes affect not only pigmentation, but also have pleiotropic effects in development and immunity routes. Overall, these results help to understand the evolutionary processes that have shaped the adaptation of Panthera species, and particularly the jaguar, to the environments where they currently live. / Nos ?ltimos 10 anos, o sequenciamento gen?mico de alto desempenho revolucionou a biologia evolutiva. Com os avan?os gerados pelo sequenciamento do genoma completo de esp?cies modelo, agora ? poss?vel aplicar essas t?cnicas em animais com praticamente nenhum recurso gen?tico dispon?vel. O sequenciamento completo de genomas, bem como o uso de t?cnicas de representa??o reduzida, permitem explorar quest?es evolutivas complexas como, por exemplo, detec??o de hibrida??o e assinaturas de sele??o natural em uma escala gen?mica. Dentre os grupos taxon?micos que podem se beneficiar de tais t?cnicas est? o g?nero Panthera. O grupo ? composto por cinco esp?cies atuais (P. onca, P. tigris, P. leo, P. pardus e P. uncia), todas elas apresentando grande porte e atuando como predadores de topo nos ambientes que ocupam. Devido ?s baixas densidades, alarmante perda de habitat e constantes conflitos com humanos, o n?vel de amea?a em que essas esp?cies se encontram ? preocupante. Dentre as esp?cies do grupo, est? a on?a-pintada (P. onca), ?nica integrante do g?nero na regi?o Neotropical e o principal foco deste trabalho. Nesse sentido, o presente estudo busca caracterizar pela primeira vez o genoma da on?a-pintada, incluindo an?lises comparativas com as outras quatro esp?cies do g?nero. Al?m disso, o trabalho tem como objetivo avaliar as popula??es de on?a no Brasil e buscar assinaturas de sele??o divergente nos biomas que ela ocupa. Para o sequenciamento do genoma da esp?cie, foram utilizadas quatro bibliotecas gen?micas, com uma cobertura estimada de 84x. A sequ?ncia do genoma completo permitiu a anota??o de 25.441 genes e a descri??o de outros componentes do genoma (p.ex. ncRNA, microssat?lites, numts). Adicionalmente, foi sequenciado o genoma de um leopardo (P. pardus) com cobertura estimada de 25x. Com esses dois novos genomas, completou-se um conjunto abrangendo todas as cinco esp?cies do g?nero, permitindo a realiza??o de an?lises de discord?ncia filogen?tica para o grupo e detec??o de sele??o positiva utilizando um conjunto de 13.143 genes ort?logos. Foi poss?vel demonstrar eventos de hibrida??o durante o processo de especia??o das esp?cies do g?nero, bem como sinais de sele??o positiva em genes envolvidos em caracter?sticas que se destacam nos grandes fel?deos. Entre eles, fen?tipos potencialmente afetados por genes sob sele??o incluem o cr?nio e membros robustos da on?a-pintada, o comportamento social no le?o, adapta??o ao frio no leopardo das neves e a presen?a de listras no tigre. Com o uso de captura de exoma, que tem como objetivo o sequenciamento do conjunto de exons da esp?cie, foi poss?vel realizar uma nova avalia??o das caracter?sticas gen?ticas de popula??es de on?a-pintada, bem como a detec??o de assinaturas de adapta??o local. Entre os resultados obtidos est? a presen?a de genes sob sele??o relacionados com metabolismo energ?tico em popula??es da Amaz?nia, adapta??es relacionadas com desenvolvimento corporal no Pantanal e imunidade na Mata Atl?ntica. Adicionalmente, foram observados diversos genes de pigmenta??o com assinaturas de sele??o em diferentes biomas. Esses genes, al?m de afetarem a colora??o dos animais, possuem efeitos pleiotr?picos no desenvolvimento e imunidade da esp?cie. Esses resultados auxiliam no entendimento dos processos evolutivos que moldaram a adapta??o das esp?cies do g?nero, e em especial a on?a pintada, aos ambientes que elas ocupam atualmente.

Made available in DSpace on 2016-04-04T18:28:14Z (GMT). No. of bitstreams: 1 MARCIA CALIXTO DOS SANTOS.pdf: 1003356 bytes, checksum: c4b5e00e909e2559f64ab1568facdc7b (MD5) Previous issue date: 2013-12-11 / Chronic renal failure (CRF) is the gradual and progressive loss of kidney functions, which can promote severe restrictions and psychosocial impact into the individual?s life, even risking to lead her or him to death. Its high prevalence in the current context defines it as a worldwide public health problem. The present study aimed to evaluate the degree of association between adaptive efficacy, psychopathological symptoms and stress levels in chronic renal failure patients and verify whether these variables could predict their adaptive efficacy. We adopted the concept of adaptive efficacy, by Ryad Simon, a measure of the quality of the individual's responses to situations of their day-by-day. The sample was composed of 50 patients with chronic renal failure, of both sexes, attended hemodialysis unit of a general hospital inland city of S?o Paulo. The assessment instruments used were: EDAO-AR - Self-Report Scale of Adaptation, designed to evaluate the quality of the adaptation of the sector Affective-Relational (AR) and Productivity (Pr); EAS- 40 - Assessment Symptoms Scale-40, which assesses the severity of psychopathological symptoms according to four dimensions: psychoticism, obsessiveness-compulsiveness, somatization and anxiety; ISSL Lipp Stress Symptoms Inventory, which assesses the symptoms of stress in the psychological and physical, besides the person?s stress phase. The results suggested that the participants were divided into effectively adapted (76%) and poorly ineffectively adapted (24%). Regarding psychopathological symptoms, the average score was 0,41 (? 0,33) (cutoff 1[E1]); 56% showed no stress and 44 % had stress, in the Resistance Phase (34%) with predominant psychological symptoms of stress (73%). The values of the Spearman Rank Correlation (?) confirmed the initial hypotheses as they pointed to significant and negative associations between psychopathological symptoms and adaptive efficacy and between stress and adaptive efficacy; significant positive association between psychopathological symptoms and stress. The structural equations modeling (SEM) suggested that psychopathological symptoms predict psychological stress and adaptive efficacy, however physical stress and phases of stress are not depicted as predictors of adaptive efficacy. / A insufici?ncia renal cr?nica (IRC) consiste na perda gradativa e progressiva das fun??es dos rins, o que pode causar restri??es severas e impacto psicossocial ao indiv?duo, ou at? mesmo lev?-lo ? morte. Sua alta preval?ncia no contexto atual a define como um problema de sa?de p?blica em n?vel mundial. O presente estudo teve como objetivo avaliar o grau de associa??o entre a efic?cia adaptativa, os sintomas psicopatol?gicos e os n?veis de stress de pacientes renais cr?nicos e verificar se estas vari?veis poderiam predizer a sua efic?cia adaptativa. Adotou-se o conceito de efic?cia adaptativa, de Ryad Simon, uma medida da qualidade das respostas do indiv?duo ?s situa??es de seu dia-a-dia. A amostra ficou constitu?da por 50 pacientes com insufici?ncia renal cr?nica, de ambos os sexos, atendidos na unidade de hemodi?lise de um hospital geral do interior de S?o Paulo. Os instrumentos de avalia??o utilizados foram: EDAO-AR - Escala Diagn?stica Adaptativa Operacionalizada de Autorrelato, que permite avaliar a qualidade da efic?cia adaptativa do setor Afetivo-Relacional (A-R) e Produtividade (Pr); EAS-40 - Escala de Avalia??o de Sintomas 40, que avalia a severidade de sintomas psicopatol?gicos segundo quatro dimens?es: psicoticismo, obsessividade-compulsividade, somatiza??o e ansiedade; ISSL Invent?rio de Sintomas de Stress para Adultos de Lipp, que avalia a presen?a de sintomas de stress nos ?mbitos psicol?gico e f?sico, al?m da fase do stress em que a pessoa se encontra. Os resultados apontaram que os participantes ficaram distribu?dos em adapta??o eficaz (76%) e adapta??o ineficaz leve (24%). Quanto aos sintomas psicopatol?gicos, o escore m?dio foi de 0,41 (? 0,33) (ponto de corte 1[E1]); 56% n?o apresentaram stress e 44% apresentaram stress, dos quais 34% na Fase de Resist?ncia e com predom?nio de sintomas psicol?gicos do stress (73%). As correla??es por postos de Spearman (?) confirmaram as hip?teses iniciais, indicando associa??es significantes e negativas entre sintomas psicopatol?gicos e efic?cia adaptativa e entre stress e efic?cia adaptativa; associa??o significante positiva entre sintomas psicopatol?gicos e stress. A modelagem de equa??es estruturais (MEE) indicou que sintomas psicopatol?gicos predizem o stress psicol?gico e a efic?cia adaptativa, entretanto o stress f?sico e as fases do stress n?o se configuram como preditores da efic?cia adaptativa.

Made available in DSpace on 2016-04-04T18:29:37Z (GMT). No. of bitstreams: 1 Luis Fernando Galvao.pdf: 399706 bytes, checksum: ab7fc74b6a16a19214fcee83ce181af7 (MD5) Previous issue date: 2007-07-16 / This study refers to the psychometric properties of the Defensive Style Questionnaire- 40 (DSQ-40) for the imprisoned population. It discusses the relevance in the use of precise and valid psychological measures in the prison context, according to a perspective of psychosocial reintegration. The concepts of the positive Psychology, resilience and defenses are used as an epistemic-theorical basis. Afterwards, it discusses the use of defense measuring instruments as a means to estimate the ways individuals deal with the demands come from reality. It emphasizes the use of the DSQ-40, which is not only simple to use and correct, but also shows satisfactory psychometric characteristics, according to national and international studies. The instrument is a questionnaire self-report like and it contains 40 items developed to evaluate the resulting conscious defense mechanisms; it aims to identify the typical style which people deal conscious or unconsciously- with their conflicts, according to the postulation that they are able to communicate precisely through their behaviors. The DSQ-40 evaluates 20 defenses, divided in three factors: mature, neurotic and immature. The instrument applied to a sample of 271 prisoners (208 men and 63 women), who live in three prisons located in S?o Paulo and Mato Grosso do Sul States. The precision of the instrument was checked through the Pearson s co-relation coefficient; the results pointed that only the immature factor showed time stability. The internal consistence of the instrument was estimated through the Cronbach s Alpha coefficient and the average co-relation of the items, but only the immature factor showed expressive values (Alpha = 0,80). The criterion validity was estimated according to co-relation coefficient proposed by Spearman and it was used as a convergent criterion of the scores obtained by the Resilience Scale (n=46); The Symptom Evaluation Scale SES-40 (n=38) as a discriminating validity criterion. The study of the construct validity was done through the procedures of factorial analysis according to the analysis of the main components and varimax rotation method; three interpretative factors were obtained (25,98% of the variances): the immature, the mature and the neurotic factors, which correspond to the study of validation done with the clinical sample. Ten defenses showed a satisfactory factorial importance (over 0,30) in the immature factor, two in the mature factor and three in the neurotic factor. The results suggest the need of modifications and adaptations in the items that measure the mature and neurotic defenses in order to try to expand the respective reliable coefficients and the validity of the construct. / Trata-se do estudo das propriedades psicom?tricas do Defensive Style Questionnaire-40 (DSQ-40) para a popula??o prisional. Discute-se inicialmente, a relev?ncia da utiliza??o de medidas psicol?gicas v?lidas e precisas no contexto prisional, segundo uma perspectiva de reintegra??o psicossocial. Os conceitos de psicologia positiva, resili?ncia e defesas s?o utilizados como fundamenta??o te?rico-epist?mica. Discute-se, a seguir, a utiliza??o de instrumentos de medida das defesas como um meio de aferir as formas atrav?s das quais os sujeitos lidam com as demandas da realidade. Enfatiza-se a utiliza??o do DSQ-40, que al?m de ser de f?cil aplica??o e corre??o, apresenta caracter?sticas psicom?tricas satisfat?rias, segundo estudos nacionais e internacionais com diferentes amostras. O instrumento ? um question?rio de tipo self-report, com 40 itens desenvolvidos para avaliar os derivativos conscientes dos mecanismos de defesa; objetiva identificar o estilo caracter?stico de como as pessoas lidam, consciente ou inconscientemente com seus conflitos, segundo o pressuposto de que s?o capazes de comunicar com precis?o seus comportamentos. O DSQ-40 avalia 20 defesas, divididas em tr?s fatores: maduro, neur?tico e imaturo. O instrumento foi aplicado a uma amostra de 271 presidi?rios (208 homens e 63 mulheres) reclusos em tr?s unidades prisionais localizadas nos Estados de Mato Grosso do Sul e S?o Paulo. A precis?o do instrumento foi estimada atrav?s do coeficiente de correla??o de Pearson; os resultados indicaram que somente o fator imaturo apresentou estabilidade temporal. A consist?ncia interna do instrumento foi aferida atrav?s do coeficiente alfa de Cronbach e da correla??o m?dia dos itens, mas somente o fator imaturo apresentou valores significativos (? = 0,80). A validade convergente foi estimada segundo o coeficiente de correla??o de postos de Spearman, tendo sido utilizado como crit?rio a Escala de Resili?ncia (n = 46). Para o estudo da validade discriminante utilizou-se a Escala de Avalia??o de Sintomas EAS-40 (n = 38). O estudo de validade de construto foi realizado atrav?s do procedimento de an?lise fatorial segundo o m?todo de an?lise dos componentes principais e rota??o varimax. Foram obtidos tr?s fatores interpret?veis (25,98% da vari?ncia): fator imaturo, fator maduro e fator neur?tico. Do ponto de vista estrutural (itens que comp?em cada fator) os resultados s?o muito semelhantes aos obtidos no estudo brasileiro com amostra cl?nica, para a adapta??o do instrumento para o portugu?s. Dez defesas apresentaram carga fatorial satisfat?ria (superior a 0,30) no fator imaturo, duas no fator maduro e tr?s no fator neur?tico. Os resultados sugerem a necessidade de modifica??es e adapta??es nos itens que medem as defesas neur?ticas e maduras, no sentido de procurar ampliar os respectivos coeficientes de fidedignidade e de validade de constructo.

Submitted by PPG Gerontologia Biom?dica (geronbio@pucrs.br) on 2019-03-13T19:56:19Z No. of bitstreams: 1 VIANA_SUSY_ANE_RIBEIRO_DIS.pdf: 3189179 bytes, checksum: d1f3103752ccad4f16b0aa1e9a5b0437 (MD5) / Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2019-03-21T13:45:47Z (GMT) No. of bitstreams: 1 VIANA_SUSY_ANE_RIBEIRO_DIS.pdf: 3189179 bytes, checksum: d1f3103752ccad4f16b0aa1e9a5b0437 (MD5) / Made available in DSpace on 2019-03-21T14:28:42Z (GMT). No. of bitstreams: 1 VIANA_SUSY_ANE_RIBEIRO_DIS.pdf: 3189179 bytes, checksum: d1f3103752ccad4f16b0aa1e9a5b0437 (MD5) Previous issue date: 2017-03-01 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The construction and adaptation of instruments are necessary to aggregate methods of psychological evaluation that aim to investigate aspects of health promotion and quality of life, it is particularly noticed the importance of new instruments that contemplate the elderly. The literature has shown gratitude as a protective factor and as a provider of subjective well-being for the elderly. Therefore, the central axis of this study is the cross-cultural translation and adaptation of the Cuestion?rio de Gratitud de 20 ?tems (G-20) prepared by Bernab?-Valero et al (2014) in Spain, directing the instrument to the elderly Brazilian population. It was chosen as the method of adaptation the ten-step process of Beaton et al. Al (2002): 1) Conceptual definitions and literature review; 2) Contact with the author; 3) Translation; 4) Synthesis of translations; 5) Backtranslation; 6) Analysis of Judges; 7) Modifications and readjustments; 8) Pilot Study; 9) Final version readjustments and application in a larger sample; And, 10) Psychometric Analyzes of the instrument. The Brazilian version will maintain the G-20 nomenclature, adding the name "G-20-IB Elderly Gratitude Scale" (Brazilian Elderly) in its final title. Six bilingual translators participated in the study, of which 3 were Brazilian and 3 were foreigners (stage 3); Seven judges, two specialists and five non-specialists (stage 6); 38 elderly (step 8); And 80 elderly (stage 9), from three Brazilian states. Descriptive statistical analyzes (average, standard deviation, percentages and percentiles) were performed for the analysis among judges. The concordance index will be evaluated using the Fagundes method and the Kappa index. Internal consistency was measured using Cronbach's Alpha. The G-20 IB presented suitability between judges concordance analyzes, where k = 1. As well as, presented Alpha of Cronbach equal to ? = 0.81 demonstrating optimal adequacy, suggesting that the instrument has a good level of convergence between the items. Further studies are still needed for the psychometric validation of the G-20 IB, however this study was able to present a premise of other studies that may still be performed with this new evaluation instrument. Gratitude is linked directly as we shape interpersonal relationships and personal existential senses. It has a motivating and pro-social factor, which intensifies emotions of subjective well-being towards healthy aging. The contribution of this study would be to help in the elaboration of new knowledge and intervention techniques for the elderly that prioritize the use of preventive and non-pharmacological tactics. / A constru??o e adapta??o de instrumentos s?o necess?rias para agregar m?todos de avalia??o psicol?gica que visem investigar aspectos de promo??o de sa?de e qualidade de vida, em particular percebe-se a import?ncia de novos instrumentos que contemplem o idoso. A literatura tem apresentado a gratid?o como fator protetivo e de promo??o de sa?de e bem-estar subjetivo para os idosos. Portanto, o eixo central desse estudo ? a tradu??o e adapta??o transcultural do Cuestion?rio de Gratitud de 20 ?tems (G-20) elaborado por Bernab?-Valero et al (2014) na Espanha, direcionando o instrumento para a popula??o brasileira idosa. Foi escolhido como m?todo de adapta??o de instrumento o processo dividido em dez etapas de Beaton e outros (2002): 1) Defini??es conceituais e revis?o da literatura; 2) Contato com a autora; 3) Tradu??o; 4) S?ntese das Tradu??es; 5) Retrotradu??o (backtraslation); 6) An?lise dos Ju?zes; 7) Modifica??es e reajustes; 8) Estudo Piloto; 9) Reajustes da vers?o Final e aplica??o em uma amostra maior; e, 10) An?lises Psicom?tricas do instrumento. A vers?o brasileira ir? manter a nomenclatura G-20, sendo acrescido o nome ?Escala de Gratid?o para Idosos G-20-IB? (Idosos Brasileiros) em seu t?tulo final. Participaram do estudo seis tradutores bil?ngues, sendo tr?s brasileiros e tr?s estrangeiros (etapa 3); Sete ju?zes, dois especialistas e cinco n?o especialistas (etapa 6); 38 idosos (etapa 8); e 80 idosos (etapa 9), provenientes de tr?s estados do Brasil. Foram realizadas an?lises estat?sticas descritivas (m?dia, desvio-padr?o, percentuais e percentis), para a an?lise entre ju?zes o ?ndice de concord?ncia foi avaliado atrav?s do m?todo de Fagundes e do ?ndice de Kappa, a consist?ncia interna foi medida atrav?s do Alpha de Cronbach. A G-20 IB apresentou adequabilidade nas an?lises de concord?ncia interju?zes, sendo k=1. Tamb?m apresentou Alpha de Cronbach igual a ?= 0.81 demonstrando ?tima adequa??o, sugerindo que o instrumento possui um bom n?vel de converg?ncia entre os itens. Ainda se fazem necess?rios mais estudos para a valida??o psicom?trica da G-20 IB, mas esse estudo p?de apresentar uma premissa de outros estudos que ainda poder?o ser realizados com esse novo instrumento de avalia??o. A gratid?o est? ligada diretamente com a maneira que moldamos as rela??es interpessoais e sentidos existenciais pessoais, ela possui um fator motivador e pr?-social, que intensifica emo??es de bem-estar subjetivo para um envelhecimento bem sucedido. O aporte desse estudo seria o de poder contribuir na elabora??o de novos conhecimentos e de t?cnicas de promo??o de sa?de e de interven??o para o idoso, que priorizem o uso de t?ticas preventivas e n?o farmacol?gicas.

Made available in DSpace on 2015-04-14T13:35:12Z (GMT). No. of bitstreams: 1 431165.pdf: 850340 bytes, checksum: a2e688c3555bab8a8fa5c9cdf12fa3d4 (MD5) Previous issue date: 2011-03-29 / Introdu??o: A doen?a renal cr?nica ? um grave problema de sa?de p?blica no pa?s. D?ficit cognitivo ? comum em pacientes com insufici?ncia renal cr?nica terminal e depress?o ? uma condi??o prevalente na doen?a renal cr?nica terminal. Objetivo: avaliar a fun??o cognitiva de pacientes com insufici?ncia renal cr?nica submetidos ? di?lise peritoneal no Hospital S?o Lucas da PUC e Hospital Benefic?ncia Portuguesa de Pelotas. Materiais e M?todos: Estudo transversal controlado. Foram inclu?dos pacientes em tratamento para doen?a renal cr?nica terminal, em di?lise peritoneal h? pelo menos tr?s meses, com idade acima de 18 anos, e pontua??o no Mini Exame do Estado Mental acima de 18. Foram exclu?dos pacientes com dem?ncia pr?via conhecida, hist?ria de acidente vascular cerebral, doen?a aguda, e hospitalizado com dificuldades de aprendizagem conhecidas. O grupo controle incluiu parentes saud?veis de pacientes em Di?lise Peritoneal (DP) e Hemodi?lise (HD), mesma idade e n?vel s?cio-educativo. Todos os participantes foram submetidos a uma ?nica aplica??o de testes psicom?tricos no momento da consulta cl?nica ou agendados. Os testes utilizados foram a Escala de Intelig?ncia Wechsler para Adultos (WAIS-III), o Invent?rio de Depress?o Beck (BDI) e o Mini-Exame do Estado Mental (MEEM). Participaram 60 indiv?duos, 30 pacientes em DP e 30 indiv?duos saud?veis. Resultados: Os grupos n?o foram diferentes quanto a escores do MEEM (DP 25,9+5,4, Controle 26,8+3,3, p=0,462) e do WAIS-III, com exce??o do ?ndice da velocidade de processamento (DP 90 +19,6, controle 99 + 14,3, p=0,039). Os pacientes em DP apresentaram o escore BDI significativamente maior que os controles (DP=14, IIQ=6-23; Controle=9, IIQ=4-13; p=0,010). Ajustando os dados para presen?a de depress?o e atividade laboral, verificou-se que o ?ndice de velocidade de processamento dos pacientes foi 12,7 pontos menor que nos controles. Conclus?o: O ?ndice de velocidade de processamento da escala WAIS-III foi menor nos pacientes em DP do que nos controles. Os demais aspectos da fun??o cognitiva de pacientes em DP n?o foram diferentes de controles com mesma idade e n?vel s?cio-econ?mico-educacional