Submitted by Nadir Basilio (nadirsb@uninove.br) on 2016-06-07T18:10:41Z No. of bitstreams: 1 Narciso Bastos Gomes.pdf: 1629149 bytes, checksum: 351c44b1d0c962cdbe06544920bf9db8 (MD5) / Made available in DSpace on 2016-06-07T18:10:41Z (GMT). No. of bitstreams: 1 Narciso Bastos Gomes.pdf: 1629149 bytes, checksum: 351c44b1d0c962cdbe06544920bf9db8 (MD5) Previous issue date: 2014-12-16 / This study presents a proposal of a regional model of innovation system idealized for sheep industry from Mato Grosso do Sul (MS) state – Brazil – bonded to the breendig of pantaneira sheep. Public and private agents, universities, financial institution and R&D centers composes such innovation system, which is committed through the innovation with the development of a nation, region or economy sector. According to the Schumpeter approach, the economic development is only possible under the effort of entrepreneurs, either by a set of agents committed with the creation of new products, processes and technologies or by their ability of disseminating them, which results in both technical and economic development. From Schumpeter approach and the Evolutionary Theory of Technological Development there has been a great advance on the recognition of the innovation system as a structure needed to revolutionize and develop nations, regions or sector. From the original idea of Schumpeter in pointing out the innovation as a driving force for the economic development and the innovation system as a strategy to develop learning and technologies through innovation, there has been a current evolution by some prospective studies focusing on the “design” and by the proposition of innovation system models of countries, regions and sectors. Thus, this study presents the regional innovation system as a strategy for the development of the pantaneira sheep industry productive chain in the state of MS. Since 2005, this activity has attracted the attention of public and private agents comprised with the breeding and slaughter, commerce, improvement of the animals as well as development and adaptation of such breed to the regional environment. Even in the 8thnational position in sheep flock and the 2nd regional position, MS state does not stand out as a great consumer nor as producer of meat, wool and other sheep sub-products. Aiming the standard breed, the regional agents of development has turned their attention to the pantaneira breed, by adopting some techniques of breeding, fattening, management, power and mortality reduction. This manuscriptis featured as single case study according to Yin perspective, with a qualitative and exploratory nature. The interview performed with eleven innovation agents chosen by snowball technique furnished the information that were analyzed via Content Analysis under Bardin (2009) perspective. We concluded that currently there is in the state the basis for the structuration of a engaged for the modernization of this regional activity through the strategies regional innovation system whose agents are the own actors that compose the sheep productive chain, who have been of professionalization and innovation under the neo-Schumpeter approach. / Este estudo apresenta a proposta de modelo do sistema regional de inovação idealizado para a ovinocultura do estado de Mato Grosso do Sul-MS e sua associação ao desenvolvimento da ovelha pantaneira. Um sistema de inovação é constituído por agentes públicos e privados, universidades, instituições financeiras e centros de P&D, empenhados em desenvolver por meio da inovação uma nação, região ou um setor da economia. Na abordagem Schumpeteriana, o desenvolvimento econômico torna-se possível pelos esforços de empresários empreendedores ou via um conjunto de agentes empenhados em criar novos produtos, processos e tecnologias ou pela capacidade de difundi-los e de gerar desenvolvimento técnico e econômico. Na abordagem neo-Schumpeteriana e na Teoria Evolucionária do desenvolvimento tecnológico, avançou-se no reconhecimento do sistema de inovação como uma estrutura necessária para revolucionar e desenvolver nações, regiões ou setores. Da ideia original de Schumpeter em apontar a inovação como força motriz para o desenvolvimento econômico e o sistema de inovação como estratégia para desenvolver aprendizagem e tecnologias por meio da geração de inovações, evoluiu-se para os dias atuais estudos prospectivos enfocando o “desenho” e proposição de modelos de sistemas de inovação de países, regiões ou setores. Assim, este estudo apresenta o Sistema Regional de Inovação como estratégia para o desenvolvimento da cadeia produtiva da ovinocultura e a criação da raça pantaneira do estado de Mato Grosso do Sul. Desde 2005, esta atividade tem recebido atenção de agentes públicos e privados envolvidos com a criação, abate, comercialização, aprimoramento dos animais, desenvolvimento e adaptação das raças ao ambiente sulmatogrossense. Mesmo ocupando a 8ª posição em rebanho de ovinos no país e a 2ª posição na Região Centro-Oeste, o estado não se destaca como grande consumidor e produtor de carne, lã e outros subprodutos ovinos. Para se chegar a uma raça padrão, os agentes de desenvolvimento regional têm se voltado para o desenvolvimento da ovinocultura pantaneira adotando novas técnicas de cria, recria, engorda, manejo, alimentação e redução da mortalidade. Este estudo caracteriza-se como estudo de caso único na perspectiva de Yin, de cunho qualitativo e exploratório. As entrevistas foram conduzidas com onze agentes de inovação previamente escolhidos pela técnica snowball. As informações obtidas nas entrevistas foram tratadas e analisadas via Análise de Conteúdo na perspectiva de Bardin (2009). Concluiu-se que atualmente já existe no estado as bases para a estruturação de um sistema regional de inovação em que os agentes de inovação são os próprios atores que compõem a cadeia produtiva da ovinocultura e que vêm se empenhando para modernizar a atividade regionalmente por meio de estratégias de profissionalização e inovação nos moldes da abordagem neo-Schumpeteriana.

Innovation in healthcare is a central way of coping with the changes affecting the healthcare system through the megatrends of demographic change, digitalization as well as the opportunities in the life-sciences sector and the “-omics” subjects. Due to the multiple facets of the topic, research on innovation in healthcare is diverse and draws insights from systems theory, management theory, human resources, innovation and change management. While the literature on innovation in healthcare has grown steadily in the last 20 years and publications on pharmaceutical and medical device innovation, health technology assessment strategies, or digital innovations have increased significantly, other areas such as sectoral health innovation systems, the creation and implementation of innovation in hospitals still remain fairly uncharted. Applying established concepts such as systems of innovation theory, mass customization theory or management of employee involvement in innovation activities to the healthcare sector provides new insights into a field that is often considered a “blackbox”. This thesis adds to the topic in three essays, each focusing on a different aspect and depth level ranging from a macro perspective on healthcare innovation on a global scale to a meso level perspective on the implementation of personalized medicine in one country and putting a micro lens on innovation activities of hospital staff. The aim of this thesis is to provide an overview for researchers, policy makers and healthcare stakeholders about current developments, propose tools for measuring innovation and allow for benchmarking the current status quo in healthcare in order to foster new and innovative developments.

Background: The agro-food sector faces several sustainability challenges and is in clear need of transitions to become more sustainable. A transition in food production, consumption and supply chains that demand fewer resources and fewer animal products is required to attain sustainability in the agro-food sector. This transition can be done by consuming more plant-based food and providing an alternate option to animal protein by substituting it with plant protein. Purpose: This study aims to understand the technological innovation system shaping around the value chain of Swedish legumes. To investigate the above aim, this research intends to address the following questions: RQ1: How is the innovation system built up, and how do the functions of the innovation system perform around the value chain of Swedish legumes? RQ2: What are the barriers connected to the innovation system that hinders the development of the value chain of Swedish legumes? Method: The methodology used was a qualitative case study with an abductive approach. The data was collected from 8 semi-structured interviews and a literature review of relevant articles. The empirical findings were then analysed using a framework based on Technology Innovation System (TIS). Implications: This research study describes the structural causes that form functional barriers in the innovation system that hinders the development of a value chain for Swedish legumes. The findings of this study provides an excellent opportunity for government agencies and policymakers to guide plans and actions through policies to provide incentives for farmers and research projects in favour of a sustainable transition towards more plant-based food. Also, our study contributes to an understanding of sustainability transitions in the Swedish agro-food sector by analysing how the TIS functions perform around the value chain of Swedish legumes.

Factors that could enable the development of a distribution system for hydrogen applied to heavy-duty vehicles in Sweden are studied in this thesis. Fuel cell and hydrogen technology could be a solution in an electrification mix to reduce the environmental impacts of heavy-duty vehicles (Neef, 2009). However, the distribution system for hydrogen in Sweden is limited, with only five hydrogen refueling stations geographically dispersed (Vätgas Sverige, n.d.). In addition, distribution options at the lowest-cost delivery mode are highly dependent on the hydrogen application, density of demand, quantity to be transported, and distance between the delivery point and the production (Bersani, et al., 2018) To determine what factors could be decisive to develop a distribution system, the technological innovation system framework has been applied in this study. The analysis is carried out with the framework’s system functions. Further, the analysis is based on literature on hydrogen that considers hindering factors and barriers, policy recommendations, lock-in effects, distribution and transportation, and centralized vs. de-centralized systems. Moreover, data has been collected through 11 semi-structured interviews with actors from different sectors, energy companies, truck manufacturers, and researchers, amongst others. The analysis concludes that cross-sectoral collaboration, pilot testing, and governmental support can be enabling factors for the development of a distribution system in Sweden. / Faktorer som kan möjliggöra utvecklingen av ett distributionssystem för vätgas applicerat för tunga fordon i Sverige studeras i den här studien. Tekniken för bränsleceller och vätgas kan vara en lösning i en elektrifieringsmix för att minska miljöpåverkan från tunga fordon (Neef,2009). Distributionssystemet för vätgas i Sverige är dock begränsat, med endast fem vätgastankstationer som är geografiskt spridda (Vätgas Sverige, n.d.). Dessutom är distributionsalternativen till lägst kostnad i hög grad beroende av väteapplikationen, efterfrågan, kvantitet som ska transporteras och avståndet mellan leveranspunkten och produktionen (Bersani, et al., 2018). För att avgöra vilka faktorer som kan vara avgörande för att utveckla ett distributionssystem har ramverket för teknisk innovation system tillämpats i den här studien. Analysen utförs med ramverkets systemfunktioner. Vidare baseras analysen på litteratur om väte som tar hänsyn till hindrande faktorer och barriärer, policyrekommendationer, lock-in-effekter, distribution och transport och centraliserade kontra decentraliserade system. Dessutom har data samlats ingenom 11 halvstrukturerade intervjuer med aktörer från olika sektorer, energibolag, lastbilstillverkare och forskare, bland annat. Utifrån analysen dras slutsatsen att sektorsövergripande samarbete, pilottestning och statligt stöd är faktorer som kan möjliggöra en utveckling av ett distributionssystem för vätgas i Sverige.

This thesis explores the factors contributing to successful collaboration within the Quadruple and Quintuple Helix frameworks, with a specific focus on the active involvement of students as stakeholders. A qualitative research approach was adopted, utilising interviews, questionnaires, and action research documented in a diary form, to gather data. The study examines the Creative LAB, an innovation lab initiated by students in the Innovation and Design master’s program at Mälardalens University, as a base for the collaborations with which the data is inquired from. The research employs the Quadruple and Quintuple Helix models as theoretical frameworks to understand collaboration dynamics. Phenomenographic analysis was used to categorise and analyse the experiences of collaboration. The interviews and questionnaires, both addressing the same topic, were transcribed, and subjected to systematic extraction and analysis. The findings are presented in the form of categories, supported by direct quotations and perspectives from the respondents. The research diary served as a reflective tool throughout the thesis, documenting and analysing the obtained results and the work conducted within the Creative LAB. It provided valuable insights into the collaboration dynamics, success factors, and the role of students as active stakeholders in the Quadruple and Quintuple Helix models. By capturing observations and personal reflections, the diary contributed to a deeper understanding of the research findings and enhanced the overall validity of the study. One of the projects, WellBot, is also presented as a case study. In summary, this thesis provides insights into the key success factors for collaboration within the Quadruple and Quintuple Helix frameworks, while also highlighting the significant role of students as active stakeholders. The results shed light on the perceptions and experiences of the participants, offering valuable implications for fostering effective collaboration in the context of academia, industry, and society. In the end, success-factors identified within the study is presented, as well as a questionnaire to identify perceptions on potential collaborations.

This study examined the dynamics, challenges and opportunities of developing innovation systems in low resource settings with a particular focus on Uganda. It applied perspectives of technoscience and concepts of innovation systems, triple helix as university-industry-government relationships, mode 2 knowledge production and situated knowledges in understanding the context, identifying key policy issues and suggesting ways to address them. A mixed methodology combining both quantitative and qualitative methods was used in the study. It involved review of key policy documents, key informant interviews, focus group discussions and meetings with scientists, business leaders in the target organizations and firms, community members as well as observations of production processes in firms. Findings underscore the need for greater interaction and learning among actors in the emerging innovation systems in Uganda and eastern Africa. An opportunity for this to happen may be the growing number of entrepreneurial initiatives at the university and some public research organizations in the country. These entrepreneurial initiatives are driven by scientists, who are enthusiastic about moving their research results and innovations to market. This makes it plausible, in low resource settings like in Uganda, to promote the university working closely with public research organizations and firms as a locus for research and innovation. However, enabling conditions, which foster interaction and learning among actors, should be put in place. First, there is need to formulate specific policies and strategies with clear goals and incentives to promote growth of particular innovation systems. Second, a clear national policy for financing research and innovation is needed, which involves on the one part core funding to universities and research organizations, and on the other, competitive grants for research and innovation. Third, business incubation services should be established and/or supported as places where entrepreneurial scientists and other persons develop and test their business ideas and models. Fourth, there is need for institutional reforms to make administrative processes less bureaucratic, more costeffective and efficient. These reforms are necessary for example in processes involving procurement and financial management, research project approvals (for ethics and safety), technology assessments, contracting and licensing and other registration services. The findings and conclusions from this study demonstrate that technoscientific perspectives and innovation systems approaches can be adapted and used as a framework for identifying and explaining conditions that promote or hamper innovation in low resource settings as well as policy options to address them.

科技競爭力是經濟持續成長的動力，而政府、企業與國家之整體科技能量為發展科技經濟的重要支柱。於全球科技經濟的持續發展之下，研發（R&D）的投入、創新（Innovation）的擴散，並逐漸在以知識（Knowledge）作為競爭基礎的全球化社會與網際網路時代中日益重要，而在此趨勢之下，企業除了應積極規劃產業轉型，政府創新政策（Innovation Policy）的支持更是不可或缺的條件，各國家莫不體認到「創新能力」是現代國家競爭力的重要關鍵。 美國在甘乃迪總統時代，便將「創新政策（Innovation Policy）」視為政府產業科技政策中非常重要的一環，其目的在獎勵新興產業中之科技創新，因其能符合國家的需求及達到改善經濟情勢的目標，但由於私人企業的資源有限，無法在有限的時間及預算內開發出符合社會大眾需求的產品。所以，甘乃迪主張政府應負責主導產業科技創新發展的方向，同時政府應提供企業界財力及其它資源上的補助。 創新相關的概念逐步發展，到晚近十多年，西歐幾個國家包括丹麥、瑞典和英國的產業經濟與政策研究學者，開始提倡「國家創新系統（National Innovation System）」的概念。過去，人們直接將科學系統（Science system）視為唯一的創新指標（Innovation indicator），科學投入（Science input，如R&D預算）的增加直接助長創新及科技的發展。這個以科技推力為主的簡單線性關係模型的觀念已被「系統式模式（Systemic approaches）」所取代。 亦即創新為研究、發展、行銷、擴散（Research, development, marketing, diffusion）每一階段交互作用的成果，而非單單是R&D的投入面而已，也就是說創新活動來自創新系統（Innovation system）中每一成員（如政府、大學、私人企業）及每一步驟（研究、發展、行銷、擴散）的交互作用等，而不只是學術界與R&D的事而已。 歐州近年來針對創新政策相關議題多所著墨，而自2000年開始，荷蘭、比利時是歐洲中於國家競爭力上有卓越表現的國家，而基於版圖規模和經濟特質，在科技產業之推動與創新政策之發展上，以上各國顯然有許多值得臺灣借鏡與學習的地方，本研究期望對荷蘭、比利時二國創新政策做深入淺出的剖析，並以國家創新系統為依歸，歸納出對正努力邁向知識密集、附加價值的臺灣一個值得參考之啟示與學習典範。 / Technological competitive strength is the power for the continuous growth of the economy. And the technological power of the government, enterprises and the country is the critical mainstay of the development of technological economy. Under the continuous development of the world economy, the investment on R&D and the spread of innovation become more important in the competition with the knowledge base in the global world and internet era. Under this trend, besides planning the transform of the products, the enterprise needs the government's Innovation Policy as a necessary factor. All the countries realize that Innovation is the key to the modern nations' competitive strength. During the Kennedy period, the U.S. regards Innovation Policy as a most important part of the government's high-technology industry. The aim is to encourage the technological innovation in the new industry, because it conforms to the country's needs and may improve the economic condition. However, as the private enterprises have limited power and cannot produce the products conforming with people's needs during a time limit. Therefore, Kennedy advocates that government should be responsible to lead the industrial technology, and provides some monetary and other aids. Concepts relating to innovation are gradually developing. In the recent ten years, theory studying scholars from western European countries, including Denmark, Sweden and U.K., begin to advocate National Innovation System. In the past, people regard Science system as the only Innovation indicator, thinking that the growth of Science input will directly foster innovation and the development of technology. This simple linar model has already been replaced by Systemic approaches; that is, innovation is not the result by R&D but the result of the co-operation of research, development, marketing, diffusion. It can also be interpreted that innovation comes from every single member (such as the government, university, private enterprise) and every step, not just the academic circles and R&D. In the recent years, Europe has a lot of works on innovation policy. Since 2000, Netherlands and Belgium are marvelous countries. As for the domain size and the economy quality, Taiwan needs to learn from the above countries on the development of technology industry and innovation policy. The research expects deep analysis on the innovation policies of this three countries; in the meantime, arranges a valuable example for Taiwan on the way to knowledge-intensive and value added.

Since China embraced the “Open Door” policy in 1978, innovation has been an increasingly important factor for the Chinese economy. China is now the third largest country in the world league table of patent applications. China has also received large amounts of foreign direct investment, much of it from major Western innovative companies. In the earlier years of the Open Door policy, much of the involvement of Western companies was through joint ventures. International joint ventures are still important, and it is believed have substantially enhanced China's innovative capability. It is the contention of this research that there is a direct correlation between the arrivals of Sino-Western JVs and China's increased innovation capabilities. This is an important area of study as China moves towards becoming a developed economy. The gap in research at present is in applying innovation theory to China and to JVs. The thesis explores the contribution of Sino-Western JVs to the development of China's innovative capabilities. A model of the innovation process is developed, and eight important factors that are considered to enhance a company's innovative capacity, are derived from the model. The factors, expressed as propositions, are: 1: Becoming part of a wide innovative network in its industry 2: Taking part in an open innovation system in its industry 3: Relating closely to universities, and particularly their research laboratories 4: Relating closely to research institutions 5: Developing a social atmosphere conducive to innovation 6: Developing a strong strategic planning system with innovation as a focus 7: Having innovation as a primary objective of both partners at the outset of the joint venture 8: Focusing on developing intellectual property To investigate whether these propositions were accepted by Sino-Western joint ventures, 40 semi-structured interviews were conducted in ten international (Sino-western) joint ventures in China. In general the interviews provided support for the propositions. However, some reservations were expressed. Executives were reluctant to engage in open (collaborative) innovation, preferring to seek patents for developed intellectual property. They also perceived the main objective of the Western partners to be commercial success rather than innovation, although the Chinese partners were very much innovation-orientated. The research contributes to our understanding of the contribution of Sino-western JVs to the innovative capability of Chinese companies, and provides support for most of the propositions identified in the literature. Respondents remarked that most of the propositions would apply also to self-standing companies in China, and suggested that joint ventures could stimulate innovation in indigenous Chinese companies. In addition to providing a historical overview of the development of innovation in China, developing an innovation process model and testing it in the Chinese context, the thesis makes important policy and practical recommendations to Chinese organizations.

Made available in DSpace on 2015-03-05T18:41:01Z (GMT). No. of bitstreams: 0 Previous issue date: 19 / Nenhuma / Atualmente o tema da inovação vem sendo discutido intensamente na academia e no meio empresarial. Neste contexto o presente estudo propõe um modelo de SCI – Sistema Corporativo de Inovação estruturado a partir da literatura e das percepções do autor. Esse modelo é composto por oito variáveis: Conceitos/Objetivos, Estratégia, Estrutura Organizacional, Gestão da Inovação, Indicadores, Gestão do Conhecimento para Inovação, Comunicação e Relacionamento Externo. O teste do modelo foi realizado em uma empresa industrial que possui três subsistemas estruturados de inovação (P&D, SPF e Inovação Industrial). Cada um desses subsistemas possui objetivos, métodos e ferramentas específicas. A pesquisa foi realizada visando o entendimento desses subsistemas sob a ótica do SCI proposto. A conclusão do trabalho pode ser sintetizada em quatro tópicos: i) a utilização do modelo SCI permite a empresa realizar uma análise estruturada e sistêmica sobre a inovação; ii) o modelo SCI tendeu a mostrar-se coerente com a teoria consult / Currently the subject of innovation has been intensely discussed in the academy and in the business environment. In this context the present study suggest a model of CIS - Corporate Innovation System structuralized from the literature and from the author perspectives. This model consists in eight variables: Concepts/Objectives, Strategy, Organization Structure, Innovation Management, Indicators, Knowledge Management for Innovation, Communication and External Relationship. The test of the model was carried through an industrial company that has three structuralized subsystems of innovation (P&D, SPF and Industrial Innovation). Each one of these subsystems has objectives, methods and specific tools. The research was made willing the understanding of these subsystems under the view of the CIS suggested. The conclusion of the work can be summarized in four topics: i) the use of the CIS model allows the company to do a structured and systematical analysis of the innovation; ii) the model CIS tended to reveal cohe

A área da saúde é considerada um dos setores econômicos mais dinâmico em termos de inovação e de acumulação de capital. Desta forma, a compreensão de sua estrutura e funcionamento é indispensável para a construção de políticas efetivas de promoção do bem-estar e do desenvolvimento dos países no âmbito dos Sistemas de Inovação em Saúde (SIS). O progresso tecnológico do setor de saúde vincula-se fortemente à ciência, tendo o advento da biotecnologia moderna acentuado a relação entre ciência e tecnologia para a pesquisa e a inovação médica, sendo que a inovação na área da saúde depende de pesquisas interdisciplinares e das interações entre indústrias e universidades, especialmente centros médicos acadêmicos, que atuam como centros de convergência de fluxos de informação científica e tecnológica. As pesquisas médica e biomédica no Brasil, a despeito de seu progresso em publicações científicas, apresentam caráter predominantemente acadêmico devido, em parte, ao fato de não existir suporte adequado à proteção à propriedade intelectual e ao reconhecimento de patentes no país. Neste sentido, a presente pesquisa tem como objetivo verificar como um empreendimento de base biotecnológica do segmento de fármacos é influenciado pelo SIS onde está inserido, tomando-se como objeto de estudo uma empresa desenvolvedora de produtos para oncologia, identificada aqui com o nome fictício de BIOTEC. Para tanto, foi realizado um estudo qualitativo e exploratório de caso único em duas etapas, a primeira envolvendo pesquisas em fontes de dados secundários e a segunda composta por entrevistas em profundidade com uma das empreendedoras da empresa BIOTEC e com a Gerente da Incubadora Empresarial do Centro de Biotecnologia da UFRGS (IECBiot), um dos parceiros da empresa e um importante ator dentro do Sistema Regional de Inovação em Saúde do Rio Grande do Sul (SRIS-RS). A partir das respostas obtidas, foi possível compreender como se dá a interação da empresa com outros atores do SIS brasileiro, em nível nacional e regional. Verificou-se também que,devido à existência de obstáculos associados ao excesso de burocracia e à dificuldade de ao acesso a fomento e incentivos no estado do RS, este não apresenta um ambiente propício ao desenvolvimento de empresas com o perfil da BIOTEC e que, apesar de existirem esforços do governo estadual em melhorar a situação do SRIS-RS, estas ainda se encontram aquém do necessário, fazendo com que, muitas vezes, as empresas optem por buscar ambientes mais favoráveis aos negócios. / The healthcare sector is one of the most dynamic sectors of the economy in terms of innovation and capital accumulation. Thus, understanding its structure and operation is essential for building effective policies to promote the welfare and development of countries under the health innovation systems (SIS). Technological progress in the healthcare sector binds strongly to science, with the advent of modern biotechnology marking the relationship between science and technology for research and medical innovation. Innovation in healthcare depends on interdisciplinary research and interactions between industries and universities, especially academic medical centers, which act as convergence centers of scientific and technological information flows. The medical and biomedical research in Brazil, despite its progress in scientific publications, have predominantly academic character, in part due to the fact that there isn’t adequate support for intellectual property protection and recognition of patents in the country. This way, this research aims to check how a biotechnology-based enterprise, focused on the production of drugs, is influenced by the HIS where it’s localized, taking as object of study a company that develops products for oncology, here identified with the fictitious name of BIOTEC. Therefore, it was conducted a qualitative and exploratory study of a single case in two stages, the first involving research on secondary data sources, and the second consisting of interviews with the entrepreneurs of BIOTEC company and the manager of the Business Incubator of the Biotechnology Center from UFRGS (IECBiot), one of the company partners and a major player within the health regional innovation system in the Rio Grande do Sul (SRIS-RS). From the answers obtained, it was possible to understand how is the company's interaction with the other actors of SIS, at the national and regional level. It was also found that, due to barriers associated with excessive bureaucracy and the difficulty to access finance promotion and incentives, the Rio Grande do Sul state doesn’t provide an appropriate environment to the development of companies with the BIOTEC’s profile. Although there are government efforts to improve the situation of SRIS-RS, they are still insufficient, which often make the companies choose to seek more favorable environments for business.