Made available in DSpace on 2014-06-11T19:26:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-07-15Bitstream added on 2014-06-13T20:33:53Z : No. of bitstreams: 1 ivani_sa_me_jabo.pdf: 806885 bytes, checksum: 46ae5805f566147f2c05b8acbfd80a9e (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / O objetivo do presente trabalho foi estudar a divergência genética por meio de caracteres morfológicos de frutos, diásporos, ráquilas e plântulas, entre palmeiras matrizes de Oenocarpus bacaba Mart., em três populações naturais do Amapá, Comunidade Lontra da Pedreira, Parque Zoobotânico em Macapá e Município de Porto Grande. A divergência genética foi avaliada pela análise de agrupamento, através do algaritmo de Tocher e do método do Ward, obtido a partir da matriz de dissimilaridade pela Distância Euclidiana. A técnica dos componentes principais foi utilizada para identificar a importância relativa de cada variável para a divergência genética. Houve certa concordância nos dois métodos de agrupamento. Dos 17 caracteres avaliados 10 deles (60%) são passíveis de descarte nas três áreas de estudo / The objective of this work was to study the genetic divergence for morphological characters of fruits, disseminules, rachilles and seedlings, among matrices of Oenocarpus bacaba Mart. palm, in three natural populations of Amapa city, Lontra da Pedreira community, Park Zoobotany in Macapa and Porto Grande municipality. The genetic divergence was assessed by clusters analysis by the Tocher algaritmo and Ward's method, obtained from the matrix of dissimilarity of the Euclidian distance. The technique of principal components was used to identify the relative importance of each variable for genetic divergence. There was some agreement among the two groups The twenty characters evaluated, 10 of them (60%) are likely to discard of the three areas of study

The thesis is primary focused on the integrated data warehouse, particularly on a subset -- dependent data marts. The main objectives of this thesis are design the methodology of development and maintenance of dependent data marts and verification methodology usefulness in the real organization. The first part deals with the theoretical definition of terms. It focuses particularly on the definition of terms from Business Intelligence area especially data warehousing and data marts. Each of the terms is described in detail in separate chapters. Business Intelligence area puts emphasis on description of individual components. In data warehousing area are described the data warehouse concepts and content of layers in a data warehouse. Finally, the data mart area is designed to describe dependent and independent data marts and also "special "cases of data marts, likely the semantic layer, and a sandbox. The second part focuses on the design methodology itself. At the beginning of this part is analysis of the existing methodologies and assess their usefulness with connection to designed methodology. The following part describes the current situation in the approach to the development and maintenance of dependent data marts in the organization. At the end of the second part is designed own methodology, which is based in part on the analysis methodology and in part on the analysis of current situation. The third part focuses on usability and usefulness evaluation of methodology in the organization. Evaluation is based on the methodology of criticism from employees in the organization who are directly engaged in designing and maintaining dependent data marts. Finally, the fourth and final part will focus on the description of an alternative solution that could be considered as one of the ways to sustainable development of data warehouse in the organization. It's about comparison architecture based on utilization of semantic layer as oppose to the "three layers" concept of data warehouse by Bill Inmon, which is implemented in the organization. The output evaluates alternative solutions to the current solution.

El presente proyecto, tiene como objetivo generar una propuesta de mejora del proceso de logística de entrada bajo las buenas prácticas del modelo SCOR para una consultora de tecnología en Lima con la finalidad optimizar la elaboración de información estratégica generada por este proceso. Como parte de esta propuesta, se desarrollará un Data Mart que permitirá agilizar la obtención de estos datos. La logística de entrada, compuesta por la gestión de compras e inventario, genera información estratégica que es relevante y solicitada por áreas del negocio como comercial, proyectos y gerencia general. Hoy en día este proceso se ve afectado por los altos tiempos y la mala planificación del área para realizar sus actividades de registro y control de información lo que impide que posteriormente se pueda consultar de manera rápida e integra. Esto finalmente afecta que se pueda realizar una toma de decisiones en certidumbre. La aplicación de las buenas prácticas del modelo SCOR al proceso logístico, demostraron que se puede disminuir el porcentaje actual de tiempo de registro de información en un 35%. También mediante la aplicación del Data Mart, los porcentajes de gastos operativos y tiempos para elaborar información estratégica se reducen en un 97% y 96% respectivamente. De esta manera la propuesta demuestra su efectividad permitiendo optimizar la elaboración de información estratégica del área para así poder tomar mejores decisiones en beneficio del negocio. / The object of this project is to generate a proposal to improve the inbound logistics process under the best practices of the SCOR model for a technology consultancy in Lima in order to optimize the development of strategic information generated by this process. As part of this proposal, a Data Mart will be developed to expedite the collection of this data. Inbound logistics is made up of purchasing and inventory management. This process generates strategic information that is relevant to business areas such as commercial, projects and general management. Today this process is affected by high times and poor planning of the area to carry out its activities of registration and control of information, which generates that later it can’t be consulted quickly and integrated. This directly affects decision-making. The application of SCOR model good practices to the logistics process, showed that the current percentage of time for entering information can be reduced by 35%. Also, through the implementation of the Data Mart, the percentages of operating costs and times to generate strategic information are reduced by 97% and 96% respectively. In this way the proposal demonstrates its effectiveness allowing to optimize the elaboration of strategic information of the area in order to be able to take better decisions in benefit of the business. / Tesis

This ethnography is a study of the cultural scene at one store of a chain of twenty-eight retail "discount department stores"--the Bi Mart Company, a subsidiary of the Pay 'n Save Corporation. It is an exercise of an ethnographic method developed by James Spradley that is used to uncover and describe the cultural grammar of acquired knowledge which Bi Mart employees use to define and interpret their situation and to generate and understand their work. The method is based on the assumption that culture is best learned and best described (as much as possible) from the "native" point of view.

This is an interdisciplinary master's level thesis that explores links among technical writing, training manuals, surveillance, and anti-union rhetoric used with service workers in select American chains and franchises. Brief histories are provided, including those of technical writing, the rise of unions in America, and how technical writing became inextricably linked with labor. A major shift occurred in the 20th century when workers began interacting less with products and more with the public. The research focuses on training manuals, techniques, and rehearsed dialogues of McDonald's, Wal-Mart, Starbucks, Whole Foods, Panera, and Publix, though similar organizations are referenced. Service worker language, uniforms, and store decorum are sometimes analyzed for their rhetorical content. The idea of a single, technically written training manual in the service sector is a misnomer; training is delivered through a pastiche of manuals, videos, computers, apps, flipcharts, and on the job training. Unions are avoided through franchising (and therefore eat outlet not possessing enough workers to organize), creating conditions of high turnover rates, rhetoric, and use of euphemism. Global corporations are likened to "superfiefdoms," with service workers equated to modern serfs. If the world has evolved into supercorporations, it is argued then that the Publix employee-owned model may be the best approach and the most dignified of all. The technical writing and instruction in state-sponsored and federalized school pedagogies, which emphasize drills and compliance, may be culturally linked to the training found in these entry-level service jobs, and more academic study exploring these links is called for.

No description available.

Considerando o grave quadro das doenças negligenciadas, no Brasil e no mundo, e as limitações do tratamento empregado, na atualidade, torna-se urgente a pesquisa de novos fármacos, que sejam mais ativos e seguros. Para tanto, a busca de moléculas-protótipo, a partir de espécies vegetais, tem sido importante estratégia. Neste contexto, foi realizado o estudo de Annona crassiflora Mart. (Annonaceae), cujos alcalóides totais (AT) demonstraram promissora atividade antiprotozoária in vitro, em estudo anterior. Em paralelo, outras espécies de Annona mostraram atividade antimicobacteriana in vitro, igualmente, tendo motivado o presente estudo. Cinco das vinte frações alcaloídicas obtidas, por cromatografia em coluna, a partir dos AT das folhas, apresentaram atividade anti-Leishmania in vitro, tendo causado 100% de morte das formas promastigotas de Leishmania (L.) infantum chagasi. Além disto, três delas foram ativas frente ao Mycobacterium tuberculosis. O isolamento de dois alcalóides noraporfínicos foi realizado, por fracionamento biomonitorado em coluna cromatográfica, seguido de cromatografia líquida de alta eficiência (CLAE) semipreparativa. As estruturas dos compostos isolados foram elucidadas empregando-se as análises espectroscópicas de ressonância magnética nuclear, mono e bidimensionais, e por CLAE acoplada à espectrometria de massas (CLAEIES-EM2). Um dos alcalóides foi identificado pela primeira vez, nesta espécie, sendo que o outro apresentou estrutura inédita. Ambos demonstraram significativa atividade anti-Leishmania in vitro (CE50≤ 10 µ g/ mL) frente às formas promastigotas de L. (L.) infantum chagasi [MHOM/BR/1972/LD]. O primeiro teve maior índice de seletividade (IS: 7,4), em relação à citotoxicidade em células do tecido conjuntivo NCTC Clone 929 de camundongos. Frente ao Mycobacterium tuberculosis (ATCC 27294) e ao M. smegmatis (ATCC 35798), os alcalóides isolados foram inativos (CIM ≥ 128 µg/ mL). O óleo volátil das folhas foi analisado por cromatografia gasosa acoplada à espectroscopia de massas (CG-EM), tendo sido identificados 41 constituintes, prevalecendo os sesquiterpenos (81,7%) em relação aos monoterpenos (0,8%). Entre os compostos majoritários encontrados no óleo, citam-se os sesquiterpenos α-amorfeno (43,6%), E-cariofileno (17,7%) e o germacreno (5,3%). Nos testes de atividade anti-Leishmania in vitro frente às formas promastigotas de quatro espécies do parasita, o óleo foi mais ativo em L. (L.) infantum chagasi (CE50: 25,97 µg/ mL). Nas formas tripomastigotas do Trypanosoma cruzi mostrou atividade 8,5 vezes superior àquela do fármaco-padrão benznidazol (CE50: 5,31 µg/ mL). Os resultados obtidos ratificaram a importância da prospecção da flora, em particular de A. crassiflora, como fonte potencial de compostos bioativos, que venham a constituir novos fármacos, como alternativa à restrita terapêutica existente para o tratamento das doenças negligenciadas. / Neglected diseases are a serious health problem in Brazil and worldwide. The available drugs are limited in effectiveness with a high toxicity. There is an urgent need of more safe and bioactive compounds. The search of new molecules from plant species is a well known and important strategy to achieve this goal. In a previous work, Annona crassiflora Mart. (Annonaceae) showed a promising antiprotozoal activity. Beside this, other Annona species presented an interesting antimicobacterial action. In this bio-guided study, after the column fractionation of the leaves total alkaloids, in vitro tests were performed and five from twenty fractions were highly active (100% deaths) against promastigotes of Leishmania (L.) infantum chagasi, and only three were active against Mycobacterium tuberculosis. After purification of the bioactive fractions, two noraporphine alkaloids were isolated by HPLC and identified by the usual mono and bidimensional spectroscopic techniques. One of them was isolated from the first time from this species. The other one is a novel chemical entity. Both compounds presented anti- Leishmania activity (CE50 ≤ 10 µg/ mL) against L. (L.) infantum chagasi [MHOM/BR/1972/LD]. The first one showed a higher selectivity index (SI: 7.4) considering its mice connective tissue cells toxicity [NCTC Clone 929]. However, both were inactive against Mycobacterium tuberculosis (ATCC 27294) and M. smegmatis (ATCC 35798) (CIM ≥ 128 µg/ mL). In the leaves volatile oil 41 compounds were identified. The sesquiterpenes were in majority (81.7%), followed by monoterpenes (0.8%). The sesquiterpenes α-amorphene (43.6%), E-caryophyllene (17.7%) and germacrene (5.3%) were the main constituents. The oil was little effective against the four tested Leishmania species and slightly more active against L. (L.) infantum chagasi (CE50: 25.97 µg/ mL). However, it was highly active against the trypomastigotes of Trypanosoma cruzi (CE50: 5.31 µg/ mL) showing to be 8.5 times more active than benznidazol. These results stimulate a deeper investigation of those alkaloids as antiprotozoal agents, confirming the importance of the plant species metabolites as a source of new bioactive molecules and their potential as future drugs.

Considerando o grave quadro das doenças negligenciadas, no Brasil e no mundo, e as limitações do tratamento empregado, na atualidade, torna-se urgente a pesquisa de novos fármacos, que sejam mais ativos e seguros. Para tanto, a busca de moléculas-protótipo, a partir de espécies vegetais, tem sido importante estratégia. Neste contexto, foi realizado o estudo de Annona crassiflora Mart. (Annonaceae), cujos alcalóides totais (AT) demonstraram promissora atividade antiprotozoária in vitro, em estudo anterior. Em paralelo, outras espécies de Annona mostraram atividade antimicobacteriana in vitro, igualmente, tendo motivado o presente estudo. Cinco das vinte frações alcaloídicas obtidas, por cromatografia em coluna, a partir dos AT das folhas, apresentaram atividade anti-Leishmania in vitro, tendo causado 100% de morte das formas promastigotas de Leishmania (L.) infantum chagasi. Além disto, três delas foram ativas frente ao Mycobacterium tuberculosis. O isolamento de dois alcalóides noraporfínicos foi realizado, por fracionamento biomonitorado em coluna cromatográfica, seguido de cromatografia líquida de alta eficiência (CLAE) semipreparativa. As estruturas dos compostos isolados foram elucidadas empregando-se as análises espectroscópicas de ressonância magnética nuclear, mono e bidimensionais, e por CLAE acoplada à espectrometria de massas (CLAEIES-EM2). Um dos alcalóides foi identificado pela primeira vez, nesta espécie, sendo que o outro apresentou estrutura inédita. Ambos demonstraram significativa atividade anti-Leishmania in vitro (CE50≤ 10 µ g/ mL) frente às formas promastigotas de L. (L.) infantum chagasi [MHOM/BR/1972/LD]. O primeiro teve maior índice de seletividade (IS: 7,4), em relação à citotoxicidade em células do tecido conjuntivo NCTC Clone 929 de camundongos. Frente ao Mycobacterium tuberculosis (ATCC 27294) e ao M. smegmatis (ATCC 35798), os alcalóides isolados foram inativos (CIM ≥ 128 µg/ mL). O óleo volátil das folhas foi analisado por cromatografia gasosa acoplada à espectroscopia de massas (CG-EM), tendo sido identificados 41 constituintes, prevalecendo os sesquiterpenos (81,7%) em relação aos monoterpenos (0,8%). Entre os compostos majoritários encontrados no óleo, citam-se os sesquiterpenos α-amorfeno (43,6%), E-cariofileno (17,7%) e o germacreno (5,3%). Nos testes de atividade anti-Leishmania in vitro frente às formas promastigotas de quatro espécies do parasita, o óleo foi mais ativo em L. (L.) infantum chagasi (CE50: 25,97 µg/ mL). Nas formas tripomastigotas do Trypanosoma cruzi mostrou atividade 8,5 vezes superior àquela do fármaco-padrão benznidazol (CE50: 5,31 µg/ mL). Os resultados obtidos ratificaram a importância da prospecção da flora, em particular de A. crassiflora, como fonte potencial de compostos bioativos, que venham a constituir novos fármacos, como alternativa à restrita terapêutica existente para o tratamento das doenças negligenciadas. / Neglected diseases are a serious health problem in Brazil and worldwide. The available drugs are limited in effectiveness with a high toxicity. There is an urgent need of more safe and bioactive compounds. The search of new molecules from plant species is a well known and important strategy to achieve this goal. In a previous work, Annona crassiflora Mart. (Annonaceae) showed a promising antiprotozoal activity. Beside this, other Annona species presented an interesting antimicobacterial action. In this bio-guided study, after the column fractionation of the leaves total alkaloids, in vitro tests were performed and five from twenty fractions were highly active (100% deaths) against promastigotes of Leishmania (L.) infantum chagasi, and only three were active against Mycobacterium tuberculosis. After purification of the bioactive fractions, two noraporphine alkaloids were isolated by HPLC and identified by the usual mono and bidimensional spectroscopic techniques. One of them was isolated from the first time from this species. The other one is a novel chemical entity. Both compounds presented anti- Leishmania activity (CE50 ≤ 10 µg/ mL) against L. (L.) infantum chagasi [MHOM/BR/1972/LD]. The first one showed a higher selectivity index (SI: 7.4) considering its mice connective tissue cells toxicity [NCTC Clone 929]. However, both were inactive against Mycobacterium tuberculosis (ATCC 27294) and M. smegmatis (ATCC 35798) (CIM ≥ 128 µg/ mL). In the leaves volatile oil 41 compounds were identified. The sesquiterpenes were in majority (81.7%), followed by monoterpenes (0.8%). The sesquiterpenes α-amorphene (43.6%), E-caryophyllene (17.7%) and germacrene (5.3%) were the main constituents. The oil was little effective against the four tested Leishmania species and slightly more active against L. (L.) infantum chagasi (CE50: 25.97 µg/ mL). However, it was highly active against the trypomastigotes of Trypanosoma cruzi (CE50: 5.31 µg/ mL) showing to be 8.5 times more active than benznidazol. These results stimulate a deeper investigation of those alkaloids as antiprotozoal agents, confirming the importance of the plant species metabolites as a source of new bioactive molecules and their potential as future drugs.

Made available in DSpace on 2011-05-04T12:36:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2009 / O objetivo deste trabalho é apresentar os passos necessários para a construção de data marts /data warehouses como uma solução para um ambiente de suporte à decisão. Seu foco não é, entretanto, o aprofundamento de cada uma das etapas deste método (uma vez que existe uma ampla literatura sobre o assunto), mas realçar a importância do envolvimento do usuário aqui denominado consumidor da informação durante o processo de criação e manutenção destes data marts / data warehouses. O consumidor da informação é chamado a participar de um plano integrado com os membros das áreas detentoras do conhecimento necessário para a construção destas soluções de suporte à decisão, incluindo a área de tecnologia da informação. A disseminação das informações contidas nestes bancos de dados para os diversos tipos de consumidores da informação(com diferentes recursos de hardware, software e humanos disponíveis), e sua aplicação no controle social, também são discutidas aqui. / The purpose of this work is to present the required steps for the construction of data marts / data warehouses as a solution for a decision support environment. However, its focus is not to go deeper in each of the steps of this method (since there is a broad literature about the subject), but to highlight the importance of the user – here called information consumer – engagement during the process of creating and maintaining these data marts / data warehouses. The information consumer is called to take part in an integrated plan together with the members of the areas who own the necessary knowledge to build these decision support solutions, including the information technology (IT) area. The spread of the informations contained in these databases to the different types of information consumers (with different hardware, software and human resources available), and its application in social control, is also discussed here.

Made available in DSpace on 2016-04-26T18:18:23Z (GMT). No. of bitstreams: 1 Desire Blum Menezes Torres.pdf: 8617965 bytes, checksum: 700ef00066cfcc6bbe0143e8870f2557 (MD5) Previous issue date: 2009-12-14 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / This work complies with the intent of studying, in terms of language, the contrivances used by supermarket network to establish relationships and communication with the environment around them within the atmosphere of a mixed society. We compared two establishments in the city of Curitiba, Brazil: a national network and another pertaining to an offshore network. The assumption that edges the research is that, since this kind of supermarket displays the characteristic of non communication with external ambiances - unlike a local grocery store or a market place where the service is personalized and engaging - human relations in their environment are depthless, superficial or even nonexistent. In a society that tends towards the hybridization of typical composé of Latin American cities, in which the cultural blend is evident in urban areas, the understanding of how the supermarket network deals with this multiplicity and participates in several series to raise cultural leans towards expressive contrasts. The research is exploratory and explanatory, with empirical observation supported by photographic record. The theoretical and methodological framework is based on sources developed by Latour, Canevacci, Ferrara and Rennó, leading the analysis of urban culture from the point of view of the observation of the image. The concepts of fusion of culture and cultural studies, with the metaphors generated by the same provide the mechanisms of translational identified phenomena. The procedure of analysis is enriched by the contributions of Laplantine, Nous, Martín- Barbero, Gruzinski and Pinheiro. Another significant theoretical core under analysis was obtained in systems theory, with Vieira, Uexkull and Bunge. Urban space, center and periphery, mixed borders, consumer relations and the concept of non-place comes from the theoretical constructs of Certeau, Canevacci, Santos, Ferrara, Lotman, Delgado, Silva, Bauman, Underhill, Webber and Augé. The analysis of this study envisages the fact that the supermarket networks, domestic or offshore are not related to the individual as a customer, which is contradictory in societies that tend towards the hybridization of forms, such as Latin societies. At the national supermarket under analysis, were found embedded cultural series, but in an offshore network, these elements are not valued, as happens with the external aspects of local culture. Based on the systemic point of view and cultural studies, it can be said that these environments present themselves as non-places / Este trabalho tem como objetivo estudar, do ponto de vista de linguagem, o modo como os supermercados de rede estabelecem relações e se comunicam com o ambiente que os circunda, na atmosfera de uma sociedade mestiça. São comparados dois estabelecimentos na cidade de Curitiba-PR: um de rede nacional e outro de rede estrangeira. O pressuposto que norteia a investigação é o de que, em virtude de esse gênero de supermercado apresentar a característica de não se comunicar com o lado de fora diferentemente de uma mercearia de bairro ou um mercado municipal, em que o atendimento é personalizado e envolvente , as relações humanas em seu ambiente são despersonificadas, superficiais ou mesmo inexistentes. Em uma sociedade que tende à hibridização de formas típica das cidades latino-americanas, nas quais a mestiçagem cultural é manifesta nos espaços urbanos, a compreensão de como o supermercado de rede lida com essa multiplicidade e participa de várias séries culturais permite levantar contrastes expressivos. A pesquisa é de natureza exploratória e explicativa, com observação empírica sustentada no registro fotográfico. A fundamentação teóricometodológica tem base em fontes desenvolvidas por Latour, Canevacci, Ferrara e Rennó, que conduzem a análise da cultura urbana sob o ponto de vista da observação da imagem. Os conceitos de mestiçagem da cultura e os estudos culturalistas, com as metáforas a que dão origem, oferecem os mecanismos tradutórios dos fenômenos identificados. O procedimento de análise é enriquecido com as contribuições de Laplantine, Nous, Martín-Barbero, Gruzinski e Pinheiro. Outro fulcro teórico expressivo nas análises foi obtido na teoria sistêmica, com Vieira, Uexkull e Bunge. Espaço urbano, centro e periferia, fronteiras mestiças, relações de consumo e o conceito de não-lugar provêm dos construtos teóricos de Certeau, Canevacci, Santos, Ferrara, Lotman, Delgado, Silva, Bauman, Underhill, Webber e Augé. As análises deste trabalho apontam para o fato de que as redes de supermercado, nacional ou estrangeira, não se relacionam com o sujeito cliente, o que é contraditório em sociedades que tendem à hibridização de formas, como as sociedades latinas. No supermercado nacional analisado, foram encontradas séries culturais incorporadas, mas, na rede estrangeira, esses elementos não são valorizados, e sim, aspectos externos à cultura local. Com base na visão sistêmica e em estudos culturalistas, pode-se afirmar que esses ambientes apresentam-se como não lugares