Sedan de första mobila spelen släpptes har tekniken utvecklats och så kallade exergames, vilka ställer krav på fysisk förflyttning för att avancera blir allt vanligare. År 2016 släpptes mobilspelet Pokémon Go och har, mätt med avkastning och popularitet, dominerat den mobila spelmarknaden. Det har ur ett forskningsperspektiv tagits fram ett flertal modeller där framgångsfaktorer som kännetecknar ett populärt spel för att attrahera användare presenterats. Tidigare studier hävdar dessutom att AR-teknologin, som tillämpas i Pokémon GO, kan främja fysisk aktivitet, kreativitet och utbildning samt introducera nya sätt för social interaktion.Syftet med denna studie är att urskilja vilka framgångsfaktorer Pokémon GO har för att locka samt behålla sina användare. För att besvara studiens frågeställning har en enkätundersökning genomförts där 61 deltagare svarat på frågor rörande deras åsikter om spelet. Resultatet av användarens egna upplevelser och åsikter har analyserats för att sedan dras i parallell med erkända forskningsmodeller.Studiens resultat visar på ett flertal anledningar till att användare lockats till spelet och att de dynamiska egenskaper som implementerats i Pokémon Go återfinns i ett flertal av de forskningsteorier som presenterats i studien. Nyfikenheten för teknologin, nostalgin för spelkonceptet samt den sociala interaktionen med andra spelare är några av dessa för att exemplifiera. Vidare har studien visat att spelet brister i en del egenskaper som forskare, med sina modeller, menat vara väsentliga. Hinder där spelet inte lyckats motivera användaren till att fortsätta spela har exempelvis varit av den karaktär där spelare distraherats, tappat fokus och med detta intresset för att fortsätta spela. / Since the first mobile games were released, the technology has been developed and the so-called exergames that make demands on physical movement to advance are becoming more common. In 2016, the mobile game Pokémon Go was released and has, measured by yield and popularity, dominated the mobile gaming market. From a research perspective, several models have been developed in which success factors required by a popular game to attract users are presented. Previous studies also argue that the augmented reality (AR) technology applied in the Pokémon GO can promote physical activity, creativity and education, and introduce new ways of social interaction.The purpose of this study is to distinguish which success factors Pokémon GO has to attract and retain its users. To do this, a questionnaire survey was conducted in which 61 participants answered questions regarding their views on the game. The result of the user's own experiences and opinions has been analyzed and then drawn in parallel with recognized research models.The study's results show on several grounds that users were attracted to the game and that the dynamic features implemented in Pokémon Go are found in a number of the research theories presented in the study. The curiosity of the technology, the nostalgia for the game concept and the social interaction with other players are some of these to exemplify. Furthermore, the study has shown that the game lacks in some properties that researchers, with their models, mean to be essential. Obstacles where the game failed to motivate the user to continue playing have, for example, been of the character in which players are distracted, lost focus and with this the interest in continuing to play.

Studien undersöker hur olika politiska aktörer uttrycker sig om den svenska statens förmåga att upprätthålla ett våldsmonopol och vad detta kan få för implikationer för Sverige. Studien vilar på Max Webers definition av staten som ett mänskligt samhälle som framgångsrikt hävdar monopolet på det legitima användandet av fysiskt våld inom ett givet territorium. Med denna definition som grund genomförs en diskursanalys av den svenska statens brister i debatten kring ”no-go zoner” i svenska utanförskapsområden. Mer specifikt analyserar uppsatsen ett nationellt och internationellt urval politiska aktörer som i den politiska debatten antingen legitimerar eller de-legitimerar den svenska staten i Webers mening. Utifrån konstruktivistiska antaganden om att statens existens är socialt konstruerad och diskursivt formerad visar resultaten att aktörernas sätt att uttrycka sig i debatten kring svenska utanförskapsområden ger grogrund för ett ifrågasättande av statens existens

Many researchers across a wide range of disciplines have turned to gene expression anal- ysis to aid in predicting and understanding biological outcomes and mechanisms. Because genes are known to work in a dependent manner, it’s common for researchers to first group genes in biologically meaningful sets and then test each gene set for differential expression. Comparisons are made across different treatment/condition groups. The meta-analytic method for testing differential activity of gene sets, termed multi-variate gene set testing (mvGST), will be used to provide context for two persistent and problematic issues in gene set testing. These are: 1) gathering organism specific annotation for non-model organisms and 2) handling gene annotation ambiguities. The primary purpose of this thesis is to explore different gene annotation gathering methods in the building of gene set lists and to address the problem of gene annotation ambiguity. Using an example study, three different annotation gathering methods are proposed to construct GO gene set lists. These lists are directly compared, as are the subsequent results from mvGST analysis. In a separate study, an optimization algorithm is proposed as a solution for handling gene annotation ambiguities.

The purpose of this essay is to examine the scientific relations between Sweden and America, later USA, through the letter correspondence between Nils Collin and his fellow “scientists” in Sweden and America between 1770–1830. By examining the letters though three different theoretical lenses: Scientific persona, gift exchange and the geography of knowledge with the concepts of centers and peripheries, the inquiry shows us how the scientific relations between the two countries developed and changed during the investigated time period, thus adapting themselves to the political developments that created an international scientific arena instead of the earlier nation neutrality. The letter correspondence reflects the increase in communication between Swedish scientists and American scientists as well as between Swedish institutions such as The Royal Swedish Academy of Sciences and The American Philosophical Society with Nils Collin as their main go-between. The letters indicate that Nils Collin’s role within the communication network changed with time and that he became an enabler of knowledge circulation between Sweden and the US though his position and many contacts. Lastly, by examining the letters, we can see how the increased communication as well as Nils Collin’s changing role plays part in the American scientific and national development that ultimately changed the earlier ideas of centers and peripheries of knowledge.

Beef and milk production industries represent the largest agricultural industries in the United States with a retail equivalent value of approximately $112 billion (USDA, 2008). Infertility is the major problem for mammalian reproduction. In the United States approximately 66% of cows are bred by Artificial Insemination (AI), but only ~50% of these inseminations result in successful pregnancies. Infertility can occur either from male factor (spermatozoon) or female factor (oocyte) and male contributes approximately 40% of cases. Infertility costs the producer approximately $5 per exposed cow for every 1% reduction in pregnancy rate. In spite of its millions of dollars in economic impact, the precise molecular events/mechanisms that determine the fertilizing potential of an oocyte and spermatozoon are not well defined. The thesis of my doctoral dissertation is that proteomics-based “systems biology” modeling of bovine oocyte and spermatozoon can facilitate rapid understanding of fertility. To test this thesis, I needed to first identify the proteins associated with bovine oocyte and its associated cumulus cells, and spermatozoon. The next step was functional annotation of the experimentally confirmed proteins to identify the major functions associated with the oocyte, cumulus cells and spermatozoon, and finally, generate a proteomics based systems biology model of bovine oocyte and cumulus cell communication and male fertility. The results of my dissertation established the methods that provide afoundation for high-throughput proteomics approaches of bovine oocyte and cumuluscell biology and allowed me to model the intricate cross communication between oocyte and cumulus cells using systems biology approaches. Proteomics based systems biology modeling of oocytes and cumulus cells identified the signaling pathways and proteins associated with this communication that may have implications in oocyte maturation. In addition, systems biology modeling of differential spermatozoa proteomes from bulls of varying fertility rates enabled the identification of putative molecular markers and key pathways associated with male fertility. The ultimate positive impact of these results is to facilitate the field of biomedical research with useful information for comparative biology, better understanding of bovine oocyte and spermatozoon development, infertility, biomarker discovery, and eventually development of therapies to treat infertility in bovine as well as humans.

The aim of this thesis is to evaluate the level of motor skills in children and adolescents dealing with judo and taekwondo and to determine whether the level of motor skills differs between children with a suspected risk of ADHD (Attention Deficit Hyperactivity Disorder) compared to children without this risk. Another aim of this study is to evaluate the level of attention and find out whether it correlates with the level of motor skills. A total of 65 probands aged 9-13 years participated in the study. The experimental groups consisted of children competing in judo (n = 35), children practicing taekwondo (n = 19) and children attending taekwondo classes in physical education and hobby groups (n = 11). The Movement Assessment Battery for Children 2 test was chosen to test motor skills. To detect a suspected risk of ADHD was used the Test Go / NoGo and the level of attention was tested by theTest of attention d2. A significant difference in favour of judists was found between the results of motor skills of children and adolescents in comparison with the racing group of taekwondists (p = 0.045) and also in the results of individual components, namely in the balance component (p = 0.051). A significant difference was found in motor skills among children with a suspected risk of ADHD compared to...

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Merry-Go-Round is a realistic adolescent novella that looks at true problems young adults can face. The protagonist, Amy, is ten-year-old girl who meets a boy, Ben, of the same age at the hotel where her mother works. Amy and Ben become fast friends. Amy's mother is involved in an abusive relationship and Ben's mother is dying of cancer. Through the relationship formed between the children, they learn how to survive by sharing their difficulties and working them out. The realistic, troublesome situations faced by the main characters of Merry-Go-Round will help readers graduate smoothly on the next level of reading.

This study investigates how James Baldwin thought about history and treats his first novel as an important document in extricating his construct of the past. A close reading of the work reveals that it is an examination rather than a symptom of two powerful forces that dominate Baldwin's psychology, his father and his history. James Baldwin felt the individual interpretation of one's experience is just as important as the experience itself. The novel is an informative exposition of how people interpret their experience and how that interpretation affects their psychology. Through Go Tell It on the Mountain Baldwin recreates the personal history he knows little about and is afforded a psychological freedom he would have never known without its completion. This study illuminates how useful fiction is to one's historical conscience and perception. The research exposes how important a sense of history is to the formation of identity.

Little Milligan Elementary School in rural Carter County, Tennessee was provided with health literacy resources in the form of health education Go-Packs––easily implementable lessons contained in a small storage tote––as part of the community project requirement of the James H. Quillen College of Medicine Rural Primary Care Track Curriculum. These Go-Packs included detailed lesson plans and accompanying materials that were designed to facilitate health education in the classrooms by providing easily deployable lessons for the teachers to utilize. Four Go-Packs were provided for hygiene, oral health, tobacco use, and nutrition that teachers used to augment instruction during teachable moments that arose in their classrooms. Our objective was to determine whether the development and implementation of these Go-Packs increased the amount of health education delivered to the students and determine what barriers persist to provide health education in the classroom. Participants were randomly assigned a number which they placed on their pre and post surveys. A focus group was also conducted to better understand the faculty’s experience utilizing the Go-Packs and where improvements could be made. A paired sample t-test showed no significant differences in pre and post attitudes of teachers at the school. The focus group and survey questions identified the need to improve the usability of specific Go-Packs, map the Go-Packs to state mandated curriculums and target Go-Pack usage towards non-core instructors.